This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.
| identifier | question |
|---|---|
| cord-016954-l3b6n7ej | Thus a particularly pertinent question is whether EAE is a suitable relevant research tool for MS? |
| cord-001017-4qfhltg4 | Tcell responses to human myelin protein- derived peptides Role of the innate immune system in the pathogenesis of multiple sclerosis T cells- innate immune lymphocytes? |
| cord-010016-fs8pjy1z | authors: WEBB, H. E.; FAZAKERLEY, J. K. title: CAN VIRAL ENVELOPE GLYCOLIPIDS PRODUCE AUTO‐IMMUNITY, WITH REFERENCE TO THE CNS AND MULTIPLE SCLEROSIS? |
| cord-003738-el0wyu74 | In addition, IL-4 treatment significantly reduced radial diffusivity( RD, λ?) in the EC( Fig 4F) and IC( Fig 4H), which likely indicates improved myelin integrity[ 25]. |
| cord-001396-rpnuauwz | The association of the human herpesvirus-6 and MS Could Epstein- Barr virus or canine distemper virus cause multiple sclerosis? |
| cord-000725-rafwlw0t | improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation Reactive astrocytes protect tissue and preserve function after spinal cord injury Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion Apoptosis of inflammatory cells in immune control of the nervous system: role of glia IFN- gamma shapes immune invasion of the central nervous system via regulation of chemokines Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6 Increased production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? |
| cord-005146-o3roa7br | Where are the sources of ectopic Schwann cells? |
| cord-021452-9rukc80y | an inappropriate standard of care Is the role of steroids in acute spinal cord injury now resolved? |
| cord-028963-u4iupl1s | Part II: noninfectious factors Is season of birth associated with multiple sclerosis? |
| cord-270458-7imgvale | what lessons have we learned? |
| cord-276587-ynionj5r | The role of chemokines during viral infection of the CNS Type I interferon: friend or foe? |
| cord-020770-wpub7krf | A polarizing question: do M1 and M2 microglia exist? |
| cord-003199-03c9rx3o | The olfactory vector hypothesis of neurodegenerative disease: is it viable? |
| cord-297325-fbilhauu | Noninfectious factors Ann Neurol Virus infection, antiviral immunity, and autoimmunity Epstein- Barr virus and multiple sclerosis Human herpes virus 6 and multiple sclerosis Plaque- associated expression of human herpesvirus 6 in multiple sclerosis Viral and bacterial antibody responses in multiple sclerosis Detection of coronavirus RNA and antigen in multiple sclerosis brain Dysregulated Epstein- Barr virus infection in the multiple sclerosis brain Infections and autoimmunity- friends or foes? |
| cord-021500-sy6lnt7b | I. Changes in the activities of 2',3'-cyclic nucleotide 3'-phosphohydrolase, oligodendroglial ceramide galactosyl transferase, and the hydrolysis of the alkenyl group of alkenyl, acyl- glycerophospholipids by plasmalogenase in different regions of the brain Mitogenic effect of axolemmaenriched fraction on cultured oligodendrocytes Shiverer, an autosomal recessive mutant mouse with myelin- deficiency Synthesis and incorporation of myelin polypeptide into CNS myelin In vivo and in vitro observations on laminin production by Schwann cells N- terminal sequence homology among retinoid- binding proteins from bovine retina Glial fibrillary acidic( GFA) protein in Schwann cells: fact or artifact? |
| cord-266441-sd117tzs | The Global Cancer Observatory Childhood brain lesions: 15 years experience of King Abdulaziz University Hospital Pattern of intracranial space- occupying lesions: the experience of the King Khalid University Hospital C.N.S. Tumors in Eastern Saudi Arabia Does brain tumor epidemiology differ from place to another? |
| cord-018034-gx5c9mk8 | The fate of skin monografts transplanted to the brain, to subcutaneous tissue and to the anterior chamber of the eye Tissue- specific migration of lymphocytes: a key role for Th1 and Th2 cells? |
| cord-018034-gx5c9mk8 | brain edema or vascular engorgement? |
| cord-007170-svsfu7fj | A possible etiological factor in human affective disorders? |
| cord-007170-svsfu7fj | Borna virus cDNA encoding a protein recognized by antibodies in humans with behavioral diseases Analysis of Borna disease virus- specific RNAs in infected cells and tissues Replication of Borna disease virus in cell cultures Influence of interferon on persistent infection caused by Borna disease virus in vitro Borna disease, a possible hazard for man? |
| cord-015684-q10sx1dm | HTR2A T102C and DRD3 Ser9Gly predict clinical improvement in patients with acutely exacerbated schizophrenia? |
| cord-015684-q10sx1dm | The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia Fibroblast and lymphoblast gene expression profi les in schizophrenia: are non- neural cells informative? |
| cord-266078-h53zpjab | The more the merrier? |
| cord-259347-3acsko74 | Is SARS- CoV-2 likely to be present in the central nervous system? |
| cord-008586-5jinvuyn | With all of these potential regulatory mechanisms for NOS-2 expression in mind, what is the evidence for expression in vivo? |
| cord-008586-5jinvuyn | what are the roles that NO from this source play in CNS function? |
| cord-272981-8gahvdt0 | All animals tested except? |
| cord-022163-7klzsrpu | Henipavirus and Tioman virus antibodies in pteropodid bats Replication and persistence of measles virus in defi ned subpopulations of human leukocytes Newcastle disease virus- vectored Nipah encephalitis vaccines induce B and T cell responses in mice and long- lasting neutralizing antibodies in pigs Virus infections in the nervous system Effects of canine distemper virus infection on lymphoid function in vitro and in vivo Rhabdovirus- based vaccine platforms against Henipaviruses Eph, a protein family coming of age: more confusion, insight, or complexity? |
| cord-022163-7klzsrpu | The distribution of henipaviruses in Southeast Asia and Australasia: is Wallace's line a barrier to Nipah virus? |
| cord-252389-xrdbmosj | A prospective clinical study of detailed neurological manifestations in patients with COVID-19 Comorbidity between neurological illness and psychiatric disorders Bidirectional relations among common psychiatric and neurologic comorbidities and epilepsy: do they have an impact on the course of the seizure disorder? |
| cord-252389-xrdbmosj | Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? |
| cord-267166-ecmayzr6 | Can both populations display protective functions? |
| cord-267166-ecmayzr6 | Do they display dynamic functions throughout the evolution of MS lesions? |
| cord-298847-szezd2vb | A light- and electronic- microscopic study Susceptibility of murine CNS to OC43 infection Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits Does viral disease underlie ALS? |
| cord-004911-fbge8tkc | Do neurological signs occur in experimental allergic encephalomyelitis in the absence of inflammatory lesions of the central nervous system? |
| cord-004911-fbge8tkc | Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia- positive cells with dendritic morphology Microglia in degenerative neurological disease Indentification of Ia glycoprotein in rat thymus and purification from rat spleen Alzheimer's disease- synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts Inflammatory cytokines in the brain: does the CNS shape immune responses? |
| cord-008523-avkgldnp | The development of hind- limb paralysis in B 10.A(18R) mice, in the absence of mutations in either CTL epitope, suggests that a factor expressed on the C57BL/6 background( decreased production of antibody?) may contribute to the increased amount of virus replication observed in these mice. |
| cord-008523-avkgldnp | What can be concluded from these studies about the role of CTL escape mutants in the pathogenesis of viral infections in the CNS? |
