Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-003767-9xbu4hnqLife history determines genetic structure and evolutionary potential of host- parasite interactions Are viruses alive?
cord-004914-cnz61qjyThe global mammal parasite database: an online resource for infectious disease records in wild primates Latitudinal gradients of parasite species richness in primates Infectious Diseases in Primates: Behaviour Ecology and Evolution Coevolution while you wait: Varroa jacobsoni, a new parasite of western honey bees Catastrophes after crossing species barriers Cross- species virus transmission and the emergence of new epidemic diseases Patterns of host specificity and transmission among parasites of free- living primates Infectious diseases and extinction risk in wild mammals Evolution of multiple components of virulence in Drosophila- nematode associations Effect of predator- prey phylogenetic similarity on the fitness consequences of predation: a trade- off between nutrition and disease?
cord-029032-s9geepscQß Conditions for invasion of synapse- forming HIV variants Fitness benefits of low infectivity in a spatially structured population of bacteriophages Are parasites"prudent"in space?
cord-013837-x95r6bz8This finding one to wonder why a mycobacteria departs from a cozy niche to enter the cytosol where it must confront a series of cytosolic immune sensors?
cord-102383-m5ahicqbHuman interactome of the influenza B virus NS1 protein Whither systems medicine?
cord-026880-i45okohfThe intestinal contortin structure in Haemonchus contortus: an immobilised anticoagulant?
cord-330590-nu8ckeudA comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
cord-048325-pk7pnmloWho mixes with whom?
cord-292657-gq3965seThe presence of SARS- CoV-2 RNA in feces of COVID-19 patients Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China Origin and evolution of pathogenic coronaviruses Phylogenetic network analysis of SARS- CoV-2 genomes Bat origin of human coronaviruses Influenza virus infectivity is retained in aerosols and droplets independent of relative humidity Effect of host species on the distribution of mutational fitness effects for an RNA virus Molecular evolution of MERS coronavirus: dromedaries as a recent intermediate host or longtime animal reservoir?
cord-264532-xfb94lq8: in pursuit of virulence management Challenging the trade- off model for the evolution of virulence: is virulence management feasible?
cord-264532-xfb94lq8How does recovery affect our model?
cord-290548-0wezrr1bA pandemic warning?
cord-290548-0wezrr1btitle: Villains or heroes?
cord-319658-u0wjgw50Cellular hijacking: a common strategy for microbial infection Diet, microbiota and autoimmune diseases Integration of Innate Immune Signaling Self or non- self?
cord-313301-7mkadtp9Recurrent mutations associated with isolation and passage of SARS coronavirus in cells from non- human primates Mechanisms of avian retrovial host range extension Deletion mutations of the genome segments of wound tumor virus Speciation via habitat selection: the evolution of reproductive isolation as a correlated character Laboratory experiments on speciation: what have we learned in 40 years?
cord-345157-fhmhpobiWho regulates whom?
cord-351490-2fx0w30uToward the extinction of phenotypes?
cord-005281-wy0zk9p8CRISPR/ Cas systems Cpf1 is a single RNA- guided endonuclease of a class 2 CRISPR- Cas system How many antiviral small interfering RNAs may be encoded by the mammalian genomes?
cord-005281-wy0zk9p8Can viruses make us human?
cord-005281-wy0zk9p8The next genetics revolution?
cord-262585-5vjqrnwhFor example, can some viral peptides be useful as adjuvants?
cord-262585-5vjqrnwhWhat specific constraints limit SLiM evolvability?
cord-262585-5vjqrnwhin the design of vaccines and therapies to promote global health?
cord-319448-gt6uqfrlThe recognition that the disease- to- infection ratio for West Nile virus in endemic areas is very low, led to the successful experimental use of passive antibody therapy with immunoglobulins from asymptomatic Introduces the'damage- response'framework and proposes a new classification for pathogens based on their ability to damage the host as a function of the host response Expands the'damage- response'framework to incorporate the variable of time and proposes that the outcome of the host- microorganism interaction can be reduced to four states that differ in the amount of damage incurred by the host as a function of time What is a pathogen?
cord-319448-gt6uqfrlbreath- taking progress Saccharomyces cerevisiae bacteremia A Saccharomyces cerevisiae mutant with increased virulence Parasitealtered behaviour: is the effect of Toxoplasma gondii on Rattus norvegicus specific?
cord-276585-m1dkkbq7: West Nile virus spread to Galapagos Quantitative risk assessment of the pathways by which West Nile virus could reach Hawaii Processive proofreading by the adenovirus DNA polymerase- association with the priming protein reduces exonucleolytic degradation Hybridization as a source of variation for adaptation to new environments Structure of SARS coronavirus spike receptor- binding domain complexed with receptor Infectious disease dynamics: what characterizes a successful invader?
cord-276585-m1dkkbq7: what are the relative roles of ecology and evolution?
cord-276585-m1dkkbq7The origins of acquired immune deficiency syndrome viruses: where and when?
cord-299828-fb84rtmxA BLACK BOX?
cord-299828-fb84rtmxRana muscosa Sociality, density- dependence and microclimates determine the persistence of populations suffering from a novel fungal disease, white- nose syndrome Should we expect population thresholds for wildlife disease?
cord-299828-fb84rtmxWhat are the future directions for WDM?
cord-031937-qhlatg84Clostridium difficile: an under- recognized cause of reactive arthritis?
cord-031937-qhlatg84how do classical and non- classical HLA alleles modulate immune response to human immunodeficiency virus and hepatitis C virus infections?
cord-335774-15fhg8o9Vector- Borne Zoonotic Dis Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents Short report: Phylogenetically distinct hantaviruses in the masked shrew( Sorex cinereus) and dusky shrew( Sorex monticolus) in the United States Isolation and characterization of a hantavirus from lemmus sibiricus: Evidence for host switch during hantavirus evolution Complete genome sequences of Monongahela hantavirus from Pennsylvania Genetic diversity and distribution of Peromyscus- borne hantaviruses in North America Two cases of hantavirus pulmonary syndrome in Randolph county, West Virginia: A coincidence of time and place?
cord-335774-15fhg8o9Vector- Borne Zoonotic Dis The velocity of climate change Prairie conservation in North America Perspectives on grassland conservation efforts: Should we rewild to the past or conserve for the future?
cord-355239-fc52dn3vInactivation of the flagellin gene of Salmonella enterica serotype enteritidis strongly reduces invasion into differentiated Caco-2 cells Active invasion and/or encapsulation?
cord-269975-1ebmq7t8Is in vitro antibiotic combination more effective than single- drug therapy against anthrax?
cord-255181-du6rqc6i-a threat under control?
