Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-253825-d9borky8a broad- spectrum antiviral compound that blocks viral fusion Arbidol: a broad- spectrum antiviral that inhibits acute and chronic HCV infection Similar uptake but different trafficking and escape routes of reovirus virions and ISVPs imaged in polarized MDCK cells Design of inhibitors of influenza virus membrane fusion: synthesis, structure- activity relationship and in vitro antiviral activity of a novel indole series Antiviral activity of arbidol, a broad- spectrum drug for use against respiratory viruses, varies according to test conditions Antiviral chemotherapeutic agents against respiratory viruses: where are we now and what's in the pipeline?
cord-255536-x1z2o9gsTargeting G- quadruplexes in gene promoters: a novel anticancer strategy?
cord-277443-mv7sk5aaDid this apparent moderation of the inflammatory response both in the lungs and on the surface of the lungs due correlate with a reduction of virus replication in the lungs of infected mice, the presence of virus protein the likely culprit for inducing edema?
cord-260735-3c33r1osFree Radic Nuclear factor kappa B: a potential target for anti- HIV chemotherapy Efficacy of therapeutic intervention with an oral ether- lipid analogue of cidofovir( CMX001) in a lethal mousepox model Is alpha- lipoic acid a scavenger of reactive oxygen species in vivo?
cord-284076-087oltssTargeted'knockdown'of channel expression in vivo with an antisense morpholino oligonucleotide Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models Molecular characterization of porcine reproductive and respiratory syndrome virus, a member of the arterivirus group Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication VP35 knockdown inhibits ebola virus amplification and protects against lethal infection in mice Inhibition of multiple subtypes of Influenza A virus in cell cultures with morpholino oligomers Morpholino oligos: making sense of antisense?
cord-023608-w2g7v7g1Or perhaps the( immuno)pathology of virus infections may boost some specific enzyme reactions in the infected organs?
cord-023608-w2g7v7g1So perhaps it is time to consider some less explored scaffolds in the search for new nucleos(t)ide antivirals?
cord-023608-w2g7v7g1Why is then the structural diversity of antiviral nucleos(t)ide drugs still quite limited?
cord-328468-bwn4bmf5B8R protein Inhibition of vaccinia virus entry by a broad spectrum antiviral peptide Antiviral peptides targeting the west nile virus envelope protein Novel influenza virus NS1 antagonists block replication and restore innate immune function Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
cord-308110-cco3aq4nA review of the safety of favipiravir-a potential treatment in the COVID-19 pandemic?
cord-312688-12san3m7The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-312965-5hcb15xcAntiviral treatment for chronic hepatitis B virus infection- immune modulation or viral suppression?
cord-288337-sw7xjpbrWhy could the EBN extract inhibit infection of recently isolated influenza viruses?
cord-310469-v4p01rzeType I human interferons equivalent?
cord-298166-045evk7gA novel"molecular tweezer"inhibitor of α- synuclein neurotoxicity in vitro and in vivo Zika virus and birth defects- reviewing the evidence for causality A molecular tweezer ameliorates motor deficits in mice overexpressing α- synuclein Macromolecular antiviral agents against Zika, Ebola, SARS, and other pathogenic viruses Molecular tweezers for lysine and arginine- powerful inhibitors of pathologic protein aggregation Ebola vaccine: how far are we?
cord-336093-ic6q6ke8Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene Flaviviral methyltransferase/ RNA interaction: structural basis for enzyme inhibition Discovery of an RNA virus 3 0?
cord-329642-5t8yuq4verythematosus Human coronavirus EMC does not require the SARScoronavirus receptor and maintains broad replicative capability in mammalian cell lines Reduction of immune activation with chloroquine therapy during chronic HIV infection Monoclonal antibodies to the spike protein of feline infectious peritonitis virus mediate antibody- dependent enhancement of infection of feline macrophages Chloroquine administration does not prevent Nipah virus infection and disease in ferrets A review of feline infectious peritonitis virus infection: 1963- 2008 Immunologic phenomena in the effusive form of feline infectious peritonitis Activation of p38 MAPK by feline infectious peritonitis virus regulates pro- inflammatory cytokine production in primary blood- derived feline mononuclear cells Effect of feline interferon- omega on the survival time and quality of life of cats with feline infectious peritonitis Effects of chloroquine on viral infections: an old drug against today's diseases?
cord-316503-wtmmewizantisense or anti- protein?
cord-314833-6fue84x6} Are weak protein- protein interactions the general rule in capsid assembly?
