trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
the presence of	549
as well as	470
the formation of	423
in order to	329
the plasma membrane	324
in the presence	289
of the membrane	276
one of the	262
of the protein	255
due to the	226
the effect of	224
the role of	209
structure of the	180
it has been	178
the use of	174
extracorporeal membrane oxygenation	170
based on the	167
the mechanism of	160
the development of	159
the interaction of	147
a number of	145
the host cell	144
the cell surface	138
the number of	135
in addition to	131
the case of	129
analysis of the	127
can be used	127
involved in the	127
changes in the	124
to study the	124
the structure of	123
of influenza virus	123
properties of the	123
the effects of	122
of the cell	121
in this study	120
on the other	120
in the membrane	120
the surface of	119
of the peptide	118
part of the	116
the lipid bilayer	115
of the fusion	115
been shown to	114
the cell membrane	112
in the case	111
to investigate the	111
well as the	110
understanding of the	109
in the absence	109
semliki forest virus	108
the other hand	108
hepatitis c virus	107
the absence of	107
a variety of	107
the golgi apparatus	105
of the viral	105
show that the	105
of the lipid	101
severe acute respiratory	100
formation of the	100
is required for	99
the binding of	98
by means of	97
the endoplasmic reticulum	96
found to be	95
as a result	95
has been shown	95
of the most	93
on the surface	93
be used to	93
in this work	93
the study of	92
of the two	91
the interaction between	90
acute respiratory syndrome	90
to determine the	90
in terms of	90
such as the	89
the influence of	89
molecular dynamics simulations	89
to be a	89
function of the	87
to the cell	87
associated with the	86
surface of the	86
role in the	85
are able to	84
the activity of	84
we show that	84
of the virus	84
to the membrane	83
that of the	83
shown to be	83
in which the	83
depending on the	83
we found that	82
have shown that	82
characterization of the	81
in response to	81
region of the	81
the fact that	81
a function of	80
a combination of	80
in contrast to	80
formation of a	80
of membrane proteins	79
interaction of the	78
the ability to	78
vesicular stomatitis virus	78
role of the	77
the kinetics of	77
with respect to	76
showed that the	76
was found to	76
the design of	75
amino acid residues	75
crystal structure of	75
in the cell	75
compared to the	75
are involved in	74
the fusion peptide	74
the ability of	73
found that the	73
an important role	73
is one of	73
was used to	72
it is possible	72
the rate of	72
as a function	72
and in the	72
there is a	71
respiratory syndrome coronavirus	70
to that of	70
related to the	70
the analysis of	69
has also been	69
the process of	69
the size of	68
as shown in	68
the cytoplasmic domain	67
that can be	67
across the membrane	67
the function of	67
of membrane fusion	67
a series of	67
is based on	67
have been used	66
suggest that the	65
important role in	65
interaction with the	65
is able to	65
shown in fig	65
the structure and	65
most of the	64
in living cells	64
of the host	63
the free energy	62
results show that	62
the regulation of	62
the importance of	62
to the plasma	62
the results of	62
and characterization of	62
can also be	62
with the membrane	61
some of the	61
of semliki forest	61
the amount of	61
wide range of	61
responsible for the	61
used as a	61
domain of the	61
the secretory pathway	60
atomic force microscopy	60
and function of	59
the fusion protein	59
activity of the	59
derived from the	59
to understand the	59
in the same	59
at the same	59
the production of	59
of the human	58
required for the	58
the site of	58
the dynamics of	57
a wide range	57
according to the	57
been used to	57
similar to that	56
shown that the	56
to interact with	56
the majority of	56
to the formation	56
the concentration of	56
present in the	56
of the golgi	56
the stability of	56
appear to be	56
studies on the	56
the addition of	56
effect of the	56
a range of	56
study of the	56
a and b	56
of the plasma	55
the treatment of	55
a result of	55
interaction between the	55
in the formation	55
binding of the	54
amino acid sequence	54
the golgi complex	54
the identification of	54
results suggest that	54
interactions between the	53
appears to be	53
insight into the	53
size of the	53
the amino acid	53
of the sars	53
structure and function	53
were able to	53
the existence of	53
the level of	52
and it is	52
known to be	52
proteins in the	52
nature of the	52
leads to the	52
a key role	52
which is a	52
the application of	52
found in the	52
depends on the	52
of a protein	51
at the plasma	51
than that of	51
there is no	51
change in the	51
the outer membrane	51
is due to	51
has been suggested	51
increase in the	50
in combination with	50
is associated with	50
viral rna synthesis	50
to be the	50
we present a	50
effect on the	49
members of the	49
mechanism of action	49
of a single	49
the active site	49
composition of the	49
between the two	49
is essential for	49
were used to	49
in the present	48
has been used	48
a role in	48
presence of a	48
the most common	48
information on the	48
is involved in	48
the nature of	48
human immunodeficiency virus	48
herpes simplex virus	48
a set of	47
because of the	47
was supported by	47
we have developed	47
mutations in the	47
the membrane and	47
the release of	47
are known to	47
dynamics of the	47
be involved in	47
the expression of	47
dependent on the	47
of the c	47
consistent with the	46
of dpap a	46
the aim of	46
has been proposed	46
the wild type	46
due to their	46
this work was	46
mechanism of the	46
stability of the	46
membrane of the	46
the fusion of	46
plasma membrane of	46
due to its	45
the membrane surface	45
key role in	45
extracorporeal life support	45
binding to the	45
of the interaction	45
the range of	45
class ii fusion	45
different types of	45
the influenza virus	45
in vitro and	45
the properties of	44
at acidic ph	44
to the vacuole	44
the target membrane	44
an increase in	44
presence of the	44
of the proteins	44
on the cell	44
here we present	44
results indicate that	44
insights into the	44
used for the	44
influenza virus hemagglutinin	44
