trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
the presence of	216
respiratory syndrome coronavirus	168
severe acute respiratory	156
in the presence	156
the cells were	156
acute respiratory syndrome	154
herpes simplex virus	147
as well as	131
in this study	124
antiviral activity of	122
east respiratory syndrome	117
middle east respiratory	117
the treatment of	117
shown in fig	105
as shown in	103
respiratory syncytial virus	103
the effect of	103
were infected with	99
in vitro and	98
the development of	94
been shown to	89
hepatitis c virus	87
for the treatment	87
for h at	87
and in vivo	86
mg kg day	85
cov pl pro	83
were treated with	82
the antiviral activity	81
cd t cells	79
the absence of	78
a number of	78
of the viral	78
in the absence	76
vitro and in	75
of the virus	74
cells were infected	71
a and b	71
antiviral res doi	70
was added to	69
based on the	65
to determine the	65
data not shown	65
has been shown	64
the replication of	63
was used to	63
the number of	61
influenza virus infection	61
hp and hp	61
the expression of	60
influenza a virus	58
human immunodeficiency virus	58
mechanism of action	58
it has been	58
found to be	57
the inhibition of	57
according to the	56
to evaluate the	54
one of the	54
due to the	54
cells were treated	53
in order to	53
of severe acute	53
shown to be	53
structure of the	52
in the lungs	52
for treatment of	52
virus infection in	51
hepatitis b virus	50
pedv pl pro	50
simplex virus type	50
used as a	50
as described previously	49
the present study	49
in the case	48
to be a	48
in cell culture	48
the case of	47
c for h	47
balb c mice	47
the efficacy of	47
added to the	47
a variety of	46
was found to	46
type i fcov	45
the role of	45
cells were incubated	45
infectious bronchitis virus	45
the effects of	45
of middle east	45
antiviral activity against	45
compared to the	45
were used to	45
the levels of	44
was used as	44
of influenza virus	44
the use of	44
cells were seeded	43
virus replication in	43
activity of the	43
were incubated with	43
in the present	42
the level of	42
the n protein	42
analysis of the	42
of rnase l	42
inhibitory effect on	41
were transfected with	41
vero cells were	41
a concentration of	41
showed that the	41
results showed that	40
cells infected with	40
of action of	40
cells in the	40
at room temperature	40
of herpes simplex	40
li et al	39
by plaque assay	39
of ebola virus	39
of influenza a	38
the amount of	38
chen et al	38
with or without	37
that of the	37
at a concentration	37
be used to	37
ea and la	37
the in vitro	37
pd and rw	37
we found that	37
hepatitis a virus	37
the ebn extract	36
pl pro s	36
in the viral	36
have shown that	36
the results of	36
was shown to	36
to that of	36
has been reported	36
vero e cells	36
results suggest that	36
in vero cells	35
on the other	35
the control group	35
of the sars	35
were seeded in	35
the lack of	35
feline infectious peritonitis	35
the activation of	34
cells were transfected	34
were added to	34
the mechanism of	34
and respiratory syndrome	34
and incubated at	34
involved in the	34
antiviral effect of	34
the other hand	34
the activity of	33
were determined by	33
such as the	33
as previously described	33
in a dose	33
of the n	33
in contrast to	33
a series of	33
were cultured in	33
cells treated with	33
c bl j	32
the surface of	32
crystal structure of	32
to inhibit the	32
used for the	32
t cells were	32
results indicate that	32
was supported by	32
and rw peptides	32
for min at	32
of the two	32
as described in	32
cells were washed	32
the formation of	32
fetal bovine serum	32
has been used	32
as compared to	31
the s protein	31
porcine reproductive and	31
was determined by	31
the host cell	31
a h n	31
lower respiratory tract	31
reproductive and respiratory	31
the antiviral effect	31
inhibitory effect of	31
suggesting that the	31
liu et al	31
was carried out	31
were purchased from	30
as described above	30
lee et al	30
in patients with	30
of sukumo extract	30
is required for	30
dependent rna polymerase	30
the end of	30
by western blotting	30
zhang et al	30
been reported to	30
inhibitory effects of	30
was removed and	30
to the cells	29
increasing concentrations of	29
in which the	29
lung slice model	29
effect of the	29
the induction of	29
p and jnk	29
than that of	29
in dromedary camels	29
in combination with	29
cov n protein	29
observed in the	29
the inhibitory effect	29
in vitro antiviral	29
transmissible gastroenteritis virus	29
the addition of	28
the concentration of	28
lin et al	28
replication in the	28
were found to	28
respiratory syndrome virus	28
could be used	28
were grown in	28
for the development	28
role in the	28
cells were then	28
can be used	28
and treated with	27
at h post	27
incubated for h	27
were used as	27
infected cells were	27
the respiratory tract	27
cells were fixed	27
c for min	27
in the treatment	27
able to inhibit	27
an important role	27
b and c	27
antiviral and anti	27
binding to the	26
end of the	26
suggest that the	26
three independent experiments	26
cytokines and chemokines	26
the inhibitory effects	26
region of the	26
have been shown	26
there is a	26
h n virus	26
the spike protein	26
of vaccinia virus	26
similar to that	26
the ability of	25
plaque reduction assay	25
of m f	25
of viral replication	25
the control of	25
the synthesis of	25
the cell surface	25
the crystal structure	25
mode of action	25
important role in	25
as a result	25
h after infection	24
n a l	24
type i ifn	24
of p and	24
the discovery of	24
african horse sickness	24
used in the	24
a l p	24
u r n	24
this work was	24
sukumo extract was	24
the viral membrane	24
and incubated for	24
in the control	24
p r o	24
the viral envelope	24
of hepatitis c	24
j o u	24
o o f	24
the importance of	24
o u r	24
cd and cd	24
type i interferon	24
l p r	24
of these compounds	24
influenza a h	24
r o o	24
added to each	24
p r e	24
r n a	24
expression of the	24
infection in vitro	24
inhibition of viral	24
of respiratory syncytial	23
influenza a and	23
data suggest that	23
effect on the	23
influenza a viruses	23
characterization of the	23