| cord-021772-5v4gor2v | Clinical and clinicopathological features of non- suppurative meningoencephalitis in young greyhounds in Ireland Cerebrospinal fluid eosinophilia in dogs What is your diagnosis? |
| cord-021772-5v4gor2v | What is your diagnosis? |
| cord-271176-wdc4p4bc | The infectious agent: known or unknown? |
| cord-271176-wdc4p4bc | Why is IFN- ␥ insufficient to control tuberculosis? |
| cord-002209-xs6qigg4 | Astrocyte activation( mild astrogliosis): a pro- reparative phenotype? |
| cord-002209-xs6qigg4 | The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus Distinct stages of myelination regulated by gamma- secretase and astrocytes in a rapidly myelinating CNS coculture system Immunocytochemical study of myelinassociated glycoprotein( MAG), basic protein( BP), and glial fibrillary acidic protein( GFAP) in chronic relapsing experimental allergic encephalomyelitis( EAE) Astrocytes- friends or foes in multiple sclerosis? |
| cord-002209-xs6qigg4 | The interleukin 1 receptor: ligand interactions and signal transduction Myelination: do astrocytes play a role? |
| cord-290566-tmsocyfc | Do cytokines trigger oV exacerbations? |
| cord-311845-wnk7itha | Molecular approaches to spinal cord repair Changes at the nodal and perinodal axonal domains: a basis for multiple sclerosis pathology? |
| cord-030371-wp6xmaqe | lighting up neurologic diseases? |
| cord-030371-wp6xmaqe | positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients Characterization of plaques using 18F- FDG PET/ CT in patients with carotid atherosclerosis and correlation with matrix metalloproteinase-1 Vascular inflammation evaluated by[ 18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome Evaluation of carotid plaque inflammation in patients with active rheumatoid arthritis using( 18)F- fluorodeoxyglucose PET- CT and MRI: a pilot study What can be seen by 18F- FDG PET in atherosclerosis imaging? |
| cord-278684-txlvla0j | Actions and mechanisms of action Natural and experimental Borna disease in animals Borna disease, a possible hazard for man? |
| cord-278684-txlvla0j | Borna disease virus: A possible etiologic factor for human affective disorders? |
| cord-009577-29u7pdpk | By taking genomic segments from neuroinvasive and noninvasive strains, one can ask the question: which genome segment is responsible for the ability to penetrate the CNS? |
| cord-009577-29u7pdpk | Enhancer elements Continuous cultures of fused cells secreting antibodies of predetermined specificity Moloney sarcoma virus Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide Is the acetylcholine receptor a rabies virus receptor? |
| cord-009577-29u7pdpk | Tyler and collaborators exploited this fact to test reassortants of type 1 and type 3 viruses and again ask the question: which gene segmeiit accounts for the different patterns of spread in these two strains? |
| cord-002757-upwe0cpj | : can we retain the clinical use of mold- active antifungal azoles? |
| cord-002757-upwe0cpj | Contribution of Working Groups I, II and III to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change Impact of climate change in the epidemiology of vector- borne diseases in domestic carnivores Impact of climate change on human infectious diseases: empirical evidence and human adaptation Climate change and health: global to local influences on disease risk Climate change and mosquito- borne disease Climate of origin affects tick( Ixodes ricinus) host- seeking behavior in response to temperature: implications for resilience to climate change? |
| cord-002757-upwe0cpj | The burden of co- infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub- saharan Africa Is there an interaction between human immunodeficiency virus and Plasmodium falciparum? |
| cord-022395-rk31pwoa | Characterisation of microglia isolated from adult human and rat brain Astrocytes: Auxiliary cells for immune responses in the central nervous system? |
| cord-022395-rk31pwoa | Is the acetylcholine receptor a rabies virus receptor? |
| cord-022395-rk31pwoa | What's new in cerebral pathology in acquired immune deficiencies? |
| cord-309109-c5hajb6k | How does CNS demyelination occur? |
| cord-302796-zi3p2k1b | What is immune privilege( not)? |
| cord-302796-zi3p2k1b | What is the blood- brain barrier( not)? |
| cord-277679-sc9hugxr | Imaging of acute disseminated encephalomyelitis COVID-19: consider cytokine storm syndromes and immunosuppression Why now? |
| cord-277679-sc9hugxr | the beginning of another SARS- like pandemic? |
| cord-022594-fx044gcd | Does the history of multiple sclerosis go back as far as the 14th century? |
| cord-022594-fx044gcd | The 150-year anniversary of multiple sclerosis: Does its early history give an etiological clue? |
| cord-022594-fx044gcd | When should treatment be initiated in patients with very early demyelinating disease? |
| cord-325624-6anybxnk | When can axonal injury be beneficial? |
| cord-018042-qt7055fw | ( 2) Is there a cause and effect relationship between the production of a particular chemokine( or chemokines) and the development of specific molecular and cellular neuropathological alterations? |
| cord-018042-qt7055fw | ( 4) Could manipulation of the chemokines or their receptors be used as a rational means for therapeutic intervention? |
| cord-018042-qt7055fw | Some key questions include:( 1) Do the presence of chemokines in different disordered states reflect their primary involvement or is an epiphenomenon? |
| cord-018042-qt7055fw | What are the mechanisms that underlie chemokinemediated actions in the CNS? |
| cord-329750-purunxce | 1b in MS Are statins a treatment option for multiple sclerosis? |
| cord-017499-51yy7y9n | Anesthesie et Reanimation Hemodynamic changes following corticosteroid and naloxone infusion in dogs subjected to hypovolemic shock without resuscitation Nitrous oxide as an adjunct to narcotic anesthesia Does nitrous oxide or a reduced FI02 alter the hemodanymic function during high dose sufentanil anesthesia? |
| cord-017499-51yy7y9n | Chemical structure: How fatty is the drug( i.e. its lipophilicity)? |
| cord-017499-51yy7y9n | Does the drug have nutrients that our brain uses? |
| cord-017499-51yy7y9n | Route of administration: Is the drug entering directly into the blood stream or is it entering first into the stomach? |
| cord-017144-k7fqneup | IFN-? |
| cord-017144-k7fqneup | In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseases Role of nitric oxide in HIV-1 infection: friend or foe? |
| cord-017144-k7fqneup | The microbicidal activity of interferon- gamma- treated macrophages against Trypanosoma cruzi involves an Larginine- dependent, nitrogen oxide- mediated mechanism inhibitable by interleukin-10 and transforming growth factor- beta Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis Different susceptibility of three clinically isolated strains of Cryptococcus neoformans to the fungicidal effects of reactive nitrogen and oxygen intermediates: possible relationships with virulence Control of the autoimmune response by type 2 nitric oxide synthase Nitric oxide; A pathogenic factor in autoimmunity Nitric oxide in autoimmune disease: cytotoxic or regulatory mediator? |
| cord-017144-k7fqneup | and IL-1B induce nitric oxide formation from primary mouse astrocytes Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine Appearance of inducible nitric oxide synthase in the rat central nervous system after rabies virus infection and during experimental allergic encephalomyelitis but not after peripheral administration of endotoxin Does nitric oxide play a critical role in viral infections? |
| cord-353298-vr5hnzp8 | Infected mice exhibit clinical signs of CNS demyelin- ation within the first week post infection( wpi)? |
| cord-262281-56tbrl8a | -where does it end? |
| cord-262281-56tbrl8a | The cellular pathology of Parkinson's disease Controversy: is Parkinson's disease a single disease entity? |
