quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram frequency
severe acute respiratory syndrome96
acute respiratory syndrome coronavirus72
rs rs rs rs61
ifitm ifitm double null36
in the presence of35
of severe acute respiratory32
was used for statistical27
in supplementary table s27
used for statistical analysis27
middle east respiratory syndrome26
the total number of26
was used as a26
on the other hand24
in the d tetra24
as well as the24
ifitm double null cells23
east respiratory syndrome coronavirus23
is consistent with the22
in the context of22
in the absence of21
the severe acute respiratory21
and supplementary table s21
chinese rufous horseshoe bat20
in the case of19
in addition to the19
a wide range of18
for each of the18
the chinese rufous horseshoe17
was performed using the17
has been shown to17
used in this study17
the egyptian fruit bat17
as shown in supplementary16
human sars and bat16
supplementary information table s16
a broad range of16
it is possible that16
authors declare no competing16
crystal structure of the16
the authors declare no16
excess of adaptation in16
been shown to be16
in the lungs of16
and bat cov are16
this study are available15
min at room temperature15
in new york city15
was added to the15
in the genomes of15
as a function of15
in vitro and in15
maps and institutional affiliations14
claims in published maps14
test was used for14
for min at room14
for h at room14
published maps and institutional14
springer nature remains neutral14
to jurisdictional claims in14
this paper at https14
vitro and in vivo14
neutral with regard to14
in published maps and14
sars and bat cov14
regard to jurisdictional claims14
the data in supplementary14
jurisdictional claims in published14
remains neutral with regard14
with regard to jurisdictional14
nature remains neutral with14
h at room temperature14
one of the most13
of adaptation in vips13
vs sphere cell culture13
is one of the13
with two independent sgrnas13
data are represented as13
at xg for minutes13
findings of this study13
data in supplementary table13
at room temperature for13
the ifitm ifitm double13
in the ifitm ifitm13
we found that the13
the pn ps ratio12
are included in the12
gscs in the d12
not included in the12
and the number of12
acute respiratory distress syndrome12
is not included in12
of the number of12
two independent sgrnas targeting12
the rest of the12
of shared ride requests12
analysis was performed using12
a link to the11
access this article is11
in any medium or11
by the presence of11
at the same time11
to the original author11
a member of the11
not permitted by statutory11
if material is not11
of the supplementary material11
directly from the copyright11
the findings of this11
your intended use is11
you will need to11
frozen in liquid nitrogen11
in standard sphere culture11
exceeds the permitted use11
indicate if changes were11
link to the creative11
if changes were made11
images or other third11
ray crystal structure of11
of the s trimer11
by statutory regulation or11
commons license and your11
and indicate if changes11
you give appropriate credit11
any medium or format11
creative commons license and11
intended use is not11
and reproduction in any11
to view a copy11
or other third party11
this article is licensed11
copy of this license11
to the creative commons11
permitted by statutory regulation11
the structure of the11
permission directly from the11
distribution and reproduction in11
gscs in sphere culture11
shown in supplementary fig11
or exceeds the permitted11
long as you give11
and your intended use11
party material in this11
from the copyright holder11
is licensed under a11
table and supplementary fig11
this article are included11
for the treatment of11
open access this article11
material in this article11
indicated otherwise in a11
under a creative commons11
will need to obtain11
as you give appropriate11
we were able to11
in a credit line11
a credit line to11
license and your intended11
of group ilcs and11
line to the material11
use is not permitted11
material is not included11
a creative commons attribution11
shown in supplementary table11
view a copy of11
a large number of11
as long as you11
appropriate credit to the11
article is licensed under11
need to obtain permission11
of the active site11
regulation or exceeds the11
table of the supplementary11
provide a link to11
of this study are11
licensed under a creative11
declare no competing interests11
unless indicated otherwise in11
credit to the original11
ifitm double null cell11
and the chinese rufous11
g for min at11
can be found in11
at the time of11
article are included in11
obtain permission directly from11
the images or other11
to obtain permission directly11
are available from the11
is not permitted by11
statutory regulation or exceeds11
in all three viruses11
other third party material11
the creative commons license11
a copy of this11
otherwise in a credit11
credit line to the11
in cb infected mice11
third party material in11
give appropriate credit to11
in this article are11
the end of the11
reproduction in any medium11
the binding of the10
at o c for10
between vips and non10
be due to the10
and supplementary figure s10
vs gscs in the10
