Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-252456-971d0sirPathog Dis Novel coronavirus takes flight from bats?
cord-257587-xjoyrdhjThe two- pore channel TPCN2 mediates NAADPdependent Ca(2+)-release from lysosomal stores Convergent regulation of the lysosomal two- pore channel-2 by Mg(2)(+), NAADP, PI(3,5)P(2) and multiple protein kinases Expression of Ca(2)(+)-permeable two- pore channels rescues NAADP signalling in TPC- deficient cells TPC: the NAADP discovery channel?
cord-256784-wfaqim7dDistinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-263508-row2mn17Introduction: the"new SARS"?
cord-259703-9ef3u2mzClinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection Clinical management of severe acute respiratory infection when Middle East respiratory syndrome coronavirus( MERS- CoV) infection is suspected-Interim guidance Hypoxaemic rescue therapies in acute respiratory distress syndrome: Why, when, what and which one?
cord-259347-3acsko74Is SARS- CoV-2 likely to be present in the central nervous system?
cord-259658-rgrt6e6rthe beginning of another SARS- like pandemic?
cord-265282-v3n9ff16When is quarantine a useful control strategy for emerging infectious diseases?
cord-007828-c7jxj74b: cord-007828-c7jxj74b authors: Memish, Ziad A.; Al- Tawfiq, Jaffar A. title: Middle East respiratory syndrome coronavirus infection control: The missing piece?
cord-007828-c7jxj74bWhich preventive measures might protect health care workers from SARS?
cord-265380-2gs34xcwTherefore, the first question in generating a MERS- CoV animal model would be: What are the pathological features of a human infection?
cord-264199-8skyagszCan closure of live poultry markets halt the spread of H7N9?
cord-016842-sow7k53mDefining Customer- Centered Systems Latent dirichlet allocation Statistical Inference Can cascades be predicted?
cord-016842-sow7k53mThe anatomy of large Facebook cascades News in online and print newspapers: differences in reader consumption and recall The structural virality of online diffusion Hard wired for negative news?
cord-266987-ikt8r2o1Exclusivity testing showed that 229E, OC43 and MERS, 229E, HKU1, NL63, OC43 yielded negative results( https://www.who.int/docs/defaultsource/coronaviruse/peiris-protocol-16-1-20.pdf?
cord-103739-mmkrwj8tDo viruses subvert cholesterol 863 homeostasis to induce host cubic membranes?
cord-103739-mmkrwj8tReplication Organelle Comprises Double- Membrane Vesicles and Zippered Endoplasmic 766 Does form meet function in the 769 coronavirus replicative organelle?
cord-255339-oudj079qAn undescribed virus disease of sheep cattle and man from East Africa Has Rift Valley fever virus evolved with increasing severity in human populations in East Africa?
cord-255339-oudj079qWill Egypt be the epicenter of the next influenza pandemic?
cord-255815-5d9bqji0= y 0?
cord-255815-5d9bqji0a/(1?
cord-271244-6m8sbbi1and now the 2019-novel CoV: Have we investigated enough about coronaviruses?
cord-256020-wrui3i2lThe importance of recognising early possible ocular manifestation and using protective eyewear Can the Coronavirus Disease 2019( COVID-19) affect the eyes?
cord-256020-wrui3i2lWorldometers( https://www. worldometers.info/coronavirus/?).
cord-266031-tlrsco40Can new tools keep them afloat?
cord-266031-tlrsco40Mapping the science behind ebola Estimation of covid-19 dynamics"on a back- of- envelope": Does the simplest sir model provide quantitative parameters and predictions?
cord-260024-yrhlg6wmIntroduction to continuity of operations planning for pandemic influenzas MERS in South Korea and China: a potential outbreak threat?
cord-260024-yrhlg6wmWhat can we learn from MERS outbreak in South Korea?
cord-273182-djb0ozrtSituation update worldwide Global patterns in coronavirus diversity Sars- CoV-2 envelope and membrane proteins: structural differences linked to virus characteristics?
cord-275404-hv3y4x4gWhy did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-258323-vdeffy4lAn anti- inflammatory function for the complement anaphylatoxin C5a- binding protein, C5L2 Extrahepatic complement biosynthesis: Where, when and why?
cord-258323-vdeffy4lNLRP3 Inflammasome NLRP3 is Required for Complement- Mediated Caspase-1 and IL-1beta Activation in ICH Intracellular complement activation- An alarm raising mechanism?
cord-263016-28znb322: what lessons can we learn?
cord-263016-28znb322What lessons can we learn after three years of clinical experience and scientific research?
cord-271723-8qoozmgkShould Clinicians Use chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or treatment of COVID-19?
cord-277781-v9hw1cdiHow sensitive within assumed parameter range?
cord-274122-n9jnu2ahdeubiquitinase inhibitors blocks SARS virus replication Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain- like protease?
cord-257511-4ftedh1aAre TPCs druggable targets for antiviral development?
cord-257511-4ftedh1aCan TPC modulators attenuate MERS trafficking through the endolysosomal system?
cord-257511-4ftedh1aHow do TPCs support MERS passage from cell surface to cytoplasm?
cord-274007-zndtddtyCan coronavirus pass from mother to baby?
cord-024569-d9opzb6mThe impact of communications about swine flu( influenza A H1N1v) on public responses to the outbreak: Results from 36 national telephone surveys in the UK Scary warnings and rational precautions: A review of the psychology of fear appeals Social media as a useful tool in food risk and benefit communication?
cord-024569-d9opzb6mTherefore, it is worth investigating how the cognitive, emotional, and behavioral responses to social media use differ from those to traditional media use, which raises the following research question: Are there any differences between traditional media use and social media use in terms of cognitive, emotional, and behavioral responses during the MERS crisis?
cord-024569-d9opzb6mWhat, me worry?
cord-271004-gtmo5ixsMERS- CoV Statistics n Hospital- Associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description Middle East respiratory syndrome coronavirus in healthcare settings Middle East respiratory syndrome coronavirus infection control: the missing piece?
cord-271004-gtmo5ixskingdom of Saudi Arabia Molecular epidemiology of hospital outbreak of Middle East respiratory syndrome Presentation and outcome of Middle East respiratory syndrome in Saudi intensive care unit patients Notes from the field: nosocomial outbreak of Middle East respiratory syndrome in a large tertiary care hospital- Riyadh, Saudi Arabia Drivers of MERS- CoV transmission: what do we know?
cord-277337-ij0dn77hCho, Hae- Wol; Chu, Chaeshin title: Outbreak of Middle East Respiratory Syndrome in Korea?
cord-278939-z6kiee09Can Chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-280029-g1k3zlaxCOVID-19: what is next for public health?
cord-279557-hk77e3ppA simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood Family cluster of Middle East Respiratory Syndrome coronavirus infections Detection of herpes simplex virus DNA by real- time PCR Real- time reverse transcription- PCR assay for comprehensive detection of human rhinoviruses Respiratory herpes simplex virus type 1 infection/ colonisation in the critically ill: marker or mediator?
cord-279503-w4tn03w0Design of Gold Nanoparticle- Based Colorimetric Biosensing Assays Spontaneously formed sulfur adlayers on gold in electrolyte solutions: Adsorbed sulfur or gold sulfide?
cord-271211-frkk6w0aViral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection Enteric involvement of coronaviruses: is faecal- oral transmission of SARS- CoV-2 possible?
cord-271211-frkk6w0aWhat are the risks of COVID-19 infection in pregnant women?
cord-267001-csgmc155The adjuvant GLA- SE promotes human Tfh cell expansion and emergence of public TCRbeta clonotypes Can follicular helper T cells be targeted to improve vaccine efficacy?
cord-267001-csgmc155Where is the cut- off?
cord-255628-bm4nogigFurthermore, in communities in which Ebola transmission might be ongoing, an important question is: how will such a vaccination be perceived if a vaccinated person develops Ebola?
cord-255628-bm4nogigThese developments are worrisome given Favipiravir- a prophylactic treatment for Ebola contacts?
cord-255628-bm4nogigauthors: Su, Shuo; Wong, Gary; Liu, Yingxia; Gao, George F; Li, Shoujun; Bi, Yuhai title: MERS in South Korea and China: a potential outbreak threat?
cord-268388-kkhuzf3pEpidemic potential or a storm in a teacup?
cord-268388-kkhuzf3pWhat are our pharmacotherapeutic options for MERS- CoV?
cord-271648-m2c5bvujA Review of Virus- Host Interactions Human coronaviruses: What do they cause?
cord-271648-m2c5bvujmedRxiv 2020 Comparing mask fit and usability of traditional and nanofibre N95 filtering facepiece respirators before and after nursing procedures A close shave?
cord-253077-61fmul8c( COVID-19): A Review Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-253077-61fmul8c:( 1) what is the contribution of T cells to initial virus control and tissue damage in the context of COVID-19, and( 2) how do memory T cells established thereafter contribute to protective immunity upon re- infection?
cord-253077-61fmul8cCytoplasmic Origin SARS- CoV-2 is sensitive to type I interferon pretreatment Prediction and Evolution of B Cell Epitopes of Surface Protein in SARS- CoV-2 Serology characteristics of SARS- CoV-2 infection since the exposure and post symptoms onset Quantifying treatment effects of hydroxychloroquine and azithromycin for COVID-19: a secondary analysis of an open label non- randomized clinical trial Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Adjuvant corticosteroid therapy for critically ill patients with COVID-19( medRxiv) Meta- Analysis: Convalescent Blood Products for Spanish Influenza Pneumonia: A Future H5N1 Treatment?
cord-282554-hlcgutzfWhat do you expect this nCoV outbreak to be in the future?
cord-282293-pdhjl508Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study What needs to be done to control the spread of Middle East respiratory syndrome coronavirus?
cord-283586-o8m6xdraWhat are our pharmacotherapeutic options for MERS- CoV?
cord-279733-c0w9bw5uDelayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis Distinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-261876-7rsc803xDoes SARS- CoV-2 has a longer incubation period than SARS and MERS?
cord-261876-7rsc803xNL63: a clinically important virus?
cord-261876-7rsc803xwhen is an exposed individual known to be disease free?
cord-286472-pqtem19t: what lessons can we learn?
cord-280941-ds6x0yymHow will HPV vaccines affect cervical cancer?
cord-280941-ds6x0yymThe composition and the structure of bacterioferritin of Escherichia coli Self- assembly in the ferritin nano- cage protein superfamily Presenting native- like trimeric HIV-1 antigens with self- assembling nanoparticles Hemagglutinin- stem nanoparticles generate heterosubtypic influenza protection Ferritin nanocages: great potential as clinically translatable drug delivery vehicles?
cord-276193-cngz535oA pandemic warning?
cord-276193-cngz535oimproves the immunogenicity of modified vaccinia virus Ankara expressing HIV-1 antigens Designing cell lines for viral vaccine production: where do we stand?
cord-285900-3rr0j5tkHow can we quantitatively evaluate the epitopes'neutralizing immunogenicity?
cord-286631-3fmg3scxA familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person- toperson transmission: a study of a family cluster Responding to Covid-19-A once- in- a- century pandemic?
cord-267090-jc1k3fkiIn this regard, case- crossover studies answer the question"why now?"as opposed to"why these subjects?"[ 17].
cord-267090-jc1k3fkiIn this regard, case- crossover studies answer the question"why now?"as opposed to"why these subjects?"[ 17].
cord-267090-jc1k3fkiShould we use a case- crossover design?
cord-104500-m0kfom0xEvents Soluble Receptor Potentiates Receptor- Independent Infection by Murine Coronavirus Heterogeneities in the transmission of infectious agents: Implications for the design of control programs Identification of a Novel Antibody Associated with Autoimmune Pancreatitis Helicobacter pylori and autoimmune pancreatitis: role of carbonic anhydrase via molecular mimicry?
cord-104500-m0kfom0xGenomic and protein structure modelling analysis depicts the origin and infectivity of 2019-nCoV COVID-19, SARS and MERS: are they closely related?
cord-104500-m0kfom0xThe 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China Convalescent plasma in Covid-19: Possible mechanisms of action COVID-19 âȂŤ toward a comprehensive understanding of the disease Time course quantitative detection of SARS- CoV-2 in Parisian wastewaters correlates with COVID-19 confirmed cases Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin Cannabidiol as prophylaxis for SARS- CoV-2 and COVID-19? Unfounded claims versus potential risks of medications during the pandemic Amplification of the basic reproduction number in cattle farm networks
cord-104500-m0kfom0xWhy Systematic Review rather than Narrative Review?
cord-291590-24psoaerQatar Drivers of MERS- CoV transmission: what do we know?
cord-284845-on97zu6wDistinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-284845-on97zu6wthe major drug targets of the twenty- first century?
cord-256537-axbyav1mBut, what of influenza?
cord-256537-axbyav1mIs it simply that we are more able, with our new technologies, to detect them?
cord-256537-axbyav1mOr are there forces at work that are fostering this trend?
cord-256537-axbyav1mSo what explains the apparent increased pace of emergence of new human infections?
cord-288859-19jwawrmMathematical models to characterize early epidemic growth: a review Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions Emergency response to a smallpox attack: the case for mass vaccination Could widespread use of combination antiretroviral therapy eradicate HIV epidemics?
cord-252049-rgdynmlaAre higher levels of expression of 3CL pro in MERS- CoV- infected cells necessary to allow formation of active dimer?"Are other mechanisms such as substrate- or ligand- induced dimerizations involved in activating 3CL pro?
cord-252049-rgdynmlaAre higher levels of expression of 3CL pro in MERS- CoV- infected cells necessary to allow formation of active dimer?"Are other mechanisms such as substrate- or ligand- induced dimerizations involved in activating 3CL pro?
cord-252049-rgdynmlaIs dimerization required for the catalytic activity of bacterial biotin carboxylase?
cord-252049-rgdynmlathe beginning of another SARS- like pandemic?
cord-271512-owidim7oDoes this mean that MERS- CoV is mainly an adult disease?
cord-271512-owidim7oOr alternatively, does MERS- CoV in children have a different clinical picture, including a less severe disease, or an atypical presentation, or even an asymptomatic carrier state?
cord-271512-owidim7oWhat are the risk factors, the comorbidities and the outcome?
cord-294349-ps3qlho2They are a large family of singlestranded RNA viruses(? ssRNA) that can be isolated from different animal species.
cord-268483-joiajgs4: what to expect for COVID-19?
cord-268483-joiajgs4: where are we?
cord-268483-joiajgs4Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-268483-joiajgs4Clinical features of patients infected with 2019 novel coronavirus in Wuhan A phase 3, single- arm, prospective study of remestemcel- l, ex vivo culture- expanded adult human mesenchymal stromal cells for the treatment of pediatric patients who failed to respond to steroid treatment for acute graft- versus- host disease Remestemcel- L: Human mesenchymal stem cells as an emerging therapy for Crohn's disease Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia Mesoblast To Evaluate Anti- Inflammatory Cell Therapy Remestemcel- L for Treatment of Covid-19 Lung Disease Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-280350-ay4cnzn5: what have we learned?
cord-280350-ay4cnzn5Antiviral or proviral action of mycophenolic acid in hepatitis B infection?
cord-280350-ay4cnzn5Bioequivalence of enteric- coated mycophenolate sodium and mycophenolate mofetil: a metaanalysis of three studies in stable renal transplant recipients Ribavirin in the treatment of SARS: a new trick for an old bug?
cord-103899-6tqm99g1COVID-19, SARS and MERS: are they closely related?
cord-103899-6tqm99g1MicroRNAs in inflammatory lung disease- master regulators or target practice?
