trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram frequency
virsorter node length256
node length cov256
cat virsorter node241
acute respiratory syndrome232
severe acute respiratory231
in this study216
the presence of211
respiratory syndrome coronavirus192
as well as175
of a novel123
the number of114
based on the114
the role of109
east respiratory syndrome107
middle east respiratory106
closely related to103
due to the92
one of the92
a total of91
found to be85
according to the84
of emerging viruses84
in addition to82
the evolution of81
and characterization of81
a number of81
emerging infectious diseases80
coronaviruses in bats80
reservoir hosts of79
and bat cov79
characterization of a78
bats in the76
the emergence of76
of bats in76
of the bat75
was used to75
the absence of73
in bats from73
been detected in71
have been identified71
as reservoirs of69
in the same69
of severe acute69
genetic diversity of68
were detected in67
the risk of66
related to the66
a variety of66
of nipah virus64
analysis of the64
of these viruses63
of bats and63
virus infection in62
was detected in62
have been detected61
black flying fox60
it has been59
of bats to59
have also been59
in bats in58
species of bats58
big brown bats58
supplementary table s57
viruses in bats57
to determine the57
perivascular adipose tissue56
natural reservoirs of56
important reservoir hosts56
of the virus56
in the bat56
hosts of emerging55
bats and rodents54
in bats and54
bats have been54
different bat species53
are known to52
the detection of52
detected in the52
identification of a52
members of the52
human sars cov52
bat species in51
in order to51
associated with the50
the importance of50
the identification of50
of ebola virus50
in humans and49
to be the48
the prevalence of48
been identified in48
the majority of48
of hendra virus47
between bats and47
the discovery of47
consistent with the47
a novel coronavirus47
of zoonotic viruses47
drexler et al46
bats as reservoirs46
have been reported46
were collected from46
the origin of46
in response to45
that bats are45
identified in the45
is consistent with45
the ability of45
differences in the45
of coronaviruses in45
brown adipose tissue44
belonging to the44
of the sars43
most of the43
likely to be43
dependent rna polymerase43
viruses in the43
large number of43
was found to43
samples were collected42
of a bat42
of marburg virus42
in fruit bats42
bat paramyxovirus b42
the use of42
the ecology of42
isolation and characterization41
egyptian fruit bat41
egyptian fruit bats41
bats and their40
involved in the40
were identified in40
from bats to40
of the bats40
found in the39
bats as a39
in our study39
in the absence39
of the same39
been isolated from39
zhou et al39
are natural reservoirs38
of a new38
was isolated from38
phylogenetic analysis of38
been shown to37
infection in bats37
that have been37
been reported in37
belong to the37
in bat populations37
a large number37
bats are natural37
of rabies virus37
were found to37
to identify the37
a natural reservoir37
in the field37
detected in bats37
of the most37
natural reservoir of37
influenza a virus37
to be a37
like virus in37
appear to be36
the authors declare36
bats of the36
birds and bats36
known to be36
of bat origin36
to that of35
structure of the35
diversity of coronaviruses35
human parainfluenza virus35
bat coronavirus hku35
understanding of the34
fruit bats in34
in a bat34
there is a34
colored fruit bat34
this study was34
bats are the34
jamaican fruit bats34
for the presence34
some of the34
syndrome coronavirus in34
were obtained from34
reservoirs of sars34
in the united34
the study of34
in european bats34
in insectivorous bats34
the severe acute34
of the viruses33
of the family33
the development of33
of bat species33
influenza a viruses33
as shown in33
an important role33
from the same33
the lack of33
is associated with32
comparative analysis of32
fruit bats as32
has also been32
the effect of32
more likely to32
were able to32
european bat lyssavirus32
included in the32
has not been32
in terms of32
the expression of32
contact with bats32
in bats of32
the distribution of32
we found that31
in pteropid bats31
with respect to31
in bat species31
have been found31
the virus was31
isolation of a31
to the genus31
of the genus31
responsible for the31
important role in31
of human sars31
the nature of31
calisher et al31
were used to31
role of bats31
was performed using31
nipah virus infection30
reservoirs of ebola30
experimental infection of30
appears to be30
insights into the30
obtained from the30
has been reported30
is known about30
amino acid sequences30
as described previously30
chinese horseshoe bats30
a result of30
the natural reservoir30
were positive for30
the united states30
of the species30
the egyptian fruit29
were used for29
we did not29
little brown bat29
species of the29
risk factors for29
the present study29
may not be29
been found in29
was found in29
in saudi arabia29
role in the29
of bat coronaviruses29
detected in a29
and genetic diversity29
data not shown29
date palm sap29
is the first29
isolated from a29
bat coronaviruses in29
a role in29
part of the28
from bats in28
supplementary figure s28
present in the28
in the genus28
of bats as28
there was no28
a range of28
in accordance with28
the possibility of28
the bat paramyxovirus28
and evolution of28
by using the28
wide range of28
viruses have been28
little brown bats28
egyptian rousette bats28
coronavirus in bats28
all of the28
each of the27
in southern china27
the context of27
isolated from the27
rna was extracted27
a recent study27
the genomes of27
the bat species27
new world bats27
virus in the27
to assess the27
may be a27
are associated with27
of which are27
were found in27
of the immune27
the same species27
the results of27
in the context27
the transmission of27
of the world27
the immune response27
the black flying27
sequence of the27
the immune system26
as a result26
human and animal26
was used for26
a and b26
species in the26
the case of26
in the past26
was extracted from26
of bat cov26
the potential for26
