Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-000389-9vnthmfnNatural regulatory T cells in infectious disease Regulatory T cells: friend or foe in immunity to infection?
cord-031316-yvid6qpsDomestic pigs in Africa Risk factors for African swine fever in smallholder pig production Systems in Uganda Role of wild suids in the epidemiology of African swine fever History of"swine fever"in Southern Africa African swine fever: how can global spread be prevented?
cord-261634-vfe1lawlIs your phone bugged?
cord-034467-jh9msz1c( PCEP) is a potent enhancer of mixed Th1/ Th2 immune responses in mice immunized with influenza virus antigens Restriction factors: from intrinsic viral restriction to shaping cellular immunity against HIV-1 Expression profiles of the immune genes CD4, CD8β, IFNγ, IL-4, IL-6 and IL-10 in mitogen- stimulated koala lymphocytes( Phascolarctos cinereus) by qRT- PCR Imbalance in the game of T cells: what can the CD4/ CD8 T- cell ratio tell us about HIV and health?
cord-000988-79fp75u3A communitybased outbreak of severe respiratory illness caused by human adenovirus serotype 14 Severe pneumonia due to adenovirus serotype 14: a new respiratory threat?
cord-003855-so8xl199Viruses in bats and potential spillover to animals and humans Bats and viruses: friend or foe?
cord-048229-ajlctjebpath clearer, pathogen killer, or just pathologic?
cord-000990-ci6db90d-A review of epidemiological and diagnostic aspects, with emphasis on type 2c Prevalence and genetic characterization of canine parvoviruses in Korea New approaches for the molecular characterization of canine parvovirus type 2 strains Rapid antigenic- type replacement and DNA sequence evolution of canine parvovirus Natural variation of canine parvovirus Canine and feline parvoviruses can use human or feline transferrin receptors to bind, enter, and infect cells Evolution of canine parvovirus: loss and gain of the feline host Immunogenicity of an intranasally administered modified live canine parvovirus type 2b vaccine in pups with maternally derived antibodies Chronological analysis of canine parvovirus type 2 isolates in Japan Evolution of canine parvovirus- a need for new vaccines?
cord-048368-wm4c7rk6Until 2005 avian influenza was regional problem of sev-[ 4] and question"why had only some wild waterfowl died?"is still unclear.
cord-268560-pwps783yHow might Gadd34 be important for EBNA3C transcriptional activity?
cord-271130-6s79q1c1( Panthera leo) Role of feline immunodeficiency virus in lymphomagenesis-going alone or colluding?
cord-262904-0b0ljjq1Learn more biomedcentral.com/submissions Ready to submit your research Ready to submit your research?
cord-278324-eqqvwwh6Herpes virus fusion and entry: a story with many characters Avian infectious bronchitis virus Viral respiratory diseases( ILT, aMPV infections, IB): are they ever under control?
cord-283689-dzin12qbThe crosstalk between autophagy and apoptosis: where does this lead?
cord-289081-9v04gzhfThen, why is there about the same incidence of RV found in respiratory infections with different degrees of severity?
cord-307364-j86t65quNidovirus transcription: how to make sense …?
cord-284608-ba7wq52tAn association of HPV 16 with squamous cell carcinoma of Waldeyer's tonsillar ring Incidence of human papillomavirus( HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral- induced carcinoma?
cord-295207-0p6x4lwxAre fusion peptides really"sided"insertional helices?
cord-295207-0p6x4lwxCould an infectious trigger explain the differential maternal response to shared placental pathology of preeclampsia and normotensive intrauterine growth restriction?
cord-304058-i8cywew0The large 386-nt deletion in SARS- associated coronavirus: evidence for quasispecies?
cord-304058-i8cywew0what can they teach us about the severe acute respiratory syndrome?
cord-274375-a11ztdpgFurthermore, how does it form kinds of trends in codon usage variation among different stains( Shown in Figure 1) in the condition of the similar nucleotide contents( Table 2)?
cord-274375-a11ztdpgSince HAV mutation rate is much lower than other members of the family Picornaviridae, how does it form such a higher codon usage bias than other members of the family?
cord-274375-a11ztdpgcluster analysis clearly differentiates highly and lowly expressed genes What drives codon choices in human genes?
cord-290976-dhwlr2uiFor example, might the RPTEC be contaminated with a significant pathogen best suited for work in biosafety level-3 or −4 laboratories?
cord-290976-dhwlr2uiWhat is wrong?
