trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
of the viral	463
as well as	447
the presence of	373
the use of	312
hepatitis c virus	295
of the virus	289
the development of	282
herpes simplex virus	280
the role of	251
in patients with	239
human immunodeficiency virus	226
influenza a virus	215
one of the	213
in order to	206
severe acute respiratory	191
due to the	183
in addition to	182
the number of	178
a number of	177
it has been	176
the host cell	174
acute respiratory syndrome	171
the viral genome	169
the treatment of	165
been shown to	165
respiratory syncytial virus	159
of viral rna	156
of the host	151
the formation of	149
hepatitis b virus	147
based on the	143
such as the	142
the production of	138
the absence of	138
the case of	136
vesicular stomatitis virus	132
the plasma membrane	130
of patients with	128
a variety of	127
in the case	126
the expression of	126
has also been	123
involved in the	123
of influenza virus	121
immunodeficiency virus type	119
respiratory syndrome coronavirus	118
in the presence	117
in this study	114
the detection of	111
the immune system	110
can be used	110
analysis of the	108
the most common	108
of viral proteins	107
in the viral	107
the importance of	106
of rna viruses	106
is associated with	106
in the absence	106
for the treatment	104
of influenza a	104
the effect of	104
has been shown	103
the viral rna	103
the majority of	102
as a result	102
is required for	101
of viral infections	101
on the other	101
associated with the	100
found to be	100
in cell culture	100
bovine viral diarrhea	99
in the cytoplasm	99
viral replication and	99
structure of the	98
polymerase chain reaction	97
there is a	97
in vitro and	97
the replication of	96
the other hand	95
part of the	93
the fact that	93
viral gene expression	93
role in the	91
the ability to	91
of hepatitis c	90
the pathogenesis of	90
viral diarrhea virus	89
the identification of	89
and in vivo	88
lower respiratory tract	88
simplex virus type	87
innate immune response	87
most of the	87
the ability of	86
end of the	86
some of the	85
the united states	85
type i interferon	85
dependent rna polymerase	85
shown to be	85
of viral infection	84
to be a	84
be used to	84
of herpes simplex	83
of human immunodeficiency	83
the level of	83
members of the	82
expression of the	82
the impact of	82
vitro and in	81
west nile virus	81
the mechanism of	81
the virus to	81
the immune response	80
of viral replication	80
the innate immune	80
has been reported	80
viral load in	79
the study of	79
influenza virus infection	79
a and b	78
of the cell	78
the risk of	78
a result of	77
was found to	77
in the host	77
according to the	76
the discovery of	75
to determine the	74
in response to	74
large number of	74
understanding of the	74
of a virus	72
components of the	72
viruses such as	72
in the united	72
are able to	72
changes in the	71
have been shown	71
the surface of	70
have also been	70
cd t cells	70
has not been	69
of the disease	69
the viral load	69
a total of	69
the generation of	69
a role in	69
and characterization of	68
is able to	68
in terms of	68
in contrast to	68
of respiratory viruses	68
the cell surface	68
of a novel	67
mouth disease virus	67
can also be	67
was shown to	67
in infected cells	67
the context of	67
have been used	67
have been reported	67
the need for	66
it is not	66
were found to	66
viral life cycle	65
to the viral	65
respiratory tract infections	65
the effects of	65
virus infection in	64
have shown that	64
are associated with	64
of viruses in	64
depending on the	64
present in the	64
of the immune	63
was used to	63
of the rna	63
for the detection	63
for the development	63
in children with	63
an important role	62
the synthesis of	62
is essential for	62
of a viral	62
of the most	62
that can be	62
there is no	62
upper respiratory tract	62
h n virus	61
the function of	61
have been identified	61
in which the	61
was associated with	61
in some cases	61
the course of	61
the common cold	61
the release of	61
immune response to	61
activation of the	60
of the human	60
responsible for the	60
important role in	60
a large number	60
in the context	60
the lack of	60
cells infected with	59
well as the	59
associated with a	59
our understanding of	59
the respiratory tract	59
of these viruses	59
the activity of	59
be associated with	58
to be the	58
are involved in	58
an increase in	57
of vesicular stomatitis	57
strand rna viruses	57
function of the	57
the emergence of	57
in our study	57
appears to be	57
internal ribosome entry	57
likely to be	57
the host immune	57
is responsible for	57
the rate of	56
the viral life	56
need to be	56
pandemic h n	56
used for the	56
central nervous system	56
derived from the	55
because of the	55
swine fever virus	55
of type i	55
have not been	55
in the nucleus	55
used as a	55
to the host	55
morbidity and mortality	55
the severity of	55
to viral infection	55
the control of	54
the influenza virus	54
viral infection in	54
found in the	54
the time of	54
contribute to the	54
viral and cellular	54
the inhibition of	54
as a consequence	54
nature of the	54
related to the	54
the process of	54
region of the	53
identification of a	53
h n influenza	53
virus in the	53
middle east respiratory	53
their ability to	52
replication of the	52
the end of	52
world health organization	52
of the same	52
of viral particles	52
in mammalian cells	52
host immune response	52
in the treatment	52
of viral genomes	52
for viral replication	52
east respiratory syndrome	52
of the patients	51
defective interfering particles	51
the diagnosis of	51
the activation of	51
referred to as	51
the induction of	51
on the surface	51
of severe acute	50
in this review	50
binds to the	50
the design of	50
it is important	50
the nature of	50
is one of	50
viral infection and	50
characterization of the	50
may not be	50
and it is	50
mhc class i	49
to the virus	49
binding to the	49
a h n	49
role of the	49
is involved in	49
onset of symptoms	49
activity of the	49
the introduction of	49
to interact with	49
years of age	48
the incidence of	48
the frequency of	48
and in the	48
is based on	48
hepatitis a virus	48
viral nucleic acid	48
of hepatitis b	48
respiratory tract infection	48
been used to	48
wide range of	47
a recent study	47