a wide range26
of infectious diseases26
on the other26
bat species and26
woo et al26
the phylogenetic tree26
an increase in26
the regulation of26
to other mammals26
capable of infecting26
in other mammals26
found in bats26
the great leaf26
humans and other26
at room temperature25
in the s25
such as the25
implications for the25
conflict of interest25
the top end25
that of the25
disease in humans25
porcine epidemic diarrhea25
genome sequence of25
direct contact with25
genomic characterization of25
of human infection25
bats in china25
in north america25
been identified as25
identified in bats25
nipah virus from25
in bat cells25
as previously described25
the level of25
of the human25
have not been25
the amino acid25
multiple sequence alignment25
that bats may25
evolution of the25
as reservoirs for25
well as the24
shown to be24
bat cell lines24
approved by the24
type i ifn24
evidence for the24
compared to the24
be due to24
responses of bats24
revealed that the24
has been shown24
a review of24
the need for24
in chinese horseshoe24
all three viruses24
adipose tissue in24
and amino acid24
g p g24
infections in humans24
the diversity of24
with regard to24
the fact that24
the sars coronavirus24
associated with a24
that uses the23
region of the23
there is no23
close contact with23
of this virus23
we were able23
serological evidence of23
to investigate the23
is one of23
of emerging infectious23
thought to be23
ebola and marburg23
respiratory disease in23
of the novel23
virus in bats23
natural reservoir for23
number of viruses23
in bats is23
is important to23
other bat species23
be associated with23
little is known23
showed that the23
hendra and nipah23
a comparison of23
the induction of23
used as a23
reservoirs for emerging23
contact with humans23
p g rva23
isolated from bats23
the ace receptor22
none of the22
discovery of a22
white adipose tissue22
at the time22
characterization of the22
predicted to be22
ability of bats22
the range of22
many of the22
the proportion of22
uses the ace22
in recent years22
metagenomic analysis of22
that they have22
better understanding of22
the ability to22
human sars and22
the effects of22
coronaviruses in the22
of the viral22
we used the22
different species of22
luis et al22
been associated with22
lau et al22
source of emerging22
molecular evolutionary genetics22
a lack of22
similar to the22
the ifn response22
it is possible22
of bat viruses22
bats and the22
signs of disease22
are likely to22
bats to humans22
is possible that22
no evidence of22
remains to be22
diseases in humans22
addition to the22
end of the22
s and s22
and avian coronaviruses22
in close proximity22
play an important21
was carried out21
sequences of the21
virus in chinese21
no conflict of21
any of the21
hsp and hsp21
as reservoir hosts21
that there are21
with that of21
major mammalian paramyxoviruses21
in the wild21
and marburg viruses21
the possibility that21
that there is21
more than one21
of bats from21
are capable of21
are shown in21
evolutionary genetics analysis21
detection of a21
the other hand21
of the host21
of middle east21
australian bat lyssavirus21
chinese rufous horseshoe21
chua et al21
bats are a21
in the study21
shown in figure21
diversity of bat21
those of the21
compared to other21
host major mammalian21
for min at21
this is the21
of the rna21
protein of sars21
was observed in21
of covs in21
it should be20
infection of bats20
depending on the20
analysis of bat20
rna was detected20
origin of sars20
the order chiroptera20
for the first20
the control of20
are bats special20
colored fruit bats20
bat species from20
prevalence and genetic20
the australian black20
reservoirs of zoonotic20
human and bat20
there was a20
nipah virus in20
the hypothesis that20
the little brown20
it is not20
bats host major20
bats from china20
are the only20
human coronavirus e20
in contrast to20
most closely related20
it is important20
the activation of20
similar to that20
a better understanding20
pcr products were20
total number of20
host and viral20
the relationship between20
expression levels of20
the time of20
broad range of20
can be used20
a bat sars20
member of the20
was obtained from20
coronavirus that uses20
infectious diseases in20
the most important20
which is a20
and in the20
rufous horseshoe bat20
hepatitis b virus20
this study were20
an outbreak of20
to understand the20
viruses of the20
considered to be20
in all three20
bats may have20
have been described20
australian black flying20
rodents and bats20
with the exception20
hendra virus infection20
care and use20
like coronavirus that20
immune responses of20
authors declare no20
and rodents as19
and nipah viruses19
of the manuscript19
the fossil record19
o u r19
of novel viruses19
week treatment with19
with those of19
for detection of19
to the same19
to other species19
of group coronaviruses19
fruit bat cells19
with severe acute19
r n a19
amino acid identity19
due to their19
of zika virus19
the potential to19
in relation to19
of influenza a19
the impact of19
corman et al19
of this study19
some bat species19
reservoir hosts for19
to determine whether19
rodents as reservoirs19
u r n19
the first time19
j o u19
for the origin19
human and mouse19
bats may be19
a new species19
li et al19
to those of19
animals and humans19
large flying fox19
for the study19
of human coronavirus19
the production of19
have been shown19
distantly related to19
p r e19
the genetic diversity19
the ministry of19
molecular characterization of19
plowright et al19
to have a19
treatment with either19
n a l19
bat aav capsid19
insight into the19
the genome of19
of viruses in19
a l p19
as the gene19
the exception of19
democratic republic of19
around the world19
the united kingdom19
in bat and19
used for the19
from pteropid bats19
for statistical computing19
in contact with19
but not in19
sequence identity with19
bat lyssavirus type19
shown in fig19
a novel bat18
the middle east18
changes in the18
observed in the18
the existence of18
in which the18
our understanding of18
play a role18
has been isolated18