cord-302170-k2apj469( DOC 303 kb) Biology and epidemiology of rice viruses On the relationship between rice stripe disease and Delphacodes striatella Fallen Rice black- streaked dwarf virus: its properties, morphology and intracellular localization Biology and molecular biology of viruses in the genus Tenuivirus Infection and symptom in rice stripe disease with special reference to disease- specific protein other than virus Studies on insect transmission of rice virus diseases in Japan Transmission of dwarf, yellow dwarf, stripe and blackstreaked dwarf Research on the inheritance and breeding of rice stripe resistance Identification of rice black- streaked dwarf fijivirus in maize with rough dwarf disease in China Detection and assignment of proteins encoded by rice black streaked dwarf fijivirus S7, S8, S9 and S10 Occurrence of rice black- streaked dwarf disease in late season hybrid rice and its control strategy Real- time PCR: what relevance to plant studies?
cord-302170-k2apj469Quantitative real- time RT- PCR- a perspective Identification of reference genes for RT- qPCR expression analysis in Arabidopsis and tomato seeds Pitfalls of quantitative real- time reverse- transcription polymerase chain reaction Real- time RT- PCR normalisation; strategies and considerations Relative transcript quantification by quantitative PCR: roughly right or precisely wrong?
cord-320693-de1lmzl1: do they have a future as therapeutics?
cord-323009-frej2qmbWhat are the implications for childhood pneumonia of successfully introducing Hib and pneumococcal vaccines in developing countries Childhood pneumonia- progress and challenges Epidemiological and clinical study of viral respiratory tract infections in children from Italy Occurrence of respiratory virus: time, place and person Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology Influenza in Africa Epidemiological and virological influenza survey in Dakar Pandemic A(H1N1)2009 influenza virus detection by real time RT- PCR: is viral quantification useful?
cord-300837-d0a8y5qhephrin- B2 A neutralization test for specific detection of Nipah virus antibodies using pseudotyped vesicular stomatitis virus expressing green fluorescent protein Retrovirus vectors: toward the plentivirus?
cord-300837-d0a8y5qhparamyxovirus F Enveloped viruses: a common mode of membrane fusion?
cord-258935-tatae3hsCharacterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans?
cord-258935-tatae3hsOf virus and bird ecology Human infection with influenza H9N2 Discovery of men infected by avian influenza A( H9N2) virus Cocirculation of avian H9N2 and contemporary"human"H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment?
cord-258935-tatae3hsb Isolation and characterization of prevalent strains of avian influenza viruses in China Molecular characterization of H9N2 influenza viruses: were they the donors of the"internal"genes of H5N1 viruses in Hong Kong?
cord-308397-kqftn75tThe iron metabolism of neoplastic cells: alterations that facilitate proliferation?
cord-339744-xrit0w5iAvian- to- human transmission of H9N2 subtype influenza a viruses: relationship between H9N2 and H5N1 human isolates Cocirculation of avian H9N2 and contemporary"human"H3N2 influenza a viruses in pigs in southeastern China: potential for genetic reassortment?
cord-336870-nirg3269The SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-322738-nvyknvc7Viral pneumonia Rhinoviruses: markers of, or causative for, recurrent wheeze and asthma?
cord-329520-dt0jku7vWhat was the diagnosis of the febrile illness, based on the information provided by the gospels of Mark, Matthew and Luke[ 1]?
cord-329680-ekxsv91t100 years on, are we prepared against the next influenza pandemic?
cord-292794-okh6i4l1Five micrometer sections were cut and stained with hematoxylin and eosin( H&E), and reviewed for histopathologic changes. 2006BAD06A04/03), and the Chinese Research Fund for Non- profit Research Institutions Dual infections of feeder pigs with porcine reproductive and respiratory syndrome virus followed by porcine respiratory coronavirus or swine influenza virus: a clinical and virological study Molecular basis for the generation in pigs of influenza A viruses with pandemic potential Emergence and pandemic potential of swine- origin H1N1 influenza virus Emergence of a novel swine- origin influenza A( H1N1) virus in humans Immunization of pigs with a particle- mediated DNA vaccine to influenza A virus protects against challenge with homologous virus Isolation and genetic analysis of human origin H1N1 and H3N2 influenza viruses from pigs in China Emergence of avian H1N1 influenza viruses in pigs in China Cocirculation of avian H9N2 and contemporary"human"H3N2 influenza A viruses in pigs in southeastern China: potential for genetic reassortment?
cord-347319-lcuma3ehChloroquine is a potent inhibitor of SARS coronavirus infection and spread Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-284630-l9ghggu7Case report Prevalence of canine parvovirus infection in Assam Occurrence of canine parvovirus in dogs from Henan province of China in 2009- 2014 Dog ecology and demography information to support the planning of rabies control in Machakos District Epidemiological study of canine parvovirus Epizootiological status of canine viral haemorrhagic gastroenteritis in Bhubaneswar city Epidemiology of parvovirus and coronavirus infections in dogs in Assam Evolution of canine parvovirus- A need for new vaccines?