compared to the	47
are known to	47
a role for	47
it may be	47
of the influenza	47
of the genome	47
been associated with	47
of bovine viral	47
of the hiv	46
the spread of	46
the possibility of	46
viruses have evolved	46
is important to	46
a combination of	46
the amount of	45
the site of	45
more likely to	45
a wide range	45
regions of the	45
from patients with	45
at the time	45
viruses in the	44
addition to the	44
presence of the	44
into the host	44
been reported in	44
respiratory viral infections	44
it is also	44
replication in the	44
mechanism of action	44
r interaction sites	44
in the development	44
presence of a	44
has been demonstrated	44
intensive care unit	44
gene expression and	44
by the viral	44
studies have shown	43
the structure of	43
a range of	43
viruses have been	43
have been developed	43
were used to	43
is mediated by	43
the regulation of	43
the basis of	43
be due to	43
a consequence of	43
were able to	43
one or more	43
and the viral	43
inhibition of the	43
is dependent on	43
the onset of	43
antiviral activity of	43
interfere with the	43
respiratory viruses in	43
showed that the	43
the viral envelope	43
is the most	43
a series of	42
of the infection	42
cells in the	42
remains to be	42
r interaction site	42
in the same	42
immune responses to	42
high levels of	42
insights into the	42
the result of	42
at least one	42
each of the	41
of silver nanoparticles	41
increase in the	41
viral load and	41
surface of the	41
of infected cells	41
be used for	41
the interaction between	41
of the cellular	41
been reported to	41
interact with the	41
the binding of	41
characterization of a	41
infection of the	41
translation of viral	41
type i ifn	41
the interaction of	41
viral load was	41
it is possible	41
and can be	41
the viral replication	40
can be found	40
of gene expression	40
granted medrxiv a	40
the preprint in	40
viral replication in	40
preprint in perpetuity	40
the endoplasmic reticulum	40
has been used	40
acts as a	40
medrxiv a license	40
viral and host	40
a license to	40
license to display	40
has granted medrxiv	40
viral infections in	40
infection in the	40
used in the	40
display the preprint	40
detection of viral	40
the host cells	40
that of the	40
results in the	40
to display the	40
required for the	40
who has granted	40
with the host	39
and has been	39
were shown to	39
in association with	39
a virus infection	39
into the cytoplasm	39
entry into the	39
the virus is	39
than that of	39
with respect to	39
which was not	39
the virus in	39
patients with severe	39
many of the	39
by the virus	39
after onset of	39
mice infected with	39
virus replication in	39
crystal structure of	38
been shown that	38
dependent on the	38
in case of	38
of rna virus	38
in viral replication	38
development of a	38
viral proteins and	38
of the first	38
to that of	38
been found to	38
the existence of	38
detected in the	38
viral respiratory infections	38
the evolution of	38
that have been	38
ribosome entry site	38
are required for	38
mutations in the	38
in the cell	38
are responsible for	38
can lead to	38
at the same	37
seems to be	37
some of these	37
the virus and	37
the management of	37
patients with viral	37
children with asthma	37
viral rna and	37
the most important	37
known to be	37
there was no	37
infl uenza a	37
influenza a and	37
a viral infection	37
of the major	37
role in viral	37
by the host	37
similar to the	37
of viral dna	37
is an important	37
be used as	37
formation of the	37
e and e	37
shown that the	37
and mouth disease	37
the field of	37
resulted in a	36
have been described	36
the cell membrane	36
may be a	36
in situ hybridization	36
on the viral	36
after symptom onset	36
to have a	36
was detected in	36
use of the	36
the addition of	36
of viruses and	36
the prevalence of	36
added to the	36
in recent years	35
results in a	35
virus infection and	35
stranded rna viruses	35
essential for the	35
the potential of	35
of the sars	35
are the most	35
number of viruses	35
of the virion	35
of viral diseases	35
the viral polymerase	35
led to the	35
due to its	35
interaction with the	35
needs to be	35
viral rna replication	35
similar to that	35
as a potential	35
dna and rna	35
considered to be	35
was reported to	35
rna polymerase ii	35
yet to be	35
also known as	35
the efficacy of	35
in the future	34
in the pathogenesis	34
response to viral	34
an rna virus	34
detection of respiratory	34
member of the	34
to assess the	34
from infected cells	34
differences in the	34
patients with a	34
serves as a	34
the type of	34
be involved in	34
in the first	34
on the basis	34
of the viruses	34
a decrease in	34
influenza a viruses	34
in the virus	34
giant cell myocarditis	34
required for viral	34
is thought to	34
virus replication and	34
component of the	34
this is a	34
are essential for	34
thought to be	34
the same time	33
in the human	33
to inhibit the	33
infections in the	33
of viral load	33
interactions with the	33
virus and the	33
reported to be	33
the central nervous	33
the assembly of	33
was observed in	33
have evolved to	33
we found that	33
of vaccinia virus	33
in the early	33
of viral respiratory	33
h y mutant	33
leading to the	33
of the two	33
the relationship between	33
viral protein synthesis	33
it can be	33
use of a	33
innate immune system	32
for the production	32
the type i	32
different types of	32
to the cell	32
of nucleic acid	32
of the protein	32
the results of	32
of host cell	32
respiratory infections in	32
of viral and	32
of eif e	32
gene expression by	32
interaction between the	32
may also be	32
disruption of the	32
african swine fever	32
c virus infection	32
linked to the	32
has been proposed	32
are capable of	32
with a high	32
of the c	32
and in vitro	32
are likely to	32
comparison of the	32
a patient with	32
identification of the	32
which is a	32
has been suggested	32
patients infected with	32
during viral infection	32
the analysis of	32
depends on the	32
the form of	32
a review of	32
by rna interference	31
the author funder	31
to the cytoplasm	31
the infected cells	31
caused by the	31
in the elderly	31
is a major	31
viral and bacterial	31
for the viral	31
it was shown	31
there are several	31
of these proteins	31
of human rhinovirus	31
the potential to	31
binding of the	31
in this case	31