correspondence and requests for10
vips compared to non10
nsp s from sars10
anova with dunnett multiple10
is the number of10
enabling environment for ldn10
have been shown to10
following treatment with two10
are listed in supplementary10
the dn ds ratio10
should be addressed to10
a and supplementary fig10
was observed in the10
may be due to10
and bat cov nsp10
the average number of10
gene set enrichment analysis10
treatment with two independent10
of the egyptian fruit10
provided in supplementary table10
note springer nature remains10
and ifitm ifitm double10
and characterization of a10
of human sars cov10
it is important to10
new york city and10
in the number of10
an enabling environment for10
orf a and orf10
s s s s10
in the main manuscript10
on the surface of10
and functional characterization of10
the size of the9
of the dn ds9
and requests for materials9
this is consistent with9
permission information is available9
standard sphere culture vs9
in the coding regions9
the authors declare that9
a and supplementary table9
of all three viruses9
was then added to9
the vast majority of9
mhc class i molecules9
the large flying fox9
is available for this9
each of the three9
requests for materials should9
after acute stress exposure9
an important role in9
and permission information is9
use of the affected9
the role of the9
of the affected forelimb9
bat cov nsp proteins9
structure of the sars9
for this paper at9
are predicted to be9
in the microcosms with9
for the great leaf9
for materials should be9
in a mouse model9
in accordance with the9
can be used to9
in pps and mlns9
available for this paper9
materials should be addressed9
b and supplementary fig9
were found to be9
information is available for9
igg and igm responses9
the supplementary material for9
with respect to the9
the length of the9
in the great leaf9
see supplementary information for9
reprints and permission information9
a mouse model of9
for the development of9
at the end of9
ranked in first place9
of cb infected mice9
mrna expression signature of9
at a concentration of8
are likely to be8
york city and chicago8
as shown by the8
seedlings compared to wt8
are shown in supplementary8
measure of purifying selection8
bat and the chinese8
elevation of the dn8
respiratory syndrome coronavirus spike8
centrifuged at xg for8
are provided in supplementary8
the third copy of8
vips with the same8
the fact that the8
for the identification of8
energy of the complex8
presence or absence of8
the development of the8
at different time points8
cannot be explained by8
the presence of a8
that the number of8
connectivity diagram displaying pathways8
set enrichment connectivity diagram8
data supporting the findings8
closure of the active8
a and orf b8
peripheral blood mononuclear cells8
in line with the8
were washed three times8
of an enabling environment8
play a role in8
nosed bat and the8
cells were transfected with8
in vips compared to8
as a result of8
diagram displaying pathways enriched8
in the form of8
it has been shown8
the crystal structure of8
with dunnett multiple comparison8
gene set enrichment connectivity8
the limit of detection8
the course of the8
as well as to8
for the first time8
supplementary information is available8
has been shown that8
pathway gene set enrichment8
to the number of8
o c for minutes8
in pbs for min8
the excess of adaptation8
dna was extracted from8
enrichment connectivity diagram displaying8
has been reported to8
at room temperature in8
in each of the8
permutation test p after8
displaying pathways enriched among8
was used as the8
isolation and characterization of8
nsp of bat cov8
these data are represented8
nt and vehicle treated8
as shown in fig8
highly pathogenic avian influenza8
supplementary table s and8
supplementary information for details8
of middle east respiratory8
of the p gene8
as a loading control8
supporting the findings of8
the majority of the8
see methods section for8
binding of the s7
in the development of7
of genes involved in7
information on research design7
to be involved in7
table and supplementary table7
in supplementary table is7
grown in standard sphere7
the importance of the7
integrated land use planning7
determined by mapman analysis7
random variants of the7
and after acute stress7
reporting summary linked to7
in agreement with the7
the coding regions of7
summary linked to this7
as defined by rna7
these results indicate that7
the presence of the7
infected mice compared to7
these data suggest that7
as described in the7
number of shared ride7
in complex with the7
were added to the7
to the fact that7
cell density in the7
table s and supplementary7
treated seedlings compared to7
of the sars coronavirus7
the acute phase of7
washed three times with7
available in the nature7
in the cb infection7
the online version of7
as well as other7
as determined by mapman7
old world fruit bats7
of mrnas that encode7
specific igg and igm7
of people with ds7
incubated at o c7
lungs of cb infected7
were carried out in7
infusion of nt protein7
before and after acute7
is found to be7
information accompanies this paper7
ilcs and or nk7
the elevation of the7
little is known about7
syndrome coronavirus spike protein7
the distribution of the7
