Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-001894-ptuelrqjICU- Acquired Pneumonia Study Group De- escalation therapy: is it valuable for the management of ventilator- associated pneumonia?
cord-001322-7xmxcm35when does it happen, and do systemic inflammatory response syndrome criteria help predict course?
cord-000086-bnkbwh3wLung mechanics in normal infants and infants with congenital heart disease Lung mechanics in infants with left- toright shunt congenital heart disease Is bronchiolitis an obsolete term?
cord-001473-aki28lhpThe acute respiratory distress syndrome Acute respiratory distress syndrome Epidemiology and outcomes of acute lung injury Incidence and outcomes of acute lung injury Has mortality from acute respiratory distress syndrome decreased over time?
cord-001661-dj9bxhwbAn early PEEP/ FiO2 trial identifies different degrees of lung injury in patients with acute respiratory distress syndrome Acute respiratory distress syndrome 40 years later: time to revisit its definition Are we able to optimize the definition and diagnosis of severe acute respiratory distress syndrome?
cord-003376-2qi4aibxWhy have clinical trials in sepsis failed?
cord-002240-38aabxh1The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness Association between systemic corticosteroids and outcomes of intensive care unit- acquired pneumonia Prevalence and predictors of corticosteroid- related hyperglycemia in hospitalized patients Hyperglycaemia is associated with poor outcomes in patients admitted to hospital with acute exacerbations of chronic obstructive pulmonary disease Hyperglycaemia as a predictor of outcome during non- invasive ventilation in decompensated COPD Intensive insulin therapy in the critically ill patients Intensive insulin therapy in the medical ICU Glucocorticoid- induced myopathy Paresis acquired in the intensive care unit: a prospective multicenter study Infectious Diseases Society of America/ American Thoracic Society consensus guidelines on the management of community- acquired pneumonia in adults Anti- inflammatory effects of macrolides- an underappreciated benefit in the treatment of community- acquired respiratory tract infections and chronic inflammatory pulmonary conditions?
cord-048449-mzn448zkThe creation of emergency health care standards for catastrophic events Systematic review and economic decision modelling for the prevention and treatment of influenza A and B Managing mass casualties Disaster and mass casualty management in a hospital: How well are we prepared?
cord-004268-raayrjmdThe reliability and validity of ultrasound to quantify muscles in older adults: a systematic review Shear- wave elastography: basic physics and musculoskeletal applications Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function Muscle mass, strength and functional outcomes in critically ill patients after cardiothoracic surgery: does neuromuscular electrical stimulation help?
cord-000161-hxjxczyr2004 update Comparison of two fluid- management strategies in acute lung injury Fluid- management strategies in acute lung injuryliberal, conservative, or both?
cord-000161-hxjxczyrEfficacy and safety of corticosteroids for persistent acute respiratory distress syndrome Confronting an influenza pandemic with inexpensive generic agents: can it be done?
cord-001319-mlkaowqrThe immune response to severe bacterial infections: consequences for therapy Hotchkiss RS: Immunosuppression in patients who die of sepsis and multiple organ failure IgM in microbial infections: taken for granted?
cord-000705-w52dc97hIs there a role for noninvasive ventilation in acute respiratory distress syndrome?
cord-000705-w52dc97ha descriptive study Lactate dehydrogenase leakage as a marker for apoptotic cell degradation induced by influenza virus infection in human fetal membrane cells Should noninvasive ventilation be considered a high- risk procedure during an epidemic?
cord-004147-9bcq3jnmWhy is it so hard to stop doing things that are unwanted, non- beneficial, or unsustainable?
cord-000072-2ygb80scAngiopoietin signalling in critical illness – a future target?
cord-000072-2ygb80scattenuation by dexamethasone Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?
cord-267942-ykl2xy7y: is there any role for communal care when the resources for personalised medicine are exhausted?
cord-003870-hr99dwi7Comparative community burden and severity of seasonal and pandemic influenza: results of the flu watch cohort study The Swine Flu Triage( SwiFT) study: development and ongoing refinement of a triage tool to provide regular information to guide immediate policy and practice for the use of critical care services during the H1N1 swine influenza pandemic Genetics of infectious diseases Targeting the host immune response to fight infection Influenza to target the host?
cord-000492-ec5qzurk: where are we now?
cord-000492-ec5qzurkthe transduction effi ciency of recombinant vectors GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium Spatial and temporal expression of surfactant proteins in hyperoxia- induced neonatal rat lung injury Intrapulmonary TNF gene therapy reverses sepsis- induced suppression of lung antibacterial host defense Clinical Review: Gene- based therapies for ALI/ ARDS: where are we now?
cord-004263-m1ujhhscCan calculation of energy expenditure based on CO2 measurements replace indirect calorimetry?
cord-027526-ohcu28rkCan high- flow nasal cannula reduce the rate of reintubation in adult patients after extubation?