the interaction with	43
seems to be	43
to elucidate the	43
the action of	43
and can be	43
addition to the	43
integral membrane proteins	43
isothermal titration calorimetry	43
of this study	43
the possibility of	43
supported by the	43
the basis of	43
structural and functional	43
studies of the	43
the fusion loop	42
of the binding	42
in the cytoplasm	42
we have used	42
have been shown	42
sequence of the	42
referred to as	42
for the first	42
is important to	42
state of the	42
side of the	42
structures of the	42
in the range	42
which can be	42
leads to a	42
with permission from	42
the context of	41
the crystal structure	41
have also been	41
as compared to	41
it was shown	41
indicate that the	41
the same time	41
of amino acids	41
cytoplasmic domain of	41
the transport of	41
in the fusion	41
in mammalian cells	41
to form a	41
of the influenza	41
is supported by	41
are associated with	41
the first time	41
and dynamics of	41
was shown to	41
of the enzyme	41
of action of	41
we showed that	40
at the cell	40
our understanding of	40
be used as	40
the viral envelope	40
residues in the	40
have been reported	40
based on a	40
suggests that the	40
the distribution of	40
similar to the	40
leading to the	40
were found to	40
attached to the	40
in recent years	40
the assembly of	40
of virus particles	39
of lipid rafts	39
it is a	39
will be discussed	39
of these proteins	39
the most important	39
close to the	39
fluorescence correlation spectroscopy	39
interact with the	39
respect to the	39
have been proposed	39
induced by the	39
is composed of	39
academy of sciences	39
on the membrane	38
been shown that	38
connected to the	38
in the context	38
organization of the	38
have been identified	38
each of the	38
bound to the	38
observed in the	38
caused by the	38
regions of the	38
fusion of the	38
it can be	38
thought to be	38
cells infected with	38
member of the	38
acts as a	38
is possible to	37
we investigated the	37
in the golgi	37
in the host	37
is known to	37
it is not	37
be used for	37
results in the	37
play an important	37
is the most	37
demonstrated that the	37
proteins involved in	37
as a model	37
it is important	37
mechanical properties of	37
structure of a	37
used in the	37
has not been	36
large number of	36
to the golgi	36
corresponding to the	36
work was supported	36
and in vivo	36
of dpap b	36
in the brain	36
effects of the	36
of antimicrobial peptides	36
suggested that the	36
in the plasma	36
the lack of	36
to the er	36
be due to	35
ii fusion proteins	35
end of the	35
of a membrane	35
was shown that	35
their ability to	35
shows that the	35
added to the	35
to characterize the	35
have to be	35
is consistent with	35
followed by a	35
we studied the	35
the mechanisms of	35
changes of the	35
bind to the	35
of enveloped viruses	35
model of the	35
of vesicular stomatitis	35
determined by the	35
the activation of	35
the morphology of	35
our results show	35
allowed us to	35
p r e	34
we have studied	34
in live cells	34
p r o	34
leaflet of the	34
o o f	34
o u r	34
dynamic light scattering	34
r o o	34
in agreement with	34
a l p	34
contribute to the	34
in the protein	34
at the membrane	34
we were able	34
also known as	34
membrane oxygenation for	34
depend on the	34
n a l	34
in the lipid	34
vitro and in	34
of the molecular	34
and that the	34
in case of	34
into the host	34
on the basis	34
r n a	34
l p r	34
are required for	34
play a role	34
is possible that	34
j o u	34
u r n	34
differences in the	34
in membrane fusion	34
out of the	33
the viral membrane	33
suggesting that the	33
dependence of the	33
in the viral	33
we have shown	33
to the cytoplasm	33
revealed that the	33
is responsible for	33
we have investigated	33
of the major	33
proteins of the	33
viral membrane fusion	33
data suggest that	33
have been developed	33
located at the	33
the degree of	33
in the cytoplasmic	33
indicated that the	33
to identify the	33
the form of	33
due to a	33
plays an important	33
is thought to	33
and the other	33
in the outer	33
supported lipid bilayers	33
assembly of the	33
at the interface	33
is a key	33
increase of the	32
studies have shown	32
is characterized by	32
membrane and the	32
the loss of	32
transport to the	32
the behavior of	32
the e protein	32
indicating that the	32
mouse hepatitis virus	32
the present work	32
by the presence	32
from the er	32
of the cytoplasmic	32
is an important	32
reprinted with permission	32
of the n	32
effects on the	32
step in the	32
determination of the	32
is used to	32
be associated with	32
is mediated by	32
is related to	32
shown in figure	32
of the s	32
located in the	32
host cell membrane	32
protein in the	32
on the structure	32
that it is	32
of the pore	31
in this context	31
of the e	31
in escherichia coli	31
and membrane fusion	31
crystal structures of	31
inserted into the	31
of the bilayer	31
core of the	31
for membrane fusion	31
the order of	31
the membrane is	31
length of the	31
of the structure	31
that have been	31
point of view	31
resonance energy transfer	31
similar to those	31
membrane proteins in	31
lead to the	31
has been reported	31
of the transmembrane	31
at room temperature	31
into the membrane	31
the severe acute	31
as a consequence	31
at the n	31
been found to	31
this work we	31
molecular mechanism of	31
in some cases	31
because of their	31
a family of	30
viral fusion proteins	30
of the complex	30
at low ph	30
in this case	30
information about the	30
needs to be	30
aim of this	30
can lead to	30
the present study	30
to each other	30
need to be	30
the transmembrane domain	30
wide variety of	30
is dependent on	30
is important for	30
the detection of	30
association of the	30
domain of dpap	30
mediated by the	30
of nfn membranes	30
structure and dynamics	30
the determination of	30
the organization of	30
the accumulation of	30
a role for	30
of the same	30
the molecular mechanisms	30
the outer leaflet	30
in the field	30
followed by the	30
the interior of	30
to measure the	30
department of chemistry	30
compared with the	30
the synthesis of	30
to improve the	30
the changes in	30
we propose that	30
components of the	30
this suggests that	30
to analyze the	29
