quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
sepsis and septic shock	220
in critically ill patients	163
severe sepsis and septic	131
the aim of this	124
of this study was	121
this study was to	118
aim of this study	113
in patients with sepsis	108
patients with severe sepsis	103
the intensive care unit	97
patients with septic shock	91
in patients with severe	80
acute respiratory distress syndrome	73
systemic inflammatory response syndrome	73
in the treatment of	70
has been shown to	69
in the presence of	68
in the pathogenesis of	68
in the intensive care	60
in patients with septic	60
were included in the	56
at the time of	56
of severe sepsis and	54
as well as the	53
admitted to the icu	53
sepsis or septic shock	51
at the end of	51
patients admitted to the	50
a total of patients	49
for the treatment of	48
of this study is	46
the aim of the	46
included in the study	45
critically ill patients with	44
the systemic inflammatory response	41
on the other hand	41
this study is to	40
study was to evaluate	40
of the study was	40
was associated with a	40
of critically ill patients	39
in the absence of	39
is one of the	39
there was no difference	38
between the two groups	38
the study was to	37
of patients with sepsis	37
study was to investigate	37
the end of the	36
mortality in patients with	36
in the control group	35
multiple organ dysfunction syndrome	35
cecal ligation and puncture	35
been shown to be	35
aim of the study	35
management of severe sepsis	35
patients were included in	34
is associated with a	34
was to evaluate the	34
in the development of	34
with severe sepsis and	34
of our study was	33
patients with sepsis and	33
our study was to	33
aim of our study	33
an important role in	33
the area under the	33
have been shown to	32
in intensive care unit	32
to the development of	31
severe sepsis or septic	31
studies have shown that	31
in intensive care units	31
there was no significant	31
the aim of our	31
was significantly higher in	31
in patients with acute	30
as a result of	30
the purpose of this	30
of patients with severe	30
one of the most	29
play a role in	29
a prospective observational study	29
during the study period	29
on the basis of	29
of patients admitted to	28
guidelines for management of	28
was to investigate the	28
in the emergency department	28
of critical care medicine	28
were admitted to the	28
for the use of	27
play an important role	27
icu length of stay	27
duration of mechanical ventilation	27
very low birth weight	27
low birth weight infants	26
in the united states	26
of the inflammatory response	26
of severe sepsis in	26
to the intensive care	26
in the critically ill	26
the treatment of sepsis	25
associated with an increased	25
sequential organ failure assessment	25
for management of severe	25
purpose of this study	24
has been reported to	24
and multiple organ failure	24
peripheral blood mononuclear cells	24
study was to determine	24
higher in patients with	24
at the same time	24
were significantly higher in	23
in the present study	23
definitions for sepsis and	23
study was to assess	23
tumor necrosis factor alpha	23
the host response to	23
in a murine model	23
total of patients were	23
on the day of	23
in the pathophysiology of	23
was found to be	23
divided into two groups	23
in the first h	22
a role in the	22
area under the curve	22
international guidelines for management	22
hospital length of stay	22
in mechanically ventilated patients	22
and is associated with	22
statistical analysis was performed	22
the surviving sepsis campaign	22
length of icu stay	22
the severity of the	22
patients with and without	22
no significant differences between	22
was to assess the	22
can be used to	22
in the context of	22
ventilator dependence risk score	22
study was to compare	21
there were no significant	21
was no difference in	21
the present study was	21
role in the pathogenesis	21
the innate immune system	21
of acute kidney injury	21
in vitro and in	21
length of stay in	20
adult respiratory distress syndrome	20
who were admitted to	20
in this study we	20
at a dose of	20
were no significant differences	20
before and after the	20
there was a significant	20
an independent risk factor	20
of tumor necrosis factor	20
a murine model of	20
innate and adaptive immune	20
apache ii score was	19
these data suggest that	19
analysis was performed using	19
did not differ between	19
the objective of this	19
the presence of a	19
was to determine the	19
in a model of	19
patients with acute respiratory	19
in septic shock patients	19
was no significant difference	19
sepsis and multiple organ	19
outcome in patients with	18
are shown in table	18
sepsis in the united	18
were divided into two	18
of multiple organ failure	18
there were no differences	18
were found to be	18
patients were divided into	18
important role in the	18
the treatment of severe	18
has been associated with	18
associated with increased mortality	18
it has been shown	18
host response to infection	18
had no effect on	18
and septic shock in	18
objective of this study	18
with sepsis and septic	18
is associated with increased	18
in the number of	18
to be associated with	18
admission to the icu	18
for the management of	17
it has been reported	17
of the present study	17
medical intensive care unit	17
the development of sepsis	17
in very low birth	17
within the first h	17
been reported to be	17
with an increased risk	17
in the management of	17
for the development of	17
systemic infl ammatory response	17
during the first days	17
as well as a	17
surgical intensive care unit	17
during the course of	17
significantly higher in the	17
the innate and adaptive	17
was not associated with	17
of sepsis and septic	17
independent risk factor for	17
treatment of severe sepsis	17
and the presence of	16
it was found that	16
of the immune system	16
and chronic health evaluation	16
an intensive care unit	16
aim of the present	16
have been reported to	16
an increased risk of	16
no significant difference in	16
a risk factor for	16
severe sepsis in the	16
little is known about	16
in the setting of	16
a major role in	16
vitro and in vivo	16
with the development of	16
a significant increase in	16
epidemiology of severe sepsis	16
in a rat model	16
study is to evaluate	16
a mouse model of	16
in a mouse model	16
we conducted a prospective	16
these results suggest that	16
has been reported that	16
a wide range of	16
studies are needed to	16
with severe sepsis or	16
in an attempt to	16
a mean age of	15
length of stay and	15
is associated with an	15
admitted to the intensive	15
over a period of	15
in severe sepsis and	15
systematic review and meta	15
the ability of the	15
length of hospital stay	15
our aim was to	15
physiology and chronic health	15
acute physiology and chronic	15
significant differences between the	15
and treatment of sepsis	15
a rat model of	15
for the first time	15
with a mean age	15
of sepsis in the	15
a systematic review and	15
survival in patients with	15
the first h after	15
may contribute to the	15
is involved in the	14
present study was to	14
associated with a higher	14
significant difference between the	14
apache ii and sofa	14
mean arterial blood pressure	14
of reactive oxygen species	14
the role of the	14
the first days of	14
the purpose of the	14
sepsis and organ failure	14
in acute lung injury	14
is to evaluate the	14
objectives of the study	14
the third international consensus	14
were included in this	14
the number of patients	14
of the septic syndromes	14
samples were collected from	14
we performed a retrospective	14
evaluate the effect of	14
the innate immune response	14
tissue factor pathway inhibitor	14
efficacy and safety of	14
and the use of	14
as well as in	14
for sepsis and septic	14
mean apache ii score	14
be involved in the	14
children with septic shock	14
increase the risk for	14
the apache ii score	14
and multiple organ dysfunction	14
in addition to the	14
the adaptive immune system	14
all patients admitted to	14
infl ammatory response syndrome	14
in the course of	14
to evaluate the effect	14
correlation was found between	14
and the number of	14
