bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
amino acid	347
cleavage sites	218
frad sites	206
binding sites	201
cleavage site	187
binding site	161
active site	159
amino acids	158
positive selection	130
sialic acid	125
secondary structure	96
crystal structure	94
local structures	85
protein structure	83
av software	83
web pages	79
fake av	76
respiratory syndrome	75
spike protein	68
protein interactions	68
mdi spacer	64
cut sites	63
molecular dynamics	63
ligand binding	62
proteolytic sites	62
conformational changes	61
secondary site	58
positively selected	55
influenza virus	54
domain names	52
wild type	52
mass spectrometry	51
host cell	51
land use	51
binding domain	50
serine protease	50
intrinsically disordered	49
acute respiratory	49
severe acute	48
protein function	48
cord uid	48
previous studies	48
doc id	48
crystal structures	47
health care	46
syndrome coronavirus	46
site loop	46
protein structures	46
mdi spacers	45
frameshift sites	45
small molecule	44
escherichia coli	44
acid sequence	43
results show	43
multiple sequence	43
present study	43
functional sites	42
cut site	42
cyber threats	42
acid residues	42
ribosomal frameshifting	41
acid sites	40
reading frame	40
serine proteases	40
results suggest	40
fusion protein	39
protein folding	39
substrate specificity	39
sequence alignment	39
terminal domain	38
protein interaction	38
per site	38
neural network	37
binding affinity	36
primary site	36
canonical cleavage	36
membrane protein	35
md simulations	35
selected sites	35
adaptive evolution	34
small island	34
protein families	34
cl pro	34
free energy	34
sox cut	33
cover per	33
highly conserved	33
circular dichroism	33
cell surface	32
glycosylation sites	32
receptor binding	32
proteolytic processing	32
gene expression	32
hydrogen bonds	32
protein surface	31
active sites	31
cell entry	31
rna polymerase	31
species richness	30
conformational change	30
transcription factors	30
mg ml	29
molecular weight	29
enzymatic activity	29
shift site	29
data set	29
nmr spectroscopy	29
middle east	29
tourism development	29
search results	29
binding proteins	28
east respiratory	28
sv cp	28
small molecules	28
bat species	28
functionally important	28
structure prediction	28
like proteinase	27
site frequency	27
immune response	27
protein complexes	27
proteolytic site	27
acid binding	27
infectious bronchitis	27
two different	27
membrane proteins	27
structural basis	27
selective pressure	27
novel coronavirus	27
sox cleavage	27
protease inhibitors	26
tourism growth	26
pc cleavage	26
coronavirus spike	26
immunodeficiency virus	26
also found	25
protein binding	25
important role	25
binding protein	25
community well	25
large number	25
cell lines	25
top end	25
protease activity	25
species diversity	25
life cycle	24
saccharomyces cerevisiae	24
proprotein convertases	24
previously described	24
also known	24
signal transduction	24
bronchitis virus	24
sequence similarity	24
case study	24
results indicate	24
viral pathogens	24
purifying selection	24
protein sequences	24
sars coronavirus	24
may also	24
directed mutagenesis	23
ebola virus	23
rna binding	23
confidence level	23
surface coverage	23
healthcare facilities	23
dynamics simulations	23
viral genome	23
cell death	23
protein sequence	23
viral proteins	23
phylogenetic tree	23
rna editing	23
human coronavirus	22
spacer use	22
protein functions	22
nucleic acid	22
genetic diversity	22
sialic acids	22
structural biology	22
recombinant protein	22
terminal region	22
data collection	22
dengue virus	22
molecular evolution	22
even though	22
high affinity	22
target proteins	22
group species	22
coverage ratio	22
protein synthesis	22
allosteric sites	22
total number	22
growth factor	22
amyloid fibrils	22
sequence information	21
molecular biology	21
immune system	21
clpro cleavage	21
phylogenetic analysis	21
rna viruses	21
computational methods	21
human cells	21
protein degradation	21
catalytic activity	21
structural information	21
traditional management	21
natural selection	21
web server	21
pp ab	21
distribution sites	21
transcription factor	21
cell culture	21
cellular processes	21
cell line	21
drug design	20
acid sequences	20
recombinant proteins	20
maximum likelihood	20
structural data	20
force field	20
key role	20
international tourism	20
phylogenetic trees	20
total cover	20
breast cancer	20
isothermal titration	20
ray crystallography	20
pol zn	20
cov clpro	20
structural studies	20
suitable sites	20
host plant	20