conformational changes in	29
change of the	29
the actin cytoskeleton	29
will be presented	29
was carried out	29
face of the	29
proteins that are	29
the entry of	29
a wide variety	29
surface plasmon resonance	29
the first step	29
of viral rna	29
in the form	29
of the three	29
in the literature	29
of the fp	29
cleavage of the	29
into the cytoplasm	29
of the particles	29
is shown in	29
interactions with the	29
the molecular mechanism	29
the conformational change	29
is likely to	29
we have found	29
a large number	29
the interactions of	29
a model system	29
of amino acid	29
the length of	29
the protein is	29
the lumen of	29
of the molecule	29
proteins have been	29
reduction of the	29
to the apical	29
of the hydrophobic	29
to be involved	29
the possibility that	29
it was found	29
been proposed to	29
of this protein	29
the removal of	29
better understanding of	29
as in the	28
formed in the	28
of a novel	28
there is an	28
led to the	28
half of the	28
the endocytic pathway	28
interacts with the	28
has been observed	28
polarized epithelial cells	28
be important for	28
the conformation of	28
the generation of	28
these results suggest	28
is that the	28
localized to the	28
one or more	28
transported to the	28
the increase of	28
we developed a	28
at neutral ph	28
the secondary structure	28
the molecular level	28
for the design	28
contact with the	28
we find that	28
the affinity of	28
strand rna viruses	28
it should be	28
disruption of the	28
two types of	28
hydrophobic amino acids	28
contrast to the	28
the characterization of	28
have not been	28
has to be	28
from the cell	28
we present the	28
is caused by	28
been suggested that	28
has been demonstrated	28
inhibition of the	28
of these two	27
has been studied	27
attributed to the	27
conformation of the	27
used to study	27
from the membrane	27
and on the	27
considered to be	27
plasma membrane and	27
the relationship between	27
the membrane fusion	27
for the treatment	27
class i fusion	27
this is the	27
membrane proteins are	27
the orientation of	27
have been described	27
are present in	27
into the cell	27
observed for the	27
of host cell	27
the interactions between	27
the center of	27
or in the	27
important for the	27
affected by the	27
in the early	27
have been found	27
can be obtained	27
indicates that the	27
to the surface	27
the discovery of	27
in contact with	27
because of its	27
of the ha	27
of the er	27
resulted in the	27
be able to	27
have been studied	27
transport of the	27
of the peptides	27
features of the	27
is crucial for	27
of a new	27
of proteins in	26
of the dna	26
interactions of the	26
outer leaflet of	26
is similar to	26
parallel to the	26
of the main	26
a member of	26
the er and	26
of the native	26
with the host	26
the filter cake	26
the structural and	26
are thought to	26
component of the	26
of the target	26
the control of	26
a decrease in	26
of the cells	26
conformational changes of	26
investigation of the	26
of hepatitis c	26
in the regulation	26
department of physics	26
portion of the	26
the fusion process	26
which has been	26
in the er	26
in the development	26
the binding site	26
were shown to	26
an example of	26
the association of	26
in presence of	26
terminus of the	26
reproduced with permission	26
resulting in a	26
which is the	26
integral membrane protein	26
it is also	26
to the cytosol	26
along with the	26
orientation of the	26
with a high	26
is the main	26
was found that	26
infectious bronchitis virus	26
it is the	26
concentration of the	26
stages of the	26
of the particle	26
a lipid bilayer	26
identification of the	26
the purification of	26
of the lipids	26
of the receptor	25
the insertion of	25
this type of	25
to be associated	25
linked to the	25
the membrane of	25
in mdck cells	25
release of the	25
are responsible for	25
reactive oxygen species	25
nuclear magnetic resonance	25
plays a key	25
in infected cells	25
to examine the	25
activation of the	25
membrane fusion and	25
peptides derived from	25
the combination of	25
on the interaction	25
the er membrane	25
it is likely	25
cell membrane and	25
is likely that	25
form of the	25
agreement with the	25
its ability to	25
of the different	25
of the signal	25
the field of	25
with the lipid	25
of the total	25
essential for the	25
of the outer	25
we have also	25
a recent study	25
is believed to	25
of lipid bilayers	25
of the a	25
is regulated by	25
location of the	25
have been investigated	25
that has been	25
formed by the	25
in this way	25
is followed by	25
for the development	25
the location of	25
the potential to	25
to assess the	24
for the formation	24
the position of	24
differential scanning calorimetry	24
applied to the	24
evidence that the	24
to understand how	24
are found in	24
be responsible for	24
with the same	24
a model of	24
have found that	24
to provide a	24
and found that	24
conformational change in	24
dynamics simulations of	24
on the cytoplasmic	24
a total of	24
inner and outer	24
free energy of	24
the course of	24
in the first	24
resulted in a	24
majority of the	24
institute of biophysics	24
been suggested to	24
have investigated the	24
there are two	24
light on the	24
its interaction with	24
the ratio of	24
on the protein	24
likely to be	24
of the virion	24
to play a	24
characterization of a	24
to explain the	24
expression of the	24
this study we	24
at the molecular	24
at least one	24
biological effects of	24
of protein a	24
kinetics of the	24
to bind to	24
are important for	24
of the surface	24
at the c	24
can be applied	24
targeted to the	24
central nervous system	24
the origin of	24
quartz crystal microbalance	24
the growth of	24
to evaluate the	24
aspects of the	24
which have been	24
to the basolateral	24
in the following	24
by using a	24
of the system	24
the inner membrane	24
is capable of	24
in the solution	24
the inhibition of	24
the appearance of	24
lead to a	23
the permeate flux	23
the target cell	23
the understanding of	23
influence of the	23
the mechanical properties	23
in the past	23
to the protein	23
the viral genome	23
insertion of the	23
mechanism of membrane	23
has been described	23
belongs to the	23
proteins to the	23
to the presence	23