in patients admitted to	14
the use of a	13
international consensus definitions for	13
there was no correlation	13
in neonates with sepsis	13
under the roc curve	13
during the first hours	13
the pathophysiology of sepsis	13
in a variety of	13
icu and hospital mortality	13
and length of stay	13
the treatment of septic	13
further studies are needed	13
the pathogenesis of sepsis	13
of the coagulation cascade	13
patients with sepsis syndrome	13
of acute lung injury	13
of the adaptive immune	13
was significantly lower in	13
patients were admitted to	13
no significant differences in	13
of the patients were	13
of the complement system	13
were enrolled in the	13
guidelines for the use	13
development of multiple organ	13
blood samples were collected	13
a key role in	13
the expression of cd	13
for critically ill patients	13
the first hours of	13
for more than h	13
was defined as the	13
critically ill patients is	13
society of critical care	13
consensus definitions for sepsis	13
and the incidence of	13
patients at risk of	13
of the immune response	13
cause of death in	13
third international consensus definitions	13
the time course of	13
under the receiver operating	13
area under the roc	13
treatment of septic shock	13
the outcome of patients	13
and the occurrence of	13
did not differ significantly	13
had at least one	13
these reports suggest that	12
simplified acute physiology score	12
inducible nitric oxide synthase	12
the total number of	12
be used as a	12
the first day of	12
with acute respiratory failure	12
play a major role	12
were randomized to receive	12
at the onset of	12
on the surface of	12
of our study is	12
in the icu and	12
stay in the icu	12
a decrease in the	12
to the icu with	12
patients admitted to a	12
area under the receiver	12
levels in patients with	12
in a number of	12
may be related to	12
length of stay was	12
fraction of inspired oxygen	12
an increase in the	12
was no correlation between	12
study was designed to	12
outcome of patients with	12
differences between the groups	12
is thought to be	12
in the first hours	12
the host immune response	12
and tumor necrosis factor	12
in the production of	12
these data indicate that	12
patients with or without	12
a median age of	12
are involved in the	12
severe acute respiratory syndrome	12
the results of the	12
in human septic shock	12
organ failure and death	12
there was no statistical	12
the mean age was	12
of icu stay and	12
a large number of	12
chronic health evaluation ii	12
the severity of sepsis	12
study was conducted in	12
with the severity of	12
a randomized controlled trial	12
the acute respiratory distress	12
associated with high mortality	12
was no difference between	12
most common cause of	12
of the patients with	11
a major cause of	11
be one of the	11
the ventilator dependence risk	11
patients admitted in the	11
a mean arterial pressure	11
the development of the	11
in response to lps	11
treatment of patients with	11
the primary outcome was	11
our study is to	11
intensive care and emergency	11
at the beginning of	11
of patients with a	11
as a marker of	11
complicating acute myocardial infarction	11
the multiple organ dysfunction	11
the course of the	11
human activated protein c	11
in the icu setting	11
by the presence of	11
in patients with sirs	11
of death in the	11
of a number of	11
this is the first	11
this study aimed to	11
to be involved in	11
in patients with multiple	11
in the prowess trial	11
recombinant human activated protein	11
in patients with a	11
in the regulation of	11
of the innate immune	11
associated with a high	11
care and emergency medicine	11
with the use of	11
it is important to	11
the receiver operating characteristic	11
for more than hours	11
during their icu stay	11
the inflammatory response in	11
host response to sepsis	11
and was associated with	11
role in the development	11
for each of the	11
of multiple organ dysfunction	11
of morbidity and mortality	11
of patients with acute	11
was the most common	11
after the onset of	11
were more likely to	11
the expression of mir	11
patients admitted to our	11
safety and efficacy of	11
enrolled in the study	11
with a median age	11
these results indicate that	11
in the first days	11
is known about the	11
with acute respiratory distress	11
acute lung injury and	11
plasminogen activator inhibitor type	11
the most common cause	11
morbidity and mortality in	11
with septic shock and	11
of intensive care unit	11
in the face of	10
at least in part	10
a dose of mg	10
a significant decrease in	10
and guidelines for the	10
during the icu stay	10
was associated with an	10
difference between the two	10
over a month period	10
the use of innovative	10
the first h of	10
in surgical intensive care	10
admitted to our icu	10
of stay in icu	10
with an increase in	10
may be associated with	10
acute kidney injury in	10
evaluate the impact of	10
was to compare the	10
a systemic inflammatory response	10
patienten mit kardiogenem schock	10
activated protein c for	10
of stay in the	10
for severe sepsis and	10
is a common complication	10
end of the experiment	10
in the inflammatory response	10
investigate the effects of	10
coronary artery bypass grafting	10
in icu patients with	10
a pivotal role in	10
a high risk of	10
the expression of the	10
severe traumatic brain injury	10
in a series of	10
in the acute phase	10
significantly higher in patients	10
the detect sepsis sensor	10
may be due to	10
is considered to be	10
was not statistically significant	10
the american college of	10
role in the pathophysiology	10
of innovative therapies in	10
which is associated with	10
blood samples were taken	10
for sepsis and organ	10
between survivors and non	10
mortality in critically ill	10
on the cell surface	10
a better understanding of	10
was significantly higher than	10
in patients treated with	10
with a high mortality	10
data are presented as	10
a retrospective analysis of	10
at the level of	10
appears to be a	10
increase the risk of	10
in critically ill adults	10
in a university hospital	10
patients undergoing cardiac surgery	10
presence or absence of	10
no significant difference between	10
compared to patients with	10
innovative therapies in sepsis	10
for the prevention of	10
with respect to the	10
human umbilical vein endothelial	10
were significantly lower in	10
the development of a	10
weaning from mechanical ventilation	10
patients at risk for	10
the critically ill patients	10
the course of sepsis	10
umbilical vein endothelial cells	10
signs and symptoms of	10
to investigate the effect	10
investigate the effect of	10
use of innovative therapies	10
continuous renal replacement therapy	10
the safety and efficacy	10
the production of il	10
one of the major	10
to play an important	10
failure and guidelines for	9
was defined by the	9
the mean age of	9
the incidence of delirium	9
in intensive care patients	9
a significant reduction in	9
of patients were included	9
therapy in the treatment	9
a prospective cohort study	9
high risk of death	9
after the administration of	9
of the severity of	9
left ventricular ejection fraction	9
it is known that	9
study was approved by	9
median age of years	9
and organ failure and	9
adult patients admitted to	9
observed in patients with	9
a retrospective observational study	9
pg ml in the	9
associated with an increase	9
the diagnosis of sepsis	9
the nature of the	9
to the presence of	9
our understanding of the	9
the sequential organ failure	9
within the first hours	9
with a sensitivity of	9
need for renal replacement	9
major role in the	9
not differ significantly between	9
and the severity of	9
a higher risk of	9
our intensive care unit	9
been found to be	9
was defined as a	9
of the innate and	9
the cause of death	9
the presence or absence	9
in children with septic	9
of the critically ill	9
of the patients in	9
was approved by the	9
the leading cause of	9
prior to icu admission	9
study was carried out	9
on mortality in patients	9
the inflammatory response and	9
patients who were admitted	9
has been shown that	9
cardiogenic shock complicating acute	9
were no differences in	9