novel mammalian viruses18
has been detected18
virus infections in18
there have been18
species of bat18
may have been18
with either vehicle18
evolutionary history of18
l p r18
of which were18
of the disease18
group coronaviruses in18
have been isolated18
collected from the18
coronaviruses as the18
epidemic diarrhea virus18
gene source of18
been described in18
of european bat18
vehicle or indirubin18
type iii ifn18
de novo assembly18
o o f18
bats and birds18
all of which18
the innate immune18
thermo fisher scientific18
increase in the18
of the s18
the university of18
bats captured in18
were constructed using18
bats were captured18
japanese encephalitis virus18
been reported to18
bats and humans18
a broad range18
importance of bats18
the rate of18
known about the18
of genetically diverse18
a consequence of18
human infection with18
r o o18
available in the18
either vehicle or18
as a consequence18
and phylogenetic analysis18
the gene source18
were included in18
big brown bat18
to evaluate the18
of the genome18
are thought to18
p r o18
the human population18
bat species that18
from egyptian fruit18
be used to18
hendra virus from18
bats and other18
leroy et al18
identified in this17
covs in bats17
bats of different17
virus from pteropid17
has been suggested17
also known as17
niv and marv17
this suggests that17
viruses from bats17
in the new17
diversity of covs17
which is the17
jamaican fruit bat17
from this study17
evidence for a17
and stored at17
were performed in17
zhang et al17
in different bat17
referred to as17
detection of novel17
of bat rabies17
infections in bats17
comparison of bats17
viruses related to17
is closely related17
to better understand17
amino acid sequence17
insectivorous bats in17
the egyptian rousette17
to study the17
the same bat17
and classification of17
reservoirs for a17
to the family17
was added to17
of bats with17
the probability of17
innate and adaptive17
north american bat17
immunity in bats17
animal care and17
of the egyptian17
fruit bat species17
the new world17
the complete genome17
of all three17
novel coronavirus in17
the bat transcriptome17
interpretation of data17
because of the17
are found in17
to the bat17
genes involved in17
bat cov are17
based on a17
the course of17
bat coronaviruses and17
transmission to humans17
of adipose tissue17
that the virus17
of the year17
bat fecal samples17
for disease control17
host range and17
in the present17
taxonomy of viruses17
north american bats17
viruses belonging to17
the s gene17
immune response in17
in antiviral immunity17
more closely related17
of the study17
the chinese rufous17
as a reservoir17
european bat species17
west nile virus17
and use committee17
complete genome sequence17
and the bat17
a molecular phylogeny16
genome sequences of16
was associated with16
european bat lyssaviruses16
responses in bats16
genes in the16
regulation of the16
of the four16
of the samples16
been found to16
of different species16
is thought to16
emerging zoonotic viruses16
was used as16
identification and characterization16
majority of the16
clinical signs of16
genetically diverse marburg16
and p mapk16
in the transmission16
are susceptible to16
bats and viruses16
with more than16
ge et al16
identification of the16
these viruses are16
cov gc gc16
two species of16
bats illuminates biogeography16
of fruit bats16
shown in table16
been linked to16
found to have16
and the fossil16
authors declare that16
mammalian and avian16
for nipah virus16
trees were constructed16
belongs to the16
virus from malaysian16
a and a16
mhc class i16
a group of16
type iii ifns16
were tested for16
isolation of genetically16
to be determined16
is likely to16
in other species16
in the case16
positive selection in16
from malaysian island16
few studies have16
isolation of hendra16
bat species are16
phylogeny for bats16
susceptible to infection16
tong et al16
in the presence16
sequencing of the16
length cov gc16
the rest of16
mice under hfd16
reservoir of hendra16
sequence identity to16
viruses from egyptian16
close proximity to16
sars and bat16
bats are known16
have been used16
declare no conflict16
are consistent with16
of perivascular adipose16
bats from the16
emergence of sars16
diverse marburg viruses16
viruses such as16
marburg viruses from16
into the eu16
the current study16
as part of16
population genetic structure16
in rousettus aegyptiacus16
biogeography and the16
in line with16
the conservation of16
derived from the16
were performed using16
to humans and16
related viruses in16
prior to the16
innate immune response16
of humans and16
associated with an16
molecular phylogeny for16
associated with bats16
discovery of novel16
the orf protein16
the vast majority16
of hsp and16
aav capsid genes16
in dromedary camels16
for bats illuminates16
are needed to16
was identified in16
illuminates biogeography and16
isolation of nipah16
risk of human16
transmission of viruses15
contribute to the15
several bat species15
results suggest that15
to each other15
led to the15
effect of pvat15
the generation of15
the international committee15
rousettus aegyptiacus bats15
both of which15
the closely related15
declare that they15
in viet nam15
of sars coronavirus15
international committee on15
which have been15
yet to be15
polymerase chain reaction15
of bat irf15
million years ago15
nucleotide sequences of15
world health organization15
was performed in15
bat and human15
the most common15
bats to other15
virus in a15
there are no15
are closely related15
covs have been15
in bats may15
to our knowledge15
in the top15
in new world15
related to sars15
than that of15
the s protein15
evolution of flight15
natural reservoirs for15
are involved in15
the intrinsic disorder15
it was found15
diversity of viruses15
be susceptible to15
proteins of sars15
to the sars15
in close contact15
old world fruit15
rabies virus in15
the end of15
tested positive for15
identification of novel15
these viruses in15
accordance with the15
within the same15
of the protein15
has been identified15
rna polymerase gene15
for the bat15
