trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	166
the number of	162
supplementary table s	139
in this study	106
the presence of	106
based on the	102
severe acute respiratory	98
acute respiratory syndrome	96
respiratory syndrome coronavirus	95
and bat cov	77
we found that	74
in order to	73
at room temperature	69
and supplementary fig	68
in supplementary table	66
structure of the	65
due to the	64
was used to	63
rs rs rs	63
in addition to	62
extended data fig	62
a total of	58
analysis of the	56
according to the	56
in the lungs	56
the role of	54
in response to	54
of the sars	54
was used for	52
human sars cov	52
for min at	51
was performed using	50
consistent with the	49
compared to the	49
one of the	49
the expression of	48
each of the	46
for h at	45
of the s	45
as previously described	45
the d tetra	44
were used to	44
was used as	43
the evolution of	42
crystal structure of	42
thermo fisher scientific	41
the absence of	40
ifitm double null	39
ifitm ifitm double	39
is consistent with	39
used as a	39
in the presence	39
cb infected mice	39
in the d	38
been shown to	38
supplementary figure s	37
of the human	36
the development of	36
supplementary information fig	35
of the virus	35
cells in the	35
and supplementary table	35
was added to	34
vips and non	34
associated with the	34
shown in supplementary	33
included in the	33
ace and tmprss	33
creative commons license	33
of severe acute	32
as shown in	32
observed in the	32
in supplementary fig	32
were incubated with	31
the majority of	31
the fact that	31
the importance of	30
members of the	30
as described above	30
we used the	30
a set of	30
to determine the	30
found to be	30
added to the	30
new york city	30
in terms of	29
the active site	29
it has been	29
data not shown	29
a number of	29
most of the	28
for statistical analysis	28
igg and igm	28
of human sars	28
involved in the	28
the amount of	28
total number of	28
the use of	28
the structure of	27
the genomes of	27
end of the	27
the total number	27
s and s	27
excess of adaptation	27
changes in the	27
east respiratory syndrome	27
used for statistical	27
middle east respiratory	26
of adaptation in	26
the proportion of	26
on the other	26
ifitm and ifitm	26
we sought to	26
with the same	26
the great leaf	26
the analysis of	26
the case of	26
shown to be	26
has been shown	25
the identification of	25
analysis was performed	25
the authors declare	25
that can be	25
in the human	25
the rate of	25
a variety of	25
as a result	25
the difference in	25
egyptian fruit bat	25
in the absence	25
to assess the	25
part of the	25
genes involved in	25
in line with	25
of purifying selection	24
the other hand	24
a subset of	24
the binding of	24
of the three	24
the context of	24
of the most	24
predicted to be	24
for each of	24
at least one	24
from the same	24
well as the	24
with regard to	24
characterization of a	24
in the same	24
all three viruses	24
was carried out	23
present in the	23
is associated with	23
the effects of	23
in the ifitm	23
double null cells	23
used in this	23
in all three	23
the lack of	23
were obtained from	23
the impact of	22
showed that the	22
is required for	22
in the genomes	22
to investigate the	22
to interact with	22
human sars and	22
in sphere culture	22
in the context	22
all of the	22
a and supplementary	22
to identify the	22
of the viral	22
genes in the	22
the effect of	22
as described previously	22
to be a	22
related to the	21
chinese rufous horseshoe	21
responsible for the	21
regions of the	21
available in the	21
role in the	21
be due to	21
a result of	21
differentially expressed genes	21
have shown that	21
information is available	21
the severe acute	21
of this study	21
revealed that the	21
the genome of	21
it is possible	21
in the case	21
the distribution of	21
and in the	21
such as the	21
of the two	21
of the complex	21
a shared ride	21
materials and methods	21
components of the	21
table and supplementary	20
the end of	20
addition to the	20
the samples were	20
and characterization of	20
used for the	20
rufous horseshoe bat	20
standard sphere culture	20
of bat cov	20
we used a	20
compared with the	20
characterization of the	20
expression of the	20
the supplementary material	20
in vitro and	20
with respect to	20
test was used	20
likely to be	20
of the p	20
we did not	19
found in the	19
wide range of	19
a combination of	19
a wide range	19
that of the	19
was observed in	19
has been reported	19
this study are	19
different types of	19
suggests that the	19
the addition of	19
of the protein	19
in ercc l	19
mhc class i	19
expression of ace	19
were performed using	19
found that the	19
at the same	19
of the genes	19
the incorporation of	18
performed using the	18
permutation test p	18
authors declare no	18
gene set enrichment	18
some of the	18
the level of	18
dissolved organic matter	18
the replication of	18
way anova with	18
difference in the	18
are shown in	18
specific antibody responses	18
were identified in	18
in at least	18
a range of	18
were used for	18
were purchased from	18
compared to non	18
sphere cell culture	18
the results of	18
in the brain	18
pn ps ratio	18
of the total	18
see supplementary material	18
to that of	18
differences in the	18
the s trimer	18
we show that	18
we performed a	17
of ercc l	17
identified in the	17
there is a	17
region of the	17
member of the	17
associated with a	17
the egyptian fruit	17
of the affected	17
shared ride requests	17
of all three	17
can be found	17
in larp mutants	17
contribute to the	17
detected in the	17
in complex with	17
of group ilcs	17
in agreement with	17
any of the	17
the supernatant was	17
the most abundant	17
mm hepes ph	17
the chinese rufous	17
derived from the	17
following treatment with	17
suggesting that the	17
the fraction of	17
similar to the	17
the lungs of	17
it is also	17
were carried out	17
was extracted from	17
the sars coronavirus	17
as shown by	17
obtained from the	16
was incubated with	16
energy of the	16
mrnas that encode	16
was applied to	16
supplementary table and	16
based on a	16
of a novel	16
is possible that	16
the s subunit	16