association rates	20
catalytic efficiency	20
membrane fusion	20
titration calorimetry	20
cell cycle	20
open reading	20
like protease	19
full length	19
structural motifs	19
infectious diseases	19
wide range	19
van der	19
human immunodeficiency	19
immune responses	19
structural features	19
search queries	19
enzyme activity	19
cancer cells	19
thermal stability	19
protein interfaces	19
structural changes	19
software distribution	19
first step	19
species composition	19
hay meadows	19
signal peptide	19
supplementary table	19
structural proteins	19
dissociation constants	19
widely used	19
glycosylation site	19
exclusion chromatography	19
supplementary data	19
naturally occurring	19
removal information	19
drug discovery	19
substrate binding	19
size exclusion	18
glycan conformations	18
target sites	18
determine whether	18
public health	18
viral replication	18
magnetic resonance	18
main protease	18
transmissible gastroenteritis	18
data analysis	18
two sites	18
adopting sites	18
sites using	18
envelope glycoprotein	18
dimensional structure	18
antisense oligonucleotides	18
sites may	18
two proteins	18
viral rna	18
electron microscopy	18
healthcare accessibility	17
ribosomal protein	17
important residues	17
stop codon	17
recent studies	17
nervous system	17
poorly understood	17
living cells	17
primary binding	17
overlapping regions	17
performed using	17
protein engineering	17
new host	17
gel electrophoresis	17
side chains	17
protein design	17
closely related	17
false positives	17
cleavage products	17
cells expressing	17
local structure	17
sites identified	17
avian influenza	17
target cells	17
travel time	17
highly pathogenic	17
target protein	17
davis thompson	17
viral community	17
dimer interface	17
mammalian cells	17
type i	17
genome sequence	17
infected cells	17
site model	17
oxidative stress	17
complex formation	17
catchment area	17
sequence analysis	17
side chain	17
structural analysis	17
nuclear magnetic	17
biological processes	16
protein complex	16
island tourism	16
test attempts	16
taken together	16
putative cleavage	16
colautti macisaac	16
log likelihood	16
electrostatic interactions	16
neurodegenerative diseases	16
results demonstrate	16
catalytic domain	16
structural characterization	16
conserved among	16
study area	16
data sets	16
diversifying selection	16
converting enzyme	16
envelope protein	16
supplementary material	16
variable sites	16
affinity chromatography	16
predicted cleavage	16
vaccine development	16
frameshift site	16
acid composition	16
clinical trials	16
results showed	16
capsid protein	16
interaction sites	15
dissociation constant	15
sequence data	15
drug development	15
caribbean tourism	15
glycan shield	15
molecular basis	15
informative sites	15
first time	15
coding sequences	15
protein aggregation	15
wide variety	15
high throughput	15
site trna	15
dn ds	15
model system	15
tree cover	15
overlapping region	15
proprotein convertase	15
association rate	15
virus infection	15
fluorescent protein	15
murine coronavirus	15
human ace	15
read counts	15
high levels	15
molecular level	15
web page	15
based methods	15
phage display	15
protein family	15
south africa	14
recombinant mbp	14
cell wall	14
positively charged	14
hydrophobic interactions	14
binding affinities	14
also observed	14
current change	14
di max	14
endoplasmic reticulum	14
new coronavirus	14
enzyme active	14
repeat proteins	14
least one	14
data bank	14
main river	14
metal ions	14
light scattering	14
reference laboratory	14
virus type	14
cluster analysis	14
virus hemagglutinin	14
transmembrane domain	14
programmed frameshifting	14
caribbean sites	14
previous work	14
present work	14
social media	14
biologically active	14
energy transfer	14
catalytic residues	14
ng ml	14
potential cleavage	14
environmental variables	14
type protein	14
political economic	14
hay meadow	14
kinetic parameters	14
metal binding	14
substitution rates	14
site binding	14
binding domains	14
surface area	14
coding region	14
inclusive development	14
previously reported	14
medical college	14
mine site	14
disordered proteins	14
structural similarity	14
codon substitution	14
tertiary structure	14
charged residues	13
murshidabad district	13
early adopter	13
economic growth	13
influenza neuraminidase	13
experimental data	13
protein data	13
fibril formation	13
time pcr	13
plant species	13
amyloid formation	13
sox targeting	13
barrow burn	13
rational design	13
health service	13
functional importance	13