identified as the15
to the eu15
at least one15
emergent deadly paramyxovirus15
the sequences of15
z at dpi15
viruses that have15
world fruit bats15
malaysian island flying15
to the human15
the bat aav15
infection in the15
constructed using the15
the isolation of15
nsp s from15
of bat and15
have demonstrated that15
like coronaviruses in15
of the rdrp15
the old world15
the source of15
several studies have15
the rdrp gene15
equine encephalitis virus15
republic of china15
review of the15
are able to15
american bat species15
of flight and15
revealed the presence15
and interpretation of15
were collected in15
should be noted15
and hendra virus15
of human and15
from the bat15
in the black15
low levels of15
positive for cov15
borna disease virus15
found that the15
marburg virus infection15
experimental inoculation of15
found in a14
was based on14
i coronaviruses in14
information on the14
h t cells14
it is also14
phylogenetic trees were14
group of mammals14
cell lines from14
into the evolution14
a continuing source14
and other coronaviruses14
their ability to14
and found that14
fragment of the14
antiviral immunity in14
will be required14
species within the14
the occurrence of14
nucleotide sequence identity14
viruses and the14
to infect humans14
and zoonotic viruses14
and prevalence patterns14
from patients with14
they have no14
novel paramyxoviruses in14
did not detect14
demonstrated that the14
the type i14
continuing source of14
nature of the14
hatten et al14
relatives of human14
rest of the14
bat influenza a14
to be present14
and their hosts14
evidence of a14
coronavirus associated with14
that may be14
natural reservoir host14
vero e cells14
both bats and14
vast majority of14
with zoonotic potential14
prevalence patterns of14
comparison of the14
the likelihood of14
are the most14
not yet been14
were associated with14
associated with bat14
the jamaican fruit14
regions of the14
crystal structure of14
emerging viruses in14
well as in14
bat origin of14
in the last14
detection and prevalence14
in bat guano14
be required to14
were present in14
blood samples were14
the natural reservoirs14
chu et al14
studies of the14
emerg infect dis14
and orf b14
in vampire bats14
four species of14
data suggest that14
was extracted using14
an important source14
because of their14
and in vivo14
supported by the14
a bat colony14
the samples were14
the nucleotide sequences14
and diversity of14
zoonotic transmission of14
leading to the14
s rrna gene14
committee on taxonomy14
on the basis14
the percentage of14
are important for14
performed using the14
a wide variety14
were obtained by14
and complete genome14
in bats have14
morbidity and mortality14
from fruit bats14
a source of14
are predicted to14
c h t14
from human sars14
to infection by14
have shown that14
and incubated for14
disease control and14
of intrinsic disorder14
acute respiratory disease14
used in the14
patterns of group14
humans and animals14
of a single14
on taxonomy of14
quan et al14
rabies virus and14
were approved by14
he et al14
and other mammals14
in human sars14
to examine the14
origin of the14
wide variety of14
were carried out14
are responsible for14
of the two14
mice fed ncd14
study was conducted14
higher levels of14
the basis of14
group i coronaviruses14
the family paramyxoviridae14
bat species with14
bats in north13
for a large13
and human health13
the virus to13
the total number13
of bat covs13
were also identified13
in birds and13
emerging infections in13
viral infections in13
samples from bats13
iucn red list13
ncd or hfd13
bats in europe13
viruses that are13
republic of congo13
viruses in a13
and human parainfluenza13
bats has been13
well as a13
at the same13
to be of13
of positive selection13
and have been13
in the americas13
has been proposed13
evidence that bats13
were stored at13
in bats are13
in human and13
was conducted in13
that indirubin treatment13
in old world13
open reading frames13
between the two13
sequences in the13
control and prevention13
borne zoonotic dis13
high prevalence of13
of big brown13
suggest that the13
was removed and13
data collection and13
to be more13
of group i13
and public health13
provided by bats13
seem to be13
bat contact and13
used in this13
institutional animal care13
orf b protein13
g for min13
of virus transmission13
the last years13
mapped to the13
recently emergent deadly13
is responsible for13
virus antibodies in13
nosed bat and13
not detected in13
also detected in13
of a large13
may lead to13
immune response to13
been used to13
virus has been13
could be a13
for hendra virus13
we used a13
seems to be13
to human and13
the form of13
by morfchibi web13
the vampire bat13
is involved in13
be noted that13
is an important13
has been found13
resulted in a13
as a continuing13
and transmission of13
only a few13
their zoonotic potential13
and supplementary table13
of the major13
in the future13
many bat species13
of viruses from13
and identification of13
originated from bats13
of the orf13
pathogens such as13
were isolated from13
pcr was performed13
among the most13
many of which13
can lead to13
and approved the13
of novel bat13
of north american13
from bats and13
these results suggest13
from other mammals13
is capable of13
chen et al13
appears to have13
suggests that the13
of emerging infections13
in the form13
the final manuscript13
a recently emergent13
factors associated with13
in china and13
within the genus13
with the bat13
of bat cells13
high levels of13
like and other13
bats from kenya13
suggested that the13
zoonotic potential of13
been implicated in13
fed ncd or13
with human sars13
genes related to13
potential risk of13
the same region13
the significance of13
ecosystem services provided13
immune responses in13
associated with severe13
a combination of13
in the human13
services provided by13
approved the final12
the phylogenetic analysis12
in yunnan province12
known to cause12
of more than12
of death in12
in the genomes12
bat populations in12
to human health12
species transmission of12
the loss of12
from bats of12
of the ifn12
in big brown12