the copyright holder	16
of the same	16
to have a	16
vesicular stomatitis virus	16
as infected mice	16
between the two	16
was obtained from	16
sars and bat	16
show that the	16
in the supplementary	16
represented sequences in	16
declare no competing	16
the treatment of	16
used in the	16
bat cov are	16
multiple sequence alignment	16
broad range of	16
this paper at	16
sequences in the	16
land degradation neutrality	16
that have been	16
there is no	16
supplementary material online	16
information table s	16
be involved in	16
supplementary information table	16
binding of the	16
of minor variants	16
in our study	16
which can be	16
be used to	16
in liquid nitrogen	16
were used as	16
a broad range	16
adoption of ride	16
is essential for	15
variation in the	15
used as the	15
the data in	15
referred to as	15
the formation of	15
in inflamed lungs	15
nsp s from	15
data in supplementary	15
and subjected to	15
ace expression in	15
positive selection in	15
in supplementary information	15
is one of	15
levels of the	15
of the host	15
structural and functional	15
under positive selection	15
was performed in	15
study are available	15
compared to wt	15
in the high	15
min at room	15
genes under selection	15
a function of	15
in the main	15
in the population	15
proteins of sars	15
sequences that are	15
the ability of	15
the course of	15
adaptation in vips	15
corresponding to the	15
each of these	15
large flying fox	15
in accordance with	15
the set of	15
as a function	15
b and supplementary	15
were added to	15
and in vivo	15
a and b	15
in new york	15
were treated with	15
conjugated goat anti	15
coronavirus spike protein	15
can be used	15
high levels of	15
pps and mlns	15
are associated with	15
is available in	15
the rest of	15
at xg for	15
role of the	15
of these viruses	15
were calculated using	15
people with ds	15
closely related to	15
proteins involved in	15
vitro and in	15
side of the	15
that ercc l	15
an increase in	15
not included in	15
host genomic diversity	15
sequence of the	15
many of the	15
to understand the	15
as and cb	15
understanding of the	15
g for min	15
based on their	15
are predicted to	15
in this article	15
was performed by	14
ace tmprss cells	14
provided in supplementary	14
supplementary tables and	14
structural basis for	14
in supplementary figure	14
in the lung	14
approved by the	14
listed in supplementary	14
regard to jurisdictional	14
are listed in	14
consistent with previous	14
the intrinsic disorder	14
infusion of nt	14
cells were grown	14
are likely to	14
xg for minutes	14
use of the	14
data suggest that	14
could not be	14
room temperature for	14
that are not	14
the sepsis timeline	14
remains neutral with	14
the university of	14
and smoking status	14
neutral with regard	14
maps and institutional	14
claims in published	14
to evaluate the	14
are represented as	14
h at room	14
the function of	14
be found in	14
cells were washed	14
were used in	14
an enabling environment	14
rna was extracted	14
with the highest	14
to determine whether	14
the d bioprinted	14
published maps and	14
the amino acid	14
features of the	14
jurisdictional claims in	14
from human sars	14
and institutional affiliations	14
double null cell	14
in published maps	14
the dn ds	14
paper at https	14
described in the	14
ifitm single null	14
at o c	14
target of rapamycin	14
li et al	14
in human sars	14
error bars represent	14
indicated that the	14
gscs in the	14
it can be	14
supplementary information figs	14
nature remains neutral	14
was defined as	14
carried out in	14
provided by the	14
protein of sars	14
of positive selection	14
the s protein	14
in pbs for	14
to jurisdictional claims	14
were able to	14
the surface of	14
enabling environment for	14
see supplementary table	14
shown in fig	14
the ratio of	14
of the vsv	14
were found to	14
are provided in	14
the sum of	14
be explained by	14
springer nature remains	14
and supplementary information	13
in the first	13
frozen in liquid	13
evolution of the	13
washed three times	13
orf b protein	13
the cells were	13
as described in	13
of the model	13
in the analysis	13
the most common	13
in ml of	13
and stored at	13
cells were incubated	13
mouse model of	13
two independent sgrnas	13
vs sphere cell	13
data indicate that	13
an important role	13
influenza a virus	13
nosed bat and	13
of intrinsic disorder	13
in cb infected	13
amino acid sequences	13
by morfchibi web	13
of the spike	13
dn ds ratio	13
tend to be	13
to the original	13
identification of the	13
binding residues in	13
ray crystal structure	13
the type of	13
in both the	13
in the coding	13
unless indicated otherwise	13
the ace receptor	13
were generated using	13
we use the	13
data are represented	13
this suggests that	13
the ifitm ifitm	13
the pn ps	13
c and supplementary	13
more than one	13
was performed with	13
limit of detection	13
the average number	13
findings of this	13
of the number	13
in which the	13
to calculate the	13
is an important	13
and orf b	13
are required for	13
group ilcs and	13
have been shown	13
were found in	13
are included in	13
large number of	13
fraction of the	13
the percentage of	13
with two independent	13
this study was	13
cells of the	13
with the following	13
the length of	13
of the active	13
size of the	13
to estimate the	13
the time of	13
due to their	13
but not in	13
dom molecular formulae	13
we also found	13
of the viruses	13
the findings of	13
interact with the	13
transgenic chicken embryos	12
were incubated at	12
single cell suspensions	12
rest of the	12
amino acid substitutions	12
which may be	12
three times with	12
are involved in	12
the cleavage site	12
resulted in a	12
generated using the	12
the cell surface	12
been reported to	12
of ace and	12
proteins that are	12
is based on	12
are available from	12
suggest that the	12
pile and pilv	12
of these two	12
of neisseria meningitidis	12
in contrast to	12
of the n	12
known to be	12
activity of bace	12
of rna viruses	12
independent sgrnas targeting	12
at the time	12
are present in	12
acute respiratory distress	12
was measured using	12
little brown bat	12
the log transformed	12