cord-284630-l9ghggu7Do two current canine parvovirus type 2 and 2b vaccines provide protection against the new type 2c variant?
cord-284630-l9ghggu7vaccines able to elicit protection against CPV2c subtype in puppies?
cord-325172-a8ntxnmm-how worried should we be?
cord-325172-a8ntxnmma mechanism for the unusual severity of human disease?
cord-318686-we6pveusA comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
cord-318686-we6pveusBat airway epithelial cells: a novel tool for the study of zoonotic viruses More novel hantaviruses and diversifying reservoir hosts- time for development of reservoir- derived cell culture models?
cord-348876-v55piprxEmerg Infect Dis Antigenic and genetic characteristics of H5N1 viruses and candidate vaccine viruses developed for potential use in humanvaccines DNA vaccines: ready for prime time?
cord-300434-obvm2en0Genetic variability among complete human respiratory syncytial virus subgroup a genomes: bridging molecular evolutionary dynamics and epidemiology Positive selection results in frequent reversible amino acid replacements in the G protein gene of human respiratory syncytial virus Genetic variability and molecular evolution of the human respiratory syncytial virus subgroup B attachment G protein Molecular epidemiology of the SH( small hydrophobic) gene of human respiratory syncytial virus( HRSV), over 2 consecutive years Conservation of the respiratory syncytial virus SH gene Inhibition of the human respiratory syncytial virus small hydrophobic protein and structural variations in a bicelle environment Structure and functional dynamics characterization of the ion channel of the human respiratory syncytial virus( hRSV) small hydrophobic protein( SH) transmembrane domain by combining molecular dynamics with excited normal modes Protein- protein interactions of Viroporins in coronaviruses and paramyxoviruses: new targets for antivirals?
cord-300434-obvm2en0since their detection Conservation of G- protein epitopes in respiratory syncytial virus( group a) despite broad genetic diversity: is antibody selection involved in virus evolution?
cord-347569-9fvbshz2A review on current status of antiviral siRNA Combinatorial RNAi: a winning strategy for the race against evolving targets?
cord-342157-qjyooq68Internaltional notes dengue type 3 infection-Nicaragua and Panama Cities spawn epidemic dengue viruses Disease exacerbation caused by sequential dengue infections: myth or reality?
cord-342157-qjyooq68This raises an important question: Is the introduction of different DENV genotypes in disparate geographical locations a result of sequence differences outside of the E gene altering their epidemic potential, or it is simply a stochastic event in viral evolution?
cord-355906-yeaw9nr8Case series from a tertiary care hospital in Sri Lanka Breast milk as a possible route of vertical transmission of dengue virus?
cord-343893-sophqqneFamily Coronaviridae Wet markets-- a continuing source of severe acute respiratory syndrome and influenza?
cord-343893-sophqqneHow do we explain the discrepancy between these data and previous studies that show that fAPN is the receptor for IBV_Ark99 entry?
cord-336510-qzm9wgdeNF- kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells Complex formation of the interferon( IFN) consensus sequence- binding protein with IRF-1 is essential for murine macrophage IFN- gamma- induced iNOS gene expression Does nitric oxide play a critical role in viral infections?
cord-336510-qzm9wgdeNO or no NO?
cord-336510-qzm9wgdeThe acquisition of herpes simplex virus during pregnancy Neonatal herpes simplex virus infection in relation to asymptomatic maternal infection at the time of labor Herpes simplex virus infections of women and their offspring: implications for a developed society Neonatal herpes simplex virus infections: is there a role for immunoglobulin in disease prevention and therapy?
cord-336510-qzm9wgdeinterferon- beta mRNA levels in human fibroblasts Is Wiskott- Aldrich syndrome a cell trafficking disorder?
cord-349287-mwj2qby4: can we go from bench to bedside?
cord-349287-mwj2qby4Nucleocapsid Antibody, Mouse MAb Is MERS another SARS?
cord-349287-mwj2qby4Researchers sought to determine a direction for infection; were DCs transmitting virus to humans or were humans infecting DCs?
cord-349287-mwj2qby4South Korea's MERS response questioned Intensified public health measures help control MERS- CoV outbreak in the Republic of Korea South Korean MERS outbreak spotlights lack of research Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus Isolated in South Korea Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus( MERS- CoV) from the First Imported MERS- CoV Case in China Urgent Call for Research on Middle East Respiratory Syndrome( MERS) in Korea Middle East respiratory syndrome( MERS) in Asia: lessons gleaned from the South Korean outbreak No Respite for Korean Economy Even as MERS Patients Recover Middle East respiratory syndrome coronavirus( MERS- CoV)-China MERS in South Korea and China: a potential outbreak threat?