from human sars cov7
our results suggest that7
of the spike protein7
the asymptotic mk test7
sequences of size m7
see supplementary table s7
in pulmonary marginated neutrophils7
difference in pn ps7
methods section for details7
supplementary information accompanies this7
with tgev and prcv7
and or nk cells7
with the help of7
for multiple test correction7
be found in the7
translation of top mrnas7
cb infected mice that7
further information on research7
is available in the7
which is consistent with7
accompanies this paper at7
comparison test was used7
linked to this article7
in the nature research7
to that of the7
in terms of the7
c and supplementary fig7
multiple comparison test was7
supplementary figure s a7
sequences that are under7
used as a loading7
is available in supplementary7
with regard to the7
in this study were7
em structure of the7
the genomes of the7
a fraction of the7
levels before and after7
sars cov and bat7
test p after iterations7
on research design is7
the analysis of the7
area under the curve7
egyptian fruit bat and7
the replication of ndv7
for each bat species7
were generated using the7
along the sepsis timeline7
eight weeks after stroke7
of the severe acute7
of dom molecular formulae7
design is available in7
group ilcs and or7
table presents the fold7
of the s subunit7
in energy of the7
research design is available7
in supplementary information fig7
in the human population7
lane profiles of transcription6
the d bioprinted model6
the rate of the6
that the majority of6
found to be highly6
were then incubated with6
with a new coronavirus6
cells were incubated at6
in the ulnar nerve6
between standard sphere culture6
has granted medrxiv a6
the log transformed fold6
on the one hand6
mm edta in pbs6
which was not certified6
of the s glycoprotein6
as well as a6
cell viability of cw6
the identification of the6
expression signature of d6
predicted to be disordered6
transformed p value adjusted6
the genes from the6
added to the cells6
parental siha and ifitm6
in the lungs at6
compared to the wild6
cov and bat cov6
way anova with tukey6
groups based on the6
for minutes at room6
the adoption of ride6
was found to be6
structure of human adenovirus6
version of this article6
the results of the6
volcano plot of transcriptional6
revealed the presence of6
the significance of the6
cells for h at6
at a flow rate6
test was used to6
samples were centrifuged at6
who has granted medrxiv6
of olfactory receptor genes6
certified by peer review6
is the author funder6
log transformed p value6
be found in supplementary6
of the monoclonal antibodies6
to be associated with6
adjusted for multiple test6
reservoir hosts of emerging6
as the gene source6
levels of the genes6
as the number of6
granted medrxiv a license6
tubulin was used as6
is available online at6
was performed as described6
it is noteworthy that6
were centrifuged at xg6
of nsp s from6
ercc l is required6
of adaptation compared to6
as one of the6
then added to the6
samples with the same6
used as a control6
would like to thank6
the most abundant common6
cells were washed three6
the preprint in perpetuity6
simple permutation test p6
for details on the6
information is available online6
was approved by the6
compared to sphere culture6
important reservoir hosts of6
was not certified by6
in the dorsal dg6
axis shows the log6
by the severe acute6
the nature research reporting6
value adjusted for multiple6
cas following treatment with6
human sars cov and6
in the supplementary materials6
variants of the viruses6
presence of dom formulae6
was indicated by the6
reuse allowed without permission6
in response to viruses6
information is available at6
the gene source of6
is in line with6
depicts the log transformed6
are represented as a6
in the regulation of6
structural basis for the6
from the different categories6
torin treated seedlings compared6
culture model as defined6
shown in supplementary information6
in vips than in6
expression of ace and6
coronaviruses as the gene6
between onset and death6
way anova with dunnett6
minutes at room temperature6
cells were treated with6
animal care and use6
source data are provided6
by the fact that6
vips than in non6
medrxiv a license to6
for new york city6
to be important for6
not certified by peer6
and frozen in liquid6
mice that had reached6
in larp compared to6
for the analysis of6
we would like to6
cb infected mice compared6
between december and january6
ercc l d n6
a complete list of6
positive cells in the6
approved by the institutional6
available online at http6
loci for kawasaki disease6
the s trimer to6
of intrinsic disorder in6
axis depicts the log6
signature of d bioprinted6
s and n proteins6
broad range of mammals6
the type of stress6
the incorporation of the6
the presence of dom6
listed in supplementary information6
available in supplementary table6
in response to torin6
the open active site6
was present in the6
see table of the6
media plus mm glucose6
study are available from6
in response to infection6
the log transformed p6
the presence or absence6
the top of the6
in a wide range6
genes from the different6
research reporting summary linked6
from a host to6
to display the preprint6
p value adjusted for6