in the dorsal	12
to the same	12
each cell type	12
previous studies have	12
and incubated for	12
results from the	12
may also be	12
a member of	12
for details on	12
these data are	12
insight into the	12
were calculated by	12
in the database	12
creative commons attribution	12
no competing interests	12
comparison of the	12
results suggest that	12
the host cell	12
on the same	12
see supplementary information	12
using the same	12
balb c mice	12
proteins in the	12
of selected codons	12
of the genome	12
for the first	12
for the treatment	12
of the body	12
of the supplementary	12
were infected with	12
of the rna	12
was set to	12
the prevalence of	12
and supplementary figure	12
the limit of	12
the financial incentives	12
in the original	12
supported by the	12
supplementary material for	12
of gene expression	12
in the dark	12
in this work	12
the viral genome	12
the size of	12
as determined by	12
as long as	12
for the sars	12
for minutes at	12
then added to	12
the main manuscript	12
is not included	12
of shared ride	12
as a control	12
we conclude that	12
of the hcov	12
length of the	12
a role in	12
copy of this	12
or a sgcont	12
be associated with	12
insights into the	12
as defined by	12
respiratory distress syndrome	12
in the great	12
transferred to a	12
were centrifuged at	12
required for the	12
of size m	12
and the number	12
the predicta chip	12
the possibility that	11
exceeds the permitted	11
material is not	11
was performed on	11
or other third	11
is likely to	11
seedlings compared to	11
we believe that	11
new england biolabs	11
in any medium	11
your intended use	11
calculated by the	11
indicated otherwise in	11
the emergence of	11
d bioprinted tetra	11
demonstrated that the	11
to view a	11
in standard sphere	11
in the dg	11
need to obtain	11
otherwise in a	11
of the tl	11
structure of a	11
medium or format	11
binding domain of	11
the vast majority	11
of the capsid	11
considered to be	11
permission directly from	11
changes were made	11
of sars coronavirus	11
to the creative	11
amino acid changes	11
the creative commons	11
indicated by the	11
the combination of	11
important role in	11
images or other	11
credit to the	11
the significance of	11
were resuspended in	11
link to the	11
not permitted by	11
determined by the	11
material in this	11
this means that	11
the production of	11
development of a	11
vips with similar	11
of the global	11
a concentration of	11
msa of sars	11
other third party	11
to obtain permission	11
have been reported	11
dependent rna polymerase	11
with or without	11
a credit line	11
of the predicted	11
party material in	11
in pps and	11
by the presence	11
line to the	11
are known to	11
buffer containing mm	11
via verso step	11
or exceeds the	11
we have previously	11
and reproduction in	11
the images or	11
were present in	11
supplementary tables s	11
calculated using the	11
the spike protein	11
for h in	11
than that of	11
was performed as	11
available from the	11
there were no	11
in at cells	11
appropriate credit to	11
dna binding residues	11
of top mrnas	11
for min and	11
of clonal variants	11
h n virus	11
weeks after stroke	11
is involved in	11
on ice for	11
top mrnas in	11
higher level of	11
licensed under a	11
this article are	11
a link to	11
which permits use	11
gscs in sphere	11
class i molecules	11
regulation or exceeds	11
shown in the	11
is licensed under	11
commons license and	11
bound to the	11
as compared to	11
the age of	11
in pn ps	11
seq data sets	11
it is not	11
in the blood	11
out of the	11
genes that are	11
at the end	11
the immune system	11
data from the	11
a copy of	11
and ifitm ifitm	11
the numbers of	11
of the lungs	11
a mouse model	11
positive cells in	11
access this article	11
s s s	11
see supplementary document	11
binding to the	11
of the data	11
any medium or	11
whitney u test	11
as you give	11
the p gene	11
table of the	11
distribution and reproduction	11
and the chinese	11
the permitted use	11
the activity of	11
and the source	11
you will need	11
the original author	11
as previously reported	11
were grown in	11
give appropriate credit	11
credit line to	11
rpm for min	11
of the proteins	11
can also be	11
available in supplementary	11
the mechanism of	11
indicate if changes	11
variants of the	11
is not permitted	11
in a credit	11
has not been	11
and indicate if	11
the existence of	11
of the other	11
third party material	11
were transfected with	11
of ace in	11
sequence identity with	11
cells were transfected	11
with human sars	11
the same time	11
stimulation of the	11
supplementary information for	11
b and c	11
of amino acids	11
we observed that	11
is available at	11
article is licensed	11
and incubated at	11
the immune response	11
the concentration of	11
in the following	11
to this end	11
relative to the	11
as or cb	11
by statutory regulation	11
of these genes	11
we were able	11
permitted by statutory	11
license and your	11
to the material	11
experiments were performed	11
are available in	11
if material is	11
you give appropriate	11
cell viability of	11
statutory regulation or	11
in the microcosms	11
the coding regions	11
bat cov nsp	11
from the copyright	11
vips compared to	11
a creative commons	11
under a creative	11
in the host	11
permanent social isolation	11
there was a	11
type iv pilus	11
use is not	11
obtain permission directly	11
open access this	11
org licenses by	11
of this license	11
majority of the	11
adaptive evolution in	11
provide a link	11
basis for the	11
see supplementary fig	11
long as you	11
this article is	11
directly from the	11
intended use is	11
at least two	11
to be the	11
a large number	11
the regulation of	11
reproduction in any	11
article are included	11
view a copy	11
a receptor for	11
if changes were	11
sequences of the	11
consistent with our	11
we compared the	11
protein interaction networks	11
distribution of the	11
and your intended	11
will need to	11
the characterization of	11
messer and petrov	11
all of these	10
and error bars	10
we find that	10
there was no	10
supplementary material s	10
functions of the	10
asymptotic mk test	10