localization of the	23
immunodeficiency virus type	23
we investigate the	23
a crucial role	23
energy of the	23
of severe acute	23
protein of the	23
conformational change of	23
results in a	23
well as in	23
proteins such as	23
it is still	23
in the second	23
affinity of the	23
to describe the	23
fact that the	23
allows us to	23
at least in	23
the potential of	23
have developed a	23
to explore the	23
has been found	23
and has been	23
to form the	23
of living cells	23
we have been	23
the localization of	23
terminal domain of	23
that the protein	23
that in the	23
development of a	23
we demonstrate that	23
appeared to be	23
venovenous extracorporeal membrane	23
to be important	23
view of the	23
the result of	23
that there is	23
has shown that	23
used to determine	23
of this work	22
is essential to	22
mode of action	22
binds to the	22
ability of the	22
in the future	22
we used the	22
the apical membrane	22
the signal peptide	22
signal peptidase cleavage	22
cell plasma membrane	22
together with the	22
molecular basis of	22
the extent of	22
the lipid composition	22
green fluorescent protein	22
perpendicular to the	22
at the air	22
distribution of the	22
isolated from the	22
can be found	22
consists of a	22
is a major	22
this work is	22
was able to	22
characterized by a	22
orders of magnitude	22
the hepatitis c	22
the performance of	22
expression of nsp	22
regulation of the	22
knowledge of the	22
processes such as	22
transmembrane domain of	22
to have a	22
proteins can be	22
is present in	22
the composition of	22
and molecular dynamics	22
physical properties of	22
studies have been	22
are the most	22
host cell membranes	22
in this review	22
be related to	22
size exclusion chromatography	22
of the yeast	22
through the golgi	22
leading to a	22
is the first	22
we analyzed the	22
fraction of the	22
the introduction of	22
gene therapy vectors	22
in comparison with	22
of such a	22
could be used	22
of the channel	22
taking into account	22
diseases such as	22
the cells were	22
the increase in	22
crucial role in	22
we conclude that	22
shape of the	22
of the interface	22
the diameter of	21
the efficiency of	21
serve as a	21
more than one	21
mediated membrane fusion	21
but it is	21
a consequence of	21
this study was	21
data on the	21
to be used	21
difference between the	21
single virion tracking	21
be attributed to	21
was used as	21
to the development	21
membrane insertion of	21
institute of technology	21
the hydrophobic segment	21
the change in	21
that they are	21
the hydrophobic core	21
inside the cell	21
action of the	21
mechanism by which	21
in most cases	21
secondary structure of	21
bovine serum albumin	21
the biosynthesis of	21
for this purpose	21
was also observed	21
in relation to	21
the viral replication	21
have been observed	21
we propose a	21
to obtain a	21
mutation in the	21
is an integral	21
removal of the	21
is required to	21
segment of the	21
control of the	21
model for the	21
here we report	21
in a wide	21
of viral glycoproteins	21
of the fluorescence	21
the end of	21
we used a	21
of the wild	21
the glycoproteins of	21
of the cellular	21
the sequence of	21
data not shown	21
in polarized epithelial	21
surface area of	21
the protein and	21
the innate immune	21
is known about	21
lipid bilayer and	21
under physiological conditions	21
a model for	21
are shown in	21
some of these	21
only in the	21
membrane fusion is	21
the movement of	21
the side chain	21
which leads to	21
to the outer	21
case of the	21
of the membranes	21
the catalytic domain	21
in the c	21
in the human	21
only a few	21
composed of a	21
in complex with	21
fusion peptide of	21
the protein to	21
the incorporation of	21
have demonstrated that	21
description of the	20
on the lipid	20
interacting with the	20
the molecular basis	20
dimensional structure of	20
the fusion proteins	20
of the free	20
to reveal the	20
away from the	20
account for the	20
as shown by	20
of at least	20
in the process	20
order to obtain	20
been implicated in	20
to probe the	20
the induction of	20
the delivery of	20
to induce the	20
for the study	20
the basis for	20
the tip of	20
and of the	20
a change in	20
are used to	20
a part of	20
was observed for	20
the nervous system	20
be applied to	20
can be easily	20
deletion of the	20
is a protein	20
this indicates that	20
advantage of the	20
molecular mechanisms of	20
domains of the	20
of a few	20
are composed of	20
negatively charged lipids	20
within the cell	20
cells in the	20
is a powerful	20
rna replication complex	20
i fusion proteins	20
in a single	20
peptide derived from	20
the two membranes	20
be required for	20
in comparison to	20
over the last	20
intrinsically disordered proteins	20
lumen of the	20
to the lipid	20
of membrane protein	20
of the vesicles	20
simplex virus type	20
in both the	20
may be a	20
the semliki forest	20
it does not	20
reggiori et al	20
an integral membrane	20
is determined by	20
to better understand	20
be used in	20
this can be	20
at the single	20
the head group	20
of the coronavirus	20
site of the	20
they can be	20
into the lipid	20
protein structure and	20
are essential for	20
are characterized by	20
higher than that	20
belonging to the	20
of biological membranes	20
translocation across the	20
analysis of a	20
the isoelectric point	20
double membrane vesicles	20
is sufficient to	20
use of the	20
of the whole	20
the amino terminus	20
nm in diameter	20
is in the	20
murine leukemia virus	20
back to the	20
epidermal growth factor	20
virus membrane fusion	20
recent studies have	20
materials and methods	20
membrane fusion activity	20
the idea that	20
was applied to	19
c and c	19
we report the	19
of the first	19
may contribute to	19
in the study	19
important in the	19
and host cell	19
the results obtained	19
on the molecular	19
we demonstrated that	19
structural characterization of	19
of the catalytic	19
in a variety	19
it was observed	19
plasma membrane in	19
the response of	19
of proteins and	19
located on the	19
to the fusion	19
may lead to	19
demonstrate that the	19
to control the	19
data show that	19
of the other	19
the contact angle	19
characterized by the	19