care and use committee6
are available within the6
there were no differences6
kosakovsky pond et al6
at room temperature and6
in the d tri6
study are available within6
license to display the6
of the genes from6
no reuse allowed without6
as and cb infections6
the common ancestor of6
the active site and6
ifitm single null cells6
a host to another6
ifitm and ifitm proteins6
display the preprint in6
the little brown bat6
model as defined by6
the lungs of cb6
the classic mk test6
female balb c mice6
cells were grown in6
s and supplementary figure6
log transformed fold change6
based on the data6
cellular rna was extracted6
room temperature for min6
we were unable to6
institutional animal care and6
of ace and tmprss6
was carried out in6
of purifying selection in6
as compared to the6
the same clonal genotype6
shows the log transformed6
proportion of selected codons6
is required for optimal6
a license to display6
l is required for6
is available at http6
of d bioprinted tetra6
proportions of selected codons6
similar to that of6
mean ppids of nsp6
it is plausible that6
a flow rate of6
indicated by the presence6
rna was extracted from6
nature research reporting summary6
sections were incubated with6
closely related to the6
tagged cas following treatment6
ppids of nsp s5
whisker plot in figure5
both as and cb5
within each cell type5
first years of life5
the absence of the5
outbreak associated with a5
in response to tor5
strength ms media plus5
of the spike glycoprotein5
figure a and b5
on the mrna expression5
of probable bat origin5
a clinically proven protease5
in at least of5
infected mice that had5
can be infected by5
were assembled using the5
crystal structure of human5
rna was extracted and5
supernatant was transferred to5
is a functional receptor5
are the number of5
were identified in the5
ncov spike in the5
activity is required for5
characterization of a bat5
predicted by morfchibi web5
under the control of5
translationally repressed by torin5
endo conformation of the5
requests for shared rides5
to the peer review5
cell entry depends on5
the likelihood function for5
buffer containing mm tris5
luciferase expressing gscs in5
to be at risk5
in the ventral dg5
in the pathogenesis of5
have previously shown that5
with tukey multiple comparison5
patients were grouped into5
of dissolved organic matter5
viability of cw luciferase5
function for the data5
on ace and tmprss5
at the mean value5
total number of requests5
holder for this this5
are expressed in the5
the immunoglobulin heavy chain5
age of dementia onset5
a functional receptor for5
using the r package5
frcs in pps and5
phylogenetic analysis by maximum5
due to the high5
at the protein level5
to interact with the5
numbers of dom molecular5
declare no competing financial5
lysis buffer containing mm5
centered at the mean5
material for further details5
were calculated using the5
the quality of the5
our closest living relatives5
was added to each5
in close proximity to5
known acrs from the5
had reached humane end5
pathways enriched among functional5
in the inflamed lungs5
the initial positive set5
reached humane end points5
of human sars nsp5
at rpm for min5
error bars represent standard5
the difference in pn5
cells were cultured with5
is involved in the5
error bars represent the5
but not in the5
samples from the same5
of the evolution of5
tmprss and is blocked5
between the two groups5
represented sequences identified in5
a central role in5
the university of california5
be infected by sars5
protein of severe acute5
are centered at the5
there is an increasing5
was extracted and purified5
tables s and s5
that uses the ace5
the replication of rna5
the fraction of shared5
in the energy of5
summarized in supplementary table5
the genome sequences of5
among functional dependency genes5
like coronavirus that uses5
were detected in the5
of neisseria meningitidis to5
in the prefusion conformation5
resuspended in ml of5
it is known that5
humans and other mammals5
n a l p5
or low signature expression5
in line with this5
hosts of emerging viruses5
the expression of other5
coronavirus of probable bat5
both ace and tmprss5
of human sars and5
was transferred to a5
functional receptor for the5
new coronavirus of probable5
pneumonia outbreak associated with5
of these genes were5
id g in the5
culture vs gscs in5
influenza a h n5
host genomic diversity of5
the results from the5
slope of log expression5
landscape profiled by rna5
copyright holder for this5
the genome of the5
in vips and non5
for min at rt5
are available in the5
likelihood function for the5
in as or cb5
by a clinically proven5
for phylogenetic analysis and5
of egyptian fruit bat5
ace and tmprss are5
compared to as infected5
smoking status associations with5
a new coronavirus of5
occurrence of minor variants5
in the colombian study5
of transcriptional landscape profiled5
changes in the energy5
due to the fact5
to further understand the5
attenuated in the ifitm5
analysis by maximum likelihood5
mean value and error5
siha and ifitm ifitm5
these findings suggest that5
to as infected mice5
entry depends on ace5
the biosynthesis of asgs5
the energy of the5
plot indicates the lower5
review of this work5
as calculated by the5