cord-349287-mwj2qby4The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus Viability of Pseudomonas aeruginosa in cough aerosols generated by persons with cystic fibrosis Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution Middle East respiratory syndrome coronavirus: epidemic potential or a storm in a teacup?
cord-349287-mwj2qby4WHO Statement MERS- CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia Evidence for camel- to- human transmission of MERS coronavirus Taking stock of the first 133 MERS coronavirus cases globally- Is the epidemic changing?
cord-349287-mwj2qby4Why the panic?
cord-318853-mxyxwkhx5 5'UTR geq/ ml at 16 weeks be visible immunologically, but envelope proteins derived from EeRNA sequences corresponding to~10 6- 7 5'UTR geq/ ml at 4- 6 weeks remain unseen?
cord-318853-mxyxwkhxAnalysis of cloned DNA gives cleaner data than PCR sequencing but if 100 clones( and multiple HCV quasispecies clones are highly unlikely to be identical) provides definitive sequence, would we process the 101 st to reveal different and, potentially, critical sequence variations?
cord-318853-mxyxwkhxAnd if we did, how would we recognise its importance?
cord-318853-mxyxwkhxAs clear evidence exists for viral disruption of leptin function[ 106] and virus- associated weight gain in humans[ 107] and monkeys[ 108], is it possible the global epidemics of type II diabetes mellitus, insulin resistance, hyperlipidaemia and obesity now prevalent[ 109][ 110][ 111][ 112][ 113][ 114][ 115][ 116], are just that; epidemics fundamentally caused by viruses that co- opt insulin or leptin or other associated receptors for cell access and generate protein quasispecies that disrupt receptor function?
cord-318853-mxyxwkhxBut does this certitude reflect reality, at least for viral RNA quasispecies?
cord-318853-mxyxwkhxBut why should specific EeRNA sequence frequencies-in other words, HCV RNA pol fidelity-increase after week 8, facilitating adaptive immune responses?
cord-318853-mxyxwkhxCould it also be that ethnically based epidemics of obesity, diabetes mellitus, hypertension and reno- vascular disease( the'metabolic syndrome'), as seen in PIMA Indians, Nauruans and Australian Aborigines[ 115] have developed not primarily because of exposure to"Western"foods and lifestyles-that, after all, are all- pervasive without necessarily having so dramatic an effect on other groups-but because of chronic or recurrent exposure to viruses, or genotypes of viruses to which their particular repertoire of receptor polymorphisms confer no protection?
cord-318853-mxyxwkhxFinally, if immune mechanisms are unable to clear RNA viruses like HCV and do not cause the reduced viral replication seen during acute infection, are they any more likely to be effective against other RNA viruses?
cord-318853-mxyxwkhxI receptor signaling system in JC virus T antigen- induced primitive neuroectodermal tumors-medulloblastomas Hepatitis C virus down- regulates insulin receptor substrates 1 and 2 through up- regulation of suppressor of cytokine signaling 3 Vaccinia virus and the EGF receptor: a portal for infectivity?
cord-318853-mxyxwkhxIs important sequence likely to be present at frequencies of http://www.virologyj.com/content/2/1/70< 1%?
cord-318853-mxyxwkhxIs it possible foetal tolerance is mediated by regulating the fidelity of foetal DNA dependent RNA transcriptases to ensure any cell- surface antigens are expressed heterogeneously and at levels below the threshold of maternal immune responsiveness?
cord-318853-mxyxwkhxIs it possible that self- limiting infections like influenza and SARS also autoregulate their replication, and, like HCV or HBV, become partially dormant, yet remain transcriptionally active, in the face of an active and powerful immune response?
cord-318853-mxyxwkhxThe expected consequences disruption of receptor function by variant viral proteins might explain many common biochemical pathologies; For example, what effect would chronic blockade of parathyroid( PTH) receptors by viral proteins have on PTH levels, the parathyroid glands, or bone?
cord-318853-mxyxwkhxThis is certainly an accurate synthesis of an extensive and highly complex literature but does it make any sense?
cord-318853-mxyxwkhxWhat practical meaning does"immune control"have for the individual?
cord-318853-mxyxwkhxWhy should HCV replicating at 10 6- 7 geq/ ml at week 6 be invisible to the immune system but visible when replicating at 10 5 geq/ ml long term?