quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
middle east respiratory syndrome	6092
east respiratory syndrome coronavirus	4733
severe acute respiratory syndrome	2409
of middle east respiratory	1902
acute respiratory syndrome coronavirus	1046
respiratory syndrome coronavirus infection	729
of severe acute respiratory	725
the middle east respiratory	575
respiratory syndrome coronavirus in	444
with middle east respiratory	413
acute respiratory distress syndrome	412
for the treatment of	365
of a novel coronavirus	363
for middle east respiratory	307
a novel coronavirus from	291
in the middle east	278
the severe acute respiratory	278
outbreak of middle east	274
with severe acute respiratory	270
the republic of korea	257
of the middle east	243
novel coronavirus from a	229
pneumonia in saudi arabia	228
isolation of a novel	226
from a man with	226
a man with pneumonia	225
the world health organization	224
with pneumonia in saudi	224
disease control and prevention	224
coronavirus from a man	224
man with pneumonia in	223
for disease control and	215
patients with middle east	213
in the republic of	211
in the treatment of	209
syndrome coronavirus infection in	203
critically ill patients with	195
kingdom of saudi arabia	194
in the united states	193
in the context of	191
in the case of	185
in patients with severe	183
cases of middle east	179
in the absence of	166
arabia middle east respiratory	165
saudi arabia middle east	165
on the other hand	164
outbreak in south korea	160
and clinical characteristics of	159
centers for disease control	159
in the presence of	159
a functional receptor for	154
patients with severe acute	151
as well as the	150
in dromedary camels in	149
infection prevention and control	142
characteristics of cases of	141
is a functional receptor	141
clinical characteristics of cases	138
functional receptor for the	138
hospital outbreak of middle	137
the lower respiratory tract	137
the treatment of covid	134
case of middle east	133
for the development of	130
respiratory syndrome coronavirus infections	130
and middle east respiratory	126
the spike protein of	124
in the arabian peninsula	120
with acute respiratory distress	120
in the lungs of	118
in vitro and in	118
of the spike protein	118
was found to be	117
the kingdom of saudi	117
the upper respiratory tract	114
respiratory syndrome coronavirus disease	113
respiratory syndrome coronavirus spike	112
coronavirus in dromedary camels	111
of patients infected with	111
at the time of	110
infection in dromedary camels	109
in saudi arabia middle	109
a systematic review and	109
east respiratory syndrome in	109
outbreak in the republic	108
acute respiratory syndrome in	108
an important role in	108
respiratory syndrome coronavirus and	107
has been shown to	106
coronavirus middle east respiratory	106
of critically ill patients	106
human transmission of mers	104
it is important to	104
in the respiratory tract	103
on the basis of	103
from the middle east	99
the emerging human coronavirus	99
dipeptidyl peptidase is a	99
of cases of middle	98
peptidase is a functional	98
for the emerging human	98
receptor for the emerging	98
in patients with covid	97
antibodies in dromedary camels	97
were found to be	95
coronavirus disease from saudi	95
vitro and in vivo	95
syndrome coronavirus disease from	95
disease from saudi arabia	95
a l p r	94
p r o o	94
u r n a	94
o u r n	94
l p r e	94
n a l p	94
r o o f	94
j o u r	94
r n a l	94
of the novel coronavirus	94
the united arab emirates	92
as a result of	92
in addition to the	92
infection with middle east	91
have been shown to	91
camels in saudi arabia	89
associated with acute respiratory	89
the s protein of	88
transmission of mers coronavirus	87
the mers outbreak in	87
isolation and characterization of	86
modified vaccinia virus ankara	86
systematic review and meta	86
in the upper respiratory	85
in the development of	84
dromedary camels in saudi	84
against middle east respiratory	83
transcription polymerase chain reaction	82
of the s protein	81
porcine epidemic diarrhea virus	81
the middle east and	81
of the severe acute	81
mers coronavirus in dromedary	80
from patients with pneumonia	80
a large number of	80
of the novel human	78
the spread of the	78
influenza a h n	78
transmission of middle east	78
syndrome coronavirus spike protein	77
in severe acute respiratory	77
in saudi arabia in	76
a retrospective cohort study	76
in the kingdom of	76
caused by a novel	75
one of the most	75
ill patients with middle	75
cluster of middle east	74
clinical features of patients	73
mers outbreak in korea	73
study middle east respiratory	72
for severe acute respiratory	72
respiratory distress syndrome in	72
is one of the	72
a wide range of	72
at the end of	71
family cluster of middle	71
the total number of	71
have been reported to	71
identification of a novel	71
infected with novel coronavirus	71
a systematic review of	71
during the mers outbreak	70
cov outbreak in south	70
patients infected with novel	69
with novel coronavirus in	69
in the number of	69
features of patients infected	68
for the detection of	68
syndrome coronavirus in dromedary	68
of novel coronavirus pneumonia	67
transmission of the virus	67
course and outcomes of	67
of the sars coronavirus	67
clinical course and outcomes	67
coronavirus infection in dromedary	67
lower respiratory tract infection	67
a novel human coronavirus	66
serum antibodies in dromedary	66
in the lower respiratory	66
as well as in	66
coronavirus in saudi arabia	66
a mouse model for	66
of hospitalized patients with	66
a comparative serological study	66
in the spike protein	65
as shown in figure	65
outcomes of critically ill	65
to severe acute respiratory	65
play an important role	65
cov infection in a	64
by a novel coronavirus	64
and outcomes of critically	64
with the middle east	64
of a case of	63
can be used to	63
been shown to be	63
novel coronavirus in wuhan	62
coronavirus neutralising serum antibodies	62
respiratory syndrome coronavirus neutralising	62
neutralising serum antibodies in	62
middle eastern respiratory syndrome	62
syndrome coronavirus neutralising serum	62
in saudi arabia and	61
outbreak of severe acute	61
patients with severe covid	61
the end of the	61
to middle east respiratory	61
to the middle east	60
have been reported in	60
on the surface of	60
of sars and mers	60
efficacy and safety of	60
confirmed cases of mers	60
syndrome coronavirus middle east	59
has been reported to	59
the innate immune response	59
the receptor binding domain	59
patients with pneumonia in	59
saudi ministry of health	59
similar to that of	59
at the same time	59
coronavirus from patients with	59
novel coronavirus from patients	59
in the present study	59
the development of a	59
respiratory syndrome coronavirus middle	59
and characterization of a	58
of a novel human	58
during the course of	58
genomic characterization of a	58
in middle east respiratory	58
in vero e cells	58
of the virus in	58
with pneumonia in china	58
studies have shown that	58
in a mouse model	57
the intensive care unit	57
treatment of severe acute	57
inflammatory cytokines and chemokines	57
for the first time	56
with the novel coronavirus	56
entry into host cells	56
h n influenza virus	56
and epidemiology of novel	56
human betacoronavirus c emc	56
no conflict of interest	56
the treatment of sars	56
epidemiology of novel coronavirus	56
a novel coronavirus in	56
it is possible that	56
for critically ill patients	55
for virus origins and	55
a newly discovered coronavirus	55
human middle east respiratory	55
with a new coronavirus	55
coronavirus in patients with	55
cases of infection with	55
outcomes of patients with	55
implications for virus origins	55
severe middle east respiratory	55
respiratory tract infection in	54
cases have been reported	54
virus origins and receptor	54
the coronavirus study group	54
coronavirus infection in the	54
were more likely to	54
outbreak associated with a	54
origins and receptor binding	54
for the presence of	54
patients infected with sars	54
of a newly discovered	53
spread of the virus	53
who has granted medrxiv	53
discovered coronavirus associated with	53
characterisation and epidemiology of	53
a license to display	53
cov outbreak in jeddah	53
to health care facilities	53
distress syndrome in humans	53
the human respiratory tract	53
of probable bat origin	53
a new coronavirus of	53
link to health care	53
newly discovered coronavirus associated	53
spike protein of sars	53
the treatment of severe	53
pneumonia outbreak associated with	53
coronavirus of probable bat	53
medrxiv a license to	53
display the preprint in	53
granted medrxiv a license	53
a pneumonia outbreak associated	53
license to display the	53
treatment of middle east	53
the onset of symptoms	53
the authors declare that	53
center for disease control	53
associated with a new	53
to display the preprint	53
has granted medrxiv a	53