for their contribution to5
in an effort to5
plot of transcriptional landscape5
values were calculated by5
similar to those of5
cko mice than in5
from the active site5
the reaction mixture was5
we observed that the5
p r o o5
due to mutational hotspots5
associated with a new5
depends on ace and5
the pcr products were5
these data indicate that5
microcosms with high salinity5
blocked by a clinically5
a false discovery rate5
available from the corresponding5
and vehicle treated rats5
we also found that5
it has been reported5
peer review of this5
pellets were resuspended in5
a pneumonia outbreak associated5
and their role in5
grouped into high or5
coronavirus that uses the5
room temperature for minutes5
all three reading frames5
macrophages in the d5
our data suggest that5
with nsp of bat5
are one of the5
by severe acute respiratory5
may be related to5
and the d tetra5
play an important role5
high or low signature5
in human sars cov5
the neutralizing activity of5
this this version posted5
blocked with bsa in5
the number of shared5
human tumor cell lines5
is based on a5
most abundant common under5
the protein sequences of5
expression groups based on5
used as the biocatalyst5
sequences were identified in5
for the data in5
single cell suspensions were5
for min on ice5
also referred to as5
materials and methods and5
available from the authors5
cells were incubated with5
was supported by the5
available at this link5
supplementary material for further5
spike in the prefusion5
a derived allele frequency5
the double ifitm ifitm5
clinically proven protease inhibitor5
to infection by sars5
bsa in pbs for5
respiratory syndrome coronavirus protein5
ml of facs buffer5
are found to be5
as a measure of5
r o o f5
of a bat sars5
were grouped into high5
susceptibility loci for kawasaki5
neutrophils in inflamed lungs5
reservoirs of the virus5
in age group i5
acrs from the initial5
p values were calculated5
characterization of a novel5
for this this version5
in this study are5
we assume that the5
this version posted september5
low signature expression groups5
on the treated side5
was then removed and5
value and error bars5
number of users s5
the use of the5
we have previously shown5
a l p r5
of respondents indicated that5
the copyright holder for5
and tmprss and is5
contribution to the peer5
at least one member5
medium was added to5
at different stages of5
in the active site5
it is the only5
the extent to which5
indicates the lower quartile5
positive ace tmprss cells5
a single dose of5
ace and tmprss and5
larp compared to wild5
on day after infection5
on the day of5
on the cell surface5
receptor for the sars5
the expression levels of5
tukey multiple comparison test5
in the online version5
fraction of rides shared5
analysis of gene expression5
and cb infected mice5
from the convalescent group5
data were analyzed using5
and standard deviation of5
that had reached humane5
stimulation of the affected5
plays an important role5
the difference in the5
listed in supplementary table5
based on the median5
mice were anesthetized with5
with the exception of5
tool for phylogenetic analysis5
of positive selection in5
of mhc class i5
enriched among functional dependency5
no competing financial interests5
bars are centered at5
the result showed that5
both ifitm and ifitm5
the age distribution of5
between the number of5
were calculated by the5
is blocked by a5
bars represent standard deviation5
required for optimal csr5
the computation of the5
on the use of5
in a variety of5
igg and igm profile5
the receptor binding domain5
binding domain of the5
anova with tukey multiple5
from the initial positive5
protein from human sars5
at later time points5
repressed by torin treatment5
at least of the5
j o u r5
and is blocked by5
were upregulated in the5
their contribution to the5
the world health organization5
was performed using a5
adaptive amino acid changes5
signature expression groups based5
and smoking status associations5
identity with human sars5
will be needed to5
has been observed in5
grown in the d5
based on the mrna5
represented as a box5
a similar number of5
r n a l5
protein of human sars5
better understanding of the5
the peer review of5
l p r e5
uses the ace receptor5
and error bars represent5
o u r n5
in the human lineage5
into high or low5
the mean value and5
represented sequences in the5
at a resolution of5
the sequence of the5
a better understanding of5
sphere culture vs gscs5
during the course of5
the characterization of the5
ms media plus mm5
u r n a5
data suggest that the5
transcriptional landscape profiled by5
were obtained from the5
a tool for phylogenetic5
whisker plot indicates the5
all three studied coronaviruses5
the expression of ace5
d n d s5
mean and standard deviation5
at a graded load4
accumulation of clonal variants4
dna binding residues in4
the case of the4
provided the full information4
orf b of sars4
as described for the4
transition of the s4
comprehensive framework for the4
the mean of the4
neutrophils in the lungs4
no difference in the4
are among the most4
represented sequences in viruses4
authors declare that they4
progress has been made4
e or ch id4
the lung and airways4
the most abundant under4
