trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
in patients with	987
critically ill patients	750
intensive care unit	568
in critically ill	471
respiratory distress syndrome	423
acute respiratory distress	413
the use of	411
of patients with	351
in the icu	344
length of stay	300
is associated with	269
of this study	265
a total of	262
as well as	252
the aim of	248
study was to	243
patients with severe	240
the intensive care	239
was associated with	232
to the icu	226
this study was	220
admitted to the	220
patients admitted to	206
according to the	202
there was no	196
the risk of	196
of the patients	185
the number of	184
the presence of	181
the incidence of	179
crit care doi	177
patients with covid	175
associated with a	172
in this study	170
severe acute respiratory	167
ill patients with	166
aim of this	165
to evaluate the	164
patients with sepsis	161
acute lung injury	160
the effect of	159
patients in the	155
one of the	152
extracorporeal membrane oxygenation	149
of the study	147
with regard to	146
in order to	145
to assess the	143
in intensive care	143
acute kidney injury	142
based on the	142
in the study	141
patients with a	139
of critically ill	139
due to the	138
risk factors for	137
the development of	137
a systematic review	130
in the intensive	129
was defined as	129
between the two	127
acute respiratory failure	126
to jurisdictional claims	125
in published maps	125
maps and institutional	125
remains neutral with	125
neutral with regard	125
jurisdictional claims in	125
published maps and	125
springer nature remains	125
claims in published	125
nature remains neutral	125
regard to jurisdictional	125
and institutional affiliations	125
was used to	124
the need for	124
included in the	124
the two groups	123
and septic shock	123
the impact of	122
patients with acute	122
the role of	120
acute respiratory syndrome	120
the management of	119
of intensive care	118
renal replacement therapy	118
intensive care units	117
of mechanical ventilation	113
the most common	113
patients were included	113
the treatment of	113
in our study	109
the study was	108
were included in	108
with acute respiratory	108
note springer nature	107
mechanically ventilated patients	107
associated with increased	105
the effects of	103
there was a	103
the time of	102
and approved the	101
systematic review and	101
risk factor for	101
associated with the	100
the present study	100
total of patients	100
the critically ill	99
in icu patients	99
study is to	98
the severity of	98
the fi rst	96
sepsis and septic	96
this study is	96
number of patients	95
for patients with	95
the end of	94
approved the final	94
to determine the	94
are associated with	94
no competing interests	93
in terms of	93
in mechanically ventilated	92
morbidity and mortality	92
review and meta	91
that they have	91
an increase in	91
the duration of	90
there were no	90
they have no	90
have no competing	89
in septic shock	89
read and approved	88
before and after	88
there is a	88
invasive mechanical ventilation	88
the association between	87
at least one	87
the final manuscript	87
of patients were	87
organ failure assessment	87
the results of	86
declare that they	86
the emergency department	86
the rate of	85
factors associated with	85
in addition to	85
the control group	85
of the manuscript	84
and outcomes of	84
with septic shock	83
patients with ards	83
the authors declare	83
in the lung	82
admission to the	82
icu and hospital	82
authors declare that	81
mortality in patients	81
the study period	81
we aimed to	80
were admitted to	80
in patients who	80
and in the	80
compared with the	80
hospitalized patients with	79
of patients who	79
lower respiratory tract	78
of our study	78
in critical care	77
the diagnosis of	77
respiratory syndrome coronavirus	76
the level of	76
significantly higher in	75
been shown to	75
at the end	75
the purpose of	75
approved by the	74
in the first	74
at the time	74
h n influenza	73
of critical care	73
in both groups	73
the majority of	73
cuff leak test	72
to investigate the	72
with severe sepsis	72
related to the	72
patients who were	72
cause of death	71
sequential organ failure	71
hospital cardiac arrest	71
traumatic brain injury	71
among patients with	71
prospective observational study	71
not associated with	71
the primary outcome	71
are shown in	70
the absence of	70
of critical illness	69
patients treated with	69
has not been	69
risk of death	69
authors read and	69
in these patients	69
patients who had	69
a number of	68
during the first	68
has been shown	68
ethics approval and	68
high risk of	67
analysis was performed	67
consent to participate	67
severe sepsis and	66
critical care medicine	66
approval and consent	66
and consent to	66
apache ii score	66
with and without	65
the importance of	65
was observed in	65
analysis of the	65
icu length of	65
in the treatment	65
independently associated with	65
contributed to the	64
can be used	64
septic shock patients	64
area under the	64
were associated with	64
in the critically	64
higher in the	64
more likely to	63
patients with septic	63
than in the	63
randomized controlled trial	63
retrospective cohort study	63
flow nasal cannula	63
in case of	62
the relationship between	62
severity of illness	62
of icu admission	62
we performed a	62
was significantly higher	62
was approved by	62
in the emergency	61
no significant difference	61
mortality rate was	61
of septic shock	61
because of the	61
pandemic influenza a	61
patients who received	61
the patients with	60
to reduce the	60
be associated with	60
chronic obstructive pulmonary	60
the proportion of	60
be used to	60
mean arterial pressure	60
clinical characteristics of	60
primary outcome was	59
we did not	59
no difference in	59
after cardiac arrest	59
adult patients with	59
compared to the	59
there is no	59
the icu and	59
and hospital mortality	59
is one of	58
in the present	58
the acute respiratory	58
obstructive pulmonary disease	58
of these patients	58
middle east respiratory	58
east respiratory syndrome	58
the quality of	57
part of the	57
who did not	57
and safety of	57
in all patients	57
aim of the	57
the pathogenesis of	57
as a result	57
the prevalence of	56
are needed to	56
in response to	56
the length of	56
aim was to	56
well as the	56
during the study	55
was higher in	55
significant difference in	55
hospital length of	55
it has been	55
purpose of this	55
role in the	54
we conducted a	54
of icu stay	54
study was conducted	54
in the united	53
was performed using	53
the course of	53
in septic patients	53
of stay in	53
we found that	53
was no difference	53