respiratory syndrome coronavirus replication	53
coronavirus associated with acute	53
new coronavirus of probable	53
by the world health	52
a link to health	52
characterization of a newly	52
genomic characterisation and epidemiology	52
the binding of the	52
respiratory syndrome coronavirus as	52
upper and lower respiratory	52
novel coronavirus associated with	51
cause of severe acute	51
of patients with covid	51
camels middle east respiratory	51
model for middle east	51
the spread of mers	51
the role of the	50
patients with novel coronavirus	50
a case of middle	50
the case fatality rate	50
and severe acute respiratory	50
against mers coronavirus in	50
the first case of	50
binding domain complexed with	50
the authors declare no	50
antibodies against mers coronavirus	50
cases of novel coronavirus	50
a novel coronavirus associated	49
in balb c mice	49
cd and cd t	49
and cd t cells	49
as the gene source	49
east respiratory syndrome outbreak	49
respiratory syndrome coronavirus transmission	49
has been reported in	49
of convalescent plasma therapy	49
s protein of sars	49
the course of the	49
the gene source of	49
in patients with middle	48
in patients infected with	48
and virological analysis of	48
analysis of a case	48
these results suggest that	48
in critically ill patients	48
after the onset of	48
in upper respiratory tract	48
and evolution of the	48
clinical features and virological	48
cov infection in dromedary	48
of patients with severe	48
virological analysis of a	48
of the coronavirus study	48
epidemiological and clinical characteristics	48
and the middle east	48
important role in the	48
features and virological analysis	48
this work was supported	48
and cellular immune responses	47
patients with coronavirus disease	47
there is no evidence	47
work was supported by	47
cytokines and chemokines in	47
respiratory syndrome coronavirus by	47
to the world health	47
are more likely to	47
korea middle east respiratory	47
to better understand the	47
detection of a novel	47
outbreaks of middle east	47
the efficacy and safety	47
novel middle east respiratory	46
patients infected with the	46
novel coronavirus pneumonia in	46
the preprint in perpetuity	46
crystal structure of the	46
respiratory syndrome in hong	46
used in this study	46
syndrome in hong kong	46
coronaviruses as the gene	46
the presence of mers	46
korea centers for disease	46
the basic reproduction number	46
syndrome coronavirus in bats	46
the saudi ministry of	46
a nonhuman primate model	46
in a nonhuman primate	46
and shortness of breath	46
infection in the united	45
and lower respiratory tract	45
to be associated with	45
syndrome middle east respiratory	45
for the prevention of	45
dromedary camels middle east	45
the early stage of	45
in the common marmoset	45
the copyright holder for	45
influenza a and b	45
coronavirus associated with severe	45
novel human coronavirus by	45
of the mers outbreak	44
of cases of novel	44
cov infection in humans	44
the number of cases	44
coronavirus pneumonia in wuhan	44
was supported by the	44
in the human population	44
of novel human coronavirus	44
copyright holder for this	44
rna was detected in	44
the antiviral activity of	44
diagnosis and treatment of	44
and the number of	44
binding domain of mers	44
that they have no	44
associated with severe acute	44
declare that they have	44
respiratory syndrome middle east	44
case fatality rate of	44
a potent inhibitor of	44
was detected in the	44
respiratory syndrome coronavirus outbreak	44
the host immune response	44
orf a and orf	44
our understanding of the	44
the case of sars	44
infection in rhesus macaques	44
upper respiratory tract of	43
de wit et al	43
of human middle east	43
nonhuman primate model of	43
ribavirin and interferon therapy	43
entry depends on ace	43
a fatal case of	43
complete genome sequence of	43
it has been reported	43
cell entry depends on	43
depends on ace and	43
in the lungs and	43
respiratory illness caused by	43
and is blocked by	43
of the virus and	43
have been associated with	43
the s subunit of	43
is blocked by a	43
novel coronavirus in patients	43
blocked by a clinically	43
a better understanding of	43
respiratory syndrome coronavirus papain	43
the spike glycoprotein of	43
ace and tmprss and	42
ribavirin and interferon alfa	42
binding domain of the	42
authors declare that they	42
of novel coronavirus in	42
receptor for the sars	42
on ace and tmprss	42
syndrome coronavirus in saudi	42
for severe middle east	42
the results of the	42
associated with the novel	42
human coronavirus by real	42
play a role in	42
from a patient with	42
the early stages of	42
as shown in fig	42
and tmprss and is	42
in patients with mers	42
tmprss and is blocked	42
of influenza a virus	41
international committee on taxonomy	41
plays an important role	41
by a clinically proven	41
of infection with middle	41
respiratory syndrome coronavirus vaccine	41
in the united arab	41
the novel human betacoronavirus	41
and postexposure efficacy of	41
of patients with mers	41
syndrome coronavirus infection and	41
replication of middle east	41
eastern respiratory syndrome coronavirus	41
national institutes of health	41
in patients with sars	41
committee on taxonomy of	41
has been reported that	41
a clinically proven protease	41
food and drug administration	40
in the healthcare setting	40
novel human coronavirus mers	40
cov in upper respiratory	40
viral rna was detected	40
with a combination of	40
to the lack of	40
of viral rna in	40
remdesivir and chloroquine effectively	40
the recently emerged novel	40
the incubation period of	40
and outcomes of patients	40
safety and efficacy of	40
a total of patients	40
human infection with mers	40
innate and adaptive immune	40
associated outbreak of middle	40
from sars to mers	40
pp a and pp	40
recently emerged novel coronavirus	40
and chloroquine effectively inhibit	40
the sars and mers	40
on taxonomy of viruses	40
the centers for disease	40
chloroquine effectively inhibit the	40
clinically proven protease inhibitor	40
it should be noted	40
inhibit the recently emerged	40
treatment with lopinavir ritonavir	40
of patients with middle	40
for the sars coronavirus	40
effectively inhibit the recently	40
of two cases of	39
coronaviruses in dromedary camels	39
of a mouse model	39
for patients with middle	39
the arabian peninsula and	39
report of nosocomial transmission	39
two cases of infection	39
the respiratory tract of	39
respiratory syndrome in the	39
isolated from a patient	39
a report of nosocomial	39
features and viral diagnosis	39
the fact that the	39
of patients with sars	39
rapid generation of a	39
clinical features and viral	39
syndrome coronavirus in the	39
respiratory syndrome coronavirus a	39
evolution of the middle	39
presence or absence of	39
on the use of	39
diagnosis of two cases	39
clinical characteristics of hospitalized	39
sars and mers coronaviruses	39
neutralizing antibodies against mers	39
characteristics of hospitalized patients	39
the pathogenesis of sars	39
viral diagnosis of two	39
of mouse hepatitis virus	39
a randomized controlled trial	39
for laboratory confirmation of	39
enzyme is a functional	39
and viral diagnosis of	39
case of novel coronavirus	38
in the management of	38
coronavirus after exposure to	38
a and orf b	38
inhibitors of middle east	38
the beginning of the	38
with mers coronavirus after	38
primate model of common	38
is the author funder	38
infection with mers coronavirus	38
a case fatality rate	38
mers coronavirus after exposure	38
assays for laboratory confirmation	38
increase the risk of	38
hospitalized patients with novel	38
in the transmission of	38
a high prevalence of	38
in the pathogenesis of	38
after exposure to infected	38
in a patient with	38
the context of the	38
characterization of a novel	38
as severe acute respiratory	38
mediated by the viral	38
exposure to infected camels	38
discovery and therapeutic options	38
hospital in saudi arabia	38
of the immune system	38
generation of a mouse	38
the crystal structure of	38
of this study was	38
coronavirus in household contacts	38
a mortality rate of	38
reported in saudi arabia	38
transient lower respiratory tract	37
recent insights into emerging	37
in combination with ribavirin	37
respiratory syndrome coronavirus receptor	37
knowledge and data gaps	37
coronavirus in dromedary camel	37
have been detected in	37
and data gaps of	37
the treatment of mers	37
model of common marmoset	37
to that of sars	37
a role in the	37
replication and shedding of	37
of knowledge and data	37
the severity of the	37
laboratory confirmation of novel	37
by severe acute respiratory	37
syndrome coronavirus outbreak in	37
ribavirin improves outcome in	37
a and pp ab	37
from dromedary camels in	37
the ministry of health	37
confirmation of novel human	37
therapeutic efficacy of remdesivir	37
state of knowledge and	37
a family cluster of	37
mouse model for middle	37