that uses the	10
human coronavirus e	10
version of the	10
with dunnett multiple	10
was determined by	10
this is consistent	10
the elevation of	10
influenza a viruses	10
mutations in the	10
studies of the	10
pcr products were	10
values were calculated	10
to detect the	10
is available for	10
were analyzed by	10
was found to	10
which is a	10
should be addressed	10
in the ncbi	10
of or genes	10
on the surface	10
a phylogenetic tree	10
were generated by	10
anova with dunnett	10
shows that the	10
supplementary figure a	10
treatment with two	10
incubated with the	10
intrinsic disorder in	10
shown by the	10
socially isolated mice	10
note springer nature	10
was transferred to	10
environment for ldn	10
protein sequences of	10
vast majority of	10
york city and	10
a and orf	10
to those of	10
set enrichment analysis	10
for each bat	10
were detected in	10
of chronic stress	10
ifitm protein expression	10
rna and dna	10
signals of adaptation	10
structure of human	10
higher than the	10
average number of	10
number of under	10
o c for	10
cloned into the	10
the first time	10
increase in the	10
then incubated with	10
high level of	10
was then added	10
to model the	10
applied to the	10
s from sars	10
s and supplementary	10
the sequence of	10
be addressed to	10
for the analysis	10
in a mouse	10
were isolated from	10
bat and the	10
in the number	10
residues that are	10
sites in the	10
interaction with the	10
it is important	10
vips with the	10
as the biocatalyst	10
is the only	10
ercc l is	10
multiple test correction	10
before and after	10
selection in the	10
orf a and	10
is predicted to	10
the novel coronavirus	10
figure and supplementary	10
and ifitm proteins	10
the affected forelimb	10
were grouped into	10
which is the	10
positive cell density	10
regulated by tor	10
cytosolic rp mrnas	10
used to identify	10
vs gscs in	10
in the ventral	10
in the s	10
compared to other	10
interactions between the	10
in the directon	10
to the high	10
domain of the	10
to the human	10
cells were harvested	10
c and c	10
from all three	10
were associated with	10
of the egyptian	10
is due to	10
may be due	10
a reduction in	10
in more than	10
residues in the	10
and in vitro	10
and requests for	10
details on the	10
correspondence and requests	10
play a role	10
nt and vehicle	10
amino acid residues	10
shown in figure	10
used to generate	10
were determined by	10
log fold change	10
philippe et al	10
between vips and	10
protein from sars	10
and functional characterization	10
was performed to	10
is the number	10
using imagej software	10
our estimates of	10
human sars nsp	10
results indicate that	10
for each gene	10
functional characterization of	10
may contribute to	10
a fraction of	10
were stored at	10
supplementary figure b	10
accordance with the	10
is important to	10
pn ps is	10
with that of	10
of these proteins	10
needs to be	10
of nsp s	10
terminal region of	10
a series of	10
of pseudotyped mers	10
in our dataset	9
was supported by	9
the large flying	9
the genome sequences	9
bat cov and	9
performed as described	9
and can be	9
increased expression of	9
gscs grown in	9
the microcosms with	9
proportional to the	9
that do not	9
we hypothesized that	9
their ability to	9
for the development	9
and multiciliated cells	9
to this article	9
was determined using	9
significant differences in	9
genome of the	9
zhang et al	9
along with the	9
reconstruction of the	9
represented in the	9
genomes of the	9
acute stress exposure	9
the negative set	9
the phylogenetic tree	9
the peptides were	9
or absence of	9
the domestic cat	9
of olfactory receptor	9
were prepared using	9
for this paper	9
this is the	9
chemosensory receptor genes	9
each sample was	9
the likelihood function	9
table s and	9
tgev and prcv	9
when compared with	9
em structure of	9
the activation of	9
change of the	9
differential gene expression	9
of the rbd	9
the wt rnap	9
been shown that	9
permission information is	9
has previously been	9
given in supplementary	9
were expressed in	9
and incubated with	9
we investigated the	9
the online version	9
to our knowledge	9
complex with the	9
in a single	9
to the s	9
to explore the	9
are characterized by	9
the other two	9
of the association	9
purifying selection in	9
the design of	9
open reading frame	9
random variants of	9
and found that	9
for materials should	9
p after iterations	9
and igm responses	9
was used in	9
mean ppids of	9
kindly provided by	9
the efficiency of	9
a single dose	9
the rhinolophoid bats	9
of known acrs	9
receptor for the	9
is found to	9
in mammalian cells	9
in the second	9
false discovery rate	9
the n protein	9
the recognition of	9
the excess of	9
ranked in first	9
in humans and	9
number of non	9
and permission information	9
the detection of	9
of coronavirus disease	9
as illustrated in	9
response to the	9
requests for materials	9
land use planning	9
the observation that	9
have the same	9
vero e cells	9
the strength of	9
a resolution of	9
neutrophils in the	9
protein binding regions	9
terms of the	9
those in the	9
by verso step	9
mrna expression signature	9
to bind to	9
were analyzed using	9
range of mammals	9
respect to the	9
groups based on	9
significance of the	9
a measure of	9
with ml of	9
hours after stroke	9
to improve the	9
we speculate that	9
of the mammalian	9
in the future	9
a decrease in	9
fold increase in	9
supplementary file c	9
there is an	9
materials should be	9
by flow cytometry	9
did not show	9
type iv pili	9
serial dilutions of	9
we also observed	9
for kawasaki disease	9
gene expression and	9
specific igg and	9
in patients with	9
by the wild	9
the d tri	9
viruses and the	9
the robustness of	9
cov and sars	9
in each of	9
to define the	9
after acute stress	9
analyses for the	9
and the other	9
reprints and permission	9
of cb infected	9
were washed with	9
do not have	9
data collection and	9
we assume that	9
we observed a	9
genes related to	9
to compare the	9
incorporation of the	9
allowed us to	9
post hoc p	9
as an important	9
correlation between the	9
different time points	9
to the data	9
the r package	9
probability of activation	9