| cord-262281-56tbrl8a | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease Is Parkinson's disease a primary olfactory disorder? |
| cord-262281-56tbrl8a | Where does Parkinson disease pathology begin in the brain? |
| cord-331268-kzy33hdb | : Relationship to a retrovirus? |
| cord-330553-sukrjl22 | Neurotoxicity A polarizing question: Do M1 and M2 microglia exist? |
| cord-311847-2czqs84q | Common Findings in COVID-19 Patients First case of 2019 novel coronavirus disease with Encephalitis Guillain- Barré syndrome associated with SARS- CoV-2 infection: Causality or coincidence? |
| cord-311847-2czqs84q | Underestimated Opportunistic Pathogens of the Central Nervous System? |
| cord-328763-hcbs20a0 | Producing GM- CSF: a unique T helper subset? |
| cord-328763-hcbs20a0 | Why did IL-12/ IL-23 antibody therapy fail in multiple sclerosis? |
| cord-288111-0ufc54kw | Histopathologic abnormalities consist of new demyelinative lesions infiltrated by mononuclear cells located primarily in the brain stem and the spinal cord.? |
| cord-288111-0ufc54kw | In this context it is of interest to note that in postinfectious encephalomyelitis in man associated with rubella, varicella, or measles, an MBP- specific lymphoproliferative response has been observed?'4. |
| cord-288111-0ufc54kw | This observation led to an interesting experiment in which a rabbit was immunized with a synthetic peptide from such a sequence of the hepatitis B virus polymerase?' |
| cord-294812-nnlzwaf1 | The aetiology of tuberculosis( translation of Die Aetiologie der Tuberculose( 1882) Sequence- based identification of microbial pathogens: a reconsideration of Koch's postulates The environment and disease: association or causation? |
| cord-294812-nnlzwaf1 | Viral infections in immunocompromised patients: what's new with respiratory viruses? |
| cord-294812-nnlzwaf1 | Viruses associated with pneumonia in adults Emerging respiratory agents: new viruses for old diseases? |
| cord-345339-kyboibtq | The HHV6 paradox: ubiquitous commensal or insidious pathogen? |
| cord-253797-a9lmfaho | Is apolipoprotein Da mammalian bilin- binding protein? |
| cord-253797-a9lmfaho | Yet, the exact rofe reactive Abbrsviahzs: ACT, antichymotrypsin: AD, Alzheimer's disease; ADC, AlDS dementia complex; ALS, amyotrophic lateral sclerosis; APP, amyloid/? |
| cord-253797-a9lmfaho | another role for the NMDA receptor? |
| cord-253797-a9lmfaho | astrocytes Neuronal regulation of astroglial morphology and proliferation in vitro Astrocytes: auxiliary cells for immune responses in the central nervous system? |
| cord-276533-cxyndepl | A critical question is what are the receptors that are concentrated in the coated pit? |
| cord-276533-cxyndepl | If activated macrophages serve as the final effector arm in demyelination and if macrophage activation is immune mediated, what is the antigen specificity of the immune response producing the activation and why does n't demyelination follow every inflammatory response in the brain such as those associated with viral infections? |
| cord-276533-cxyndepl | If most or all of the CSF Ig is not directly related to the cause of the disease, why do elevated levels occur in the CSF? |
| cord-276533-cxyndepl | These include: what is the actual mechanism of myelin destruction; what is the antigen or antigens responsible for initiating the disease process; how is antigen presented to immune T cells in the CNS and is the genetic influence on susceptibility involved at this stage; what is the role of an environmental or infectious agent in the disease; and finally, what accounts for the fluctuating nature of the disease? |
| cord-329527-0rlotyz3 | Taxonomy of the order Mononegavirales: update 2016 H1N1 encephalitis with malignant edema and review of neurologic complications from influenza Neurological complications of middle east respiratory syndrome coronavirus: a report of two cases and review of the literature Human metapneumovirus persists in BALB/ c mice despite the presence of neutralizing antibodies Taxonomy of the order Mononegavirales: update 2018 Bronchiolitis- associated encephalopathy in critically- ill infants: an underestimated complication? |
| cord-329527-0rlotyz3 | what have we learnt from the ordeal? |
| cord-353812-4oxbczqe | Associated with SARS- CoV-2 International consensus diagnostic criteria for neuromyelitis optica spectrum disorders Nervous system involvement after infection with COVID-19 and other coronaviruses Encephalitis as a clinical manifestation of COVID-19 Clinical analysis of multiple organ dysfunction syndrome in patients suffering from SARS SARS- CoV-2 can induce brain and spine demyelinating lesions Guillain- Barré syndrome associated with SARS- CoV-2 infection: causality or coincidence? |
| cord-315656-asvf4roo | : at the crossroad between aging and neurodegeneration Impact of SARS- CoV-2 infection on neurodegenerative and neuropsychiatric diseases: a delayed pandemic Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? |
| cord-315656-asvf4roo | a review Neurological associations of COVID-19 Does SARS- CoV-2 infection cause chronic neurological complications? |
| cord-315656-asvf4roo | bioRxiv Effects of COVID-19 on the nervous system Neurologic Alterations Due to Respiratory Virus Infections Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? |
| cord-023026-2r84ndzv | Does transplantation of healthy endothelial cells have a beneficial effect on the outcome of ischemic brain damage? |
| cord-299949-kmn53e2z | Flaviviruses are neurotropic, but how do they invade the CNS? |
| cord-299949-kmn53e2z | Gamma interferon- dependent, noncytolytic clearance of sindbis virus infection from neurons in vitro Control of sindbis virus infection by antibody in interferon- deficient mice Maturation- dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons Neurons under viral attack: victims or warriors? |
| cord-299949-kmn53e2z | How do immune cells support and shape the brain in health, disease, and aging? |
| cord-334499-fz7vrnb1 | RAG1-/-? |
| cord-334499-fz7vrnb1 | vasculopathy are directed against VZV Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis Complement and demyelinating disease: no MAC needed? |
| cord-317651-lsca8vt2 | NATURE REVIEWS| NEUROSCIENCE VOLUME 2| JULY 2001| 5 0 9 bition to treat specific CNS diseases? |
| cord-317651-lsca8vt2 | This details the mechanisms by which several MMP members are activated Matrix Metalloproteinase Inhibitors in Cancer Therapy Matrix Metalloproteinases and TIMPS Relating matrix metalloproteinase structure to function: why the'hemopexin'domain? |
| cord-317651-lsca8vt2 | What could they be? |
| cord-320909-p93gxjm2 | : cord-320909-p93gxjm2 authors: Natoli, S.; Oliveira, V.; Calabresi, P.; Maia, L. F.; Pisani, A. title: Does SARS‐Cov‐2 invade the brain? |
| cord-320909-p93gxjm2 | Prophylactic and therapeutic remdesivir( GS-5734) treatment in the rhesus macaque model of MERS- CoV infection Guillain- Barr e syndrome associated with SARS- CoV-2 infection: causality or coincidence? |
| cord-320909-p93gxjm2 | Viral and cellular factors involved in neuroinvasiveness and neuropathogenesis Multiple organ infection and the pathogenesis of SARS Interaction of severe acute respiratory syndrome- associated coronavirus with dendritic cells Is there an ideal animal model for SARS? |
| cord-303741-1ou0cy5k | Does SARS- Cov-2 invade the brain? |
| cord-303741-1ou0cy5k | Why do children seem to be more protected against COVID-19? |
| cord-303741-1ou0cy5k | causes disease?). |
| cord-303741-1ou0cy5k | once there( e.g., infects neural cells? |
| cord-342204-9tgxijvn | Acute and Persistent Infection of Human Neural Cell Lines by Human Coronavirus OC43 Neuroinvasion by human respiratory coronaviruses Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox? |
| cord-342204-9tgxijvn | the key players in the neurodegenerative diseases? |
| cord-355413-ls2nud43 | : a model virus made useful? |