of the s subunit	37
in close contact with	37
and shedding of mers	37
in accordance with the	37
gaps of middle east	37
data gaps of middle	37
a for severe middle	37
model of middle east	37
of ebola virus disease	37
b and ribavirin improves	37
and ribavirin improves outcome	37
insights into emerging coronaviruses	37
the risk of mers	37
improves outcome of mers	37
improves outcome in mers	37
mouse model of mers	37
during the outbreak in	37
use of convalescent plasma	37
response in patients with	37
mouse model of middle	37
respiratory syndrome coronavirus antibodies	37
holder for this preprint	37
b improves outcome of	36
article is protected by	36
ministry of health and	36
there is an urgent	36
it is necessary to	36
during the sars outbreak	36
origin and evolution of	36
for the middle east	36
infection in a nonhuman	36
is protected by copyright	36
of a family cluster	36
of the virus to	36
with lopinavir ritonavir or	36
in the form of	36
due to the lack	36
is consistent with the	36
syndrome coronavirus antibodies in	36
announcement of the coronavirus	36
a combination of interferon	36
a total of cases	36
from the arabian peninsula	36
a broad range of	36
at room temperature for	36
tested positive for mers	36
on the epidemiology of	36
illness caused by a	36
should be noted that	36
human airway epithelial cells	36
this article is protected	36
by a combination of	36
em structure of the	36
studies are needed to	36
in chinese horseshoe bats	36
the presence of the	35
drug discovery and therapeutic	35
syndrome coronavirus infections in	35
a member of the	35
of a fatal case	35
associated with middle east	35
with the exception of	35
from animals to humans	35
a middle east respiratory	35
was first reported in	35
chinese center for disease	35
pipistrellus bat coronavirus hku	35
more likely to be	35
lopinavir ritonavir or interferon	35
is closely related to	35
the first imported case	35
to that of the	35
it was found that	35
the early phase of	35
the international committee on	35
with the use of	35
from a dromedary camel	35
the novel middle east	35
have the potential to	35
and pathogenesis of coronaviruses	35
severe acute respiratory infections	35
middle east respiratory coronavirus	35
experience in saudi arabia	34
of coronavirus disease in	34
coronavirus isolated from a	34
may be due to	34
interferon beta against mers	34
coronavirus neutralizing antibodies in	34
remdesivir and combination lopinavir	34
causes transient lower respiratory	34
the emergence of mers	34
a public health emergency	34
at the beginning of	34
of mers coronavirus from	34
as shown in table	34
novel coronavirus in the	34
three camel coronavirus species	34
it is difficult to	34
review of the literature	34
aspects and outcomes of	34
cells were transfected with	34
efficacy of remdesivir and	34
coronavirus outbreak in the	34
and interferon beta against	34
is an urgent need	34
respiratory syndrome coronavirus from	34
the importance of the	34
coronavirus species and recombination	34
tract infection in rhesus	34
covs in saudi arabia	34
of remdesivir and combination	34
in any of the	34
of three camel coronavirus	34
have also been reported	34
of the viral genome	34
born to mothers with	34
severe acute respiratory infection	34
a h n virus	34
clinical aspects and outcomes	34
infected pneumonia in wuhan	34
been reported to be	34
prevalence of middle east	34
respiratory syndrome corona virus	34
and recombination of mers	34
camel coronavirus species and	34
the outbreak of sars	34
the virus in the	34
the causative agent of	34
isolation of mers coronavirus	34
converting enzyme is a	34
species and recombination of	34
a report of cases	33
early transmission dynamics in	33
basis of binding between	33
and risk factors for	33
dromedary camels in egypt	33
and its receptor cd	33
are summarized in table	33
familial cluster of pneumonia	33
as one of the	33
pneumonia associated with the	33
a broad spectrum of	33
the novel coronavirus indicating	33
uses the ace receptor	33
in a recent study	33
the highest number of	33
mechanism of action of	33
of the innate immune	33
related to the sars	33
mers coronaviruses in dromedary	33
the use of corticosteroids	33
be due to the	33
in response to the	33
the emergence of the	33
macaque model of mers	33
coronavirus infection and disease	33
acute respiratory syndrome and	33
disease prevention and control	33
of pneumonia associated with	33
structural and accessory proteins	33
the national institutes of	33
the transmission of mers	33
a familial cluster of	33
study of a family	33
a single dose of	33
was added to the	33
transmission dynamics in wuhan	33
testing for middle east	33
a key role in	33
parts of the world	33
was used as the	33
comparative therapeutic efficacy of	33
be explained by the	33
was used as a	33
circulation of three camel	33
a study of a	33
the s protein is	33
molecular basis of binding	33
was approved by the	33
imported case of middle	33
cluster of pneumonia associated	33
rhesus macaque model of	33
and approved the final	32
inhibits both epidemic and	32
was not associated with	32
assays reveal a high	32
high prevalence of antibody	32
potential conflicts of interest	32
used for the treatment	32
of antibody in dromedary	32
type i interferon production	32
prevalence of antibody in	32
emergency of international concern	32
antibodies in saudi arabia	32
have been identified in	32
for patients with severe	32
replication in cell culture	32
severity of the disease	32
has been found to	32
presence of middle east	32
mortality in patients with	32
the treatment of patients	32
of the immune response	32
coronavirus antibodies in saudi	32
entry into the host	32
reveal a high prevalence	32
protein of middle east	32
seroepidemiology for mers coronavirus	32
high morbidity and mortality	32
in the s protein	32
is likely to be	32
spread of the disease	32
or in combination with	32
cellular immune responses in	32
first case of novel	32
the s and s	32
can be found in	32
cov and its receptor	32
antibody in dromedary camels	32
severe respiratory illness caused	32
is mediated by the	32
of binding between novel	32
in jeddah and riyadh	32
similar to those of	32
binding between novel human	32
between novel human coronavirus	32
it has been shown	32
reported to the world	32
we would like to	32
infection control and prevention	32
both epidemic and zoonotic	32
epidemic and zoonotic coronaviruses	32
in dromedary camel herd	32
would like to thank	32
for mers coronavirus using	32
of a new human	32
type i and type	32
mers outbreak in south	31
number of confirmed cases	31
investigation middle east respiratory	31
syndrome coronavirus in bat	31
in the prefusion conformation	31
related viruses in bats	31
characterization of a bat	31
relative of human middle	31
were included in the	31
mers coronavirus using microneutralisation	31
the national institute of	31
are likely to be	31
close relative of human	31
the presence or absence	31
safety and immunogenicity of	31
virus was detected in	31
an outbreak of middle	31
that uses the ace	31
the epidemiology of mers	31
therapy for critically ill	31
identification and characterization of	31
microneutralisation and pseudoparticle virus	31
is associated with a	31
health emergency of international	31
causes lethal pneumonia in	31
for sars and mers	31
coronavirus using microneutralisation and	31
a descriptive genomic study	31
infection middle east respiratory	31
the emergence of sars	31
a randomized clinical trial	31
the basis of the	31
using microneutralisation and pseudoparticle	31
a possible cause of	31
transmissibility of middle east	31
to be the most	31
for the study of	31
the central nervous system	31
respiratory syndrome coronavirus pneumonia	31
as well as a	31
respiratory syndrome coronavirus mers	31
of a bat sars	31
coronavirus that uses the	31
these results indicate that	31
the rhesus macaque model	31
in this study were	31
prevention and control measures	31
public health emergency of	31
this study was to	31
of the risk of	31
there was no significant	31
upper respiratory tract infections	31
at a concentration of	31
center experience in saudi	31
days after symptom onset	31
in the course of	31
and pseudoparticle virus neutralisation	30
was first identified in	30
the results showed that	30
allergy and infectious diseases	30
cells were infected with	30
in the rhesus macaque	30
it has also been	30
virus neutralisation assays reveal	30
neutralisation assays reveal a	30
humoral and cellular immune	30
lethal pneumonia in the	30
pneumonia in the common	30
and evolution of pathogenic	30
min at room temperature	30
livestock in saudi arabia	30
in the early stage	30
respiratory syndrome in a	30
international severe acute respiratory	30
like coronavirus that uses	30
uenza a h n	30
days after the onset	30
evolution of pathogenic coronaviruses	30
as a possible cause	30
in vitro antiviral activity	30
treatment of patients with	30