and nipah virus12
horses and humans12
viruses and their12
bats compared to12
marburg virus in12
would like to12
and fruit bats12
isolated from fruit12
at the site12
presence of a12
the susceptibility of12
with acute respiratory12
of emerging zoonotic12
are among the12
experimental infections of12
in emerging infectious12
light on the12
emerging and reemerging12
viral infection in12
more than of12
adipose tissue and12
sympathetic nervous system12
social network analysis12
dna was extracted12
have been linked12
in the family12
of the total12
the only mammals12
part of a12
for phylogenetic analysis12
for cov rna12
the abundance of12
to viral infection12
yang et al12
feline infectious peritonitis12
which has been12
need to be12
of viruses and12
close to the12
in the region12
used to identify12
of viruses that12
stranded rna viruses12
or hfd after12
identified as a12
in a common12
in rodents and12
were similar to12
of novel sars12
were observed in12
in this region12
at least in12
life history traits12
number of species12
compared with the12
also identified in12
the degree of12
south american bats12
borne virus infections12
is shown in12
of viral infection12
to have been12
was first isolated12
bat species were12
viral diversity in12
the cause of12
is needed to12
domestic animals and12
the causative agent12
of irf in12
did not show12
may be the12
some of these12
in europe and12
sequences of bat12
out of the12
belonged to the12
high diversity of12
and there is12
amplification of emerging12
of viruses to12
anthony et al12
been demonstrated to12
identified from the12
the hb capsid12
the frequency of12
a history of12
true vs false12
of bats are12
of human coronaviruses12
it would be12
as a natural12
like to thank12
of the congo12
multiple bat species12
the extent of12
type i interferon12
be found in12
halpin et al12
in peninsular malaysia12
sequence identity of12
of viral rna12
vp and vp12
located in the12
centers for disease12
for emerging viruses12
are more likely12
the fruit bat12
in the immune12
the emergence and12
the most recent12
and sequencing of12
group c betacoronavirus12
open reading frame12
table s and12
coronaviruses in south12
analysis and interpretation12
flight and immunity12
is present in12
bats and bat12
the evolutionary history12
ucp expression and12
in the regulation12
bat viruses and12
deduced amino acid12
in the laboratory12
the zoonotic potential12
may have a12
and the evolution12
support in the12
and the chinese12
in the number12
the same genotype12
carried out in12
binding residues in12
of pvat in12
insectivorous bat species12
analysis was performed12
of public health12
molecular evolution of12
parts of the12
egyptian rousette bat12
for emerging zoonotic12
close relative of12
between bat and12
have been implicated12
reservoir host for12
phylogenetic tree of12
for human consumption12
studies have demonstrated12
result in the12
african fruit bat12
are listed in12
to be susceptible12
to explore the12
in the genome12
of bat sars12
the pathogenesis of12
study of the12
important source of12
in african straw12
tang et al12
infectious bronchitis virus12
as a potential12
experiments were performed12
be present in12
resulted in the12
total rna was12
of all mammalian12
was performed on12
of type i12
of insectivorous bats12
a novel betacoronavirus12
of human rabies12
infect dis doi12
was supported by12
the amount of12
cov rna was11
mhc class ii11
bats have a11
fecal samples were11
natural history of11
the e protein11
bat and the11
evidence of infection11
transmissible gastroenteritis virus11
number of zoonotic11
are the natural11
and viral traits11
z and aj11
studies of arthropod11
emerging zoonotic pathogens11
antiviral immune responses11
in this species11
relationships between the11
molecular characterisation of11
were determined by11
in southeast asia11
by a bat11
be closely related11
avian coronaviruses in11
may result in11
headed flying foxes11
replication and shedding11
bat genomes provides11
in south korea11
animal and human11
and domestic animals11
of infecting humans11
an acute respiratory11
the same study11
genetic structure of11
in humans or11
language and environment11
zoonotic infectious diseases11
bats are not11
the virus is11
and bat consumption11
there is evidence11
detection and characterization11
serve as a11
primers were designed11
in the brain11
a previous study11
the second most11
they do not11
genomes provides insight11
the host species11
were subjected to11
there is little11
to bind to11
this could be11
may play a11
characteristics of the11
of disease in11
we report the11
assigned to the11
was found that11
species have been11
of birds and11
to bats and11
of the order11
other coronaviruses in11
for bats as11
and it is11
is essential for11
encephalitis virus in11
in their natural11
and other species11
coronavirus in bat11
which may be11
in association with11
has been demonstrated11
c for min11
expressed in the11
detection of coronaviruses11
that it is11
of bat guano11
geographical distribution of11
bat cov hku11
the new bat11
biodiversity and mitochondrial11
these two viruses11
innate immune system11
was shown to11
in combination with11
species isolated from11
caused by a11
are grateful to11
were used in11
provides insight into11
first report of11
is required to11
there is an11
the first report11
bat cov nsp11
role of the11
results of the11
were collected and11
we review the11
republic of the11
the need to11
have recently been11
webber et al11
in the aftermath11
in jamaican fruit11
the pteropid bat11
transmission from bats11
a new genus11
expression in bats11
occurred in the11
of fruit bat11
viruses with zoonotic11
not appear to11
also been reported11
hepatitis c virus11
the release of11
of the sequences11
old world bats11
reported eating bats11
in previous studies11
to contribute to11
to be highly11
and environment for11
dn ds ratio11
based on these11
virus from bats11
virus isolated from11
better understand the11
that bats have11
of three novel11
supplementary table and11
cov and mers11