sequence alignments	13
zika virus	13
relative abundance	13
recent years	13
test whether	13
protease inhibitor	13
study sites	13
cell types	13
host shutoff	13
acid substitutions	13
specific peaks	13
pdb id	13
translational modification	13
ray scattering	13
using nmr	13
coronavirus infectious	13
two decades	13
two domains	13
negatively charged	13
fusion peptide	13
proteinase cleavage	13
furin cleavage	13
molecular mechanisms	13
rna pseudoknot	13
results obtained	13
sequence identity	13
frequency per	13
like proteases	13
structure alignment	13
host cells	13
cell receptor	13
molecular mass	13
evolutionary history	13
cell membrane	13
control samples	13
transition transversion	13
gastroenteritis virus	13
kcal mol	13
physicochemical properties	13
kcat km	13
see table	13
human brain	13
central nervous	12
eukaryotic cells	12
mm tris	12
ray crystal	12
ubiquitin ligases	12
population density	12
dna binding	12
dna sequences	12
viral fusion	12
proteinase inhibitors	12
drug resistance	12
frameshifting efficiency	12
site asn	12
dry ridge	12
three different	12
remains unclear	12
tourism specialization	12
per transect	12
two binding	12
hydrogen bond	12
surface plasmon	12
single amino	12
allowed us	12
related viruses	12
free energies	12
hot spots	12
short peptide	12
site suitability	12
human genome	12
based prediction	12
fusion proteins	12
type ii	12
lake basin	12
electron density	12
spatial accessibility	12
least two	12
reading frames	12
cacybp sip	12
calcium ions	12
rna virus	12
small number	12
zn site	12
plasmon resonance	12
proteolytic enzymes	12
meade river	12
nt surrounding	12
ribosomal subunit	12
protein local	12
sequences surrounding	12
monoclonal antibodies	12
tourism industry	12
stranded rna	12
icu rotation	12
statistically significant	12
may contribute	12
creative commons	12
light chain	12
molecular mechanism	12
protease cleavage	12
darwinian selection	12
like cleavage	12
antisense oligonucleotide	12
ratio test	12
fragment screening	11
envelope glycoproteins	11
site prediction	11
throughput sequencing	11
der waals	11
pneumonia etiology	11
dependent manner	11
significant difference	11
new insights	11
native state	11
inclusive tourism	11
binding pocket	11
nsp nsp	11
pathogen interactions	11
take place	11
authors declare	11
using computational	11
ca binding	11
adoption process	11
using two	11
helix bundle	11
biochemical assays	11
two methods	11
synthetic peptide	11
methods used	11
suitable site	11
multiplicative factor	11
success rate	11
column buffer	11
terminal loop	11
united states	11
frameshift efficiency	11
proteolytic cleavage	11
dependent rna	11
hepatitis virus	11
software families	11
virus envelope	11
inaccessible areas	11
xxy yyz	11
tourism policies	11
district medical	11
em structure	11
likelihood ratio	11
linked glycosylation	11
antiviral activity	11
rich domains	11
random walk	11
tourism demand	11
analyzed using	11
binding energy	11
plot sizes	11
proteins involved	11
large subunit	11
virus replication	11
correction factor	11
drug sites	11
high degree	11
trachea tissue	11
new health	11
i will	11
dna damage	11
frame decoding	11
family members	11
building blocks	11
algan gan	11
per quadrat	11
catalytic triad	11
results provide	11
significantly different	11
bat assemblages	11
protein dynamics	11
will provide	11
support vector	11
significant differences	11
protein interface	11
disorder propensity	11
evolutionary analysis	11
furin correction	11
western norway	11
side effects	11
secondary binding	11
like receptors	11
qpcr rt	11
red queen	11
coronavirus disease	11
single protein	11
firefly luciferase	11
adaptive events	11
induced sputum	11
condition iv	11
cysteine proteases	11
therapeutic target	11
acid changes	11
spike glycoprotein	11
shed light	11
high resolution	11
enveloped viruses	10
species may	10
serine proteinase	10
ns protease	10
nucleic acids	10
prediction method	10
conserved across	10
laboratory tests	10
broadly neutralizing	10
avian na	10
better understand	10
terminal sequence	10
surface waters	10
new healthcare	10
climate change	10
study using	10
reactive oxygen	10
interacting proteins	10
native structure	10
viral diversity	10
function prediction	10
galectin fold	10
data suggest	10
dimensional structures	10
sustainable development	10
cellular functions	10
described previously	10
terminal amino	10
dual luciferase	10
low temperatures	10
domain swapping	10
species number	10
extracellular matrix	10
binding mechanism	10