for disease prevention and	30
a descriptive study clinical	30
of angiotensin converting enzyme	30
the outbreak of mers	30
infl uenza a h	30
to the fact that	30
these findings suggest that	30
coronavirus as a possible	30
the majority of the	30
of allergy and infectious	30
of mers and sars	30
better understanding of the	30
possible cause of severe	30
lower respiratory tract infections	30
mers coronavirus from a	30
and phylogenetic analysis of	30
pseudoparticle virus neutralisation assays	30
coronavirus from a dromedary	30
a mouse model of	30
respiratory syndrome coronavirus fusion	30
closely related to the	30
of inflammatory cytokines and	30
cov causes lethal pneumonia	30
the outbreak in the	30
mers outbreak in the	30
the origin of the	30
be one of the	30
have no competing interests	29
respiratory syndrome coronavirus the	29
been found to be	29
activation of the spike	29
is responsible for the	29
has been detected in	29
with human receptor dpp	29
to the development of	29
at the university of	29
emergence of a novel	29
upper respiratory tract and	29
host cell entry of	29
a combination of lopinavir	29
human neutralizing monoclonal antibodies	29
coronavirus in the united	29
and characterization of viruses	29
of emerging infectious diseases	29
on the arabian peninsula	29
respiratory tract infections in	29
of viruses related to	29
domestic livestock in saudi	29
monoclonal antibody against mers	29
coronavirus replication in cell	29
of proinflammatory cytokines and	29
domain complexed with human	29
domain of the spike	29
an intensive care unit	29
patients with severe mers	29
were observed in the	29
complexed with human receptor	29
prevent the spread of	29
and the risk of	29
structural basis for the	29
of lopinavir ritonavir in	29
of the number of	29
to the emergence of	29
a major role in	29
the innate immune system	29
into the host cell	29
novel coronavirus indicating person	29
seroprevalence in domestic livestock	29
in domestic livestock in	29
risk factors for primary	29
they have no competing	29
alone or in combination	29
n and h n	29
increase in the number	29
the spread of covid	29
h n and h	29
declare no conflict of	29
exposure in an emergency	29
from middle east respiratory	29
virus in chinese horseshoe	29
the institutional review board	29
and clinical features of	28
epidemiology of middle east	28
primary middle east respiratory	28
and the pathogenesis of	28
centre for disease prevention	28
during the outbreak of	28
from animals in southern	28
those who did not	28
authors declare no conflict	28
are shown in table	28
single patient exposure in	28
risk factors for middle	28
the sars coronavirus spike	28
of transmission of mers	28
type i and ii	28
confirmed cases of middle	28
in health care workers	28
entry of middle east	28
interferon therapy in patients	28
the sars coronavirus from	28
estimation of pandemic risk	28
prophylactic and therapeutic remdesivir	28
characterization of viruses related	28
coronavirus seroprevalence in domestic	28
european centre for disease	28
and interferon therapy in	28
sars coronavirus from animals	28
replication by a combination	28
animals in southern china	28
a single patient exposure	28
has been shown that	28
patient exposure in an	28
syndrome coronavirus spike glycoprotein	28
coronavirus open reading frame	28
reduces virus excretion after	28
an ic value of	28
therapy in patients infected	28
virus excretion after mers	28
systematic review of treatment	28
coronavirus disease in china	28
has not yet been	28
as compared to the	28
humanized mouse model of	28
were infected with mers	28
coronavirus replication by a	28
viruses related to the	28
to the sars coronavirus	28
of the incubation period	28
more likely to have	28
following a single patient	28
has been used to	28
to the arabian peninsula	28
the transmission of the	28
coronavirus from animals in	28
in saudi arabia mers	28
highly pathogenic avian influenza	28
factors for middle east	28
studies are required to	28
for primary middle east	28
threat to public health	28
vaccine reduces virus excretion	28
risk factors for mortality	28
with respect to the	28
the risk factors for	28
interhuman transmissibility of middle	28
infected with the middle	28
outbreak of novel coronavirus	28
the mechanism of action	28
prevention and control of	28
the pathogenesis of mers	28
syndrome coronavirus infection during	28
factors for primary middle	28
hospitalized patients with covid	27
in the emergency room	27
in view of the	27
the ability of the	27
be used as a	27
of personal protective equipment	27
national institute of allergy	27
and the presence of	27
the average number of	27
east respiratory syndrome middle	27
was no significant difference	27
in contrast to the	27
respiratory syndrome coronavirus during	27
pregnant women with covid	27
syndrome coronavirus replication in	27
as the number of	27
syndrome coronavirus as a	27
there have been no	27
of fully human antibodies	27
epithelial cells of the	27
institute of allergy and	27
cov infection in the	27
national health commission of	27
serology in major livestock	27
innate immune response to	27
also known as cd	27
a high mortality rate	27
the viral spike protein	27
were found to have	27
efficacy of fully human	27
h n influenza a	27
livestock species in an	27
major livestock species in	27
reverse transcription polymerase chain	27
patients with acute respiratory	27
of their replication and	27
lower respiratory tract specimens	27
chronic obstructive pulmonary disease	27
cd t cells in	27
the inhibitory activity of	27
like virus in chinese	27
is a potent inhibitor	27
a review of the	27
mice infected with mers	27
study of hospitalized patients	27
an affected region in	27
pregnant women infected with	27
in hospitalized patients with	27
and acute respiratory distress	27
in an affected region	27
has been associated with	27
into the host cells	27
against severe acute respiratory	27
of acute respiratory distress	27
there is a need	27
on the cell surface	27
ncov spike in the	27
characteristics of coronavirus disease	27
review of treatment effects	27
novel humanized mouse model	27
with sars and mers	27
spike in the prefusion	27
progression to respiratory failure	27
the emerging novel human	27
the interaction between the	27
clinical characteristics of coronavirus	27
to the intensive care	27
a novel humanized mouse	27
affected region in jordan	27
in a novel humanized	27
rift valley fever virus	27
in an emergency room	27
species in an affected	27
tertiary care hospital in	27
of health and welfare	27
specific human monoclonal antibody	27
in major livestock species	27
mers coronavirus neutralizing antibodies	27
report of cases from	27
in dromedary camels middle	27
viral shedding and antibody	27
and antibody response in	26
little is known about	26
with a case fatality	26
in the human respiratory	26
infected with middle east	26
we found that the	26
an overview of their	26
syndrome coronavirus fusion inhibitor	26
their replication and pathogenesis	26
ultrastructural findings of a	26
respiratory syncytial virus infection	26
a new human coronavirus	26
are not susceptible to	26
a critical role in	26
the immune response to	26
tract of inoculated dromedary	26
human antibodies against spike	26
compared to those of	26
geographic distribution of mers	26
postexposure efficacy of fully	26
and adaptive immune responses	26
had a history of	26
severe acute respiratory illness	26
emergence of middle east	26
antibody response in patients	26
overview of their replication	26
of the disease in	26
was associated with a	26
cov outbreak following a	26
in the early stages	26
the functional receptor for	26
entry into target cells	26
been reported to the	26
an epidemiological outbreak study	26
cases in saudi arabia	26
this is the first	26
pathological findings of covid	26
a transgenic mouse model	26
cells were washed with	26
the chinese center for	26
of an outbreak of	26
early stage of the	26
is shown in fig	26
are potent inhibitors of	26
may be related to	26
no significant difference in	26
protein in a novel	26
of human coronavirus nl	26
receptor binding domain of	26
viral replication in the	26
is thought to be	26
of the spike glycoprotein	26
have been used to	26
spike protein in a	26
the detection of mers	26
the majority of cases	26
lopinavir ritonavir in the	26
against spike protein in	26
outbreak following a single	26
a median of days	26
the cells were washed	26
peripheral blood mononuclear cells	26
an increased risk of	26
clinical signs of disease	26
for treatment of covid	26
severe acute respiratory and	26
antibodies against spike protein	26
of inoculated dromedary camels	26
characterization of the novel	26
for min at room	26
is considered to be	26
these data suggest that	26
transcriptase polymerase chain reaction	26
prevention and treatment of	26
in the united kingdom	26
s f cd l	26
fully human antibodies against	26
