journal-jVirolMethods-cord


Introduction

This is a Distant Reader "study carrel", a set of structured data intended to help the student, researcher, or scholar use & understand a corpus.

This study carrel was created on 2021-05-30 by Eric Morgan <emorgan@nd.edu>. The carrel was created using the Distant Reader cord process, and the input was the result of a query applied to a local mirror of CORD, a data set of scholarly articles on the topic of COVID-19. The actual query was: facet_journal:"J Virol Methods". The results of this query were saved in a cache and transformed into a set of plain text files. All of the analysis -- "reading" -- has been done against these plain text files. For example, a short narrative report has been created. This Web page is a more verbose version of that report.

All study carrels are self-contained -- no Internet connection is necessary to use them. Download this carrel for offline reading. The carrel is made up of many subdirectories and data files. The manifest describes each one in greater detail.

Size

There are 115 item(s) in this carrel, and this carrel is 339,301 words long. Each item in your study carrel is, on average, 3,945 words long. If you dig deeper, then you might want to save yourself some time by reading a shorter item. On the other hand, if your desire is for more detail, then you might consider reading a longer item. The following charts illustrate the overall size of the carrel.

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histogram of sizes
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box plot of sizes

Readability

On a scale from 0 to 100, where 0 is very difficult and 100 is very easy, the documents have an average readability score of 53. Consequently, if you want to read something more simplistic, then consider a document with a higher score. If you want something more specialized, then consider something with a lower score. The following charts illustrate the overall readability of the carrel.

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histogram of readability
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box plot of readability

Word Frequencies

By merely counting & tabulating the frequency of individual words or phrases, you can begin to get an understanding of the carrel's "aboutness". Excluding "stop words", some of the more frequent words include:

pcr, virus, rt, assay, detection, samples, using, rna, viral, time, cells, used, viruses, positive, real, sars, respiratory, protein, influenza, gene, infection, specific, cell, study, reaction, coronavirus, primers, dna, min, method, results, two, assays, amplification, human, sensitivity, cov, detected, sequence, clinical, infected, strains, based, negative, also, one, methods, primer, table, analysis

Using the three most frequent words, the three files containing all of those words the most are Multiplex real-time RT-PCR assay for bovine viral diarrhea virus type 1, type 2 and HoBi-like pestivirus, Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses, and Detection of subgenomic mRNA of feline coronavirus by real-time polymerase chain reaction based on primer-probe energy transfer (P-sg-QPCR).

The most frequent two-word phrases (bigrams) include:

time rt, pcr assay, time pcr, reverse transcription, viral rna, acute respiratory, polymerase chain, chain reaction, respiratory syndrome, clinical samples, sybr green, nested pcr, influenza virus, infectious bronchitis, respiratory syncytial, pcr assays, real time, syncytial virus, severe acute, porcine epidemic, cell culture, isothermal amplification, conventional rt, respiratory viruses, nucleic acid, bronchitis virus, mediated isothermal, diarrhea virus, methods doi, doc id, virol methods, cord uid, epidemic diarrhea, infectious peritonitis, feline infectious, detection limit, positive samples, respiratory tract, influenza viruses, reverse transcriptase, rapid detection, lamp assay, agarose gel, serum samples, applied biosystems, transmissible gastroenteritis, cell lines, viral load, pcr products, infected cells

And the three file that use all of the three most frequent phrases are Development of universal SYBR Green real-time RT-PCR for the rapid detection and quantitation of bovine and porcine toroviruses Development of SYBR Green real-time RT-PCR for rapid detection, quantitation and diagnosis of unclassified bovine enteric calicivirus, and Multiplex real-time RT-PCR assay for bovine viral diarrhea virus type 1, type 2 and HoBi-like pestivirus.

While often deemed superficial or sophomoric, rudimentary frequencies and their associated "word clouds" can be quite insightful:

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unigrams
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bigrams

Keywords

Sets of keywords -- statistically significant words -- can be enumerated by comparing the relative frequency of words with the number of times the words appear in an entire corpus. Some of the most statistically significant keywords in the carrel include:

pcr, rna, sars, lamp, ibv, elisa, pedv, rsv, dna, cell, virus, protein, usa, h1n1, tgev, sequence, phev, h275y, green, fipv, fip, feline, cdv, yhv, western, vp7, vero, ube2d2, tsv, tof, tmev, test, technique, tcid, swab, surface, spike, spf, soiv, silico, siga, shrt, sephadex, rva, rtv, rpa, qpcr, qcm, prv, prrsv

And now word clouds really begin to shine:

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keywords

Topic Modeling

Topic modeling is another popular approach to connoting the aboutness of a corpus. If the study carrel could be summed up in a single word, then that word might be pcr, and Silencing of HTLV-1 gag and env genes by small interfering RNAs in HEK 293 cells is most about that word.