of bat genomes11
distribution of the11
of rna viruses11
in south africa11
and mitochondrial function11
to act as11
in the vicinity11
all authors read11
appeared to be11
database of bat11
the past months11
of human middle11
we found no11
in comparison to11
collected in the11
time course study11
may be due11
infections in chiroptera11
a and orf11
diverse group of11
to be associated11
the mrna expression11
sequences were aligned11
sequence of a11
functional analysis of11
a language and11
browning of swat11
analysis revealed that11
viral nucleic acid11
the implications of11
the aftermath of11
were shown to11
has not yet11
to coexist with11
total of samples11
of zoonotic diseases11
in the common11
no competing interests11
in the middle11
which is consistent11
bat and rodent11
acid sequences of11
the big brown11
as described above11
coronavirus infection in11
during the last11
for each of11
molecular diversity of11
common ancestor of11
bats as the11
gammacoronavirus and deltacoronavirus11
constitutive expression of11
is not a11
in other bat11
msa of sars11
nk cell receptors11
there may be11
for virus isolation11
and molecular characterization11
orf protein of11
is known to11
consistent with a11
were unable to11
and has been11
at the level11
host species and11
the republic of11
of other mammals11
the numbers of11
to the presence11
orf a and11
the origin and11
origin of human11
it is likely11
human middle east11
trends in emerging11
can be found11
on the island11
relative of human11
be explained by11
identical to the11
and the emergence11
of all the11
to reduce the11
most recent common11
in horseshoe bats11
the large flying11
bat rva strains11
difference in the11
han et al11
during the period11
most of these11
these data suggest11
interspecies transmission of11
were collected at11
dna binding residues11
in the eu11
is the most11
of infection in11
viruses capable of11
in some cases11
of these bat11
in both the11
causes of death11
hek t cells11
is found to11
of mice fed11
species and the11
zoonotic viruses in11
in asia and11
a previously unknown11
of viral infections11
and for the11
of rabies in11
cytochrome b gene11
in the current11
a bat bite11
adaptive immune response11
and experimental infection11
read and approved11
in west africa11
increased risk of11
followed by a11
global trends in11
acute diarrhoea syndrome11
to the laboratory11
variety of viruses11
amino acid level11
these viruses have11
threat to human11
and the potential11
are a major10
maps and institutional10
studies of bat10
of a number10
emergence of new10
has led to10
was performed with10
there are a10
of the ecology10
virus infection of10
in the hb10
activity in bat10
the genus alphacoronavirus10
detection of group10
compared with other10
that can be10
jones et al10
is the only10
in our datasets10
contributing to the10
of pvat on10
to jurisdictional claims10
in vitro and10
chakraborty and chakravarty10
from bat fecal10
diverse range of10
close relatives of10
of the pcr10
should not be10
of the type10
lyssavirus infection in10
that of other10
the wuhan sequence10
the purpose of10
the subgenus megatrypanum10
samples collected from10
from animals in10
the species of10
evolutionary relationships between10
not known to10
virus was first10
that did not10
results in the10
diversity in bats10
in pigs in10
in bats that10
the yn capsid10
african bat species10
the spike protein10
the formation of10
along with the10
reported to be10
jurisdictional claims in10
viral replication in10
in fruit bat10
we show that10
environment for statistical10
samples were then10
the same virus10
related to bat10
be responsible for10
all other tissues10
is clear that10
the biology of10
characterization of viruses10
the bat network10
fischer et al10
novel viruses in10
could also be10
the cells were10
and future directions10
seasonal pulses of10
bats appear to10
and bats are10
been described previously10
the treatment of10
bat species have10
it is clear10
contrast to the10
of nk cell10
that has been10
was confirmed by10
in more than10
in the environment10
the difference in10
was collected from10
zoonotic spillover from10
the bat virome10
living in close10
ray crystal structure10
are presented as10
bat activity and10
mutations in the10
other mammalian species10
nsp and nsp10
infection detected in10
no evidence for10
confirmed that the10
the dn ds10
were involved in10
predict zoonotic spillover10
rabies surveillance in10
of up to10
provide evidence for10
have no competing10
s from sars10
cell lines were10
and characterisation of10
virus was isolated10
other tissues were10
listed in table10
using mist nets10
a diverse range10
of the genera10
published maps and10
may also be10
bat in the10
study showed that10
indicated that the10
the phylogeny of10
of frugivorous bats10
sars coronavirus from10
of influenza viruses10
nature remains neutral10
protein from sars10
immune systems of10
in hong kong10
bats coincide with10
the reservoir hosts10
knowledge and future10
to emerging infectious10
of viral sharing10
sequence analysis of10
samples were tested10
from the black10
sites in the10
the adaptive immune10
common african bat10
of at least10
in this area10
bats are also10
claims in published10
into the ecology10
indirect immunofluorescence assay10
known to have10
complete genome sequences10
of emerging bat10
have been associated10
vitro and in10
from a bat10
has recently been10
the second largest10
genetic characterization of10
of interspecies transmission10
nucleotide and amino10
some of which10
iii ifn receptor10
coronavirus of bat10
and ecology of10
ebola virus disease10
the cytochrome b10
of bat immunology10
conservation of bats10
rna viruses in10
the outbreak of10
plos one doi10
genetic relatedness of10
bat cov and10
as the reservoir10
virus infection detected10
many of these10
of the innate10
venezuelan equine encephalitis10
pka and p10
the department of10
submitted to the10
world bat species10
human sars nsp10
from naturally infected10
the availability of10
in the population10
in these bats10