of coronavirus spike proteins	26
are considered to be	26
respiratory tract of inoculated	26
in combination with other	26
shedding and antibody response	26
the novel human coronavirus	26
the development of vaccines	26
the use of a	26
respiratory distress syndrome and	26
of viral shedding and	26
findings of a fatal	26
in line with the	25
time reverse transcription pcr	25
emergency room in south	25
functional receptor for sars	25
confirmed cases and deaths	25
on the number of	25
the sars outbreak in	25
emerg infect dis doi	25
the humoral immune response	25
of lopinavir ritonavir and	25
mers coronavirus infection in	25
mediated activation of the	25
preliminary epidemiological assessment of	25
with atypical pneumonia after	25
acute respiratory syndrome the	25
syndrome coronavirus as an	25
as part of the	25
laboratory testing for middle	25
declare no competing interests	25
the number of infected	25
in terms of the	25
a patient with atypical	25
in an animal model	25
early phase of the	25
does not result in	25
pneumonia after visiting wuhan	25
of the arabian peninsula	25
genomic characterization of the	25
the s proteins of	25
was observed in the	25
the replication of sars	25
in health care settings	25
epidemiological assessment of mers	25
the novel coronavirus from	25
alphacoronavirus and betacoronavirus and	25
ritonavir in the treatment	25
induction of inflammatory cytokines	25
respiratory syndrome coronavirus entry	25
than that of sars	25
in adults hospitalized with	25
convalescent plasma therapy in	25
of human coronavirus oc	25
the structure of the	25
mers coronavirus among dromedary	25
coronavirus in jeddah and	25
article can be found	25
south korea middle east	25
in a study of	25
of the disease and	25
ill patients with covid	25
to be effective against	25
identified in saudi arabia	25
and the cells were	25
novel human betacoronavirus c	25
made available under a	25
it is unclear whether	25
transgenic mice infected with	25
d g and i	25
stability of middle east	25
by the severe acute	25
high case fatality rate	25
novel human coronavirus emc	25
by human monoclonal antibodies	25
study of outbreaks of	25
the case of the	25
in the range of	25
fatal case of middle	25
the species severe acute	25
coronavirus among dromedary camels	25
in the majority of	25
transmission characteristics of mers	25
of mers coronavirus among	25
emerging middle east respiratory	25
the absence of a	25
room in south korea	25
this article can be	25
cells were incubated with	25
virus isolated from the	25
outside the middle east	25
a wide variety of	25
and the development of	25
species severe acute respiratory	25
discovery of a novel	25
an emergency room in	25
avian infectious bronchitis virus	25
atypical pneumonia after visiting	25
patient with atypical pneumonia	25
and the use of	25
was not detected in	25
animal model of mers	25
immune responses in mice	25
distribution of mers coronavirus	25
g and i t	25
acute respiratory and emerging	25
from bench to bedside	25
in vitro activity against	24
hospitalized with severe covid	24
number of secondary cases	24
and naming it sars	24
in the general population	24
identification of a new	24
were detected in the	24
the genus deltacoronavirus supports	24
combination with ribavirin to	24
regard to jurisdictional claims	24
mammalian and avian coronaviruses	24
human to human transmission	24
human monoclonal antibody protects	24
by the novel coronavirus	24
cell entry of middle	24
on middle east respiratory	24
gene source of gammacoronavirus	24
the control of the	24
were similar to those	24
plays a role in	24
east respiratory syndrome corona	24
management of patients with	24
the rest of the	24
have been reported from	24
was used for the	24
genus deltacoronavirus supports bat	24
risk factors for mers	24
virological and clinical findings	24
and chemokines in human	24
initial virological and clinical	24
effectiveness of convalescent plasma	24
the risk of death	24
in a single inoculum	24
and avian coronaviruses in	24
adults hospitalized with severe	24
was not certified by	24
a result of the	24
not certified by peer	24
source of gammacoronavirus and	24
course of the disease	24
syndrome coronavirus in jeddah	24
is important to note	24
in the intensive care	24
and ultrastructural findings of	24
a major outbreak of	24
a severe acute respiratory	24
to jurisdictional claims in	24
jurisdictional claims in published	24
are involved in the	24
are similar to those	24
by the fact that	24
dromedary camels in the	24
lower respiratory tract of	24
sars in the healthcare	24
with severe disease and	24
is made available under	24
treatment in the rhesus	24
based vaccine reduces virus	24
neutral with regard to	24
seven novel mammalian and	24
an urgent need for	24
was shown to be	24
ribavirin to treat middle	24
characteristics of mers and	24
is strongly inhibited by	24
of porcine epidemic diarrhea	24
of the cases were	24
avian coronaviruses in the	24
feline infectious peritonitis virus	24
phase i clinical trial	24
entry of the virus	24
outbreak investigation middle east	24
gene source of alphacoronavirus	24
used in the treatment	24
remains neutral with regard	24
mers and sars in	24
it is made available	24
is based on the	24
of outbreaks of middle	24
another zoonotic betacoronavirus causing	24
to sars and mers	24
and betacoronavirus and avian	24
the extent of the	24
certified by peer review	24
with regard to jurisdictional	24
the safety and efficacy	24
ncov and naming it	24
human bronchial epithelial cells	24
respiratory disease in humans	24
of seven novel mammalian	24
treat middle east respiratory	24
novel mammalian and avian	24
source of alphacoronavirus and	24
coronaviruses in the genus	24
an outbreak investigation middle	24
the median incubation period	24
in the early phase	24
of alphacoronavirus and betacoronavirus	24
which was not certified	24
of the international committee	24
the aim of this	24
can be used as	24
with ribavirin to treat	24
outside the arabian peninsula	24
patients with confirmed mers	24
the presence of a	24
in the genus deltacoronavirus	24
the h n influenza	24
recombinant modified vaccinia virus	24
pathogenic coronavirus isolated from	24
human immunodeficiency virus type	24
there is no specific	24
infections in health care	24
control study of hospitalized	24
coronavirus infectious bronchitis virus	24
to treat middle east	24
and sars in the	24
cov cl pro and	24
the presence of viral	24
severe disease and death	24
it is likely that	23
role of lopinavir ritonavir	23
associated middle east respiratory	23
in the regulation of	23
chemokines in human macrophages	23
in published maps and	23
is a type i	23
the onset of the	23
the structural and accessory	23
avian coronaviruses as the	23
s subunit of the	23
in this study was	23
severe in vitro cytopathology	23
deltacoronavirus supports bat coronaviruses	23
an animal model of	23
approved the final manuscript	23
in mice infected with	23
neutralizing antibodies in camels	23
rna was extracted from	23
induces severe in vitro	23
betacoronavirus and avian coronaviruses	23
with fetal bovine serum	23
supports bat coronaviruses as	23
at the level of	23
aberrant induction of inflammatory	23
inhibits the replication of	23
of the virus from	23
guidance for the public	23
mers in south korea	23
and public health authorities	23
reverse transcriptase polymerase chain	23
approved by the institutional	23
the number of confirmed	23
has the potential to	23
and avian coronaviruses as	23
the one health concept	23
avian influenza a h	23
coronavirus illness in humans	23
outcomes of middle east	23
a high level of	23
of sars coronavirus infection	23
important to note that	23
of novel coronavirus infections	23
for the novel coronavirus	23
upper respiratory tract infection	23
has yet to be	23
coronavirus infection middle east	23
no conflicts of interest	23
vitro cytopathology and is	23
syndrome coronavirus illness in	23
for up to days	23
animal care and use	23
a hospital outbreak of	23
transmission and evolution of	23
nature remains neutral with	23
and the role of	23
to be able to	23
the number of mers	23
compared to the control	23
the antiviral effects of	23
specific cd t cells	23
the s domain of	23
alpha b and ribavirin	23
genome sequence of a	23
maps and institutional affiliations	23
and is strongly inhibited	23
than that of the	23
cytopathology and is strongly	23
study was approved by	23
with a history of	23
syndrome coronavirus after two	23
discovery of seven novel	23
zoonotic betacoronavirus causing sars	23
with a mortality rate	23
distributed under the terms	23
it is believed that	23
implications for the origin	23
and outcomes of middle	23
the surface of the	23
bat coronaviruses as the	23
respiratory syndrome coronavirus illness	23
the origin of sars	23
ill patients with mers	23
in the setting of	23
and aberrant induction of	23
published maps and institutional	23
the development of an	23