cord-255181-du6rqc6iWet markets-a continuing source of severe acute respiratory syndrome and influenza?
cord-262434-q4tk96tq: Are bats special?
cord-262434-q4tk96tqWhat?
cord-262434-q4tk96tqlyssavirus emergence and perpetuation Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes A distinct lineage of influenza A virus from bats Mass extinctions, biodiversity and mitochondrial function: Are bats"special"as reservoirs for emerging viruses?
cord-312545-io2jmp7oHeterakis gallinarum in the ring- necked pheasant and the grey partridge Is a healthy ecosystem one that is rich in parasites?
cord-312545-io2jmp7oHow should pathogen transmission be modelled?
cord-312545-io2jmp7oReunion Island A case of autochthonous Plasmodium vivax malaria West Nile virus: a growing concern?
cord-309642-wwaa6ls0Some aspects of pulmonary defence Retroviral transforming genes in normal cells?
cord-309642-wwaa6ls0The immunopathogenesis of dengue haemorrhagic fever Virally induced alterations in cellular permeability: A basis of cellular and physiological damage?
cord-297960-4x1j0iqg: can we ever expect the unexpected?
cord-297960-4x1j0iqgHow Do intrinsically disordered viral proteins hijack the cell?
cord-355024-v5lahyw4The Washington experience Where and why are 10 million children dying every year?
cord-355024-v5lahyw4mistaken or maligned?
cord-000546-0hobwqpe1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen Genomic RNAi screening in Drosophila S2 cells: what have we learned about host- pathogen interactions?
cord-000546-0hobwqpehow do LF and EF, with such seemingly disparate enzymatic activities, collaborate during infection( particularly within vascular endothelial cells, which become leaky at advanced stages of disease, leading to death)?
cord-000546-0hobwqpemechanisms and relationship to cancer susceptibility Role for lysosomal enzyme beta- hexosaminidase in the control of mycobacteria infection Ablation of Drosophila photoreceptor cells by conditional expression of a toxin gene Nimrod, a putative phagocytosis receptor with EGF repeats in Drosophila plasmatocytes Sequence homology and structural analysis of the clostridial neurotoxins Virulence studies of Scedosporium and Fusarium species in Drosophila melanogaster Does preexposure of Aspergillus fumigatus to voriconazole or posaconazole in vitro affect its virulence and the in vivo activity of subsequent posaconazole or voriconazole, respectively?
cord-324697-c0dv1zmiDespite the further mapping of the SOX targeting element and assessment of secondary structure participation one outstanding question remained: what is the direct impact of these RNA features in target recognition?
cord-324697-c0dv1zmiMore specifically, how do these features influence SOX affinity and/or the efficiency by which targets are degraded?
cord-001714-jfawhnsq-Little studied so far-Source population: any population that transmits infection directly to the target population[ 10]-Red deer and domestic pigs for bovine tuberculosis in New Zealand[ 12]?
cord-001714-jfawhnsq: Can We Anticipate Emerging Infectious Diseases in Their Hotspots?
cord-001714-jfawhnsq: what do our diagnostic results mean?
cord-001714-jfawhnsqIdentifying reservoirs of infection: a conceptual and practical challenge When is a reservoir not a reservoir?
cord-001714-jfawhnsqUnderstanding pathogen transmission dynamics in waterbird communities: at what scale should interactions be studied?
cord-289443-46w52de3TLR4/ MD-2 Signatures of positive selection in Toll- like receptor( TLR) genes in mammals Mass extinctions, biodiversity and mitochondrial function: are bats'special'as reservoirs for emerging viruses?
cord-289443-46w52de3The Causes of Evolution( Longmans, Green,& Co,1932) Revenge of the phages: defeating bacterial defences Genomic variability as a driver of plant- pathogen coevolution?
cord-289443-46w52de3The dashed arrows and'?'indicate steps that lack clear molecular definition or are only inferred.
cord-289443-46w52de3Why then is human TRIM5 so highly inefficient against HIV-1?
cord-348819-gq7lp931Could ecologists be more random?
cord-348819-gq7lp931Microbiol Onward transmission of viruses: how do viruses emerge to cause epidemics after spillover?
cord-348819-gq7lp931Straightforward alternatives to haphazard spatial sampling What is stirring in the reservoir?
cord-261466-b9r4cyp7A review of the clinical presentation of dientamoebiasis Transmission of Dientamoeba fragilis: pinworm or cysts?
cord-261466-b9r4cyp7The lack of precise epidemiological data is indicated by'?'.
cord-261466-b9r4cyp7What is the importance of zoonotic trichomonads for human health?
cord-261466-b9r4cyp7isolate from a whitewinged pigeon extremely closely related to isolates of T. vaginalis represent a case of human to bird transfer( accession HM016231 in Figure 2)?
cord-018555-3lta1tbpIn an evolutionary context, which is where the concept of adaptation lies, why would a symbiont switch to being pathogenic, either at some stage in its life cycle or in some hosts at the same stage but not in others?
cord-018555-3lta1tbpThe question arises,"Is becoming a pathogen an adaptation for a symbiont?"
cord-018555-3lta1tbpWhat if transmission occurs not so much from living infected hosts but from hosts after they die?
cord-014397-7b88ycv8A sialoglycopeptide from human erythrocytes with receptor- like properties for encephalomyocarditis and influenza viruses Resistance in transgenic tobacco plants expressing a nonstructural gene sequence of tobacco mosaic virus is a consequence of markedly reduced virus replication Does the beta- andrenergic factor receptor function as reovirus receptor?
cord-014397-7b88ycv8Determinants essential for the transmissible gastroenteritis virus receptor interaction reside within a domain of aminopeptidase N that is distinct from the enzymatic site Molecular characterization of gene- for- gene systems in plant fungus interactions and the application of avirulence genes in control of plant pathogens Risk assessment: do we let history repeat itself?
cord-014397-7b88ycv8Plant viral resistance Will transgenic crops generate new viruses and new diseases?
cord-014397-7b88ycv8The mammalian cell- virus relationship Attachment of poliovirus to cultivated cells of primate and nonprimate origin Cellular receptor for poliovirus: molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily Binding to sialic acids is not an essential step for entry of animal rotaviruses to epithelial cells in culture Genetic exchange between bacteriophage T4 and filamentous fungi?
cord-014397-7b88ycv8Why did certain mechanisms develop and others not?
cord-003806-ctass7hzA question motivating this analysis was one step deeper in the complexity of these effects: does the self- limiting effect of adaptive immunity worsen when revertant is present?
cord-003806-ctass7hzEvolutionary reversion of live viral vaccines: Can genetic engineering subdue it?
cord-003806-ctass7hzFollowing Yellow Fever Vaccination?