cord-103899-6tqm99g1The role of microRNAs in respiratory viral infection: friend or foe?
cord-103899-6tqm99g1The role of microRNAs in respiratory viral infection: friend or foe?
cord-103899-6tqm99g1targeting TGFβ1 enhances antimicrobial capacity in Mycobacterium tuberculosis infected mice COVID-19 in the heart and the lungs: could we"Notch"the inflammatory storm?
cord-278182-75u57fw1Predicting binding regions within disordered proteins Sequence complexity of disordered protein Mining alpha- helix- forming molecular recognition features with cross species sequence alignments Coupled folding and binding with alpha- helix- forming molecular recognition elements Viral disorder or disordered viruses: do viral proteins possess unique features?
cord-278182-75u57fw1Since both SARS- CoV and SARS- CoV-2 have intermediate respiratory transmission potentials, how do we account for the greater contagiousness of the latter?
cord-278182-75u57fw1Why are"natively unfolded"proteins unstructured under the physiological conditions?
cord-286072-kgpvdb42: What Do They All Do?
cord-286072-kgpvdb42How the SARS coronavirus causes disease: host or organism?
cord-291367-rtmsrh16An update on Middle East respiratory syndrome: 2 years later Pilgrims and MERS- CoV: what's the risk?
cord-287886-41isp0wj: what do we know?
cord-287886-41isp0wjIs the epidemic changing?
cord-293505-1t3hg4wiHome care for patients with Middle East respiratory syndrome coronavirus( MERS- CoV) infection presenting with mild symptoms and management of contacts?
cord-295633-vkjcheazWhat have we learned about Middle East respiratory syndrome coronavirus emergence in humans?
cord-295375-nakxfhxkPrevalence of comorbidities in the Middle East respiratory syndrome coronavirus( MERS- CoV): a systematic review and meta- analysis Prevalence of diabetes in the 2009 influenza A( H1N1) and the Middle East respiratory syndrome coronavirus: a systematic review and meta- analysis A systematic, thematic review of social and occupational factors associated with psychological outcomes in healthcare employees during an infectious disease outbreak Effect of integrated traditional Chinese medicine and western medicine on the treatment of severe acute respiratory syndrome: a meta- analysis What have we learned about Middle East respiratory syndrome coronavirus emergence in humans?
cord-265666-27ckjl7wWhat are the challenges of working during the MERS outbreak?
cord-265666-27ckjl7wWhat are your working experiences of caring for suspected or infected patients with MERS during the outbreak?
cord-265666-27ckjl7wWhy do you have to do it, and what if you are infected?
cord-265666-27ckjl7wWhy does it have to be you?
cord-265666-27ckjl7wWhy?
cord-255378-qgklt8waBacteria of the E. coli strain BL21(DE3) transformed with the pET-28a(?)
cord-255378-qgklt8waHeteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients TALOS?
cord-255378-qgklt8waPositive and negative values of the difference between DdCa and DdCb correspond to a- helix and b- sheet secondary structure, respectively and correlated well with TALOS?
cord-255378-qgklt8waSecondary structure elements of MERS- CoV macro domain were identified by calculating the chemical shift deviations of the Ca(DdCa) and Cb(DdCb) from the random coil values and was corroborated by analysis of the chemical shift data using the program TALOS?
cord-255378-qgklt8waXhoI site of pET-28a(?)
cord-266260-t02jngq0Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission Enhanced MERS coronavirus surveillance of travelers from the Middle East to England Control of an Outbreak of Middle East Respiratory Syndrome in a Tertiary Hospital in Korea Molecular Evolution of MERS Coronavirus: Dromedaries as a Recent Intermediate Host or Long- Time Animal Reservoir?
cord-266260-t02jngq0If a MERS- CoV occurrence was assigned a buffer, what is the radius in km?
cord-266260-t02jngq0What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans?
cord-266260-t02jngq0Which type of polygon was used to geo- position the occurrence?
cord-266260-t02jngq0poly_type: If the MERS- CoV occurrence was assigned a shape_type of polygon, was it admin( GAUL), custom, or buffer?
cord-294656-sx3tpe0yMiddle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility Outbreak of Middle East respiratory syndrome in Korea?
cord-294907-i836d6imwhat lessons have we learned?
cord-291694-nokowfdiHas passenger traveled to, or resided in, the Arabian peninsula or a neighboring country in the 14 days prior to onset of illness?
cord-291694-nokowfdiIs this for anybody returning from a Gulf State or only those returning with symptoms?
cord-297418-36j840wmWhat's New With the Old Coronaviruses?
cord-297954-87w2itin2 years later Middle East respiratory syndrome coronavirus infection control: the missing piece?
cord-264408-vk4lt83x( l- sIGN) is a receptor for severe acute respiratory syndrome coronavirus Glycomic characterization of respiratory tract tissues of ferrets: implications for its use in influenza virus infection studies Comparative analysis of monkeypox virus infection of cynomolgus macaques by the intravenous or intrabronchial inoculation route Phenotypic changes in langerhans'cells after infection with arboviruses: a role in the immune response to epidermally acquired viral infection?
cord-264408-vk4lt83xA novel model of lethal Hendra virus infection in African green monkeys and the effectiveness of ribavirin treatment Clinical outcome of henipavirus infection in hamsters is determined by the route and dose of infection recent progress in henipavirus research: molecular biology, genetic diversity, animal models Mucosal arenavirus infection of primates can protect them from lethal hemorrhagic fever sArs vaccines: where are we?
cord-264408-vk4lt83xA simple technique for infection of mosquitoes with viruses; transmission of Zika virus Human papillomavirus research: do we still need animal models?
cord-264408-vk4lt83xAn unusual hantavirus outbreak in southern Argentina: person- to- person transmission?
cord-264408-vk4lt83xemerg sArs: what have we learned?
cord-296517-414grqifHave Super- Spreaders Played a Role in Other Outbreaks?
cord-291014-cfnoxhtdH3 stalk-a challenge for broad- spectrum vaccines?
cord-291014-cfnoxhtdImmune response: protective or pathogenic?
cord-299720-f0ny4ur5Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-227268-8k9zaqsyHere is a simple( non- rigorous?) derivation of the extinction probabilities for the Markov version of the SS epidemic without sporadic cases.
cord-227268-8k9zaqsyHowever, does that mean the authors'conclusion is wrong?
cord-227268-8k9zaqsySo why the resort to programming the laptop?
cord-227268-8k9zaqsySp- int is hard to estimate, because it is difficult to distinguish sporadic from secondary cases; e.g., if in a family a father and two children become infected and the father becomes ill first, should the children be counted as secondary cases, or were they exposed to the same external source of virus and so additional sporadic cases?
cord-227268-8k9zaqsyWhat could be the meaning of this EPV?
cord-227268-8k9zaqsyWhy ca n't we use the informal argument for the general case( without requiring everything to be exponential)?
cord-294831-pem059zkNew insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
cord-294831-pem059zkWhat caused lymphopenia in SARS and how reliable is the lymphokine status in glucocorticoid- treated patients?
cord-299986-wuaxatrbauthors: Afsar, Nasir Ali title: The looming pandemic of COVID-19: What therapeutic options do we have now?
cord-287156-3plpi6i9A New Vasculitis at the time of COVID-19 A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China Corona Virus Disease 2019, a growing threat to children?
cord-287156-3plpi6i9Can Influence the Clinical Treatment of Pregnant Women With COVID-19 Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies Outcome of Coronavirus spectrum infections( SARS, MERS, COVID 1-19) during pregnancy: a systematic review and meta- analysis Perinatal Transmission of COVID-19 Associated SARS- CoV-2: Should We Worry?
cord-287156-3plpi6i9Wkly Rep Are children less susceptible to COVID-19?
cord-292836-1o2ynvy3Human coronavirus OC43 associated with fatal encephalitis Detection of coronavirus in the central nervous system of a child with acute disseminated encephalomyelitis The role of human coronaviruses in children hospitalized for acute bronchiolitis, acute gastroenteritis, and febrile seizures: a 2-year prospective study Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?
cord-292836-1o2ynvy3What ’s New With the Old Coronaviruses?
cord-294854-rvrgcugnCOVID-19) 2020 COVID-19, SARS and MERS: are they closely related?
cord-294854-rvrgcugnThe Journal of infection Hydroxychloroquine inhibits CD154 expression in CD4 T lymphocytes of systemic lupus erythematosus through NFAT, but not STAT5, signaling Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-305582-3hmsknonYu Ping Feng San, an ancient Chinese herbal decoction, induces gene expression of anti- viral proteins and inhibits neuraminidase activity Oseltamivir compared with the Chinese traditional therapy maxingshigan- yinqiaosan in the treatment of H1N1 influenza: a randomized trial Convalescent plasma: new evidence for an old therapeutic tool?
cord-305773-ikm1famjWhat can we learn from MERS outbreak in South Korea?
cord-296026-6qtip2gaHow can we do better next time?
cord-296026-6qtip2gaWhat could we have done better?
cord-286741-h3oix9zcHistory of swine influenza viruses in Asia Genetics, evolution, and the zoonotic capacity of European swine influenza viruses Sowing the seeds of a pandemic?
cord-286741-h3oix9zcHowever, DPP4 of frequently used small The designation of"O"means that there are many studies using the animal for the purposed study The designation of"?"means that there are no or not many studies using the animal for the purposed study animal models like mouse, hamster, and ferret did not bind to MERS- CoV[ 128].
cord-286741-h3oix9zcThe designations of"O"and"?"are the same as in Table 1 appeared to be well replicated( 59/63) in the middle or lower respiratory tract, regardless of the presence of swine PB2 or avian PB2, although all but one reassortants( 62/63) contained the swine HA.
cord-304943-thg4fqi2How will country- based mitigation measures influence the course of the COVID-19 epidemic?
cord-292041-a65kfw80Has patient technique improved over time?
cord-292041-a65kfw80Phase I clinical trial of fenretinide( NSC374551) in advanced solid tumors Quis Custodiet Ipsos Custodes?
cord-292041-a65kfw80Sci Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19 SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS- Coronavirus infection Autophagy and viruses: Adversaries or allies?
cord-304030-6ve5plea: can we go from bench to bedside?
cord-298773-vnmc6nqd: cord-298773-vnmc6nqd authors: Pfeiffer, Julie K. title: Is the Debate and “ Pause ” on Experiments That Alter Pathogens with Pandemic Potential Influencing Future Plans of Graduate Students and Postdoctoral Fellows?
cord-298773-vnmc6nqdFor example, factoring in retirement rates and potential loss of future investigators, what will the influenza/ MERS/ SARS virus fields look like in 2030, 2040, or 2050?
cord-307067-cpc1yefjA phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime-MVA85A boost in healthy UK adults Safety and immunogenicity of a heterologous prime- boost ebola virus vaccine regimen in healthy adults in the united kingdom and senegal Middle East respiratory syndrome coronavirus( MERS- CoV) causes transient lower respiratory tract infection in rhesus macaques MERS- CoV spillover at the camel- human interface Recovery from the Middle East respiratory syndrome is associated with antibody and T- cell responses Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus( MERS- CoV) after experimental infection Absence of MERS- CoV antibodies in feral camels in Australia: Implications for the pathogen's origin and spread Middle East respiratory syndrome coronavirus antibodies in Dromedary Camels Serologic evidence for MERS- CoV infection in Dromedary Camels Molecular evolution of MERS coronavirus: Dromedaries as a recent intermediate host or long- time animal reservoir?
cord-301730-flv5lnv8However, was COVID-19 an unexpected viral pandemic?
cord-301730-flv5lnv8What Does Plant- Based Vaccine Technology Offer to the Fight against COVID-19?
cord-284234-9cd2v6bt( Table 2) COVID-19, SARS and MERS: are they closely related?
cord-284234-9cd2v6btFronts of Medicine ACE2 expression by colonic epithelial cells is associated with viral infection, immunity and energy metabolism Imbalance of the renin- angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?
cord-284234-9cd2v6btThe facts the third epidemic Case report of COVID-19 in a kidney transplant recipient: Does immunosuppression alter the clinical presentation?
cord-284234-9cd2v6btis not a reason for concern Incidence of hepatitis B virus reactivation in patients with resolved infection on immunosuppressive therapy for rheumatic disease: a multicentre, prospective, observational study in Japan High viral load and respiratory failure in adults hospitalized for respiratory syncytial virus infections Immunosuppression for hyperinflammation in COVID-19: a double edged sword?
cord-284234-9cd2v6btp t Immunosuppressive drugs and severity of coronavirus infections: opportunity in the face of adversity?
cord-300078-svu06v9cCan new tools keep them afloat?
cord-300078-svu06v9cMapping the science behind ebola Estimation of covid-19 dynamics"on a back- of- envelope": Does the simplest sir model provide quantitative parameters and predictions?
cord-260518-mswb3q67Are animal vaccination strategies economically viable given the large number of imported animals and the frequency of the infection?
cord-260518-mswb3q67Are there particular regions of Africa that provide infected camels to Saudi Arabia?
cord-260518-mswb3q67Emerging infectious diseases and pandemic potential: status quo and reducing risk of global spread Development of medical countermeasures to Middle East respiratory syndrome coronavirus What is One Health?
cord-260518-mswb3q67Is there a way to efficiently control the entry of infected camels?
cord-260518-mswb3q67Or is there a general risk from all regions?
cord-260518-mswb3q67Questions remain, for example are new local MERS outbreaks in Saudi Arabia always seeded by the same type of human exposure to camels?
cord-260518-mswb3q67missed opportunities for Europe- Africa research Rapid spread of Zika virus in the Americas- implications for public health preparedness for mass gatherings at the 2016 Brazil Olympic Games Lessons from the Ebola outbreak: action items for emerging infectious disease preparedness and response Challenges in controlling the Ebola outbreak in two prefectures in Guinea: why did communities continue to resist?
cord-312692-jv3425w1Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte- derived macrophages and dendritic cells Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of Middle East respiratory syndrome coronavirus infection in the United Arab Emirates Kinetics and pattern of viral excretion in biological specimens of two MERS- CoV cases Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection Updates in the management of acute lung injury: a focus on the overlap between AKI and ARDS MERS transmission and risk factors: a systematic review Distinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-312691-ynh84b98Middle East Respiratory Syndrome( MERS) or influenza?
cord-297062-dmiplvt2: how close are we?
cord-297062-dmiplvt2Epidemiological update: Middle East respiratory syndrome coronavirus?
cord-297062-dmiplvt2Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea Middle East respiratory syndrome coronavirus( MERS- CoV): what lessons can we learn?
cord-311937-6hadssmhLessons learnt Travel- related MERS- CoV cases: an assessment of exposures and risk factors in a group of Dutch travellers returning from the Kingdom of Saudi Arabia EDs on heightened alert for MERS- CoV as first cases reach the US Middle East respiratory syndrome coronavirus( MERS- CoV) infections in two returning travellers in the Netherlands Middle East respiratory syndrome coronavirus( MERS- CoV): what lessons can we learn?
cord-307109-nz8qvuw6convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-271504-t3y1w9ef, its homologue ACE2 and neprilysin in angiotensin peptide metabolism COVID-19 and angiotensinconverting enzyme inhibitors and angiotensin receptor Blockers Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-271504-t3y1w9ef: lessons from severe acute respiratory syndrome and Middle East respiratory syndrome Radiology of severe acute respiratory syndrome( SARS): the emerging pathologic- radiologic correlates of an emerging disease Middle East respiratory syndrome coronavirus: what does a radiologist need to know?