connectin titin	10
lc ms	10
two protein	10
high level	10
gracilaria chilensis	10
site codon	10
healthcare service	10
two distinct	10
inhibitory activity	10
messenger rna	10
sequence motifs	10
close proximity	10
molecular recognition	10
pc inhibitors	10
predict protein	10
signaling pathways	10
hela cells	10
protein association	10
sites within	10
acid species	10
ionic strength	10
similar results	10
molecule inhibitors	10
search engines	10
information system	10
site models	10
species assemblages	10
drug binding	10
neural networks	10
many different	10
security vendors	10
selected amino	10
usage bias	10
computational design	10
structural genomics	10
viral entry	10
maximum descent	10
protein kinases	10
frameshift signal	10
data obtained	10
time point	10
posterior probability	10
statistical analysis	10
predicted sites	10
oxygen species	10
decision making	10
disulfide bonds	10
past decade	10
high accuracy	10
influenza viruses	10
primate species	10
room temperature	10
better understanding	10
drug targets	10
antigen concentration	10
crucial role	10
several studies	10
antigen sites	10
local regions	10
annual rainfall	10
enteric viruses	10
large scale	10
cleavage sequences	10
parkland areas	10
protein targets	10
virus glycoprotein	10
bovine serum	10
adenosine methylation	10
river alwin	10
ornithine decarboxylase	10
cell epitopes	10
furin inhibitors	10
rank correlation	10
capsid proteins	10
trna binding	10
catalytic site	10
findings suggest	10
also used	10
may represent	10
incoming traffic	10
structural disorder	10
neu ac	10
monte carlo	10
pro proteinase	10
machine learning	10
material online	10
resonance energy	10
great apes	10
transition state	10
serum albumin	9
surface proteins	9
binding specificity	9
viral targets	9
disordered protein	9
host immune	9
tertiary structures	9
point mutations	9
molecular docking	9
chemical shift	9
analysis showed	9
stem cells	9
ensemble modeling	9
statistical data	9
supplementary file	9
may lead	9
detecting positive	9
virtual screening	9
noncoding rnas	9
prostate cancer	9
outer membrane	9
protein expression	9
energy consumption	9
predicting protein	9
significant changes	9
substitution models	9
target cell	9
allows us	9
medical institution	9
simian immunodeficiency	9
pseudo amino	9
ion channels	9
hydrogen bonding	9
molecular adaptation	9
studies revealed	9
pichia pastoris	9
phosphorylation sites	9
disordered regions	9
reach frad	9
sites predicted	9
false positive	9
tourism intensity	9
receptor recognition	9
secondary structures	9
user accesses	9
graduate school	9
native protein	9
frameshift signals	9
viral metagenomics	9
nonhuman primates	9
additional species	9
world health	9
protein production	9
functional relationships	9
sequence motif	9
mrna levels	9
arms race	9
viral particles	9
ancestral sequences	9
glyc site	9
differential scanning	9
analysis revealed	9
making approach	9
targeting element	9
positive darwinian	9
structure similarity	9
bat coronavirus	9
suitability analysis	9
relationships among	9
positive set	9
drug target	9
accessibility index	9
crystal form	9
repeat protein	9
land cover	9
dipeptidyl peptidase	9
common species	9
health services	9
sites located	9
secretory pathway	9
biological sciences	9
hybrid decision	9
practice change	9
western australia	9
provide insight	9
highly specific	9
functional analysis	9
distantly related	9
virus populations	9
protein surfaces	9
binding partners	9
human coronaviruses	9
protein products	9
euclidean distance	9
tourism market	9
analytical ultracentrifugation	9
partially folded	9
nsp protein	9
valuable information	9
novel human	9
site occupancy	9
small angle	9
mouse hepatitis	9
data available	9
peptide substrates	9
past two	9
bottom fauna	9
site residues	9
disulfide bond	9
resolution structure	9
stop codons	9
protein docking	9
san diego	9
may play	9
measured using	9
area curves	9
abundant species	9
immune evasion	9
tyrosine kinases	9
protein evolution	9
previous study	9
cancer cell	9
past years	9
complement system	9
solution structure	9
site motifs	9
infectious disease	9
gene encoding	9
high species	9
catalytic sites	9
virus serotype	9
golgi network	9
binding kinetics	9
primary structure	9
fold change	9
purified using	9
ice scrape	9
methylation sites	9
cell adhesion	9
frameshift errors	9
web service	9
protein stability	9
western blot	9
serine proteinases	9
complex structures	9
synonymous substitutions	9
downstream secondary	9
associated protein	9