| cord-355413-ls2nud43 | The instructive role of innate immunity in the acquired immune response The natural killer cell- friend or foe in autoimmune disease? |
| cord-262786-otxpc46a | Immediate and long- term consequences of COVID-19 infections for the development of neurological disease Cranial neuropathies and COVID-19: neurotropism and autoimmunity Large artery ischaemic stroke in severe acute respiratory syndrome( SARS) Is the collapse of the respiratory center in the brain responsible for respiratory breakdown in COVID-19 patients? |
| cord-262786-otxpc46a | Neurological involvement in SARS- CoV-2 infection: a clinical systematic review Impact of SARS- CoV-2 infection on neurodegenerative and neuropsychiatric diseases: a delayed pandemic? |
| cord-262786-otxpc46a | SARS- CoV-2 can induce brain and spine demyelinating lesions Cerebrovascular disease in COVID-19 Disease in COVID-19: Is there a higher risk of stroke? |
| cord-262786-otxpc46a | The cognitive consequences of the COVID-19 epidemic: collateral damage? |
| cord-262786-otxpc46a | commonly The hypothalamus as a hub for SARS- CoV-2 brain infection and pathogenesis Cerebrovascular and neurological dysfunction under the threat of COVID-19: is there a comorbid role for smoking and vaping? |
| cord-002119-kl431ev6 | ( SK2) modulates hippocampal learning, memory, and synaptic plasticity Calcium signalling: dynamics, homeostasis and remodelling Local calcium signaling in neurons Remyelination after spinal cord injury: is it a target for repair? |
| cord-002119-kl431ev6 | CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries B cell selection and susceptibility to autoimmunity Human innate B cells: a link between host defense and autoimmunity? |
| cord-002119-kl431ev6 | CXCL10 enhances tissue sparing and angiogenesis following spinal cord injury Cellular inflammatory response after spinal cord injury in Sprague- Dawley and Lewis rats Macrophage activation and its role in repair and pathology after spinal cord injury Rats and mice exhibit distinct inflammatory reactions after spinal cord injury Neuroprotection and acute spinal cord injury: a reappraisal Astrocyte roles in traumatic brain injury Microglia and inflammation: conspiracy, controversy or control? |
| cord-002119-kl431ev6 | Do chemokines mediate inflammatory cell invasion of the central nervous system parenchyma? |
| cord-002119-kl431ev6 | Is neuroinflammation in the injured spinal cord different than in the brain? |
| cord-002119-kl431ev6 | an immunohistochemical study GeneChip5 analysis after acute spinal cord injury in rat Activated human T cells, B cells, and monocytes produce brain- derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? |
| cord-253201-r6vsa0pw | Does SARS Cov 2 invade the brain? |
| cord-253201-r6vsa0pw | Specific EEG Encephalopathy Pattern in SARS- CoV-2 Patients Brain MRI findings in patients in the intensive care unit with COVID-19 infection Cerebrovascular and Neurological Dysfunction under the Threat of COVID-19: Is There a Comorbid Role for Smoking and Vaping? |
| cord-253201-r6vsa0pw | The Journal of infectious diseases Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? |
| cord-253201-r6vsa0pw | Underestimated Opportunistic Pathogens of the Central Nervous System? |
| cord-253201-r6vsa0pw | What should radiologists need to know? |
| cord-351398-ftkrd1tj | Do the intrinsic properties of the membrane prevent immune mediated cytotoxic attack? |
| cord-351398-ftkrd1tj | I mediated cytotoxicity? |
| cord-351398-ftkrd1tj | I molecules are they deficient in processing of the appropriate peptide? |
| cord-351398-ftkrd1tj | I molecules to initiate a cytolytic attack? |
| cord-316227-dgyxbgvg | The intrathecal, polyspecific antiviral immune response: Specific for MS or a general marker of CNS autoimmunity? |
| cord-316227-dgyxbgvg | What could be the mechanism of the selective shift from Th1 to Th1/17 cells in the analyzed patients with MS? |
| cord-316227-dgyxbgvg | authors: Geginat, Jens; Paroni, Moira; Pagani, Massimiliano; Galimberti, Daniela; De Francesco, Raffaele; Scarpini, Elio; Abrignani, Sergio title: The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance? |
| cord-316227-dgyxbgvg | distinguish myelin- reactive T cells from patients with multiple sclerosis Recognition of viral and self- antigens by TH1 and TH1/ TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis Degenerate T- cell receptor recognition, autoreactive cells, and the autoimmune response in multiple sclerosis Activation of myelin reactive T cells in multiple sclerosis, a possible role for T cell degeneracy? |
| cord-009997-oecpqf1j | Questions addressed their current feeding route and perception, for example,"What aspect(s) of tube feedings are beneficial to you?" |
| cord-009997-oecpqf1j | The question remains: which mechanisms influence platelet immune function and are they developmentally regulated? |
| cord-009997-oecpqf1j | and"What aspect(s) of tube feeding worry or scare you? |
| cord-275795-ee7qyw5h | Alpha- beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection Correlates of protective immunity in poxvirus infection: where does antibody stand? |
| cord-275795-ee7qyw5h | Circulating rotavirus- specific T cells have a poor functional profile Fulfilling the promise of rotavirus vaccines: how far have we come since licensure? |
| cord-275795-ee7qyw5h | Intracellular IFN- gamma expression in natural killer cells precedes lung CD8 þ T cell recruitment during respiratory syncytial virus infection HBV pathogenesis in animal models: recent advances on the role of platelets Basis of rabies virus neurovirulence in mice: expression of major histocompatibility complex class I and class II mRNAs Postlicensure effectiveness of varicella vaccine during an outbreak in a child care center Management of rabies in humans Vaccinia virus vaccines: past, present and future Hepatitis A virus in West Africa: is an epidemiological transition beginning? |
| cord-275795-ee7qyw5h | The T¼4 envelope of Sindbis virus is organized by interactions with a complementary T¼3 capsid Bystander target cell lysis and cytokine production by dengue virus- specific human CD4(þ) cytotoxic T- lymphocyte clones What is immune privilege( not)? |
| cord-275795-ee7qyw5h | The global burden of viral hepatitis from Analysis of T cell responses during active varicella- zoster virus reactivation in human ganglia REVIEW PAPER: pathology of animal models of alphavirus encephalitis Interview about immune privilege with Memory CD8 T cells in RSV infection: friend or foe? |
| cord-292255-zafnq8gl | A phase I/ II dose- escalation trial of vitamin D3 and calcium in multiple sclerosis Modulation of the immune system by UVradiation: more than just the effects of vitamin D? |
| cord-292255-zafnq8gl | Commensal gut flora and brain autoimmunity: a love or hate affair? |
| cord-292255-zafnq8gl | Myelin basic protein and human coronavirus 229E crossreactive T cells in multiple sclerosis Cross- reactivity of autoreactive T cells with MBP and viral antigens in patients with MS A functional and structural basis for TCR cross- reactivity in multiple sclerosis Epstein- Barr virus latent infection and BAFF expression in B cells in the multiple sclerosis brain: implications for viral persistence and intrathecal B- cell activation Combinatorial antibody library from multiple sclerosis patients reveals antibodies that cross- react with myelin basic protein and EBV antigen HLA- B7-restricted EBV- specific CD8+ T cells are dysregulated in multiple sclerosis CD8+ T- cell deficiency, Epstein- Barr virus infection, vitamin D deficiency, and steps to autoimmunity: a unifying hypothesis Epigenetic dysregulation of the host cell genome in Epstein- Barr virusassociated neoplasia Cigarette smoking and incidence of multiple sclerosis Smoking is a risk factor for early conversion to clinically definite multiple sclerosis Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis Smoking and disease progression in multiple sclerosis Cigarette smoking and progression in multiple sclerosis Cigarette smoking and the progression of multiple sclerosis Smoking is associated with progressive disease course and increased progression in clinical disability in a prospective cohort of people with multiple sclerosis Impact of smoking on inflammation: overview of molecular mechanisms Smoking and two human leukocyte antigen genes interact to increase the risk for multiple sclerosis Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor Smoking and matrixmetalloproteinases, neutrophil elastase and myeloperoxidase in chronic periodontitis Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome Smoking induces differential miRNA expression in human spermatozoa: a potential transgenerational epigenetic concern? |