cord-271504-t3y1w9efA human monoclonal antibody blocking SARS- CoV-2 infection Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes IgM in microbial infections: taken for granted?
cord-271504-t3y1w9efThe SARS- coronavirus papain- like protease: structure, function and inhibition by designed antiviral compounds Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate- like Aza- peptide Epoxide Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry Protease inhibitors targeting coronavirus and filovirus entry Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective?
cord-271504-t3y1w9efThe broad- spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen Signatures of nucleotide analog incorporation by an RNA- dependent rna polymerase revealed using high- throughput magnetic tweezers Ribavirin in the treatment of SARS: a new trick for an old drug?
cord-271504-t3y1w9efWhat happens to people's lungs when they get coronavirus?
cord-309518-seonrtn3Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-314357-u1m7yr8fThe quest for public health security at Hajj: the WHO guidelines on communicable disease alert and response during mass gatherings Are Saudi medical students aware of middle east respiratory syndrome coronavirus during an outbreak?
cord-313028-0nhgxoima descriptive study Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome MERS- CoV infection in humans is associated with a pro- inflammatory Th1 and Th17 cytokine profile Expression of elevated levels of pro- inflammatory cytokines in SARS- CoV- infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS Distinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-316013-7dckgg6bthe beginning of another SARS- like pandemic?
cord-278839-uu2wlpmpRespiratory viruses and sudden infant death Evaluation of maternal mortality under- reporting in the heights of Chiapas using the RAMOS and modified RAMOS strategies Maternal immunisation: what have been the gains?
cord-278839-uu2wlpmpThe expression and localization of the human placental prorenin/ renin- angiotensin system throughout pregnancy: roles in trophoblast invasion and angiogenesis?
cord-278839-uu2wlpmpViral infections and the neonatal brain Age- specific incidence of influenza A responds to change in virus subtype dominance Pulmonary susceptibility of neonates to respiratory syncytial virus infection: a problem of innate immunity?
cord-278839-uu2wlpmpWhat does the future hold?
cord-278839-uu2wlpmpWhere are the gaps?
cord-278839-uu2wlpmprole of glucocorticoids Hertz- Picciotto I. Is maternal influenza or fever during pregnancy associated with autism or developmental delays?
cord-317389-trvleobpA sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirus Infection with Middle East respiratory syndrome coronavirus Calling for rapid development of a safe and effective MERS vaccine Prevalence of antibodies against rubella virus in The Netherlands 9 years after changing from selective to mass vaccination Antibodies against mumps in The Netherlands as assessed by indirect ELISA and virus neutralization assay Comparison of a neutralization enzyme- immunoassay and an enzyme- linked- immunosorbent- assay for evaluation of immune status of children vaccinated for mumps Measles, rubella, mumps, and varicella seroprevalence among health care workers in Turkey: is prevaccination screening cost- effective?
cord-313684-61hkogdhWhy Children Fare Better than Adults?
cord-307811-6e3j0pn7Tissue specific distribution of sulfated mucopolysaccharides in mammals Bio- specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion Heparan sulfates and heparins: similar compounds performing the same functions in vertebrates and invertebrates?
cord-307811-6e3j0pn7Would a rose by another name smell as sweet?
cord-262673-j2ot35ltDo men have a higher case fatality rate of severe acute respiratory syndrome than women do?
cord-262673-j2ot35ltH1N1 influenza in the United States Severe morbidity and mortality associated with respiratory syncytial virus versus influenza infection in hospitalized older adults Respiratory syncytial virus infection in elderly and high- risk adults Clinical characteristics and outcomes of human rhinovirus positivity in hospitalized children Detection of human rhinoviruses in the lower respiratory tract of lung transplant recipients Upper and lower respiratory tract infections by human enterovirus and rhinovirus in adult patients with hematological malignancies Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocytederived macrophages and dendritic cells Macrophages: a Trojan horse in COVID-19?
cord-262673-j2ot35ltHow the SARS coronavirus causes disease: host or organism?
cord-262673-j2ot35ltMiddle East respiratory syndrome coronavirus( MERS- CoV) causes transient lower respiratory tract infection in rhesus macaques Clinical features and viral diagnosis of two cases of infection with Middle East respiratory syndrome coronavirus: a report of nosocomial transmission SARS- CoV2: should inhibitors of the renin- angiotensin system be withdrawn in patients with COVID-19?
cord-262673-j2ot35ltSpatiotemporal interplay of severe acute respiratory syndrome coronavirus and respiratory mucosal cells drives viral dissemination in rhesus macaques Location or origin?
cord-262673-j2ot35ltThe involvement of natural killer cells in the pathogenesis of severe acute respiratory syndrome Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome SARS- CoV-2 infection in children: transmission dynamics and clinical characteristics Will children reveal their secret?
cord-262673-j2ot35ltThe role of neutrophil extracellular traps in Covid-19: only an hypothesis or a potential new field of research?
cord-262673-j2ot35ltWhat is critical for macrophage propagation of lung fibrosis?
cord-295433-olmein3qA comparison of bats and rodents as reservoirs of zoonotic viruses: Are bats special?
cord-295433-olmein3qBats and zoonotic viruses: Can we confidently link bats with emerging deadly viruses?
cord-295433-olmein3qFurther Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus Middle East respiratory syndrome( MERS): Bats or dromedary, which of them is responsible?
cord-295433-olmein3qHow do these viruses modulate the numerous host responses in bats and how does that affect virus replication?
cord-312533-4u3bmb0e2009 H1N1 strain Should remaining stockpiles of smallpox virus( variola) be destroyed?
cord-312533-4u3bmb0eDo men have a higher case fatality rate of severe acute respiratory syndrome than women do?
cord-309898-sju15hevRecent insights into emerging coronaviruses Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia MERS in South Korea and China: A potential outbreak threat?
cord-309898-sju15hevSARS- CoV-2 Have Arisen via Serial Passage through an Animal Host or Cell Culture?:
cord-304227-rbr2un1uWhat are the implications for public health practice?
cord-304227-rbr2un1uWhat is added by this report?
cord-304227-rbr2un1uWhat is already known on this topic?
cord-318872-0e5zjaz1, Saudi Arabia Descriptive epidemiology and characteristics of confirmed cases of Middle East respiratory syndrome coronavirus infection in the Makkah Region of Saudi Arabia MERS- CoV outbreak in Jeddah- a link to health care facilities Estimating the severity and subclinical burden of Middle East respiratory syndrome coronavirus infection in the Kingdom of Saudi Arabia Predictors of MERS- CoV infection: a large case control study of patients presenting with ILI at a MERS- CoV referral hospital in Saudi Arabia Taking stock of the first 133 MERS coronavirus cases globally- is the epidemic changing?
cord-318585-cp76qr9fWorld Health Organization Clinical and laboratory findings of the first imported case of Middle East respiratory syndrome coronavirus( MERS- CoV) into the United States First cases of middle east respiratory syndrome coronavirus( MERS- COV) infections in France, investigations and implications for the prevention of human- to- human transmission Case fatality: rate, ratio, or risk?
cord-318954-pj5lsvsaConvalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Hyperimmune IV immunoglobulin treatment: a multicenter double- blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection Successful treatment of avian influenza with convalescent plasma Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-298350-pq1dcz3aA coincidence?
cord-298350-pq1dcz3aCould it have been due to an intentional act?
cord-298350-pq1dcz3aIs this indicative of how all new emerging disease threats will be handled?
cord-298350-pq1dcz3a• Is coronavirus just a relic?
cord-308061-hz7fsn2gA key question is whether we can use upper- respiratory- tract samples for RT- PCR- based diagnostics?
cord-308061-hz7fsn2gg authors: Drosten, Christian title: Is MERS another SARS?
cord-287953-prn8cnvo-what is the evidence?
cord-287953-prn8cnvoAre hygiene standards useful in assessing infection risk?
cord-287953-prn8cnvoOne Man, Many South Korean Hospitals[ WWW Document Epidemiological Investigation on the 119th Confirmed MERS- CoV Case with the Indefinite Mode of Transmission in Pyeongtaek Outbreak Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study A dynamic model of the systemic causes for patient treatment delays in emergency departments How do we assess hospital cleaning?
cord-287953-prn8cnvoThe diagnosis of healthcare policy problems in Korea Historical and changing epidemiology of healthcare- associated infections Evidence- based model for hand transmission during patient care and the role of improved practices Transmission of viruses via contact in a household setting: experiments using bacteriophage??
cord-287953-prn8cnvoThe diagnosis of healthcare policy problems in Korea Historical and changing epidemiology of healthcare- associated infections Evidence- based model for hand transmission during patient care and the role of improved practices Transmission of viruses via contact in a household setting: experiments using bacteriophage??
cord-293127-c27qh5y7, it is necessary to think forwards towards a resumption of services and a number of questions need to be answered around the management of ART: Should we cancel all ART cycles at this moment?
cord-293127-c27qh5y7A novel coronavirus associated with severe acute respiratory syndrome Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus- Infected Pneumonia Novel corona virus disease( COVID-19) in pregnancy: What clinical recommendations to follow?
cord-293127-c27qh5y7Should we keep only embryo transfers for couple whose success of treatment can be impaired or those who desire transfer the embryos?
cord-293127-c27qh5y7Should we keep the treatments and postpone all embryo transfers?
cord-293127-c27qh5y7à Saúde A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person- to- person transmission: a study of a family cluster Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus( COVID-19) infection Identification of a novel coronavirus in patients with severe acute respiratory syndrome Perinatal Transmission of COVID-19 Associated SARS- CoV-2: Should We Worry?
cord-301547-d4wt9dqp, Saudi Arabia Are Saudi medical students aware of middle east respiratory syndrome coronavirus during an outbreak?
cord-301547-d4wt9dqpAmong Korean Adults: Do Women Have a Higher Level of Health Literacy Than Men?
cord-301547-d4wt9dqpIs the Saudi public aware of Middle East respiratory syndrome?
cord-301547-d4wt9dqpWon S- y, Pascall G. A Confucian War over Childcare?
cord-320921-eumuid3rMiddle East respiratory syndrome coronavirus experimental transmission using a pig model Risk factors for transmission of Middle East respiratory syndrome coronavirus infection during the 2015 outbreak in South Korea Impact of prior seasonal H3N2 influenza vaccination or infection on protection and transmission of emerging variants of influenza A(H3N2)v virus in ferrets Efficacy of seasonal live attenuated influenza vaccine against virus replication and transmission of a pandemic 2009 H1N1 virus in ferrets Predicting"airborne"influenza viruses:( trans-) mission impossible?
cord-303917-2tu707ngChloroquine is a potent inhibitor of SARS coronavirus infection and spread Membrane- related effects underlying the biological activity of the anthraquinones emodin and barbaloin Emodin blocks the SARS coronavirus spike protein and angiotensin- converting enzyme 2 interaction Old drugs as lead compounds for a new disease?
cord-303917-2tu707ngDo men have a higher case fatality rate of severe acute respiratory syndrome than women do?
cord-303917-2tu707ngPotent neutralization of severe acute respiratory syndrome( SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-303917-2tu707nginduce robust and multifunctional T cell responses against both viruses in an appropriate mouse model Measles- derived vaccines to prevent emerging viral diseases Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets Convalescent plasma: new evidence for an old therapeutic tool?
cord-317435-4yuw7jo3Putting the patient back together- social medicine, network medicine, and the limits of reductionism The$ 2.6 billion pill- methodologic and policy considerations silico oncology drug repositioning and polypharmacology Individualized network- based drug repositioning infrastructure for precision oncology in the panomics era Drug repurposing: new treatments for Zika virus infection?
cord-317435-4yuw7jo3its possible role in the management of viral infections- a brief review Melatonin in bacterial and viral infections with focus on sepsis: a review Ebola virus disease: potential use of melatonin as a treatment One molecule, many derivatives: a never- ending interaction of melatonin with reactive oxygen and nitrogen species?
cord-312434-yx24golq: what can they teach us about the severe acute respiratory syndrome?
cord-312434-yx24golqand now the 2019-novel CoV: have we investigated enough about coronaviruses?
cord-312434-yx24golqwhat lessons have we learned?
cord-267540-9p4rky4c6 Exportation is being closely watched, but might the virus find another niche environment where it can successfully establish sustained transmission?
cord-267540-9p4rky4cHow long will this surveillance be needed?
cord-267540-9p4rky4cHow will the situation evolve?
cord-267540-9p4rky4cIs this because of the absence of importation or to surveillance systems in these countries?
cord-267540-9p4rky4cLaboratory testing for middle east respiratory syndrome coronavirus interim recommendations( revised Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-267540-9p4rky4cWhat is happening with MERS CoV transmission in countries with high likelihood of importation?
cord-267540-9p4rky4cWill it spread far and wide, immediately or after a delay?
cord-267540-9p4rky4cWill the current state of geographically limited transmission persist indefinitely?
cord-267540-9p4rky4cWill the disease be extinguished at its source?
cord-286683-mettlmhz: what decides the outcome?
cord-286683-mettlmhzCould enhanced influenza and pneumococcal vaccination programs help limit the potential damage from SARS- CoV-2 to fragile health systems of southern hemisphere countries this winter?
cord-286683-mettlmhzISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals Pediatric Patients With 2019 Coronavirus Disease in China Characteristics of pediatric SARS- CoV-2 infection and potential evidence for persistent fecal viral shedding Angiotensin- converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults Are children less susceptible to COVID-19?
cord-286683-mettlmhzIf clinically indicated:"Is it?
cord-286683-mettlmhzReport of two cases& review of the literature Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical manifestations and outcome of SARS- CoV-2 infection during pregnancy Coronavirus in pregnancy and delivery: rapid review Coronavirus Disease 2019( COVID-19) and Pregnancy: What obstetricians need to know Guidelines for pregnant women with suspected SARS- CoV-2 infection Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province Novel corona virus disease( COVID-19) in pregnancy: What clinical recommendations to follow?
cord-286683-mettlmhzThe convalescent sera option for containing COVID-19 Drugmaker Takeda Is Working on Coronavirus Drug Breadth of concomitant immune responses prior to patient recovery: a case report of non- severe COVID-19 A Tale of Two Viruses: Does Heterologous Flavivirus Immunity Enhance Zika Disease?
cord-286683-mettlmhzThe role of ultrasound lung artifacts in the diagnosis of respiratory diseases Is there a role for lung ultrasound during the COVID-19 pandemic?
cord-319501-a2x1hvkkThe action points at which viral proteins function marked with a question mark(?) represent controversial and inconclusive findings in the field or molecular mechanisms not well studied.
cord-319501-a2x1hvkkannouncement of the coronavirus study group Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control Inhibition of novel β coronavirus replication by a combination of interferon- α2b and ribavirin Distinct immune response in two MERS- CoV- infected patients: Can we go from bench to bedside?
cord-326864-i1r3bv4pThe COVID-19 vaccine development landscape Can Chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-009594-0rfbmi0qVery soon after arrival, Joe arrived on my doorstep, announced who he was, checked who I was and asked why the[ expletive] was I sitting up reading a book when there was vet work to be done?
cord-009594-0rfbmi0qCan we better articulate a more robust and satisfying basis for the AVA's policy and advocacy work on animal welfare issues?
cord-009594-0rfbmi0qCan you join the leadership crew and help to steer the profession?
cord-009594-0rfbmi0qHow do we reflect your views and represent you to stakeholders and politicians?
cord-009594-0rfbmi0qIs there a common thread or philosophy on animal welfare across all members?
cord-009594-0rfbmi0qNot involved with cows, horses, small animals or practice management?