detected in the	23
each of the	23
replication in vitro	23
h post infection	23
was measured by	23
well as the	23
in addition to	23
of the cells	23
the lungs of	23
the binding of	23
activation of the	23
used in this	23
the university of	23
were incubated at	23
effects of the	23
three times with	23
cells were collected	22
the detection of	22
of antiviral drugs	22
these results indicate	22
was incubated with	22
west nile virus	22
svv c pro	22
in cell cultures	22
were analyzed by	22
determined by plaque	22
chang et al	22
we have previously	22
hek t cells	22
mice infected with	22
wang et al	22
the active site	22
were obtained from	22
was observed in	22
of u a	22
and in the	22
respiratory tract infections	22
inhibitory effects on	22
the current study	22
or absence of	22
in response to	22
of viral rna	22
a novel coronavirus	22
the viral genome	22
c and d	22
was used for	21
the percentage of	21
at h p	21
porcine epidemic diarrhea	21
in the brain	21
is essential for	21
a combination of	21
are involved in	21
wu et al	21
have been identified	21
data indicate that	21
were used for	21
the results showed	21
of viral infection	21
and hp peptides	21
been used to	21
of the s	21
immunodeficiency virus type	21
at an moi	21
the severe acute	21
infectious peritonitis virus	21
did not show	21
virus replication by	21
of q r	21
multiplicity of infection	21
chou et al	21
is able to	21
cov spike protein	21
a result of	21
in infected cells	21
against herpes simplex	21
concentration of the	21
final concentration of	21
member of the	21
can be found	21
an moi of	21
the polymerase reaction	21
was able to	21
were carried out	20
chronic hepatitis b	20
inhibitory activity against	20
against influenza virus	20
of a novel	20
bind to the	20
presence or absence	20
activity of a	20
h n influenza	20
for use in	20
indicating that the	20
work was supported	20
have been used	20
had no effect	20
the infectivity of	20
because of the	20
various concentrations of	20
g ml and	20
indicate that the	20
of type i	20
have been reported	20
of transmissible gastroenteritis	20
assay was performed	20
demonstrated that the	20
and stored at	20
of the coronavirus	20
was purchased from	20
some of the	20
suggests that the	20
infected vero cells	20
the inhibitory activity	20
infection in the	20
presence of the	20
of pedv pl	20
pi k akt	20
is associated with	20
cells per well	20
to determine whether	20
western blot analysis	20
of the protein	20
coronavirus nucleocapsid protein	20
described in section	20
the sukumo extract	20
epidemic diarrhea virus	19
infected with hsv	19
of influenza viruses	19
as a negative	19
no effect on	19
to each well	19
of the compound	19
ren et al	19
mouse lung slice	19
in clinical trials	19
shown to have	19
world health organization	19
in the laiv	19
led to the	19
on the surface	19
virus titers in	19
these results suggest	19
the influenza virus	19
in saudi arabia	19
replication of the	19
transmissible gastroenteritis coronavirus	19
compared with the	19
the structure of	19
p and p	19
inhibitors of the	19
the combination of	19
in the cytoplasm	19
mohan et al	19
was detected in	19
mouse lung slices	19
at c for	19
of the ebn	19
cells were cultured	19
is the first	19
most of the	19
the production of	19
similar to the	19
upper respiratory tract	19
mouse hepatitis virus	19
be used as	18
against influenza a	18
and analyzed by	18
the interaction of	18
for min and	18
in the current	18
in comparison with	18
to assess the	18
syncytial virus infection	18
and the cells	18
infection in mice	18
in the same	18
there was no	18
innate immune response	18
at the same	18
high levels of	18
was performed with	18
resulted in a	18
a role in	18
memory cd t	18
the mouse lung	18
t cells in	18
inoculum was removed	18
has also been	18
specific cd t	18
shown to inhibit	18
be used for	18
inhibitory activity of	18
there is no	18
derived from the	18
horse sickness virus	18
it is a	18
of the rna	18
the compounds were	18
their ability to	18
the fact that	18
of porcine reproductive	18
reduction in viral	18
of hp and	18
of the compounds	18
mechanisms of action	18
cov and sars	18
well plates were	18
antiviral activity was	18
viral life cycle	18
pcr was performed	18
and in vitro	18
zhao et al	18
part of the	18
syndrome coronavirus infection	18
h n and	18
morbidity and mortality	18
identification of a	18
inhibition of the	18
found in the	18
a density of	17
similar to those	17
we showed that	17
article can be	17
a negative control	17
in the pre	17
it is not	17
the in vivo	17
development of a	17
for at least	17
to investigate the	17
ebola virus infection	17
a potent inhibitor	17
the infection of	17
of sialic acid	17
vesicular stomatitis virus	17
be able to	17
mice treated with	17
in terms of	17
are shown in	17
was performed as	17
in the s	17
than in the	17
regions of the	17
was performed using	17
antiviral activity in	17
of ea and	17
type ii fcov	17
amino acid residues	17
the potential to	17
concentrations of the	17
of the influenza	17
potent inhibitor of	17
the interaction between	17
were fixed with	17
cells were grown	17
and cells were	17
were able to	17
indicated that the	17
this article can	17
cov infection in	17
min at room	17
the viral life	17
the viral rna	16
for h and	16
was evaluated by	16
a wide range	16
treatment of influenza	16
the m protein	16
zhou et al	16
is a potent	16
of this study	16
of a new	16
none of the	16
by western blot	16
the middle east	16
supported by the	16
of the cell	16
washed three times	16
a mouse model	16
the h n	16
wide range of	16
mice immunized with	16
be due to	16
viruses such as	16
of antiviral activity	16
were subjected to	16
the inoculum was	16
at least three	16
of mg kg	16
viral replication in	16
the emergence of	16
the infected cells	16
or infected with	16
found that the	16
of infected cells	16
the presence or	16
is involved in	16
cd tem cells	16
post virus exposure	16
role of the	16
there are no	16
parainfluenza virus type	16
activity in the	16
infected with the	16
of the polymerase	16
the lung slice	16
total rna was	16
virus in vitro	16