a high prevalence10
in bat of10
to nipah virus10
the orf of10
were used as10
roles in the10
sequencing was performed10
red list of10
we do not10
of the families10
disease in bats10
and do not10
during the past10
the species barrier10
range of viruses10
and severe acute10
of african straw10
human cell lines10
of pteropid bat10
gene repertoire of10
have examined the10
were visualized using10
a common ancestor10
should be considered10
the host range10
in the phylogenetic10
coronavirus hku strain10
large numbers of10
pteropid bat cell10
in experimentally infected10
is difficult to10
reovirus of bat10
spillover from mammals10
analyses were performed10
traits predict zoonotic10
reservoirs of emerging10
studies have examined10
risk of bat10
springer nature remains10
h n influenza10
a and supplementary10
transmitted to humans10
there has been10
of or genes10
emerging and re10
bats in a10
bat cells and10
evidence suggests that10
that the bat10
a novel paramyxovirus10
vector borne zoonotic10
and the presence10
it can be10
the most abundant10
regard to jurisdictional10
overview of the10
an insectivorous bat10
dna and rna10
novel bat coronaviruses10
strongly associated with10
to confirm the10
bat virus spillover10
known to infect10
response to the10
genes associated with10
coronaviruses have been10
in pigs and10
from each bat10
order of mammals10
and resulted in10
risks associated with10
of viruses with10
expression of the10
could not be10
coronavirus from a10
higher than the10
been suggested that10
receptors in the10
positive samples were10
compared to human10
bats identification of10
viral traits predict10
was performed by10
to public health10
obtained in this10
to determine if10
as viral reservoirs10
of wild animals10
there were no10
of a variety10
of powered flight10
genetic diversity and10
in liquid nitrogen10
current knowledge and10
be used as10
the iucn red10
circulating in the10
detected in this10
swine acute diarrhoea10
the database of10
of this article10
the elevation of10
hypothesis for the10
of other species10
orf of sars10
related to those10
bat lyssavirus in10
assessment of the10
in patients with10
of nsp s10
share a common10
neutral with regard10
extracted from the10
humans and mice10
intrinsic disorder in10
domain of the10
as described in10
a new virus10
in published maps10
in the world10
those of other10
viruses identified in10
a series of10
treated mice under10
a common african10
be a potential10
human transmission of10
the vicinity of10
the influence of10
in the orf10
at the end10
in this work10
genetics analysis version10
according to our10
contractile effect of10
for the control10
in the p10
the serum of10
remains neutral with10
and institutional affiliations10
as for the10
of alphacoronavirus and10
period of time10
of other bat10
were determined using10
of the lyssavirus10
echolocation in bats10
in bats has10
to have the10
of infected bats10
roosting in the10
of bats have10
studies have been10
and emergence of9
vascular smooth muscle9
great genetic diversity9
both human and9
of pteropid bats9
related to human9
isolated from bat9
has shown that9
causative agent of9
not associated with9
provided by the9
and ebola virus9
bats can be9
authors read and9
like viruses in9
ion torrent sequencing9
the maintenance of9
of the three9
to the order9
a reservoir for9
zoonotic viruses that9
level of the9
studies have shown9
t cell mediated9
decaro et al9
version of this9
it was observed9
an important reservoir9
public health and9
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classification of bat9
study was to9
of the respondents9
and the caribbean9
of infection and9
as a model9
other species of9
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to account for9
analysis based on9
three species of9
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evolutionary insights into9
and north america9
borne zoonotic viruses9
of viral metagenomics9
the dynamics of9
a high seroprevalence9
stored at uc9
novel mammalian and9
in costa rica9
tissue distribution of9
the control group9
periods of increased9
many novel viruses9
bat aav hb9
size of the9
of bat populations9
and a high9
of brown adipose9
in the emergence9
is characterized by9
dependent on the9
of the cytochrome9
virus was detected9
of niv in9
with periods of9
de novo transcriptome9
in the northern9
followed by cycles9
bat influenza virus9
to a bat9
coronavirus from animals9
of these species9
of exposure to9
alphacoronavirus and betacoronavirus9
what links bats9
the study and9
and other lyssaviruses9
as natural reservoirs9
hepatitis g virus9
be attributed to9
be able to9
focused on the9
response of bats9
the death of9
the l gene9
two of the9
was predicted to9
covs detected in9
new south wales9
reported in the9
coronavirus in european9
risk of infection9
with a high9
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the lyssavirus genus9
diseases in bats9
susceptibility of bats9
huang et al9
of this species9
reservoir host of9
and adaptive immune9
the study was9
virus and hendra9
a measure of9
was detected by9
a threat to9
in bat cov9
the activity of9
the consumption of9
s and supplementary9
the sars outbreak9
have been demonstrated9
genomic dna was9
the genus deltacoronavirus9
these viruses to9
i ifn locus9
in the host9
rabies in the9
unknown reovirus of9
of two novel9
based on partial9
disease in pigs9
the spread of9
fruit bats from9
origin is associated9
at the n9
presence of the9
the result of9
originated in bats9
alignment of the9
have the potential9
case fatality rate9
with humans and9
i and ii9
coronavirus e in9
the same cave9
were discovered in9
of these novel9
variation in the9
and mortality in9
of the n9
coexist with viruses9
included in this9
bat coronaviruses as9
structure and function9
ng et al9
bat consumption behaviors9
of gammacoronavirus and9
influenza d virus9
and nutritional stress9
of viruses related9
systems of bats9
the epidemiology of9
previously unknown reovirus9
bat contact experiences9
of the genes9
foundation for statistical9