cord-329149-1giy1fowA secreted protein microarray platform for extracellular protein interaction discovery Viral mimicry of cytokines, chemokines and their receptors Pathogen- derived immunomodulatory molecules: future immunotherapeutics?
cord-329149-1giy1fowHow do pathogens drive the evolution of paired receptors?
cord-329149-1giy1fowHow many drug targets are there?
cord-329149-1giy1fowWhat have RNAi screens taught us about viral- host interactions?
cord-270604-u62437dhAncient co- speciation of simian foamy viruses and primates Ancient origin and molecular features of the novel human T- lymphotropic virus type 3 revealed by complete genome analysis Risk factors for human disease emergence Small steps or giant leaps for male- killers?
cord-270604-u62437dhThe matrix protein gene sequence analysis reveals close relationship between peste des petits ruminants virus( PPRV) and dolphin morbillivirus Canine distemper virus- a morbillivirus in search of new hosts?
cord-270604-u62437dhWhen do parasites fail to speciate in response to host speciation?
cord-307803-rlvk6bcxHow old are the major human pathogens?
cord-307803-rlvk6bcxWhat are pathogens, and what have they done to and for us?
cord-307803-rlvk6bcxWhat is the host range of pathogens?
cord-307803-rlvk6bcxWhere are the resistance- conferring genes in the human genome?
cord-021465-2pj26fmvThe chicken MHC complex Common antigenicity of avian reoviruses Is the gene pool of influenza viruses in shorebirds and gulls different from that in wild ducks?
cord-021465-2pj26fmvThe ecology of influenza viruses in ducks and analysis of influenza viruses with monoclonal antibodies Are seals frequently infected with avian influenza viruses?
cord-021465-2pj26fmvThe viruses of the future?
cord-021465-2pj26fmvThis may be true under truly"natural"conditions; but what happens under human- dictated conditions such as vaccination and by defining the host population through breeding and housing?
cord-021465-2pj26fmvWhat viruses other than the orthomyxoviruses may someday establish a similar relationship where transmission to a mammalian intermediate or even direct transmission may allow introduction into the human population?
cord-104317-t30dg6oj: next- generation sequencing applied to phage populations in the human gut GB Virus C/ Hepatitis G Virus Infection: A Favorable Prognostic Factor in Human Immunodeficiency Virus- Infected Patients?
cord-104317-t30dg6ojCulture An inquiry into the causes and effects of the variolae vaccinae, a disease discovered in some of the western counties of England, particularly Gloucestershire, and known by the name of the cow pox Coevolution of hosts and parasites Vertical transmission of viruses What is a quasispecies?
cord-104317-t30dg6ojPhage Therapy in the Food Industry Complete nucleotide sequences of four dsRNAs associated with a new chrysovirus infecting Aspergillus fumigatus Mycoviruses: future therapeutic agents of invasive fungal infections in humans?
cord-104317-t30dg6ojPositional cloning of the mouse retrovirus restriction gene Fv1 Rmcf2, a xenotropic provirus in the Asian mouse species Mus castaneus, blocks infection by polytropic mouse gammaretroviruses From ancestral infectious retroviruses to bona fide cellular genes: Role of the captured syncytins in placentation Retroviruses and the Placenta Retroviral gene therapy: safety issues and possible solutions Decade- Long Safety and Function of Retroviral- Modified Chimeric Antigen Receptor T Cells Bacteriophage adhering to mucus provide a non- host- derived immunity Reinventing phage therapy: are the parts greater than the sum?
cord-104317-t30dg6ojPublic Health and Medical Uncertainty Current and emerging infectious risks of blood transfusions AIDS pathogenesis: what have two decades of HIV research taught us?
cord-104317-t30dg6ojWhile the virus has a safe home during persistence, the question arises that if a virus is not replicating, or is present at very low levels, how is it transmitted to the next host?
cord-291946-kq0rsuxj: Can we ever expect the unexpected?
cord-291946-kq0rsuxjBut where do they come from?
cord-291946-kq0rsuxjHow then did this mammalian retrovirus get into birds?
cord-291946-kq0rsuxjThus, the answer to the question''where did these viruses come from?''will increasingly become''they came from ancient forms of other viruses,''although in some cases, such as those described for REV[ 21], they come through a thoroughly circuitous route.
cord-291946-kq0rsuxjUltimately, though, where did these viruses come from?
cord-269505-7g8lio9lBut does reducing diversity itself increase transmission, or is increased transmission the consequence of the removal of particular species?
cord-269505-7g8lio9lBut what role, if any, does biodiversity have in the processes by which new pathogens emerge?
cord-269505-7g8lio9lCould changes in biodiversity within the bodies of organisms also alter pathogen transmission?
cord-269505-7g8lio9lHow many hosts?
cord-269505-7g8lio9lNew UN science body to monitor biosphere Ecosystem Functioning, and Human Wellbeing: an Ecological and Economic Perspective Ecosystems and Human Well- Being: Current State and Trends: Findings of the Condition and Trends Working Group Red List of Threatened Species Version and Beyond: Rising to the Biodiversity Challenge Homage to Linnaeus: How many parasites?
cord-269505-7g8lio9lVector- Borne Zoonotic Dis Has the introduction of brown trout altered disease patterns in native New Zealand fish?
cord-270803-jtv5jmknMass extinctions, biodiversity and mitochondrial function: are bats ‘ special ’ as reservoirs for emerging viruses?
cord-270803-jtv5jmknOlival KJ, Epstein JH, Wang L- F, Field HE, Daszak P: Are bats unique virus reservoirs?
cord-270803-jtv5jmknPurely a numbers game: more bat species= more viruses?
cord-270803-jtv5jmknSo the question ‘ Are bats different, special or exceptional? ’
cord-270803-jtv5jmknSo the question'Are bats different, special or exceptional?'has become a focal point in the field of virology, bat biology and virus- host co- evolution.
cord-270803-jtv5jmknThe most recent paper out of a series studies on astroviruses conducted by the Hong Kong group, which demonstrated that the genetic diversity of astroviruses in bats is greater than those in other mammals Evolutionary insights into the ecology of coronaviruses Emergence and persistence of hantaviruses Virus evolution and genetic diversity of hantaviruses and their rodent hosts Evolution of the Old World Arenaviridae and their rodent hosts: generalised host- transfer or association by descent?
cord-270803-jtv5jmknThe question'Are bats different?'has been raised at many international conferences and has been the topic of several previous reviews[ 1, 2,20,23].
cord-270803-jtv5jmknthey linked?
cord-345654-vyz6f3heCan we rule out that a dedicated research effort with sufficient funds and expertise could produce a highly virulent and transmissible synthetic virus?