but not in	16
the type i	16
to analyze the	16
cell monolayers were	16
the sars coronavirus	16
in accordance with	16
after removal of	16
need to be	16
kulka et al	16
was detected by	16
prior to infection	16
a member of	16
with that of	16
the growth of	16
positron emission tomography	16
there was a	16
cd t rm	16
to interfere with	16
of the antiviral	16
national institute of	16
cell lysates were	15
are expressed as	15
proved to be	15
at the indicated	15
at a density	15
that in the	15
the influence of	15
central nervous system	15
assays were performed	15
the results were	15
the identification of	15
memory t cells	15
activity of luciferase	15
of g ml	15
dependent on the	15
these data suggest	15
the united states	15
different concentrations of	15
for the detection	15
the virus titer	15
changes in the	15
of the ifn	15
virus in the	15
spectrum antiviral activity	15
protein levels of	15
the antiviral effects	15
shown in table	15
egfr pi k	15
thermo fisher scientific	15
resulting in the	15
and b viruses	15
to those of	15
kindly provided by	15
the frequency of	15
performed as described	15
of the human	15
of sars coronavirus	15
this study was	15
in the mouse	15
of the target	15
were maintained in	15
in the early	15
serve as a	15
significantly reduced the	15
h at c	15
effect of arb	15
to the virus	15
titers were determined	15
the ability to	15
treatment with the	15
induced by the	15
to be the	15
the release of	15
the observation that	15
vitro antiviral activity	15
mouth disease virus	15
with pbs and	15
the phosphorylation of	15
with severe acute	15
i fcov replication	15
are able to	15
that m f	15
hela g cells	15
cell viability was	15
fold increase in	15
zika virus infection	15
of hepatitis a	15
shown that the	15
inhibition of virus	15
after treatment with	15
any of the	15
it should be	15
compared to that	15
is the most	15
a recent study	15
kim et al	15
is dependent on	15
added to cells	15
vivo and in	15
in vitro anti	15
incubated at c	15
antiviral activity and	14
the slices were	14
cheng et al	14
were shown to	14
of human immunodeficiency	14
the study of	14
an increase in	14
by the viral	14
in mdck cells	14
resulting in a	14
culture supernatants were	14
of the drugs	14
used as the	14
the mouse model	14
fixed with paraformaldehyde	14
with u a	14
the most effective	14
luc e l	14
amc dcba lozenge	14
of the first	14
lump et al	14
of hepatitis b	14
development of antiviral	14
a total of	14
it can be	14
in our laboratory	14
levels of the	14
cells transfected with	14
the supernatant was	14
that the anti	14
of the host	14
extract from s	14
by the addition	14
effect of celastrol	14
is important for	14
treated with the	14
times with pbs	14
present in the	14
in medium containing	14
was performed to	14
known to be	14
were incubated for	14
antiviral effects of	14
suggested that the	14
cells were rinsed	14
been shown that	14
with the virus	14
in the middle	14
differences in the	14
ebola virus glycoprotein	14
of mg ml	14
in children with	14
is known to	14
cells for h	14
in the culture	14
consistent with the	14
ranging from to	14
are known to	14
that myricetin may	14
medium supplemented with	14
the virus and	14
inhibit the replication	14
respiratory tract disease	14
infected with tgev	14
to the host	14
between the two	14
it is possible	14
the monolayer cells	14
in mice and	14
an inhibitor of	14
were performed in	14
to interact with	14
a reduction in	14
sun et al	14
did not affect	14
human parainfluenza virus	14
pcpur u i	14
we have shown	14
b and d	14
both antiviral and	14
of virus replication	14
avian infectious bronchitis	14
after h of	14
the incidence of	14
caused by the	14
lung slices were	14
studies have shown	14
of infectious diseases	14
for antiviral activity	14
in tissue culture	14
in the lung	14
understanding of the	14
the mtt assay	14
the evaluation of	14
was associated with	14
higher than that	14
been reported that	13
sequence of the	13
romanovskaya et al	13
the absence or	13
the virology branch	13
were washed with	13
protein of sars	13
and characterization of	13
the effective concentration	13
function of the	13
approved by the	13
it is likely	13
of dengue virus	13
evaluation of the	13
by treatment with	13
we investigated the	13
was performed in	13
its ability to	13
cultured in medium	13
has not been	13
viral and cellular	13
the experiment was	13
due to its	13
the design of	13
were detected in	13
coronaviral pl pro	13
the time of	13
ava cells were	13
of infectious bronchitis	13
medium was removed	13
of the enzyme	13
absence or presence	13
experiments were performed	13
reduction of virus	13
indicates that the	13
obtained from the	13
was isolated from	13
conjugated goat anti	13
is shown in	13
the cytotoxicity of	13
was obtained from	13
was extracted from	13
cys and his	13
the ministry of	13
brooks et al	13
h prior to	13
in immunocompromised patients	13
with a lethal	13
the virus was	13
play an important	13
were tested for	13
was determined using	13
of zika virus	13
interaction between the	13
these data indicate	13
virus infection and	13
that can be	13
at the end	13
a family of	13
the function of	13
the entry of	13
to be effective	13
of pfu ml	13
the data presented	13
a reduction of	13
h before infection	13
this is a	13
is likely that	13
avian influenza virus	13
with increasing concentrations	13
presence of increasing	13
the nucleocapsid protein	13
we evaluated the	13
c mice were	13
and can be	13
by rna interference	13
interfere with the	13
inhibit replication of	13
were collected at	13
efficacy of the	13
comparison of the	13
supernatants were harvested	13
from the virology	13
respiratory viral infections	13
or presence of	13
yang et al	13
ebn extract from	13
the impact of	13
a multiplicity of	13
rna and dna	13
well as in	13
and h after	13
h n viruses	13
the generation of	13
in the range	13
with the control	13
have demonstrated that	13
proven to be	13
to the cell	13
depending on the	13
groups of mice	13
and table s	13
and treatment of	13
with each of	13
monolayer cells were	13
plates at a	12
of vero cells	12
lethal dose of	12