the adult respiratory distress	9
in comparison to the	9
the early phase of	9
diagnosis and treatment of	9
was seen in patients	9
in animal models of	9
dependence risk score was	9
was higher in patients	9
no effect on the	9
be due to the	9
those who did not	9
the majority of patients	9
and negative predictive value	9
patients who did not	9
prevention and treatment of	9
regulates the expression of	9
a report from the	9
randomized to receive either	9
was independently associated with	9
or in combination with	9
may be responsible for	9
of patients with septic	9
admitted to the medical	9
risk of death in	9
were not significantly different	9
were admitted to icu	9
a central role in	9
the protective effect of	9
as a consequence of	9
are likely to be	9
the presence of infection	9
with a diagnosis of	9
in any of the	9
the onset of sepsis	9
intensive care unit of	9
dose of mg kg	9
critically ill patients and	9
was used to assess	9
in the plasma of	9
organ failure and guidelines	9
been implicated in the	9
the relationship between the	9
to the severity of	9
a result of the	9
in sepsis and septic	9
the activation of the	9
of mechanical ventilation and	9
the early stages of	9
with acute myocardial infarction	9
total of patients with	9
compared to the control	9
is associated with poor	9
to play a role	9
associated with higher mortality	9
total body surface area	9
used in this study	9
in an intensive care	9
the shock trial registry	9
no statistically significant difference	9
receiver operating characteristic curve	9
could be used as	8
c for severe sepsis	8
between patients with and	8
and associated costs of	8
in a prospective study	8
associated with severe sepsis	8
pathophysiology and treatment of	8
activation of the coagulation	8
was used to identify	8
return of spontaneous circulation	8
should not be used	8
neonatal intensive care unit	8
a member of the	8
in response to a	8
at a rate of	8
a retrospective cohort study	8
we investigated the effects	8
therapy in patients with	8
the predictive value of	8
study was performed in	8
on the presence of	8
patients with sepsis or	8
for the diagnosis of	8
research is needed to	8
we have shown that	8
was obtained from the	8
kg ideal body weight	8
a wide variety of	8
risk factor for dementia	8
patients admitted to icu	8
in preterm infants with	8
this group of patients	8
has been shown in	8
the authors concluded that	8
risk factors associated with	8
death in patients with	8
to the site of	8
has been demonstrated to	8
incidence and mortality of	8
leading cause of death	8
and septic shock patients	8
esicm accp ats sis	8
both groups of patients	8
the patients in the	8
patients with suspected sepsis	8
of the systemic inflammatory	8
was performed using the	8
at high risk of	8
with acute renal failure	8
low birth weight neonates	8
bei patienten mit septischem	8
ii and sofa score	8
with a decrease in	8
a tidal volume of	8
a single dose of	8
associated costs of care	8
multiple organ failure in	8
in contrast to the	8
in the first week	8
protein c for severe	8
innate and adaptive immunity	8
the severity of acute	8
was to describe the	8
was lower in the	8
reduce the risk of	8
the effect of a	8
intensive care unit and	8
an increased risk for	8
activities of daily living	8
chronic obstructive pulmonary disease	8
no difference between the	8
of recombinant human activated	8
in accordance with the	8
one of the main	8
in the use of	8
the pathophysiology and treatment	8
there are a number	8
adult patients with sepsis	8
the level of the	8
been shown to improve	8
to the emergency department	8
may be useful in	8
for more than days	8
the development of multiple	8
the levels of il	8
acute renal failure in	8
to investigate the effects	8
the time of admission	8
was not significantly different	8
from january to december	8
the pathogenesis of the	8
critically ill patients in	8
of nitric oxide synthase	8
associated with a decrease	8
conducted a prospective observational	8
the inflammatory response to	8
model was used to	8
these findings suggest that	8
myocardial infarction complicated by	8
in both groups of	8
intensive care unit patients	8
up to h after	8
within the normal range	8
enrolled in this study	8
be responsible for the	8
of this study were	8
in patients suffering from	8
reduce the incidence of	8
have been associated with	8
by cecal ligation and	8
critically ill patients admitted	8
this study aims to	8
report from the shock	8
significant difference in the	8
are a number of	8
with low doses of	8
patients at high risk	8
is the most common	8
included in this study	8
multiple organ failure and	8
a higher incidence of	8
is a risk factor	8
significantly higher than the	8
the effect of sepsis	8
were divided into groups	8
our results suggest that	8
significantly lower in patients	8
days of mechanical ventilation	8
data are expressed as	8
from the shock trial	8
a number of studies	8
in the form of	8
high levels of il	8
can be found in	8
sepsis is associated with	8
a significant role in	8
with acute lung injury	8
contribute to the development	8
are presented as median	8
increased risk for infection	8
were higher in patients	8
ml kg ideal body	8
the majority of the	8
the length of icu	8
and a specificity of	8
associated with mortality in	8
associated with septic shock	8
by the use of	8
a co c a	8
our data suggest that	8
are expressed as mean	8
admitted in the icu	8
with multiple organ failure	8
the potential role of	8
of the contact system	8
mechanically ventilated patients with	8
severe systemic inflammatory response	8
acute respiratory syndrome coronavirus	8
international sepsis definitions conference	8
patients were followed up	8
in patients with chronic	8
did not show any	8
sepsis in very low	8
higher risk of death	8
sepsis and organ dysfunction	8
to the control group	8
play a key role	8
and to evaluate the	8
patienten mit schwerer sepsis	8
test was used to	8
stress doses of hydrocortisone	8
induced acute lung injury	8
of activated protein c	8
of septic shock patients	8
management of patients with	8
sccm esicm accp ats	8
year after icu admission	8
in human endothelial cells	8
the goal of this	8
the results indicate that	8
lower in patients with	8
complicated by cardiogenic shock	8
college of critical care	7
the management of severe	7
was a significant difference	7
during the period of	7
prospective observational study of	7
the epidemiology of sepsis	7
with acute kidney injury	7
none of the patients	7
of sepsis and multiple	7
american college of critical	7
risk of death and	7
in patients with or	7
has been studied in	7
in the early stage	7
or more of the	7
at the start of	7
patients were randomized to	7
on the one hand	7
and outcome of severe	7
lower than that of	7
with a higher mortality	7
the immune status of	7
that there is a	7
of acute respiratory distress	7
should be considered in	7
patients with respiratory failure	7
the presence of il	7
play a central role	7
age of the patients	7
sepsis is one of	7
septic critically ill patients	7
the impact of the	7
a higher rate of	7
duration of hospital stay	7
respiratory distress syndrome in	7
in neutropenic patients with	7
was calculated as the	7
involved in the development	7
but there was no	7
on admission to the	7
the immune response to	7
the start of the	7
is based on the	7
treatment of neonatal sepsis	7
expressed on myeloid cells	7
least one episode of	7
in the study and	7
it is associated with	7
the source of infection	7
studies suggest that the	7
was measured by the	7
in vivo and in	7
of the patients was	7
tested the hypothesis that	7
white blood cell count	7
for renal replacement therapy	7
volume of ml kg	7
rats were subjected to	7
similar in both groups	7
differences between groups were	7
pediatric intensive care unit	7
was significantly decreased in	7
onset sepsis in very	7
are associated with increased	7
was to determine whether	7
analysis was used to	7
at the moment of	7
surviving sepsis campaign guidelines	7
patients with multiple trauma	7
associated with increased risk	7
the site of infection	7
and in patients with	7
along the sepsis timeline	7
the prevalence of pfo	7