negative control	9
different types	9
resolution crystal	9
ucc uga	9
ab initio	9
data extraction	9
available data	9
water molecules	9
cleavage specificity	9
viral communities	9
proteins using	9
nucleotide binding	9
recent data	9
forest species	9
norovirus cl	8
traditionally managed	8
pleural fluid	8
publicly available	8
protein tyrosine	8
novo design	8
neutralizing antibodies	8
programmed translational	8
analysis using	8
molecular interactions	8
cysteine protease	8
provide new	8
translational frameshifting	8
quality control	8
located within	8
thermal unfolding	8
reverse transcriptase	8
using circular	8
among different	8
virus entry	8
directed evolution	8
data indicate	8
acid residue	8
geometric hashing	8
takes place	8
highly variable	8
ace protein	8
health organization	8
protein molecules	8
will present	8
viral infection	8
dna viruses	8
previous analyses	8
influenza hemagglutinin	8
endothelial cells	8
critical role	8
site selection	8
binding residues	8
proteolytic regulation	8
nonsense suppression	8
various cellular	8
time points	8
science foundation	8
innate immunity	8
linear combination	8
zinc hook	8
chicken trachea	8
transversion rate	8
stress conditions	8
carboxypeptidase ii	8
managed hay	8
peptide bond	8
acid extraction	8
basic residues	8
final volume	8
nucleotide substitution	8
rhesus macaques	8
scanning window	8
throughput screening	8
relative accessibility	8
laboratory director	8
programmed frameshift	8
expression system	8
sigma factors	8
several proteins	8
uv cd	8
child health	8
site motif	8
field layer	8
atomic resolution	8
since abandonment	8
structure analysis	8
heat shock	8
low molecular	8
targeting motif	8
civic society	8
free radical	8
tau protein	8
experimental results	8
selective pressures	8
may provide	8
physiological processes	8
findings indicate	8
ubiquitin proteasome	8
successfully used	8
glutamate carboxypeptidase	8
recent study	8
based protein	8
likelihood scores	8
type enzyme	8
host range	8
new method	8
cysteine residues	8
zoonotic viruses	8
fold increase	8
calculated using	8
sites across	8
different protein	8
classification frameworks	8
fold higher	8
binding pockets	8
four residues	8
group i	8
risk assessment	8
subcellular localization	8
molecular function	8
direct interaction	8
sites found	8
modified nucleotides	8
interacting partners	8
biological function	8
respiratory disease	8
proteinase inhibitor	8
translational accuracy	8
allosteric targeting	8
search engine	8
surface patches	8
community structure	8
pc reactivity	8
northern territory	8
monterey sardine	8
among others	8
site contacts	8
spearman rank	8
human plasma	8
genetic conflicts	8
single molecule	8
precursor proteins	8
glycan structures	8
genetically encoded	8
ribosomal frameshift	8
expression profile	8
binding motif	8
genetic code	8
environmental parameters	8
heavy chain	8
molecular determinants	8
table shows	8
cell viability	8
commonly used	8
tyrosine kinase	8
different species	8
spacer adoption	8
potential therapeutic	8
class i	8
two subunits	8
cold adaptation	8
rna fragments	8
curriculum completion	8
unmodified rbd	8
ray structure	8
higher accessibility	8
microbial community	8
putative rna	8
gcp ii	8
cell growth	8
known proteolytic	8
regulatory proteins	8
increased affinity	8
three times	8
much higher	8
care service	8
negative set	8
antiviral drugs	8
conserved residues	8
disulfide bridges	8
transferrin receptor	8
polyacrylamide gel	8
proteolytic activity	8
silkworm ptth	8
coronavirus main	8
ace receptor	8
much lower	8
tourism economies	8
floating catchment	8
amber force	8
rna degradation	8
recent work	8
binding properties	8
streptococcus pneumoniae	8
specific cyber	8
studies will	8
mapped onto	8
transect frequency	8
quaternary structure	8
like particles	8
provide valuable	8
acid substitution	8
trypsin i	8
hong kong	8
site may	8
identified using	8
leukemia virus	8
nmr structure	8
protease domain	8
host species	8
statistical methods	8
viral envelope	8
perch study	8
nmr studies	8
canopy cover	8
intrinsic disorder	8
muscular dystrophy	8
open access	8
frequency distribution	7
cd spectroscopy	7
recent advances	7
previously shown	7
like proteinases	7
little effect	7
study also	7
tested using	7
ideal best	7
hook domain	7
west bengal	7
ace sequences	7
terminal part	7
binding mode	7
malicious web	7
protein cleavage	7
human papillomavirus	7
individual proteins	7
years ago	7
laboratory methods	7
structure elements	7
strongly associated	7
atp binding	7