and dna viruses	12
in agreement with	12
mediated by the	12
influenza virus and	12
of the spike	12
takano et al	12
and h post	12
the host cells	12
data were analyzed	12
in complex with	12
infected or infected	12
are required for	12
treated with or	12
m f and	12
activity of diabzi	12
a lethal dose	12
to the viral	12
with a high	12
the ex vivo	12
binding and entry	12
we did not	12
at the level	12
was analyzed by	12
coronavirus spike protein	12
to increase the	12
at c co	12
high level of	12
of chronic hepatitis	12
treated with increasing	12
as a novel	12
polymerase chain reaction	12
after h incubation	12
and function of	12
the effectiveness of	12
titers in the	12
piv and hrv	12
and the monolayer	12
of these viruses	12
belongs to the	12
was used in	12
by contract no	12
as a potential	12
and evaluation of	12
were applied to	12
the concentrations of	12
the relationship between	12
of rna viruses	12
associated with the	12
a dose of	12
dromedary camels in	12
mutation in the	12
is mediated by	12
academy of sciences	12
cells and incubated	12
and mg kg	12
washed with pbs	12
plays an important	12
yin et al	12
those of the	12
lu et al	12
suzuki et al	12
the negative control	12
is consistent with	12
in the two	12
mice from lethal	12
leading to the	12
of three independent	12
binding activity of	12
that had been	12
would not be	12
viral rna synthesis	12
was observed for	12
at the n	12
dub activity of	12
treatment of the	12
in the supernatant	12
active site of	12
d and e	12
the medium was	12
in animal models	12
to identify the	12
daily for days	12
neuman et al	12
purchased from sigma	12
in the united	12
ns a protease	12
development of new	12
by binding to	12
been associated with	12
isolated from the	12
in vero e	12
mutations in the	12
the ratio of	12
in vivo and	12
and subjected to	12
was assessed by	12
and antiviral activity	12
our results suggest	12
the possibility that	12
in the respiratory	12
likely to be	12
the optical density	12
results of the	12
viral infections in	12
of the severe	12
against ebola virus	12
used to determine	12
to confirm the	12
the degree of	12
were performed as	12
the most common	12
the lung slices	12
may interact with	12
u ml penicillin	12
s protein of	12
of patients with	12
compared with that	12
to that in	12
g for min	12
supported by contract	12
of the c	12
study of the	12
bl j mice	12
the plates were	12
activated protein kinase	12
using graphpad prism	12
at mg kg	12
of the other	12
were designed to	12
compounds were added	12
as a model	12
infected with a	12
potent and selective	12
tumor necrosis factor	12
is responsible for	12
the cell membrane	12
deas et al	12
performed in triplicate	12
to the human	12
the immune system	12
the ebn extracts	12
were dissolved in	12
warren et al	12
human coronavirus e	12
mg kg of	12
nature of the	12
washed twice with	12
the virus infection	12
in vivo studies	12
and his residues	12
presence of a	12
for h in	12
well plates at	12
associated with a	12
multiple comparison tests	12
was treated with	11
in this assay	11
the upper respiratory	11
of the hsv	11
of the receptor	11
upper and lower	11
viral titers were	11
chronic hepatitis c	11
for antiviral therapy	11
huang et al	11
the inflammatory response	11
diseases caused by	11
has been suggested	11
ntz and mzr	11
from that of	11
cells were stained	11
addition to the	11
viral rna was	11
are presented as	11
was also observed	11
was added at	11
the dub activity	11
live attenuated influenza	11
supplemented with fbs	11
murine leukemia virus	11
then treated with	11
mrna expression levels	11
in a mouse	11
results indicated that	11
to study the	11
the reaction was	11
ea or la	11
nsp and nsp	11
located in the	11
s and s	11
years of age	11
the risk of	11
at a multiplicity	11
for the control	11
the two compounds	11
virus replication and	11
be involved in	11
transfected with the	11
k akt pathway	11
on day post	11
vero slam cells	11
treatment with a	11
and the results	11
the same time	11
or mg kg	11
virus control group	11
in each group	11
broad range of	11
by flow cytometry	11
were tested in	11
the virus to	11
were observed in	11
school of medicine	11
supernatants were collected	11
members of the	11
human and animal	11
analysis was performed	11
cytotoxicity of the	11
stability of the	11
structures of the	11
it is also	11
well microtiter plates	11
passive transfer of	11
there is an	11
inhibition was observed	11
and lower respiratory	11
up to h	11
in recent years	11
dna and rna	11
contribute to the	11
were performed using	11
against vaccinia virus	11
and cd t	11
inhibits the replication	11
specificity of the	11
it was shown	11
in vivo experiments	11
the hepatitis c	11
of infectious virus	11
entry into the	11
of glycyrrhizic acid	11
structural basis for	11
and then the	11
and replenished with	11
protein in the	11
of feline infectious	11
induction of ifn	11
virus gd protein	11
structure and function	11
plates were incubated	11
the specificity of	11
all of the	11
related to the	11
the introduction of	11
time quantitative pcr	11
of the same	11
peptides derived from	11
emerging and re	11
led to a	11
rift valley fever	11
that it is	11
protein is a	11
two independent experiments	11
virus titer in	11
natural product extracts	11
domain of the	11
is based on	11
play a role	11
and h n	11
by using a	11
cells were mock	11
and mechanism of	11
from the viral	11
were collected and	11
the onset of	11
virus activity of	11
even in the	11
viral dna replication	11
prophylactic and therapeutic	11
replication in cell	11
properties of the	11
mice were infected	11
producing cd t	11
appeared to be	11
treatment of cells	11
required for the	11
mice were treated	11
directed against the	11
this is the	11
this type of	11
african green monkey	11
several studies have	11
associated with severe	11
the cells and	11
ck ch ldl	11
linked immunosorbent assay	11
to the development	11
relative to the	11
is necessary to	11
the viral dna	11
antisense morpholino oligomers	11
interact with the	11
in hela g	11
in c bl	11
is active against	11
of the ppmo	11
and the virus	11