cord-009594-0rfbmi0qPerhaps all of these?
cord-009594-0rfbmi0qShould AVA hold a conversation- type event?
cord-009594-0rfbmi0qShould we have a stand- alone strategy?
cord-009594-0rfbmi0qShould we have a welfare committee?
cord-009594-0rfbmi0qWhat are the most important ones for our members and the long- term benefits for animals?
cord-009594-0rfbmi0qWhere to on welfare?
cord-256086-8qfeoayb( i) Have the resources invested in strategic and routine communication for past pandemic outbreaks yielded public health preparedness benefits?
cord-256086-8qfeoayb( ii) Have past efforts sensitized people to pay attention to new pandemic threats?
cord-256086-8qfeoaybAmong those who had heard of MERS, what were the sources they used to first learn about it?
cord-256086-8qfeoaybAmong those who have low awareness of pandemics, who are they and what are their background characteristics?
cord-256086-8qfeoaybDid H1N1 influenza prevention messages reach the vulnerable population along the Mississippi Gulf Coast?
cord-256086-8qfeoaybIncidence of Spring and Summer Getting vaccinated or not getting vaccinated?
cord-256086-8qfeoaybIndependent variables † Awareness of previous pandemic outbreaks was assessed by asking the participants:'Have you heard of[ 1] SARS,[ 2] H1N1 or swine flu,[ 3] Bird Flu or Avian Flu( H5N1),[ 4] new bird flu or Influenza A(H7N9) and[ 5] MERS( also called MERS- CoV, Middle East Respiratory Syndrome, Novel coronavirus, or NCoV), in the past 10 years?'
cord-256086-8qfeoaybWhat is already known on this topic?
cord-256086-8qfeoaybWhat this study adds?
cord-256086-8qfeoayba'boy cries wolf'effect, making people less attentive to information provided concerning pandemic outbreaks?
cord-256086-8qfeoaybkey: cord-256086- 8qfeoayb authors: Lin, Leesa; McCloud, Rachel F.; Bigman, Cabral A.; Viswanath, Kasisomayajula title: Tuning in and catching on?
cord-305534-936peb1nA 55-day- old female infant infected with COVID 19: presenting with pneumonia, liver injury, and heart damage Anosmia and dysgeusia in the absence of other respiratory diseases: should COVID-19 infection be considered?
cord-305534-936peb1nSingle- cell RNA- seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease SARS- coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS Acute renal impairment in coronavirus- associated severe acute respiratory syndrome Should COVID-19 Concern Nephrologists?
cord-305534-936peb1nWhy and to what extent?
cord-305534-936peb1nis faecal- oral transmission of SARS- CoV-2 possible?
cord-291916-5yqc3zcxAre they closely related?
cord-291916-5yqc3zcxNew evidence for an old therapeutic tool?
cord-291916-5yqc3zcxThe Allplex 2019-nCoV( Seegene) assay: Which performances are for SARS- CoV-2 infection diagnosis?
cord-291916-5yqc3zcxThe epidemiology and pathogenesis of coronavirus disease( COVID-19) outbreak Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Enteric involvement of coronaviruses: Is faecal- oral transmission of SARS- CoV-2 possible?
cord-291916-5yqc3zcxWhat we know?
cord-291916-5yqc3zcxcyclin G- associated kinase regulate hepatitis C virus entry and are potential drug targets Effects of chloroquine on viral infections: An old drug against today's diseases?
cord-312178-tojgojjf( COVID-19) in Inpatient Obstetric Healthcare Settings COVID-19: faecal- oral transmission?
cord-312178-tojgojjfLactation A Trial of Lopinavir- Ritonavir in Adults Hospitalized with Severe Covid-19 Treating COVID-19-Off- Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics Recommendations for the Use of Antiretroviral Drugs in Pregnant Women with HIV Infection and Interventions to Reduce Perinatal HIV Transmission in the United States Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-312178-tojgojjfShould We Worry?
cord-312178-tojgojjfWhat Is Known?
cord-319784-lpmsaluxA feasibility study across three countries via smartphones Circulation of respiratory viruses among pilgrims during the 2012 Hajj pilgrimage Protective measures against acute respiratory symptoms in French pilgrims participating in the Hajj of Non- pharmaceutical interventions for the prevention of respiratory tract infections during Hajj pilgrimage Incubation periods of acute respiratory viral infections: a systematic review Has Hajj- associated Middle East Respiratory Syndrome Coronavirus transmission occurred?
cord-319784-lpmsaluxAustralian Hajj pilgrims'infection control beliefs and practices: insight with implications for public health approaches Australian Hajj pilgrims'knowledge, attitude and perception about Ebola French Hajj pilgrims'experience with pneumococcal infection and vaccination: a knowledge, attitudes and practice( KAP) evaluation Health knowledge, attitude and practice among Iranian pilgrims Pro- smoking apps for smartphones: the latest vehicle for the tobacco industry?
cord-319784-lpmsaluxThe world's first application of participatory surveillance at a mass gathering: FIFA World Cup Health monitor project Who uses smoking cessation apps?
cord-325261-bdumhy5bThe papain- like protease of avian infectious bronchitis virus has deubiquitinating activity Deubiquitination, a New Function of the Severe Acute Respiratory Syndrome Coronavirus Papain- Like Protease?
cord-325261-bdumhy5bThiopurine Analogue Inhibitors of Severe Acute Respiratory Syndrome- Coronavirus Papain- Like Protease, a Deubiquitinating and deISGylating Enzyme Are Patients with Inflammatory Bowel Disease at Increased Risk for Covid-19 Infection?
cord-328175-4i3cz20jMiddle East respiratory syndrome coronavirus( MERS- CoV) causes transient lower respiratory tract infection in rhesus macaques Transmission of MERS- coronavirus in household contacts Infection with MERS- CoV causes lethal pneumonia in the common marmoset Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits Prophylaxis with a MERS- CoV- specific human monoclonal antibody protects rabbits from MERS- CoV infection Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Potent neutralization of MERS- CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein A humanized neutralizing antibody against MERS- CoV targeting the receptor- binding domain of the spike protein Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS- CoV in vivo Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-328000-i9tzr13zAm I ready for CRISPR?
cord-320909-p93gxjm2: cord-320909-p93gxjm2 authors: Natoli, S.; Oliveira, V.; Calabresi, P.; Maia, L. F.; Pisani, A. title: Does SARS‐Cov‐2 invade the brain?
cord-320909-p93gxjm2Prophylactic and therapeutic remdesivir( GS-5734) treatment in the rhesus macaque model of MERS- CoV infection Guillain- Barr e syndrome associated with SARS- CoV-2 infection: causality or coincidence?
cord-320909-p93gxjm2Viral and cellular factors involved in neuroinvasiveness and neuropathogenesis Multiple organ infection and the pathogenesis of SARS Interaction of severe acute respiratory syndrome- associated coronavirus with dendritic cells Is there an ideal animal model for SARS?
cord-326133-d46wbfrxA comparison of cell and tissue extraction techniques using high- resolution 1H- NMR spectroscopy Simultaneously extracting DNA, RNA, and protein using kits: is sample quantity or quality prejudiced?
cord-330315-upcf15q5Do viruses subvert cholesterol homeostasis to induce host cubic membranes?
cord-312740-2ro2p77q: What lessons have we learned?
cord-312740-2ro2p77qAn in silico study Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-312740-2ro2p77qCOVID-19: What is next for public health?
cord-312740-2ro2p77qThe classification of viruses infecting the respiratory tract Nucleoside/ nucleotide analog inhibitors of hepatitis B virus polymerase: Mechanism of action and resistance Drug repurposing for viral infectious diseases: How far are we?
cord-323428-jd91k19z: Can we go from bench to bedside?
cord-323428-jd91k19zEmergence of a novel human coronavirus Middle East respiratory syndrome coronavirus"MERS- CoV": Current knowledge gaps Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans MERS- CoV-- are we on the verge of a pandemic?
cord-312741-0au4ncttA decade after SARS: strategies for controlling emerging coronaviruses SARS vaccines: where are we?
cord-312741-0au4ncttIn vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Inhibition of human coronavirus 229E infection in human epithelial lung cells( L132) by chloroquine: involvement of p38 MAPK and ERK A systematic screen of FDA- approved drugs for inhibitors of biological threat agents Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-312741-0au4ncttThe mercurial nature of neutrophils: still an enigma in ARDS?
cord-312741-0au4ncttthe beginning of another SARS- like pandemic?
cord-332952-d5l60cgcWhy did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-333882-zrdsr3nhThe use of convalescent plasma to treat emerging infectious diseases: focus on Ebola virus disease Immune plasma for the treatment of severe influenza: an open- label, multicentre, phase 2 randomised study Species- specific chromosome engineering greatly improves fully human polyclonal antibody production profile in cattle Molecular basis of binding between novel human coronavirus MERS- CoV and its receptor CD26 Evaluation of candidate vaccine approaches for MERS- CoV Viral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS- CoV in vivo Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-333738-3xtb8gyeThis similarity opens the question whether infection with one coronavirus will confer resistance to other coronaviruses?
cord-324978-9qfhsj3nDid MERS- CoV truly emerge as a human pathogen in 2012, or were cases of cryptic infection not appreciated because of a lack of suitable diagnostic tests?
cord-324978-9qfhsj3nWhat are the roles of bats, if any, as reservoirs of MERS- CoV?
cord-331558-6rqd3fmjThe epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases( COVID-19) in China COVID-19) Situation Report-35 What to do next to control the 2019-nCoV epidemic?
cord-332268-x30svp5yIs lithium a potential treatment for the novel Wuhan( 2019-nCoV) coronavirus?
cord-328835-r9znjkfoSituation report-14 Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome Middle East respiratory syndrome coronavirus( MERS- CoV) infection during pregnancy: report of two cases& review of the literature China coronavirus: what do we know so far?
cord-328835-r9znjkfokey: cord-328835-r9znjkfo authors: Favre, Guillaume; Pomar, Léo; Musso, Didier; Baud, David title: 2019-nCoV epidemic: what about pregnancies?
cord-331022-tek4u751Can We Benefit from the SARS- CoV and MERS- CoV Pandemic Experience?
cord-320928-flsaa1wxWhat is MERS- CoV, and what should I do?:
cord-320928-flsaa1wxWhat's your strategy for managing knowledge?
cord-320928-flsaa1wxjournal article Does perception of knowledge sharing, transfer and recognition have an impact on job satisfaction?
cord-337835-78i6j11iEvidence of person- to- person transmission within a family cluster of novel coronavirus infections An adult returned traveler from Dubai hospitalized with an influenza- like illness( ILI): Middle East Respiratory Syndrome( MERS) or influenza?
cord-326851-0jxdnm1l: What could the West Learn from Asia?
cord-326851-0jxdnm1lWhat Is a Pandemic?
cord-324324-8ybfiz8fCould have the current COVID-19 outbreak been avoided?
cord-324324-8ybfiz8fWhat should we expect from the current pandemic?
cord-330583-ltkpt80uFocus on the Marine Environmental Damage by Oil Pollution in South Korea and Japan Management of Emergent Networks during Disasters- A Meta synthesis Relationship between Effectiveness of Disaster Management and Cooperative Factors of Agencies in Disaster Management MERS Isolation Patient- A Public Enemy?
cord-330583-ltkpt80uHow did MERS Outbreak Become a Political Matter?:
cord-338538-uea9kwgeA structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine Bioengineering bacterial outer membrane vesicles as vaccine platform Bacterial outer membrane vesicles: New insights and applications Meningococcal serogroup B vaccines: Will they live up to expectations?
cord-322760-tsxniu3jSouth Korea Middle East respiratory syndrome coronavirus infections in health care workers Middle East respiratory syndrome coronavirus infection control: the missing piece?
cord-322760-tsxniu3jThe results showed a statistical difference in the distribution of the 0- 14, 15- 29, 30- 44, 45- 59, and 60? year- olds between the two groups( p= 0.000).
cord-294800-akr4f5p8: what's next?
cord-294800-akr4f5p8Can Chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-294800-akr4f5p8Teicoplanin: an alternative drug for the treatment of COVID-19?
cord-294800-akr4f5p8The FDA- approved drug ivermectin inhibits the replication of SARS- CoV-2 in vitro Nuclear trafficking of proteins from RNA viruses: potential target for antivirals?
cord-294800-akr4f5p8The mercurial nature of neutrophils: still an enigma in ARDS?
cord-294800-akr4f5p8a retrospective cohort study Characterization of SARS- CoV- specific memory T cells from recovered individuals 4 years after infection Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-294800-akr4f5p8emergence and implications for emergency care Enteric involvement of coronaviruses: is faecal- oral transmission of SARS- CoV-2 possible?
cord-321918-9jwma2y6Human monoclonal antibodies block the binding of SARS- CoV-2 spike protein to angiotensin converting enzyme 2 receptor A human monoclonal antibody blocking SARS- CoV-2 infection Rapid selection of a human monoclonal antibody that potently neutralizes SARS- CoV-2 in two animal models Therapeutic potential of small molecules and engineered proteins What are the drugs of the future?
cord-321918-9jwma2y6Prim Care Meta- analysis: convalescent blood products for spanish influenza pneumonia: a future h5n1 treatment?
cord-321918-9jwma2y6Targeting membrane- bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the Middle East respiratory syndrome virus Angiotensin- converting enzyme 2: cardioprotective player in the renin- angiotensin system?
cord-339146-ifdgl2bjThe large 386-nt deletion in SARS- associated coronavirus: Evidence for quasispecies?
cord-286298-pn9nwl64: What is the role of radiologists?
cord-286298-pn9nwl64Are aerosol, saliva, feces, urine, and foodborne the only routes of transmission?
cord-286298-pn9nwl64Can Chinese medicine be used for prevention of corona virus disease 2019( COVID-19)?
cord-286298-pn9nwl64Could Intravenous Immunoglobulin Collected from Recovered Coronavirus Patients Protect against COVID-19 and Strengthen the Immune System of New Patients?
cord-286298-pn9nwl64These unresolved questions include: What is the origin of SARS- CoV-2?
cord-286298-pn9nwl64What are the other unknown routes of transmission?
cord-286298-pn9nwl64What is the intermediate host that transmitted the virus from bats?
cord-286298-pn9nwl64Why does the virus cause severe disease and mortality in the elderly or those with co- morbidities, while it is milder in children?
cord-286298-pn9nwl64interferon signals in lung stromal cells protect from influenza virus infection Rescue fecal microbiota transplantation for antibiotic- associated diarrhea in critically ill patients Long- Term safety and efficacy of fecal microbiota transplant in active ulcerative colitis Microbiota and its role on viral evasion: Is it with us or against us?
cord-303941-3lg1bzsiHow long can bats harbor these viruses?
cord-303941-3lg1bzsiHow long can viruses excreted by bats survive in the environment?
cord-303941-3lg1bzsiThere are many questions that remain to be answered about the ecology of bat- borne infections:( 1) Are bats the natural reservoirs or just transient carriers of these novel viruses?
cord-303941-3lg1bzsiWhat are the routes of virus shedding?
cord-303941-3lg1bzsiWhat links bats to emerging infectious diseases?
cord-303941-3lg1bzsiand What are the risk factors leading to infection of humans or intermediate animals exposed to bat- borne viruses?
cord-336150-l8w7xk0bhospitalists'perspective Broad- spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Coronavirus: epidemiology, genome replication and the interactions with their hosts Characterization of the receptorbinding domain( RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine Differential stepwise evolution of SARS coronavirus functional proteins in different host species Dexamethasone for COVID-19?