| cord-292255-zafnq8gl | Part I: the role of infection Multiple sclerosis: an immune or neurodegenerative disorder? |
| cord-292255-zafnq8gl | The immune system and the gut microbiota: friends or foes? |
| cord-311908-sgdq6j6x | A randomized, placebo- controlled, double- blind study Clinical viral infections and multiple sclerosis Effects of in¯uenza vaccination and in¯uenza illness on exacerbations in multiple sclerosis Analysis of the molecular basis of neuropathogenesis of RNA viruses in experimental animals: relevance for human disease? |
| cord-311908-sgdq6j6x | Mechanism of action Chemokines and chemokine receptors in CNS pathology Encephalitis after hepatitis B vaccinationÐRecurrent disseminated encephalitis or MS? |
| cord-311908-sgdq6j6x | Multiple sclerosis and childhood infections Serendipity and multiple sclerosis epidemiology Is sporadic MS caused by an infection of adolescence and early childhood? |
| cord-311908-sgdq6j6x | Russell WC Viral etiology of multiple sclerosis: where does the truth lie? |
| cord-311908-sgdq6j6x | apoptosis or necrosis? |
| cord-284038-93s3ffoy | A Potential New Neuropsychiatric Condition Triggered by Novel Coronavirus Infection and the Inflammatory Response? |
| cord-284038-93s3ffoy | COVID-19-White matter and globus pallidum lesions: Demyelination or small- vessel vasculitis? |
| cord-284038-93s3ffoy | COVID-19: What do we need to know about ICU delirium during the SARS- CoV-2 pandemic? |
| cord-284038-93s3ffoy | The New England journal of medicine Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? |
| cord-284038-93s3ffoy | Underestimated Opportunistic Pathogens of the Central Nervous System? |
| cord-284038-93s3ffoy | medRxiv Epidemiological, clinical characteristics of cases of SARS- CoV-2 infection with abnormal imaging findings Guillain- Barré syndrome associated with SARS- CoV-2 infection: causality or coincidence? |
| cord-283850-kt8n6pg2 | Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? |
| cord-283850-kt8n6pg2 | Cureus 12 Neurologic manifestations of severe respiratory viral contagions Septic encephalopathy and septic encephalitis Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Hypertension in patients with coronavirus disease 2019( COVID-19): a pooled analysis How do immune cells support and shape the brain in health, disease, and aging? |
| cord-283850-kt8n6pg2 | Outcome of delirium in critically ill patients: systematic review and meta- analysis Sepsis- associated encephalopathy: from delirium to dementia? |
| cord-283850-kt8n6pg2 | Past exposure to vaccines and subsequent risk of Alzheimer's disease COVID-19: gastrointestinal symptoms and potential sources of 2019-nCoV transmission Early- life adversity, systemic inflammation and comorbid physical and psychiatric illnesses of adult life Astrogliopathology: a central element of neuropsychiatric diseases? |
| cord-283850-kt8n6pg2 | Psychiatric comorbidities go untreated in patients with epilepsy: ignorance or denial? |
| cord-283850-kt8n6pg2 | Systematic review of proinflammatory cytokines in obsessive- compulsive disorder Blood levels of interleukin-1 beta, interleukin-6 and tumor necrosis factor- alpha and cognitive functions in patients with obsessive compulsive disorder Plasma cytokine abnormalities in drug- naïve, comorbidity- free obsessive- compulsive disorder Psychiatric comorbidities go unrecognized in patients with epilepsy Common psychiatric comorbidities in epilepsy: how big of a problem is it? |
| cord-337365-hugenn14 | HSV-1 can be treated, but can WNV or enteroviruses? |
| cord-337365-hugenn14 | What role does the RIPK3 signaling pathway in microglia play in viral encephalitis? |
| cord-337365-hugenn14 | phagocyte immunity and the neuropathogenesis of HIV-1 infection Regulated expression of sodium- dependent glutamate transporters and synthetase: a neuroprotective role for activated microglia and macrophages in HIV infection? |
| cord-337365-hugenn14 | scapegoat, saboteur, or something else? |
| cord-008530-yni0poh9 | : what chemokine is that? |
| cord-008530-yni0poh9 | A novel CXC chemokine PBSF/ SDF-1 and its receptor CXCR4: their functions in development, hematopoiesis and HIV infection Induction of IP-10 chemokine promoter by measles virus: comparison with interferon- gamma shows the use of the same response element but with differential DNA- protein binding profiles Molecular cloning, functional expression, and signaling characteristics of a C- C chemokine receptor Localization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? |
| cord-008530-yni0poh9 | Do chemokines mediate leukocyte recruitment in post- traumatic CNS inflammation? |
| cord-008530-yni0poh9 | How does CNS chemokine expression contribute to the pathogenesis of neuroinflammatory disease states? |
| cord-008530-yni0poh9 | Inflammatory cytokines in the brain: does the CNS shape immune responses? |
| cord-008530-yni0poh9 | Modulating chemokines: more lessons from viruses Neuroinvasion of simian immunodeficiency virus coincides with increased numbers of perivascular macrophages/ microglia and intrathecal immune activation Dynamic regulation of a- and~-chemokine expression in the central nervous system during mouse hepatitis virus- induced demyelinating disease Murine coronavirus infection: a paradigm for virus- induced demyelinating disease A central role for CD4+ T- cells and RANTES in virus- induced central nervous system inflammation and demyelination Chemokine receptors in the human brain and their relationship to HIV infection CXCR-4( Fusin), a co- receptor for the type 1 human immunodeficiency virus( HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons Cerebrospinal fluid beta chemokine concentrations in neurocognitively impaired individuals infected with human immunodeficiency virus type 1 A novel chemokine receptor- like protein, functions as a fusion cofactor for both macrophage- tropic and T cell line- tropic HIV-1 Chemokine receptors: keys to AIDS pathogenesis? |
| cord-008530-yni0poh9 | Tropical spastic paraparesis: a model of virus- induced, cytotexic T- cell- mediated demyelination? |
| cord-308201-lavcsqov | A reconsideration of Koch's postulates The Environment and Disease: Association or Causation? |
| cord-308201-lavcsqov | New respiratory viral infections Emerging respiratory agents: New viruses for old diseases? |
| cord-308201-lavcsqov | What's new with respiratory viruses? |
| cord-308201-lavcsqov | authors: Desforges, Marc; Le Coupanec, Alain; Dubeau, Philippe; Bourgouin, Andréanne; Lajoie, Louise; Dubé, Mathieu; Talbot, Pierre J. title: Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? |
| cord-295041-5vpawtef | ( SARS- CoV-2) Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host- virus interaction, and proposed neurotropic mechanisms Can the enteric nervous system be an alternative entrance door in SARS- CoV2 neuroinvasion? |
| cord-295041-5vpawtef | A mechanism of virus- induced demyelination Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system? |