to be a	53
this is a	52
respiratory syncytial virus	52
quality of life	52
the first hours	52
of severe sepsis	51
of data and	51
were used to	51
the patients were	51
the current study	51
as compared with	51
a decrease in	51
in hospitalized patients	51
should not be	51
should be considered	51
were divided into	51
was to evaluate	50
in the control	50
associated with mortality	50
in the non	50
for critically ill	50
to the intensive	50
influenza a virus	50
end of the	50
found to be	50
increased risk of	50
shown in table	49
mechanical ventilation and	49
admitted to icu	49
induced lung injury	49
pneumonia in wuhan	49
the berlin definition	49
the united states	49
the onset of	49
of the disease	49
a prospective observational	49
within hours of	48
patients who underwent	48
and length of	48
in acute respiratory	48
the objective of	48
of the most	48
sensitivity and specificity	48
and mortality in	48
the occurrence of	48
the first h	48
of patients admitted	48
in the management	48
participated in the	47
been associated with	47
study was approved	47
efficacy and safety	47
we hypothesized that	47
analyses were performed	47
the mortality rate	47
was performed in	47
for more than	46
at high risk	46
icu patients with	46
this was a	46
have shown that	46
of severe acute	46
patients infected with	46
our study was	46
involved in the	46
patients with and	46
data were collected	46
was to assess	46
a risk factor	46
were treated with	46
patients with suspected	46
is a common	45
was to determine	45
all authors read	45
of the patient	45
to describe the	45
the lack of	45
open lung biopsy	45
most of the	45
the context of	45
was not associated	45
the degree of	45
group of patients	45
all patients were	45
to compare the	45
the levels of	44
did not differ	44
of hospital stay	44
availability of data	44
patients were admitted	44
the expression of	44
in adult patients	44
informed consent was	44
duration of mechanical	44
may be a	44
associated with an	43
with respect to	43
has been reported	43
can lead to	43
and chronic health	43
tumor necrosis factor	43
mortality in the	43
data and materials	43
of death in	43
associated with higher	43
a reduction in	43
hypoxemic respiratory failure	43
of the data	43
intensive care medicine	42
during mechanical ventilation	42
after cardiac surgery	42
the efficacy of	42
patients had a	42
as part of	42
patients who are	42
were enrolled in	42
electrical impedance tomography	42
for the treatment	42
need to be	42
patients were enrolled	42
review of the	42
the first days	42
may lead to	41
within the first	41
randomized controlled trials	41
of the lung	41
patients who died	41
systemic inflammatory response	41
as compared to	41
signifi cant diff	41
used in the	41
proportion of patients	41
in patients undergoing	41
in the context	41
of all patients	41
available from the	41
in the ed	41
to participate not	41
was conducted in	41
participate not applicable	41
multiple organ failure	40
was found in	40
or septic shock	40
objective of this	40
a retrospective cohort	40
in the early	40
with increased mortality	40
of acute respiratory	40
between the groups	40
prospective cohort study	40
and patients with	40
length of hospital	40
in accordance with	40
the same time	40
partial pressure of	40
was to investigate	40
randomized clinical trial	40
higher in patients	40
from january to	40
is important to	39
results of the	39
may not be	39
to have a	39
in combination with	39
in the absence	39
associated with poor	39
in critical illness	39
acute renal failure	39
a prospective study	39
avian influenza a	39
was no significant	39
mean age was	39
a h n	39
it is important	39
the administration of	39
was obtained from	39
at the same	39
outcomes of patients	39
septic shock and	39
o r ratio	39
patients with pneumonia	39
for acute respiratory	39
no signifi cant	38
for the management	38
study of patients	38
acute physiology and	38
on the other	38
a retrospective study	38
at icu admission	38
the most frequent	38
lung injury and	38
admitted to our	38
a variety of	38
would like to	38
with novel coronavirus	38
length of icu	38
patients with sars	38
th and th	38
patients were divided	38
physiology and chronic	38
and acute respiratory	38
difference between the	38
showed that the	38
significantly associated with	38
patients with the	37
after icu admission	37
changes in the	37
of acute kidney	37
critically ill patient	37
of influenza a	37
chronic health evaluation	37
was used for	37
in the lungs	37
world health organization	37
and intensive care	37
mechanical ventilation in	37
the introduction of	37
in comparison with	37
were observed in	37
polymerase chain reaction	37
depending on the	37
care unit patients	37
the corresponding author	37
to improve the	37
retrospective analysis of	37
patients with influenza	37
a diagnosis of	37
studies are needed	37
with influenza a	37
difference in the	37
retrospective observational study	36
patients with aki	36
and outcome of	36
in of patients	36
defi cient mice	36
hospital mortality was	36
had a higher	36
into two groups	36
the application of	36
assessment of the	36
were significantly higher	36
than that of	36
when compared to	36
was the most	36
the implementation of	36
icu stay and	36
significant differences in	36
the outcome of	36
was significantly lower	36
from patients with	36
are available from	36
used as a	36
the potential to	36
critically ill adults	36
for each patient	36
half of the	36
from the icu	36
mortality in critically	36
to identify the	36
differences in the	36
to patients with	35
independent risk factor	35
lower in the	35
was carried out	35
defined as the	35
the cause of	35
for all patients	35
and after the	35
the most important	35
from the corresponding	35
with a higher	35
be considered in	35
of mortality in	35
who were admitted	35
standard of care	35
at risk of	35
between patients with	35
the mean age	35
medical intensive care	35
the association of	35
the setting of	35
of patients in	35
the other hand	35
no significant differences	35
the critical care	34
likely to be	34
for at least	34
icu admission and	34
with coronavirus disease	34
observed in the	34
evaluation of the	34
more than one	34
needs to be	34
with sepsis and	34
is an important	34
eff ect of	34
clinical course and	34
compared to patients	34
logistic regression analysis	34
multiple organ dysfunction	34
of the virus	34
has been associated	34
the area under	34
survivors and non	34
defined by the	34
aim of our	34
none of the	34
defined as a	33
receiver operating characteristic	33
of lung injury	33
and critical care	33
the fact that	33
based on a	33