pre post treatment	11
in the upper	11
reported to be	11
was not observed	11
dose of hiltonol	11
expression levels of	11
supplemented with fetal	11
influenza viruses in	11
f infected cells	11
the pathogenesis of	11
with fetal bovine	11
to compare the	11
on the cell	11
virus infections in	11
cytotoxic t lymphocytes	10
red blood cells	10
it may be	10
it is necessary	10
that has been	10
by interfering with	10
used to evaluate	10
t cells and	10
a target for	10
have been described	10
a final concentration	10
was calculated as	10
cells with the	10
inhibition of sars	10
tested for their	10
e and f	10
in our study	10
based on a	10
inhibited replication of	10
of the tested	10
of the f	10
it did not	10
for medical research	10
dmem supplemented with	10
epitopes derived from	10
with pneumonia in	10
is one of	10
pl pro and	10
the range of	10
incubated with the	10
in the elderly	10
cd t cell	10
coronavirus infection in	10
spike protein of	10
of the recombinant	10
immune response to	10
to the control	10
of the genome	10
have the potential	10
den born et	10
was measured at	10
at h pi	10
were determined using	10
leads to the	10
provided by the	10
will be presented	10
a protease activity	10
a relevant peptide	10
n and h	10
of mice were	10
serial dilutions of	10
dose of mg	10
a review of	10
ebola and marburg	10
lungs of mice	10
new class of	10
responsible for the	10
viral replication and	10
due to a	10
rega institute for	10
at different time	10
the authors declare	10
the cause of	10
hcv activity of	10
production of infectious	10
cells were lysed	10
for virus entry	10
were mock infected	10
and stained with	10
are grateful to	10
paavilainen et al	10
results in a	10
rsv vaccine candidates	10
to test the	10
of the family	10
in our previous	10
have also been	10
with respect to	10
ratia et al	10
absence of the	10
the structure and	10
we report the	10
of the respiratory	10
conjugated morpholino oligomers	10
at days post	10
under control of	10
in the cells	10
could not be	10
has to be	10
the cells at	10
were measured by	10
amc dcba and	10
were incubated in	10
as a positive	10
acute otitis media	10
of marburg virus	10
it is known	10
of the three	10
reduction in virus	10
brack et al	10
did not inhibit	10
coronavirus n protein	10
inhibition of hiv	10
syndrome coronavirus in	10
van den born	10
infected with svv	10
levels of p	10
activation of rnase	10
antiviral activities of	10
chan et al	10
co for h	10
the ic values	10
institute for medical	10
immunoprecipitated with anti	10
of viral infections	10
from at least	10
remains to be	10
the need for	10
not affected by	10
a range of	10
used to treat	10
the amc dcba	10
green monkey kidney	10
was confirmed by	10
up and hp	10
we have recently	10
h and then	10
to be highly	10
of celastrol on	10
expression of viral	10
infection in a	10
in the usa	10
was the most	10
that sukumo extract	10
shi et al	10
in the rdev	10
identified as a	10
into the host	10
virus entry and	10
murine hepatitis virus	10
is a major	10
early stage of	10
at the time	10
the action of	10
initiated h after	10
xc plaque reduction	10
is due to	10
evaluation of antiviral	10
washing with pbs	10
carried out using	10
duck enteritis virus	10
were inoculated with	10
reduction at min	10
to block the	10
difference in the	10
with ll of	10
immune responses in	10
been used as	10
han et al	10
rna was isolated	10
to influenza virus	10
analyzed by western	10
genbank accession number	10
the genome of	10
a virus in	10
combination of p	10
was well tolerated	10
in vivo efficacy	10
assay as described	10
molecular mechanisms of	10
there have been	10
pp a cells	10
this suggests that	10
luciferase expressed by	10
of coronavirus n	10
previous studies have	10
with an ec	10
which is a	10
resident memory t	10
using the mtt	10
takeda et al	10
of cells with	10
suggesting that myricetin	10
as a target	10
to this article	10
as a control	10
in inhibition of	10
boriskin et al	10
il tm kopf	10
was found in	10
action of the	10
influenza virus activity	10
the course of	10
a broad range	10
position of the	10
carried out as	10
we tested the	10
f and c	10
of cd t	10
infection of the	10
site in the	10
in vitro activity	10
in the virus	10
for h before	10
food and drug	10
national institutes of	10
on day after	10
be considered as	10
university of michigan	10
was measured with	10
phosphorylation of the	10
bl j scnj	10
causative agent of	10
different time points	10
treatment of sars	10
for detection of	10
of the drug	10
in the placebo	10
in mice immunized	10
a positive control	10
inhibition of influenza	10
of in vitro	10
were stained with	10
novel coronavirus from	10
it is important	10
born et al	10
some of these	10
not seem to	10
attachment to the	10
authors declare no	10
potent in vitro	10
by the host	10
treated cells were	10
the viruses were	10
antiviral activities against	10
that have been	10
of mouse hepatitis	10
of h n	10
it was found	10
at least two	10
with the same	10
viral load in	10
the possibility of	10
is a novel	10
the sequence of	10
surface of liposomes	10
tm kopf j	10
effect on virus	10
to characterize the	10
was calculated using	10
and development of	10
treated with ifn	9
within h of	9
pl pro in	9
the central nervous	9
the potential of	9
lim et al	9
x reaction buffer	9
and its derivatives	9
compounds have been	9
our results showed	9
in a study	9
evaluated for their	9
infected and uninfected	9
the rate of	9
concentration of lm	9
the f l	9
the plasma membrane	9
characterization of a	9
n influenza virus	9
cause of severe	9
mev and sspe	9
of mers coronavirus	9
institutes of health	9
cells were pretreated	9
the causative agent	9
at various concentrations	9
to the same	9
pl pro is	9
treatment of chronic	9
for antiviral research	9
of vacv late	9
ex vivo model	9
day post infection	9
of this compound	9
measured at nm	9
all experiments were	9
research and development	9
as shown by	9
activity against the	9
leneva et al	9
revealed that the	9
applied to compare	9
with the exception	9
was provided by	9
type i and	9
stages of the	9
their antiviral activity	9
treated with a	9