| cord-295041-5vpawtef | COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role? |
| cord-295041-5vpawtef | How Covid-19 can damage the brain Neurological manifestations in severe acute respiratory syndrome Guillain- Barré syndrome associated with SARS- CoV-2 infection: causality or coincidence? |
| cord-295041-5vpawtef | More Prevalent Than Acknowledged? |
| cord-295041-5vpawtef | causative or coincidental? |
| cord-324619-y7gilopu | Covid-19 in patients presenting with influenza- like symptoms Self- reported olfactory and taste disorders in SARS- CoV-2 patients: a cross- sectional study Olfactory and gustatory dysfunctions as a clinical presentation of mild- to- moderate forms of the coronavirus disease( COVID-19): a multicenter European study Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? |
| cord-324619-y7gilopu | Smooth or Risky Revisit of an Old Malaria Drug for COVID-19? |
| cord-324619-y7gilopu | The gut as a neurological organ Can the enteric nervous system be an alternative entrance door in SARS- CoV2 neuroinvasion? |
| cord-324619-y7gilopu | a strategy for viral dissemination Enterovirus infections of the central nervous system Flaviviruses are neurotropic, but how do they invade the CNS? |
| cord-324619-y7gilopu | long- term neurologic effects of COVID-19? |
| cord-023143-fcno330z | *? |
| cord-023143-fcno330z | , Cara Wilsont, Kelledy Mansons, Michael Wyands, Bruce Walker?, Ronald C. Desrosiers |
| cord-023143-fcno330z | However, productive virus replication is minimized by antiviral CD8 T cells which suppress( kill?) |
| cord-023143-fcno330z | PrP genes were used to demonstrate that the"specie9 bank?' |
| cord-023143-fcno330z | The interferons( IFNs) a n? a family of cytokines whose functions include the protection of cells against viral infection. |
| cord-023143-fcno330z | Thes? |
| cord-023143-fcno330z | ofthe influenza HA protein from this second promoter in baby hamster kidney( BHK) cells was approximately 50?? |
| cord-023143-fcno330z | ofthe influenza HA protein from this second promoter in baby hamster kidney( BHK) cells was approximately 50?? |
| cord-322728-10m3xscs | Coeliac disease and schizophrenia Coeliac disease and schizophrenia Celiac disease and schizophrenia Is schizophrenia rare if grain is rare? |
| cord-322728-10m3xscs | Environmental Health Perspectives Is celiac disease a clue to the pathogenesis of schizophrenia? |
| cord-322728-10m3xscs | Prenatal exposure to cigarette smoke causes persistent changes in the oxidative balance and in DNA structural integrity in rats submitted to the animal model of schizophrenia Non- dietary forms of treatment for adult celiac disease Is there an association between peripheral immune markers and structural/ functional neuroimaging findings? |
| cord-322728-10m3xscs | The schizophrenia- rheumatoid arthritis connection: infectious, immune, or both? |
| cord-322728-10m3xscs | a contributing cause? |
| cord-322728-10m3xscs | do some cases of schizophrenia have an autoimmune basis? |
| cord-322728-10m3xscs | missing link in the pathogenesis of schizophrenia Antibodies to Toxoplasma gondii in individuals with first- episode schizophrenia Are some cases of psychosis caused by microbial agents? |
| cord-332109-ont0tqpn | A Nationwide Case- Control Study Overdose and risk factors for coronavirus disease 2019 Alcohol use and misuse during the COVID-19 pandemic: A potential public health crisis? |
| cord-332109-ont0tqpn | A multicenter, single- blind, randomized controlled trial Favipiravir, an antiviral for COVID-19? |
| cord-332109-ont0tqpn | Cardiovascular effects of marijuana and synthetic cannabinoids: The good, the bad, and the ugly Marijuana use and brain immune mechanisms Harmful Effects of Smoking Cannabis: A Cerebrovascular and Neurological Perspective Marijuana and chronic obstructive lung disease: A population- based study Does smoking marijuana increase the risk of chronic obstructive pulmonary disease? |
| cord-332109-ont0tqpn | Chronic nicotine treatment induces T cell anergy Are healthy smokers really healthy? |
| cord-332109-ont0tqpn | The Relationship between Alcohol Consumption and Vascular Complications and Mortality in Individuals With Type 2 Diabetes Habitual alcohol consumption is associated with lower cardiovascular stress responses- A novel explanation for the known cardiovascular benefits of alcohol? |
| cord-332109-ont0tqpn | The blood- brain barrier and methamphetamine: Open sesame? |
| cord-332109-ont0tqpn | Why is parkinsonism not a feature of human methamphetamine users? |
| cord-005393-rhji4io9 | As detected by immunohistochemical analysis, the addition of IFN-7 to brain cells in culture results in 9% of neurons expressing MHC class I, whereas direct injection into the CNS results in approx 15% of neurons expressing MHC class I. Moreover, the response of the OLB21 neuronal cell line to IFN-? has been investigated( Joly and Oldstone, 1992). |
| cord-005393-rhji4io9 | IFN-? |
| cord-005393-rhji4io9 | IFN-? also plays a role in regulating antibody production, promoting an IgG2a response through a direct effect on B- cells( Snapper and Paul, 1987). |
| cord-005393-rhji4io9 | IFN-? is also a potent stimulator of the expression of the Fc receptors for IgG immunoglobins on macrophages( Erbe et al., 1990). |
| cord-005393-rhji4io9 | IFN-? is also a powerful effector molecule of the inflammatory response( reviewed in Schreiber and Celada, 1985). |
| cord-005393-rhji4io9 | Interferon- gamma( IFN-?) was originally discovered by Wheelock( 1965) as an activity that interfered with viral replication. |
| cord-005393-rhji4io9 | Moreover, EAE can be transferred to naive animals using IFN-~,-secreting Tqymphocytes isolated from animals experiencing EAE( Zamvil and SteLnman, 1990), and a significant increase in the level of IFN-?, |
| cord-005393-rhji4io9 | Reversible inhibitory effects of interferon- y and tumouar necrosis factor- o: on oligodendroglial lineage cell proliferation and differentiation in vitro Molecular cloning and expression of the human interferon-? |
| cord-005393-rhji4io9 | Taken as a whole, these observations demonstrate that IFN-? can either directly or indirectly mediate many of the CNS pathological effects that are observed in disorders in which immune cell traffic in the CNS increases. |
| cord-005393-rhji4io9 | The IFN-? work in Brian Popko's laboratory has been supported by the National Institutes of Health( NIH) research grant ROI NS34939, and |
| cord-005393-rhji4io9 | The presence of Table 2 Effects of IFN-? on the CNS Disruption of myelination Exacerbation of reactive gliosis Disruption of the blood- brain barrier Recruitment of inflammatory cells from the periphery Induction of MHC expression Stimulation of macrophage/ microglial cells Disruption of cerebellar granule cell migration this cytokine in the CNS leads to an abundance of pathological effects, including decreased myelination, increased gliosis, disruption of blood- brain barrier func~ on, increased MHC expression, stimulation of macrophage/ microglial activation, and disruption of cerebellar granule cell migration. |
| cord-005393-rhji4io9 | production of interferon gamma and tumor necrosis factor precedes clinical manifestation in multiple sclerosis: do cytokines trigger off exacerbations? |
| cord-022659-chwk2bs4 | ( mean 2 standard error of mean) without U74500A and was reduced to 0.76? |
| cord-022659-chwk2bs4 | 36* 12 yr), and 17 normal controls( 8 male, 9 female; 3 1? 9 yr) on specific neuropsychological( NP) and computer- administered tasks of attentional ability. |
| cord-022659-chwk2bs4 | Differentiated from Alzheimer's Disease? |
| cord-022659-chwk2bs4 | Do these results suggest that whatever causes MS can be eradicated in half of the demyelinating areas by the time of death? |
| cord-022659-chwk2bs4 | Does deprenyl have a symptomatic effect on patients with untreated and L- dopa- treated Parkinson's disease( PD)? |