were collected from	33
seems to be	33
studies have shown	33
the patients who	33
the study and	33
enrolled in the	33
hospital mortality in	33
in the setting	33
test was used	33
a result of	33
guidelines for the	33
in this population	33
in patients admitted	33
was found to	33
years of age	33
that can be	33
was present in	33
the day of	33
respiratory failure in	33
more than hours	33
a history of	33
cohort of patients	33
was performed to	33
a retrospective analysis	33
of icu patients	33
this is the	33
blood samples were	33
a prospective cohort	33
and severity of	32
such as the	32
did not have	32
the time to	32
in the analysis	32
of coronavirus disease	32
be used as	32
have been reported	32
body mass index	32
surviving sepsis campaign	32
stay in the	32
requiring mechanical ventilation	32
in clinical practice	32
shown in fig	32
the cuff leak	32
pao fio ratio	32
were performed using	32
understanding of the	32
the amount of	32
to intensive care	32
with a high	32
was found between	32
in a large	32
admitted to a	32
and treatment of	32
considered to be	32
study are available	31
and duration of	31
in the group	31
from mechanical ventilation	31
are expressed as	31
the influence of	31
of the two	31
a retrospective observational	31
intensive care patients	31
influenza a viruses	31
during the current	31
in ards patients	31
a role in	31
included in this	31
acquired pneumonia in	31
of stay was	31
in the acute	31
between january and	31
acute physiology score	31
for treatment of	31
the start of	31
at risk for	31
risk of developing	31
of patients had	31
the ability of	31
a randomized controlled	31
is the most	31
of organ dysfunction	31
sepsis or septic	31
in the dex	30
an independent risk	30
statistically signifi cant	30
were more likely	30
the assessment of	30
influenza a h	30
of patients infected	30
likely to have	30
included patients with	30
extubation airway obstruction	30
ill patients in	30
be due to	30
society of intensive	30
some of the	30
appears to be	30
our aim was	30
diffuse alveolar damage	30
when compared with	30
it is not	30
with or without	30
it may be	30
may contribute to	30
is to evaluate	30
patients at risk	30
characteristics of the	30
in acute lung	30
a marker of	30
used to assess	30
diff erence in	30
statistical analysis was	30
an increase of	30
use of a	30
in this group	30
design of the	30
of the present	30
characteristics and outcomes	30
in the hospital	30
an intensive care	30
central nervous system	30
death in the	29
for the diagnosis	29
of acute lung	29
all patients with	29
we compared the	29
materials not applicable	29
is the first	29
with hospital mortality	29
and should be	29
intensive care and	29
in our cohort	29
to determine whether	29
in a prospective	29
of sepsis and	29
higher risk of	29
the intervention group	29
of stay and	29
the percentage of	29
patients with confirmed	29
with an increased	29
levels in the	29
and materials not	29
of hospitalized patients	29
clinical features of	29
shown to be	29
the icu stay	29
severe respiratory failure	29
the hfnc group	29
in the pathogenesis	29
for disease control	29
was signifi cantly	29
to our icu	29
of novel coronavirus	29
organ failure and	29
risk of bias	29
mortality rate of	29
the accuracy of	29
a predictor of	29
in relation to	29
was lower in	29
in of cases	29
effect on the	28
large number of	28
significantly higher than	28
in mainland china	28
it is possible	28
further studies are	28
a and b	28
and risk factors	28
we sought to	28
ventilated patients with	28
group and in	28
were higher in	28
on reasonable request	28
incidence of delirium	28
corresponding author on	28
that patients with	28
were found to	28
defi ned as	28
the receiver operating	28
responsible for the	28
use of the	28
remains to be	28
risk factors of	28
in line with	28
of patients and	28
in our icu	28
mean age of	28
role of the	28
institutional affiliations we	28
divided into two	28
inflammatory response syndrome	28
society of america	28
on the day	28
we evaluated the	28
patients with an	28
the niv group	28
could not be	28
observational study of	28
was to compare	27
was an independent	27
continuous renal replacement	27
were randomized to	27
severity of disease	27
are required to	27
positive airway pressure	27
in animal models	27
patients who did	27
simplified acute physiology	27
in the presence	27
in a tertiary	27
of the covid	27
objective was to	27
in comparison to	27
the effectiveness of	27
on admission to	27
exclusion criteria were	27
whitney u test	27
the production of	27
in those with	27
patients with nva	27
lung injury in	27
inclusion criteria were	27
in patients receiving	27
samples were collected	27
for management of	27
significantly lower in	27
the ability to	27
and clinical characteristics	27
higher than the	27
supported by the	27
between survivors and	27
had at least	27
data from the	27
higher than that	27
secondary outcomes were	27
all patients admitted	27
diagnosis of sepsis	27
to the study	27
resulted in a	27
statistically significant difference	27
the analysis of	27
independent predictor of	26
found that the	26
we would like	26
with a lower	26
patients from the	26
differences between the	26
consent was obtained	26
to the patient	26
and sofa score	26
approval of the	26
of cuff leak	26
we included patients	26
compared with patients	26
moderate to severe	26
the ang tie	26
associated with high	26
significant difference between	26
did not receive	26
a lack of	26
to hospital discharge	26
with mortality in	26
and specificity of	26
data was collected	26
compared with those	26
acute hypoxemic respiratory	26
of extubation failure	26
disease control and	26
the primary endpoint	26
is characterized by	26
were found in	26
ang tie system	26
we observed a	26
were similar in	26
no difference between	26
author on reasonable	26
increase in the	26
pressure support ventilation	26
been reported to	26
influenza virus infection	26
that of the	26
analysis of a	26
of at least	26
the h n	26
pandemic h n	26
contribute to the	26
the decision to	26
control and prevention	26
mechanical ventilation was	26
no statistically significant	26
coronary artery bypass	26
patients with elevated	25
as shown in	25
serum levels of	25
no differences in	25
associated with hospital	25
majority of patients	25
among the patients	25
lead to a	25
a signifi cant	25
patients with novel	25
in contrast to	25
in the hfnc	25
prognostic value of	25
for mechanical ventilation	25
impact on the	25
under the curve	25
interpretation of the	25
of the work	25
drafted the manuscript	25
a randomized clinical	25
with severe acute	25