cord-259747-sl9q63ocCOVID-19 pneumonia: ARDS or not?
cord-001536-ta1i0ataThe clinical impact and preventability of ventilator- associated conditions in critically ill patients who are mechanically ventilated Toward improved surveillance: the impact of ventilator- associated complications on length of stay and antibiotic use in patients in intensive care units Implementation of clinical practice guidelines for ventilator- associated pneumonia: a multicenter prospective study Temporal trends of ventilator- associated pneumonia incidence and the effect of implementing health- care bundles in a suburban community Is a strategy based on routine endotracheal cultures the best way to prescribe antibiotics in ventilator- associated pneumonia?
cord-001536-ta1i0ataprospective cohort study Meropenem and piperacillin/ tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/ pharmacodynamic target attainment when extended infusions are used?
cord-003701-i70ztypgInfluenza B hospitalizations are associated with mortality in children Effect of influenza vaccination on the prognosis of hospitalized influenza patients Influenza vaccination modifies disease severity among community- dwelling adults hospitalized with influenza Does influenza vaccination modify influenza severity?
cord-003701-i70ztypginfluenza seasons Estimates of global seasonal influenza- associated respiratory mortality: a modelling study Estimated Influenza Illnesses, Medical Visits, Hospitalizations, and Deaths Averted by Vaccination in the United States Influenza seasonality in the tropics and subtropics-when to vaccinate?
cord-000892-l9862er0Is n't'in order to daily assess the occupancy rate...'better?
cord-000892-l9862er0Réanimation Early corticosteroids in severe influenza A/ H1N1 pneumonia and acute respiratory distress syndrome Can procalcitonin help identify associated bacterial infection in patients with severe influenza pneumonia?
cord-000892-l9862er0novel influenza A( H1N1) virus infection-Mexico Epidemiological and transmissibility analysis of influenza A(H1N1)v in a southern hemisphere setting: Peru Influenza A( H1N1)v in the southern hemisphere- lessons to learn for Europe?
cord-030131-klhg7x8zWhat determines immediate use of invasive ventilation in patients with COPD?
cord-030131-klhg7x8za physiological crossover trial Can high- flow nasal cannula reduce the rate of reintubation in adult patients after extubation?
cord-005503-hm8tvkt3A prospective study Accuracy of Power mode transcranial Doppler in the diagnosis of brain death Standardized care versus precision medicine in the perioperative setting: Can point- of- care testing help bridge the gap?
cord-005503-hm8tvkt3The impact of Bispectral Index monitoring on sedation administration in mechanically ventilated patients Utility of bispectral index in the management of multiple trauma patients Can BIS monitoring be used to assess the depth of propofol anesthesia in the treatment of refractory status epilepticus?
cord-252473-i4pmux28key: cord-252473-i4pmux28 authors: Rogers, Sharon title: Why ca n't I visit?
cord-256237-xiv9vxdpHow much of this is relevant to critical care or to other countries?
cord-001293-dfaxj3bvAre patients with sepsis dying of immune failure-dissecting the arguments used to describe compensatory immunosuppression occurring after sepsis?
cord-001293-dfaxj3bvIs boosting the immune system in sepsis appropriate?
cord-001293-dfaxj3bvauthors: Cavaillon, Jean- Marc; Eisen, Damon; Annane, Djilalli title: Is boosting the immune system in sepsis appropriate?
cord-258087-93yfs7veA second generation human haplotype map of over 3.1 million SNPs What can genome- wide association studies tell us about the genetics of common disease?
cord-258087-93yfs7veWhat makes a good genetic association study?
cord-281663-c2okrt2bCOVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?
cord-278249-vvhq9vgpIs a"cytokine storm"relevant to COVID-19?
cord-278838-qraq5ahoViral infection in patients with severe pneumonia requiring intensive care unit admission Incidence and characteristics of viral community- acquired pneumonia in adults Human metapneumovirus as a major cause of human respiratory tract disease Human bocavirus: prevalence and clinical spectrum at a children's hospital Human coronavirus NL63, a new respiratory virus Severe pneumonia and human bocavirus in adult Human bocavirus: passenger or pathogen in acute respiratory tract infections?
cord-048199-5yhe786eA once and future risk?
cord-048199-5yhe786eRisks and complications of blood transfusion Transfusion risks Risks of transfusion on behalf of the current TTI Study: Prospective investigation of transfusion transmitted infection in recipients of over 20000 units of blood Transfusion- associated immunomodulation and universal white cell reduction: are we putting the cart before the horse?
cord-048199-5yhe786eseptic sheep Limitations of blood conservation Does transfusion practice affect mortality in critically ill patients?
cord-257361-7q0vbvvdOn day 1, while assessing the site to plan patient flow, a newly recruited doctor approached and asked,"where do we get PPE?
cord-257361-7q0vbvvdhow does the centre work?
cord-048448-kfwbqp4pThe appearance of H3 influenza viruses in seals Are seals frequently infected with avian influenza viruses?