cord-345654-vyz6f3heCulicoides and the emergence of bluetongue virus in northern Europe Incriminating bluetongue virus vectors with climate envelope models Why did bluetongue spread the way it did?
cord-345654-vyz6f3heThe evolution of host specialization: are trade- offs overrated?
cord-345654-vyz6f3heThe experimental evolution of specialists, generalists, and the maintenance of diversity Arbovirus evolution in vivo is constrained by host alternation Trade- offs in host range evolution of plant viruses Emerging viruses: why they are not jacks of all trades?
cord-345654-vyz6f3heWhy do RNA viruses recombine?
cord-345654-vyz6f3heWhy do bacteria engage in homologous recombination?
cord-290253-hxxizipkAcross 95 Drosophila Species Upper thermal limits of Drosophila are linked to species distributions and strongly constrained phylogenetically Upper thermal limits in terrestrial ectotherms: how constrained are they?
cord-290253-hxxizipkAre extreme temperatures a stress?
cord-290253-hxxizipkHow will global climate change affect parasite- host assemblages?
cord-290253-hxxizipkThe role of genotype- by- environment interactions in sexual selection How will global climate change affect parasite- host assemblages?
cord-290253-hxxizipkThe thermal mismatch hypothesis explains host susceptibility to an emerging infectious disease Genotype- environment interaction and the evolution of phenotypic plasticity Quantitative Genetics and the Evolution of Reaction Norms Genotype- by- environment interactions and adaptation to local temperature affect immunity and fecundity in Drosophila melanogaster Coexistence of Similar Genotypes of Daphnia magna in Intermittent Populations: Response to Thermal Stress Temperature checks the Red Queen?
cord-290253-hxxizipkUsing a controlled method of viral inoculation allows us to standardize inoculation dose so we can ask, given equal exposure, how does temperature affect the ability of a pathogen to persist and replicate in a given host?
cord-290253-hxxizipkthe key to understanding host- pathogen interactions and microbial pest control?
cord-305327-hayhbs5uAre we prepared for the worst of these hypothetic pandemics abundantly illustrated in the cinema and unfortunately sometimes overwhelmed when reality goes beyond fiction?
cord-305327-hayhbs5uAre we prepared for the worst?
cord-305327-hayhbs5uDid we learn from the past epidemics?
cord-305327-hayhbs5uLet us first honestly address the fundamental questions about epdimeics and preparedness: What did we learn from all the past epidemics, what will we remember in times of need?
cord-305327-hayhbs5uPerhaps, in a shrinking global community, after too many Ebola virus disease outbreaks, we will learn and be prepared for future epidemic challenges?
cord-305327-hayhbs5uThe Rockefeller Foundation From the Ebola river to the Ebola virus disease pandemic: what have we learned?
cord-305327-hayhbs5uThe smallpox pandemic of Smallpox: 12,000 years from plagues to eradication: a dermatologic ailment shaping the face of society Strategies for mitigating an influenza pandemic Dengue, urbanization and globalization: the unholy trinity of the 21st century SARS: an emerging global microbial threat Predicting epidemic risk from past temporal contact data Ebola control: effect of asymptomatic infection and acquired immunity Shedding of Ebola virus in an asymptomatic pregnant woman Understanding the emergence of Ebola virus disease in sierra leone: stalking the virus in the threatening wake of emergence Perspectives on West Africa Ebola virus disease outbreak Aedes alpobictus and the world trade in used tires, 1988- 1995: the shape of things to come?
cord-018425-vyiuv5quBiogeography of parasitic nematode communities in the Galápagos giant tortoise: implications for conservation management Do island populations have less genetic variation than mainland populations?
cord-018425-vyiuv5quFor reasons already mentioned, it is difficult to determine the order and combination of arrival in Galapagos: did colonizing birds arrive infected with flies and Haemoproteus?
cord-018425-vyiuv5quOr did the flies and Haemoproteus arrive later?
cord-018425-vyiuv5quPlatygastroidea: Scelionidae) and description of three new species Are there differences in immune function between continental and insular birds?
cord-018425-vyiuv5quPredicting pathogen introduction: West Nile virus spread in Galápagos Coevolution: a history of the macroevolutionary approach to studying hostparasite associations Experimental demonstration of the fitness consequences of an introduced parasite of Darwin's finches Epidemiology of heartworm: what is happening in South America and Mexico?
cord-018425-vyiuv5quSphenicus mendiculus Transhemispheric exchange of Lyme disease spirochetes by seabirds Global patterns of influenza a virus in wild birds 110 years of Avipoxvirus in the Galapagos Islands Conservation medicine on the Galápagos Islands: partnerships among behavioural, population, and veterinary scientists How frequently do avian lice miss the boat?
cord-018425-vyiuv5quThe global spread of parasites: what do Hawaiian streams tell us?
cord-018425-vyiuv5quThe theory of island biogeography Parasites lost- do invaders miss the boat or drown on arrival?
cord-349975-quw1gyw7Desiccation risk drives the spatial ecology of an invasive anuran( Rhinella marina) in the Australian semi- desert Rhabdias pseudosphaerocephala infection in Bufo marinus: lung nematodes reduce viability of metamorph cane toads Parasites and pathogens lag behind their host during periods of host range advance Survival of the feces: does a nematode lungworm adaptively manipulate the behavior of its cane toad host?
cord-349975-quw1gyw7Extensive transmission of Mycobacterium tuberculosis from a child Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly- parasitism?
cord-349975-quw1gyw7How do viruses control mitochondriamediated apoptosis?
cord-349975-quw1gyw7Malaria tolerance À for whom the cell tolls?
cord-349975-quw1gyw7Origin of the parasites of an invading species, the Australian cane toad( Bufo marinus): are the lungworms Australian or American?
cord-349975-quw1gyw7The social epidemiology of human immunodeficiency virus/ acquired immunodeficiency syndrome Host heterozygosity and genotype rarity affect viral dynamics in an avian subspecies complex Who infects whom?
cord-349975-quw1gyw7an ecological and evolutionary overview Role of disease- associated tolerance in infectious superspreaders Reproductive and immune system interactions in the context of life history and sexual selection theory Are migratory animals superspreaders of infection?
cord-349975-quw1gyw7vicious circles?
cord-017819-85x0juiwAre they indicators of ecosystem health?
cord-017819-85x0juiwBut do we really need the conservation of parasitic species?
cord-017819-85x0juiwDifferential species- specific ectoparasitic mite intensities in two intimately coexisting sibling bat species: Resource- mediated host attractiveness or parasite specialization?
cord-017819-85x0juiwDoes clutch size evolve in response to parasites and immunocompetence?