across different	7
virus neuraminidase	7
online learning	7
limited proteolysis	7
hcd lel	7
boat conformation	7
coronavirus hku	7
bacillus subtilis	7
protein capsules	7
proline residues	7
like serine	7
invasive species	7
oligomerization state	7
habitat types	7
two highly	7
hemorrhagic fever	7
residues involved	7
tim barrel	7
study group	7
mm dtt	7
computational approaches	7
ligand atom	7
high sensitivity	7
social engineering	7
human receptor	7
care services	7
polymorphic sites	7
sequence variation	7
viral infections	7
genes involved	7
positive charge	7
receptor protein	7
binding modes	7
designed protein	7
will allow	7
selection pressures	7
time since	7
oxidative damage	7
years since	7
two mutants	7
acidic residues	7
structurally similar	7
cell membranes	7
structural motif	7
experimental evidence	7
start site	7
studies showed	7
per km	7
cyber threat	7
functional groups	7
surface residues	7
specific locations	7
well understood	7
case studies	7
family proteins	7
ratio tests	7
based biosensor	7
fluorescence spectroscopy	7
also predicted	7
state university	7
common ancestor	7
rate ratio	7
associated herpesvirus	7
contains two	7
different binding	7
studies indicate	7
broad range	7
hydrophobic amino	7
qualitative research	7
influenza drugs	7
experimentally determined	7
adopter sites	7
frad site	7
weed classification	7
aut onoma	7
drug delivery	7
protein expressed	7
cell proteases	7
viral attachment	7
polyubiquitin chains	7
gel filtration	7
relatively small	7
labor force	7
mutagenesis studies	7
alanine scanning	7
islet amyloid	7
catalytic cysteine	7
proteins containing	7
income equality	7
translational fidelity	7
subcellular location	7
type glycans	7
sensor proteins	7
integral membrane	7
like pcs	7
biophysical techniques	7
forest university	7
trna slippage	7
dhex hexnac	7
high molecular	7
vice versa	7
biological systems	7
protein substrates	7
well established	7
cov nsp	7
additional information	7
structural determinants	7
translational modifications	7
site trnas	7
united nations	7
private sector	7
network analysis	7
fatty acid	7
infection studies	7
folding cooperativity	7
different methods	7
main proteinase	7
tourism receipts	7
molecular modeling	7
correlation coefficient	7
female catkin	7
hybrid model	7
hcv ns	7
like coronavirus	7
mm nacl	7
future work	7
functional characterization	7
homologous proteins	7
gives rise	7
primary sequence	7
vitro studies	7
pd egfp	7
long term	7
physiological role	7
vitro transcription	7
sequence homology	7
envelope proteins	7
observed species	7
life history	7
active enzyme	7
local structural	7
catalytically active	7
proteolytic activation	7
cov spike	7
consensus sequence	7
salt bridges	7
research evidence	7
hot spot	7
like protein	7
detected using	7
protein kinase	7
two main	7
determined using	7
gene ontology	7
atom pairs	7
moonlighting proteins	7
based drug	7
treatment failure	7
antibody binding	7
cleavage efficiency	7
per capita	7
three groups	7
focus group	7
cyt cb	7
freshwater ecosystems	7
virulence factors	7
molten globule	7
exchange chromatography	7
proteins interact	7
catalytic mechanism	7
great ape	7
results presented	7
may explain	7
ancestral sequence	7
generated using	7
reverse transcription	7
analysis indicates	7
like proteins	7
synthetic peptides	7
healthcare services	7
human trypsin	7
occupancy status	7
functional domains	7
great interest	7
previously identified	7
active peptides	7
mutational analysis	7
dynamic light	7
preliminary results	7
total species	7
unconventional decoding	7
specific sites	7
healthcare centres	7
si variants	7
folded protein	7
whole blood	7
structural alignment	7
ray crystallographic	7
calcium binding	7
tourism destination	7
avian infectious	7
ace gene	7
null model	7
cd spectra	7
specific inhibitors	7
different stages	7
insertion construct	7
also provided	7
molecular surface	7
enteropeptidase light	7
protein modeling	7
sequence divergence	7
gnsp mh	7
orf ab	7
folded proteins	7
method uses	7
gain insight	7
binding inhibitors	7
protein rbd	7
real time	7
using human	7
last years	7
tropical savannas	7
tau aggregation	7
wobble pair	7
necrotic cell	7
results revealed	7
polypeptide chain	7
sialylated glycans	7
basic protein	7
quality assurance	7
structural properties	7
human protein	7
recently developed	7
ion channel	7
also showed	7
proteins based	7
strong evidence	7
respiratory syncytial	7
der maarel	7
also show	7
evolutionary dynamics	7
much less	7
aromatic residues	7