cord-048448-kfwbqp4pa mechanism for the unusual severity of human disease?
cord-282571-ilf73g71Di Yi Jun Yi Da Xue Xue Bao Neutralization of SARS- CoV-2 spike pseudotyped virus by recombinant ACE2-Ig Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus- specific human monoclonal antibody A hexapeptide of the receptor- binding domain of SARS corona virus spike protein blocks viral entry into host cells via the human receptor ACE2 Effect of angiotensin- converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin- converting enzyme 2 Angiotensin receptor blockers as tentative SARS- CoV-2 therapeutics Angiotensin II receptor blocker as a novel therapy in acute lung injury induced by avian influenza A H5N1 virus infection in mouse Population- based study of statins, angiotensin II receptor blockers, and angiotensin- converting enzyme inhibitors on pneumonia- related outcomes Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-276904-lmqschxyCOVID-19 pneumonia: ARDS or not?
cord-276856-88d3vzbsHow much can they differ before we are no longer saving two lives but risking both?
cord-276856-88d3vzbsThe central question remains: What does it mean to match patients?
cord-004096-obrq7q57Does high- dose buprenorphine cause respiratory depression?: possible mechanisms and therapeutic consequences
cord-004096-obrq7q57Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome Reply: Response to « Minimally conscious state or cortically mediated state?
cord-004096-obrq7q57what next?
cord-048343-nzk8m912Fast three dimensional sodium imaging MR imaging of sodium in the human brain with a fast three- dimensional gradient- recalled- echo sequence at 4 T Noninvasive quantification of total sodium concentrations in acute reperfused myocardial infarction using 23Na MRI Three- dimensional triplequantum- filtered( 23)Na imaging of in vivo human brain Direct, longitudinal comparison of( 1)H and( 23)Na MRI after transient focal cerebral ischemia Sodium MRI of reversible focal brain inchemia in the monkey Comprehensive MR imaging protocol for stroke management: tissue sodium concentration as a measure of tissue viability in nonhuman primate studies and in clinical studies Direct, longitudinal comparison of( 1)H and( 23)Na MRI after transient focal cerebral ischemia Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult Haloperidol prophylaxis for elderly hip- surgery patients at risk for delirium: a randomized placebo- controlled study Haloperidol use in mechanically ventilated patients is associated with lower hospital mortality Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients A randomized, double- blind, placebo- controlled trial of donepezil hydrochloride( Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement Dexmedetomidine: Can it reduce the incidence of ICU delirium in postcardiotomy patients?
cord-048343-nzk8m912Is dopamine administration possibly a risk factor for delirium?
cord-048343-nzk8m912acidic protein Is there an association between release of protein S100B during cardiopulmonary bypass and memory disturbances?
cord-005495-0mi0n2zn: it is time to consider the four D's and the four phases of fluid therapy ICU management of the patient with intraabdominal hypertension: what to do, when and to whom?
cord-005495-0mi0n2znThe duration of intra- abdominal hypertension strongly predicts outcomes for the critically ill surgical patients: a prospective observational study Intra- abdominal hypertension and abdominal compartment syndrome Intra- abdominal hypertension and acute renal failure in critically ill patients Renal implications of increased intra- abdominal pressure: are the kidneys the canary for abdominal hypertension?
cord-291955-mlju5f9uShould we deny ICU admission to the elderly?
cord-275154-vwnpred5in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?
cord-275154-vwnpred5lessons from the virus for successful vaccine design Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge Critical role of IL-17RA in immunopathology of influenza infection Confronting an influenza pandemic with inexpensive generic agents: can it be done?
cord-303577-2gxo5mftCOVID-19 and its implications for thrombosis and anticoagulation Acute pulmonary embolism and COVID-19 pneumonia: a random association?
cord-262489-cecg3gegCOVID-19 pneumonia: ARDS or not?
cord-310776-4iqu18giExploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation Is a"Cytokine Storm"relevant to COVID-19?
cord-304070-jw1lxwydWhat next for electronic communication and health care?
cord-263568-ea3k2i69Could low gastric acidity increase the risk of a severe COVID-19 illness?
cord-263568-ea3k2i69Could the severity of COVID-19 be increased by low gastric acidity?
cord-263568-ea3k2i69nan Could the severity of COVID-19 be increased by low gastric acidity?
cord-003832-q1422ydiAcute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition Etiologies, diagnostic work- up and outcomes of acute respiratory distress syndrome with no common risk factor: a prospective multicenter study Rare respiratory diseases in the ICU: when to suspect them and specific approaches Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features research statement: interstitial pneumonia with autoimmune features Interstitial pneumonia with autoimmune features: an additional risk factor for ARDS?
cord-003832-q1422ydiAnn Intensive Care Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients?
cord-003832-q1422ydiNew insights on a complex relationship Coagulation, fibrinolysis, and fibrin deposition in acute lung injury Tissue factor expression and fibrin deposition in the lungs of patients with idiopathic pulmonary fibrosis and systemic sclerosis Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?