not certified by	31
viruses can be	31
the diversity of	31
an overview of	31
chronic hepatitis c	31
in combination with	31
between the viral	31
certified by peer	31
by peer review	31
of the infected	31
study of the	31
aspects of the	31
of acute respiratory	31
of viral genome	31
for patients with	31
interacts with the	31
may lead to	31
patients with covid	31
associated with increased	31
it is a	31
be found in	31
which in turn	31
the association of	31
is the author	31
with the same	31
knowledge of the	31
due to their	31
the mechanisms of	31
as part of	31
viral genomic rna	31
was not certified	31
the viral proteins	31
appear to be	31
viral rna in	31
to understand the	31
in the formation	31
proteins involved in	30
admitted to the	30
as shown in	30
translation of the	30
lead to the	30
is characterized by	30
data suggest that	30
associated with viral	30
of the mrna	30
serve as a	30
of defective interfering	30
semliki forest virus	30
all rights reserved	30
risk factors for	30
of the innate	30
direct rna sequencing	30
the outcome of	30
the extent of	30
due to a	30
the genome of	30
of the capsid	30
the upper respiratory	30
lymphocytic choriomeningitis virus	30
of action of	30
a mouse model	30
play an important	30
the occurrence of	30
in the past	30
of the antiviral	30
the viral protein	30
with regard to	30
interaction site mutants	30
involved in viral	30
not yet been	30
in a single	30
innate immune responses	30
tumor necrosis factor	30
foot and mouth	30
no reuse allowed	29
of a new	29
the concentration of	29
of h n	29
the h y	29
in the study	29
with the viral	29
degradation of the	29
bind to the	29
two or more	29
the application of	29
in host cells	29
in animal models	29
that may be	29
for detection of	29
in the field	29
should be considered	29
reuse allowed without	29
proteins that are	29
patients with acute	29
innate and adaptive	29
was added to	29
viruses that are	29
prevention and control	29
infections of the	29
the establishment of	29
human and animal	29
that has been	29
also been reported	29
evidence for a	29
included in the	29
for influenza virus	29
composition of the	29
the proportion of	29
the same virus	29
play a role	29
of which are	29
has led to	29
amino acid substitutions	29
suggest that the	29
with and without	29
dna or rna	29
in the respiratory	29
the viral capsid	29
the entry of	29
allowed without permission	29
be able to	29
cleavage of the	29
viral entry into	28
it was found	28
in vivo and	28
total number of	28
classical swine fever	28
the probability of	28
leads to the	28
viral nucleic acids	28
acute respiratory infections	28
the genomic rna	28
is due to	28
small interfering rna	28
of viral pathogens	28
of dengue virus	28
the hepatitis c	28
of ebola virus	28
found that the	28
the infected cell	28
high viral load	28
of viral mrna	28
in the form	28
influenza a h	28
the viral infection	28
of infectious diseases	28
in the last	28
the availability of	28
eif f complex	28
patients with myocarditis	28
of the respiratory	28
more than one	28
that the virus	28
the action of	28
depend on the	28
to interfere with	28
is the case	28
the cell cycle	28
to the same	27
tobacco mosaic virus	27
with influenza a	27
for virus replication	27
contrast to the	27
protein and the	27
it is likely	27
viruses and their	27
in the s	27
gene expression in	27
based on their	27
viral infections of	27
is composed of	27
rna viruses have	27
in most cases	27
rna and dna	27
the distribution of	27
is likely to	27
of a single	27
viruses and the	27
and the host	27
mechanism by which	27
number of viral	27
has been found	27
of children with	27
which may be	27
supported by the	27
and development of	27
can result in	27
of viral pneumonia	27
with or without	27
rate of viral	27
to form a	27
the eif f	27
the in vitro	27
in influenza virus	27
the viral particles	27
be responsible for	27
been used for	27
to the development	27
sequence of the	27
seem to be	27
were detected in	27
diagnosis of viral	27
at the level	27
is important for	27
is related to	27
replication in vitro	26
the age of	26
was shown that	26
holder for this	26
of the common	26
which can be	26
the nucleus and	26
balb c mice	26
between the two	26
a reduction in	26
is a common	26
can be detected	26
to increase the	26
the total number	26
in young children	26
was supported by	26
influenza virus and	26
not required for	26
the accumulation of	26
was found that	26
properties of the	26
the levels of	26
and control of	26
the fi rst	26
production of viral	26
adaptive immune responses	26
structure and function	26
case of the	26
the severe acute	26
clinical characteristics of	26
the copyright holder	26
viral rna synthesis	26
of infectious virus	26
copyright holder for	26
and release of	26
for this preprint	26
the authors declare	26
the recognition of	26
a set of	26
in a study	26
it is now	26
open reading frame	26
has recently been	26
cytotoxic t lymphocytes	26
that the viral	26
the world health	26
the lower respiratory	26
between viruses and	26
and treatment of	26
of the drug	26
the effectiveness of	26
for the virus	26
located in the	26
this is the	26
may contribute to	26
may result in	26
to the presence	25
at the end	25
the prevention of	25
in cultured cells	25
wang et al	25
is required to	25
for the first	25
a key role	25
replicate in the	25
in the brain	25
an immune response	25
suggests that the	25
rna recombination in	25
a group of	25
the possibility that	25
at the cell	25
all of the	25
of animal viruses	25
is similar to	25
rna viruses are	25
viral infection is	25
in the literature	25
respiratory viral infection	25
the viral titer	25
there are two	25
compared with the	25
are needed to	25
only a few	25
of translation initiation	25
was able to	25
production of infectious	25
and function of	25
the combination of	25
in viral pathogenesis	25
in the upper	25
to the plasma	25
from the plasma	25
the duration of	25
each of these	25
into host cells	25
be detected in	25
infection in a	25
in the infected	25
that it is	25
identified in the	25
other respiratory viruses	25
and identification of	25
for disease control	25
the range of	25
been demonstrated to	25
characteristics of the	25
the origin of	25
important for the	25
fusion of the	25
of neutralizing antibodies	25