of a number	9
mrna levels of	9
number of cells	9
is composed of	9
in line with	9
of arb against	9
in hepg cells	9
of virus in	9
to virus infection	9
pfu per cell	9
correlated with the	9
has led to	9
of human coronavirus	9
results demonstrated that	9
the purpose of	9
for the study	9
viruses in the	9
seems to be	9
innate immune responses	9
that hp and	9
seem to be	9
a panel of	9
seneca valley virus	9
of luciferase expressed	9
results demonstrate that	9
importance of cholesterol	9
may serve as	9
for inhibition of	9
over the past	9
like protease of	9
served as a	9
with crystal violet	9
only in the	9
or h after	9
surface of the	9
were harvested at	9
cells in vitro	9
in human cells	9
amino acid sequence	9
it has also	9
hcv ns a	9
pl pro by	9
for rsv disease	9
use of a	9
it was also	9
virus in cell	9
were harvested and	9
small interfering rnas	9
culture supernatant was	9
in the inhibition	9
binds to the	9
from pp a	9
resident memory cd	9
phosphorodiamidate morpholino oligomers	9
with different concentrations	9
to calculate the	9
to the surface	9
t to c	9
the samples were	9
protect mice from	9
and young children	9
hepatitis b and	9
crystal structures of	9
the virus inoculum	9
infected with sars	9
of the most	9
of a against	9
acid binding activity	9
lymphocytic choriomeningitis virus	9
cell lines were	9
basu et al	9
virus titers were	9
of the lung	9
s b and	9
structural and functional	9
an attempt to	9
the cytotoxic concentration	9
results show that	9
teissier et al	9
ntd and ctd	9
at an early	9
is thought to	9
resulted in the	9
in cultured cells	9
twice with pbs	9
evaluation of a	9
of antiviral therapy	9
supernatant was measured	9
the most potent	9
utah state university	9
h at room	9
type ii ccov	9
is possible to	9
different from that	9
and infected with	9
as measured by	9
the host immune	9
virus is a	9
of p gag	9
results suggested that	9
at day post	9
a against tgev	9
linked to the	9
it will be	9
analysis revealed that	9
a mixture of	9
each well and	9
global technical meeting	9
structure of sars	9
of the m	9
with influenza a	9
responses in the	9
the yk delta	9
fipv cl pro	9
of the viruses	9
valley fever virus	9
and membrane fusion	9
cell culture and	9
rna was extracted	9
to determine if	9
by influenza virus	9
ec values of	9
day of death	9
higher than those	9
cells were harvested	9
q r on	9
day et al	9
f and g	9
into the cytoplasm	9
effect of chloroquine	9
in the cell	9
not affect the	9
of p mapk	9
infections in immunocompromised	9
deletion of the	9
used to infect	9
not show any	9
as an antiviral	9
cells and the	9
mice were immunized	9
was the first	9
the c s	9
the ntd and	9
wong et al	9
site of the	9
of these agents	9
virus lung titers	9
hcv rna replication	9
the exception of	9
hla class i	9
reduction of viral	9
in the crystal	9
experiments performed in	9
on the virus	9
the establishment of	9
reported to inhibit	9
dependent enhancement of	9
comparison with the	9
accordance with the	9
in rd cells	9
the basis of	9
kumar et al	9
efficacy of a	9
to improve the	9
b virus replication	9
the prevention of	9
were similar to	9
schmidt et al	9
was evaluated in	9
was due to	9
inhibitor of the	9
has been demonstrated	9
is a broad	9
green fluorescent protein	9
the potency of	9
the culture medium	9
zhu et al	9
cells were used	9
is a highly	9
infected with virus	9
respiratory disease in	9
in mammalian cells	9
has been described	9
resistance to the	9
are shown as	9
patients infected with	9
to further characterize	9
cytokine and chemokine	9
of virus infection	9
and sspe virus	9
the mice were	9
or empty vector	9
the national institute	9
tests were applied	9
ex vivo and	9
has recently been	9
of lung slices	9
activity against a	9
interaction of the	9
hhd mice were	9
late gene expression	9
g ml in	9
increase in the	9
independent experiments performed	9
were washed and	9
comparison tests were	9
similar results were	9
was significantly lower	9
significant reduction of	9
found to have	9
in infants and	9
day for days	9
to reduce the	9
h and h	9
howell et al	9
ohno et al	9
science and technology	9
of the vivo	9
are associated with	9
of up to	9
minimum essential medium	9
of neutralizing antibodies	9
viral dna synthesis	9
zheng et al	9
included in the	9
potent antiviral activity	9
the pre post	9
under the control	9
number of plaques	9
provided by dr	9
after washing with	9
been used for	9
of the disease	9
were collected from	9
derived from pp	9
after the virus	9
we conclude that	9
viral infection and	9
were washed three	9
of antiviral agents	9
no evidence of	9
interpretation of the	9
of the sukumo	9
it appears that	9
the extent of	9
free active substances	9
was conducted in	9
luciferase activity was	9
replication in a	9
residues in the	9
absence of k	8
proof of concept	8
a moi of	8
of the mice	8
newcastle disease virus	8
at a dose	8
we are grateful	8
sanchez et al	8
are consistent with	8
the mechanisms of	8
represent the mean	8
review of the	8
c co for	8
in f infected	8
to be an	8
nucleic acid binding	8
and the other	8
activity of celastrol	8
was determined with	8
infection of cells	8
to have antiviral	8
because of their	8
the ebola virus	8
vp and vp	8
limited number of	8
belonging to the	8
that the same	8
as in the	8
with a new	8
and incubated with	8
respiratory tract infection	8
cell cultures and	8
insight into the	8
pp a protein	8
the republic of	8
that bind to	8
model for the	8
functional analysis of	8
is a member	8
a new class	8
to the antiviral	8
of the peptides	8
was propagated in	8
not interfere with	8
there were no	8
p mapk and	8
absorbance at nm	8
in hong kong	8
in health care	8
and it is	8
activity of sukumo	8
were exposed to	8
may also be	8
as the mean	8
at a moi	8
small molecule inhibitors	8
of hiv infection	8
values of ic	8
in cells treated	8
syndrome coronavirus papain	8
was reported to	8
of rsv m	8
of increasing concentrations	8
of small interfering	8
data indicated that	8
was defined as	8
that the inhibitory	8
post treatment group	8
of the efficacy	8
when it was	8
virucidal activity of	8
broad spectrum antiviral	8