the acute phase response	7
mortality in septic patients	7
associated with ventilator dependence	7
did not meet any	7
the development of acute	7
to the medical icu	7
the absence of a	7
tumor necrosis factor receptor	7
the evaluation of the	7
safety of recombinant human	7
mortality in septic shock	7
it is difficult to	7
prospective observational study was	7
the beginning of the	7
in the near future	7
this study were to	7
assessment method for the	7
are the most common	7
macrophage migration inhibitory factor	7
the importance of the	7
we have studied the	7
and safety of recombinant	7
the aim was to	7
significant differences in the	7
severe sepsis or shock	7
an increased incidence of	7
in critically ill children	7
and central nervous system	7
at later time points	7
apoptotic cell death in	7
no correlation between the	7
the major cause of	7
e a r s	7
recent studies have shown	7
of organ dysfunction in	7
of nitric oxide in	7
confusion assessment method for	7
and acute respiratory distress	7
at least one episode	7
in the patients with	7
septic shock patients with	7
with the presence of	7
survival of patients with	7
incidence of severe sepsis	7
a leading cause of	7
patients with sepsis are	7
used for statistical analysis	7
of patients at risk	7
included in the analysis	7
patients in the icu	7
the critically ill patient	7
of patients in the	7
was associated with higher	7
was used to compare	7
shock complicating acute myocardial	7
has been proposed as	7
of the sofa score	7
to evaluate the impact	7
multiple organ dysfunction score	7
production of reactive oxygen	7
in a decrease in	7
red blood cell transfusion	7
as an indicator of	7
study is to assess	7
bei patienten mit sepsis	7
changes in gene expression	7
and septic shock are	7
investigated the effects of	7
have shown that the	7
determine the impact of	7
inflammatory response syndrome and	7
parameters for hemodynamic support	7
in the early stages	7
can be used as	7
sepsis und septischem schock	7
severe sepsis septic shock	7
of severe sepsis or	7
we aimed to investigate	7
we tested the hypothesis	7
study of patients with	7
were not able to	7
acute myocardial infarction complicated	7
in preterm neonates with	7
associated with increased morbidity	7
been proposed as a	7
were classified according to	7
were enrolled in this	7
we were able to	7
was observed in the	7
intensive care med doi	7
in an experimental model	7
on the first day	7
test was used for	7
patients with multiple organ	7
with systemic inflammatory response	7
h after sepsis induction	7
was seen in the	7
the need for intubation	7
patients with hematologic malignancies	7
outcome of severe sepsis	7
the inhibition of the	7
in the clinical setting	7
extremely low birth weight	7
the prognostic value of	7
involved in the pathogenesis	7
between january and december	7
no difference in the	7
were randomly assigned to	7
the th and th	7
in septic patients and	7
of the patients had	7
in the postoperative period	7
was to analyze the	7
was used to determine	7
the aims of this	7
of the most important	7
may play a role	7
patients with severe ards	7
of intensive care medicine	7
for hemodynamic support of	7
f v t ratio	7
accp ats sis international	7
management of sepsis and	7
two groups of patients	7
in the serum of	7
has been implicated in	7
is associated with decreased	7
with the aim of	7
there is also a	7
child with septic shock	7
seems to be the	7
data were analyzed by	7
our results show that	7
in patients who died	7
significantly lower in the	7
could be used to	7
at the intensive care	7
as compared to the	7
in the placebo group	7
of red blood cells	7
in the first period	7
of septic shock in	7
the plasma levels of	7
has been used in	7
increases the risk for	7
a significant difference between	7
united kingdom critical care	7
y e a r	7
course of the disease	7
in of the patients	7
for the detection of	7
a critical role in	7
for patients with severe	7
study was to describe	7
the presence of an	7
defined by the presence	7
are known to be	7
for acute lung injury	7
effects were observed in	7
review of the literature	7
associated with the development	7
ats sis international sepsis	7
of the patients who	7
practice parameters for hemodynamic	7
levels were measured by	7
to multiple organ failure	7
did not lead to	7
in this group of	7
of acute renal failure	7
morbidity and mortality rates	7
ii and sofa scores	7
in the early phase	7
high morbidity and mortality	7
studied the effect of	7
in the incidence of	7
the main cause of	7
in combination with the	7
for a period of	7
results suggest that the	7
directed therapy in the	7
during the first h	7
differences between the two	7
patients who were ventilated	7
as part of the	7
a review of the	7
in intensive care and	7
in the case of	7
patients with acute pancreatitis	7
of lactic acid bacteria	6
ill patients with acute	6
a high mortality rate	6
further research is needed	6
more likely to have	6
at the expense of	6
were excluded from the	6
and duration of mechanical	6
left cerebral hemisphere tumor	6
the lack of a	6
a period of years	6
in patients who survive	6
been shown to reduce	6
may be involved in	6
and organ dysfunction in	6
as the presence of	6
of the surviving sepsis	6
intensive insulin therapy in	6
the whole study period	6
there has been a	6
and improves survival in	6
in up to of	6
was found in patients	6
study was to examine	6
not an independent risk	6
the management of sepsis	6
patients were classified according	6
discharge from the icu	6
a dysregulated host response	6
vivo and in vitro	6
study were to determine	6
significantly higher than in	6
expression of adhesion molecules	6
that the administration of	6
it is concluded that	6
a positive correlation between	6
the central nervous system	6
might be due to	6
limb or digit threat	6
a significant impact on	6
critically ill septic patients	6
the implementation of the	6
useful in the treatment	6
are presented as mean	6
on intensive care unit	6
in surgical icu patients	6
study was to analyze	6
common cause of death	6
in comparison with the	6
receptor expressed on myeloid	6
cause of mortality in	6
in patients with ards	6
be the result of	6
has not yet been	6
mixed venous oxygen saturation	6
intensive care unit admission	6
in preterm and term	6
in a cohort of	6
shown to be a	6
day of icu admission	6
were significantly correlated with	6
arterial blood pressure and	6
we found statistically highly	6
difference was found between	6
the impact of these	6
patients with critical illness	6
patients in intensive care	6
as a biomarker of	6
has also been shown	6
a logistic regression model	6
is a lack of	6
from april to march	6
this was a prospective	6
have been observed in	6
a reduction in the	6
the routine use of	6
and adaptive immune system	6
related organ failure assessment	6
the increased susceptibility to	6
the outcome of the	6
in a patient with	6
involved in the regulation	6
admitted to intensive care	6
mortality and morbidity in	6
difference between the groups	6
this may be due	6
it should be noted	6
at least two of	6
infectious causes of systemic	6
were not statistically different	6
patients were admitted in	6
found statistically highly significant	6
and the release of	6
the french multicenter study	6
to a decrease in	6
is not associated with	6
not associated with a	6
is responsible for the	6
ventilated for more than	6
associated with poor outcome	6
a systematic review of	6
a median of days	6
to test the hypothesis	6
outcomes in patients with	6
the administration of ivig	6
retrospective study of patients	6
and a time to	6
investigated the effect of	6
the effects of these	6
an animal model of	6
was higher in the	6
compared to healthy controls	6
anesthesiology and intensive care	6
the beneficial effects of	6
is followed by a	6
aims of this study	6
admission to intensive care	6
up to of patients	6
management of odontogenic infections	6
with increased mortality in	6
compared with the control	6
higher than in the	6
with increased risk for	6
associated with improved survival	6
to determine the impact	6
does not appear to	6
as tumor necrosis factor	6