have to be	24
used to detect	24
are found in	24
analysis of viral	24
several studies have	24
demonstrated that the	24
on the cell	24
respiratory distress syndrome	24
prolonged viral shedding	24
are thought to	24
acute respiratory distress	24
rna viruses in	24
stages of the	24
a systematic review	24
similar to those	24
the antiviral activity	24
is not a	24
are present in	24
to bind to	24
has been associated	24
the most frequently	24
be used in	24
site of the	24
resulting in the	24
hospitalized patients with	24
were found in	24
to study the	24
diseases such as	24
the translation of	24
is likely that	24
this type of	24
on the virus	24
n influenza virus	24
form of the	24
from the cell	24
as in the	24
the golgi complex	24
result in the	24
metagenomic analysis of	24
during the first	24
all of these	24
taxonomy of viruses	24
nuclear export of	24
to reduce the	24
patients in the	24
the percentage of	24
in the laboratory	24
an example of	24
acquired pneumonia in	24
in immunocompromised patients	24
common cause of	24
been implicated in	24
there are many	24
and respiratory syncytial	24
detection of viruses	24
change in the	24
the preparation of	24
ability of the	24
influenza virus replication	24
the nucleic acid	24
to note that	24
inhibition of host	24
been suggested that	24
have been found	24
this work was	24
of the individual	24
observed in the	24
rous sarcoma virus	24
the beginning of	24
of the hepatitis	24
of the membrane	24
nuclear pore complex	24
in a cell	24
in a manner	24
response to the	24
suggested that the	24
respiratory virus infections	23
control of the	23
would like to	23
tract infections in	23
for treatment of	23
the dynamics of	23
in the production	23
together with the	23
of the type	23
inhibition of viral	23
is used to	23
viruses may be	23
infection in vitro	23
of the molecular	23
host and viral	23
proteins of the	23
the complexity of	23
by interacting with	23
remain to be	23
because of their	23
and h n	23
of virus replication	23
mediated by the	23
viral load of	23
viral rna is	23
release of the	23
other rna viruses	23
majority of the	23
effect on the	23
type i ifns	23
consistent with the	23
of this study	23
of viral protein	23
t cell responses	23
in this context	23
in this article	23
at room temperature	23
virus replication by	23
protein in the	23
has been described	23
result in a	23
spread of the	23
plays a role	23
rna viruses and	23
of the eif	23
of respiratory viral	23
the efficiency of	23
its ability to	23
half of the	23
of influenza viruses	23
recent studies have	23
of extracellular vesicles	23
upon infection of	23
the size of	23
viral infections and	23
prior to the	23
cd t cell	23
there was a	23
phase of the	23
in cells infected	23
shown in fig	23
belong to the	23
immune response is	23
the mutant spectrum	23
wide variety of	23
a wide variety	23
in spite of	23
there are no	23
to be determined	23
this suggests that	23
and the presence	23
size of the	23
murine leukemia virus	23
that do not	23
a period of	23
of an rna	23
and replication of	23
is known to	23
li et al	23
of viruses that	23
the first time	23
of viruses to	23
it should be	23
over the past	23
act as a	22
mouse hepatitis virus	22
on the host	22
most common cause	22
of viral nucleic	22
transcription of the	22
review of the	22
the potential for	22
virus infections in	22
from the host	22
eukaryotic initiation factor	22
for the diagnosis	22
the cytoplasm of	22
was used as	22
bovine viral diarrhoea	22
is also a	22
understanding of viral	22
associated with severe	22
centers for disease	22
the most frequent	22
of viral mrnas	22
over the last	22
could be a	22
t cells and	22
also be used	22
and safety of	22
rna interference in	22
of the target	22
in a mouse	22
followed by a	22
also been shown	22
the recruitment of	22
interactions between the	22
is possible that	22
and may be	22
for at least	22
is supported by	22
and expression of	22
post symptom onset	22
of the mutant	22
host immune system	22
encoded by the	22
in the replication	22
obstructive pulmonary disease	22
be related to	22
the vast majority	22
lead to a	22
emerging infectious diseases	22
host protein synthesis	22
yellow fever virus	22
patients with chronic	22
cells of the	22
acute respiratory tract	22
to replicate in	22
at least in	22
revealed that the	22
virus life cycle	22
open reading frames	22
the replication cycle	22
protein of the	22
increased risk of	22
with severe acute	22
which has been	22
to be more	22
of antiviral agents	22
a cause of	22
was the most	22
associated with an	22
released into the	22
that there is	22
international committee on	22
the viral dna	22
in cases of	22
as determined by	22
but not in	22
were associated with	22
the loss of	22
the understanding of	22
mechanisms by which	22
better understanding of	22
of the world	22
to the nucleus	22
of cellular mrnas	22
activated protein kinase	22
molecular mechanisms of	22
immune response in	22
access to the	22
was carried out	22
of mutant spectra	22
rna pol fidelity	22
information on the	22
most of these	22
mutation in the	22
infected cells and	22
chronic obstructive pulmonary	22
to be used	22
a panel of	21
could not be	21
this preprint this	21
to prevent the	21
human host factors	21
of a large	21
such as those	21
h n and	21
mechanisms of viral	21
of coxsackievirus b	21
from a single	21
this version posted	21
in the lung	21
rna virus metagenomics	21
acute otitis media	21
of metal nanoparticles	21
many of these	21
in the course	21
response to infection	21
with the virus	21
only in the	21
focus on the	21
are based on	21
in rna viruses	21
immune response and	21
the hepatitis b	21
cellular immune response	21
small number of	21
domain of the	21
in viral infection	21
the h n	21
in tissue culture	21
respiratory viruses and	21
early stages of	21
viral infections are	21
role of viral	21
of viral shedding	21
synthesis of viral	21
has been observed	21
variation in the	21
and hepatitis c	21
the transmission of	21
is not known	21
viral proteins are	21
recognition of the	21
on the use	21
with acute respiratory	21
as is the	21
and adaptive immune	21
the etiology of	21
was defined as	21
vp and vp	21
during the course	21
preprint this version	21
a prospective study	21
s ribosomal subunit	21