patients with cap	25
management of severe	25
clinical practice guidelines	25
causes of death	25
a cohort of	25
each of the	25
the endotracheal tube	25
cant diff erence	25
more than of	25
a combination of	25
results a total	25
we assessed the	25
and clinical outcomes	25
study aimed to	25
and those with	25
signifi cantly higher	25
withdrawal of life	25
to examine the	25
written informed consent	25
a study of	25
common cause of	25
of h n	25
quality of evidence	25
not significantly different	25
of a new	25
the statistical analysis	25
there are no	25
patients with coronavirus	25
we used the	25
prolonged mechanical ventilation	25
mortality and morbidity	25
and mechanical ventilation	25
to be the	25
obtained from the	25
an independent predictor	25
in the upper	24
or analyzed during	24
hours of icu	24
found in the	24
in the intervention	24
during the icu	24
in the two	24
during critical illness	24
the icu is	24
to the development	24
in icu and	24
may be more	24
paper at https	24
due to a	24
for critical care	24
mortality rate in	24
can also be	24
up to days	24
the change in	24
the distribution of	24
prior to the	24
safety and efficacy	24
institutional review board	24
under the receiver	24
abdominal compartment syndrome	24
a median of	24
were excluded from	24
performed using the	24
with a mean	24
in the uk	24
the risk factors	24
is a major	24
day mortality in	24
used to compare	24
and the presence	24
the sofa score	24
an increased risk	24
of respiratory failure	24
all of the	24
upper respiratory tract	24
respiratory failure and	24
significant increase in	24
correlated with the	24
systematic review of	24
did not show	24
levels of il	24
was considered statistically	24
accompanies this paper	24
patients at high	24
in of the	24
was used in	24
data suggest that	24
during icu stay	24
this paper at	24
of the respiratory	24
mechanical ventilation with	24
american thoracic society	24
any of the	24
independent risk factors	24
to be associated	24
and interpretation of	24
supplementary information accompanies	24
the survival rate	24
stay in icu	24
were compared with	24
information accompanies this	24
outcomes in patients	24
the icu with	24
predictive value of	24
current study are	24
the respiratory tract	24
predictor of mortality	23
in the niv	23
day mortality rate	23
ethics committee of	23
in the clinical	23
characteristics of patients	23
like to thank	23
patients included in	23
at baseline and	23
a pilot study	23
is needed to	23
version of the	23
were as follows	23
the immune response	23
all the patients	23
of antibiotic therapy	23
risk factors associated	23
results of a	23
an important role	23
at the bedside	23
outcomes of critically	23
in the future	23
the design of	23
the ethics committee	23
its impact on	23
logistic regression model	23
diseases society of	23
activation of the	23
infectious diseases society	23
data were analyzed	23
group than in	23
for this study	23
and is associated	23
to identify patients	23
and the risk	23
ill patients and	23
wide range of	23
the final version	23
the authors read	23
to study the	23
quality of care	23
the study protocol	23
with a median	23
on mechanical ventilation	23
considered statistically significant	23
in a study	23
and management of	23
central venous catheter	23
disseminated intravascular coagulation	23
membrane oxygenation for	23
novel coronavirus pneumonia	23
the eff ect	23
caused by the	23
h n pdm	23
in severe covid	23
the basis of	23
are presented in	23
in the fi	23
little is known	23
with the use	23
cohort study of	23
as soon as	23
results of this	23
the addition of	23
extracorporeal life support	23
is based on	23
the dex group	23
was performed by	23
during the covid	23
the inclusion criteria	23
hours of admission	23
is likely to	22
was supported by	22
pneumonia in the	22
reduce the incidence	22
and the use	22
died in the	22
were able to	22
multivariate logistic regression	22
on icu admission	22
was assessed using	22
known to be	22
death in patients	22
on the contrary	22
high flow nasal	22
infl ammatory response	22
acute myocardial infarction	22
independent predictors of	22
similar in both	22
on the basis	22
these patients were	22
associated with acute	22
was defi ned	22
critical care services	22
in the aci	22
an association between	22
risk of mortality	22
the beginning of	22
in the nva	22
outcome in patients	22
was based on	22
and can be	22
of delirium in	22
the most severe	22
may be associated	22
to be an	22
was assessed by	22
to understand the	22
not differ between	22
among critically ill	22
patients in group	22
a significant decrease	22
the evolution of	22
red blood cells	22
in patients in	22
institutional affiliations the	22
nature of the	22
of sepsis in	22
risk factors and	22
of the cases	22
by the institutional	22
after icu discharge	22
observational cohort study	22
the case of	22
subgroup of patients	22
were performed in	22
a large number	22
first h of	22
with poor outcome	22
diagnosis and treatment	22
associated with severe	22
been reported in	22
a group of	22
distress syndrome in	22
median age was	22
increase the risk	22
of the icu	22
in the last	22
be able to	22
at admission and	22
the potential for	22
higher levels of	22
the detection of	22
the first day	21
the study design	21
on the first	21
viral load in	21
we found a	21
we investigated the	21
be related to	21
h n virus	21
of the included	21
care in the	21
this study aimed	21
study showed that	21
treatment of severe	21
after adjustment for	21
in severe sepsis	21
in cases of	21
the world health	21
severe traumatic brain	21
were no significant	21
in this retrospective	21
the median time	21
and hospital length	21
the feasibility of	21
in children with	21
the icu for	21
ventilation with heliox	21
and may be	21
day mortality was	21
in patients without	21
is common in	21
risk of bleeding	21
return of spontaneous	21
compared to those	21
in a patient	21
addition to the	21
was determined by	21
has been demonstrated	21
severe disease icu	21
observational study was	21
was seen in	21
the safety of	21
the median age	21
may result in	21
the efficacy and	21
were compared using	21
this retrospective study	21
of cardiac arrest	21
we used a	21
of spontaneous circulation	21
was higher than	21
critical care unit	21
h n infection	21
pneumonia in adults	21
severe sepsis or	21
the lower respiratory	21
severity of the	21
a wide range	21
has also been	21
correlation between the	21
a recent study	21
centers for disease	21
critically ill covid	21
the type of	21
higher rate of	21
those who did	21
used for the	21
a high risk	21
to critical care	21