major outbreak of severe	23
claims in published maps	23
the case of mers	23
screening of an fda	23
countries in the middle	23
us centers for disease	23
the absence of any	23
respiratory and emerging infection	23
replication induces severe in	23
was estimated to be	23
and their role in	23
springer nature remains neutral	23
coronavirus replication induces severe	23
such as severe acute	23
an incubation period of	23
a in combination with	23
of a transgenic mouse	23
a limited number of	23
for the evaluation of	23
in vitro cytopathology and	23
new insights into the	23
a small number of	22
on sars and mers	22
betacoronavirus lineage c viruses	22
and innate immune responses	22
human cases of mers	22
was identified as the	22
the duration of the	22
a trial of lopinavir	22
of gammacoronavirus and deltacoronavirus	22
risk factors associated with	22
can be divided into	22
of acute respiratory infections	22
of the first mers	22
factors influencing disaster response	22
the efficacy of the	22
the identification of the	22
inhibition of middle east	22
of human coronavirus e	22
and treatment of covid	22
a retrospective review of	22
cyclosporin a or interferon	22
strongly inhibited by cyclosporin	22
a community outbreak of	22
this preprint this version	22
the results of this	22
studies have demonstrated that	22
by the presence of	22
number of cases in	22
as a model for	22
organ infection and the	22
serological study middle east	22
were negative for mers	22
viral loads in the	22
authors declare no competing	22
with a range of	22
for the origin of	22
cells infected with mers	22
respiratory syndrome coronavirus after	22
at increased risk of	22
in the sera of	22
at high risk of	22
of the fusion core	22
the spike protein gene	22
in comparison to the	22
the large number of	22
acute middle east respiratory	22
contact with dromedary camels	22
combination of lopinavir ritonavir	22
the phylogenetic tree of	22
the genome sequence of	22
of the host immune	22
based study of outbreaks	22
with the development of	22
drugs for treatment of	22
coronavirus infection in humans	22
sequence of a novel	22
to the best of	22
and guidance for the	22
as soon as possible	22
preprint this version posted	22
and viral load in	22
in dromedary camels and	22
infection of rhesus macaques	22
potent inhibitor of sars	22
results showed that the	22
it has been demonstrated	22
that can be used	22
been shown to inhibit	22
the epidemiological characteristics of	22
unrecognized asymptomatic or mild	22
inhibited by cyclosporin a	22
and emerging infection consortium	22
cov pl pro was	22
coronavirus spike protein by	22
and reviewed the manuscript	22
by cyclosporin a or	22
the time of the	22
a human monoclonal antibody	22
multiple organ infection and	22
of west nile virus	22
a potential target for	22
the emerging middle east	22
for this preprint this	22
report of two cases	22
inhibits type i interferon	22
structural studies of sars	22
care and use committee	22
a risk factor for	22
length infectious cdna of	22
that there is a	22
transgenic mouse model of	22
from symptom onset to	22
samples were collected from	22
has been demonstrated that	22
of the creative commons	22
in patients with coronavirus	22
early stages of the	22
is known about the	22
for h at c	22
the creative commons attribution	22
a vital role in	22
the development of novel	22
to evaluate the efficacy	22
a total of laboratory	22
s and s subunits	22
spike protein of the	22
between the two groups	22
infection and the pathogenesis	22
license it is made	21
implications for pathogenesis and	21
kinetic analysis of viral	21
global alert and response	21
in dromedary camels from	21
epidemiological findings from a	21
in saudi arabia the	21
of the index patient	21
have been identified as	21
were approved by the	21
spectrum of disease severity	21
severe acute respiratory distress	21
the most common symptoms	21
shedding and immunological responses	21
analysis of viral shedding	21
infection in south korea	21
the life cycle of	21
syndrome is associated with	21
a tertiary care hospital	21
asymptomatic or mild case	21
syndrome coronavirus through its	21
coronavirus infections related to	21
findings from a retrospective	21
sea urchin egg homogenate	21
sars coronavirus spike protein	21
human respiratory disease in	21
novel coronavirus from wuhan	21
mortality risk factors for	21
of the extent of	21
load in a community	21
the lungs of the	21
of rift valley fever	21
in sars and mers	21
an overview of the	21
the molecular biology of	21
care and use of	21
the development of new	21
human and camel mers	21
in the face of	21
a multiplicity of infection	21
representing a broad spectrum	21
lopinavir ritonavir and interferon	21
to prevent the spread	21
from a retrospective investigation	21
is known to be	21
of the novel middle	21
s in supplementary material	21
infections related to a	21
bats are natural reservoirs	21
detection of novel coronavirus	21
immunological responses in mers	21
of science and technology	21
reduce the risk of	21
it is known that	21
host species restriction of	21
mers patients representing a	21
the potential risk of	21
from camels to humans	21
likely unrecognized asymptomatic or	21
in south korea in	21
in agreement with the	21
ritonavir in adults hospitalized	21
to a lesser extent	21
in a community outbreak	21
both in vitro and	21
is associated with the	21
patients representing a broad	21
for the use of	21
to acute respiratory distress	21
analyses were performed using	21
acute respiratory syndrome among	21
of the first imported	21
a likely unrecognized asymptomatic	21
analysis based on decade	21
active replication of middle	21
related to a likely	21
read and approved the	21
the use of convalescent	21
incubated for h at	21
with an ic value	21
detection of middle east	21
and kinetic analysis of	21
viral load in a	21
coronavirus through its receptor	21
also been shown to	21
due to the high	21
in south korea and	21
cov nsp and nsp	21
comparative and kinetic analysis	21
species restriction of middle	21
sars coronavirus infection and	21
respiratory syndrome coronavirus through	21
progression and viral load	21
the viral polymerase and	21
an analysis based on	21
it was shown that	21
the middle east region	21
clinical progression and viral	21
performed as previously described	21
to a likely unrecognized	21
structure of the sars	21
spike glycoprotein of the	21
international license it is	21
a and b viruses	21
generation of a transgenic	21
van doremalen et al	21
immunopathology on challenge with	21
admission to the icu	21
broad spectrum of disease	21
syndrome coronavirus and aberrant	21
or acute respiratory distress	21
long structural studies of	21
the effect of the	21
of the respiratory tract	21
and immunological responses in	21
for the diagnosis of	21
risk of transmission of	21
care hospital in saudi	21
syndrome coronavirus infections related	21
there are currently no	21
coronavirus and aberrant induction	21
a significant role in	21
of probable sars cases	21
higher than that of	21
in the past years	21
in light of the	21
management of severe acute	21
the analysis of the	21
responses in mers patients	21
summary and literature update	21
restriction of middle east	21
more than half of	21
were shown to be	21
have been exposed to	21
polymerase chain reaction assays	21
in acute respiratory distress	21
the host immune system	21
in mers patients representing	21
in a previous study	21
viral shedding and immunological	21
isolated from the human	20
the upper and lower	20
the past two decades	20
of the importance of	20
during the study period	20
serum samples from the	20
respiratory disease in china	20
dromedary camels are the	20
as well as other	20
from the first imported	20
protein of pipistrellus bat	20
dromedary camels to humans	20
new coronavirus associated with	20
of coronaviruses in bats	20
viruses from patients with	20
of the new coronavirus	20
respiratory syndrome isolation of	20
are natural reservoirs of	20
the active site of	20
a case report of	20
acute respiratory infections in	20
the reciprocal of the	20
the median age of	20
of human isolates revealed	20
of pregnant women with	20
induced acute respiratory distress	20
therapeutic options for middle	20
with human respiratory disease	20
a cluster of cases	20
a recent study showed	20
in human airway epithelial	20
c viruses in bats	20
syndrome coronavirus infection middle	20
patients infected with mers	20
respiratory syndrome coronavirus open	20
the best of our	20
cultured from dromedary camels	20
associated with human respiratory	20
rhesus macaques with mers	20
and complete genome sequence	20
and the proofreading exoribonuclease	20
are shown in fig	20
by the addition of	20
deaths have been reported	20
bat coronavirus hku in	20
spike protein of pipistrellus	20
analysis and virus cultured	20
of the upper respiratory	20
further studies are needed	20