been used in	19
of the envelope	19
of the entire	19
may not be	19
evidence for the	19
sars fp and	19
of a viral	19
in model membranes	19
incorporated into the	19
of the drug	19
borne encephalitis virus	19
the diffusion of	19
it will be	19
on the order	19
flock house virus	19
membrane fusion in	19
composite nfn membranes	19
it is now	19
observed that the	19
the type of	19
has led to	19
in the bilayer	19
in the virus	19
department of biophysics	19
by a single	19
the help of	19
the hypothesis that	19
values of the	19
of up to	19
of the amino	19
and for the	19
of the reaction	19
the modulation of	19
of negatively charged	19
the results are	19
confocal laser scanning	19
order to study	19
the aggregation of	19
our results suggest	19
apical and basolateral	19
the cell wall	19
to those of	19
the results show	19
transmission electron microscopy	19
by binding to	19
molecules in the	19
which may be	19
was studied by	19
of the inner	19
from the golgi	19
decrease in the	19
small angle x	19
of a cell	19
the concept of	19
in conjunction with	19
of these structures	19
is found in	19
the translocation of	19
of the antimicrobial	19
the establishment of	19
to the same	19
those of the	19
the impact of	19
have been successfully	19
allow us to	19
of the g	19
live cell imaging	19
the point of	19
lipid rafts in	19
plane of the	19
p x r	19
is not clear	19
are considered to	19
is achieved by	19
to be an	18
position of the	18
the conversion of	18
is also a	18
the intensity of	18
crucial for the	18
the investigation of	18
formation of an	18
in saccharomyces cerevisiae	18
existence of a	18
at the tip	18
it is unclear	18
the specificity of	18
red blood cells	18
details of the	18
influence on the	18
and stability of	18
in this process	18
little is known	18
of them are	18
of a large	18
structural basis for	18
all of the	18
relative to the	18
the evolution of	18
found to have	18
we focus on	18
be divided into	18
at the level	18
fused to the	18
high concentrations of	18
to create a	18
of dengue virus	18
but not in	18
protein and the	18
seem to be	18
the availability of	18
with the plasma	18
provided by the	18
of the endoplasmic	18
and sars ifp	18
act as a	18
be noted that	18
is critical for	18
amino acid sequences	18
function in the	18
of the actin	18
in figure a	18
these results indicate	18
we suggest that	18
around the isoelectric	18
a better understanding	18
the absence or	18
protein that is	18
morphology of the	18
the lipid membrane	18
the membrane to	18
development of the	18
early stages of	18
giant unilamellar vesicles	18
before and after	18
in this section	18
in vivo and	18
modulation of the	18
outer mitochondrial membrane	18
and in vitro	18
amino acids are	18
an increase of	18
the conformational changes	18
cells of the	18
membrane proteins and	18
may also be	18
the university of	18
roles in the	18
was observed that	18
is expected to	18
characteristics of the	18
known as the	18
basis for the	18
in the interaction	18
rational design of	18
specificity of the	18
in patients with	18
the cytoplasmic tail	18
is the only	18
university of california	18
be important in	18
from the endoplasmic	18
of the arterivirus	18
in the s	18
is an essential	18
were carried out	18
results of the	18
of viral membrane	18
are consistent with	18
at fluid interfaces	18
the experimental data	18
red blood cell	18
with the formation	18
the s domain	18
the host membrane	18
proportional to the	18
were transfected with	18
of the p	18
is controlled by	18
of the bacterial	18
the contribution of	18
lipid composition of	18
access to the	18
where they are	18
sides of the	18
in cells infected	18
antimicrobial activity of	18
of the transition	18
there are several	18
of cholesterol in	18
insertion into the	18
of the gm	18
the cytoplasmic membrane	18
amino acids of	18
a diameter of	18
the mode of	18
the in vitro	18
not required for	18
coronavirus spike protein	18
has been known	18
study was to	18
the need for	18
in eukaryotic cells	17
have the ability	17
for the interaction	17
to predict the	17
the construction of	17
in lipid rafts	17
membrane fusion by	17
properties of a	17
interest in the	17
taking advantage of	17
amino terminus of	17
not appear to	17
the search for	17
concentration in the	17
unfolding of the	17
an essential role	17
particles in the	17
terms of the	17
no effect on	17
by the formation	17
the native state	17
in more detail	17
our results indicate	17
are discussed in	17
and the formation	17
topology of the	17
with the help	17
of the cytoskeleton	17
contributes to the	17
to the target	17
and have been	17
basis of the	17
of the surrounding	17
released into the	17
the interface of	17
the cytoplasmic side	17
the separation of	17
the formation and	17
the strength of	17
at least two	17
necessary for the	17
the g protein	17
simulations of the	17
of a peptide	17
and the membrane	17
stomatitis virus glycoprotein	17
both in the	17
in a membrane	17
discussed in the	17
of the mechanism	17
good agreement with	17
the involvement of	17
can result in	17
used as an	17
in the central	17
been observed in	17
and they are	17
we study the	17
up to a	17
the replication of	17
and formation of	17
have studied the	17
which could be	17
it is known	17
identification of a	17
the membrane bilayer	17
should be noted	17
acid sequence of	17
different stages of	17
a class of	17
is known that	17
to increase the	17
associated with a	17
result in the	17
the advantage of	17
on the host	17
is derived from	17
the fusion loops	17
that may be	17
one of these	17
picture of the	17
have revealed that	17
new class of	17
have been characterized	17
there is evidence	17
rna replication complexes	17
s and s	17
the complexity of	17
center of the	17
supported lipid bilayer	17
the folding of	17
of the resulting	17
order to understand	17
area of the	17
of sindbis virus	17
results showed that	17
of protein structure	17
owing to the	17
influenza a virus	17
dissociation of the	17
role for the	17
the observation that	17
viruses such as	17
an in vitro	17
these data suggest	17
high degree of	17
intracellular transport of	17
is independent of	17
when compared to	17
in lipid bilayers	17