| cord-022659-chwk2bs4 | Helpers( T4) decreased from 1,436 in controls to 985 in migraine patients, and total?' |
| cord-022659-chwk2bs4 | K, of tumor- free brain was 1.40 to 2.69( mean 1.89? 0.50). |
| cord-022659-chwk2bs4 | Normals completed the battery in 297 i 56, and cognitively declined patients completed the battery in 359? |
| cord-022659-chwk2bs4 | Once deprenyl is started, how long is it before another medication is needed to control symptoms of continued disease progression? |
| cord-022659-chwk2bs4 | PMN- mediated myelin oxidation was 1.89_ t 0.44 without drug and 0.64? 0.10 with drug( p< 0.02). |
| cord-022659-chwk2bs4 | Polyneuropathy: A Chronic Inflammatory Demyelinating Polyradiculoneuropathy Variant? |
| cord-022659-chwk2bs4 | Six months later, 7/24( 29.2%) patients still had low thresholds but the mean MEP/ CMAP ratio had dropped to 24.9? |
| cord-022659-chwk2bs4 | To investigate the effects of lacunar infarction( LI) on cognitive function, we examined 57 LI patients 3 months after stroke( age= 71.6? |
| cord-022659-chwk2bs4 | Twenty were considered to be at increased risk(? 85%), 14 at decreased risk(< 15%), and in 1 individual no modification could be given. |
| cord-022659-chwk2bs4 | We report a married couple, both of Clue to Etiology? |
| cord-022659-chwk2bs4 | We therefore compared 17 TS patients( 9 male, 8 female; mean age 32? 11 yr), 17 ADHD patients( 8 male, 9 female; |
| cord-022659-chwk2bs4 | mean* SD, 0.94? 0.33 and 0.74 |
| cord-022659-chwk2bs4 | well 2 0.6 x lo5 cells; ceramide- treated cells grew to 1.6 X lo5? |
| cord-015352-2d02eq3y | Computed tomography: Are we doing enough? cord-015352-2d02eq3y A new integrated approach for the evaluation of fetal cerebral pathologies? cord-015352-2d02eq3y And why do we grow up so slowly and get so old? cord-015352-2d02eq3y Do ADC- values reflect renal function or obstruction in children with uretero- pelvic- junction obstruction? cord-015352-2d02eq3y Fluoroscopy in pediatric radiology-how important is an individual impact to radiation exposure of children? cord-015352-2d02eq3y Has everything been invented? cord-015352-2d02eq3y However, although the principles of these diagnostic and therapeutic IR procedures remain essentially the same in their translation from adults to children, well recognized differences in pediatric physiology and metabolism, as well as the range in weight, size, and age of children, result in a practical question ofhow do we do this? |
| cord-015352-2d02eq3y | If clinical examination is reliable and accurate, then why bother with imaging? |
| cord-015352-2d02eq3y | Is Sclerotherapy an Effective Treatment Option for Ranulas or Thyroglossal Duct Cysts in Children? |
| cord-015352-2d02eq3y | Is it surely Canavan Disease? |
| cord-015352-2d02eq3y | Lung ultrasound in pediatric pneumonia-why is it necessary to use the additional trans- abdominal approach? |
| cord-015352-2d02eq3y | Pre- and Postnatal Imaging in Zika virus: Where are we? |
| cord-015352-2d02eq3y | Real time central review of imaging is feasible in pediatric oncology Wilms tumor remains the most common pediatric renal malignancy, followed by renal cell carcinoma Cystic nephroma typically presents as a Bosniak 3 lesion, and has high association with DICER-1 mutations Is there a role for DWI in nephroblastoma? |
| cord-015352-2d02eq3y | The patient subsequently underwent a sonography which revealed a pelvic mass probably arising from the right ovary? |
| cord-015352-2d02eq3y | There is one fundamental challenge for imaging research in JIA: what is the reference standard? |
| cord-015352-2d02eq3y | Why are we born with brains that have the size of adult great ape brains? |
| cord-015352-2d02eq3y | and when? |
| cord-015352-2d02eq3y | it really as reliable as chest X- ray? |
| cord-015352-2d02eq3y | routinely satisfiable in a paediatric radiology division? |
| cord-257167-rz4r5sj7 | ( 1) Which type of brain infarction will be a future target of this therapeutic approach? |
| cord-257167-rz4r5sj7 | ( 2) Which phase of brain infarction( i.e., acute or chronic phase) will be selected as a future timing of therapeutic intervention? |
| cord-257167-rz4r5sj7 | ( 3) Which will be the best way to be applied in the clinical settings, neurogenesis control, stem cell supply or both? |
| cord-257167-rz4r5sj7 | Are NSF and VCP playing complementary or antagonistic roles? |
| cord-257167-rz4r5sj7 | How are brains controlled molecularly? |
| cord-257167-rz4r5sj7 | How can a material object became aware of the world around it and of its very own awareness? |
| cord-257167-rz4r5sj7 | How do pictorial cues influence 3D information processing in the parietal association cortex? |
| cord-257167-rz4r5sj7 | How do these neurons integrate signals from V1? |
| cord-257167-rz4r5sj7 | How do we deal with timing in the brain? |
| cord-257167-rz4r5sj7 | How do we determine what is good or bad for the maturing brain? |
| cord-257167-rz4r5sj7 | How does the brain order successive events? |
| cord-257167-rz4r5sj7 | How is olfactory receptor- dependent axonal wiring conducted? |
| cord-257167-rz4r5sj7 | How relevant is it in protein synthesis- dependent late- phase plasticity( LP)? |
| cord-257167-rz4r5sj7 | In particular, does the well- known columnar organization of V1 play a role in determining the shape selectivity of higher- order neurons? |
| cord-257167-rz4r5sj7 | It is open question, however, if the brain correctly compensates the difference of the relative position of eyes to the head? |
| cord-257167-rz4r5sj7 | JST.ERATO, HFSP SY2- 2- 08- 4 Why look there? |
| cord-257167-rz4r5sj7 | PS3P- G101 Is"seronegative"MG explained by autoantibodies to MuSK? |
| cord-257167-rz4r5sj7 | Thirty tasks were presented visually every 30 s, the subjects were asked to think about the question immediately following the sentences and asked not to think moreover if the question was difficult( e.g., How to cook curried rice? |
| cord-257167-rz4r5sj7 | This raises urgent and important ethical questions for our consideration: is there an"ideal"brain we should be nurturing? |
| cord-257167-rz4r5sj7 | To what extent can/ should drugs be used not merely to correct developmental disorders but also to enhance performance? |
| cord-257167-rz4r5sj7 | Which is essential? |
| cord-257167-rz4r5sj7 | Why do we look where we do? |
| cord-257167-rz4r5sj7 | or How to fold paper into a turtle? etc). |
| cord-026031-hnf5vayd | Any cleaning products used inside or outside the house within the last 48 hours? |
| cord-026031-hnf5vayd | Any construction work or renovation recently? |
| cord-026031-hnf5vayd | Any fertilizers or weed killer used in the last week? |
| cord-026031-hnf5vayd | Any mouse or rat poison in your house, yard, or garage? |
| cord-026031-hnf5vayd | Are there any abnormal postures? |
| cord-026031-hnf5vayd | Are there any characteristic odors on the breath? |
| cord-026031-hnf5vayd | Are there any other abnormal signs that you have seen? |
| cord-026031-hnf5vayd | Are there any pulse deficits or dysrhythmias auscultated? |
| cord-026031-hnf5vayd | Are there any traces of foreign material on the tongue or in the crevices of the teeth or gums? |
| cord-026031-hnf5vayd | Are there petechiae or ecchymosis on the gums or bleeding from the gumline? |
| cord-026031-hnf5vayd | Did the owner attempt any irrigation or medical techniques prior to presentation? |
| cord-026031-hnf5vayd | Did you give any medications to your animal? |
| cord-026031-hnf5vayd | Did you witness the ingestion or exposure? |
| cord-026031-hnf5vayd | Did your pet eat this morning or last night? |
| cord-026031-hnf5vayd | Do the intestinal loops feel normal, or are they fluid- filled or gas- filled? |
| cord-026031-hnf5vayd | Do you have any over- the- counter or prescription medications that your animal may have had access to? |