be involved in the4
of differentially expressed genes4
statistical analyses for the4
were considered to be4
the three chronic stress4
requesting a shared ride4
a given cell type4
wt torin treated seedlings4
seven human tumor cell4
host range of sars4
is known to be4
by torin treatment in4
that support the findings4
we show that the4
of amino acids contributing4
or a combination of4
multiple comparison testing was4
cloned into the lenticrisprv4
performed in accordance with4
for each of these4
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receptor regulation of apoptosis4
of the viral genome4
length of the protein4
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the expression signature score4
with a wald test4
socially isolated mice had4
regulated by the tor4
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calculated using deseq with4
benjamini and hochberg correction4
values were calculated using4
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hydrophobic interactions between proteins4
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type and variant rnaps4
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x cells per ml4
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peer review information nature4
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environmental science and policy4
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to further investigate the4
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in the analysis of4
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were calculated using deseq4
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strong signals of adaptation4
number of or genes4
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of all three studied4
presence of slightly deleterious4
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dunnett multiple comparison testing4
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specificity for inflamed lungs4
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deseq with a wald4
successively replaced each other4
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amino acid sequences of4
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were performed in accordance4
panels and chased with4
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the fast and slow4
different types of stress4
reactions were incubated at4
a humanized mouse model4
post hoc p value4
the production of il4
comparative analysis of bat4
single cell rna sequencing4
anesthetized with ketamine xylazine4
was measured using imagej4
the data supporting the4
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at risk of infection4
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pelleted at xg for4
all of the sensor4
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pn ps between vips4
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total rna was extracted4
independent sgrnas targeting pag4
the presence of slightly4
separately in each of4
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throughout the sepsis timeline4
and methods and supplementary4
we discovered that the4
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previous works have documented4
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to significantly different levels4
supplementary tables s and4
the probability density function4
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kawasaki disease genetics consortium4
methods and supplementary file4
studies have shown that4
and supplementary information fig4
testing was used for4
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energy of the s4
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we did not observe4
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orf a proteins of4
compare vips and non4
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with technical replicates each4
be explained by the4
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status associations with expression4
analysis revealed that the4
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that supramolecular organization of4
are summarized in supplementary4
respiratory syndrome coronavirus nonstructural4
our analysis reveals that4
provides insight into the4
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on ice for min4
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supernatant was collected and4
in the ncbi database4
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using deseq with a4
members of the c4
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for a subset of4
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african and asian monkeys4
a result of the4
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reviewer reports are available4
in the methods section4
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of the c cluster4
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respiratory syndrome coronavirus in4
adult and elderly rats4
was performed in the4
compared with that of4
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national institutes of health4
the evolution of flight4
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after spinal cord injury4