to produce a	21
described in the	21
was performed using	21
for the identification	21
the nuclear pore	21
implicated in the	21
adaptive immune response	21
virus infection of	21
belonging to the	21
it is clear	21
during viral infections	21
the virus from	21
by the presence	21
have been proposed	21
from the same	21
may be the	21
is that the	21
antiviral activity against	21
to elucidate the	21
of other viruses	21
at the plasma	21
of mice with	21
characterized by a	21
to be associated	21
control and prevention	21
are required to	21
was found in	21
to play a	21
of the replication	21
is the only	21
of cd t	21
of the plasma	21
the herpes simplex	21
acute respiratory infection	21
the influence of	20
a matter of	20
molecular biology of	20
in vitro transcription	20
they can be	20
localization of the	20
is necessary to	20
of the family	20
occur in the	20
for the study	20
influenza b virus	20
the university of	20
determination of the	20
of respiratory syncytial	20
into the cell	20
within the host	20
conflict of interest	20
stability of the	20
to determine whether	20
of m a	20
that in the	20
was used for	20
molecular basis of	20
the characteristics of	20
of the population	20
bronchial epithelial cells	20
igm and igg	20
in the regulation	20
correlated with the	20
is determined by	20
a novel coronavirus	20
of myocarditis in	20
b and c	20
isolated from a	20
sequences in the	20
of drug resistance	20
a mutant spectrum	20
cytotoxic t cells	20
proteins such as	20
upstream of the	20
be applied to	20
and it was	20
in a viral	20
released from the	20
to be effective	20
virus in vitro	20
internal ribosomal entry	20
the sensitivity of	20
viruses with a	20
of protein synthesis	20
of the s	20
airway epithelial cells	20
in the next	20
is not required	20
relies on the	20
focused on the	20
high mutation rates	20
infections in children	20
on taxonomy of	20
the degree of	20
and specificity of	20
committee on taxonomy	20
the viral particle	20
determined by the	20
major histocompatibility complex	20
the international committee	20
for rna viruses	20
replication and transcription	20
of host factors	20
there are also	20
the target cell	20
suggesting that the	20
low viral load	20
to be an	20
cellular and viral	20
of novel viruses	20
is not yet	20
latent infection period	20
in rna virus	20
viruses and bacteria	20
the relevance of	20
required for efficient	20
and dna viruses	20
may be associated	20
and the number	20
the adaptive immune	20
such as influenza	20
of dna viruses	20
virus capsid protein	20
work was supported	20
type i and	20
the molecular mechanisms	20
the capsid protein	20
infected with the	20
steps of the	20
there is evidence	19
the amino acid	19
the capacity of	19
and that the	19
the most abundant	19
of the polymerase	19
it is the	19
in children under	19
of cases of	19
in a similar	19
basis for the	19
it has also	19
affected by the	19
when compared to	19
sequence analysis of	19
viral infection of	19
between viral and	19
respiratory tract samples	19
as a cause	19
contributes to the	19
it will be	19
development of the	19
the host response	19
viral safety of	19
may be used	19
vast majority of	19
of the ribosome	19
were collected from	19
in human cells	19
pandemic influenza a	19
bound to the	19
vivo and in	19
this study was	19
small interfering rnas	19
the delivery of	19
portion of the	19
the history of	19
an outbreak of	19
the vaccinia virus	19
disease control and	19
nm in diameter	19
can be made	19
resulted in the	19
acute respiratory illness	19
reduction in the	19
but it is	19
viral particles and	19
factors such as	19
or more of	19
translation and replication	19
been reported that	19
known as the	19
is capable of	19
role of viruses	19
and rna viruses	19
been described in	19
were identified in	19
owing to the	19
capsid protein and	19
are shown in	19
been linked to	19
early stage of	19
evidence that the	19
a lack of	19
of the study	19
of resistance to	19
rna virus infection	19
early and late	19
viruses have developed	19
the degradation of	19
in the control	19
the determination of	19
multiplicity of infection	19
with viral pneumonia	19
high mutation rate	19
treatment of viral	19
to improve the	19
single amino acid	19
a member of	19
is the first	19
the viral and	19
on viral replication	19
of viruses from	19
in humans and	19
virus and host	19
are resistant to	19
that there are	19
eukaryotic translation initiation	19
a virus that	19
structural basis for	19
it does not	19
resistance to the	19
evaluation of the	19
positive and negative	19
severity of the	19
the aim of	19
is caused by	19
treatment of chronic	19
well as to	19
evolution of the	19
by use of	19
is difficult to	19
to be involved	19
economic impact of	19
to evaluate the	19
a viral protein	19
a virus and	19
the selection of	19
of these cells	19
the basis for	19
chen et al	19
role for the	19
isolated from the	19
resulting in a	19
of virus particles	19
proteins in the	19
into the nucleus	19
were treated with	19
viruses in a	19
viral respiratory infection	19
be caused by	19
a study of	19
the gastrointestinal tract	19
in most of	19
state of the	18
from the viral	18
cells in a	18
parts of the	18
a subset of	18
in the process	18
as an example	18
are summarized in	18
a virus to	18
and have been	18
relative abundance of	18
of the newborn	18
shown to have	18
of viral pathogenesis	18
specific th ctl	18
and pathogenesis of	18
isolation and characterization	18
are difficult to	18
of the a	18
are important for	18
s and s	18
the suppression of	18
of a human	18
it appears that	18
in influenza a	18
of novel coronavirus	18
evasion of the	18
plays an important	18
b virus infection	18
to investigate the	18
at risk for	18
and it has	18
sense rna viruses	18
and the virus	18
children and adults	18
as compared to	18
viruses do not	18
the infectivity of	18
were positive for	18
the cost of	18
the genomes of	18
to contribute to	18
to identify the	18
defined as the	18
those of the	18
and b viruses	18
have not yet	18
patients with pneumonia	18
inhibition of hiv	18
rna virus replication	18
the goal of	18
protein that is	18
protein synthesis and	18
of infection in	18
in viral infections	18
the viral genomic	18
of eif g	18
as a model	18
a broad spectrum	18
as the viral	18