the risk of	17
density of the	17
amino acids in	17
we will present	17
of the env	17
membrane fusion of	17
in the peptide	17
of the four	17
fusion and fission	17
middle east respiratory	17
mechanisms by which	17
believed to be	17
molecular weight of	17
of protein folding	17
intensity of the	17
the virus particle	17
was determined by	17
proposed to be	17
van der waals	17
that are not	17
of the secretory	17
into the bilayer	17
the human genome	17
of both the	17
patients receiving venovenous	17
and the c	16
the outer mitochondrial	16
according to their	16
with and without	16
the fusion pore	16
the rsv env	16
which results in	16
of protein palmitoylation	16
results demonstrate that	16
m and m	16
can be explained	16
to monitor the	16
the influenza hemagglutinin	16
for the detection	16
to calculate the	16
the signal peptidase	16
protein is a	16
mutants of the	16
in the nucleus	16
to produce a	16
the cell is	16
to account for	16
the proteins were	16
in epithelial cells	16
are needed to	16
at the site	16
been identified in	16
interfere with the	16
and functional characterization	16
phase separation of	16
the recruitment of	16
regulated by the	16
been reported to	16
a review of	16
belong to the	16
cell surface and	16
is necessary for	16
focus on the	16
the lumenal domain	16
respiratory distress syndrome	16
not only the	16
shed light on	16
concentrations of the	16
by electron microscopy	16
lipid bilayers and	16
such that the	16
the most abundant	16
has recently been	16
of mouse hepatitis	16
a group of	16
parameters of the	16
in other words	16
here we show	16
of this enzyme	16
behavior of the	16
consists of two	16
and does not	16
obtained from the	16
the pathogenesis of	16
these proteins are	16
thickness of the	16
pass through the	16
shown in table	16
the process is	16
that the membrane	16
east respiratory syndrome	16
may be important	16
the spike protein	16
is given by	16
well as to	16
the inner leaflet	16
using a combination	16
by mass spectrometry	16
the goal of	16
for the membrane	16
in which a	16
play a key	16
of the hepatitis	16
the peptide and	16
this process is	16
to the host	16
american chemical society	16
in close proximity	16
in determining the	16
induce the formation	16
the viral glycoproteins	16
from the plasma	16
of the vesicle	16
as described above	16
known about the	16
the particle diameter	16
of the folding	16
is formed by	16
the behaviour of	16
and to the	16
at least three	16
in a cell	16
in the last	16
evidence for a	16
suggested to be	16
the cytoplasm to	16
can be observed	16
an overview of	16
formation of nano	16
fp and sars	16
the virus and	16
that the interaction	16
the plane of	16
temperature dependence of	16
viral rna replication	16
at the end	16
subunit of the	16
and inhibition of	16
the structures of	16
been used as	16
protein to the	16
into the cytosol	16
by measuring the	16
an alternative to	16
in the yeast	16
fusion peptides and	16
assumed to be	16
experiments showed that	16
we hypothesize that	16
on the contrary	16
it has also	16
of herpes simplex	16
the dengue virus	16
strength of the	16
with a diameter	16
of sendai virus	16
through the membrane	16
caused by a	16
particles at interfaces	16
the onset of	16
an understanding of	16
implicated in the	16
has been developed	16
with the cell	16
proteins from the	16
west nile virus	16
entry into the	16
sites of the	16
a signal sequence	16
level of the	16
be found in	16
is not yet	16
the viral rna	16
the immune system	16
of influenza hemagglutinin	16
the protein structure	16
serves as a	16
the last years	16
by increasing the	16
nsp and nsp	16
the fraction of	16
surface of a	16
in the vicinity	16
be considered as	16
laser scanning microscopy	16
to determine if	16
the membrane interface	16
env gene product	16
peptides in the	16
health and disease	16
the degradation of	16
the percentage of	16
presence of an	16
in real time	16
decrease of the	16
is driven by	16
as described in	16
analysis of protein	16
graduate school of	16
evolution of the	16
into the er	16
a powerful tool	16
of the initial	15
differences between the	15
in the target	15
binding site of	15
are derived from	15
this class of	15
modification of the	15
in the treatment	15
residues of the	15
been proposed that	15
to the other	15
of viral proteins	15
structural changes in	15
broad range of	15
to be more	15
of the chromophore	15
from the host	15
of viral entry	15
from to nm	15
have been suggested	15
to the c	15
a matter of	15
the internalization of	15
lipid rafts and	15
to be considered	15
membrane oxygenation in	15
the difference in	15
able to bind	15
to reduce the	15
a conformational change	15
activity in the	15
the central nervous	15
could not be	15
carried out in	15
efficiency of the	15
outer membrane vesicles	15
we have previously	15
a mixture of	15
were analyzed by	15
to generate a	15
been described in	15
development of new	15
the ph dependence	15
to changes in	15
rate of the	15
the attachment of	15
resulting in the	15
may be the	15
of proteins that	15
been widely used	15
more likely to	15
we observed that	15
of extracorporeal membrane	15
which are known	15
has been widely	15
properties of these	15
modulated by the	15
rest of the	15
we report a	15
is a well	15
of the hiv	15
key step in	15
present on the	15
process of the	15
motion of the	15
with the target	15
particles at fluid	15
different cell types	15
of nanoparticles on	15
the membrane by	15
recent advances in	15
and release of	15
fourier transform infrared	15
for the production	15
was used for	15
in a large	15
so that the	15
supported by a	15
can be divided	15
the sensitivity of	15
well as their	15
molecular dynamics simulation	15
based on these	15
the most promising	15
also in the	15
endosomes and lysosomes	15
for the purification	15
peptide and the	15
in the two	15
of the semliki	15
a major role	15
widely used in	15
the crystal structures	15
subunits of the	15
a highly conserved	15
covalently linked to	15
been used for	15
the topology of	15
due to an	15
quantitative analysis of	15
integrity of the	15
each of these	15
in many cases	15
single molecule fluorescence	15
the protein in	15
of the second	15