infected in the	8
or without myricetin	8
brass et al	8
in the dark	8
is related to	8
into the cell	8
the nucleoside analog	8
with serially diluted	8
institute of virology	8
ml of the	8
to bind to	8
and type ii	8
and jnk phosphorylation	8
of the pd	8
is caused by	8
chu et al	8
the immune response	8
the hypothesis that	8
of these peptides	8
was achieved by	8
be used in	8
by using the	8
necrosis factor alpha	8
inhibit viral replication	8
portion of the	8
identification of the	8
measured by real	8
and drug administration	8
presented as the	8
in x reaction	8
and did not	8
and hp were	8
with l of	8
the viability of	8
the positive control	8
were pretreated with	8
b virus infection	8
results were obtained	8
infected mice were	8
important roles in	8
as inhibitors of	8
to protect against	8
antiviral efficacy of	8
protein was detected	8
ebola virus entry	8
the gp gene	8
lysates were immunoprecipitated	8
a lethal sars	8
absence of a	8
performed using a	8
clr or clr	8
at the viral	8
removed and the	8
in a concentration	8
is an important	8
the viral polymerase	8
significant differences in	8
antiviral drugs and	8
of virus yield	8
are responsible for	8
considered as a	8
from those of	8
a novel mechanism	8
yuan et al	8
the viral entry	8
viral dna polymerase	8
with u ml	8
animal models of	8
volchkov et al	8
designed to target	8
in the field	8
shown in the	8
wide variety of	8
suggesting that it	8
with morpholino oligomers	8
studies on the	8
rinsed with pbs	8
of less than	8
vaccinia virus in	8
at g ml	8
of cytokines and	8
the cell culture	8
that the antiviral	8
room temperature for	8
pan and s	8
before or after	8
structural proteins of	8
for an additional	8
have previously reported	8
was observed when	8
an equal volume	8
with pancreatin f	8
h after virus	8
rnase l was	8
myricetin may interact	8
l in the	8
and la on	8
of at least	8
was shown that	8
treatment was initiated	8
the appearance of	8
replication and transcription	8
that there is	8
in balb c	8
control and prevention	8
as part of	8
to have a	8
in the past	8
may be an	8
based on these	8
selective inhibitor of	8
rna polymerase from	8
antiviral agents against	8
lower than that	8
an ic of	8
centers of excellence	8
inhibitors of sars	8
vero cells with	8
efficacy and safety	8
identified in the	8
of the hiv	8
the s glycoprotein	8
were rinsed and	8
ctl epitopes derived	8
supported by a	8
at lm group	8
inhibitory effect was	8
virus for h	8
infected with junv	8
of more than	8
were prepared by	8
has previously been	8
infants and young	8
by tgev infection	8
for binding to	8
immune responses to	8
cells that were	8
in mice infected	8
thought to be	8
gene expression was	8
ebola virus disease	8
in vitro biochemical	8
of the interferon	8
as described before	8
large number of	8
in phase ii	8
coronavirus associated with	8
derived from a	8
have indicated that	8
were used in	8
for h with	8
early stages of	8
the majority of	8
institute of infectious	8
an attractive target	8
the target of	8
was evaluated using	8
been suggested that	8
replenished with cover	8
acute respiratory infections	8
by plaque reduction	8
of the test	8
determined using the	8
cells grown in	8
supported by grants	8
in this process	8
concentration of drug	8
in the following	8
days post infection	8
effects of ea	8
song et al	8
of the h	8
reduction in the	8
strain ck ch	8
and the development	8
in nonhuman primates	8
cholesterol depletion from	8
was observed at	8
each group were	8
like cleavage site	8
and immunogenic in	8
in the human	8
morpholino antisense oligomers	8
measured by the	8
a wide variety	8
with the cell	8
the culture supernatants	8
titer in the	8
were immunoprecipitated with	8
the interferon system	8
clinical trials for	8
proteins of ibv	8
the past years	8
determined relative to	8
for disease control	8
was determined relative	8
the proportion of	8
the viral replication	8
as a promising	8
lack of a	8
specific cd tem	8
referred to as	8
encoded by the	8
of both antiviral	8
an ec of	8
determine whether the	8
life cycle of	8
varicella zoster virus	8
in a number	8
in the us	8
was performed by	8
it would be	8
in the yk	8
virus life cycle	8
was not affected	8
ic values of	8
from the national	8
drug at lm	8
is expected to	8
influenza viruses and	8
such as influenza	8
the experiments were	8
of nucleotide analogues	8
mediated activation of	8
protein has been	8
studies suggest that	8
the binding affinity	8
mice per group	8
an early stage	8
the placebo group	8
of fipv and	8
in presence of	8
and s proteins	8
with pfu of	8
disease control and	8
it was reported	8
tan et al	8
to understand the	8
viral rna levels	8
the cells with	8
dong et al	8
acyclic nucleoside phosphonates	8
reduction of the	8
virus yield in	8
mg ml griffithsin	8
influenza virus a	8
studies have been	8
prevention and control	8
ns b polymerase	8
and that the	8
was compared with	8
it was not	8
j scnj tlr	8
to show the	8
to infection with	8
were rinsed with	8
challenge with a	8
prepared as described	8
up or hp	8
corresponding to the	8
for the two	8
immunity to the	8
patients with severe	8
ability to inhibit	8
a potential antiviral	8
both ea and	8
be effective in	8
lethal influenza infection	8
as a potent	8
mock infected or	8
for middle east	8
were propagated in	8
was found that	8
strand rna viruses	8
the virus titers	8
is likely to	8
activity was determined	8
tissue culture medium	8
of the interaction	8
is referred to	8
to measure the	8
supernatants of the	8
in some cases	8
after incubation at	8
female balb c	8
may lead to	8
induction of the	8
small interfering rna	8
and uninfected cells	8
on the replication	8
the influenza a	8
this class of	8
with cover layer	8
mean day of	8
caused by a	8
animals and humans	8
coronavirus n proteins	8
of immunized mice	8
to ensure that	8
action of these	8
of balb c	8
of gd protein	8
performed to determine	8
activity against both	8
group at the	8
expression levels were	8
cats with fip	8
were prepared as	8
could be detected	8
to further investigate	8
guo et al	8
cells were further	8
of various concentrations	8
be noted that	8