comparative serological study middle	20
as middle east respiratory	20
of pipistrellus bat coronavirus	20
lower than that of	20
a new coronavirus associated	20
information on the epidemiology	20
and is targeted by	20
has been suggested that	20
may be associated with	20
the viral spike glycoprotein	20
syndrome coronavirus open reading	20
syndrome coronavirus and the	20
the coronavirus spike protein	20
neonates born to mothers	20
to the use of	20
treatment of novel coronavirus	20
was isolated from a	20
the limit of detection	20
marked sequence divergence in	20
an essential role in	20
quasispecies that include homologues	20
mice transgenic for human	20
rhesus macaques and common	20
coronavirus hku in japanese	20
antivirals for the emerging	20
recent study showed that	20
a large tertiary care	20
of h n influenza	20
in patients with acute	20
was similar to that	20
presence of viral rna	20
the clinical course of	20
of convalescent plasma and	20
genetics with a full	20
is due to the	20
a prospective descriptive study	20
acute respiratory infections of	20
include homologues of human	20
as a receptor for	20
infection is associated with	20
review of medical records	20
homologues of human isolates	20
it was reported that	20
severe lower respiratory tract	20
influenza other respir viruses	20
proinflammatory cytokines and chemokines	20
it is noteworthy that	20
upe and orf a	20
of the s glycoprotein	20
is related to the	20
at a dose of	20
of rhesus macaques with	20
human isolates revealed through	20
viral shedding in mers	20
and the united states	20
an update on the	20
of a series of	20
by the viral polymerase	20
characterization and complete genome	20
spectrum antivirals for the	20
corticosteroid therapy for critically	20
hku in japanese pipistrelle	20
the activation of the	20
syndrome coronavirus by human	20
virus cultured from dromedary	20
in the current study	20
syndrome coronavirus quasispecies that	20
in an attempt to	20
viral polymerase and the	20
at a multiplicity of	20
under different environmental conditions	20
supplemented with fetal bovine	20
divergence in the spike	20
macaques and common marmosets	20
authors would like to	20
a pivotal role in	20
syndrome isolation of a	20
not included in the	20
the south korean outbreak	20
compound library identifies four	20
h n avian influenza	20
from the human respiratory	20
approved compound library identifies	20
options for middle east	20
for the spread of	20
patients with severe disease	20
of type i interferon	20
and viral shedding in	20
the n protein of	20
sequence divergence in the	20
respiratory syndrome coronavirus quasispecies	20
predictive factors for pneumonia	20
hospitalized patients with middle	20
can be used for	20
and virus cultured from	20
have not yet been	20
respiratory infections of viral	20
humans and dromedary camels	20
targeted by neutralizing antibodies	20
polymerase and the proofreading	20
coronavirus associated with human	20
that include homologues of	20
east respiratory syndrome coronaviruses	20
patients with the middle	20
of the host cell	20
lineage c viruses in	20
prevention and control guidelines	20
direct or indirect contact	20
had no role in	20
reverse genetics with a	20
the impact of the	20
reported from saudi arabia	20
in the field of	20
was found to have	20
respiratory syndrome is associated	20
play important roles in	20
coronavirus quasispecies that include	20
replication in the lungs	20
origin of the novel	20
for the emerging middle	20
evaluate the efficacy of	20
of type i ifn	20
none of the studies	19
neutralization of middle east	19
women with severe acute	19
and antigenicity of the	19
of candidate vaccine approaches	19
coronavirus susceptibility to the	19
novel coronavirus infection in	19
updated information on the	19
to the united states	19
were tested for mers	19
library identifies four small	19
systematic review and exploratory	19
dysregulated type i interferon	19
a crucial role in	19
new virus isolated from	19
and progression to respiratory	19
the quality of the	19
lessons from the coronavirus	19
characterization of betacoronavirus lineage	19
a potential source of	19
pneumonia development and progression	19
for the prevention and	19
in the formation of	19
has been observed in	19
evaluation of candidate vaccine	19
influenza a virus infection	19
as well as their	19
vaccine approaches for mers	19
been reported in the	19
the risk of transmission	19
exceptionally potent neutralization of	19
the epithelial cells of	19
for the generation of	19
natural reservoirs of sars	19
third week of illness	19
clinically developed drugs for	19
animal models for sars	19
genetic characterization of betacoronavirus	19
as a treatment of	19
which is consistent with	19
the prevention of human	19
best of our knowledge	19
of betacoronavirus lineage c	19
with the index patient	19
was first isolated in	19
a new virus isolated	19
sequencing and phylogenetic analysis	19
coronavirus by human monoclonal	19
shedding in mers patients	19
at high risk for	19
to the antiviral remdesivir	19
induction of proinflammatory cytokines	19
respiratory disease associated with	19
from the coronavirus disease	19
history of contact with	19
for the management of	19
the time of writing	19
occurred in saudi arabia	19
use of mechanical ventilation	19
syndrome coronavirus infection clinical	19
of respiratory syncytial virus	19
nasal and throat swabs	19
as well as to	19
in vitro inhibition of	19
the detection of sars	19
be used for the	19
of clinically developed drugs	19
mouse model for mers	19
at an moi of	19
molecule inhibitors of middle	19
of innate antiviral response	19
the international health regulations	19
coronavirus infections in health	19
transmission of severe acute	19
the discovery of the	19
cases with onset of	19
for hospitalized patients with	19
in the near future	19
the risk of infection	19
i and ii pneumocytes	19
potent neutralization of middle	19
important lessons from the	19
cd t cell responses	19
of avian influenza a	19
the use of ribavirin	19
at the plasma membrane	19
chain reaction assays for	19
plasma and hyperimmune immunoglobulin	19
the authors would like	19
article distributed under the	19
the outbreak in south	19
the novel coronavirus disease	19
chloroquine is a potent	19
to the control group	19
hyperimmune immunoglobulin for the	19
an increase in the	19
cytokine storm and immunopathology	19
of cytokine storm and	19
transmembrane serine protease tmprss	19
the natural reservoir of	19
cd t cells and	19
to the host cell	19
is targeted by neutralizing	19
it has been suggested	19
prophylactic and postexposure efficacy	19
and hyperimmune immunoglobulin for	19
characteristics of and important	19
syndrome severe acute respiratory	19
potential for human emergence	19
type i interferon and	19
recommendations for hospitalized patients	19
was admitted to the	19
with the severe acute	19
of hepatitis c virus	19
environmental contamination and viral	19
clinical management of severe	19
respiratory syndrome coronavirus nsp	19
n influenza a virus	19
repurposing of clinically developed	19
acute respiratory syndrome a	19
discovery of middle east	19
detection of severe acute	19
the first time in	19
infections of viral etiology	19
and important lessons from	19
h at room temperature	19
type i ifn production	19
was obtained from the	19
respiratory syndrome coronavirus causes	19
coronavirus spike protein and	19
from dromedary camels to	19
the decision to submit	19
factors for pneumonia development	19
dependent rna polymerase from	19
a first step in	19
the mode of transmission	19
has also been shown	19
inhibitor of sars coronavirus	19
in relation to the	19
over the course of	19
extent of the epidemic	19
i interferon production by	19
consequences of cytokine storm	19
be attributed to the	19
of and important lessons	19
in the presence or	19
candidate vaccine approaches for	19
is associated with high	19
into the human population	19
cases were reported in	19
on the development of	19
an urgent need to	19
to those of the	19
was isolated from the	19
in comparison with the	19
to determine whether the	19
thought to be the	19
contamination and viral shedding	19
is caused by a	19
immunoglobulin for the treatment	19
the sars epidemic in	19
retrospective review of medical	19
patients in saudi arabia	19
from the lower respiratory	19
animals vaccinated with chadox	19
near the arabian peninsula	19
the disease caused by	19
acute respiratory syndrome sars	19
susceptibility to the antiviral	19
figure s in supplementary	19
have been found to	19
in the aftermath of	19
of cd t cells	19
causes and consequences of	19
the expression levels of	19
infectious virus was detected	19
transmission potential of covid	18
evolution of human coronavirus	18
and intrauterine vertical transmission	18
access article distributed under	18
mers coronavirus middle east	18
compared to that in	18
to the viral spike	18