has been suggested that	6
after acute myocardial infarction	6
after the start of	6
related quality of life	6
seems to be a	6
we have investigated the	6
causes of systemic inflammation	6
h and h after	6
patients with systemic inflammatory	6
is an independent risk	6
two groups according to	6
the treatment of patients	6
a significant proportion of	6
we conclude that the	6
purpose of the study	6
in the isoflurane group	6
is to assess the	6
in pediatric septic shock	6
at t and t	6
between survivors and nonsurvivors	6
a higher mortality rate	6
society of intensive care	6
of fresh frozen plasma	6
been shown to inhibit	6
with left cerebral hemisphere	6
have a significant impact	6
in the diagnosis of	6
samples were obtained from	6
high mobility group box	6
to be related to	6
were included in a	6
the effect of the	6
one of the first	6
study of patients admitted	6
expression of cd b	6
a cohort of patients	6
chronic critically ill patients	6
within the first days	6
is well known that	6
risk factor for mortality	6
c bl sccr mice	6
high sensitivity and specificity	6
respiratory and hemodynamic parameters	6
after the initiation of	6
early stages of sepsis	6
it has been suggested	6
organ dysfunction in the	6
better understanding of the	6
diagnosis of severe sepsis	6
have been implicated in	6
was carried out in	6
need for mechanical ventilation	6
the expression of a	6
hospital mortality rate of	6
aimed to determine the	6
turned out to be	6
innerhalb der ersten h	6
was used as a	6
patienten mit septischem schock	6
the activity of the	6
at high risk for	6
is believed to be	6
in the release of	6
were observed in the	6
sis international sepsis definitions	6
the result of a	6
and the acute respiratory	6
in experimental models of	6
in patients with major	6
with the number of	6
associated with hospital mortality	6
the characteristics of the	6
is likely to be	6
epidemiology of sepsis in	6
are associated with an	6
to identify patients with	6
to reduce the risk	6
these results show that	6
the regulation of the	6
the distribution of igm	6
of the most common	6
intensive care unit in	6
the patients who developed	6
increased in both groups	6
serum of patients with	6
and critical care medicine	6
higher than that of	6
to the use of	6
is associated with high	6
of patients who were	6
effect of sepsis on	6
was no statistically significant	6
the expression of il	6
as compared with the	6
patients with severe trauma	6
patients were enrolled in	6
of patients were admitted	6
the two groups were	6
to determine the effect	6
than in the control	6
icu and hospital stay	6
have been used to	6
determine the effect of	6
on the use of	6
a prospective study of	6
with sepsis or septic	6
analysis was performed to	6
were lower in the	6
with acute liver failure	6
to improve the outcome	6
primary outcome measure was	6
has been found to	6
the study was approved	6
there is a lack	6
days of icu stay	6
of cd and cd	6
the cell surface and	6
the results of this	6
there was no statistically	6
tidal volume of ml	6
studies are required to	6
early phase of sepsis	6
of icu stay was	6
the endothelial cell surface	6
we did not find	6
in the immune response	6
in order to reduce	6
significant correlation between the	6
blood samples were drawn	6
sepsis in critically ill	6
sepsis campaign guidelines for	6
the confusion assessment method	6
for acute respiratory failure	6
were subjected to a	6
the first hours after	6
and the development of	6
infarction complicated by cardiogenic	6
groups a and b	6
probably due to the	6
in elderly patients with	6
values in patients with	6
of the role of	6
no significant difference was	6
in male wistar rats	6
with the help of	6
survival to hospital discharge	6
with a reduction in	6
logistic regression analysis was	6
organ failure assessment score	6
immune response to sepsis	6
american college of chest	6
a mortality rate of	6
was associated with the	6
in the process of	6
with the risk of	6
patients who survive sepsis	6
the first days after	6
with the occurrence of	6
should be taken into	6
resulted in a significant	6
a prospective study was	6
in the blood of	6
the adaptive immune response	6
the first time that	6
the intensive care units	6
blood samples were obtained	6
sepsis in patients with	6
used to assess the	6
it is well known	6
the production of pro	6
upon in vitro stimulation	6
one or more of	6
at all time points	6
we collected data from	6
than the control group	6
data was collected from	6
on a variety of	6
evaluate the effects of	6
despite the presence of	6
the intensity of the	6
by the fact that	6
on the severity of	6
a central venous catheter	6
sepsis was induced in	6
the early diagnosis of	6
of phage therapy in	6
despite the fact that	6
of organ dysfunction and	6
quality of life in	6
plasma of patients with	6
diagnosis of sepsis in	6
of tlr and tlr	6
patients were divided in	6
statistically highly significant difference	6
we found a significant	6
activation of the complement	6
the results showed that	6
discharge from the hospital	6
outcome in critically ill	6
was used to evaluate	6
quality of life and	6
emergency and critical care	6
in the french multicenter	6
human tumor necrosis factor	6
the management of patients	6
mean age was years	6
patients with severe community	6
the risk of death	6
of mortality in the	6
a broad range of	6
to severe sepsis in	6
acute lung injury in	6
the risk for sepsis	6
in order to evaluate	6
of the impact of	6
of renal replacement therapy	6
present study was designed	6
a sensitivity of and	6
patients with acute myocardial	6
was significantly associated with	6
on the immune system	6
to be one of	6
triggering receptor expressed on	6
test the hypothesis that	6
and the length of	6
c h hej mice	6
admission to the intensive	6
of septic shock and	6
it is apparent that	6
with increased morbidity and	6
significant differences were found	6
has been demonstrated in	6
it is necessary to	6
of the respiratory system	6
early diagnosis of sepsis	6
group and in the	6
at risk of developing	6
a diagnosis of sepsis	6
in a group of	6
observational study conducted in	6
it is possible to	6
the time of the	5
was induced in rats	5
the formation of the	5
in adult patients with	5
improve the outcome of	5
of bacteria in the	5
regression analysis showed that	5
no differences in the	5
and mortality of severe	5
clinical practice parameters for	5
retrospective cohort study of	5
in umbilical cord blood	5
age of years and	5
patients were diagnosed with	5
european society of intensive	5
all the patients were	5
mean arterial pressure of	5
multiple organ system failure	5
outcomes in critically ill	5
in patients undergoing cardiac	5
which can lead to	5
on the incidence of	5
as a diagnostic marker	5
in combination with other	5
the systemic infl ammatory	5
over the course of	5
was significantly increased in	5
also been shown to	5
pg ml to ng	5
to determine the incidence	5
organ dysfunction in sepsis	5
plasma levels of il	5
there was a trend	5
the difference between the	5
a tertiary care hospital	5
activated partial thromboplastin time	5
in the synthesis of	5
and regulation of the	5
mouse model of sepsis	5
data are given as	5
in of patients with	5
on the intensive care	5
goal of this study	5
the clinical course of	5
tidal volumes for acute	5
a significant difference in	5
to test this hypothesis	5
to be independent of	5
group of patients with	5
in traumatic brain injury	5
which may contribute to	5
has previously been shown	5
were found to have	5
cause of morbidity and	5
as a tool to	5
in intensive care medicine	5
have been proposed to	5
patients is associated with	5
be explained by the	5
that the level of	5
after the beginning of	5
as a means of	5
the signs and symptoms	5
the proportion of patients	5
working in icus with	5
in the septic shock	5
to treat patients with	5
patients with acute kidney	5
did not change significantly	5
the median number of	5
is defined as a	5
of sepsis on the	5
has not been investigated	5
to better understand the	5
higher in patients who	5
is also associated with	5
patients with severe head	5
brain microvascular endothelial cells	5