protein is a	9
the loss of	9
correlated with the	9
to ensure that	9
final concentration of	9
development of the	9
a previous study	9
to limit the	9
cov nsp proteins	9
acylated steroidal glycosides	9
nature of the	9
receptor binding domain	9
was generated by	9
the adoption of	9
to confirm the	9
observed that the	9
to characterize the	9
in supplementary data	9
to be highly	9
of plasmodium falciparum	9
based on our	9
by using a	9
mapped to the	9
conformation of the	9
have not been	9
can be infected	9
the lbcas a	9
in the open	9
of the dn	9
for the great	9
in first place	9
figure s a	9
of the samples	9
available for this	9
for receptor binding	9
lower than the	9
that may be	9
were incubated for	9
a new coronavirus	9
of b cells	9
of the major	9
as described before	9
reaction mixture was	9
also known as	9
at the c	9
review of the	9
fact that the	9
at time t	9
expressed in the	9
in bat cov	9
number of requests	9
in injured lungs	9
authors declare that	9
to match the	9
the influence of	9
in bat species	9
expression signature of	9
bovine serum albumin	9
in the n	9
to analyze the	9
the finding that	9
phylogenetic analysis of	9
of viral rna	9
sphere culture vs	9
in all the	9
raw sequencing data	9
were selected for	9
is the first	9
of the tor	9
vips with a	9
its interaction with	9
of mrnas that	9
can lead to	9
centrifuged at xg	8
a model of	8
h n challenge	8
pathogenic avian influenza	8
in the acute	8
nsp s are	8
of people with	8
third copy of	8
version of this	8
information for details	8
the proportions of	8
the origin of	8
serve as a	8
to the corresponding	8
these results indicate	8
at a concentration	8
all three studied	8
close to the	8
adaptive evolution of	8
its role in	8
the cas a	8
interfere with the	8
were performed in	8
the nature research	8
information about the	8
comparative analysis of	8
different bat species	8
us to identify	8
the acute phase	8
the crystal structure	8
dna was extracted	8
the likelihood of	8
functional receptor for	8
fraction of shared	8
cancer cell line	8
was obtained by	8
be infected by	8
in the kidney	8
is responsible for	8
of our study	8
of the results	8
coronavirus nonstructural protein	8
nt treatment caused	8
from the ncbi	8
samples were then	8
a lack of	8
agreement with the	8
results of the	8
enrichment connectivity diagram	8
with nsp of	8
protein from the	8
function of the	8
orf b of	8
of the d	8
and abiotic controls	8
that are under	8
measure of purifying	8
of the corresponding	8
orf b proteins	8
of human parechovirus	8
well as to	8
for the identification	8
in the viral	8
that in the	8
as defined in	8
presence of the	8
displaying pathways enriched	8
similar to that	8
supplementary file d	8
which was not	8
of nt protein	8
were unable to	8
to examine the	8
of this article	8
and or nk	8
density in the	8
world fruit bats	8
cell types in	8
single null cells	8
airway epithelial cells	8
immunoglobulin heavy chain	8
at different time	8
component of the	8
in figure d	8
risk of infection	8
hcmec d cells	8
isolation and characterization	8
phase of the	8
in the middle	8
disorder profiles of	8
course of the	8
frcs in pps	8
pond et al	8
be important for	8
pulmonary marginated neutrophils	8
a in the	8
pathway gene set	8
located at the	8
incubated for h	8
supplementary information is	8
number of shared	8
room temperature and	8
torin treated seedlings	8
in the cell	8
the results from	8
acrs from the	8
washed with pbs	8
appears to be	8
can be observed	8
specific cell types	8
were washed three	8
c for minutes	8
supporting the findings	8
connectivity diagram displaying	8
for further details	8
b cells were	8
in vips compared	8
room temperature in	8
we next examined	8
expression in the	8
pbs for min	8
been demonstrated to	8
in the two	8
of dom formulae	8
of the receptor	8
of dissolved organic	8
the ventral dg	8
the maintenance of	8
we showed that	8
were obtained by	8
regard to the	8
analysis showed that	8
with the most	8
world health organization	8
the ncbi database	8
presence of a	8
in this regard	8
in a wide	8
with each other	8
cell suspensions were	8
peripheral blood mononuclear	8
be related to	8
bind to the	8
are needed to	8
of emerging viruses	8
the biosynthesis of	8
we generated a	8
in figures a	8
set enrichment connectivity	8
the ulnar nerve	8
common ancestor of	8
samples of non	8
city and chicago	8
the slow phase	8
is shown in	8
by the wt	8
were collected and	8
coding regions of	8
gene expression data	8
onset and death	8
importance of the	8
of the disease	8
followed by a	8
i and ii	8
larp compared to	8
the column was	8
the host cells	8
for this purpose	8
their role in	8
as early as	8
performed using a	8
complete list of	8
antibody responses against	8
we calculated the	8
the cb infection	8
was collected and	8
of neutrophils in	8
with the host	8
blood mononuclear cells	8
cancer cell lines	8
of the cell	8
are important for	8
the igg responses	8
and centrifuged at	8
be the observed	8
methods section for	8
table presents the	8
by mass spectrometry	8
highly pathogenic avian	8
cov and bat	8
test p after	8
it is plausible	8
closure of the	8
quality of the	8
a novel coronavirus	8
figure a and	8
the day of	8
to the number	8
of the ntd	8
uptake in the	8
and supplementary figs	8
of orf b	8
pathways enriched among	8
was shown to	8
the form of	8
predicted to have	8
three reading frames	8
humans and other	8
of lbcas a	8
of middle east	8
diagram displaying pathways	8
elevation of the	8
case fatality risk	8
ms ms analysis	8
the pathogenesis of	8
data were analyzed	8
each bat species	8
adaptive amino acid	8
number of interactions	8
fibroblastic reticular cells	8
remains to be	8
rate of the	8
the reaction was	8
the third copy	8
we also thank	8
as a loading	8
sections were incubated	8
expression of ifitm	8
on the affected	8
a systematic review	8
were processed using	8
the immunoglobulin heavy	8
over the past	8
and vehicle treated	8
see methods section	8
did not affect	8
inhibition of the	8
an analysis of	8
was confirmed by	8
in this context	8
and from the	8
from the different	8
humane end points	8