a significant difference	21
of avian influenza	21
used to evaluate	21
the most commonly	21
at hospital discharge	21
is known about	21
the result of	21
randomised controlled trial	21
kidney injury in	21
patients who developed	21
present study was	21
in the severe	21
should be used	21
see additional file	21
all patients who	21
were defined as	21
but not in	21
to test the	21
the patient was	21
writing of the	21
viral shedding in	21
those in the	21
lung infl ammation	21
especially in the	21
were classified as	20
of ml kg	20
patients with respiratory	20
days in the	20
response to the	20
reported to be	20
the combination of	20
the timing of	20
strongly associated with	20
our study is	20
for patients who	20
the difference between	20
this study are	20
on the icu	20
ranging from to	20
the emergency room	20
as a predictor	20
a statistically significant	20
analyzed during the	20
a reduction of	20
management of patients	20
european society of	20
observed in patients	20
with acute lung	20
outcome was the	20
a university hospital	20
exhaled air dispersion	20
reported in the	20
hypercapnic respiratory failure	20
higher incidence of	20
of the treatment	20
important role in	20
apache ii scores	20
designed the study	20
therapy in the	20
course of the	20
discharge from the	20
blood oxygen desaturation	20
the evaluation of	20
patients hospitalized with	20
study aims to	20
accordance with the	20
novel coronavirus in	20
a sensitivity of	20
days after the	20
infected with sars	20
the incidence and	20
were measured using	20
was detected in	20
onset atrial fibrillation	20
primary endpoint was	20
hpai h n	20
positive fluid balance	20
during their icu	20
first hours of	20
eff ects of	20
eff ect on	20
diff erences in	20
may be the	20
the prognosis of	20
glasgow coma scale	20
the extent of	20
ml kg min	20
most common cause	20
for septic shock	20
the aci group	20
the value of	20
the prevention of	20
the data and	20
to the emergency	20
the correlation between	20
of a novel	20
data are expressed	20
was a significant	20
related organ failure	20
consent was waived	20
are likely to	20
in adults with	20
according to a	20
has been used	20
health care workers	20
with respiratory failure	20
in the subgroup	20
treatment of influenza	20
hospital mortality rate	20
in the respiratory	20
and sofa scores	20
are presented as	20
animal models of	20
in all cases	20
median age of	20
a p value	19
of a tertiary	19
the response to	19
led to a	19
by the ethics	19
affiliations the authors	19
results suggest that	19
the hypothesis that	19
play a role	19
in the development	19
may also be	19
the lung microbiome	19
fraction of inspired	19
in the same	19
virus infection in	19
which may be	19
their icu stay	19
were randomly assigned	19
the increase of	19
relationship between the	19
the initiation of	19
be explained by	19
patients with infection	19
dead space fraction	19
the characteristics of	19
a patient with	19
in the placebo	19
evaluate the impact	19
and efficacy of	19
the spread of	19
of cases of	19
cardiac surgery patients	19
of inspired oxygen	19
children with acute	19
primary and secondary	19
in this cohort	19
several studies have	19
patients in whom	19
the icu of	19
yet to be	19
is shown in	19
in the critical	19
respiratory tract infection	19
sepsis in the	19
the subgroup of	19
by means of	19
critically ill children	19
in the patients	19
performed a retrospective	19
in hong kong	19
the pathophysiology of	19
study was performed	19
in the literature	19
a period of	19
arterial blood gas	19
the aim was	19
patients were excluded	19
the acute phase	19
mild and severe	19
explained by the	19
in additional file	19
our intensive care	19
in which the	19
in the case	19
after adjusting for	19
not able to	19
of extracorporeal membrane	19
was performed on	19
have been shown	19
to our knowledge	19
value of the	19
the placebo group	19
to be determined	19
we could not	19
over the first	19
was not significantly	19
high risk for	19
spontaneous breathing trial	19
of patients was	19
in the medical	19
a dose of	19
negative predictive value	19
from septic shock	19
has been suggested	19
the patients in	19
duration of mv	19
there was an	19
to confirm the	19
is not a	18
and to determine	18
were used for	18
that the use	18
statistical analyses were	18
had significantly higher	18
and associated with	18
guidelines for management	18
lower in patients	18
low levels of	18
tended to be	18
patients hospitalized in	18
defined according to	18
were measured at	18
of nebulised heparin	18
the immune system	18
that in the	18
previous studies have	18
of corticosteroids in	18
excluded from the	18
respiratory tract infections	18
due to its	18
small sample size	18
admission to icu	18
soon as possible	18
groups of patients	18
the concentration of	18
the manuscript and	18
ideal body weight	18
retrospective study of	18
critical illness and	18
revised the manuscript	18
is related to	18
for intensive care	18
and did not	18
and icu mortality	18
of the total	18
and hours after	18
is to assess	18
care units in	18
with higher mortality	18
study of the	18
and those who	18
the criteria for	18
multivariable logistic regression	18
of the medical	18
patients were classified	18
the inflammatory response	18
the respiratory system	18
patients with high	18
affiliations not applicable	18
significantly lower than	18
high levels of	18
to investigate whether	18
correlation was found	18
patients were treated	18
for the first	18
endothelial growth factor	18
were signifi cantly	18
a higher risk	18
in sepsis and	18
shown in figure	18
adult critically ill	18
in the past	18
requiring icu admission	18
and patients were	18
diff erence between	18
may have been	18
of a large	18
as a consequence	18
the datasets used	18
mobility group box	18
aimed to investigate	18
the data analysis	18
a significant increase	18
first day of	18
over time in	18
clinical outcomes in	18
to predict the	18
nasal cannula oxygen	18
ml kg of	18
was calculated using	18
the risk for	18
the burden of	18
were analyzed by	18
empirical antimicrobial therapy	18
patients with chronic	18
was independently associated	18
significant decrease in	18
a review of	18
aimed to evaluate	18
pneumonia caused by	18
of the pandemic	18
the release of	18
sofa score was	18
ill medical patients	18
ill patients who	18
a case report	18
analysis showed that	18
in the multivariate	18
were analyzed using	18
los in icu	18
institutional affiliations not	18
of life support	18
with severe cap	18
version to be	18
higher than in	18
to be published	18
of the immune	18
and for the	18