in the injured lungs4
primary glioblastoma surgical resection4
genes under positive selection4
performed as previously described4
it has been suggested4
we reasoned that the4
the igg responses against4
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in the domestic cat4
are given in supplementary4
we also showed that4
by morfchibi web server4
are predicted to have4
review information nature communications4
proteins of all three4
tend to interact with4
dot indicates one serum4
was used to determine4
to be required for4
sphere culture vs macrophages4
performed as described previously4
survival analysis of glioblastoma4
with the same clonal4
contains an hth domain4
provided in the supplementary4
for the sars coronavirus4
were collected and frozen4
for the maintenance of4
a steroidal glycosyltransferase ossgt4
the potential to be4
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were cloned into the4
infection of pseudotyped mers4
probability of activation of4
dependency genes that are4
for land degradation neutrality4
the number of infected4
work was supported by4
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the sum of the4
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in larp mutants compared4
the amino acid sequences4
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expression of representative genes4
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percentage of amino acids3
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selection against short nucleotide3
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the time taken to3
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to better understand the3
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protein of all three3
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the central nervous system3
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translocation along the dna3
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method for detecting positive3
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susceptibility of the recipient3
inverse correlation between ifitm3
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demonstrate that ercc l3
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the expected detour and3
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the supernatant was then3
the evolutionary history of3
data that support the3
functional receptor for sars3
provides new insights into3
references are available in3
in the supplementary table3
play important roles in3
the city of chicago3
diseases and function analysis3
the context of the3
low dimensional embedding random3
the median topscore for3
of ifitm protein in3
a population of million3
to the cells to3
and mhc class i3
in the immune response3
vips in the human3
in order to test3
excess resulted in dbco3
via neural network algorithm3
our data indicate that3
supports bat coronaviruses as3
selection at the molecular3
with the components of3
the expression of the3
cell morphology in the3
the institutional review board3
from people with ds3
a host and a3
conformational change of the3
of the immune response3
hpai h n virus3
of the virus and3
the arms race with3
included in the analysis3
set based on the3
data comparing the d3
into d bioprinted models3
at each time point3
number of high frequency3
that are associated with3
branches leading to echolocating3
maintenance of group ilcs3
of human neutralizing antibodies3
as defined in f3
inversely proportional to the3
performed separately in each3
into the lenticrisprv plasmid3
and ace pcsk at3
error bars showing standard3
unprotected sgs in the3
models were used to3
we do not have3
was used to identify3
molecular phylogeny for bats3
land tenure and access3
little brown bat and3
of the total number3
we propose that the3
were normalized using max3
for the majority of3
related coronavirus from malayan3
of neutrophils were intravascular3
into a shared ride3
the corresponding author upon3
subfamilies seven and eight3
genome of the egyptian3
in vero e cells3
are located within the3
have been associated with3
bace signal showed a3
the prevalence of infection3
in virus adaptive evolution3
iba cells in the3
the composition of the3
responsible for receptor binding3
in the protein data3
provided as a source3
alphacoronavirus adaptation and evolution3
bars indicate standard deviation3
number of hhblits hits3
single sample gene set3
step process is characterized3
results from the tsp3
in the t c3
median topscore for all3
purifying selection being equal3
il r and il3
we also show that3
in understanding sars pathogenesis3
of the immune system3
coronavirus associated with human3
dom formulae only in3
of emerging viruses capable3
in a ratio of3
host factor for zikv3
only a small proportion3
coding region of the3
the association of the3
culture signature as defined3
rpm at room temperature3
is also notable that3
in supplementary files s3
analysis was performed by3
highly susceptible to sars3
normalised bace signal showed3
important source of emerging3
at the inner face3
the potential of the3
the minor product was3
we next sought to3
was transferred to the3
seven novel mammalian and3