cord-339386-sxyeuiw1The adaptation of two human coronavirus strains( OC38 and OC43) to growth in cell monolayers Detection of the new human coronavirus HKU1: a report of 6 cases Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures Pleomorphic virus- like particles in human faeces Chronic enterocyte infection with coronavirus: one possible cause of the syndrome of tropical sprue?
cord-342144-awtiqxx5Are 1- 2 dangerous?
cord-334628-axon4jdc: can we confidently link bats with emerging deadly viruses?
cord-334628-axon4jdc: what can they teach us about the severe acute respiratory syndrome?
cord-309089-ex9nh1yiThe mercurial nature of neutrophils: still an enigma in ARDS?
cord-309089-ex9nh1yiWhat does the peripheral blood tell you in SARS?
cord-309089-ex9nh1yia meta- analysis Interleukin-6 as a potential biomarker of COVID-19 progression Inhibition of NF- κB- mediated inflammation in severe acute respiratory syndrome coronavirus- infected mice increases survival Role of chemokines in thyroid cancermicroenvironment: is CXCL8 the main player?
cord-309089-ex9nh1yiantagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/ Golgi membrane Severe acute respiratory syndrome coronavirus open reading frame( ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists One nucleotide in a kappaB site can determine cofactor specificity for NF- kappaB dimers Infection of cultured intestinal epithelial cells with severe acute respiratory syndrome coronavirus SARS coronavirus and innate immunity Inhibition of cytokine gene expression and induction of chemokine genes in nonlymphatic cells infected with SARS coronavirus Activation of AP-1 signal transduction pathway by SARS coronavirus nucleocapsid protein Clinical Progression and Cytokine Profiles of Middle East Respiratory Syndrome Coronavirus Infection Distinct immune response in two MERS- CoVinfected patients: can we go from bench to bedside?
cord-309089-ex9nh1yido you draw the line?
cord-339724-roj8ksvcthe beginning of another SARS- like pandemic?
cord-339762-lh8czr0aDo corticosteroids reduce the mortality of influenza A( H1N1) infection?
cord-338980-pygykil7With inserts and changing structural dynamics between clades or viruses, the questions become 1) which sequence motif are displayed and 2) to what extent are these sequence motifs displayed?
cord-319877-izn315hbDistinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-319877-izn315hbNidovirus transcription: how to make sense …?
cord-319877-izn315hbThe mercurial nature of neutrophils: still an enigma in ARDS?
cord-319877-izn315hbThe role of C5a in acute lung injury induced by highly pathogenic viral infections Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus A decade after SARS: strategies for controlling emerging coronaviruses SARS vaccines: where are we?
cord-321851-ku4z34luDistinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-321851-ku4z34luShould lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season?
cord-321851-ku4z34lua predominant role of histones Is IL-1 a good therapeutic target in the treatment of arthritis?
cord-343789-6tq0kcfdTaking stock of the first 133 MERS coronavirus cases globally- is the epidemic changing?
cord-302983-3v5bc80zA Cross- sectional Survey on COVID-19 Is Pakistan prepared for the COVID-19 epidemic?
cord-302983-3v5bc80zCan we contain the COVID-19 outbreak with the same measures as for SARS?
cord-302983-3v5bc80zThe effects of social determinants on public health emergency preparedness mediated by health communication: The 2015 mers outbreak in south korea Preventive behaviors by the level of perceived infection sensitivity during the Korea outbreak of Middle East Respiratory Syndrome in 2015 Tuning in and catching on?
cord-302983-3v5bc80zThe epidemic and the challenges COVID-19 and Italy: what next?
cord-302983-3v5bc80zThe prevalence of limited health literacy Health literacy and infectious diseases: why does it matter?
cord-302983-3v5bc80zTo what extent are Arab pilgrims to Makkah aware of the middle east respiratory syndrome coronavirus and the precautions against it?
cord-302983-3v5bc80zTo what extent are Arab pilgrims to Makkah aware of the middle east respiratory syndrome coronavirus and the precautions against it?
cord-319707-j8y9gt2oGuillain- Barré syndrome associated with SARS- CoV-2 infection: causality or coincidence?
cord-319707-j8y9gt2oWhat does this mean in the clinical setting?
cord-319707-j8y9gt2oWhat it comes down to?
cord-337089-ksh62ni0Probable pangolin origin of SARS- CoV-2 associated with the COVID-19 outbreak Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross- species transmission from snake to human A novel bat coronavirus closely related to SARS- CoV-2 contains natural insertions at the S1/ S2 cleavage site of the spike protein Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade- long structural studies of SARS coronavirus Genomic characterization of a novel SARS- CoV-2 Clinical manifestations and outcome of SARS- CoV-2 infection during pregnancy Do pets protect their owners in the COVID-19 era?
cord-337089-ksh62ni0a comparative serological study Antibodies against MERS coronavirus in dromedary camels Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe Bats may be SARS reservoir Infection and rapid transmission of SARS- CoV-2 in ferrets COVID-19, SARS and MERS: are they closely related?
cord-335567-ssnvr6njDual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients Clinical impact and diagnosis of human metapneumovirus infection Emerging respiratory agents: New viruses for old diseases?
cord-335567-ssnvr6njPassenger or pathogen in acute respiratory tract infections?
cord-327867-1wkbjtji( 1) what is the underlying growth or trend of the globally reported MERS- CoV cases?
cord-327867-1wkbjtjiWhat are the contributions of various risk factors for MERS- CoV cases?
cord-327867-1wkbjtjiand how do they affect the series?
cord-345046-str19r9a: can we go from bench to bedside?
cord-320548-oigyut2kA( H1N1) virus infection in hospitalized adults: how do they diff er from those in seasonal infl uenza?
cord-320548-oigyut2kDistinct immune response in two MERS- CoV- infected patients: can we go from bench to bedside?
cord-320548-oigyut2kThe frequency of Pneumocystis jirovecii in sputum samples of HIV and TB patients received at the Central Reference Laboratory in Windhoek, Namibia Global burden of chronic pulmonary aspergillosis as a sequel to pulmonary tuberculosis Voriconazole resistance in Aspergillus fumigatus- should we be concerned?
cord-320548-oigyut2kTreating B- cell cancer with T cells expressing anti- CD19 chimeric antigen receptors Cytotoxic therapy for severe swine fl u A/ H1N1 Emergence of multiply resistant pneumococci Molecular characterization of Streptococcus pneumoniae invasive serotype 19A isolates from adults in two Spanish regions Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1- 4 Streptococcus pneumoniae: does antimicrobial resistance matter?
cord-291679-jfxqipt8No alternatives?
cord-291679-jfxqipt8Taking stock of the first 133 MERS coronavirus cases globally- Is the epidemic changing?
cord-291679-jfxqipt8The adequacy of response rates to online and paper surveys: what can be done?
cord-291679-jfxqipt8The case for a'deficit model'of science communication SARS wars: an examination of the quantity and construction of health information in the news media Knowledge and risk perception among nuclearpower- plant employees Why do people sacrifice for their nations?
cord-291679-jfxqipt8The overreaction section comprised the following 2 questions:( 1) How would you react if you realized your children were in the same class as those of someone suspected( or confirmed) to have MERS( including school and extracurricular activities)?; and( 2) How would you react if you realized your children were in the same class as those of medical workers at hospitals with MERS patients( including school and extracurricular activities)?
cord-291679-jfxqipt8The overreaction section comprised the following 2 questions:( 1) How would you react if you realized your children were in the same class as those of someone suspected( or confirmed) to have MERS( including school and extracurricular activities)?; and( 2) How would you react if you realized your children were in the same class as those of medical workers at hospitals with MERS patients( including school and extracurricular activities)?
cord-291679-jfxqipt8The relationship between perceived media dependency, use of alternative information sources, and general trust in mass media Public trust in government in japan and south korea: does the rise of critical citizensmatter?
cord-291679-jfxqipt8What does the public know about Ebola?
cord-291679-jfxqipt8When can categorical variables be treated as continuous?
cord-305134-s7h6bpof: retrospective analysis Is MERS another SARS?
cord-305134-s7h6bpofComplement as a target in COVID-19?
cord-305134-s7h6bpofThe intrinsic pathway of coagulation: a target for treating thromboembolic disease?
cord-305134-s7h6bpofUsing Clinical- Grade Soluble Human ACE2 Endothelial cell infection and endotheliitis in COVID-19 Overcoming barriers: the endothelium as a linchpin of coronavirus disease 2019 pathogenesis?
cord-305134-s7h6bpofWill complement inhibition be the new target in treating COVID-19-related systemic thrombosis?
cord-305134-s7h6bpofa multicenter prospective cohort study Incidence of venous thromboembolism in hospitalized patients with COVID-19 COVID and coagulation: bleeding and thrombotic manifestations of SARS- CoV2 infection Pulmonary embolism or pulmonary thrombosis in COVID-19?
cord-305134-s7h6bpofis the recommendation to use high- dose heparin for thromboprophylaxis justified?
cord-346502-x2b0ao3qWhat are the possible explanations for lack of clinical and virological benefit?
cord-343302-g9vcchrhthe beginning of another SARSlike pandemic?
cord-349661-ppw80s0lHow would Australian hospital staff react to an avian influenza admission, or an influenza pandemic?
cord-346320-ysgz6adrHyperimmune IV immunoglobulin treatment: a multicenter double- blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection SARS: systematic review of treatment effects Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-347587-auook38yMolecular evolution of MERS coronavirus: dromedaries as a recent intermediate host or longtime animal reservoir?
cord-345081-15s2i6f0The atraumatic restorative treatment( ART) technique: does it have a place in everyday practice?
cord-344246-sf9cymhcA report based on 116 cases Analysis of pregnancy outcomes of pregnant women during the epidemic of new coronavirus pneumonia in Hubei Clinical course of severe and critical COVID-19 in hospitalized pregnancies: a US cohort study Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia Possible vertical transmission of SARS- CoV-2 from an infected mother to her newborn Perinatal transmission of COVID-19 associated SARS- CoV-2: should we worry?
cord-344246-sf9cymhcWhat are the risks of COVID-19 infection in pregnant women?
cord-348821-2u6ki9dvOttawa Hospital Research Institute Is diabetes mellitus an independent risk factor for colon cancer and rectal cancer?
cord-342691-8jcfzexyDoes vitamin D status impact mortality from SARS- CoV-2 infection?
cord-342691-8jcfzexyThe critical role of Notch ligand Delta- like 1 in the pathogenesis of influenza A virus( H1N1) infection COVID-19 in the heart and the lungs: could we'Notch'the inflammatory storm?
cord-349781-l93978vqVirology Measles virus suppresses cell- mediated immunity by interfering with the survival and functions of dendritic and T cells Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-344217-kci4uw7uCoronaviruses of man Discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus Occurrence and frequency of coronavirus infections in humans as determined by enzyme- linked immunosorbent assay Human coronaviruses: what do they cause?
cord-344217-kci4uw7uEmerg Infect Dis Wet markets- a continuing source of severe acute respiratory syndrome and influenza?
cord-321259-wio2b49iAltogether, further clinical work must clarify if chloroquine and hydroxychloroquine have major effects on COVID-19 and at which( early?)
cord-321259-wio2b49iAssociated with the Severe Acute Respiratory Syndrome Coronavirus Replication Complex Rapamycin- induced autophagy restricts porcine epidemic diarrhea virus infectivity in porcine intestinal epithelial cells Autophagy and viruses: adversaries or allies?
cord-321259-wio2b49iCan autophagy induction reduce cellular infection, and does the virus actively inhibit autophagy( suggesting antiviral effects for autophagy)?
cord-321259-wio2b49iChloroquine is a potent inhibitor of SARS coronavirus infection and spread Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non- randomized clinical trial Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus( 2019-nCoV) in vitro Regulators split on antimalarials for COVID-19 Chloroquine and hydroxychloroquine in covid-19 Should chloroquine and hydroxychloroquine be used to treat COVID-19?
cord-321259-wio2b49iNevertheless, the diverse putative roles of autophagy during viral infection[ 38] require that two opposite aspects be covered by this overview:( i) Is there evidence for autophagy being used for the survival or replication of CoVs( proviral effects)?
cord-349010-n4s8dzgpThe multifunctional or moonlighting protein CD26/ DPPIV Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-333144-gyuh2fvlAn alternative drug for the treatment of COVID-19?
cord-333144-gyuh2fvlAnother zoonotic betacoronavirus causing SARS- like disease Efficacy of hydroxychloroquine in patients with COVID-19: Results of a randomized clinical trial Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: Trends, scope and relevance Doxycycline, a widely used antibiotic in dermatology with a possible anti- inflammatory action against IL-6 in COVID-19 outbreak MERS- CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte- derived antigen- presenting cells Favipiravir, an antiviral for COVID-19?
cord-333144-gyuh2fvlThe COVID-19 vaccine development landscape Dexamethasone for COVID-19?
cord-333144-gyuh2fvlWhat is new on its pathogenesis and complications?
cord-354536-c9v9kbw8The Ebola epidemic crystallizes the potential of passive antibody therapy for infectious diseases Selection of Vaccinia Virus- Neutralizing Antibody from a Phage- Display Human- Antibody Library Screening of FDA- approved drugs using a MERS- CoV clinical isolate from South Korea identifies potential therapeutic options for Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates Enhancement of infectivity of a non- syncytium inducing HIV-1 by sCD4 and by human antibodies that neutralize syncytium inducing HIV-1 Convalescent plasma: new evidence for an old therapeutic tool?
cord-324671-7xdnmms9Participants also answered the following questions about their exposure to MERS:"Have you been within 2 meters of a MERS patient while not wearing personal protective equipment( PPE)?,""Have you treated MERS patients in person while wearing PPE?,""Have you experiences MERS- like symptoms after contact with MERS patients?,""Have you ever been quarantined?,""Have your hospital or employees been exposed to media reports about the MERS outbreak, such as TV, internet, radio and so on?.
cord-324671-7xdnmms9Participants also answered the following questions about their exposure to MERS:"Have you been within 2 meters of a MERS patient while not wearing personal protective equipment( PPE)?,""Have you treated MERS patients in person while wearing PPE?,""Have you experiences MERS- like symptoms after contact with MERS patients?,""Have you ever been quarantined?,""Have your hospital or employees been exposed to media reports about the MERS outbreak, such as TV, internet, radio and so on?.
cord-324671-7xdnmms9Participants also answered the following questions about their exposure to MERS:"Have you been within 2 meters of a MERS patient while not wearing personal protective equipment( PPE)?,""Have you treated MERS patients in person while wearing PPE?,""Have you experiences MERS- like symptoms after contact with MERS patients?,""Have you ever been quarantined?,""Have your hospital or employees been exposed to media reports about the MERS outbreak, such as TV, internet, radio and so on?.
cord-324671-7xdnmms9Participants also answered the following questions about their exposure to MERS:"Have you been within 2 meters of a MERS patient while not wearing personal protective equipment( PPE)?,""Have you treated MERS patients in person while wearing PPE?,""Have you experiences MERS- like symptoms after contact with MERS patients?,""Have you ever been quarantined?,""Have your hospital or employees been exposed to media reports about the MERS outbreak, such as TV, internet, radio and so on?.
cord-324671-7xdnmms9Participants also answered the following questions about their exposure to MERS:"Have you been within 2 meters of a MERS patient while not wearing personal protective equipment( PPE)?,""Have you treated MERS patients in person while wearing PPE?,""Have you experiences MERS- like symptoms after contact with MERS patients?,""Have you ever been quarantined?,""Have your hospital or employees been exposed to media reports about the MERS outbreak, such as TV, internet, radio and so on?.