chair conformation	7
single nucleotide	7
accessory proteins	7
least three	7
two cleavage	7
attachment proteins	7
protein structural	7
care facilities	7
across sites	7
different sites	7
wake forest	7
disorder propensities	7
tourism supply	7
negative selection	7
conformational flexibility	7
culture supernatant	7
energy landscape	7
functional residues	6
cellular receptor	6
polypeptide chains	6
quantile regression	6
viral glycans	6
symmetry axis	6
human pathogens	6
read count	6
higher affinity	6
electrostatic potential	6
island perspective	6
yale university	6
ray diffraction	6
computer simulation	6
specific membrane	6
evaluated using	6
aspartic acid	6
results will	6
two steps	6
highest species	6
human proteins	6
na structure	6
data points	6
squamous cell	6
likelihood method	6
protein molecule	6
dimerization domain	6
river system	6
fold wild	6
results support	6
deep sequencing	6
detection names	6
adenosine deamination	6
lung aspirate	6
fiber knob	6
potent inhibitors	6
ph range	6
ruthenium glycosylated	6
distribution histogram	6
reconstructed ancestral	6
final concentration	6
inhibitor complex	6
antimicrobial peptide	6
shortest path	6
transmembrane protein	6
hinge region	6
rate constants	6
evolutionary trace	6
graph theory	6
intermolecular interactions	6
regression analysis	6
maximum range	6
great impact	6
empirical bayes	6
unfolded state	6
type ribosomes	6
powerful tool	6
directly interact	6
drug candidates	6
rcsb pdb	6
transmembrane domains	6
fold rotational	6
tourism density	6
low affinity	6
two major	6
glycosylated porphyrin	6
special features	6
syncytial virus	6
docking methods	6
site species	6
coiled coil	6
explicit solvent	6
performance evaluation	6
spatial distribution	6
binding free	6
human lysozyme	6
spike proteins	6
encoded proteinases	6
genbank description	6
cd receptor	6
bifunctional enzyme	6
structural differences	6
slippery site	6
vh sequences	6
geographical information	6
experimental studies	6
restriction factors	6
concentrated kurozu	6
functional receptor	6
proteins whose	6
tested whether	6
ang i	6
ms ms	6
transition rates	6
download buttons	6
spatial scales	6
conserved domain	6
commons attribution	6
metal ion	6
comparative study	6
one order	6
unnatural amino	6
residential areas	6
point mutation	6
high confidence	6
coding sequence	6
glutamic acid	6
kagoshima university	6
recognition sites	6
three species	6
sh domain	6
biological activity	6
myelin basic	6
protein functional	6
substrate recognition	6
standard deviation	6
binding function	6
will help	6
chain patterns	6
molecular diagnostics	6
mean values	6
luciferase signal	6
national institute	6
pseaa composition	6
plasmid pet	6
dna complexes	6
hydrophobic core	6
main antecedents	6
bat origin	6
fake removal	6
well conserved	6
tourism governance	6
evidence suggests	6
dimer formation	6
based approach	6
highly expressed	6
function relationship	6
rhesus macaque	6
likelihood score	6
causing mutations	6
stress response	6
resolution structures	6
sars virus	6
important sites	6
rna genome	6
programmed cell	6
cell division	6
functional motifs	6
competing interests	6
bat communities	6
terminal end	6
substitution rate	6
start codon	6
gfp mrna	6
mers clade	6
biosensor assay	6
use land	6
lure users	6
uga codon	6
innate immune	6
inhibitory effect	6
em structures	6
pediatric emergency	6
coronavirus mhv	6
catalytic domains	6
cys residues	6
shannon diversity	6
identify specific	6
transcription start	6
growing season	6
deuterium exchange	6
specific models	6
key factor	6
inclusive growth	6
extracellular domain	6
acute asthma	6
abandoned sites	6
agricultural landscape	6
polymerase iii	6
island economies	6
marked validated	6
sh domains	6
viruses replicating	6
approved drugs	6
mean square	6
new class	6
frame recognition	6
highly ranked	6
systems biology	6
precursor protein	6
encodes mhv	6
computational docking	6
will also	6
enveloped virus	6
emerging zoonotic	6
polyamine levels	6
induced unfolding	6
virus capsid	6
essential role	6
acid side	6
malware detection	6
geographic information	6
site directed	6
nt insertion	6
significantly greater	6
directly involved	6
cell tropism	6
early adopting	6
catalytic residue	6
homology modeling	6
weighted linear	6
protein levels	6
first axis	6
cancer patients	6
infection alerts	6
potential sites	6
coding genes	6
supplementary information	6
three recombinant	6
research institute	6
economic development	6
will show	6
carrying capacity	6
studies using	6
urban areas	6