is known to	8
samples were centrifuged	8
the top of	8
a recent study	8
the penton base	8
the potential of	8
this study is	8
syndrome coronavirus spike	8
absence of the	8
of pn ps	8
we do not	8
libraries were sequenced	8
nsp of bat	8
on day after	8
was centrifuged at	8
type i interferon	8
that the number	8
the parental siha	8
indicating that the	8
of an enabling	8
innate immune responses	8
cannot be explained	8
this may be	8
to sphere culture	8
presence or absence	8
these data suggest	8
mice infected with	8
rs in the	8
the need to	8
standard deviation of	8
of human adenovirus	8
infected mice that	8
a review of	8
the human body	8
the model was	8
the range of	8
that there are	8
cell types and	8
supplementary file b	8
gene expression in	8
we determined the	8
is required to	8
dunnett multiple comparison	8
of chifit in	8
suggested that the	8
and n proteins	8
ly g antibody	8
codon usage bias	8
the degree of	8
this work was	8
in comparison to	8
compared to as	8
of a human	8
to form a	8
in the form	8
top signaling axis	8
of amino acid	8
spinal cord injury	8
did not have	8
line with the	8
drawn from a	8
cell density in	8
digital contact tracing	8
in dsdna viruses	8
in supplementary tables	8
pn and ps	8
findings suggest that	8
are found in	8
outside of the	8
is robust to	8
determined to be	8
on the rbd	8
the human population	8
data supporting the	8
susceptibility loci for	8
a population of	8
in the protein	8
the plasma membrane	8
depending on the	8
in the development	8
of the monoclonal	8
to be at	8
of the gene	8
group of the	8
the association between	8
has been observed	8
in the inflamed	8
site of the	8
age group i	8
differential expression analysis	8
of the children	8
acute phase of	8
of the vips	8
further information on	8
the s glycoprotein	8
a loading control	8
we found a	8
that did not	8
grown in standard	7
as a receptor	7
dn ds ratios	7
the model is	7
investigated bat species	7
of bace in	7
caused by the	7
design is available	7
to track the	7
belong to the	7
of each sample	7
hafl or vsv	7
we identified a	7
innate lymphoid cells	7
estimates of a	7
of the manuscript	7
human endothelial cells	7
to test the	7
are responsible for	7
defined by rna	7
and gene expression	7
summary linked to	7
expression of chifit	7
or genes in	7
we performed an	7
online version of	7
consistent with this	7
purifying selection and	7
compared to that	7
for of the	7
parental siha cells	7
on the day	7
in the community	7
of the serpentine	7
we examined the	7
better understanding of	7
in the top	7
hours after lps	7
the cut site	7
the levels of	7
of the immune	7
with the help	7
to infection by	7
wide association study	7
were identified by	7
of the mean	7
relative to shams	7
found in all	7
of monoclonal antibodies	7
and resuspended in	7
we inferred the	7
indicate that the	7
the triphosphate moiety	7
in the nature	7
the chifit gene	7
of the bat	7
binds to the	7
the outbreak of	7
the decision to	7
was associated with	7
in clinical trials	7
for each sample	7
we compute the	7
of the sensor	7
as s increases	7
virus infection in	7
the sample was	7
were then incubated	7
of the family	7
serves as a	7
summarized in supplementary	7
d bioprinted model	7
the triceps brachii	7
to test for	7
the discovery of	7
was compared to	7
of proteins in	7
according to their	7
wu et al	7
of the e	7
transmission of sars	7
branches of the	7
shed light on	7
accompanies this paper	7
nt into the	7
for multiple test	7
listed in the	7
of cst axons	7
and standard deviation	7
replication of ndv	7
is able to	7
this is a	7
ercc l deficiency	7
in the r	7
chronic stress exposure	7
the reaction mixture	7
blast search of	7
to be important	7
treated seedlings compared	7
not in the	7
available upon request	7
were included in	7
the control group	7
lungs of cb	7
response to viruses	7
were removed from	7
with at least	7
may be the	7
extracted from the	7
from the data	7
quantification of the	7
gene families in	7
adaptation compared to	7
from the authors	7
in young children	7
nucleic acid detection	7
cvd risk locus	7
some of which	7
section for details	7
the location of	7
our results suggest	7
ilcs and or	7
cleavage activity of	7
we constructed a	7
in both cases	7
the severity of	7
for phylogenetic analysis	7
different cell types	7
in of the	7
levels before and	7
in d tetra	7
viral replication in	7
the lungs were	7
at least of	7
presents the fold	7
an overview of	7
reporting summary linked	7
the expected inconvenience	7
information on research	7
translation of top	7
performed on the	7
accumulated in the	7
nsp and nsp	7
the innate immune	7
the lung and	7
as in the	7
in figure b	7
number of days	7
ace tmprss dual	7
because of the	7
susceptible to sars	7
characterized by the	7
need to be	7
according to our	7
roles of the	7
seems to be	7
zika virus infection	7
supplementary figure c	7
purifying selection than	7
like to thank	7
removed from the	7
of cell types	7
laryngeal echolocating bats	7
the type i	7
was indicated by	7
total rna was	7
driven by the	7
the nature of	7
comparison test was	7
and analyzed by	7
were subjected to	7
to react with	7
effects of the	7
the virus and	7
may not be	7
the sequences of	7
were determined using	7
with the other	7
mice compared to	7
in the cb	7
and cloned into	7
nat commun doi	7
after a time	7
information accompanies this	7
the most potent	7
between december and	7
with more than	7
the monoclonal antibodies	7
the dorsal dg	7
the average dn	7
online at http	7
the receptor binding	7
repressed by torin	7
incubated at o	7
same clonal genotype	7
the genome assembly	7
samples with the	7
were collected from	7
of the epidemic	7
ace ctsl dual	7
replicase polyprotein ab	7
used to determine	7
of the ace	7
of immune cells	7
mean and standard	7
research design is	7
also showed that	7
using the r	7
supplementary information accompanies	7
of ifitm in	7
by a single	7
a ratio of	7
of this work	7
along the sepsis	7
data of the	7
conflict of interest	7
to the wild	7
the asymptotic mk	7
was replaced with	7
entry into the	7
and the s	7
we observed no	7
are expressed in	7
the concept of	7