cord-017819-85x0juiwDoes inbreeding and loss of genetic diversity decrease disease resistance?
cord-017819-85x0juiwFaster evolutionary rates in endosymbiotic bacteria than in cospeciating insect hosts Is parasitism a missing ingredient in model ecosystems?
cord-017819-85x0juiwHowever, do you ever see a child squeezing a stuffed worm, flea or tick?
cord-017819-85x0juiwMany roles at many levels?
cord-017819-85x0juiwThe former distribution and decline of the thylacine Heritable true fitness and bright birds: A role for parasites?
cord-017819-85x0juiwWhat could be the consequences of maintaining hosts during many generations in a parasite- free environment?
cord-017819-85x0juiwWhat is the Allee effect?
cord-018821-e9oxvgar( Pteropus spp Ecological dynamics of emerging bat virus spillover Highly structured fission- fusion societies in an aerial- hawking carnivorous bat Is parasite load dependent on host aggregation size?
cord-018821-e9oxvgarA comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
cord-018821-e9oxvgarBat white- nose syndrome: an emerging fungal pathogen?
cord-018821-e9oxvgarContact networks and transmission of an intestinal pathogen in bumble bee( Bombus impatiens) colonies Do social networks of female northern long- eared bats vary with reproductive period and age?
cord-018821-e9oxvgarDoes the mode of transmission between hosts affect the host choice strategies of parasites?
cord-018821-e9oxvgarFrequent arousal from hibernation linked to severity of infection and mortality in bats with white- nose syndrome Applying network analysis to the conservation of habitat trees in urban environments: a case study from Do animals living in larger groups experience greater parasitism?
cord-018821-e9oxvgarHost sex and ectoparasite choice: preference for, and higher survival on female hosts Parasitism and group size in social animals: a meta- analysis Network models: an underutilized tool in wildlife epidemiology?
cord-018821-e9oxvgarHow should pathogen transmission be modelled?
cord-018821-e9oxvgarHuddling reduces evaporative water loss in torpid Natterer's bats, Myotis nattereri Could localized warm areas inside cold caves reduce mortality of hibernating bats affected by white- nose syndrome?
cord-018821-e9oxvgarMy home is your castle: roost making is sexually selected in the bat Lophostoma silvicolum Who infects whom?
cord-018821-e9oxvgarassociated factors and effect on group stability Parasite species richness in carnivores: effects of host body mass, latitude, geographical range and population density Superspreading and the effect of individual variation on disease emergence Social barriers to pathogen transmission in wild animal populations Experimental infection of bats with Geomyces destructans causes white- nose syndrome Can mite parasitism affect the condition of bat hosts?
cord-348841-qxkmngyk: Where are we now?
cord-348841-qxkmngykA framework for comparing viral phylogenies and environmental landscape data Landscape- genetic analysis of population structure in the Texas gray fox oral rabies vaccination zone Going through the motions: Incorporating movement analyses into disease research Nonstationary patterns of isolation- by- distance: inferring measures of local genetic differentiation with Bayesian kriging Is there such a thing as landscape genetics?
cord-348841-qxkmngykCombining landscape ecology and population genetics Host dispersal as the driver of parasite genetic structure: A paradigm lost?
cord-348841-qxkmngykDoes inbreeding and loss of genetic diversity decrease disease resistance?
cord-348841-qxkmngykHow's the flu getting through?
cord-348841-qxkmngykThe early spread and epidemic ignition of HIV-1 in human populations Simultaneously reconstructing viral cross- species transmission history and identifying the underlying constraints Urban landscapes can change virus gene flow and evolution in a fragmentationsensitive carnivore Linking social and spatial networks to viral community phylogenetics reveals subtype- specific transmission dynamics in African lions Towards an eco- phylogenetic framework for infectious disease ecology Clustering and assignment methods in landscape genetics Using spatial Bayesian methods to determine the genetic structure of a continuously distributed population: Clusters or isolation by distance?
cord-348841-qxkmngykThe role of landscape barriers and sex- biased dispersal Infectious disease transmission and contact networks in wildlife and livestock Network models: An underutilized tool in wildlife epidemiology?
cord-348841-qxkmngykWhen is connectivity important?
cord-348841-qxkmngykapplications Current status, future opportunities, and remaining challenges in landscape genetics Identifying future research needs in landscape genetics: Where to from here?
cord-276637-re9c3e0b, the vector of Lyme disease Has early ice clearance increased predation on breeding birds by polar bears?
cord-276637-re9c3e0b: why should we care?
cord-276637-re9c3e0bAvian host spectrum of avipoxviruses Population trends in Kittiwake Rissa tridactyla colonies in relation to tick infestation Measuring aggregation of parasites at different host population levels Migration, prospecting, dispersal?
cord-276637-re9c3e0bDo blood parasites infect Magellanic penguins( Spheniscus magellanicus) in the wild?
cord-276637-re9c3e0bFeather mites on birds: costs of parasitism or conditional outcomes?
cord-276637-re9c3e0bFirst detection of avian influenza virus( H4N7) in Giant petrel monitored by geolocators in the Antarctic region Avian cholera, a threat to the viability of an Arctic seabird colony?
cord-276637-re9c3e0bHow will global climate change affect parasite- host assemblages?
cord-276637-re9c3e0bSymbiotic feather mites synchronize dispersal and population growth with host sociality and migratory disposition Feather mites on group- living red- billed choughs: a non- parasitic interaction?
cord-276637-re9c3e0bThese baseline studies are essential for documenting the effect of shifting environmental conditions on bird- parasite relationships and teasing apart the questions'is this new?'
cord-276637-re9c3e0bUria aalge in the Baltic sea Survey for Haemoproteus, Trichomonas gallinae, Chlamydophila psittaci, and Salmonella in Galapagos Islands columbiformes Phylogeny of"philoceanus complex"seabird lice( Phthiraptera: Ischnocera) inferred from mitochondrial DNA sequences Potential impacts of climate change on infectious diseases in the Arctic Occurrence of blood parasites in seabirds admitted for rehabilitation in the Western Cape Parasites, petrels and penguins: does louse presence reflect seabird phylogeny?
cord-276637-re9c3e0bWhat host movement matters for infectious agent circulation?
cord-276637-re9c3e0bnesting in Slovakia, central Europe Are Microbes the Source of a Seabird's Tangerine- Like Scent?
cord-276637-re9c3e0bor'new to us?'
cord-019068-6j42euvcAre little hosts dead- ends or'bait'?
cord-019068-6j42euvcCan all these juveniles be'wasted'in dead- end hosts?