cord-307995-8q7efrqk: what's the risk?
cord-307995-8q7efrqkCan the geographical patterns help locate an animal source?
cord-307995-8q7efrqkHospital outbreak of Middle East respiratory syndrome coronavirus Middle East respiratory syndrome coronavirus infection control: the missing piece?
cord-307995-8q7efrqkIs the virus adapting to humans?
cord-307995-8q7efrqkThe full genome sequences from MERS patients with known dates and locations can help answer these questions: How fast does the virus change?
cord-307995-8q7efrqkWhat are the transmission patterns?
cord-307995-8q7efrqkWhen did the virus begin circulating in its current form?
cord-352492-6ihyiwgb: what is its contribution to blood safety?
cord-354582-fniymnmfThe SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-352527-eeyqh9ncthe beginning of another SARS- like pandemic?
cord-353495-c3s5n5vothe beginning of another SARS- like pandemic?
cord-352322-tsjwnvkkInvestigating the introduction of porcine epidemic diarrhea virus into an Ohio swine operation Molecular analysis of Brazilian strains of bovine coronavirus( BCoV) reveals a deletion within the hypervariable region of the S1 subunit of the spike glycoprotein also found in human coronavirus OC43 New porcine coronavirus?
cord-346331-d0s028wl; Williams, Janet E.; Bode, Lars; Donovan, Sharon M.; Järvinen, Kirsi M.; Seppo, Antti E.; Raiten, Daniel J.; Meehan, Courtney L.; McGuire, Mark A.; McGuire, Michelle K. title: SARS‐CoV‐2 and human milk: What is the evidence?
cord-346331-d0s028wlBorn to Mothers With COVID-19 Pneumonia Postnatal transmission of aids- associated retrovirus from mother to infant SARS- CoV-2 and human milk: What is the evidence?
cord-346331-d0s028wlThe Lancet Cytomegalovirus infection of breast milk and transmission in infancy Perinatal transmission of COVID-19 associated SARS- CoV-2: Should we worry?
cord-289535-srrfr1esCD8+ T- cell responses after rAd5 boost in a randomized clinical trial BCG- induced trained immunity: can it offer protection against COVID-19?
cord-289535-srrfr1esCan existing live vaccines prevent COVID-19?
cord-289535-srrfr1esCould an unrelated live attenuated vaccine serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection?
cord-289535-srrfr1esHow immune T- cell augmentation can help prevent COVID-19: a possible nutritional solution using ketogenic lifestyle jri/ vol4without altering disease transmission work?
cord-289535-srrfr1esHow to achieve equitable global distribution?
cord-289535-srrfr1esIs human challenge part of the pathway to a licensed product?
cord-289535-srrfr1esIs there an ideal animal model for SARS?
cord-289535-srrfr1esMammalian microRNAs predominantly act to decrease target mRNA levels AU- rich elements and associated factors: are there unifying principles?
cord-289535-srrfr1esNonspecific protection of mice against influenza virus infection by local or systemic immunization with bacille Calmette- Guerin Is global BCG vaccination coverage relevant to the progression of SARS- CoV-2 pandemic?
cord-289535-srrfr1esWhat is the risk of immunopathology?
cord-289535-srrfr1esWhy Norwood?
cord-356364-ipi81ce3the beginning of another SARS- like pandemic?
cord-353704-lfndq85xWhy are RNA virus mutation rates so damn high?
cord-336775-d4hi9mykGenomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
cord-336775-d4hi9mykInsights into the structure of the coronavirion Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor Environmental Contamination and Viral Shedding in MERS Patients During MERS- CoV Outbreak in South Korea Emergence of Novel Coronavirus and COVID-19: whether to stay or die out?
cord-336775-d4hi9mykReally'Special'as Viral Reservoirs?
cord-336775-d4hi9mykwhat can they teach us about the severe acute respiratory syndrome?
cord-305745-9lngdjowA review on the phytochemistry, pharmacology, and pharmacokinetics of amentoflavone Flavonoids: promising natural compounds against viral infections Old drugs as lead compounds for a new disease?
cord-305745-9lngdjowBaicalin is also a known inhibitor of HIV-1 reverse transcriptase( Li et al. 2000), and was shown to possess inhibitory potential against influenza in vitro and in vivo by acting as immune modulator promoting IFN- c production in mice and human CD4?
cord-305745-9lngdjowCoronaviruses( CoVs) are highly diverse, enveloped, positive- sense, single- stranded RNA viruses(? ssRNA)
cord-305745-9lngdjowInsights from structures of protease and inhibitors Immunomodulatory effects of flavonoids: possible induction of T CD4?
cord-305745-9lngdjowIsolation of specific cranberry flavonoids for biological activity assessment Š mejkal K Flavonoids as novel efflux pump inhibitors and antimicrobials against both environmental and pathogenic intracellular mycobacterial species Structurally modified'dietary flavonoids': are these viable drug candidates for chemoprevention?
cord-305745-9lngdjowan overview Plant polyphenols as dietary antioxidants in human health and disease Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS- CoV Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors Synthesis and antiviral evaluation of 7-O- arylmethylquercetin derivatives against SARS- associated coronavirus( SCV) and hepatitis C virus( HCV) Rhodiosin and herbacetin in Rhodiola rosea preparations: additional markers for quality control?
cord-305745-9lngdjowand CD8?
cord-305745-9lngdjowtitle: Flavonoids: A complementary approach to conventional therapy of COVID-19?
cord-305745-9lngdjowwhat we know?
cord-342052-v4y1xc90: hospital dissemination and intrafamilial spread Marburg hemorrhagic fever associated with multiple genetic lineages of virus Ebola virus as a foodborne pathogen?
cord-342052-v4y1xc90Hospital outbreak of Middle East respiratory syndrome coronavirus Progress audit of Biosecurity Queensland response activities at Cawarral in Evidence for Camel- to- Human Transmission of MERS coronavirus Is that a rodent in your luggage?
cord-342052-v4y1xc90Hyspignathus monstrosus Search for the Ebola virus reservoir in Kikwit, Democratic Republic of the Congo: reflections on a vertebrate collection Statistical inference in a stochastic epidemic SEIR model with control intervention: Ebola as a case study Fruit bats as reservoirs of Ebola virus Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo Dissemination of Cefotaxime- M- Producing Escherichia coli isolates in poultry farms, but not swine farms, in China Experimental inoculation study indicates swine as a potential host for Hendra virus Foodborne transmission of Nipah virus Proportion of deaths and clinical features in Bundibugyo Ebola virus infection Biosecurity Authority, Ministry of Agriculture and Forestry Is Marburg virus enzootic in Gabon?
cord-342052-v4y1xc90Interferon- beta therapy prolongs survival in Rhesus macaque models of Ebola and Marburg hemorrhagic Fever Qualitative release assessment to estimate the likelihood of Henipavirus entering the United Kingdom MERS in South Korea and China: a potential outbreak threat?
cord-352256-qxdakdk0-α What can we predict about viral evolution and emergence?
cord-352256-qxdakdk0What to expect for COVID-19?
cord-347128-6lyoz8nnMore than meets the eye?
cord-347128-6lyoz8nnNew insights into the antiviral effects of chloroquine New insights on the antiviral effects of chloroquine against coronavirus: What to expect for COVID-19?
cord-347128-6lyoz8nnWhy are Oseltamivir and Zanamivir effective against the newly emerged influenza A virus( A/ H1N1)?
cord-342739-iy9vjpuhA critical question that must be answered at this stage- with a clear view of the potential deleterious effects of a new coronavirus in pregnancy- is will maternal immunization be a priority in research and development?
cord-342739-iy9vjpuhHas modern technology improved maternal and fetal outcome?
cord-342739-iy9vjpuhWhat lessons have we learned?
cord-342739-iy9vjpuhWhen is it acceptable to vaccinate pregnant women?
cord-350925-1h6pbfwp: It May Be Molecular methods used to estimate thermal inactivation of a prototype human norovirus: More heat resistant than previously believed?
cord-350925-1h6pbfwpPossible role of Dewar photoproducts in solar mutagenesis COVID-19, SARS and MERS: are they closely related?
cord-350925-1h6pbfwpThe SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-348278-is20odaqA case of long- term excretion and subclinical infection with middle east respiratory syndrome coronavirus in a healthcare worker Stability of middle east respiratory syndrome coronavirus( MERS- CoV) under different environmental conditions Environmental contamination and viral shedding in MERS patients during MERS- CoV outbreak in South Korea the role of super- spreaders in infectious disease Middle east respiratory syndrome: SARS redux?
cord-348278-is20odaqAn update on middle east respiratory syndrome: 2 years later Middle east respiratory syndrome coronavirus infection control: the missing piece?
cord-348278-is20odaqwhat do we know?
cord-321800-0h28pg3b: Have we investigated enough about coronaviruses?
cord-321800-0h28pg3bA potential tool for studying journals?
cord-321800-0h28pg3bBut the question arises whether this is a short- term effect which, once CoVID-19 is contained, will lead to an equally sharp decline in publication numbers as was observed with the earlier CoV pandemics SARS and MERS?
cord-321800-0h28pg3bBut what about the sense of all these undertakings and what can be learned about the future for a better understanding?
cord-321800-0h28pg3bCan we learn from previous research patterns regarding CoV?
cord-321800-0h28pg3bHow can we use past efforts, their intensification and the influences of research on CoV positively to better understand the needs for sustainable and appropriate research?
cord-321800-0h28pg3bWhat influence do they have on future research?
cord-287758-da11ypiy( COVID-19) Clinically Significant Drug Interactions with Cyclosporin Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/ Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus( MERS- CoV), and Severe Acute Respiratory Syndrome Coronavirus( SARS- CoV) Discovery and development of safe- in- man broadspectrum antiviral agents Teicoplanin: an alternative drug for the treatment of COVID-19?
cord-287758-da11ypiy: cord-287758-da11ypiy authors: Mônica Vitalino de Almeida, Sinara; Cleberson Santos Soares, José; Lima dos Santos, Keriolaine; Emanuel Ferreira Alves, Josival; Galdino Ribeiro, Amélia; Trindade Tenório Jacob, Íris; Juliane da Silva Ferreira, Cindy; Celerino dos Santos, Jéssica; Ferreira de Oliveira, Jamerson; Bezerra de Carvalho Junior, Luiz; do Carmo Alves de Lima, Maria title: COVID-19 therapy: what weapons do we bring into battle?
cord-287758-da11ypiyA Review of Its Use in the Management of HIV-1 Infection Discovering drugs to treat coronavirus disease 2019( COVID-19) Therapeutic Options and Critical Care Strategies in COVID-19 Patients; Where Do We Stand in This Battle?
cord-287758-da11ypiyA new trick for an old drug?
cord-287758-da11ypiyAntiviral treatment of COVID-19 Hydroxychloroquine and ivermectin: A synergistic combination for COVID-19 chemoprophylaxis and treatment?
cord-287758-da11ypiyClinical course and outcomes of critically ill patients with SARS- CoV-2 pneumonia in Wuhan, China: a single- centered, retrospective, observational study Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-287758-da11ypiyEngineering an antiviral for COVID-19?
cord-287758-da11ypiyHow Far Are We?
cord-287758-da11ypiyThe Use of Cyclosporine A in Rheumatology: a 2016 Comprehensive Review Cyclosporine A: a valid candidate to treat COVID-19 patients with acute respiratory failure?
cord-287758-da11ypiyThe possible mechanisms of action of 4-aminoquinolines( chloroquine/ hydroxychloroquine) against Sars- Cov-2 infection( COVID-19): A role for iron homeostasis?
cord-287758-da11ypiyThe world is facing a huge challenge in the coronavirus disease( COVID-19) pandemic: How to fight an enemy without weapons in terms of therapy?
cord-289003-vov6o1jxAlso, is it the right strategy in that it banks more on cure than on anticipation?
cord-289003-vov6o1jxAre there geographic areas in which these emerging infections are more frequently or widely observed today?
cord-289003-vov6o1jxAre there more cases today?
cord-289003-vov6o1jxAre we witnessing an increased frequency of EIDs appearance?
cord-289003-vov6o1jxBased on this, is it possible to prevent the virus'transmission to humans?
cord-289003-vov6o1jxCan we predict patterns, or rules, of emergence?
cord-289003-vov6o1jxDo we possess the scientific ability to predict exactly where the next infectious epidemic will start?
cord-289003-vov6o1jxHow to provide care to patients in the case of new EIDs?
cord-289003-vov6o1jxIs it possible to narrow the time gap between the beginning of an epidemic and its detection by the healthcare services?
cord-289003-vov6o1jxWhat are governments doing faced with this type of threat when the demands on the part of the population are ever- increasing?
cord-289003-vov6o1jxWhat are the major factors in the emergence of new infectious pathogens in humans?
cord-289003-vov6o1jxWhat has been, or is, the extent of nosocomial infection's role in the transmission of SARS- CoV and MERS- CoV?
cord-341620-nmrkhx5tAre we going in the right direction?
cord-341620-nmrkhx5tCOVID-19-What should anaethesiologists and intensivists know about it?
cord-341620-nmrkhx5tCan atmospheric pollution be considered a co- factor in extremely high level of SARS- CoV-2 lethality in Northern Italy?
cord-341620-nmrkhx5tCan nanotechnology and materials science help the fight against SARS- CoV-2?
cord-341620-nmrkhx5tcord-341620-nmrkhx5 t authors: Chirico, Francesco; Sacco, Angelo; Bragazzi, Nicola Luigi; Magnavita, Nicola title: Can Air- Conditioning Systems Contribute to the Spread of SARS/ MERS/ COVID-19 Infection?
cord-318935-xsfolpprHow often did you wash your hands after returning from outside during the past week? cord-318935-xsfolppr How often did you wash your hands after using the toilet during the past week?"
cord-318935-xsfolppr: Implications for gender differences?
cord-318935-xsfolpprDid you receive any education on correct hand washing or see promotional materials related to hand washing during the past year?
cord-318935-xsfolpprRelated factors of handwashing with soap and its practices by students in South Korea Handwashing with soap or alcoholic solutions?
cord-318935-xsfolpprThe impact of alcohol hand sanitizer use on infection rates in an extended care facility How often do you wash your hands?
cord-318935-xsfolpprTo evaluate hand- washing frequency, we used three questions:"How often did you wash your hands before having a meal during the past week?"
cord-318935-xsfolpprTo evaluate hand- washing methods, we used the question,"How often do you usually wash your hands with soap or hand sanitizer?"
cord-337825-ujq9mxk7Does this peptide loop impact on the entry pathway type of SARS- CoV-2, compared to other known betacoronavirus lineage B?
cord-337825-ujq9mxk7Is it possible that it invades host cells via additional novel routes, not limited to ACE2?
cord-337825-ujq9mxk7Is there an S- like protein involved in invasion?
cord-337825-ujq9mxk7The SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-337825-ujq9mxk7Therefore, which are exactly the cell types that SARS- CoV-2 may attack?
cord-337825-ujq9mxk7the global RNA virome Classify viruses- the gain is worth the pain Detection of a group 2 coronavirus in dogs with canine infectious respiratory disease Human coronaviruses: what do they cause?