were the most	18
result in a	18
rate in the	18
at least hours	18
conventional oxygen therapy	18
by using the	18
the performance of	18
difference in mortality	18
for icu admission	18
icu mortality was	18
coronavirus disease in	18
neuromuscular blocking agents	18
were obtained from	18
and the median	18
a tertiary care	18
course and outcomes	18
conception and design	18
vascular endothelial growth	18
to the hospital	18
for the development	18
up to of	18
sofa score at	18
with high mortality	18
did not find	18
of influenza in	18
introduction of the	18
society of critical	18
days after admission	17
also associated with	17
is not possible	17
was performed with	17
on the management	17
final approval of	17
from the patient	17
cardiac arrest patients	17
all patients had	17
two groups were	17
the institutional review	17
of the cuff	17
were identifi ed	17
of the current	17
the proportions of	17
novel influenza a	17
primary cause of	17
patients admitted in	17
undergoing cardiac surgery	17
of spontaneous breathing	17
fluid resuscitation rate	17
did not affect	17
may have a	17
in recent years	17
critical care units	17
the possibility of	17
signs and symptoms	17
these patients had	17
had significantly lower	17
with a low	17
predictors of mortality	17
we found no	17
the normal range	17
admitted to intensive	17
of corticosteroid treatment	17
a mean age	17
was to describe	17
with a significant	17
a consequence of	17
to analyze the	17
serious adverse events	17
is essential to	17
red blood cell	17
severely ill patients	17
and hospital stay	17
in the cohort	17
confusion assessment method	17
severe disease non	17
mv with heliox	17
within hours after	17
in the data	17
of them were	17
a single ventilator	17
in patients at	17
of patients undergoing	17
receiving mechanical ventilation	17
lower than that	17
adult patients admitted	17
used to determine	17
is involved in	17
age was years	17
pressure of arterial	17
under the roc	17
to estimate the	17
the european society	17
health evaluation ii	17
in those who	17
during the pandemic	17
ministry of health	17
for up to	17
and there was	17
used to identify	17
leading cause of	17
during the influenza	17
is defined as	17
are summarized in	17
in this setting	17
baseline characteristics and	17
there may be	17
systolic blood pressure	17
were no differences	17
of less than	17
initial fluid resuscitation	17
risk of extubation	17
in the human	17
well as in	17
patients with community	17
patients who required	17
of the pulmonary	17
with a diagnosis	17
all patients received	17
longer duration of	17
in each group	17
throughout the study	17
the emergence of	17
treatment of acute	17
with severe ards	17
data on the	17
and at the	17
n influenza in	17
of the first	17
delirium in the	17
with severe influenza	17
we aim to	17
and multiple organ	17
randomly assigned to	17
to measure the	17
in the final	17
and it is	17
associated with worse	17
did not change	17
our understanding of	17
patients who met	17
coronavirus in wuhan	17
severe forms of	17
the availability of	17
at hospital admission	17
mortality was higher	17
of hospital mortality	17
a control group	17
accuracy of the	17
are known to	17
has led to	17
that it is	17
within days of	17
the version to	17
white blood cell	17
out of the	17
in the restrictive	17
presented in table	17
american college of	17
of the brain	17
in patients treated	17
at t and	17
on the use	17
in the design	17
study in a	17
of the diaphragm	17
and outcome in	17
patients with low	17
mechanical ventilation for	17
associated with survival	17
an analysis of	17
the likelihood of	17
cardiac arrest and	16
cm h o	16
the lungs of	16
mortality at days	16
arterial blood pressure	16
and the number	16
the safety and	16
author details key	16
immune response to	16
committee of the	16
during the h	16
data collection and	16
the intensity of	16
the care of	16
to increase the	16
within days after	16
the central nervous	16
of patients at	16
of the following	16
high mortality rate	16
the pao fio	16
development of a	16
to the lung	16
is used to	16
in a recent	16
of ards patients	16
early detection of	16
patients and their	16
post hoc analysis	16
bronchoalveolar lavage fluid	16
in the number	16
distress syndrome and	16
care and emergency	16
were responsible for	16
aspects of the	16
similar to the	16
a higher mortality	16
of the critically	16
clinical and laboratory	16
features of patients	16
critically ill medical	16
small number of	16
expressed as mean	16
patients with ali	16
appeared to be	16
our study has	16
total number of	16
charlson comorbidity index	16
and has been	16
this systematic review	16
have also been	16
validation of the	16
it should be	16
of renal replacement	16
and the acute	16
ii score was	16
suggest that the	16
ml cmh o	16
the reduction of	16
is required to	16
did not significantly	16
this study aims	16
day of icu	16
of the clinical	16
a cardiac arrest	16
and organ failure	16
do not have	16
arterial partial pressure	16
tidal volume of	16
the data were	16
appear to be	16
h and h	16
cumulative fluid balance	16
the concept of	16
have not been	16
enrolled in this	16
the conception and	16
of treatment failure	16
all adult patients	16
were used in	16
interpretation of data	16
n influenza a	16
h n pandemic	16
is necessary to	16
factors for mortality	16
mortality in sepsis	16
no effect on	16
of death and	16
and mechanically ventilated	16
the univariate analysis	16
plasma levels of	16
admitted to icus	16
characteristics of hospitalized	16
was defined by	16
fi rst hours	16
may be useful	16
need for mechanical	16
the ratio of	16
can be found	16
the icu was	16
in those patients	16
significantly different between	16
as the primary	16
the need to	16
as a potential	16
of each patient	16
patients undergoing cardiac	16
of middle east	16
associated with better	16
and emergency medicine	16
sepsis septic shock	16
during ecmo support	16
requiring intensive care	16
been used in	16
cd t cells	16
that there is	16
the progression of	16
and in patients	16
infected pneumonia in	16
was measured by	16
infection control measures	16
is a retrospective	16
a tertiary hospital	16
an influenza pandemic	16
was calculated for	16
of which were	16
the influenza a	16
of admission to	16
main cause of	16
to be higher	16
in some patients	16
is possible that	16
different between the	16
of the version	16
positive pressure ventilation	16
patients presenting with	16
the heterogeneity of	16
of severe disease	16
for these patients	16
as assessed by	16
the main cause	16
and respiratory failure	16
to participate in	16
return to work	16