the results of our	5
with the control group	5
within hours before the	5
considered to be the	5
the presence of inhalation	5
the production of no	5
was performed in all	5
work is needed to	5
these studies suggest that	5
mortality rate in the	5
in a prospective observational	5
in patients with community	5
in patients with ali	5
tidal volumes as compared	5
in the peripheral blood	5
and outcome in patients	5
in patients with low	5
protein c and activated	5
the introduction of the	5
vascular cell adhesion molecule	5
the quality of care	5
a lethal dose of	5
in the dental practice	5
were the most common	5
may play an important	5
after intensive care unit	5
the levels of these	5
icu of a tertiary	5
the later stages of	5
administered to patients with	5
been implicated as a	5
the nalp infl ammasome	5
by a grant from	5
early onset neonatal sepsis	5
of organ dysfunction failure	5
have recently shown that	5
and sofa score were	5
the management of odontogenic	5
patients with cardiogenic shock	5
subclavian and internal jugular	5
mechanisms involved in the	5
septic shock is associated	5
compared with healthy controls	5
has been proposed that	5
septic shock in adults	5
the inflammatory response is	5
cacy and safety of	5
more of the following	5
the development of mods	5
the no sepsis cohort	5
and intensive care unit	5
first day of icu	5
rd esicm annual congress	5
immune system and the	5
the same dose of	5
the mechanism of action	5
with lower tidal volumes	5
leading cause of mortality	5
infectious diseases society of	5
in the amount of	5
the neonatal host response	5
chang gung memorial hospital	5
score in patients with	5
data from patients with	5
by sands et al	5
assess the impact of	5
compare the effects of	5
volumes for acute lung	5
granulocyte colony stimulating factor	5
epidemiology of sepsis and	5
of rio de janeiro	5
than in patients without	5
as compared with traditional	5
and adaptive immune responses	5
and the risk of	5
in patients with the	5
hemodynamic support of pediatric	5
compared to low dose	5
on the results of	5
levels were significantly lower	5
on the expression of	5
difference was observed in	5
endothelial function in sepsis	5
it is noteworthy that	5
the present study we	5
of patients presenting with	5
method for the intensive	5
role in the inflammatory	5
and apache ii score	5
ml to ng ml	5
of peripheral blood mononuclear	5
was not an independent	5
we found that the	5
it has been demonstrated	5
high performance liquid chromatography	5
our study suggests that	5
patients with liver cirrhosis	5
we have recently shown	5
the incidence of organ	5
significant differences between groups	5
task force of the	5
with mortality in critically	5
on the production of	5
ventilator dependence in the	5
to assess the efficacy	5
causes of death in	5
are associated with the	5
doses of hydrocortisone and	5
for up to days	5
lung injury and the	5
is defined as the	5
we aimed to compare	5
have been found to	5
endothelial cells in vitro	5
increased morbidity and mortality	5
in patients with elevated	5
injury and the acute	5
to one of the	5
of these patients had	5
and of patients were	5
the time of icu	5
b cm h o	5
by the administration of	5
there were no changes	5
effective antimicrobial therapy is	5
major cause of mortality	5
the general icu population	5
improves survival in sepsis	5
and central venous pressure	5
was significantly reduced in	5
in the multivariate analysis	5
patients years of age	5
the european society of	5
the cells of the	5
pressure and cardiac output	5
hypertension of the newborn	5
lactate requests in samples	5
early stage of sepsis	5
used to determine the	5
measured by means of	5
the changes in the	5
the correlation between the	5
the protocol used in	5
one of the following	5
in patients with suspected	5
plays an important role	5
were admitted in icu	5
modulates the expression of	5
the risk factors associated	5
arterial and venous blood	5
differences with respect to	5
the immune system to	5
were determined by elisa	5
were done by the	5
admission apache ii score	5
on the role of	5
in the levels of	5
quality of care in	5
with an incidence of	5
a good correlation between	5
persistent pulmonary hypertension of	5
and septic shock is	5
pulmonary hypertension of the	5
end of the study	5
response of the host	5
common in patients with	5
in this retrospective study	5
investigated the influence of	5
are thought to play	5
we would like to	5
mechanism of action of	5
in the detection of	5
outcome in these patients	5
was evaluated by the	5
at risk of ards	5
c h hen mice	5
treatment of infectious diseases	5
levels are associated with	5
compared with traditional tidal	5
in the rate of	5
is associated with the	5
and management in the	5
at the first day	5
was similar in both	5
cells of the immune	5
between the th and	5
pathogenesis of multiple organ	5
in the emergency room	5
associated with poor outcomes	5
the auc of the	5
and cm h o	5
the mortality rate was	5
as one of the	5
study is to examine	5
was higher than in	5
the role of tnf	5
as adjunctive therapy for	5
and outcomes of patients	5
mean values of il	5
a spontaneous breathing trial	5
were shown to be	5
patients who had undergone	5
support of pediatric and	5
for at least hours	5
the size of the	5
in the innate immune	5
in the host defense	5
to human tumor necrosis	5
th and th percentiles	5
the presence of shock	5
plays a pivotal role	5
in both groups but	5
to a reduction in	5
the risk of developing	5
in out of patients	5
at the cell surface	5
after major abdominal surgery	5
bei patienten mit kardiogenem	5
management in the adult	5
animals were sacrificed and	5
who died during the	5
the immune system and	5
activation of the contact	5
the pathogenesis of acute	5
lead to a reduction	5
admitted to the emergency	5
mobility group box protein	5
in experimental and clinical	5
mixed medical and surgical	5
for the intensive care	5
and treatment of infectious	5
could be a useful	5
with a variety of	5
be useful in the	5
was performed in a	5
compared to in the	5
patients did not meet	5
of acute and chronic	5
with high morbidity and	5
v d v t	5
significant difference was found	5
and length of hospital	5
in neonatal sepsis and	5
associated with a reduction	5
as a prognostic factor	5
sofa score at admission	5
it is not clear	5
were to determine the	5
to assess the incidence	5
the implementation of a	5
with the sepsis syndrome	5
lower tidal volumes as	5
to participate in the	5
were divided in two	5
assess the effect of	5
divided in two groups	5
over an average of	5
a significant correlation between	5
dysfunction in septic shock	5
the increased risk for	5
to the induction of	5
be administered to patients	5
shock is associated with	5
admitted to a medical	5
as a measure of	5
cm h o and	5
bacterial colonization of the	5
preterm and term infants	5
number of days of	5
antibody to human tumor	5
in a mixed medical	5
play a significant role	5
not meet any definitions	5
in patients with infection	5
of the effects of	5
production of inflammatory cytokines	5
sepsis to septic shock	5
a period of months	5
in order to improve	5
at onset of sepsis	5
in serum of patients	5
it was observed that	5
involvement was seen in	5
hours after the operation	5
our objective was to	5
we included patients with	5
alone or in combination	5
been associated with increased	5
the immune response of	5
severity of illness and	5
to evaluate the influence	5
used to evaluate the	5
we have found that	5
on the management of	5
patients with ali ards	5
length of mechanical ventilation	5
of circular rnas in	5
objective of our study	5
have been identified as	5
macrophages and dendritic cells	5
of health and welfare	5
subgroup of patients with	5
have the potential to	5
multiple organ dysfunction and	5
dysregulated host response to	5
and a decrease in	5
be taken into account	5
a common complication of	5
to the emergency room	5
mean arterial pressure and	5
was used for statistical	5
the severity of underlying	5
an essential role in	5
on the endothelial cell	5
sepsis is characterized by	5
in patients with and	5
of all patients admitted	5