of the brain	7
area under the	7
vips than in	7
a tool for	7
previously shown that	7
prefusion to postfusion	7
well as other	7
the ifitm family	7
estimated to be	7
dissolved organic carbon	7
the same clonal	7
cells were then	7
using the following	7
allows us to	7
at hours after	7
of the different	7
infected mice compared	7
added to each	7
meningococcal adhesion to	7
type of stress	7
little is known	7
increases of rv	7
and s proteins	7
provided in the	7
many of these	7
the test set	7
to be involved	7
with tgev and	7
of the crrna	7
were performed as	7
that there is	7
observation that the	7
these proteins are	7
to study the	7
and variant rnaps	7
the increase in	7
deposited in the	7
dna damage response	7
f and supplementary	7
identity with human	7
sequences of size	7
and that the	7
adaptation in the	7
we discovered that	7
than in the	7
in the pps	7
test was performed	7
of the key	7
protein in the	7
available within the	7
to the other	7
found in supplementary	7
the antibody response	7
responses in the	7
functional analysis of	7
integrated land use	7
in pulmonary marginated	7
the potential to	7
to the fact	7
has been suggested	7
prime boost vaccination	7
with a new	7
we demonstrated that	7
of d bioprinted	7
binding and entry	7
structures of the	7
was quantified using	7
most abundant common	7
to better understand	7
on research design	7
not affected by	7
is linked to	7
r d systems	7
severity of the	7
than in non	7
are presented as	7
the starting samples	7
shown that the	7
data are available	7
the control of	7
bone marrow failure	7
land tenure and	7
the quality of	7
that participate in	7
the hypothesis that	7
the virus replication	7
was employed to	7
surface plasmon resonance	7
sequences in viruses	7
adaptation in mammals	7
was assessed by	7
and after acute	7
types of stress	7
the h n	7
of the functional	7
also found that	7
a horizontal ladder	7
nature research reporting	7
positively selected sites	7
the probability of	7
leading to the	7
ch f cells	7
within the same	7
have been identified	7
was detected in	7
the deoxyribose moiety	7
mice exposed to	7
cell types that	7
the accuracy of	7
have been deposited	7
together with the	7
all samples were	7
the risk of	7
and it is	7
result showed that	7
on the one	7
more than million	7
to demonstrate the	7
bace and bace	7
to investigate whether	7
of a single	7
coding region features	7
mrna expression of	7
incorporation by the	7
sequences were identified	7
interactions between proteins	7
of the mers	7
it is known	7
the inflamed lungs	7
of the first	7
we could not	7
of the remaining	7
linked to this	7
dependent on the	7
higher rates of	7
the virus to	7
quantitative analysis of	7
attached to the	7
by the same	7
a role for	7
this study were	7
aligned to the	7
and the d	7
with the exception	7
peer review information	7
the magnitude of	7
as the gene	7
min and then	7
infection by sars	7
of genes involved	7
binding affinity to	7
the interaction of	7
by mapman analysis	7
one of these	7
calculated for each	7
compared to wild	7
represented sequences identified	7
were prepared from	7
stranded rna viruses	7
and used to	7
be needed to	7
the help of	7
robustness of the	7
in echolocating bats	7
of the covid	7
and do not	7
of nt into	7
is equal to	7
genomic diversity of	7
of cas a	7
our study provides	7
of the severe	7
some of these	7
and supplementary file	7
which is consistent	7
composition of the	7
patients in the	7
illustrated in fig	7
we developed a	7
in our case	7
the open active	7
of adaptive evolution	7
of the peptide	7
to be under	7
is known about	7
analyses of the	7
for a given	7
adaptation in a	7
of the cells	7
model of the	7
properties of the	7
difference in pn	7
species of the	7
all of which	7
falciparum circumsporozoite protein	7
the estimation of	7
a significant association	7
of facs buffer	7
stronger purifying selection	7
to be disordered	7
acts as a	7
with a maximum	7
h n influenza	7
were cloned into	7
antibody responses in	7
of the top	7
of which are	7
analysis revealed that	7
rate of adaptation	7
sars cov and	7
isg and hla	7
essential for the	7
prior to the	7
the training set	7
of ace tmprss	7
s e orchid	7
in the model	7
we would like	7
the inhibition of	7
old world fruit	7
eight weeks after	7
by comparing the	7
the spinal cord	7
of the t	7
the s and	7
the values of	7
in the tree	7
the result showed	7
difference between the	7
infection of human	7
the serial interval	7
the mean value	7
determined by mapman	7
response to infection	7
of the candidate	7
and supplementary tables	7
in energy of	7
would like to	7
class switch recombination	7
hek t cells	7
as the number	7
and for the	7
care and use	7
it is therefore	7
the performance of	7
we propose that	7
with the human	7
or nk cells	7
multiple comparison test	7
supplementary table is	7
of dom molecular	7
under the curve	7
to further investigate	7
results show that	7
of ifitm protein	7
to the cells	7
the most important	7
we reasoned that	7
variants in the	7
the spike glycoprotein	7
for shared rides	7
in the prefusion	7
in hong kong	7
is a key	7
in vivo and	7
serum samples were	7
heavy and light	7
liu et al	7
cell rna sequencing	7
was assessed using	7
in figure a	7
willingness to share	7
molecular mechanisms of	7
fruit bat and	7
different stages of	7
were enriched in	7
for zikv infection	7
cleavage of the	7
lc ms ms	7
is characterized by	7
in the binding	7
only a single	7
schematic diagram of	7
the association of	7
we carried out	7
the lungs at	7
of this protein	7
in the present	7
assumed to be	6
were supplemented with	6
linear discriminant analysis	6
these two proteins	6
a license to	6
by the severe	6
a mean ppid	6
is plausible that	6
a panel of	6
female balb c	6
the original genome	6
adjusted for multiple	6
methods and supplementary	6
represented sequences were	6
december and january	6
represented sequences of	6
influenza a h	6
models were used	6
age and sex	6
of these three	6
contribution to the	6
to display the	6
three studied coronaviruses	6
similar to those	6
immunoreactivity in the	6
flow rate of	6
that the majority	6