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with an acute9
and marburg virus9
kepler et al9
mean ppids of9
in the n9
this work was9
that they are9
possible that the9
this study and9
over the past9
of the subgenus9
in human cells9
of the authors9
of threatened species9
bats living in9
and betacoronavirus and9
within roost type9
other members of9
terminal region of9
pteropus giganteus bats9
in this review9
bats to emerging9
limited number of9
rna and dna9
identified in a9
for min and9
the proposed genus9
experimentally inoculated with9
the roles of9
the recognition of9
of potentially zoonotic9
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links bats to9
studies indicated that9
virome diversity in9
virus isolation of9
diversity of the9
the potential of9
aegyptiacus bats coincide9
viral rna in9
and causes of9
dynamics in bats9
of increased risk9
source of gammacoronavirus9
a limited number9
transmission of sars9
serologic evidence of9
european bats and9
juvenile rousettus aegyptiacus9
plays an important9
detection and phylogenetic9
the sars epidemic9
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the circulation of9
indicated by the9
pcr assays to9
ecology of bats9
a summary of9
in the database9
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nipah and hendra9
in figure a9
severe emerging infectious9
of zoonotic infectious9
from a man9
avian coronaviruses as9
the increase in9
the potential risk9
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there are many9
bat lyssavirus infection9
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fatal disease in9
antibodies in bats9
of viral replication9
activated protein kinase9
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a new member9
not be the9
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region of cameroon9
species that are9
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conserved region of9
the genome sequences9
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the virus in9
of host species9
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tumor necrosis factor9
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less than years9
characterization of nipah9
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high seroprevalence of9
cov ratg and9
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this study is9
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the function of9
positive and negative9
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emergence of zoonotic9
source of alphacoronavirus9
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viruses in humans9
between bat species9
for the great9
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human cases of9
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of immune genes9
japanese b encephalitis9
interest in bat9
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deltacoronavirus supports bat9
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disease in horses9
at swarming sites9
the indian flying9
under the following9
to note that9
for each gene9
towner et al9
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virus circulation in9
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betacoronavirus and avian9
was not detected9
r foundation for9
binding to the9
in the central9
protein binding regions9
pathogenic leptospira spp9
irf in the9
be involved in9
known to harbor9
is likely that9
the genus rhinolophus9
a highly diverse9
indian flying fox9
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all bats were9
results showed that9
experimentally infected with9
of seven novel9
to suggest that9
ecology and evolution9
bat species can9
rhinolophus bat coronavirus9
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appear to have9
the democratic republic9
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attributed to the9
the bat ifn9
as the primary9
reservoirs of a9
room temperature for9
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report of the9
experimental nipah virus9
identified in our9
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infection in humans9
discovery of seven9
novel coronavirus from9
innate immune responses9
bat origin is9
viruses to humans9
was performed to9
bats are considered9
the rhinolophoid bats9
bat species of9
genus deltacoronavirus supports9
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range of pathogens9
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cov nsp proteins9
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of the coronavirus9
a severe acute9
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of mers coronavirus9
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ecology of coronaviruses9
in little brown9
infection with a9
johnson et al9
little red flying9
mammalian viruses in9
bat activation and9
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animals in southern9
list of threatened9
key role in9
genbank accession number9
by the presence9
in supplementary table9
coronaviruses and experimental9
that belong to9
the online version9
was closely related9
and control of8
due to its8
were assigned to8
macrophage marker f8
bats could be8
in wild birds8
the thymus and8
marburg virus circulation8
elevation of the8
for more details8
nipah virus encephalitis8
cells in bats8
number of other8
that could be8
factors for human8
in the community8
relatives of severe8
provide insight into8
this protein is8
in this setting8
at dpi had8
activity of the8
of all known8
were also found8
has implications for8
an intermediate host8
was detected from8
for the detection8
fecal samples reveals8
of the paramyxoviridae8
into two suborders8
between different bat8
restricted to the8
in a new8
hku strain hku8
viruses that can8
and can be8
of the other8
disease in a8
with nsp of8
c bl mice8
in the literature8
nine bat species8
for this study8
this has been8
infection has been8
predicted to have8
were aligned using8
length cov id8
immortalisation and characterisation8
were calculated using8