median age was years	5
bei patienten mit schwerer	5
production of nitric oxide	5
cytokines such as il	5
aimed to investigate the	5
is the result of	5
as a predictor of	5
a neonatal intensive care	5
is a major cause	5
cd regulatory t cells	5
reduced the incidence of	5
in the respiratory tract	5
cochrane database syst rev	5
treatment with low doses	5
group compared to the	5
evaluate the influence of	5
innate immunity of the	5
the superior vena cava	5
to a lesser extent	5
mortality of patients with	5
c and activated protein	5
for the study of	5
nitric oxide synthase inhibitor	5
has been suggested to	5
an important cause of	5
it is not known	5
no differences were found	5
cohort study of patients	5
and activated protein c	5
with regard to the	5
role in host defense	5
to our intensive care	5
at baseline and after	5
with a combination of	5
and hospital length of	5
substanzen in der intensivmedizin	5
in the systemic inflammatory	5
monocyte human leukocyte antigen	5
differences were found between	5
found in patients with	5
with severe head injury	5
support the hypothesis that	5
the length of stay	5
not associated with the	5
least two of the	5
the patients were evaluated	5
sepsis incidence and mortality	5
of the coagulation system	5
there was also a	5
of the ventilator dependence	5
intensity of the inflammatory	5
should be aware of	5
increases the risk of	5
volumes as compared with	5
subset of patients with	5
thought to be a	5
the study was conducted	5
were admitted in the	5
are associated with a	5
ml in the control	5
the pathogenesis of multiple	5
the uk sepsis trust	5
at sites of inflammation	5
in patients with high	5
central role in the	5
such as tnf and	5
in the past decade	5
the plasma of patients	5
in murine polymicrobial sepsis	5
was found in the	5
a high incidence of	5
presence of inhalation injury	5
with severe traumatic brain	5
of pediatric and neonatal	5
is in line with	5
data suggest that the	5
contribute to the increased	5
cell death in patients	5
can lead to a	5
apache ii modified score	5
clinical trials in sepsis	5
were significantly decreased in	5
the need for a	5
leads to activation of	5
of systemic inflammatory response	5
the early stage of	5
low doses of hydrocortisone	5
assess the ability of	5
been studied in a	5
the absence of any	5
to be able to	5
no correlation was found	5
and mean arterial pressure	5
to be the most	5
observational study of patients	5
criteria for septic shock	5
that there was a	5
the production of cytokines	5
time of icu admission	5
further studies are required	5
an experimental model of	5
due to the presence	5
the time of diagnosis	5
and reactive oxygen species	5
on behalf of the	5
soluble triggering receptor expressed	5
were randomly allocated to	5
patients who met sepsis	5
in the early postoperative	5
the reasons for this	5
and the extent of	5
cells in vitro and	5
acute lung injury was	5
we have evaluated the	5
is due to a	5
the icu and hospital	5
due to lack of	5
the pathophysiology of neutropenic	5
diagnosis and management in	5
the host inflammatory response	5
development of th cells	5
risk of organ dysfunction	5
as well as il	5
the severity of illness	5
mortality in patients admitted	5
positive end expiratory pressure	5
with a high risk	5
that can be used	5
apache ii scores and	5
whole blood samples were	5
with increased risk of	5
such as tumor necrosis	5
number of sirs criteria	5
partial pressure of arterial	5
sepsis surviving sepsis campaign	5
in the field of	5
the objective of our	5
of the host immune	5
have the ability to	5
ventilation with lower tidal	5
our goal was to	5
inflammatory response in sepsis	5
to investigate whether the	5
compared to patients without	5
initial blood gas parameters	5
in patients with pneumonia	5
it was shown that	5
was not influenced by	5
a diagnosis of dementia	5
in the group with	5
human immunodeficiency virus infection	5
for the presence of	5
if they did not	5
implicated in the pathogenesis	5
to assess the ability	5
observed a decrease in	5
with suspected inhalation injury	5
the use of iggam	5
plays a major role	5
patients with acute renal	5
in the study by	5
more than hours in	5
the child with septic	5
preterm and term neonates	5
of the presence of	5
used in combination with	5
intensive care unit at	5
severity of the disease	5
statistically significant difference in	5
and mortality in patients	5
order to evaluate the	5
patients were treated with	5
and adaptive immune systems	5
traditional tidal volumes for	5
patients who died during	5
consumption of clotting factors	5
levels were significantly higher	5
the animals were sacrificed	5
the first few days	5
was significantly lower than	5
a patient with a	5
aktive substanzen in der	5
and its impact on	5
and most of the	5
patients with severe brain	5
patients on mechanical ventilation	5
inclusion and exclusion criteria	5
ventilator induced lung injury	5
have also been reported	5
the quality of life	5
of the lps receptor	5
at an early stage	5
and the degree of	5
number of patients with	5
acute phase proteins and	5
with traditional tidal volumes	5
acutely unwell ward patients	5
acute hypoxemic respiratory failure	5
incidence and outcome of	5
their discharge from the	5
patients with severe traumatic	5
to the activation of	5
in the perioperative period	5
of detect sepsis sensor	5
a broad spectrum of	5
to reduce the incidence	5
a prominent role in	5
of the intensive care	5
white blood cell counts	5
the context of sepsis	5
induced by cecal ligation	5
cd cd regulatory t	5
a prospective study in	5
the subsequent development of	5
was lower in patients	5
multiple linear regression analysis	5
admitted to critical care	5
in the era of	5
to evaluate the effects	5
were no differences between	5
as compared with adults	5
associated with a lower	5
mann whitney u test	5
the first three days	5
patients with bacteraemic sepsis	5
were used to determine	5
in an animal model	5
elevated in patients with	5
was found between the	5
of neutropenic fever and	5
male and female mice	5
be a useful tool	5
in sepsis and trauma	5
play a pivotal role	5
the united states from	5
of the multiple organ	5
is a frequent complication	5
mortality of septic shock	5
each of the four	5
septic shock due to	5
with high mortality rates	5
within hours of admission	5
with severe sepsis septic	5
of developmental age on	5
of the nitric oxide	5
to be responsible for	5
day mortality in septic	5
host immune response to	5
the efficacy and safety	5
the emergency department of	5
were compared with the	5
this retrospective study was	5
was observed in patients	5
the authors declare that	5
it is possible that	5
intensive care unit during	5
to the hypothesis that	5
ill patients with sepsis	5
prospective observational study in	5
pivotal role in the	5
ventilator dependence in patients	5
higher than the control	5
demographic and clinical data	5
diagnosis of sepsis is	5
area under roc curve	5
the nitric oxide synthase	5
of sepsis and its	5
number of organ dysfunctions	5
was to study the	5
prolonged mechanical ventilation in	5
patients with hematological malignancies	5
the overall incidence of	5
after the introduction of	5
to a lack of	5
critically ill adult patients	5
in the first group	5
which is known to	5
been shown to induce	5
more likely to be	5
in the group of	5
two dimensional gel electrophoresis	5
with a tidal volume	5
of diagnosis and management	5
significantly higher in group	5
the combination of the	4
showed an increase in	4
the major causes of	4
before and after surgery	4
cells were exposed to	4
did not affect the	4
a beneficial effect on	4
on day and day	4
it was the aim	4
who did not develop	4
with significant morbidity and	4
the average length of	4
presence of acute cerebral	4
of the pathogenesis of	4
are needed to clarify	4
failure in intensive care	4
admitted to an icu	4
not been investigated in	4
they did not meet	4
risk factor for a	4
the early postoperative period	4
of ischemic retinal oedema	4
in acute myocardial infarction	4
the specificity of the	4
to the icu for	4
the superior mesenteric artery	4
in a sensitivity analysis	4
may be a potential	4