If the study carrel could be summed up in three words ("topics") then those words and their significantly associated titles include:

  1. pcr - Sampling methods for recovery of human enteric viruses from environmental surfaces
  2. virus - A new Sephadex™-based method for removing microbicidal and cytotoxic residues when testing antiseptics against viruses: Experiments with a human coronavirus as a model
  3. sars - Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus

If the study carrel could be summed up in five topics, and each topic were each denoted with three words, then those topics and their most significantly associated files would be:

  1. sars, virus, protein - Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus
  2. pcr, rt, virus - Rapid detection and differentiation of dengue virus serotypes by NS1 specific reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay in patients presenting to a tertiary care hospital in Hyderabad, India
  3. pcr, 10, rt - Sampling methods for recovery of human enteric viruses from environmental surfaces
  4. virus, pcr, rna - Detection of subgenomic mRNA of feline coronavirus by real-time polymerase chain reaction based on primer-probe energy transfer (P-sg-QPCR)
  5. cells, 10, virus - A new Sephadex™-based method for removing microbicidal and cytotoxic residues when testing antiseptics against viruses: Experiments with a human coronavirus as a model

Moreover, the totality of the study carrel's aboutness, can be visualized with the following pie chart:

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topic model

Noun & Verbs

Through an analysis of your study carrel's parts-of-speech, you are able to answer question beyonds aboutness. For example, a list of the most frequent nouns helps you answer what questions; "What is discussed in this collection?":

virus, assay, detection, samples, time, cells, viruses, protein, infection, gene, influenza, cell, reaction, study, primers, method, results, min, assays, amplification, coronavirus, sensitivity, sequence, strains, •, sample, sequences, analysis, primer, type, dna, antibodies, methods, test, disease, ×, control, antibody, specificity, strain, ml, copies, patients, infections, data, kit, probe, pcr, expression, serum

An enumeration of the verbs helps you learn what actions take place in a text or what the things in the text do. Very frequently, the most common lemmatized verbs are "be", "have", and "do"; the more interesting verbs usually occur further down the list of frequencies:

using, detect, show, tested, based, contains, including, determined, infect, followed, developed, described, performed, compare, obtained, found, identify, provided, collected, according, indicated, confirmed, observed, evaluated, causes, associated, purified, reported, demonstrating, carried, amplify, isolated, added, expressed, designed, extracted, produce, targeting, generate, incubated, nested, required, mediate, increase, allows, assess, resulting, gives, diluted, calculated

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nouns
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verbs

Proper Nouns

An extraction of proper nouns helps you determine the names of people and places in your study carrel.

PCR, RT, RNA, SARS, C, Fig, M, CoV, LAMP, PEDV, ELISA, RSV, •, IBV, USA, S, H1N1, Table, A, DNA, sera, N, SYBR, PBS, Green, −1, TM, TaqMan, FCoV, Vero, TGEV, J, T, MS, CoV-2, China, L, CDV, B, pH, PRV, HCoV, bp, C., Germany, CSFV, Virol, Methods, CA, mRNA

An analysis of personal pronouns enables you to answer at least two questions: 1) "What, if any, is the overall gender of my study carrel?", and 2) "To what degree are the texts in my study carrel self-centered versus inclusive?"

it, we, its, their, our, they, i, his, them, he, us, itself, her, hnov, wb103, she, one, hnovs, evlps, clustalx, bl21-codonplus(de3)-ripl, pcv2, themselves, serotype-, rv174-rv177, ribvs, my

Below are words cloud of your study carrel's proper & personal pronouns.

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proper nouns
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pronouns

Adjectives & Verbs

Learning about a corpus's adjectives and adverbs helps you answer how questions: "How are things described and how are things done?" An analysis of adjectives and adverbs also points to a corpus's overall sentiment. "In general, is my study carrel positive or negative?"

viral, positive, real, respiratory, specific, clinical, human, negative, different, porcine, high, infectious, rapid, molecular, diagnostic, sensitive, conventional, standard, acute, anti, non, new, bovine, canine, low, severe, feline, reverse, single, recombinant, quantitative, higher, available, novel, several, present, like, first, avian, nucleic, similar, lower, infected, important, total, large, wild, syncytial, isothermal, significant

also, respectively, however, well, previously, highly, therefore, significantly, approximately, recently, first, furthermore, subsequently, currently, even, still, prior, serially, directly, closely, specifically, naturally, less, additionally, simultaneously, newly, especially, briefly, relatively, often, usually, moreover, successfully, least, commercially, worldwide, experimentally, easily, rapidly, particularly, widely, slightly, finally, frequently, commonly, twice, generally, overnight, single, together

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adjectives
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adverbs

Next steps

There is much more to a study carrel than the things outlined above. Use this page's menubar to navigate and explore in more detail. There you will find additional features & functions including: ngrams, parts-of-speech, grammars, named entities, topic modeling, a simple search interface, etc.

Again, study carrels are self-contained. Download this carrel for offline viewing and use.

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