cord-281191-n9gerpwyThe value of the autopsy in three medical eras Lung pathology of fatal severe acute respiratory syndrome Iruretagoyena JR: Autopsy as quality assurance in the intensive care unit Do autopsies of critically ill patients reveal important findings that were clinically undetected?
cord-281191-n9gerpwytitle: Autopsy in critical illness: is it obsolete?
cord-310561-67kp743fCOVID-19: room for treating T cell exhaustion?
cord-292335-al6v3b9xThe problem with cephalosporins Does antibiotic exposure increase the risk of methicillin- resistant Staphylococcus aureus( MRSA) isolation?
cord-003995-53115c1c: a retrospective observational study Is antibiotic cycling the answer to preventing the emergence of bacterial resistance in the intensive care unit?
cord-003995-53115c1cA before- and- after study of the effectiveness of an antimicrobial stewardship program in critical care Antimicrobial stewardship and intensive care unit mortality: a systematic review Antibiotic stewardship in the intensive care unit Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?
cord-003995-53115c1cincidence, risk factors, and outcome Stenotrophomonas maltophilia in the respiratory tract of medical intensive care unit patients Which patient is a candidate for empirical therapy against Stenotrophomonas maltophilia bacteraemia?
cord-326874-rdwvsm4sLearn more biomedcentral.com/submissions Ready to submit your research Ready to submit your research?
cord-003532-lcgeingzCan myocardial perfusion imaging with echo contrast help recognise type 1 acute myocardial infarction in the critically ill?
cord-003532-lcgeingzIs esmolol associated with worse outcome at the acute phase of ischemic stroke that receives thrombolysis?
cord-003532-lcgeingzThe question was"in situations where an expert opinion on an ultrasound is not immediately available, is it acceptable to get an expert review via an online medium such as WhatsApp, and would you be happy to be that expert?
cord-003532-lcgeingzWhat is the role of the pulmonary embolism severity index( PESI) and RV/ LV ratio as clinical risk assessment tools for patients undergoing ultrasound- assisted catheter- directed thrombolysis( UACDT)?
cord-323327-08p122lwBacterial pathogens and death during the 1918 influenza pandemic Is SARS just ARDS?
cord-029991-0sy417j0Author details Airway epithelial differentiation and mucociliary clearance Effect of cuffed endotracheal tubes on tracheal mucous velocity Ventilator- associated pneumonia or endotracheal tube- associated pneumonia?
cord-029991-0sy417j0What is the best pulmonary physiotherapy method in ICU?
cord-004427-dy9v9asgA diuretic protocol increases volume removal and reduces readmissions among hospitalized patients with acute decompensated heart failure Protocol- guided diuretic management: comparison of furosemide by continuous infusion and intermittent bolus Frusemide administration in critically ill patients by continuous compared to bolus therapy Comparison of two fluidmanagement strategies in acute lung injury Insidious harm of medication diluents as a contributor to cumulative volume and hyperchloremia: a prospective, open- label, sequential period pilot study ICU admission source as a predictor of mortality for patients with sepsis Does obesity protect against death in sepsis?
cord-004427-dy9v9asgEstimation of fluid status changes in critically ill patients: fluid balance chart or electronic bed weight?
cord-004427-dy9v9asgShould we really rely on it?
cord-004427-dy9v9asgTime for fluid stewardship Fluid- management strategies in acute lung injury-- liberal, conservative, or both?
cord-031033-v4yetn4fHow can we define"optimal microbiota?": a comparative review of structure and functions of microbiota of animals, fish, and plants in agriculture Host- microbiota interactions in immunemediated diseases Genomic approaches to studying the human microbiota Defining dysbiosis and its influence on host immunity and disease
cord-031033-v4yetn4fHow did these bacteria get there?
cord-031033-v4yetn4fHow to study the lung microbiome?
cord-031033-v4yetn4fSo, the more appropriate question is'do patients that develop pneumonia have more dysbiosis of the lung microbiome than mechanically ventilated ICU patients who do not develop pneumonia'?
cord-031033-v4yetn4fWhat is the healthy gut microbiota composition?
cord-293167-3bd3adipAssociated with SARS- CoV-2 Guillain- Barré syndrome associated with SARS- CoV-2 infection: causality or coincidence?
cord-293167-3bd3adipGuillain- Barré syndrome following COVID-19: new infection, old complication?
cord-265022-p5cab562Vascular aspects of cognitive impairment and dementia Can angiotensin- converting enzyme inhibitors impact cognitive decline in early stages of Alzheimer's disease?
cord-265022-p5cab562yes or no?
cord-010697-0eutz8xy: does the system matter?
cord-010697-0eutz8xyExtracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta- analysis ECMO as a bridge to decision: recovery, VAD, or heart transplantation?