cord-332952-d5l60cgcWhy did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
cord-298938-xemarhlvCleavage of the divergent domains of ribosomal RNA in apoptosis Chronic hepatitis A with persistent viral replication Replication of hepatitis A viruses with chimeric 5 nontranslated regions 70 Specific proteolytic cleavage of poly(ADP- ribose) polymerase- an early marker of chemotherapy- induced apoptosis Cleavage of poly( A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: another mechanism for host protein synthesis shutoff?
cord-298938-xemarhlvFine mapping of 28S rRNA sites specifically cleaved in cells undergoing apoptosis Divergence towards a dead end?
cord-316996-8yimrpazMicrobiol Microbial sialidases: does bigger always mean better?
cord-316996-8yimrpazThe human Cas1 protein: a sialic acid- specific Oacetyltransferase?
cord-292830-gcfx1095; could statins fill gap?
cord-292830-gcfx1095A DNA transfection system for generation of influenza A virus from eight plasmids Pleiotropic mechanisms of ribavirin antiviral activities Emerging virus diseases: can we ever expect the unexpected?
cord-285505-8norumv6: What opportunity exists for a better nucleoside/ nucleotide to treat hepatitis C?
cord-285505-8norumv6In contrast, there was far less protection in clinical trials-why?
cord-285505-8norumv6Is it possible that raltegravir is inducing a single round of HIV replication, to give an increase in HIV circles?
cord-285505-8norumv6What is the role of T- cell responses?
cord-278876-il7g78w1Characterization of the human papillomavirus( HPV) integration sites into genital cancers Lethal mutagenesis of hepatitis C virus induced by favipiravir Virus and host factors affecting the clinical outcome of bluetongue virus infection Ongoing clinical trials of human immunodeficiency virus latency- reversing and immunomodulatory agents Is virology dead?
cord-278876-il7g78w1Is microcephaly among some neonates just the tip of the neurological iceberg?
cord-278876-il7g78w1When and how should infants be tested for possible congenital Zika infection?
cord-278876-il7g78w1Why does the overall risk of microcephaly and other birth defects seem to differ in other parts of Latin America and the Caribbean, compared to Brazil?
cord-278876-il7g78w1straight or cocktail?
cord-281385-oxohdfpuGpppN- RNA);( iii) an N-7 methyltransferase( MTase) methylates the guanine N-7 position to produce m7GpppN- RNA( GpppN- RNA? m7GpppN);( iv)
cord-281385-oxohdfpuMTase methylates the ribose 2 0-O position of the RNA to complete the type-1 cap formation( m7GpppN- RNA?
cord-281385-oxohdfpuNS5 Live attenuated vaccine: the first clinically approved dengue vaccine?
cord-281385-oxohdfpuan RNA triphosphatase removes the c- phosphate from the 5 0 triphosphate of the nascent RNA( pppN- RNA? ppN- RNA);( ii) an RNA guanylyltransferase( GTase) transfers the GMP moiety from GTP to ppN- RNA to generate GpppN- RNA( GTP+ ppN- RNA?
cord-281385-oxohdfpuan RNA triphosphatase removes the c- phosphate from the 5 0 triphosphate of the nascent RNA( pppN- RNA? ppN- RNA);( ii) an RNA guanylyltransferase( GTase) transfers the GMP moiety from GTP to ppN- RNA to generate GpppN- RNA( GTP+ ppN- RNA?
cord-008716-38sqkh9mAre there immunological consequences of passive immunoprophylaxis?
cord-008716-38sqkh9mCytotoxic T- cell immunity to influenza Does prematurity alter the course of respiratory syncytial virus infection?
cord-008716-38sqkh9mGiven these experiences, could we expect another new strain to behave differently today?
cord-008716-38sqkh9mNegative- strand virus M and retrovirus MA proteins: all in a family?
cord-008716-38sqkh9mPrevalence of various respiratory viruses in the middle ear during acute otitis media A longitudinal study of respiratory viruses and bacteria in the etiology of acute otitis media with effusion Recovery of a new agent from patients with acute respiratory disease Characterization of the influenza A virus gene pool in avian species in southern China: was H6N1 a derivative or a precursor of H5N1?
cord-008716-38sqkh9mThe IMpact- RSV Study Group Molecular characterization of H9N2 influenza viruses: were they the donors of the'internal'genes of H5N1 viruses in Hong Kong?
cord-008716-38sqkh9mWhat are our options for vaccination against potentially pandemic viruses?
cord-008716-38sqkh9mWhat are the general principles underlying vaccine development for these viruses?
cord-008716-38sqkh9mWhat are the viruses with pandemic potential?
cord-008716-38sqkh9mWhat quantity of antiviral drugs is available for emergency use?
cord-008716-38sqkh9mWhich vaccines are available?