of each family was3
viability of gscs in3
were used as a3
were immunized by repeated3
derived primary cultured cells3
the average request rate3
identity with bat cov3
a single ifit gene3
experiments were conducted in3
proteins involved in translation3
to the impact of3
epitopes and mechanisms of3
for the intrinsic disorder3
we believe that the3
of an rna virus3
at mm mg concentration3
a binding site for3
are marked along the3
axis and scaled along3
were positively correlated with3
the gel panels and3
for hour at room3
dom formulae in both3
the affected or less3
thereby significantly streamlining the3
on the liposome surface3
article can be found3
the function of the3
that infusion of nt3
adoption in new york3
proximal to the cleavage3
acyl groups into the3
animals in each group3
in the ventral dentate3
il levels before and3
blast search of the3
control wells were supplemented3
a higher number of3
severity of the disease3
using primers mentioned in3
min and then cellular3
the amplified pcr products3
defines a case as3
be made available upon3
right edge of the3
bat virome analysis conducted3
support the findings of3
maximum weight matching problem3
against lethal challenge with3
number of requests for3
were fixed with paraformaldehyde3
all of which are3
the avirulent as strain3
and a corresponding virus3
genes upstream and downstream3
a diverse range of3
the differences in the3
moderated estimation of fold3
may have role in3
of requests for shared3
deionized and filtered water3
the early phase of3
those in the bottom3
which are expressed in3
to calculate the relative3
in the proflex pcr3
a sequence identity of3
in table of the3
lateral flow assay detecting3
of the human lung3
and c show that3
when compared with the3
we set out to3
gene source of gammacoronavirus3
in the triceps brachii3
density in the ventral3
branches of the tree3
analyzed using flowjo software3
catalytic activity is required3
in the limit of3
cell pellets were resuspended3
figure d represents the3
rigidity of our fabric3
lateral support during rearing3
ercc l and xlf3
of the conserved arg3
a review of the3
that the expression of3
of each sample was3
technical replicates and error3
rec drawn from a3
a set of proteins3
larp is required to3
the likelihood function associated3
mrna levels of the3
compared to immune non3
replication of the virus3
from charles river laboratories3
by the wt rnap3
respiratory syndrome coronavirus infection3
size of local neighborhood3
we compute the average3
high accuracy and high3
proteins were analyzed by3
prior to incubation for3
the authors upon request3
a schematic diagram of3
susceptibility to kawasaki disease3
was assessed using a3
comparing gscs in sphere3
was added into the3
could be found in3
flow cytometry using a3
catalyzed regioselective acylations of3
we further analyzed the3
the start of the3
class i viral fusion3
their role in virus3
a lethal dose of3
regulate the expression of3
online version of the3
see methods for further3
both peripheral and brain3
nsp of human sars3
the template dna strand3
controlled human malaria infection3
change in energy of3
system with sphere cell3
using a wide range3
of infected red blood3
suspensions were prepared from3
at rpm at room3
three times with cold3
homologs were found in3
side of the body3
both in vitro and3
cvd risk locus in3
deltacoronavirus supports bat coronaviruses3
caused by the novel3
forelimb for lateral support3
with symptoms and medication3
edge of the gel3
of the virus to3
lead cvd risk snps3
it is obvious that3
bats are natural reservoirs3
has been suggested to3
for securing land tenure3
arms race with viruses3
steroidal glycosyltransferase ossgt from3
of iba cells in3
incubation for h at3
food and water ad3
reprints and permissions information3
used as a reference3
long constant frequency echolocation3
significantly streamlining the synthetic3
were used to generate3
from the authors upon3
such as influenza a3
along the right edge3
incubated at rt for3
securing land tenure and3
c mice were im3
with identical clonal genotype3
gene source of alphacoronavirus3
and cloned into the3
synonymous and synonymous variants3
it can be observed3
injection of irradiated pfspz3
cells to initiate zikv3
of pile and pilv3
identification of human neutralizing3
to characterize and visualize3
of the penton base3
were transferred to a3
right below the sternum3
and then transferred to3
mammalian target of rapamycin3
or arginine at position3
viruses capable of infecting3
compared to the wt3
in human sars and3
acute phase of infection3
residues in nsp of3
the number of intact3
closely related to human3
and o c ratios3
supplementary data are available3
the impact of the3
to infect vero cells3
expressed in at least3
between megabats and microbats3
human neutralizing antibodies against3
proteins that are encoded3
nsp protein of sars3
different stages of the3
in the leader of3
elimination of the third3
wt and variant rnaps3
associations with an fdr3
olfactory receptor genes linked3
source of emerging viruses3
of all hydroxyl groups3
in dbco per igg3
permissions information is available3
dsdna viruses that infect3
excess is shown for3
of a novel coronavirus3