the vicinity of	15
also found that	15
residues at the	15
membrane association of	15
expressed in the	15
the particles are	15
to be required	15
in the inner	15
the shape of	15
the tm domain	15
of amyloid fibrils	15
of the replication	15
the negatively charged	15
of the severe	15
been known to	15
of plasma membrane	15
in view of	15
ratio of the	15
early and late	15
the reduction of	15
growth factor receptor	15
much of the	15
we believe that	15
internalization of the	15
we aim to	15
is governed by	15
proteins and lipids	15
it is worth	15
considered as a	15
their interactions with	15
from that of	15
order to investigate	15
be explained by	15
at the surface	15
rna virus replication	15
of viral fusion	15
it may be	15
the preparation of	15
with that of	15
delivery to the	15
with the increase	15
structural properties of	15
is induced by	15
were found in	15
in the transport	15
on the mechanism	15
a way that	15
it is shown	15
in biological systems	15
approach based on	15
the core of	15
the class i	15
was added to	15
is necessary to	15
destabilization of the	15
fusion activity of	15
membrane fusion process	15
is accompanied by	15
the cytoplasm and	15
of the spike	15
membrane rearrangements induced	15
the vesicular stomatitis	15
giving rise to	15
this is a	15
the rest of	15
a component of	15
can be monitored	14
proved to be	14
correspond to the	14
for membrane proteins	14
vivo and in	14
investigate the effect	14
the most widely	14
cov e protein	14
and regulation of	14
calculated from the	14
on the same	14
in spite of	14
cells and tissues	14
is a crucial	14
in the latter	14
that lead to	14
it was suggested	14
most of these	14
even though the	14
rearrangements induced by	14
of which are	14
to obtain the	14
is still a	14
the transmembrane and	14
reported in the	14
on the structural	14
antimicrobial peptides and	14
correlated with the	14
a broad range	14
ranging from to	14
response to the	14
and structure of	14
was confirmed by	14
catalytic domain of	14
is the case	14
a platform for	14
c virus replication	14
of the d	14
can be modulated	14
golgi apparatus and	14
adjacent to the	14
the biological effects	14
acute respiratory distress	14
a high degree	14
a central role	14
roberts et al	14
of a number	14
syndrome coronavirus spike	14
in the liver	14
of the high	14
the cleavage site	14
there was a	14
this study is	14
membrane can be	14
between these two	14
were observed in	14
membrane proteins of	14
parts of the	14
in the liquid	14
the content of	14
active site of	14
hydrophobic core of	14
result of the	14
layer of the	14
gives rise to	14
as determined by	14
is inhibited by	14
that leads to	14
expansion of the	14
with lipid membranes	14
and membrane proteins	14
can then be	14
detected in the	14
of human immunodeficiency	14
er and golgi	14
using this approach	14
we have recently	14
work is to	14
of a small	14
the virus to	14
a new class	14
total internal reflection	14
assembly and budding	14
during extracorporeal membrane	14
we will show	14
the density of	14
prior to the	14
of this process	14
of the polymer	14
many of the	14
average diameter of	14
method for the	14
focused on the	14
role of this	14
of the modified	14
leu leu leu	14
within the er	14
with the hydrophobic	14
terminal region of	14
the antimicrobial peptide	14
in the sequence	14
for the viral	14
an inhibitor of	14
on the environment	14
of the glycoproteins	14
of proteins with	14
is still unknown	14
interior of the	14
such as those	14
have been applied	14
for drug delivery	14
remains to be	14
the extracellular matrix	14
italian institute of	14
the way for	14
in the endoplasmic	14
be mediated by	14
described in the	14
not fully understood	14
of the mutant	14
protein interactions and	14
with the aim	14
fusion proteins are	14
even in the	14
treatment of the	14
correlation between the	14
evidence suggests that	14
activity of a	14
to generate the	14
proteins and the	14
in the secretory	14
kim et al	14
and amino acids	14
at the amino	14
protein interactions in	14
is a member	14
is modulated by	14
cells such as	14
the cytoplasmic face	14
removed from the	14
the viral fusion	14
there have been	14
to the inner	14
the viral and	14
and assembly of	14
the latter is	14
studies showed that	14
the creation of	14
the reaction of	14
we present an	14
sensitive to the	14
of science and	14
a direct role	14
amino acid composition	14
of the t	14
the human body	14
on the viral	14
the cytoplasm of	14
of the sample	14
do not have	14
difference in the	14
a subset of	14
the mechanism by	14
of the formation	14
strand rna virus	14
there are three	14
the differences in	14
upon binding to	14
of fusion peptides	14
to act as	14
and the lipid	14
world health organization	14
insertion of a	14
first step of	14
divided into two	14
in the extracellular	14
are crucial for	14
or presence of	14
amino acids and	14
can be achieved	14
the hydrolysis of	14
aim is to	14
with regard to	14
this protein is	14
a transmembrane protein	14
domains in the	14
the contact line	14
df cells were	14
the kda antigen	14
proven to be	14
for purification of	14
protein palmitoylation in	14
cell membranes and	13
maturation of the	13
for min at	13
could lead to	13
and form ii	13
class of proteins	13
are in the	13
rous sarcoma virus	13
able to interact	13
the virus is	13
to follow the	13
interactions in the	13
single molecule level	13
of the b	13
the case for	13
of arb on	13
as they are	13
diameter of nm	13
to reach the	13
membranes of the	13
into account the	13
as a novel	13
is not a	13
of the ligand	13
loss of the	13
the s protein	13
can be determined	13
for ellipsoidal particles	13
driving force for	13
generated by the	13
is limited by	13
for use in	13
is used for	13
large unilamellar vesicles	13
circular dichroism and	13
as an example	13
site in the	13
resistance of the	13
with each other	13
translocation of the	13
gated ion channels	13
the c terminus	13
by molecular dynamics	13
experiments show that	13
type and mutant	13
and mechanisms of	13
in aqueous solution	13
the occurrence of	13
based on their	13
of infected cells	13
cd and cd	13
rsv env gene	13
to note that	13
driven by the	13