cord-010697-0eutz8xyMRI Hypoxia- induced inflammation in the lung: a potential therapeutic target in acute lung injury?
cord-010697-0eutz8xyWeaning failure in the operating room: have you considered Preweaning bronchoscopy?
cord-010697-0eutz8xyhow safe is it?
cord-000891-5r2in1gw: can we predict it?
cord-000891-5r2in1gwDoes this patient have influenza?
cord-000891-5r2in1gwEmilio title: Should lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season?
cord-000891-5r2in1gwShould lower respiratory tract secretions from intensive care patients be systematically screened for influenza virus during the influenza season?
cord-000891-5r2in1gwWhen should a diagnosis of influenza be considered in adults requiring intensive care unit admission?
cord-329381-uwae8738COVID-19 pneumonia: ARDS or not?
cord-327622-ezgufe24Cases, data and surveillance Exhaled air dispersion and removal is influenced by isolation room size and ventilation settings during oxygen delivery via nasal cannula Airflow and droplet spreading around oxygen masks: a simulation model for infection control research Airflows around oxygen masks: a potential source of infection?
cord-327622-ezgufe24anesthetic concerns, including airway management and infection control High- flow nasal cannula therapy as apneic oxygenation during endotracheal intubation in critically ill patients in the intensive care unit: a systematic review and metaanalysis Mask ventilation and dispersion of exhaled air Effect of ventilator circuit changes on ventilator- associated pneumonia: a systematic review and meta- analysis Trends in tracheostomy for mechanically ventilated patients in the United States Tracheotomy in ventilated patients with COVID-19 CORONA- steps for tracheotomy in COVID-19 patients: a staff- safe method for airway management Negativepressure aerosol cover for COVID-19 tracheostomy Does endotracheal tube clamping prevent air leaks and maintain positive endexpiratory pressure during the switching of a ventilator in a patient in an intensive care unit?
cord-290392-kpjp0sx4Can we consider all the cases of acute respiratory failure associated with COVID-19 as ARDS?
cord-290392-kpjp0sx4cord-290392-kpjp0sx4 authors: Li, Xu; Ma, Xiaochun title: Acute respiratory failure in COVID-19: is it “ typical ” ARDS?
cord-314310-g1zmggf4: TPE seems to be a treatment that may improve outcomes by effectively removing fibrin degradation products and restoring coagulation status: fact or fiction?
cord-314310-g1zmggf4Finally, given the variety of additional treatments( e.g., antiviral drugs, cytokine filters, steroids) that the patients in the study received, how can one be certain of which treatment(s) ultimately influenced mortality?
cord-314310-g1zmggf4nan TPE seems to be a treatment that may improve outcomes by effectively removing fibrin degradation products and restoring coagulation status: fact or fiction?
cord-351264-zp41u14lClinical course and outcomes of 344 intensive care patients with COVID-19 COVID-19 pneumonia: different respiratory treatments for different phenotypes?
cord-326315-ncfxlnpjHow deadly is seasonal influenza associated pneumonia?
cord-343940-fdnmeuh8For study reference see Table 1 Characteristics of and important lessons from the coronavirus disease 2019( COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention Mechanical ventilation in COVID-19: interpreting the current epidemiology Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Acute respiratory distress syndrome: the Berlin Definition COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?
cord-260215-gsnjlhjdAre outcomes the same with all dry powder inhalers?
cord-260215-gsnjlhjdInhaled antibiotics: dry or wet?
cord-260215-gsnjlhjdInhaled bronchodilator administration during mechanical ventilation: how to optimize it, and for which clinical benefit?
cord-260215-gsnjlhjdIs inhalation rate important for a dry powder inhaler?
cord-353344-tzyu6j6ntitle: Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?
cord-315685-ute3dxwuCOVID-19 cases Is there an ideal animal model for SARS?
cord-315685-ute3dxwuSARS- CoV-2 receptor ACE2 is an interferon- stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues Asymptomatic and human- to- human transmission of SARS- CoV-2 in a 2-family cluster Transmission of 2019-nCoV infection from an asymptomatic contact in Germany Histopathology and ultrastructural findings of fatal COVID-19 infections Autopsy findings and venous thromboembolism in patients with COVID-19 Offline: a global health crisis?
cord-338990-vrtzyo2oI have no plan for this Part of the cure or am I part of the disease?
cord-338990-vrtzyo2oIs it ethical to ask intensivists and other healthcare providers to counter this contagious threat with inadequate battle gear?
cord-338990-vrtzyo2oWhat level of interaction after a day at work is safe between healthcare providers caring for COVID-19 patients and their families?
cord-293690-pxiv0m7nIn conclusion, what could we learn from the Italian COVID-19 outbreak?
cord-293690-pxiv0m7nWhere should have been earlier and properly noninvasively supported acute patients with and without COVID-19 to keep the highest the ICU capacity?
cord-334391-0172afa1Choose BMC and benefit from:?