collected according to local	18
have been observed in	18
screening for middle east	18
acid are potent inhibitors	18
the democratic republic of	18
of nsp and nsp	18
hydroxychloroquine and azithromycin as	18
investigations and implications for	18
of the most important	18
the first report of	18
of cases from the	18
lethal pneumonia in sars	18
in the control group	18
the spread of this	18
molecular biology of coronaviruses	18
the absence of the	18
the context of a	18
coronavirus accessory protein a	18
is supported by a	18
the rbd of the	18
south korea and china	18
of human bronchial epithelial	18
all authors contributed to	18
and incubated for h	18
the host cell membrane	18
local customs from dromedary	18
neutralizing antibodies in mice	18
from the chinese center	18
characterization of severe acute	18
closely related to sars	18
sars cases with onset	18
structure of the mers	18
antigenicity of the sars	18
and azithromycin as a	18
east respiratory syndrome and	18
has also been reported	18
the virus to the	18
healthcare worker and family	18
for each of the	18
bat coronaviruses shows potential	18
clinical characteristics and intrauterine	18
syndrome coronavirus m protein	18
coalition for epidemic preparedness	18
coronavirus infection and spread	18
to an intensive care	18
and other coronavirus infections	18
as a vaccine candidate	18
neutralizing monoclonal antibody specifically	18
was added to each	18
produced by infection of	18
ill patients with the	18
shows potential for human	18
is important for the	18
that the use of	18
intrauterine vertical transmission potential	18
was performed using a	18
during the h n	18
was performed using the	18
in a pregnant woman	18
in the s subunit	18
prevention and control recommendations	18
summary of a report	18
inhibit the replication of	18
of human immunodeficiency virus	18
for treatment of middle	18
human monoclonal antibody against	18
the emergence of a	18
mycophenolic acid are potent	18
one of the main	18
the emergence of new	18
monoclonal antibody specifically targeting	18
control the spread of	18
from severe acute respiratory	18
respiratory syndrome coronavirus orf	18
first cases of middle	18
the potential to be	18
in the production of	18
syndrome coronavirus in cell	18
of circulating bat coronaviruses	18
a treatment of covid	18
s protein of the	18
and mycophenolic acid are	18
in a tertiary hospital	18
monoclonal antibodies to the	18
characteristics and intrauterine vertical	18
clinical and laboratory findings	18
a safe and effective	18
shown in figure a	18
is similar to that	18
the korea centers for	18
and implications for the	18
respiratory syndrome coronavirus m	18
as a reservoir for	18
with onset of illness	18
suppression of innate antiviral	18
treated with a combination	18
infection in saudi arabia	18
cov spike protein induces	18
sars coronavirus infection in	18
was first isolated from	18
highlight the importance of	18
have no conflict of	18
lower respiratory tract disease	18
the rbd of mers	18
use of laboratory animals	18
cov s protein and	18
results of an open	18
at the s s	18
to local customs from	18
a significant increase in	18
further studies are required	18
preventing the spread of	18
in a number of	18
customs from dromedary camels	18
syndrome in a large	18
convalescent plasma and hyperimmune	18
genome sequence of the	18
respiratory syndrome coronavirus envelope	18
like cluster of circulating	18
developed drugs for treatment	18
of human coronavirus genomes	18
first step in understanding	18
the enzymatic activity of	18
cluster of circulating bat	18
a b and ribavirin	18
is part of the	18
according to local customs	18
a high rate of	18
under the control of	18
in mice transgenic for	18
virus entry and syncytia	18
human coronavirus in a	18
respiratory syndrome severe acute	18
the united states and	18
circulating bat coronaviruses shows	18
receptor for sars coronavirus	18
target for vaccine and	18
for vaccine and therapeutic	18
we were able to	18
the diagnosis and treatment	18
as well as for	18
innate antiviral response by	18
east respiratory syndrome is	18
composition and divergence of	18
evidence of middle east	18
was reported to be	18
the korean mers outbreak	18
of the murine coronavirus	18
features of the first	18
and use of laboratory	18
the characteristics of the	18
use of personal protective	18
implications for the prevention	18
control recommendations for hospitalized	18
to the presence of	18
for h at room	18
of modified endoplasmic reticulum	18
and control recommendations for	18
could be explained by	18
is estimated to be	18
in a biosafety level	18
in nine pregnant women	18
responses to mers coronavirus	18
the nucleocapsid protein of	18
molecular evolution of human	18
cov was detected in	18
and transmission of middle	18
among health care workers	18
vertical transmission potential of	18
coronaviruses shows potential for	18
of a report of	18
asymptomatic middle east respiratory	18
by the viral spike	18
hospital in south korea	18
are those of the	18
due to the fact	18
from bats to humans	18
s protein of mers	18
the third week of	18
can be activated by	18
a fatality rate of	18
and consequences of cytokine	18
was defined as the	18
review and exploratory meta	18
severe respiratory disease in	18
in milk collected according	18
milk collected according to	18
macrophages and dendritic cells	18
play a major role	18
were obtained from the	18
antibodies in milk collected	18
the nature of the	18
cases from the chinese	18
in a large tertiary	18
development and progression to	18
syndrome coronavirus envelope protein	18
and the lack of	18
the transmission of sars	18
is no evidence of	18
the viral life cycle	18
institutional review board of	18
infection in nine pregnant	18
were washed with pbs	18
are responsible for the	18
a higher risk of	18
risk factors of mers	18
in treatment of covid	18
dromedary camels and humans	18
an emerging infectious disease	18
neutralizing monoclonal antibodies to	18
when compared to the	18
potent inhibitors of middle	18
entry and syncytia formation	18
admitted to hospital with	18
association of higher mers	17
as an intermediate host	17
i and type iii	17
of the newly identified	17
convalescent plasma therapy for	17
genome analysis and virus	17
the purpose of this	17
responses cause lethal pneumonia	17
since the emergence of	17
clinical features of the	17
with ic values of	17
domain in middle east	17
a patient with severe	17
immune responses to the	17
novel coronavirus outbreak in	17
confirmed cases of covid	17
cells infected with sars	17
patients in hong kong	17
the rational design of	17
human betacoronavirus lineage c	17
of bat coronavirus hku	17
i interferon and inflammatory	17
by human neutralizing monoclonal	17
have contributed to the	17
east respiratory syndrome with	17
prevalence of comorbidities in	17
coronavirus infection in hospital	17
of bat coronaviruses in	17
rna and neutralising antibodies	17
respiratory syndrome coronavirus nucleocapsid	17
a humanized neutralizing antibody	17
network of modified endoplasmic	17
this version posted may	17
was also observed in	17
neutralising antibodies in milk	17
coronaviruses into the spotlight	17
coronavirus by characterization of	17
have shown that the	17
with a fatality rate	17
lineage c virus in	17
of human neutralizing antibodies	17
design of hydroxychloroquine for	17
viral rna in the	17
by characterization of a	17
activity and projection of	17
nucleocapsid proteins function as	17
in the emergence of	17
direct contact with the	17
the effectiveness of convalescent	17
and united arab emirates	17
results of this study	17
in human ex vivo	17
and their healthcare worker	17
were positive for mers	17
there was a statistically	17
in a macaque model	17
of the present study	17
cov by human neutralizing	17
coronavirus severe acute respiratory	17
date of symptom onset	17
protein inhibits type i	17
in the last years	17
and in vivo studies	17
was based on the	17
have been isolated from	17
health care workers in	17
end of the genome	17
there has been a	17
the extent to which	17
was considered statistically significant	17
antibodies to the viral	17
a conspecific virus from	17
influenza virus h n	17
our results showed that	17
by the end of	17
there is currently no	17
the entry of the	17
and projection of optimized	17
ebola virus disease therapeutics	17
type ii transmembrane serine	17
to mers coronavirus infection	17
study showed that the	17
characteristics of novel coronavirus	17
and neutralising antibodies in	17
and the need for	17
antiviral activity and projection	17
no reuse allowed without	17
and perinatal outcomes of	17
protein of the novel	17
hydroxychloroquine for the treatment	17
and nucleocapsid proteins function	17
first confirmed cases of	17
cases from saudi arabia	17
caused by the novel	17
function as interferon antagonists	17
distribution of ace protein	17
trial of ebola virus	17