have been found	16
to determine if	16
may help to	16
in the event	16
patients treated in	16
and use of	16
hospitalized in the	16
patients who survived	15
those patients who	15
and the incidence	15
this is in	15
be an important	15
in the second	15
f i o	15
apache ii and	15
this study we	15
as previously described	15
use of corticosteroids	15
the increase in	15
for the use	15
in icu was	15
a randomized trial	15
acute ischemic stroke	15
was in the	15
the reliability of	15
mean duration of	15
continuous variables were	15
in the covid	15
patients have been	15
the formation of	15
comparison with the	15
of central venous	15
and increased mortality	15
hoc analysis of	15
final version of	15
cant diff erences	15
signifi cantly lower	15
medical and surgical	15
the gold standard	15
method for the	15
been described in	15
with viral pneumonia	15
significant improvement in	15
an average of	15
were independently associated	15
is an independent	15
work of breathing	15
the data collection	15
has been proposed	15
levels of the	15
of the european	15
a previous study	15
was used as	15
with pandemic influenza	15
january to december	15
with the development	15
the event of	15
decrease in the	15
a series of	15
was responsible for	15
on mortality in	15
this suggests that	15
the syndromic rm	15
was significantly associated	15
are consistent with	15
the frequency of	15
of the drug	15
the novel coronavirus	15
to explore the	15
hospital mortality among	15
patients with cardiac	15
in obese patients	15
more than days	15
in the usa	15
of evidence for	15
the rrt group	15
for the study	15
statistically significant differences	15
within h of	15
dose of mg	15
median duration of	15
observational study in	15
of the same	15
is supported by	15
it is a	15
ranged from to	15
with stage aki	15
measurements were performed	15
are the most	15
the included studies	15
in the current	15
to develop a	15
patients were analyzed	15
not statistically significant	15
the probability of	15
electronic health record	15
significant reduction in	15
randomized to receive	15
was shown to	15
part of a	15
high rate of	15
the cci group	15
was not statistically	15
and apache ii	15
patients with noaf	15
of corticosteroids on	15
with the severity	15
guidelines on the	15
early identification of	15
patients with viral	15
of alveolar macrophages	15
to the berlin	15
the icu in	15
duration of ventilation	15
infl ammation and	15
increases the risk	15
outcome of patients	15
mouse model of	15
the sars outbreak	15
infected with novel	15
no diff erence	15
critical illness in	15
management of the	15
datasets used and	15
a case series	15
carried out in	15
severe h n	15
was calculated as	15
number of cases	15
in light of	15
a model of	15
was a retrospective	15
management of covid	15
coronary artery disease	15
point of care	15
but did not	15
study has several	15
this work was	15
with a decrease	15
was lower than	15
at any time	15
pressure of oxygen	15
patients during the	15
blunt chest trauma	15
after discharge from	15
cystic fi brosis	15
between noaf and	15
the severe disease	15
septic shock in	15
a virus infection	15
airway epithelial cells	15
clinical features and	15
positive predictive value	15
it can be	15
is a frequent	15
the identification of	15
viral load and	15
of organ failure	15
for respiratory failure	15
study in patients	15
low risk of	15
the upper respiratory	15
care unit admission	15
mortality associated with	15
mean length of	15
the lung and	15
reliability of the	15
the roc curve	15
of the microbiome	15
than half of	15
and had a	15
studies have reported	15
of polymicrobial aetiology	15
associated with improved	15
low tidal volume	15
on the incidence	15
with confirmed covid	15
for severe acute	15
fl uid balance	15
diagnostic accuracy of	15
methods a retrospective	15
january and december	15
the patients had	15
of invasive mechanical	15
local ethics committee	15
in a cohort	15
further research is	15
there has been	15
is known to	15
randomized controlled study	15
of the acute	15
a descriptive study	15
within h after	15
reduction in mortality	15
in patients on	15
t and t	15
a significant improvement	15
a significant reduction	15
between april and	15
in a single	15
high incidence of	15
implementation of the	15
at least two	15
to of patients	14
first days of	14
a clinical trial	14
cytokines and chemokines	14
after the first	14
the university of	14
oxygenation for severe	14
safe and effective	14
with suspected infection	14
for sepsis and	14
that of patients	14
blood cell count	14
the differences in	14
of cmv reactivation	14
function of the	14
patients admitted with	14
associated pneumonia in	14
a high mortality	14
has been described	14
respiratory support methods	14
and design of	14
is significantly higher	14
were diagnosed with	14
level in the	14
were performed on	14
a longer duration	14
the magnitude of	14
have been described	14
increased levels of	14
physicians and nurses	14
h n inoculation	14
after h n	14
and mortality of	14
the sensitivity of	14
spontaneous breathing trials	14
pneumocystis carinii pneumonia	14
and risk of	14
hospital mortality and	14
there is an	14
diff erences between	14
propensity score matching	14
the outbreak of	14
serve as a	14
patients requiring mechanical	14
septic patients with	14
is a risk	14
study conducted in	14
outcomes in critically	14
of pandemic influenza	14
patients may be	14
pathological findings of	14
personal protective equipment	14
the study group	14
in both the	14
patients in intensive	14
for ali ards	14
recent studies have	14
reduction in the	14
patients with pandemic	14
of the major	14
nasal cannula in	14
as a risk	14
to assess whether	14
for the prevention	14
a negative correlation	14
influenza in the	14
of prone positioning	14
adult intensive care	14
conducted a retrospective	14
icu of a	14
organ system dysfunction	14
calculated as the	14
use of mechanical	14
start of the	14
not be used	14
to guide the	14
in the general	14
the most effective	14
a post hoc	14
in the cci	14
out of patients	14
reduce the risk	14
information on the	14
the multivariate analysis	14
of the left	14
the nature of	14
critical care physicians	14
implementation of a	14
are reported in	14
cannula oxygen therapy	14
was given to	14
and of the	14
risk factors were	14
is independently associated	14
performed in the	14
associated with lower	14
patients according to	14
was to identify	14
ill patients is	14
onset of symptoms	14
in severe acute	14
cases of covid	14
conducted a prospective	14
comparison of the	14
pupillary light reflex	14
during extracorporeal membrane	14