cord-334391-0172afa1Kolkata, India Ready to submit your research Ready to submit your research?
cord-352227-827987jf: highdimensional undirected graph estimation Microbiome responses to an uncontrolled short- term diet intervention in the frame of the Citizen Science Project Rural and urban microbiota: to be or not to be?
cord-352227-827987jfOscillospira: a central, enigmatic component of the human gut microbiota Akkermansia muciniphila in the human gastrointestinal tract: when, where, and how?
cord-352227-827987jfRegional homovanillic acid production in humans Catabolism of 3-and 4-hydroxyphenylacetic acid by Klebsiella pneumonia Catabolism of aromatic biogenic amines by Pseudomonas aeruginosa PAO1 via meta cleavage of homoprotocatechuic acid Intraalveolar catecholamines and the human lung microbiome Pseudomonas aeruginosa- catecholamine inotrope interactions: a contributory factor in the development of ventilator- associated pneumonia?
cord-270298-zv0t3d0mIn answer to the question'What can we do?'
cord-270298-zv0t3d0mRecently published papers: pulmonary care, pandemics, and eugenics in surviving sepsis?
cord-270298-zv0t3d0mdoes it mean?
cord-270298-zv0t3d0mventilator associated and healthcare- associated pneumonia Impact of humidification systems on ventilator associated pneumonia Contribution of blinded, protected quantitative specimens to the diagnostic and therapeutic management of ventilator associated pneumonia Noninvasive vs conventional mechanical ventilation in acute respiratory failure: a multicenter, randomised controlled trial Non- invasive ventilation for acute respiratory failure: but how severe?
cord-347833-b3yrxkt0The third international consensus definitions for sepsis and septic shock( sepsis-3) Does infection- induced immune activation contribute to dementia?
cord-347833-b3yrxkt0What do we know about quality of life in dementia?
cord-004327-ofqay81v-technical aspects How early should VATS be performed for retained haemothorax in blunt chest trauma?
cord-004327-ofqay81v: what is the benefit?
cord-004327-ofqay81vChest wall trauma Management of flail chest injury: internal fixation versus endotracheal intubation and ventilation Surgical stabilization of internal pneumatic stabilization?
cord-004327-ofqay81vLessons from a large trauma center: impact of blunt chest trauma in polytrauma patients- still a relevant problem?
cord-004327-ofqay81va prospective, observational, multicenter AAST study Effectiveness of surgical rib fixation on prolonged mechanical ventilation in patients with traumatic rib fractures: a propensity score- matched analysis Chest wall stabilization in ventilator- dependent traumatic flail chest patients: who benefits?
cord-004327-ofqay81vwhy, when, and how?
cord-307512-70j4vn78CCPR, compression only CPR; PPE, personal protective equipment; TTM, targeted temperature management; WLST, withdrawal of life- sustaining therapy survivors with ECPR during the COIVD-19 pandemic, but at what individual and health opportunity cost?
cord-307512-70j4vn78Ir Protecting health- care workers from subclinical coronavirus infection Tackling covid-19: are the costs worth the benefits?
cord-307512-70j4vn78Should we emergently revascularize occluded coronaries for cardiac arrest?
cord-345973-fb3gkc0f-case series Baseline characteristics and outcomes of 1591 patients infected with SARS- CoV-2 admitted to ICUs of the Lombardy region Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-345973-fb3gkc0f: Society of Critical Care Medicine( SCCM) and American Society for Parenteral and Enteral Nutrition Should immunonutrition become routine in the critically ill patient?
cord-345973-fb3gkc0fA Multicenter Cohort Study First case of 2019 novel coronavirus in the United States Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus- infected pneumonia in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Evidence for gastrointestinal infection of SARS- CoV-2 Gastrointestinal manifestations of SARS- CoV-2 infection and virus load in fecal samples from the Hong Kong cohort and systematic review and meta- analysis Enteric involvement of coronaviruses: is faecal- oral transmission of SARS- CoV-2 possible?
cord-297062-dmiplvt2: how close are we?
cord-297062-dmiplvt2Epidemiological update: Middle East respiratory syndrome coronavirus?
cord-297062-dmiplvt2Middle East respiratory syndrome coronavirus outbreak in the Republic of Korea Middle East respiratory syndrome coronavirus( MERS- CoV): what lessons can we learn?
cord-034948-w59wxu8iAre they useful?
cord-034948-w59wxu8iIs the leak test reproducible?
cord-034948-w59wxu8iLaryngeal ultrasound versus cuff leak test in prediction of post- extubation stridor Cuff leak test for the diagnosis of post- extubation stridor Laryngeal ultrasonography versus cuff leak test in predicting postextubation stridor Clinical risk, cuff leak test and laryngeal ultrasound based scoring system to predict postextubation stridor in intensive care unit patients Determinants of the cuff- leak test: a physiological study The cuff- leak test: what are we measuring?