of the cases	18
virus is a	18
of antiviral drugs	18
results suggest that	18
mouse model of	18
large amounts of	18
immune responses in	18
out of the	18
in relation to	18
into the cells	18
of the manuscript	18
discovery of the	18
although it is	18
the virus life	18
in some instances	18
interferon regulatory factor	18
of measles virus	18
the success of	18
cell surface receptors	18
the in vivo	18
titer growth rate	18
expression of viral	18
replication and pathogenesis	18
in a wide	18
they have been	18
in clinical trials	18
the present study	18
cell spread of	18
of the genomic	18
can be applied	18
the interaction with	18
is used as	18
of viral entry	18
respiratory disease in	18
and severity of	18
factors involved in	18
of asthma in	18
treatment of covid	18
information about the	18
the disease is	18
the virus can	18
viral diarrhoea virus	18
in the present	18
recent advances in	18
effect of the	18
in complex with	18
there were no	18
detection of human	18
high degree of	18
shi et al	18
as antiviral agents	18
the involvement of	18
viral rna genome	18
presence of viral	18
defective viral genomes	18
as an antiviral	18
of viral disease	18
intercellular adhesion molecule	18
there is an	18
of the total	18
japanese encephalitis virus	18
were the most	18
c virus replication	18
translation initiation factor	18
further studies are	18
proportion of patients	18
and viral load	18
a host cell	18
a source of	18
were more likely	18
identification and characterization	18
a major role	18
of respiratory virus	18
the capsid proteins	18
viral titer growth	18
study of viral	18
interaction of the	18
from the nucleus	18
is possible to	18
the most commonly	18
of the new	18
induced by the	18
is a highly	18
length of stay	18
could also be	18
is critical for	18
virus can be	18
a diagnosis of	18
efficiency of the	18
the viral mrnas	18
has been the	18
well as in	17
which the virus	17
studies suggest that	17
at least two	17
c virus rna	17
structural and functional	17
it is known	17
the concept of	17
of the upper	17
the kinetics of	17
proteins required for	17
along with the	17
is a complex	17
in comparison to	17
limited by the	17
example of a	17
have been detected	17
the human immunodeficiency	17
or in the	17
equine encephalitis virus	17
is present in	17
the cytoplasm and	17
like to thank	17
mutation of the	17
of infection and	17
to the target	17
rna binding proteins	17
of host rna	17
with a single	17
not associated with	17
the target cells	17
replication of viral	17
virus ns protein	17
by the fact	17
ends of the	17
phylogenetic analysis of	17
indicates that the	17
may be due	17
detection of a	17
adaptive immune system	17
in adults with	17
to the immune	17
with viral infection	17
reported that the	17
of a specific	17
to overcome the	17
respiratory tract and	17
large dna viruses	17
with influenza virus	17
for antiviral therapy	17
in vitro studies	17
in hong kong	17
well as a	17
with pandemic h	17
with prolonged viral	17
and viral replication	17
the genetic material	17
the capacity to	17
infection in humans	17
major cause of	17
for the design	17
infection has been	17
to the lack	17
emerged as a	17
immune responses and	17
of innate immune	17
viral genome and	17
of the main	17
by a virus	17
a mixture of	17
a better understanding	17
acute and chronic	17
to infect humans	17
this has been	17
is clear that	17
increased susceptibility to	17
the viral receptor	17
be divided into	17
the cell and	17
been detected in	17
which is the	17
resistant to the	17
critically ill patients	17
the initiation of	17
in viral rna	17
of frog virus	17
a high viral	17
it was also	17
such as hiv	17
the bioaerosol sampler	17
different stages of	17
has been recently	17
studies on the	17
in agreement with	17
the need to	17
of the genus	17
been identified as	17
based on a	17
in one of	17
molecular characterization of	17
an essential role	17
viral respiratory tract	17
in the environment	17
is crucial for	17
translation initiation factors	17
of the role	17
respiratory syndrome virus	17
proven to be	17
of the mechanisms	17
were tested for	17
a function of	17
fold increase in	17
effect on viral	17
corresponding to the	17
regulation of the	17
used to treat	17
part of a	17
were observed in	17
sensitivity and specificity	17
in the community	17
the advent of	17
as a template	17
of the different	17
the s subunit	17
adult patients with	17
of up to	17
shown in figure	17
effects of the	17
there is also	17
is followed by	17
the stability of	17
development of new	17
they do not	17
from the infected	17
host immune responses	17
assembly of the	17
their life cycle	17
infection and the	17
was obtained from	17
in the rna	17
shown in table	17
but also in	17
the epidemiology of	17
entry of the	17
in another study	17
in inhibition of	17
and evolution of	17
of security proteins	17
used to determine	17
viral rna polymerase	17
functions of the	17
step in the	17
positive strand rna	17
for more than	17
of the rnai	17
but also to	17
in virus replication	17
a mechanism of	16
of hiv infection	16
this could be	16
in the range	16
advantage of the	16
viral genome is	16
capsid protein vp	16
that rna viruses	16
seen in the	16
viral replication is	16
gp and gp	16
the acute phase	16
and diversity of	16
the search for	16
of the three	16
has been developed	16
the recovery of	16
previous studies have	16
the patients with	16
viral infections is	16
rift valley fever	16
diversity of the	16
structural proteins of	16
the viral safety	16
authors declare no	16
less likely to	16
in children and	16
of a mutant	16
led to a	16
from herpes simplex	16
of viral meningitis	16
of enveloped viruses	16
infection in patients	16
viral rna genomes	16
for the use	16
neonatal intensive care	16
of human bocavirus	16
to the formation	16
avian influenza virus	16
the viral community	16
cycle viral yield	16
of morbidity and	16
of rna silencing	16
replication and spread	16
plasma for fractionation	16
a receptor for	16
of virus infection	16
a component of	16
and found that	16
can be considered	16
for each of	16
amino acid sequence	16
to have an	16
function in the	16
a viral genome	16
days after onset	16
as previously described	16
in hospitalized patients	16
and by the	16
a viral population	16
for the prevention	16