and exclusion criteria	14
with pneumonia in	14
icu due to	14
the surface of	14
leak test for	14
left and right	14
we calculated the	14
to support the	14
patients were not	14
in the course	14
should be taken	14
have been proposed	14
is consistent with	14
should also be	14
showed a significant	14
to decrease the	14
institutional affiliations none	14
to be more	14
critical care resources	14
which is a	14
in older patients	14
risk of severe	14
identifi cation of	14
the choice of	14
the first time	14
of multiple organ	14
occurred in patients	14
wrote the manuscript	14
to an increase	14
the patient and	14
epidemiological and clinical	14
flow oxygen therapy	14
of aki in	14
an improvement in	14
study was the	14
the manuscript for	14
data in the	14
electronic medical records	14
community acquired pneumonia	14
assessed using the	14
associated with prolonged	14
partial thromboplastin time	14
was evaluated by	14
patients in a	14
demographic and clinical	14
age of the	14
common risk factors	14
duration of antibiotic	14
during the period	14
icu admission was	14
was divided into	14
the delivery of	14
septic shock is	14
therapy in patients	14
the prognostic value	14
weaning from mechanical	14
we hypothesize that	14
were compared between	14
at the beginning	14
we excluded patients	14
pneumonia in patients	14
of this article	14
was evaluated using	14
are included in	14
of the respondents	14
a critical care	14
immune responses in	14
effect of mechanical	14
subset of patients	14
more than half	14
for severe sepsis	14
percentage of patients	14
a population of	14
association between the	14
pp during ecmo	14
be used in	14
of the gut	14
in more than	14
samples were taken	14
group and the	14
levels were significantly	14
patients with moderate	14
high mobility group	14
increased mortality in	14
performed using a	14
in elderly patients	14
venous oxygen saturation	14
an impact on	14
and icu length	14
a mouse model	14
impact of a	14
the first week	14
in the univariate	14
was able to	14
to icu admission	14
an observational study	14
at increased risk	14
it is associated	14
may explain the	14
in the brain	14
hours after the	14
the study is	14
at h after	14
clinical characteristics and	14
patients were identified	14
the overall mortality	14
with that of	14
this may be	14
we developed a	14
determined by the	14
poor neurological outcome	14
of care and	14
was assessed with	14
two or more	14
collected from the	14
and the time	14
group compared to	14
on the outcome	14
expiratory lung volume	14
in h n	14
treated in the	14
use in the	14
in the adult	14
blood gas analysis	14
of severe covid	14
cells of the	14
metabolites in the	14
evidence suggests that	14
inclusion and exclusion	14
injury and the	14
the prowess trial	13
the icu are	13
should be avoided	13
the tidal volume	13
have been associated	13
mcg kg min	13
of the non	13
could be a	13
resistant staphylococcus aureus	13
between patients who	13
could be an	13
could result in	13
venous extracorporeal membrane	13
could be used	13
variables were compared	13
disease icu group	13
the requirement for	13
predicted body weight	13
to quantify the	13
for the primary	13
and death in	13
mortality among patients	13
of the time	13
contact with the	13
requiring renal replacement	13
secondary outcomes included	13
blood fl ow	13
a subset of	13
on clinical outcomes	13
has several limitations	13
as adjunctive therapy	13
for a total	13
between june and	13
from march to	13
importance of the	13
and h after	13
depends on the	13
the eff ects	13
the process of	13
of chronic obstructive	13
regression analysis was	13
the mechanisms of	13
group compared with	13
patients suffering from	13
study reported that	13
during the same	13
were expressed as	13
days of admission	13
and the mean	13
was compared with	13
number of days	13
with severe disease	13
cap caused by	13
the local ethics	13
working group on	13
the prediction of	13
than those in	13
more common in	13
more frequent in	13
blood pressure and	13
stage renal disease	13
as an alternative	13
may be due	13
this is an	13
this was not	13
after admission to	13
of death were	13
in our institution	13
were not significantly	13
high level of	13
all authors contributed	13
international guidelines for	13
caused by a	13
was a single	13
studies are required	13
well as a	13
impact of the	13
in the prowess	13
than patients with	13
in patients requiring	13
introduction of a	13
is considered to	13
could lead to	13
that has been	13
deep vein thrombosis	13
the gut microbiome	13
influenza h n	13
were similar to	13
with sepsis were	13
plasma concentrations of	13
and wrote the	13
our objective was	13
were mechanically ventilated	13
who died in	13
evidence to support	13
aimed to assess	13
after hospital discharge	13
time course of	13
who received ecmo	13
pulmonary blood flow	13
were not different	13
the coronavirus disease	13
this study were	13
patients with lung	13
variables associated with	13
the comparison of	13
it was not	13
deposition in the	13
as a marker	13
in the time	13
who met the	13
with suspected influenza	13
but there was	13
be a useful	13
inflammatory response to	13
significant differences were	13
and an increase	13
prone positioning in	13
methods a prospective	13
interstitial lung disease	13
not different between	13
levels were measured	13
by the local	13
findings suggest that	13
mortality rates in	13
the size of	13
patients with cs	13
patients with vap	13
was due to	13
in an icu	13
h n v	13
all authors have	13
with previous studies	13
fluid balance in	13
used as an	13
measurement of the	13
alveolar dead space	13
of cardiac injury	13
tertiary care hospital	13
measured at the	13
primary influenza pneumonia	13
data were recorded	13
of observational studies	13
in the lower	13
on patients with	13
with a total	13
effects of corticosteroids	13
similar to those	13
regardless of the	13
of adult patients	13
the etiology of	13
of the protocol	13
assess the effect	13
septic shock was	13
analysis was used	13
of the whole	13
this study has	13
of mdr pathogens	13
those patients with	13
affiliations we would	13
host response to	13
it is also	13
qualitative and quantitative	13
disease in china	13
the authors thank	13
consistent with the	13
due to their	13
a higher incidence	13
response to treatment	13
the prone position	13
macrophage activation syndrome	13
from critical care	13
during the course	13
in group a	13
due to acute	13
injury severity score	13
the attending physician	13
the surviving sepsis	13
leading to the	13
in a rat	13
mechanically ventilated infants	13
response to infection	13