cord-034948-w59wxu8iThe cuff leak test: does it"leak"any information?
cord-034948-w59wxu8iThe cuff- leak test as a predictor of postextubation stridor: a prospective study Evaluation of the cuff- leak test in a cardiac surgery population Measurement of endotracheal tube cuff leak to predict postextubation stridor and need for reintubation How to identify patients with no risk for postextubation stridor?
cord-034948-w59wxu8ia case series Laryngeal air column width ratio in predicting post extubation stridor How often do systematic reviews exclude articles not published in English?
cord-000522-d498qj2bCan drotrecogin alfa( activated) be used in patients on dialysis for pre- existing renal failure, a category that was specifically excluded in the PROWESS trial?
cord-000522-d498qj2bDo patients require any laboratory testing before they receive drotrecogin alfa( activated)?
cord-000522-d498qj2bHow do severe sepsis and septic shock differ hemodynamically in the early stages compared with that classically described in the ICU?
cord-000522-d498qj2bWhat are the most important ways in which EGDT can improve outcomes?
cord-000522-d498qj2bWhat is the optimal dose for this intervention?
cord-000522-d498qj2bWhat is the optimal duration for this intervention?
cord-000522-d498qj2bWhy was cardiovascular collapse a significant cause of death in the control group?
cord-104180-f3hoz9buCan we manipulate this therapeutically in human sepsis?
cord-104180-f3hoz9buRecently published papers: inflammation, elucidation, manipulation?
cord-104180-f3hoz9buSo will stress doses of hydrocortisone attenuate severe systemic inflammatory response syndrome after cardiac surgery with cardiopulmonary bypass?
cord-104180-f3hoz9buWhy is this so?
cord-104180-f3hoz9buWith respect to inotropes, which one should we use?
cord-104180-f3hoz9bua prospective clinical trial Adrenocortical hormones in survivors and nonsurvivors of severe sepsis: diverse time course of dehydroepiandrosterone, dehydroepiandrosterone- sulfate, and cortisol Stress doses of hydrocortisone reduce severe systemic inflammatory response syndrome and improve early outcome in a risk group of patients after cardiac surgery Coagulation blockade prevents sepsis- induced respiratory and renal failure in baboons Blockade of tissue factor: treatment for organ injury in established sepsis Development of ionized hypomagnesemia is associated with higher mortality rates Injurious mechanical ventilation and end- organ epithelial cell apoptosis and organ dysfunction in an experi- Critical Care Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: a randomized controlled trial Prevention of endotracheal suctioning- induced alveolar derecruitment in acute lung injury Dose- response characteristics during long- term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized, controlled study Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: Which is best?
cord-014464-m5n250r210 Questions to Help You Make Sense of Qualitative Research Quality measurement at intensive care units: which indicators should we use?
cord-014464-m5n250r2An Acute Problem?
cord-014464-m5n250r2As TEG measures the thrombodynamic properties of whole blood coagulation, perhaps it is a more reliable indicator of heparin activity?
cord-014464-m5n250r2Both hypoxemia and extreme hyperoxemia may be detrimental in patients with severe traumatic brain injury Focused assessment with sonography in trauma( FAST): should its role be reconsidered?
cord-014464-m5n250r2Early prognosis in traumatic brain injury: from prophecies to predictions One- year extended Glasgow Outcome Scale and hospital mortality predictors in patients with severe traumatic brain injury in Brazil R Turon 1, FR Ferreira 1, D Prado 1 Bioavailability of subcutaneous low- molecular- weight heparin to patients on vasopressors Prophylactic anticoagulation with enoxaparin: is the subcoutaneous route appropriate in the critically ill?
cord-014464-m5n250r2Introduction Are safety guidelines being followed when administering procedural sedation in the emergency department?
cord-014464-m5n250r2Overcrowding estimation in the emergency department: is the simplest score the best?
cord-335172-5ig907onFinally, and more controversially, should we evaluate the modulating effects of AngII on ACE2 for the treatment of COVID-19 in patients without shock?
cord-335172-5ig907onFor instance, should AngII be used for all COVID-19 patients in shock?
cord-335172-5ig907onShould it be considered earlier in the course of disease, perhaps as a first- line vasopressor?
cord-335172-5ig907onkey: cord-335172- 5ig907on authors: Busse, Laurence W.; Chow, Jonathan H.; McCurdy, Michael T.; Khanna, Ashish K. title: COVID-19 and the RAAS — a potential role for angiotensin II?
cord-319101-2vdd10mu: when is it unjustified?
cord-319101-2vdd10muCOVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?
cord-319101-2vdd10muIn this context, can ECMO be justified in the epicenter of a pandemic?
cord-319101-2vdd10muThe role of ECMO in COVID-19: can it provide rescue therapy in those who are critically ill?
cord-319101-2vdd10mufrom salvage to standard of care?
cord-003513-hmdikgf5Diagnosis: Is it possible to predict gram- negative MDR pathogens in CAP?