cord-344330-zsx7wfyjA previously undescribed coronavirus associated with respiratory disease in humans Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children Understanding human coronavirus HCoV- NL63 Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia More and more coronaviruses: human coronavirus HKU1 Clinical and molecular epidemiological features of coronavirus HKU1-associated community- acquired pneumonia Coronavirus HKU1 and other coronavirus infections in Hong Kong Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real- time PCR method Coronavirus HKU1 infection in the United States Evidence of human coronavirus HKU1 and human bocavirus in Australian children Detection of the new human coronavirus HKU1: a report of 6 cases Coronavirus HKU1 in children, Brazil Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Middle East respiratory syndrome Middle East respiratory syndrome coronavirus: a case- control study of hospitalized patients Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection MERS in South Korea and China: a potential outbreak threat?
cord-344330-zsx7wfyjCan coronavirus undergo recombination in animal hosts other than camels?
cord-344330-zsx7wfyjDoes IBV change slowly despite the capacity of the spike protein to vary greatly?
cord-344330-zsx7wfyjIs there a way to predict the potential emergence of a novel recombinant coronavirus in the human population?
cord-344330-zsx7wfyjthe prevalence of HCoVs already circulating within the animal population,( ii) the commonality of coronavirus recombination in animals,( iii) animals which may potentially serve as mixing vessels for the generation of novel recombinant How common is coronavirus recombination in animals?
cord-339152-wfakzb6w: where are we?
cord-339152-wfakzb6wCOVID-19 Trained innate immunity not always amicable Scores of coronavirus vaccines are in competition-how will scientists choose the best?
cord-339152-wfakzb6wCovid-19: what do we know so far about a vaccine?
cord-339152-wfakzb6wHow severe and prevalent are Ebola and Marburg viruses?
cord-354474-hbl2ywixA case- control study with service and research implications for immunopsychiatry Is returning to work during the COVID-19 pandemic stressful?
cord-354474-hbl2ywixForecasting COVID-19 impact on hospital bed- days, ICU- days, ventilator- days and deaths by US state in the next 4 months Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease( COVID-19) epidemic among the general population in China Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown?
cord-354474-hbl2ywixHow essential is to focus on physician's health and burnout in coronavirus( COVID-19) pandemic?
cord-354474-hbl2ywixHow will country- based mitigation measures influence the course of the COVID-19 epidemic?
cord-331228-wbd0s4fo-What antivirals and vaccines are to be used in humans?
cord-331228-wbd0s4fo-What infection control measures are needed in healthcare settings to prevent nosocomial outbreaks?
cord-331228-wbd0s4fo: a report of nosocomial transmission Is MERS another SARS?
cord-331228-wbd0s4foIn all, public health, veterinary health, and research efforts need to be consolidated in order to answer the following high priority questions:-What is the true extent of human infection with MERS- CoV?
cord-331228-wbd0s4foif so, how?
cord-331228-wbd0s4fomeasures need to be in place in order to prevent zoonotic infections from camels?
cord-331228-wbd0s4foother animal species involved in the MERS- CoV transmission cycle?
cord-327063-ea7a1xflAvian influenza and sialic acid receptors: more than meets the eye?
cord-327063-ea7a1xflBased on SARS- CoV Immunological Studies Is COVID-19 receiving ADE from other coronaviruses?
cord-327063-ea7a1xflCOVID-19: what is next for public health?
cord-327063-ea7a1xflCompanion Animal Pets Is COVID-19 the first pandemic that evolves into a panzootic?
cord-327063-ea7a1xflFirst respiratory transmitted food borne outbreak?
cord-327063-ea7a1xflThe Indian journal of animal sciences MERS- CoV and now the 2019-novel CoV: Have we investigated enough about coronaviruses?
cord-327063-ea7a1xflThe SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-327063-ea7a1xflWhat can animal coronaviruses tell us about emerging human coronaviruses?
cord-305422-t8azymo7After 2019-nCoV Infection Applications of acute phase reactants in infectious diseases Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum Lactate dehydrogenase in sickle cell disease Induction of proinflammatory cytokines in human macrophages by influenza A( H5N1) viruses: a mechanism for the unusual severity of human disease?
cord-305422-t8azymo7Although molecular modeling and biochemical assays have demonstrated that SARS- CoV-2 binds to ACE2, how exactly does the virus enter the airway cells and cause subsequent pathological changes?
cord-305422-t8azymo7Do N95 respirators provide 95% protection level against airborne viruses, and how adequate are surgical masks?
cord-305422-t8azymo7Does the virus also bind ACE2-expressing cells in other organs[ 121]?
cord-305422-t8azymo7How is the virus genetically evolving during transmission among humans?
cord-305422-t8azymo7How long will the epidemic last?
cord-305422-t8azymo7Should the quarantine time be extended to 24 days?
cord-305422-t8azymo7The spike protein of SARS- CoV-- a target for vaccine and therapeutic development SARS vaccines: where are we?
cord-305422-t8azymo7What animal was the intermediate species to transmit the virus from the original host, say bats, to humans?
cord-305422-t8azymo7Will it become a pandemic worldwide, die down like SARS or relapse periodically like the flu?
cord-305422-t8azymo7• Where did SARS- CoV-2 come from?
cord-319780-rfj9t99rA molecular docking study Can angiotensin receptor- blocking drugs perhaps be harmful in the COVID-19 pandemic?
cord-319780-rfj9t99rFor example, what are the mechanism/ s underlying why some sufferers of hypertension and/or diabetes might be at higher risk( https://www.immunopaedia.org.za/breakingnews/why-are-hypertension-and-diabetes-patients-at-high-risk-of-severe-covid-19/)?
cord-319780-rfj9t99rHow will the evolution of the virus alter rates of infection and the severity of symptoms?
cord-319780-rfj9t99rIs nicotine exposure linked to cardiopulmonary vulnerability to COVID-19 in the general population?
cord-319780-rfj9t99rIs there evidence from the SARS and MERS outbreaks to suggest a commonality of susceptibility?
cord-319780-rfj9t99rIs there evidence that patients on ACE inhibitors or angiotensin receptor blockers were at higher risk with SARS- CoV and MERS- CoV infections and, currently, for SARS- CoV-2 infection?
cord-319780-rfj9t99rN is a receptor for human coronavirus 229E Enteric involvement of coronaviruses: is faecal- oral transmission of SARS- CoV-2 possible?
cord-319780-rfj9t99rUnderestimated Opportunistic Pathogens of the Central Nervous System?
cord-319780-rfj9t99rWhat factor/ s determine resistance to infection?
cord-319780-rfj9t99rWhat is the impact of contracting the virus on individuals with other underlying conditions?
cord-354738-4rxradwzA framework for analysis Here a virus, there a virus, everywhere the same virus?
cord-354738-4rxradwzAnd is the zoonotic risk posed by bats decreased accordingly?
cord-354738-4rxradwzAre fewer viruses prevalent in European bats because of the lower abundance of species in the more temperate Europe?
cord-354738-4rxradwzIn Food Security in a Global Economy Veterinary Medicine and Public Health Bats and viruses: A brief review Mass extinctions, biodiversity and mitochondrial function: Are bats-special‖ as reservoirs for emerging viruses?
cord-354738-4rxradwzMicrobial biogeography?
cord-349812-nw1nlc1yDid you reduce or avoid outdoor activities or attend meetings this week because of MERS- CoV or COVID-19?
cord-349812-nw1nlc1yDid you reduce or avoid visiting crowded markets, departmental stores, or large discount stores this week because of MERS- CoV or COVID-19?Transmission- reducing practice was assessed using the following two questions: 1)"Do you wash your hands more often than usual because of MERS- CoV or COVID-19?"and 2)"Have you ever worn a face mask because of MERS- CoV or COVID-19?"
cord-349812-nw1nlc1yDid you reduce or avoid visiting crowded markets, departmental stores, or large discount stores this week because of MERS- CoV or COVID-19?Transmission- reducing practice was assessed using the following two questions: 1)"Do you wash your hands more often than usual because of MERS- CoV or COVID-19?"and 2)"Have you ever worn a face mask because of MERS- CoV or COVID-19?"
cord-349812-nw1nlc1yDid you reduce or avoid visiting crowded markets, departmental stores, or large discount stores this week because of MERS- CoV or COVID-19?Transmission- reducing practice was assessed using the following two questions: 1)"Do you wash your hands more often than usual because of MERS- CoV or COVID-19?"and 2)"Have you ever worn a face mask because of MERS- CoV or COVID-19?"
cord-349812-nw1nlc1y; 2)"Did you reduce or avoid using public transportation such as the bus or the subway this week because of MERS- CoV or COVID-19?"; 3)"Did you reduce or avoid using healthcare facilities such as the hospitals or public health centers this week because of MERS- CoV or COVID-19?"; and 4)
cord-349812-nw1nlc1y; 2)"Did you reduce or avoid using public transportation such as the bus or the subway this week because of MERS- CoV or COVID-19?"; 3)"Did you reduce or avoid using healthcare facilities such as the hospitals or public health centers this week because of MERS- CoV or COVID-19?"; and 4)
cord-353732-7hjsux4mClinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection Hyperimmune IV immunoglobulin treatment: a multicenter double- blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection SARS: systematic review of treatment effects Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A( H1N1) 2009 virus infection Meta- analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?
cord-353732-7hjsux4mDo you believe that patients at your hospital would participate in randomized studies in which patients are randomly assigned to one of two or more treatments?").
cord-353732-7hjsux4mDo you have a mechanism to send specific blood donors( e.g., survivors of MERS- CoV infection) to the blood bank to make donations?"
cord-353732-7hjsux4mFirst, four questions aimed to evaluate the ability and capacity of caring for critically ill patients within the KSA health system( e.g.,"How many beds are capable of caring for mechanically ventilated patients in the ICU where patients with severe acute respiratory infection( SARI) would usually be treated?").
cord-353732-7hjsux4mand"What methodologies are available in the laboratories associated with your site for MERS- coV testing?").
cord-289520-i6pv90s9What are risk factors for death or severe illness?
cord-289520-i6pv90s9What are the risk factors for death or severe illness?
cord-289520-i6pv90s9What are the risk factors for death or severe illness?
cord-289520-i6pv90s9What are the risk factors for infection( in patient population)?
cord-289520-i6pv90s9What characteristics define a"case"?
cord-289520-i6pv90s9What is the causative agent of disease?
cord-289520-i6pv90s9What is the causative agent of disease?
cord-289520-i6pv90s9What is the causative agent of disease?
cord-289520-i6pv90s9What is the clinical presentation and spectrum of disease?
cord-289520-i6pv90s9What is the duration of viral shedding?
cord-289520-i6pv90s9What is the optimal diagnostic test for detecting the virus?
cord-289520-i6pv90s9What is the optimal diagnostic test?
cord-289520-i6pv90s9What is the role of antivirals in treatment?
cord-289520-i6pv90s9What is the role of steroids in treatment?
cord-289520-i6pv90s9What risk factors pre- dispose health care workers to infection or transmission?
cord-289520-i6pv90s9What treatments are effective?
cord-346389-gbmnoo84COVID-19 and diabetes: can DPP4 inhibition play a role?
cord-346389-gbmnoo84COVID-19) The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS- CoV-2 Pulmonary embolism or pulmonary thrombosis in COVID-19?
cord-346389-gbmnoo84Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS- CoV Remdesivir in adults with severe COVID-19: a randomised, double- blind, placebo- controlled, multicentre trial Gilead Announces Results From Phase 3 Trial of Remdesivir in Patients With Moderate COVID-19 Available online at Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus Survival after mesenchymal stromal cell therapy in steroidrefractory acute graft- versus- host disease: systematic review and metaanalysis Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia Extraordinary GUrich single- strand RNA identified from SARS coronavirus contributes an excessive innate immune response Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment Effective treatment of severe COVID-19 patients with tocilizumab Favorable changes of CT findings in a patient with COVID-19 pneumonia after treatment with tocilizumab Tocilizumab, an anti- IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab Dissection of the effects of jak and btk inhibitors on the functionality of healthy and malignant lymphocytes COVID-19: combining antiviral and anti- inflammatory treatments Baricitinib for COVID-19: a suitable treatment?
cord-346389-gbmnoo84Do men have a higher case fatality rate of severe acute respiratory syndrome than women do?
cord-346389-gbmnoo84Is the recommendation to use high- dose heparin for thromboprophylaxis justified?
cord-346389-gbmnoo84Where are we?
cord-346389-gbmnoo84the battle continues Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-349287-mwj2qby4: can we go from bench to bedside?
cord-349287-mwj2qby4Nucleocapsid Antibody, Mouse MAb Is MERS another SARS?
cord-349287-mwj2qby4Researchers sought to determine a direction for infection; were DCs transmitting virus to humans or were humans infecting DCs?
cord-349287-mwj2qby4South Korea's MERS response questioned Intensified public health measures help control MERS- CoV outbreak in the Republic of Korea South Korean MERS outbreak spotlights lack of research Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus Isolated in South Korea Complete Genome Sequence of Middle East Respiratory Syndrome Coronavirus( MERS- CoV) from the First Imported MERS- CoV Case in China Urgent Call for Research on Middle East Respiratory Syndrome( MERS) in Korea Middle East respiratory syndrome( MERS) in Asia: lessons gleaned from the South Korean outbreak No Respite for Korean Economy Even as MERS Patients Recover Middle East respiratory syndrome coronavirus( MERS- CoV)-China MERS in South Korea and China: a potential outbreak threat?
cord-349287-mwj2qby4The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus Viability of Pseudomonas aeruginosa in cough aerosols generated by persons with cystic fibrosis Middle East respiratory syndrome coronavirus: transmission and phylogenetic evolution Middle East respiratory syndrome coronavirus: epidemic potential or a storm in a teacup?
cord-349287-mwj2qby4WHO Statement MERS- CoV in Upper Respiratory Tract and Lungs of Dromedary Camels, Saudi Arabia Evidence for camel- to- human transmission of MERS coronavirus Taking stock of the first 133 MERS coronavirus cases globally- Is the epidemic changing?
cord-349287-mwj2qby4Why the panic?
cord-320663-xypg6evoActivating KIRs and NKG2C in viral infections: toward NK cell memory?
cord-320663-xypg6evoAre patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-320663-xypg6evoCOVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting?
cord-320663-xypg6evoDoes COVID-19 spread through droplets alone?
cord-320663-xypg6evoHave I found the missing ingredient in a coronavirus vaccine?
cord-320663-xypg6evoHow is immunosuppressive status affecting children and adults in SARS- CoV-2 infection?
cord-320663-xypg6evoThe SARS, MERS and novel coronavirus( COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
cord-320663-xypg6evoThe innate immune system: fighting on the front lines or fanning the flames of COVID-19?
cord-320663-xypg6evoThe role of the interleukin-1 family in trained immunity Training the trainable cells of the immune system and beyond BCG- induced trained immunity: can it offer protection against COVID-19?
cord-320663-xypg6evoThe trafficking of natural killer cells Keeping NK cells in highly regulated antiviral warfare Human NK cell lytic granules and regulation of their exocytosis Natural killer cells: development, maturation, and clinical utilization Natural killer cell memory in infection, inflammation and cancer About training and memory: NK- cell adaptation to viral infections Is there natural killer cell memory and can it be harnessed by vaccination?
cord-320663-xypg6evoThe use of antiinflammatory drugs in the treatment of people with severe coronavirus disease 2019( COVID-19): the perspectives of clinical immunologists from China Adjunct immunotherapies for the management of severely Ill COVID-19 patients HiJAKing SARS- CoV-2?
cord-320663-xypg6evointerferon responses: from friend to foe in the battle against chronic viral infection NK cells and interferons Innate or adaptive immunity?
cord-313737-cob5hf5qAlso, how do you go about producing good guidelines?
cord-313737-cob5hf5qBut can we expect a randomized controlled trial for everything?