cord-019068-6j42euvcDescriptions of caligiform copepods in plankton samples collected from East Asia: accidental occurrences or a new mode of life cycle?
cord-019068-6j42euvcIf juveniles react this way to attack, and adults are known to switch hosts, why would juveniles in a prey host not transfer to a predator?
cord-019068-6j42euvcIs parasitism rated as a proportion of good vs evil?
cord-019068-6j42euvcIs this a desperate survival mechanism or something more?
cord-019068-6j42euvcIs this because the blood- swollen ones are more easily found?
cord-019068-6j42euvcOr is this due to preference by cleaners for fish blood rather than gnats without blood?
cord-019068-6j42euvcThese include the following: how can little, slow, juvenile fish isopods( cymothoids) possibly chase and infect fast- swimming pelagic fishes?
cord-019068-6j42euvcWe do not understand how they can be called parasites?
cord-019068-6j42euvcWhat's love got to do with it?
cord-019068-6j42euvcWhy do juvenile isopods infect and develop into non- swimming forms in the mouths of fishes too small for them to develop into adults?
cord-296179-hobh6akqBest of both worlds?
cord-296179-hobh6akqBut, how exactly does genetic diversity reduce disease spread?
cord-296179-hobh6akqBut, is increased susceptibility directly due to reduced diversity, or does inbreeding depression have an effect by compromising host condition?
cord-296179-hobh6akqDoes inbreeding and loss of genetic diversity decrease disease resistance?
cord-296179-hobh6akqHOW MUCH DIVERSITY IS NECESSARY?
cord-296179-hobh6akqHowever, a practical question arises: would the beneficial effect of adding hosts with novel genotypes, in order to increase local genetic diversity, outweigh the positive effect of increasing population size on R 0?
cord-296179-hobh6akqHowever, several questions remain:( 1) Does a diversity threshold exist?
cord-296179-hobh6akqIn other words, can parasites be eliminated by increasing host genetic diversity above some threshold value?
cord-296179-hobh6akqThe costs and benefits of genetic heterogeneity in resistance against parasites in social insects Disease ecology in the Galapagos hawk( Buteo galapagoensis): host genetic diversity, parasite load, and natural antibodies Dioecy, hermaphrodites and pathogen load in plants How do pathogen evolution and host heterogeneity interact in disease emergence?
cord-296179-hobh6akqWhat are the effects of genetic diversity in the parasite population versus that of the host population?
cord-296179-hobh6akqWhat are the relative effects of host density and host genetic diversity on disease spread?
cord-296179-hobh6akqWhat is the heritability of parasite resistance in natural populations?
cord-296179-hobh6akqkey: cord-296179-hobh6akq authors: King, K C; Lively, C M title: Does genetic diversity limit disease spread in natural host populations?
cord-277417-f71jwdzjA meta- analysis of trends in prognostic markers of HIV disease progression and transmission Association between the rate of CD4+ T cell decrease and the year of human immunodeficeny virus( HIV) type 1 seroconversion among persons enrolled in the Swiss HIV cohort study Is HIV-1 evolving to a less virulent form in humans?
cord-277417-f71jwdzjA phylogenomic analysis of Marek's disease virus reveals independent paths to virulence in Eurasia and North America Immunity promotes virulence evolution in a malaria model Has the rate of progression to AIDS changed in recent years?
cord-277417-f71jwdzjCan Ebola virus evolve to be less virulent in humans?
cord-277417-f71jwdzjCan we read the future from a tree?
cord-277417-f71jwdzjConvergent evolution of lysozyme sequences?
cord-277417-f71jwdzjDid Zika virus mutate to cause severe outbreaks?
cord-277417-f71jwdzjGlobalization, land use, and the invasion of West Nile virus H5N1 influenza: a protean pandemic threat Are we ready for pandemic influenza?
cord-277417-f71jwdzjIs there any consistent association between host- jumping and virulence such that predictions can be made about how virulence might evolve following emergence?
cord-277417-f71jwdzjThe human immunodeficiency virus Italian seroconversion study Is the virulence of HIV changing?
cord-277417-f71jwdzjThis paper provides an overview of the theory that there is a trade- off between virulence and transmissibility, highlighting areas in which the theory has been challenged and extended over the past 20 years Adaptive virulence evolution: the good old fitness- based approach Virulence and transmissibility of pathogens: what is the relationship?
cord-277417-f71jwdzjVirological factors that increase the transmissibility of emerging human viruses Coevolution of hosts and parasites Evolution in Health and Disease Challenging the trade- off model for the evolution of virulence: is virulence management feasible?
cord-277417-f71jwdzjWhat level of virulence is optimized by natural selection and why?
cord-277417-f71jwdzjWhy do RNA viruses recombine?
cord-277417-f71jwdzjWill a virus become more or less virulent in a new host?
cord-277417-f71jwdzjwhy they are not jacks of all trades?
cord-017008-c7skxte0: what is the relationship?
cord-017008-c7skxte0And more importantly, what was the rate of transmission between hosts?
cord-017008-c7skxte0Both ecological and functional perspectives on host- pathogens ’ interactions are required to answer the opening question but also to devise appropriate health- care measures in order to prevent( and predict?)
cord-017008-c7skxte0But what aspects of his work exactly are evolutionary or Darwinian?
cord-017008-c7skxte0Despite the( crucial) facts that antibiotics were available during the second two pandemics, and that medical care had signifi cantly improved and was more effi cient after 1950, this raises the question: why was the 1918- 19 pandemic so deadly to humans?
cord-017008-c7skxte0Did the 1918- 19 infl uenza pandemic originate in China?
cord-017008-c7skxte0Enhanced virulence of infl uenza A viruses with the haemagglutinin of the 1918 pandemic virus?
cord-017008-c7skxte0For instance, how close were the troops?
cord-017008-c7skxte0How likely is it that this genetic information be used for harmful purposes?
cord-017008-c7skxte0How many soldiers were there?
cord-017008-c7skxte0In sum, both ecological and functional perspectives on host- pathogens'interactions are required to answer the opening question of this essay but also to devise appropriate health- care measures in order to prevent( and predict?)
cord-017008-c7skxte0In: The threat of pandemic infl uenza: are we ready?
cord-017008-c7skxte0Is Mayr's proximate- ultimate dichotomy still useful?
cord-017008-c7skxte0Should n't host and pathogens 2 peacefully coevolve, and thus maximize both their chances of survival, instead of engaging in a near- infi nite arms race?
cord-017008-c7skxte0So why was the Spanish infl uenza so devastating?
cord-017008-c7skxte0The question"why do parasites harm their hosts?"is recurrent in evolutionary biology and ecology, and has several implications for the medical sciences, particularly public health and epidemiology.