in a given	6
grown in the	6
used to measure	6
the consensus sequence	6
we have used	6
due to its	6
genes of the	6
led us to	6
loci for kawasaki	6
which has been	6
the ebov gp	6
that it is	6
of the overall	6
sox in cells	6
estimates of the	6
of the study	6
obtained by the	6
viruses and their	6
of the control	6
the orf a	6
it does not	6
the specificity of	6
with the observation	6
half of the	6
patterns of co	6
reduction in the	6
among the most	6
to be an	6
a handful of	6
the coding sequence	6
wang et al	6
transformed fold change	6
temperature for min	6
in a dose	6
license to display	6
detour and inconvenience	6
replicase polyprotein a	6
to reduce the	6
supplemented with mm	6
given that the	6
nsp protein is	6
coronary artery disease	6
log transformed p	6
mice were anesthetized	6
media plus mm	6
a h n	6
generated from the	6
the human interactome	6
h n viruses	6
identified as a	6
that at least	6
cervical spinal cord	6
blood was collected	6
for this reason	6
the median topscore	6
of cytosolic rp	6
the preprint in	6
is shown for	6
during the infection	6
these proteins were	6
structural proteins of	6
from the convalescent	6
a host to	6
of the interferon	6
s trimer to	6
not certified by	6
antibodies against mers	6
of the chifit	6
is the same	6
rna binding residues	6
in supplementary document	6
the in vivo	6
c and d	6
years of life	6
expression of cd	6
of the ntp	6
a list of	6
the presence or	6
variants detected in	6
tend to have	6
were cultured with	6
principal component analysis	6
sgrnas targeting pag	6
the gel panels	6
expression level of	6
protein as a	6
s and n	6
for multiple testing	6
interactions on the	6
western blot for	6
viruses in the	6
in conjunction with	6
that this is	6
competing financial interests	6
analysis reveals that	6
plus mm glucose	6
in the last	6
effect of the	6
depicts the log	6
phylogenetic analysis and	6
and development of	6
day after infection	6
the classic mk	6
cell types with	6
the little brown	6
profiled by rna	6
of viral evolution	6
changes in energy	6
bat species of	6
dynamics of the	6
as one of	6
genes from the	6
emerging infectious diseases	6
by the tor	6
copy of bace	6
in the figure	6
the maximum likelihood	6
as a potential	6
neutralizing antibodies against	6
revealed the presence	6
activity of the	6
phosphorylation of the	6
nsp is a	6
viability of cw	6
the contribution of	6
with a high	6
binding regions in	6
tor signaling network	6
to test this	6
the mammalian tree	6
coronaviruses as the	6
and frozen in	6
olfactory receptor genes	6
number of proteins	6
resulted in the	6
behavioural and biological	6
between the high	6
were no differences	6
possibility that the	6
performed as previously	6
of all the	6
tagged cas following	6
number of users	6
the circumsporozoite protein	6
in the studied	6
for each species	6
even in the	6
to predict the	6
the city center	6
to assess whether	6
it is the	6
does not contain	6
in most cases	6
inflammatory lung injury	6
in case of	6
of initial dose	6
were conducted in	6
it is noteworthy	6
for min on	6
axis depicts the	6
in the data	6
likelihood ratio tests	6
analyses were performed	6
the human ace	6
in the final	6
intrinsic disorder propensity	6
significant association of	6
balf and pbmc	6
from the corresponding	6
and human sars	6
for the protein	6
and b m	6
tecs were assembled	6
presence of dom	6
mice that had	6
attenuated in the	6
granted medrxiv a	6
hpai h n	6
adaptation to viruses	6
a graded load	6
parental siha and	6
by torin treatment	6
has granted medrxiv	6
the changes in	6
age of dementia	6
c and hadv	6
analysis of sars	6
that they have	6
required for optimal	6
rapid d bioprinting	6
the common ancestor	6
research reporting summary	6
no evidence of	6
hepatitis c virus	6
active site and	6
the interaction with	6
national capacity to	6
mean ppid of	6
log transformed fold	6
for true acrs	6
in the rna	6
upregulated in the	6
ercc l and	6
it may be	6
no differences in	6
the diversity of	6
the sampled non	6
proportions of selected	6
significant decrease in	6
were differentially expressed	6
the cause of	6
the vampire bat	6
samples were rinsed	6
a component of	6
as measured by	6
with a higher	6
statistical analyses were	6
were assessed using	6
were collected at	6
higher number of	6
found that a	6
fetal bovine serum	6
result of the	6
of the nsp	6
replication of rna	6
and control of	6
that all the	6
in specific cell	6
for all the	6
no differences between	6
the order of	6
proportion of selected	6
supplementary file a	6
mm edta in	6
analysis of large	6
has been made	6
volcano plot of	6
igm and igg	6
during the first	6
likelihood ratio test	6
in vips than	6
the species tree	6
an average of	6
the author funder	6
of the original	6
depends on the	6
important reservoir hosts	6
display the preprint	6
with technical replicates	6
derived neurotrophic factor	6
three of the	6
was not certified	6
were detected by	6
was isolated from	6
by using the	6
infected by sars	6
it is a	6
to mutational hotspots	6
in rhinolophoid bats	6
were observed in	6
repressed in larp	6
to be associated	6
except for the	6
potential of chifit	6
in the active	6
each pair of	6
in down syndrome	6
available at http	6
between onset and	6
ppids of nsp	6
a single ride	6
anesthetized with ketamine	6
while the y	6
feline immunodeficiency virus	6
of the a	6
were upregulated in	6
university of california	6
accumulated to significantly	6
in cb infection	6
the need for	6
and other mammals	6
by centrifugation at	6
signature of d	6
open active site	6
cells compared to	6
in vitro transcription	6
measure of the	6
whether or not	6
lateral flow assay	6
of genes under	6
as reservoirs of	6
function for the	6
is also a	6
epidermal growth factor	6
protein data bank	6
of n protein	6
of the entire	6
has been previously	6
an hth domain	6
microbial communities in	6
used to evaluate	6
in the ulnar	6
the corresponding author	6
top of the	6
genomic dna was	6
at rpm for	6
reported in this	6
account for the	6
by the institutional	6
edta in pbs	6
on the data	6
by the fact	6
function in the	6
the ntd of	6
is noteworthy that	6