in hospitalized children	16
is the major	16
incorporated into the	16
our vigen pipeline	16
as described above	16
key role in	16
independent of the	16
against viral infections	16
and in some	16
an in vitro	16
stages of infection	16
genes involved in	16
complexity of the	16
of sendai virus	16
we would like	16
the transfer of	16
targeting the viral	16
leading to a	16
not possible to	16
for drug delivery	16
these proteins are	16
to the cytosol	16
its role in	16
especially in the	16
of pm dm	16
density lipoprotein receptor	16
are presented in	16
regulation of viral	16
is necessary for	16
to block viral	16
not been reported	16
analysis of a	16
the early stages	16
evidence suggests that	16
syncytial virus infection	16
features of the	16
avian influenza a	16
treatment of influenza	16
is consistent with	16
the gut microbiome	16
development of an	16
the structure and	16
children years of	16
zhang et al	16
of infected patients	16
of respiratory tract	16
be detected by	16
n virus infection	16
it is unclear	16
the last decade	16
of the interferon	16
during the last	16
sequences of the	16
example is the	16
human respiratory syncytial	16
supported by a	16
do not have	16
n and h	16
by herpes simplex	16
of rna recombination	16
to be identified	16
it would be	16
but not the	16
used as the	16
among patients with	16
of virus in	16
up to of	16
the last years	16
damage to the	16
and other respiratory	16
in the infection	16
the endosomal membrane	16
and as a	16
infection results in	16
in the diagnosis	16
i interferon induction	16
by a single	16
cellular immune responses	16
high viral loads	16
not detected in	16
by electron microscopy	16
a template for	16
for diagnosis of	16
been demonstrated in	16
of west nile	16
transcription and replication	16
the cleavage of	16
in the design	16
major role in	16
amino acid sequences	16
and of the	16
has been a	16
of these viral	16
are consistent with	16
was not detected	16
to provide a	16
a target for	16
attachment of the	16
ribosomal entry site	16
by a viral	16
were obtained from	16
limited number of	16
expression and replication	16
a cohort of	16
used to identify	16
the method of	16
their role in	16
to evade the	16
found to have	16
acquired immunodeficiency syndrome	16
the causative agent	16
insight into the	16
in a patient	16
strand rna virus	16
e ubiquitin ligase	16
and nucleic acid	16
report of the	16
such as human	16
or absence of	16
some of which	16
venezuelan equine encephalitis	16
early during infection	16
of virus and	16
of host cells	16
expression of a	16
analysis was performed	16
the length of	16
the latent infection	16
exacerbations of asthma	16
impact on the	16
is needed to	15
has to be	15
for up to	15
liu et al	15
to be highly	15
is known that	15
the case for	15
no difference in	15
viral structural proteins	15
viral dna polymerase	15
log copies ml	15
the high mutation	15
and viral rna	15
viral pathogens in	15
the roles of	15
of coronavirus disease	15
there has been	15
of the envelope	15
be present in	15
disease prevention and	15
to the discovery	15
the association between	15
is shown in	15
the abundance of	15
of the proteins	15
brome mosaic virus	15
present on the	15
of eif a	15
group of viruses	15
the hypothesis that	15
as has been	15
to confirm the	15
viral copies ml	15
in respiratory tract	15
lung epithelial cells	15
discovery of new	15
cell lines and	15
pneumonia in adults	15
contributed to the	15
life cycle of	15
for inhibition of	15
this may be	15
the contribution of	15
aid in the	15
were included in	15
in vivo in	15
capacity of the	15
respiratory virus infection	15
to generate a	15
been applied to	15
upper and lower	15
viral load monitoring	15
antiviral innate immune	15
mutation rate of	15
in the genome	15
rna viruses is	15
the removal of	15
viral dna synthesis	15
we did not	15
t cell response	15
virus in a	15
the viral surface	15
which results in	15
rna viruses with	15
the early stage	15
of the ires	15
viral replication cycle	15
the functions of	15
the properties of	15
were used as	15
that could be	15
context of the	15
as a new	15
the fusion protein	15
and activation of	15
specificity of the	15
of cellular proteins	15
of streptococcus pneumoniae	15
that they have	15
the biology of	15
receptor for the	15
such as a	15
identified as a	15
the viral nucleic	15
to the cellular	15
patients with pandemic	15
functions as a	15
in some patients	15
studies of the	15
in infants and	15
viral dna replication	15
were infected with	15
approved by the	15
infection with a	15
to this end	15
against influenza virus	15
infection of cells	15
inhibition of hepatitis	15
to monitor the	15
for development of	15
occurs in the	15
synthesis of the	15
of rna pol	15
solid organ transplant	15
by the same	15
a critical role	15
advances in the	15
other types of	15
could be used	15
for the host	15
as described in	15
potential role of	15
of the dna	15
of chronic hepatitis	15
importance of the	15
the transcription of	15
within the viral	15
the two groups	15
for efficient viral	15
to infect the	15
have been demonstrated	15
be required for	15
factors associated with	15
of viral infectivity	15
the sequence of	15
an antiviral state	15
been demonstrated that	15
these viruses are	15
in a large	15
have been extensively	15
rhinovirus infections in	15
memory t cells	15
of the lung	15
of a particular	15
ribosomal protein l	15
the pathogenicity of	15
with the plasma	15
respiratory viruses are	15
a comparison of	15
be attributed to	15
hayden et al	15
in a host	15
the appearance of	15
no conflict of	15
untranslated region of	15
acute phase of	15
the characterization of	15
low density lipoprotein	15
to block the	15
class i molecules	15
structure of a	15
to form the	15
defective interfering rnas	15
the intensive care	15
of the n	15
the dengue virus	15
in the late	15
it can also	15
side of the	15
a virus in	15
pure viral sepsis	15
the untranslated region	15
between patients with	15
viruses that have	15
and the ability	15
short linear motifs	15
provided by the	15
results indicate that	15
that are not	15
h k me	15
the sars viral	15
antiviral effect of	15
interfering particles of	15
an inhibitor of	15
can be divided	15
be important in	15
in the prevention	15
and inhibition of	15