cord-017008-c7skxte0What if someone with nefarious intentions reconstructs the virus?
cord-017008-c7skxte0What if, by accident or not, the virus escapes into the environment?
cord-017008-c7skxte0What is a pathogen?
cord-017008-c7skxte0Why do parasites harm their hosts?
cord-017008-c7skxte0“ Why do parasites harm their host? ” is a recurrent question in evolutionary biology and ecology, and has several implications for the biomedical sciences, particularly public health and epidemiology.
cord-353609-no3mbg5dA virus reveals population structure and recent demographic history of its carnivore host Parasites: Proxies for host genealogy and ecology?
cord-353609-no3mbg5dAnd how might co- infections with these undiscovered viruses influence the dynamics of the more well known viruses?
cord-353609-no3mbg5dAnd what are the relative roles of genetic relatedness and contact rate for transmission?
cord-353609-no3mbg5dAnd what are the relative roles of genetic relatedness and contact rate for transmission?
cord-353609-no3mbg5dAre we in the midst of the sixth mass extinction?
cord-353609-no3mbg5dAs such, wild populations of rodents can be valuable as model disease systems to address relevant questions like: Are there key hosts for transmission?
cord-353609-no3mbg5dAs technology becomes more affordable, and thus accessible, there will be increasing opportunities to ask large- scale questions such as: How does the virosphere vary across space and time?
cord-353609-no3mbg5dCan we use this to define risk of cross- species transmission or to inform conservation efforts?
cord-353609-no3mbg5dCould parasites destabilize mouse populations?
cord-353609-no3mbg5dFor instance, what characteristics of hosts and viruses make them more or less likely to be involved in cross- species transmission?
cord-353609-no3mbg5dHow do these pathogens flow through populations?
cord-353609-no3mbg5dHow does it vary across species?
cord-353609-no3mbg5dHow does prevalence vary seasonally or over time?
cord-353609-no3mbg5dHow many species?
cord-353609-no3mbg5dPending questions include: Which geographic areas will experience more disease and conservation problems?
cord-353609-no3mbg5dThe peopling of the Pacific from a bacterial perspective Distinguishing human ethnic groups by means of sequences from Heliclobacter pylori: Lessons from Ladakh A parasite reveals cryptic phylogeographic history of its host Are lice good proxies for host history?
cord-353609-no3mbg5dWhat characteristics of hosts and viruses make them more or less likely to be involved in cross- species transmission events?
cord-353609-no3mbg5dWhat is the contact rate between the reservoir and humans?
cord-353609-no3mbg5dWhich areas pose the highest risk for pandemic spread of pathogens?
cord-298475-3bhiattkAn introduction to qualitative research Are we there yet?
cord-298475-3bhiattkAny long- term threats or even opportunities emerging from this situation?
cord-298475-3bhiattkDid you receive any support from the government as a result of the pandemic?
cord-298475-3bhiattkDo you plan to move to a long- term rental mode?
cord-298475-3bhiattkHas Covid-19 disrupted the disrupter?
cord-298475-3bhiattkHave the platforms( e.g. Airbnb) been supportive in terms of the impacts hosts have incurred as a result of the pandemic?
cord-298475-3bhiattkHave you received any requests or enquiries from guests asking about hygiene?
cord-298475-3bhiattkHave you received petitions of cancellations of bookings asking for 100% refund pushed by the platforms?
cord-298475-3bhiattkHave you received phone calls from'customers service'to encourage you to cancel bookings?
cord-298475-3bhiattkHow do you foresee your hosting practice evolving in the near future as a result of the pandemic?
cord-298475-3bhiattkHow has your hosting practice and operational activity changed as a result of the pandemic?
cord-298475-3bhiattkIn your opinion, how has the pandemic changed the P2P accommodation sector?
cord-298475-3bhiattkMapping the consequences of authentic consumption experiences for hotels and Airbnb Going back to its roots: can hospitableness provide hotels competitive advantage over the sharing economy?
cord-298475-3bhiattkThe impact of the SARS outbreak on Taiwanese hotel stock performance: an event- study approach What do Airbnb users care about?
cord-298475-3bhiattkThe impacts of quality and quantity attributes of Airbnb hosts on listing performance Coronavirus pandemic and tourism: Dynamic stochastic general equilibrium modeling of infectious disease outbreak Rethinking game consumption in tourism: a case of the 2019 novel coronavirus pneumonia outbreak in China Hotel cleanliness: will guests pay for enhanced disinfection?
cord-298475-3bhiattkWhat are the short- term economic impacts of the pandemic on your hosting activity?
cord-298475-3bhiattkWhat do you think the long- term economic impacts of covid-19 will be?
cord-298475-3bhiattkWhat makes an Airbnb host a superhost?
cord-298475-3bhiattkWhen are online ratings more trustworthy?
cord-298475-3bhiattkWhich measures are you planning to take to ensure a good level of hygiene is provided in your property(ies)?
cord-298475-3bhiattkWhy do Airbnb hosts discriminate?
cord-016717-2twm4hmc: what have we learned about natural selection in 15 years?
cord-016717-2twm4hmcAre there differences in immune function between continental and insular birds?
cord-016717-2twm4hmcBiodiversity: a continuing source of novel drug leads Epidemic disease decimates amphibian abundance, species diversity, and evolutionary history in the highlands of central Panama Using habitat models to map diversity: pan- African species richness of ticks( Acari: Ixodida) revisited: or why are there so many kinds of parasites in'the garden of earthly delights Distribution of specialist and generalist species along spatial gradients of habitat disturbance and fragmentation Evolution, consequences and future of plant and animal domestication Population dynamics of pathogens with multiple host species Sacred cows and sympathetic squirrels: the importance of biological diversity to human health Homage to Linnaeus: how many parasites?
cord-016717-2twm4hmcBut could this low exposure also induce evolutionary change in the ability of a host to respond to infection?
cord-016717-2twm4hmcC Cross- protection of hepatitis E virus genotypes 1 and 4 in rhesus macaques Is a healthy ecosystem one that is rich in parasites?
cord-016717-2twm4hmcCould it be possible that specialist species also carry hemorrhagic fever viruses, only these viruses have not yet been identified?
cord-016717-2twm4hmcDisease Ecology?
cord-016717-2twm4hmcHow many hosts?
cord-016717-2twm4hmcInfectious Disease Ecology?
cord-016717-2twm4hmcOr is there something intrinsic in opportunistic species that makes them more likely to evolve and maintain hemorrhagic fever viruses( Mills 2006)?
cord-016717-2twm4hmcParasite diversity: an overlooked metric of parasite pressures?