the numbers of	8
confirmed that the	8
of these drugs	8
attachment and entry	8
experiment was performed	8
in the lower	8
in a cell	8
cloned into the	8
for the drug	8
the first time	8
a virus infection	8
following virus infection	8
target for the	8
to remove the	8
version of this	8
important for the	8
pl pro was	8
is important to	8
approved for treatment	8
when compared to	8
is an urgent	8
and the data	8
removed and cells	8
at which time	8
a functional receptor	8
the media was	8
is a potential	8
as a therapeutic	8
to vero cells	8
equal volume of	8
have antiviral activity	8
termination of the	8
was initiated h	8
bronchoalveolar lavage fluid	8
able to block	7
response to the	7
was incubated at	7
removal of the	7
up to of	7
in vivo with	7
agreement with the	7
the ns a	7
from the ministry	7
of sore throat	7
influenza h n	7
conducted in the	7
inhibitors of hiv	7
the toxicity of	7
a set of	7
well cell culture	7
and the role	7
with virus gd	7
we investigated whether	7
used as negative	7
volume of l	7
stage of the	7
effect of compounds	7
for influenza virus	7
pretreatment with u	7
the rnase l	7
simplex virus glycoprotein	7
analysis of variance	7
infectious diseases of	7
of the peptide	7
to the active	7
he et al	7
virus entry into	7
of the time	7
lungs of immunized	7
mice with a	7
number of viral	7
that the ebn	7
suggesting that these	7
total volume of	7
in vivo models	7
of human parainfluenza	7
xue et al	7
time pcr was	7
in the formation	7
concentrations up to	7
in the online	7
binding domain complexed	7
vsv g protein	7
the percent inhibition	7
three times and	7
blaising et al	7
with virus at	7
viral entry into	7
middle of the	7
in the ebn	7
the integrity of	7
of the p	7
of the infected	7
relevant peptide for	7
of viral proteins	7
be attributed to	7
by the fact	7
and safety of	7
in comparison to	7
experiments were repeated	7
harvested at h	7
protects mice from	7
with tgev at	7
in both the	7
of the total	7
of the binding	7
attributed to the	7
production of interferon	7
did not exhibit	7
the virus life	7
activity on the	7
sodium dodecyl sulfate	7
of two independent	7
of human and	7
peiris et al	7
the viral titers	7
to cells infected	7
protein levels were	7
western blotting assay	7
acts as a	7
depends on the	7
neutrally charged pmos	7
statistical significance was	7
at the position	7
as assessed by	7
these results are	7
of infected mice	7
a total volume	7
the l protein	7
may contribute to	7
at the th	7
infection inhibition of	7
washed once with	7
a high level	7
to cells and	7
n protein is	7
virus in a	7
republic of korea	7
been implicated in	7
agents against influenza	7
groneberg et al	7
to investigate whether	7
cells were first	7
to protect mice	7
have been developed	7
bovine viral diarrhea	7
myricetin may be	7
mouse model of	7
stained with crystal	7
have to be	7
to elucidate the	7
on the basis	7
for another h	7
will be held	7
functional receptor for	7
when cells were	7
propagated in vero	7
peripheral blood mononuclear	7
that the observed	7
were performed by	7
specific inhibitors of	7
levels of cytokines	7
high throughput screening	7
rw peptides were	7
of antiviral research	7
multiple steps of	7
novel coronavirus associated	7
all rights reserved	7
inhibitory effects were	7
an antiviral drug	7
effect of disulfiram	7
been proposed that	7
with this article	7
of c s	7
neutralizing activity against	7
dcba as free	7
simplex virus infection	7
human respiratory syncytial	7
and inhibition of	7
host innate immune	7
was diluted in	7
infections caused by	7
for use as	7
b and table	7
dilutions of the	7
added to vero	7
in well plates	7
a grant from	7
which has been	7
the culture supernatant	7
after days of	7
the distribution of	7
each well was	7
region of interest	7
h in the	7
yu et al	7
under these conditions	7
infection identification of	7
director at the	7
they are not	7
shown by the	7
virus was detected	7
infected with f	7
of ea or	7
syncytial virus and	7
e cells were	7
sars coronavirus spike	7
shoemaker et al	7
the life cycle	7
the early s	7
cells as a	7
could inhibit the	7
concentration of mm	7
in crl cells	7
investigational and experimental	7
leading to a	7
reduction in prrsv	7
the initial velocity	7
by confocal microscopy	7
protein of the	7
used to analyze	7
infected cells and	7
inflammatory effects in	7
hohdatsu et al	7
the difference in	7
at the post	7
were further incubated	7
the middle of	7
fold reduction in	7
expressed as the	7
binding domain of	7
rsv m epitope	7
cells using the	7
effects of u	7
of hiv replication	7
carried out in	7
plays a role	7
cell spread of	7
is the only	7
respect to the	7
agarose gel electrophoresis	7
in cells infected	7
the upper and	7
effect was observed	7
we report a	7
play important roles	7
was performed on	7
at different times	7
ratio of cd	7
these compounds are	7
for the sars	7
cell responses in	7
time of addition	7
sialic acid binding	7
onset of symptoms	7
from patients with	7
i ifn production	7
of griffithsin on	7
syndrome virus replication	7
treatment of hsv	7
of sialic acids	7
report on the	7
modification of the	7
rnase l pathway	7
response to viral	7
in animals and	7
lupfer et al	7
cell cultures with	7
case of the	7
of viral dna	7
was performed at	7
that pedv pl	7
carried out with	7
drosten et al	7
the search for	7
for three times	7
have proven to	7
and influenza a	7
used to study	7
with the viral	7
the highly conserved	7
the percentages of	7
was incubated for	7
did not induce	7
virus and the	7
from infected cells	7
binding site of	7
was observed with	7
for five days	7
the efficacy and	7
were removed and	7
highly pathogenic human	7
treatment of human	7
the position of	7
spleen cells of	7
cells were co	7
agents have been	7
and chemokines in	7
effect of z	7
are urgently needed	7
expression of cd	7
of african horse	7
the spread of	7
used at a	7
viral respiratory infections	7
percentage of the	7
virus yield inhibition	7
along with the	7
has been found	7
in the c	7
against a variety	7
laiv ns rsv	7
in a previous	7
activation of p	7
h of incubation	7
cells were maintained	7
act as a	7