cord-003513-hmdikgf5Prevalence: What is the prevalence?
cord-003513-hmdikgf5Prevalence: What is the prevalence?
cord-003513-hmdikgf5The pathogen: How important is A. baumanii in CAP?
cord-003513-hmdikgf5The pathogen: What is so special about K. pneumoniae in CAP?
cord-003513-hmdikgf5The pathogen: What is so special about S. maltophilia in CAP?
cord-003513-hmdikgf5The pathogen: Why is it difficult to treat?
cord-003513-hmdikgf5Therapy: How is it possible to treat these pathogens?
cord-003513-hmdikgf5a European perspective Microbial aetiology of communityacquired pneumonia and its relation to severity Multidrug- resistant, extensively drug- resistant and pandrug- resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internetbased global point prevalence survey European Antimicrobial Resistance Surveillance Network Pseudomonas aeruginosa: new insights into pathogenesis and host defenses Which microbial factors really are important in Pseudomonas aeruginosa infections?
cord-003513-hmdikgf5case report and review of the literature Community- acquired pneumonia infections by Acinetobacter baumannii: how does alcohol impact the antimicrobial functions of macrophages?
cord-005497-w81ysjf9( 1) Are serum- S1P levels affected by cardiac surgery?
cord-005497-w81ysjf9( 2) Are potential alterations of serum- S1P levels related to changes of acute- phase proteins, S1P sources or carrier?
cord-005497-w81ysjf9( 3) Is the invasiveness of the surgery a factor that may influence serum- S1P levels?
cord-005497-w81ysjf9A hybrid approach as treatment for coronary artery disease: endo- CABG or PCI first, does it matter?
cord-005497-w81ysjf9Assessing the volume of blood taken for blood culture and culture positivitydo we need to take less blood?
cord-005497-w81ysjf9Does the endotoxin adsorption of PMX column saturate in 2 hours?
cord-005497-w81ysjf9What is the useful coagulation and fibrinolysis marker for predicting extracorporeal membrane oxygenation circuit exchange due to intra- circuit thrombus?
cord-286771-77hs34jmAcute respiratory failure following pharmacologically induced hyperventilation: an experimental animal study Mechanisms of atelectasis in the peri- operative period Reabsorption atelectasis in a porcine model of ARDS: regional and temporal effects of airway closure, oxygen, and distending pressure Lung stress and strain during mechanical ventilation: any difference between statics and dynamics?
cord-286771-77hs34jmCOVID-19 pneumonia: ARDS or not?
cord-286771-77hs34jmCan high- flow nasal cannula reduce the rate of endotracheal intubation in adult patients with acute respiratory failure compared with conventional oxygen therapy and noninvasive positive pressure ventilation?
cord-286771-77hs34jmGiven the fact that regional strain and heterogeneity are present during a normal respiratory cycle without harming the lung leads to the question: why P- SILI does not develop in normal lungs deformed by physiologic Vt?
cord-286771-77hs34jmSevere Covid-19 disease: rather AVDS than ARDS?
cord-286771-77hs34jmThe link between regional tidal stretch and lung injury during mechanical ventilation Deterioration of regional lung strain and inflammation during early lung injury Mechanotransduction in the lungs Towards prevention of ventilatorinduced lung injury: is mechanotransduction the answer?
cord-286771-77hs34jmThe role of three- dimensionality and alveolar pressure in the distribution and amplification of alveolar stresses Does regional lung strain correlate with regional inflammation in acute respiratory distress syndrome during nonprotective ventilation?
cord-286771-77hs34jmVentilation- induced lung injury exists in spontaneously breathing patients with acute respiratory failure: yes Spontaneous breathing in early acute respiratory distress syndrome: insights from the large observational study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study Balancing forces: architectural control of mechanotransduction Lung stress and strain during mechanical ventilation: any safe threshold?
cord-286771-77hs34jmWhen to promote spontaneous respiratory activity in acute respiratory distress patients?
cord-286771-77hs34jma multicenter cohort study Clinical practice and risk factors for immediate complications of endotracheal intubation in the intensive care unit: a prospective, multiple- center study COVID-19 pneumonia: different respiratory treatments for different phenotypes?
cord-341063-3rqnu5bu-If not currently using has it been considered?
cord-341063-3rqnu5bu-Which antibiotics are you using for continuous or extended infusions?
cord-341063-3rqnu5buIs enzymatic debridement better in critically burned patients?
cord-341063-3rqnu5buP441 Acquired neuromuscular weakness in eldery patients with femoral bone fracture, could we decrease the incidence?
cord-341063-3rqnu5buQuestions included:-Are you using continuous or extended antibiotic infusions?
cord-341063-3rqnu5buUsing a protocol for fluid resuscitation: how well is it followed?
cord-341063-3rqnu5buWhat are physicians in doubt about?
cord-341063-3rqnu5buis it still required?