requires the presence of	4
failure in critically ill	4
organ dysfunction failure in	4
been identified as a	4
nitrite and nitrate concentrations	4
and the level of	4
as the number of	4
if patients did not	4
proportion of perfused vessels	4
in clinical practice is	4
patients with suspected infection	4
levels in children with	4
of acutely unwell ward	4
organ dysfunction and failure	4
incidence of organ dysfunction	4
and soluble tnf receptors	4
patients who were not	4
multivariate logistic regression analysis	4
been shown to predict	4
use of mechanical ventilation	4
may be caused by	4
in patients with ventilator	4
significantly decreased in the	4
of the host response	4
ml cm h o	4
intensive care unit with	4
intensive care units of	4
the point of view	4
admitted to icu from	4
similar to that of	4
are believed to be	4
the expression of nf	4
initiation of effective antimicrobial	4
were expressed as median	4
the progression of sepsis	4
in the host response	4
patients with acute liver	4
and the effects of	4
oxygen delivery in the	4
to be the case	4
in the immune system	4
study in patients with	4
potent suppressors of the	4
not be used as	4
models of septic shock	4
early in the disease	4
cells in response to	4
were characterized by a	4
and treatment of neonatal	4
with the diagnosis of	4
were measured at the	4
severity of sepsis and	4
smart cuff manager tm	4
were higher in the	4
severe sepsis to septic	4
has been utilized in	4
diagnosis of septic shock	4
expressed on the endothelium	4
that the expression of	4
patients with clinical signs	4
neonatal host response to	4
patients with sepsis were	4
com content s s	4
and were more likely	4
were isolated from the	4
changes in patients with	4
the diameter of the	4
characteristics of the patients	4
increasing the risk of	4
worldwide evaluation in severe	4
the goal of our	4
clinical and laboratory findings	4
the need for mechanical	4
have to be considered	4
the definition of sepsis	4
and the activation of	4
not be used for	4
to assess the effect	4
in patients with mods	4
the presence of organ	4
and neonatal septic shock	4
has been implicated as	4
risk factors for early	4
associated with the occurrence	4
significantly different between the	4
correlation was observed between	4
sera from the rabbits	4
of the use of	4
it has been estimated	4
the incidence of bacterial	4
protein c worldwide evaluation	4
the increased expression of	4
was carried out on	4
in the period from	4
a summary of the	4
die of sepsis and	4
were less likely to	4
in line with the	4
a common complication in	4
is closely associated with	4
the duration of hospital	4
distribution of igm is	4
the duration of mechanical	4
cells of the innate	4
as shown in fig	4
and there was no	4
to play a major	4
ischemic cardiac slices were	4
survived to hospital discharge	4
to all patients admitted	4
the prevention and treatment	4
with ventilator dependence in	4
and septic shock the	4
endothelial cells have been	4
there was a decrease	4
of severe septic patients	4
the diagnosis and treatment	4
a positive correlation was	4
a corticotropin stimulation test	4
of brain microvascular endothelial	4
mortality in the intensive	4
increased the production of	4
in host defense against	4
expression of a number	4
sepsis has not been	4
which may lead to	4
mortality and length of	4
patients has not been	4
low molecular weight heparin	4
the contribution of the	4
plays a critical role	4
the early detection of	4
of a rapid response	4
lower than in the	4
the use of ivig	4
united states from through	4
the isth overt dic	4
we hypothesized that the	4
hospital mortality in patients	4
order to reduce the	4
is to examine the	4
significantly increased in the	4
college of chest physicians	4
remains one of the	4
not appear to be	4
severity of lung injury	4
in patients of the	4
to intensive care unit	4
involved in the production	4
patients with neutropenic fever	4
during the acute phase	4
that an increase in	4
proven infection in neonates	4
plasma from healthy volunteers	4
in order to minimize	4
serum levels of tnf	4
as the apache ii	4
a positive effect on	4
in the response to	4
were associated with increased	4
to evaluate the efficacy	4
of cytochrome c oxidase	4
investigated the relationship between	4
has been used to	4
critically ill medical patients	4
activation and recruitment of	4
of protein c and	4
findings of this study	4
the site of inflammation	4
useful or essential to	4
during the first months	4
similar to those of	4
one of the principal	4
previous studies have shown	4
groups c and d	4
to the increased risk	4
patients who developed septic	4
therapy in critically ill	4
patients in septic shock	4
cellular dysfunctions to immunotherapy	4
according to the sepsis	4
patients with sepsis to	4
was the most frequently	4
we have previously demonstrated	4
induced in rats by	4
patients were evaluated for	4
of intensive insulin therapy	4
were analysed by a	4
administration of activated protein	4
increased risk of death	4
a prospective clinical study	4
induced an increase in	4
is associated with adverse	4
airflow and airway pressure	4
critically ill patients a	4
results show that the	4
is part of the	4
a common disease in	4
of patients with multiple	4
a difference in the	4
statistically significant differences between	4
average length of stay	4
even in the absence	4
is related to the	4
to the occurrence of	4
to of the patients	4
reflect the severity of	4
days after icu admission	4
for preventing infection in	4
published maps and institutional	4
performed a retrospective observational	4
of infection in patients	4
as the result of	4
patients received mechanical ventilation	4
a continuous infusion of	4
we winning the battle	4
the role of complement	4
hydrocortisone reverse hyperdynamic septic	4
were used to assess	4
was not related to	4
for management of sepsis	4
mortality was higher in	4
d f and tgp	4
in published maps and	4
development and implementation of	4
in patients with bacteraemic	4
the need for mv	4
of central venous catheterization	4
two or more organ	4
of proinfl ammatory cytokines	4
animal models of sepsis	4
the mechanism by which	4
this work was supported	4
of the complement cascade	4
pressing strength and time	4
was no statistical significance	4
of a variety of	4
evaluation in severe sepsis	4
be taken into consideration	4
that the development of	4
organ failure in pediatric	4
arterial blood gases were	4
plasma levels of tnf	4
also been associated with	4
significantly higher in septic	4
the development of shock	4
results indicate that the	4
patients included in the	4
as a prognostic marker	4
of neonates with sepsis	4
response to injury and	4
and observed for hours	4
during extracorporeal membrane oxygenation	4
receptor for advanced glycation	4
to an intensive care	4
summary of the protocol	4
the development of an	4
of organ failure and	4
the risk of bleeding	4
neutrophil oxygen radical production	4
previously been shown to	4
mobilisation of the obese	4
to maintain a mean	4
was used to detect	4
a review of evidence	4
has been reported in	4
this is a retrospective	4
sepsis risk factors for	4
to evaluate the role	4
prospective observational cohort study	4
use of polyclonal immunoglobulins	4
an innate immune response	4
be used to diagnose	4
arterial and mixed venous	4
and symptoms of sepsis	4
general intensive care unit	4
first demonstration of a	4
in infants with sepsis	4
in newborn infants with	4
samples were tested for	4
than that of the	4
from septic patients and	4
is associated with worse	4
it appears that the	4
fever and neutropenic sepsis	4
patients with acute brain	4
h hej and c	4
intravenous immunoglobulin for suspected	4
is an important mediator	4
critically ill patients the	4
is important to note	4
in neonates is unknown	4
all patients who were	4
department of intensive care	4
recently it has been	4
critically ill patients who	4
experimental and clinical studies	4
developmental age on the	4
were admitted in our	4
of severe sepsis was	4
the magnitude of the	4
and it has been	4
clinically or microbiologically documented	4
insulin therapy in the	4