| cord-026031-hnf5vayd | Do you have the container with you today? |
| cord-026031-hnf5vayd | Do you hear harsh airway sounds or pulmonary crackles? |
| cord-026031-hnf5vayd | Do you observe any ptyalism or attempts to vomit? |
| cord-026031-hnf5vayd | Do you think that the signs have been the same, better, or getting worse? |
| cord-026031-hnf5vayd | Does it appear lethargic or hyperactive? |
| cord-026031-hnf5vayd | Does the animal have access to any poisonous substances? |
| cord-026031-hnf5vayd | Does your animal have access to any known toxins, or does he or she run loose unattended? |
| cord-026031-hnf5vayd | Does your animal have any ongoing or past medical problems? |
| cord-026031-hnf5vayd | Does your animal run loose outdoors unattended? |
| cord-026031-hnf5vayd | Does your pet have access to a compost pile? |
| cord-026031-hnf5vayd | Does your pet have access to neighboring properties( even for a short time)? |
| cord-026031-hnf5vayd | Does your pet run loose unattended? |
| cord-026031-hnf5vayd | For example, is the patient retaining bicarbonate( metabolic alkalosis) because of carbon dioxide retention( respiratory acidosis)? |
| cord-026031-hnf5vayd | Has it changed at all since the owner noticed the problem? |
| cord-026031-hnf5vayd | Has there been any gardening work recently? |
| cord-026031-hnf5vayd | Has there been any prior incident of ocular disease? |
| cord-026031-hnf5vayd | Has your animal been on any medications recently or currently? |
| cord-026031-hnf5vayd | Has your animal been vaccinated recently? |
| cord-026031-hnf5vayd | Has your animal had any previous or similar episodes? |
| cord-026031-hnf5vayd | Has your pet been off your property in the last 24- 48 hours? |
| cord-026031-hnf5vayd | Has your pet been to rural areas in the last week? |
| cord-026031-hnf5vayd | Has your pet had any antiflea/ tick medication within the last week?Your pet's environment Is your animal kept inside or outside of the house? |
| cord-026031-hnf5vayd | Has your pet traveled outside of your immediate geographic location? |
| cord-026031-hnf5vayd | Have any known relatives of your animal had any bleeding disorders? |
| cord-026031-hnf5vayd | Have similar signs occurred in the past? |
| cord-026031-hnf5vayd | Have the signs become better or worse since you first saw them? |
| cord-026031-hnf5vayd | Have you changed your radiator fluid or does a car leak antifreeze? |
| cord-026031-hnf5vayd | Have you fed table scraps or anything new recently? |
| cord-026031-hnf5vayd | How fast did the clinical signs develop? |
| cord-026031-hnf5vayd | How is the patient acting? |
| cord-026031-hnf5vayd | How long ago do you think that your pet was exposed to the poison? |
| cord-026031-hnf5vayd | How long ago was the exposure? |
| cord-026031-hnf5vayd | How long has the animal been acting that way? |
| cord-026031-hnf5vayd | How much did the animal consume? |
| cord-026031-hnf5vayd | How soon did other signs develop? |
| cord-026031-hnf5vayd | If so, what? |
| cord-026031-hnf5vayd | If so, when and how much did your animal consume? |
| cord-026031-hnf5vayd | If so, when? |
| cord-026031-hnf5vayd | If so, which? |
| cord-026031-hnf5vayd | Is abdominal palpation painful? |
| cord-026031-hnf5vayd | Is it a liquid concentrate, dilute spray, or solid? |
| cord-026031-hnf5vayd | Is it fast, normal, or slow? |
| cord-026031-hnf5vayd | Is it moist, dry, bubbling, or frothy, or caked with dirt? |
| cord-026031-hnf5vayd | Is it normal and pink, or dark red( injected), pale, or icteric? |
| cord-026031-hnf5vayd | Is it normal, fast, shallow, or labored? |
| cord-026031-hnf5vayd | Is it synchronous with the heart rate, or are there dropped pulses? |
| cord-026031-hnf5vayd | Is the animal ambulatory, and if so, do you observe any gait abnormalities? |
| cord-026031-hnf5vayd | Is the lens clear and is it in the normal position? |
| cord-026031-hnf5vayd | Is the ocular examination normal? |
| cord-026031-hnf5vayd | Is the pulse bounding, normal, thready, or not palpable? |
| cord-026031-hnf5vayd | Is there a P wave for every QRS, and a QRS for every P wave? |
| cord-026031-hnf5vayd | Is there a chance that your pet may have gotten into the garbage? |
| cord-026031-hnf5vayd | Is there a palpable urinary bladder? |
| cord-026031-hnf5vayd | Is there any history of trauma or known chemical irritant or exposure? |
| cord-026031-hnf5vayd | Is there any possibility of any toxin exposure? |
| cord-026031-hnf5vayd | Is there any possibility of trauma? |
| cord-026031-hnf5vayd | Is there any vomiting, diarrhea, trembling, or seizures? |
| cord-026031-hnf5vayd | Is there evidence of vomiting or diarrhea? |
| cord-026031-hnf5vayd | Is there excessive salivation? |
| cord-026031-hnf5vayd | Is there respiratory distress? |
| cord-026031-hnf5vayd | Is there urine production? |
| cord-026031-hnf5vayd | Is your animal able to walk? |
| cord-026031-hnf5vayd | Is your animal breathing or does it have respiratory difficulty? |
| cord-026031-hnf5vayd | Is your pet kept in a fenced- in yard or allowed to run loose unattended? |
| cord-026031-hnf5vayd | It is useful to phrase questions in a neutral fashion- for example,"Is such- and- such present on the premises?" |
| cord-026031-hnf5vayd | Was the substance swallowed, or is it on the animal's skin or eyes? |
| cord-026031-hnf5vayd | What clinical signs developed? |
| cord-026031-hnf5vayd | What do you hear on thoracic auscultation? |
| cord-026031-hnf5vayd | What is the animal's activity level? |
| cord-026031-hnf5vayd | What is the capillary refill time? |
| cord-026031-hnf5vayd | What is the color and consistency of the feces? |
| cord-026031-hnf5vayd | What is the color of the gums or tongue? |
| cord-026031-hnf5vayd | What is the color of the urine? |
| cord-026031-hnf5vayd | What is the mucous membrane color? |
| cord-026031-hnf5vayd | What is the name of the product? |
| cord-026031-hnf5vayd | What is the nature of the bleeding? |
| cord-026031-hnf5vayd | What is the patient's blood pressure? |
| cord-026031-hnf5vayd | What is the patient's electrocardiogram? |
| cord-026031-hnf5vayd | What is the patient's heart rate? |
| cord-026031-hnf5vayd | What is the patient's rectal temperature? |
| cord-026031-hnf5vayd | What is the patient's respiratory character? |
| cord-026031-hnf5vayd | What is the patient's respiratory rate? |
| cord-026031-hnf5vayd | What is the pupil reactivity to light? |
| cord-026031-hnf5vayd | What is the pupil size? |
| cord-026031-hnf5vayd | What is the quality of the femoral pulse? |
| cord-026031-hnf5vayd | What is the sensitivity to light or sound? |
| cord-026031-hnf5vayd | What is the substance that your animal ingested( was exposed to)? |
| cord-026031-hnf5vayd | What is your chief complaint or reason that you brought your animal in on emergency? |
| cord-026031-hnf5vayd | What other conditions have developed and what are they? |
| cord-026031-hnf5vayd | What sites are affected? |
| cord-026031-hnf5vayd | What was the first abnormal sign noticed? |
| cord-026031-hnf5vayd | When did the signs first start, or when was your animal last normal? |
| cord-026031-hnf5vayd | When did you first notice that something was wrong with your pet? |
| cord-026031-hnf5vayd | When was the animal last seen as normal? |
| cord-026031-hnf5vayd | When was the last time you noticed your pet act normally? |
| cord-026031-hnf5vayd | When was the onset of clinical signs? |
| cord-026031-hnf5vayd | When was the problem first noticed? |
| cord-026031-hnf5vayd | Where do you think it happened? |
| cord-026031-hnf5vayd | Where has your pet been in the last 24 hours? |
| cord-026031-hnf5vayd | if so, where? |
| cord-026031-hnf5vayd | or When was the last time you saw your animal act normally? |
| cord-026031-hnf5vayd | rather than"Could the dog have eaten such- and- such?" |
| cord-026031-hnf5vayd | she normally fed? |
| cord-026031-hnf5vayd | • How long has the bleeding been going on? |