cord-016717-2twm4hmcRegarding the genetic diversity of host, an important issue is: to what extent does a reduction of this diversity impact the ability of the host population to response to infectious diseases?
cord-016717-2twm4hmcRegarding the genetic diversity of host, an important issue is: to what extent does a reduction of this diversity impact the ability of the host population to response to infectious diseases?
cord-016717-2twm4hmcScientific evidence supporting both of these views is beginning to emerge, but the core question remains: how is biodiversity linked to infectious disease?
cord-016717-2twm4hmcThe parasites of Homo sapiens: an annotated checklist of the protozoa, helminths and arthropods for which we are home Immunological change in a parasite- impoverished environment: divergent signals from four island taxa Effect of host diversity on disease dynamics Ecology: individuals, populations and communities Disease spread, susceptibility and infection intensity: vicious circles?
cord-016717-2twm4hmcThis then raises the following question: to what extent does a reduction of the genetic diversity in a host species impact the ability of the host population to response to infectious diseases( May 1995)?
cord-016717-2twm4hmcVirtues of being faithful: can we limit the genetic variation in human immunodeficiency virus?
cord-016717-2twm4hmcWhat could be the consequences of such a shift?
cord-016717-2twm4hmcWhat may happen in a world where increased movements of hosts and pathogens, high population densities, and rapidly changing environments increase contact rates, spread, and selective pressures on pathogens and hosts while at the same time a combination of low exposure to pathogen biodiversity and decreased genetic variability in some animals increases susceptibility to new diseases?
cord-016717-2twm4hmcWhy are murid species associated with hemorrhagic fever more generalist than those which are not?
cord-016717-2twm4hmckey: cord-016717- 2twm4hmc authors: Vourc’h, Gwenaël; Plantard, Olivier; Morand, Serge title: How Does Biodiversity Influence the Ecology of Infectious Disease?
cord-264884-ydkigome,, 2005?
cord-264884-ydkigomeA subset of human immunodefi ciency virus type 1 long- term nonprogressors is characterized by the unique presence of ancestral sequences in the viral population Does common architecture reveal a viral lineage spanning all three domains of life?
cord-264884-ydkigomeAccordingly, when contemplating the amazing complexity of the P1 immunity and how it evolved, Yarmolinsky posed the question;"Could the byzantine complexity of the controls at ImmI be the outcome, not of successive host- parasite accommodations, but of competition among related phages?"
cord-264884-ydkigomeAlso, how do we defi ne information content or integrity of a consortia?
cord-264884-ydkigomeCan cooperation( or consortia behavior) result from any of these models?
cord-264884-ydkigomeCan this be considered an example of symbiosis in the accepted sense?
cord-264884-ydkigomeCould the adaptation to a host- specifi c persistence- based basal life strategy provide some explanations for the evolution of the higher fi delity RNA replicase of these coronaviruses?
cord-264884-ydkigomeDNA Viral eukaryogenesis: was the ancestor of the nucleus a complex DNA virus?
cord-264884-ydkigomeDid the need and selection for a larger genome override the use of error to generate adaptability as seen in poliovirus and HIV-1?
cord-264884-ydkigomeDoes such a distributed pattern of evolution and gene novelty also apply to the phycodnaviruses?
cord-264884-ydkigomeHere a virus, there a virus, everywhere the same virus?
cord-264884-ydkigomeHow can genetic complexity be created in such a circumstance?
cord-264884-ydkigomeHow do we defi ne such fi tness since the mixture clearly matters?
cord-264884-ydkigomeHow does MHV attain such stable and prevalent persistence in natural population yet retain the ability to cause disease in naive populations?
cord-264884-ydkigomeHow generally important is this poliovirus in vivo quasispecies result?
cord-264884-ydkigomeHow important are viruses in general to evolutionary biology?
cord-264884-ydkigomeHow is information stability and higher fi tness attained with such errors?
cord-264884-ydkigomeHow might such selection operate in natural populations?
cord-264884-ydkigomeHow might we explain the increased fi delity and genome size of the nidoviruses?
cord-264884-ydkigomeHow then do we link poxvirus evolution to other more ancient DNA viruses, such as PBCV-1 which has the same DNA replication mechanism, but distinct replication proteins?
cord-264884-ydkigomeIf so, what selective pressures might have changed this seemingly basic feature?
cord-264884-ydkigomeIf so, why is it that in sheep a distinctly different lineage of retrovirus( enJSRV) was also selected to provide a related placental function to a another mammal with signifi cantly different placental reproductive biology?
cord-264884-ydkigomeIf we can accept the above conclusion concerning the role for viruses in the evolution of prokaryotes, we must then ask why such a successful evolutionary strategy was not apparently maintained in eukaryotes?
cord-264884-ydkigomeIs there any evidence that this result with poliovirus indeed represents a general virus- host evolutionary relationship in natural settings?
cord-264884-ydkigomeProtein repertoire of double- stranded DNA bacteriophages Characterization of the primary immunity region of the Escherichia coli linear plasmid prophage N15 Parvovirus variation for disease: a difference with RNA viruses?
cord-264884-ydkigomeWas there some change in viral adaptation in which quasispecies and generation of mixtures was no longer as important for adaptation?
cord-264884-ydkigomeWas this ERVL colonization of relevance to the ancient co- speciation of simian foamy virus and their primate host( Switzer et al., 2005)?
cord-264884-ydkigomeWhat could be more fascinating than a green sea slug- an animal that can use light for photosynthesis?
cord-264884-ydkigomeWhat do we know about the natural biology of these viruses, which might provide some insight into this?
cord-264884-ydkigomeWhat does structure tell us about virus evolution?
cord-264884-ydkigomeWhat exactly was the relevance of HERV endogenization to human survival and adaptations?
cord-264884-ydkigomeWhat is the fi tness consequence to the colony harboring MHV relative to its uninfected neighbor?
cord-264884-ydkigomeWhat maintains the MHV fi tness of natural persistence?
cord-264884-ydkigomeWhat then is the evolutionary relationship that links all of these seemingly distinct viruses?
cord-264884-ydkigomeWhat then is the fi tness and evolutionary consequence to E. coli harboring P1?
cord-264884-ydkigomeWhat was the role for SIV in the evolution of primate MHC( Vogel et al., 1999)?
cord-264884-ydkigomeWhy is this relationship stable?
cord-264884-ydkigomeWhy should prokaryotes and eukaryotes differ is such a fundamental way?
cord-264884-ydkigomeWhy?
cord-264884-ydkigomeWhy?
cord-264884-ydkigomehuman and chimpanzee MHC I( Watkins, 1995; Kulski et al., 1999)?
cord-264884-ydkigometailed DNA bacteriophages Do viruses form lineages across different domains of life?