cord-313737-cob5hf5qBut what do we do about the more controversial areas: decolonization, screening of staff, cohorting staff and patients, environment screening, and education?
cord-313737-cob5hf5qBut what has caused the rate of MRSA to fall so dramatically?
cord-313737-cob5hf5qEven for parachutes when jumping out of aeroplanes?
cord-313737-cob5hf5qHow can we invest in infection control when some hospitals ca n't afford to buy new pens?
cord-313737-cob5hf5qIs this an appropriate trade- off?
cord-313737-cob5hf5qMartin gave some useful guidance about performing an effective root cause analysis( to get to the root of the problem!): make sure the right stakeholders are around the table( junior doctors wo n't do); be a toddler( ask why?
cord-313737-cob5hf5qOne key question is: do we go universal or targeted?
cord-313737-cob5hf5qPlus, importantly, how do good guidelines translate through a good policy into good practice?
cord-313737-cob5hf5qSelf- reported hand hygiene compliance rates are usually reported to be> 90%, but who would believe this with such a huge conflict of interest?
cord-313737-cob5hf5qThis led to huge scrutiny and political drive for improvement, which has been successful contrary to the predictions of many( most?) experts!
cord-313737-cob5hf5qWhy?
cord-313737-cob5hf5qWhy?)
cord-350733-0zghspb8Beliefs underlying UK parents'views towards MMR promotion interventions: a qualitative study A systematic review of interventions for reducing parental vaccine refusal and vaccine hesitancy On the benefits of explaining herd immunity in vaccine advocacy Vaccinating to help ourselves and others Inviting free- riders or appealing to prosocial behavior?
cord-350733-0zghspb8Can this strategy be improved by taking an EBM+ approach?
cord-350733-0zghspb8Do genetic polymorphisms, 37- 39 physiological variables, diseases, and drug interactions alter it predictably?
cord-350733-0zghspb8Do strategic lesions cause predictable changes?
cord-350733-0zghspb8Does it change in response to interventions such as upregulation or downregulation?
cord-350733-0zghspb8Is hypertension in African- descent populations contributed to by an imbalance in the activities of the ACE2/ Ang-(1- 7)/Mas and the ACE/ Ang II/ AT1 axes?
cord-350733-0zghspb8a Bayesian framework for causal assessment in pharmacosurveillance Drugs and the renin- angiotensin system in covid-19 Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-350733-0zghspb8should inhibitors of the renin- angiotensin system be withdrawn in patients with COVID-19?
cord-350733-0zghspb8• When any changes occur, is dose- responsiveness maintained?
cord-338973-73a7uvyzApart from droplet transmission and contact transmission, are there other methods to transmit SARS- CoV-2?
cord-338973-73a7uvyzCan the susceptibility of asymptomatic carriers be judged by detecting the serum reactivity level of N protein?
cord-338973-73a7uvyzDo any environmental factors, such as regional conditions or climate, affect SARS- CoV-2 transmission?
cord-338973-73a7uvyzDo ethnic differences affect the transmissibility and pathogenicity of SARS- CoV-2?
cord-338973-73a7uvyzDoes SARS- CoV-2 orf8 and orf10 proteins, which have no homology proteins in SARS- CoV, play roles in the infectivity and pathogenicity of SARS- CoV-2?
cord-338973-73a7uvyzDoes traditional Chinese medicine have any effect on the treatment of COVID-19 caused by SARS- CoV-2?
cord-338973-73a7uvyzIs there an effective specific anti- SARS- CoV-2 solution?
cord-338973-73a7uvyzIs there any effect of SARS- CoV vaccine designed according to S protein on SARS- CoV-2?
cord-338973-73a7uvyzWhat is the effect of the surface epitope and receptor binding domain of S protein of SARS- CoV-2 on the virus'infectivity?
cord-338973-73a7uvyzWhat is the percentage of COVID-19 patients have been infected with SARS and produced antibodies?
cord-342756-rgm9ffpk-What happens next?
cord-342756-rgm9ffpk: what to expect for COVID-19?
cord-342756-rgm9ffpkCOVID-19 and diabetes: Can DPP4 inhibition play a role?
cord-342756-rgm9ffpkCOVID-19, SARS and MERS: are they closely related?
cord-342756-rgm9ffpkDPP4 inhibition: preventing SARS- CoV-2 infection and/or progression of COVID-19?
cord-342756-rgm9ffpkProtein- protein interactions of viroporins in coronaviruses and paramyxoviruses: new targets for antivirals?
cord-342756-rgm9ffpkThe importance of hypertension as a risk factor for severe illness and mortality in COVID-19 Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 in Wuhan, China: a retrospective study Diabetes is a risk factor for the progression and prognosis of COVID-19 Older people and COVID-19: isolation, risk and ageism Asymptomatic carriers of COVID-19 as a concern for disease prevention and control: more testing, more follow- up Drug repositioning: identifying and developing new uses for existing drugs Drug repurposing from the perspective of pharmaceutical companies Drug repurposing: progress, challenges and recommendations Emerging virus diseases: can we ever expect the unexpected?
cord-342756-rgm9ffpkand COVID-19: serendipity or opportunity for intervention?
cord-342756-rgm9ffpkshould inhibitors of the renin- angiotensin system be withdrawn in patients with COVID-19?
cord-342756-rgm9ffpkwhat lessons have we learned?
cord-279255-v861kk0i( COVID-19) outbreak: could pigs be vectors for human infections?
cord-279255-v861kk0i2019 novel coronavirus( 2019-nCoV): what advice can we give to travellers?
cord-279255-v861kk0i: what have we learned?
cord-279255-v861kk0i: what is the role of radiologists?
cord-279255-v861kk0iCOVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression Increased incidence of gastrointestinal side effects in patients taking hydroxychloroquine: a brand- related issue?
cord-279255-v861kk0iCan SARS- CoV-2 infection be acquired in utero?
cord-279255-v861kk0iCan cats become infected with Covid-19?
cord-279255-v861kk0iCan companion animals become infected with Covid-19? Leading veterinary diagnostic company
cord-279255-v861kk0iDoes SARS- CoV-2 has a longer incubation period than SARS and MERS?
cord-279255-v861kk0iHowever, the real question is, how are we planning to counter the next zoonotic CoV epidemic that is likely to occur within the next 5 to 10 years or perhaps sooner?
cord-279255-v861kk0iInfluenza Other Respir Viruses Does hand hygiene reduce SARS- CoV-2 transmission?
cord-279255-v861kk0iMore definitive evidence is needed Wuhan virus: Chinese animal markets reopened with almost no precautions China must close down"wet markets Will they ever learn?
cord-279255-v861kk0iRational vaccine design in the time of COVID-19 Bacillus Calmette Guérin( BCG) vaccination use in the fight against COVID-19-what's old is new again?
cord-279255-v861kk0iReply to"Does hand hygiene reduce SARS- CoV-2 transmission?
cord-279255-v861kk0iThe establishment of reference sequence for SARS- CoV-2 and variation analysis Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
cord-279255-v861kk0iThe next big threat to global health?
cord-279255-v861kk0iWhat do we know about the SARS- CoV-2 coronavirus in the environment?
cord-279255-v861kk0iWhat is the potential impact of the Amazon wildfires on vector- borne and zoonotic emerging diseases?
cord-279255-v861kk0iand now the 2019-novel CoV: have we investigated enough about coronaviruses?
cord-279255-v861kk0ie12591 Infection and rapid transmission of SARS- CoV-2 in ferrets Current therapeutic applications and pharmacokinetic modulations of ivermectin Hydroxychloroquine and ivermectin: a synergistic combination for COVID-19 chemoprophylaxis and/or treatment?
cord-279255-v861kk0iis faecal- oral transmission of SARS- CoV-2 possible?
cord-279255-v861kk0iproactive infection control measures against the emerging Wuhan coronavirus pneumonia in China Emerging viruses without borders: the Wuhan coronavirus China coronavirus: what do we know so far?
cord-018504-qqsmn72uThe type of public health professional required to address this specific public health issue includes, but is not limited to, the following: asymptomatic, mild, severe infection)?
cord-018504-qqsmn72uWhat is the best clinical management of MERS- CoV?
cord-018504-qqsmn72uWhat is the infection rate in the community?•"What are the protective immune system mechanisms against MERS- CoV?"•"What is the excretion pattern of the virus?"
cord-018504-qqsmn72uWhat is the infection rate in the community?•"What are the protective immune system mechanisms against MERS- CoV?"•"What is the excretion pattern of the virus?"
cord-018504-qqsmn72uWhat is the infection rate in the community?•"What are the protective immune system mechanisms against MERS- CoV?"•"What is the excretion pattern of the virus?"
cord-018504-qqsmn72uWhat is the natural reservoir of MERS- CoV?•"What is the source of exposure to MERS- CoV outside of the healthcare facility( e.g., animals, water, sewage, food)?
cord-018504-qqsmn72uWhat is the natural reservoir of MERS- CoV?•"What is the source of exposure to MERS- CoV outside of the healthcare facility( e.g., animals, water, sewage, food)?
cord-018504-qqsmn72uAre there primary and secondary prevention tools we could implement and evaluate in our community?
cord-018504-qqsmn72uAre there refugee resettlement services developed by resettled refugees who can assist with contacting an often hard- to- reach population to offer peer education?
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uAsk your workforce or students, “ Are we ready to handle such an event if it were to occur here? ”; “ What resources would we need to have accessible? ”; “ Have we partnered with the correct agencies in the community? ”; “ Do we have an established, trusted presence in the community? ”; “ Who else do we need on our team? ”; “ Do we need training in a specialty area, e.g., emergency preparedness? ”; “ What skills have we mastered and what skills do we need to obtain? ”
cord-018504-qqsmn72uDid the hospital conduct a thorough background check?
cord-018504-qqsmn72uDo we have a policy to prevent drug diversion in the workplace?
cord-018504-qqsmn72uDoes the community have a plan to address this public health issue?
cord-018504-qqsmn72uHas the community, who lives with the issue( i.e., refugees,"working poor"), been invited to participate with public health practitioners?
cord-018504-qqsmn72uHow can we do a better job in protecting our patients?
cord-018504-qqsmn72uHow can we partner more effectively with law enforcement and drug rehabilitation centers, for example?
cord-018504-qqsmn72uHow can we see"red flags"before the individual of concern is hired?
cord-018504-qqsmn72uHow could we prevent children from being poisoned by lead in our community considering that practical solutions are difficult to implement due to the high cost of lead- abatement measures?
cord-018504-qqsmn72uHow does the refugee resettlement process exacerbate CLP?
cord-018504-qqsmn72uHow is drug diversion a public health problem, as well as a health- care problem?
cord-018504-qqsmn72uHow will we provide lead prevention education for families for whom English is not their first language?
cord-018504-qqsmn72uHow will you access these data?
cord-018504-qqsmn72uHow will you conduct surveillance of the public health issue?
cord-018504-qqsmn72uHow would you amend the current( if any) lead housing policies in your community or state?
cord-018504-qqsmn72uHow would you educate about a serious public health issue, such as CLP, for which there are no visible signs or symptoms until there is an EBLL?
cord-018504-qqsmn72uHow would you engage the refugee resettlement agencies, the social service agencies developed by refugees, and the refugees themselves in a coordinated effort to reduce CLP?
cord-018504-qqsmn72uHow would you engage this social service agency?
cord-018504-qqsmn72uHow would you establish such a community group if one does not exist?
cord-018504-qqsmn72uHow would you know what the newly resettled refugee concerns are and how they compare to their counterparts who have been living in the community for a period of time?
cord-018504-qqsmn72uHow would you partner with an academic institution with public health expertise to assist with providing knowledge, expertise, and resources?
cord-018504-qqsmn72uHow would you partner with the local health- care system( i.e., community health centers, hospitals, physician practices) to assure that they are following CDC testing guidelines and to assist with consistent outreach and prevention education efforts?
cord-018504-qqsmn72uIf a stakeholder refuses to come to the"table"to work on the issue because they believe the issue is either not under their purview or is too complex to address, how would you engage this key partner?
cord-018504-qqsmn72uIf so, how can we improve the policy?
cord-018504-qqsmn72uIf so, how?
cord-018504-qqsmn72uIf this tragic event occurred in your community, what questions would you ask?
cord-018504-qqsmn72uIf we addressed CLP in the community, what other public health issues could potentially be lessened or mitigated?
cord-018504-qqsmn72uIs there a community coalition formed to work on monitoring the issue and connecting families with testing services?
cord-018504-qqsmn72uIs there a reporting system in place so that other hospitals across the country could be notified about the infected individual's reason for termination?
cord-018504-qqsmn72uIs there a system in place for employees to report suspicious behavior to senior management and human resources?
cord-018504-qqsmn72uLessons Learned The main question is how do we, as public health practitioners and educators, work collaboratively with our partners in the health- care system to prevent antibiotic resistance in the health- care setting and the community?
cord-018504-qqsmn72uLessons Learned: If this unfortunate event occurred in your hospital, what questions would you ask?
cord-018504-qqsmn72uPublic Health Emergency?
cord-018504-qqsmn72uShould a public registry for those health- care workers found guilty of drug diversion be created at the national level?
cord-018504-qqsmn72uShould access to such a registry be limited to health- care hiring agencies?
cord-018504-qqsmn72uShould communities with refugee children poisoned by lead request a moratorium for refugee resettlement until the community can provide quality housing that does not pose a health risk?
cord-018504-qqsmn72uShould termination of employment be implemented if an employee refuses to cooperate with this policy?
cord-018504-qqsmn72uShould the penalty for engaging in drug diversion be suspension or removal of one's license or certification to practice their skill in a health- care setting?
cord-018504-qqsmn72uShould the public also have access to this registry?
cord-018504-qqsmn72uShould the refugee resettlement process be redesigned?
cord-018504-qqsmn72uShould there be incentives to report employees observed in negligent behavior?
cord-018504-qqsmn72uShould we implement mandatory, unannounced drug testing for all hospital employees who engage in patient contact?
cord-018504-qqsmn72uWhat are our hiring processes?
cord-018504-qqsmn72uWhat are the implications of a moratorium for the resettled refugees and the community?
cord-018504-qqsmn72uWhat data should you be collecting?
cord-018504-qqsmn72uWhat other partners in the public health system should be involved in this issue?
cord-018504-qqsmn72uWhat stakeholders in the public health system should be invited to address the problem?
cord-018504-qqsmn72uWho is the"keeper"of the data?
cord-018504-qqsmn72uWho should be involved in the hiring process?
cord-018504-qqsmn72uWhom would you work with to develop and enact such policies?
cord-018504-qqsmn72uWhy did the staffing agency not disclose the issues with this employee?
cord-018504-qqsmn72uWhy or why not?
cord-018504-qqsmn72uWith so many competing demands on the public health system, and the fact that CLP is a persistent public health problem that the community has lived with for generations, and the costly abatement measures- should CLP be in the"top ten"of issues for communities, similar to Manchester, NH, to be concerned about?
cord-018504-qqsmn72uWould public health enforcement laws be necessary( i.e., citations for property owners who do not comply with the developed policy)?
cord-018504-qqsmn72u• How could a medical technician with a suspect record be passed from hospital to hospital?
cord-018504-qqsmn72u•"How can we efficiently disinfect against MERS- CoV?
cord-018504-qqsmn72u•"How stable is MERS- CoV under different environmental conditions( e.g., dry surface, in vomit, sputum or diarrhea)?"
cord-018504-qqsmn72u•"Is there a role for antiviral agents?"
cord-018504-qqsmn72u•"Is there a role for herd immunity against MERS- CoV?