viral genomes and	15
stages of viral	15
ebola virus disease	15
the chapter by	15
replication in cell	15
the idea that	15
essential for viral	15
another example of	15
avian leukosis virus	15
obtained from the	15
of the anti	15
has been identified	15
this process is	15
infection in mice	15
higher viral load	15
isolation of a	15
as an alternative	15
development of novel	15
and use of	15
a crucial role	15
concentration of the	15
likely to have	15
have the potential	15
initial viral load	15
in the myocardium	15
studies are needed	15
so that the	14
the growth of	14
membrane of the	14
of a host	14
some rna viruses	14
the life cycle	14
viral proteins to	14
for other viruses	14
in the management	14
dynamics of the	14
emergence of new	14
linked immunosorbent assay	14
infected cells is	14
many rna viruses	14
as it is	14
there have been	14
immune response against	14
findings suggest that	14
of human rhinoviruses	14
ill patients with	14
activity in the	14
and west nile	14
the group of	14
of upper respiratory	14
against viral infection	14
proteolytic cleavage of	14
treatment of acute	14
prevalence of viral	14
load in respiratory	14
of in vitro	14
by rna viruses	14
of viral populations	14
able to replicate	14
fact that the	14
enteric viruses in	14
virus from the	14
be an important	14
identification of novel	14
a phase i	14
its interaction with	14
virus that is	14
period of time	14
the interactions between	14
broad spectrum of	14
within the cytoplasm	14
identification of viral	14
the antiviral effect	14
of hepatitis a	14
protein synthesis in	14
viral rna recombination	14
time polymerase chain	14
at least a	14
have demonstrated that	14
inhibition of translation	14
a limited number	14
such that the	14
by binding to	14
in hepatitis c	14
innate immune signaling	14
and influenza virus	14
quasispecies dynamics in	14
viruses that infect	14
been found in	14
the case with	14
to control the	14
entry of viruses	14
rna viruses that	14
diagnosis of respiratory	14
is used for	14
retrospective cohort study	14
in these cases	14
attached to the	14
the isolation of	14
sequencing of the	14
proteasomal degradation of	14
formation of a	14
although there is	14
terminal domain of	14
should not be	14
viral capsid protein	14
in human immunodeficiency	14
steps in the	14
the exception of	14
th ctl memory	14
use of viral	14
a model for	14
in the membrane	14
presence or absence	14
the novel coronavirus	14
is also important	14
does not necessarily	14
viral entry and	14
examination of the	14
in an rna	14
with the development	14
in vitro by	14
of host protein	14
infected with sars	14
in the liver	14
is independent of	14
for in vitro	14
able to inhibit	14
can provide a	14
that contribute to	14
epithelial cells and	14
immune system in	14
was used in	14
plasma membrane of	14
into the viral	14
may be important	14
result of the	14
been identified in	14
absence of a	14
proteins can be	14
large numbers of	14
is linked to	14
sequence of a	14
with the cellular	14
infection of a	14
in the gut	14
for influenza a	14
to those of	14
both of these	14
as a target	14
for replication and	14
a means to	14
a recent report	14
of a number	14
for prevention of	14
has not yet	14
for the synthesis	14
have developed a	14
are characterized by	14
with the replication	14
located at the	14
of this virus	14
a conformational change	14
the specificity of	14
attributed to the	14
are used to	14
systemic lupus erythematosus	14
h n viruses	14
viral genomes are	14
may have been	14
to characterize the	14
assembly and budding	14
of the hcv	14
development of antiviral	14
survival of the	14
to establish a	14
is evidence that	14
has been made	14
able to infect	14
closely related to	14
peak viral load	14
during the early	14
our ability to	14
in line with	14
is cleaved by	14
posterior oropharyngeal saliva	14
and analysis of	14
as a means	14
and detection of	14
of the elderly	14
although there are	14
virus type glycoprotein	14
in this way	14
infectious bronchitis virus	14
high frequency of	14
in adult patients	14
at an early	14
associated with respiratory	14
causative agent of	14
efficacy and safety	14
is incorporated into	14
of this review	14
proof of concept	14
acute viral infections	14
are unable to	14
interacting with the	14
i interferon response	14
the burden of	14
the a brisbane	14
ability to infect	14
can be obtained	14
national center for	14
by influenza virus	14
viral proteins or	14
spread to the	14
important in the	14
to our knowledge	14
in the usa	14
critical role in	14
and is a	14
on the role	14
is defined as	14
protein interacts with	14
tend to be	14
host range and	14
these results suggest	14
the internal ribosome	14
viral genetic material	14
that interact with	14
the manufacture of	14
on the one	14
rna replication and	14
secondary bacterial infections	14
the choice of	14
is well known	14
virus assembly and	14
for viral rna	14
inhibitors of the	14
to the high	14
in clinical samples	14
the one hand	14
by blocking the	14
virion host shutoff	14
been extensively studied	14
are more likely	14
next generation sequencing	14
the observation that	14
in mice infected	14
leading cause of	14
baseline viral load	14
no differences in	14
have been successfully	14
the past years	14
natural history of	14
a broad range	14
children with acute	14
indicate that the	14
types of viruses	14
to describe the	14
overview of the	14
a study by	14
distribution of the	14
studies have been	14
example of the	14
the s ribosomal	14
and to the	14
by viral infection	13
viruses can also	13
the point of	13
production of a	13
infection and is	13
assembly of viral	13
the finding that	13
has shown that	13
the nucleus to	13
the cellular environment	13
it was demonstrated	13
modification of the	13
the emergence and	13
as a novel	13
blood mononuclear cells	13
the pool of	13
safe and effective	13
there are a	13
characterized by the	13
were performed using	13
of the corresponding	13
to produce the	13
the host proteins	13
barrier to resistance	13
in the serum	13
the s protein	13
for production of	13
alterations in the	13
of sequence space	13
the individual c	13
for the presence	13
by small interfering	13
efficient viral replication	13
to enhance the	13
to a new	13
alpha beta interferon	13