virus particles are	13
has been extensively	13
a key step	13
not well understood	13
are known as	13
has been identified	13
of the conformational	13
the fluid phase	13
higher than the	13
gp and gp	13
domain in the	13
step of the	13
the particle size	13
peptide from the	13
stabilization of the	13
structural features of	13
proteins and their	13
it was also	13
of the process	13
forms of the	13
and in particular	13
membrane curvature and	13
as described previously	13
for a long	13
the click chemistry	13
it is necessary	13
science and technology	13
from the tgn	13
k t b	13
have been made	13
from the c	13
at a time	13
the dependence of	13
architecture of the	13
the transfer of	13
one or two	13
evaluation of the	13
biochemical characterization of	13
life support organization	13
we determined the	13
new insights into	13
respiratory syncytial virus	13
the ionic strength	13
of the molecules	13
is located in	13
use of ecls	13
in the light	13
of the energy	13
of proteins to	13
of the rsv	13
and it has	13
was expressed in	13
to detect the	13
better understand the	13
and atomic force	13
class i and	13
the toxicity of	13
for virus replication	13
the source of	13
as previously described	13
molecular details of	13
is linked to	13
by using the	13
of intracellular membranes	13
is expressed in	13
reported that the	13
see materials and	13
expression of a	13
peptides can be	13
ordering of the	13
released from the	13
formation of these	13
the inner and	13
early stage of	13
are formed by	13
to the high	13
at this stage	13
order to find	13
are based on	13
states of the	13
has been the	13
electrostatic interactions between	13
the details of	13
on the formation	13
find that the	13
to test the	13
also been shown	13
fragment of the	13
for studying the	13
taken into account	13
the early stages	13
family of proteins	13
physicochemical properties of	13
widely used for	13
of the interactions	13
to form an	13
absence or presence	13
in cancer cells	13
it is of	13
such as in	13
structure in the	13
the basolateral surface	13
commonly used in	13
the de novo	13
cytoplasmic face of	13
to stabilize the	13
these structures are	13
membrane oxygenation support	13
of these peptides	13
reggiori and klionsky	13
play a crucial	13
virus e protein	13
and so on	13
could also be	13
report on the	13
some of them	13
of the hemagglutinin	13
and most of	13
of the extracellular	13
the radius of	13
with lipid rafts	13
function of temperature	13
were obtained by	13
the membranes of	13
made up of	13
a long time	13
the aggregation process	13
diameter of the	13
we are able	13
membranes has been	13
is the major	13
we do not	13
responsible for this	13
electron paramagnetic resonance	13
acting on the	13
is triggered by	13
to a more	13
high levels of	13
enabled us to	13
by the fact	13
on the right	13
dynamics of a	13
to develop a	13
light scattering and	13
included in the	13
the class ii	13
to the cytoplasmic	13
electron spin resonance	13
electron microscopy and	13
the protein was	13
in health and	13
of the family	13
than in the	13
of more than	13
been demonstrated that	13
role played by	13
is found to	13
cytoplasmic domains of	13
directly to the	13
results have been	13
and identification of	13
conclude that the	13
our data suggest	13
the lipid head	13
scanning electron microscopy	13
of conformational changes	13
drug delivery systems	13
genome into the	13
in both cases	13
by fluorescence spectroscopy	13
in formation of	13
or absence of	13
been associated with	13
of the putative	13
the gm activator	13
study on the	13
a and a	13
was suggested that	13
the folding and	13
complex in the	13
functional properties of	13
was observed in	13
localized in the	13
fluorescence resonance energy	13
tip of the	13
i will present	13
remain to be	13
formation of amyloid	13
of a specific	13
cells were transfected	13
separation of the	13
transmembrane and cytoplasmic	13
of cellular membranes	13
regard to the	13
to the n	13
of the assembly	13
for more than	13
by the interaction	13
lower than that	13
the env gene	13
of the flavivirus	13
atom molecular dynamics	13
be achieved by	13
a critical role	13
essential role in	13
showed that a	13
in the lung	13
of the full	13
means that the	13
in the n	13
estimated to be	13
also be used	13
have the potential	12
peptidase cleavage site	12
in our study	12
cells with a	12
modified endoplasmic reticulum	12
the measurement of	12
estimation of the	12
interaction of a	12
of virus entry	12
of photosystem ii	12
of class i	12
the membrane in	12
with a single	12
structural analysis of	12
it is believed	12
and kinetics of	12
the energy of	12
it is well	12
performance of the	12
the uptake of	12
in the structure	12
most commonly used	12
introduced into the	12
coronavirus envelope protein	12
to regulate the	12
structural studies of	12
endoplasmic reticulum to	12
and cell biology	12
of the membranous	12
using nmr spectroscopy	12
are related to	12
the purpose of	12
molecular biology and	12
proteolytic cleavage of	12
pore formation and	12
of integral membrane	12
by a combination	12
the in vivo	12
free energy landscape	12
we report on	12
of the genome	12
of the double	12
critical role in	12
which has a	12
protein can be	12
the membrane proteins	12
the signal sequence	12
requires the presence	12
membrane proteins into	12
to inhibit the	12
within the membrane	12
the intrinsically disordered	12
as it is	12
exposed to the	12
of the contact	12
membrane topology of	12
the peptide to	12
absorption and fluorescence	12
a is the	12
steps of the	12
an amino acid	12
membrane lipid composition	12
can be seen	12
relies on the	12
be carried out	12
profile of the	12
comparison of the	12
the presence and	12
of this pathway	12
using circular dichroism	12
in the polymer	12
of in vitro	12
endocytosis of the	12
the low ph	12
network of modified	12
is highly conserved	12
directly involved in	12
the ph of	12
for in vivo	12
lumenal domain of	12
presence of both	12
were studied by	12
the prediction of	12
of membrane lipids	12
a novel approach	12
negatively charged phospholipids	12
there are many	12
of the presence	12
we have demonstrated	12
formation of dmvs	12