min post	6
second step	6
three categories	6
pka values	6
markov transient	6
many viruses	6
cell extracts	6
sequence pattern	6
human diseases	6
body docking	6
binding interface	6
per sample	6
docking studies	6
signaling pathway	6
tourism policy	6
entry mechanism	6
native substrate	6
fold symmetry	6
human respiratory	6
tourism markets	6
bond propensities	6
sardinops sagax	6
functional studies	6
deletion mutants	6
transmembrane region	6
tree canopy	6
remains unknown	6
luciferase gene	6
sequential structural	6
human host	6
host proteins	6
kda protein	6
arginine residues	6
human influenza	6
nmr data	6
recombinant proteinase	6
rna replication	6
protein unfolding	6
lysozyme solution	6
trypsin iii	6
protein product	6
gene sequences	6
human transcripts	6
quadrat cover	6
clinical rotations	6
nmr spectra	6
significantly reduced	6
different families	6
national tourism	6
one site	6
degradation pathway	6
susceptibility testing	6
ligand association	6
mediated cleavage	6
catalytic properties	6
important factor	6
sg proteins	6
specific selection	6
human cell	6
calcium carbonate	6
four groups	6
closed conformation	6
different cell	6
detailed analysis	6
water bodies	6
raw data	6
zinc binding	6
antimicrobial susceptibility	6
supply chain	6
gads sh	6
may affect	6
commons license	6
small intestine	6
known structure	6
significantly increased	6
porcine respiratory	6
pdz domain	6
lysis buffer	6
additional cleavage	6
new model	6
protein fragments	6
interface residues	6
rensselaer polytechnic	6
structural analyses	6
different proteins	6
heterologous expression	6
functional properties	6
fission yeast	6
annotation lines	6
carbohydrate interactions	6
large domain	6
artificial neural	6
like fold	6
live cells	6
fret assay	6
biochemical characterization	6
sustainable tourism	6
grb sh	6
site score	6
polymerase gene	6
terminal proteolytic	6
tertiary structural	6
step calculate	6
heparan sulfate	6
different concentrations	6
wall binding	6
currently available	6
important roles	6
functional site	6
processing events	6
translation reactions	6
clinical course	6
structural similarities	6
folded states	6
statistical significance	6
triple mutant	6
multibasic cleavage	6
based assays	6
druggable sites	6
trypsin inhibitor	6
mean number	6
site specific	6
associated serine	6
type levels	6
novel method	6
western blotting	6
living relatives	6
also shown	6
identify frad	6
two sets	6
structure comparison	6
sampling sites	6
activity towards	6
amyloid fibril	6
real tourism	6
rbd proteins	6
based method	6
evolved adaptively	6
invertebrate fauna	6
thumb subdomain	6
biological functions	6
proteasome pathway	6
simulation studies	6
residues within	6
protease inhibition	6
coronavirus genome	6
protein pairs	6
evolutionary analyses	6
much larger	6
protein regions	6
protein domain	6
frameshift event	6
quadrat frequency	6
yeast ribosomal	6
may become	6
atomic level	6
dimeric cyt	6
sodium acetate	6
viral products	6
amyloid polypeptide	6
two types	6
protein backbone	6
northumbrian river	6
reactive epitopes	6
selected residues	6
related coronaviruses	6
protein concentration	6
nonsynonymous substitutions	6
enabled us	6
classifier trained	6
liver disease	6
functional proteins	6
binding activity	6
proteins within	6
genome sequences	6
three sites	6
river coquet	6
protein domains	6
mammal fauna	6
therapeutic sites	6
etiology research	6
economic perspective	6
proton solvation	6
closest living	6
institutional capture	6
sequence specificity	6
multivariate techniques	6
surface water	6
ml method	6
patient care	6
function relationships	6
correspondence analysis	6
luciferase reporter	6
aruba tourism	6
green fluorescent	6
conformational states	6
crystallographic structure	6
adopt mdi	6
geospatial distribution	6
virus sequences	6
give rise	6
np op	5
predicted based	5
solvent accessibility	5
female catkins	5
emerging infectious	5
allosteric communication	5
coronavirus associated	5
peptide bonds	5
vaccine efficacy	5
type inhibitors	5
signalling pathways	5
made using	5
three tools	5
percent occupancy	5
formic acid	5
functional protein	5
domain name	5
play key	5
correlation spectroscopy	5
glutamate receptor	5
lipid peroxidation	5
second sialic	5
bound form	5
possible cleavage	5
ph values	5
evidence indicates	5
arms races	5
potential role	5
one another	5
based model	5
binding order	5
rate bias	5
negative impact	5
initiation factor	5
aspirate specimens	5
help us	5
using molecular	5
rare hay	5
key residues	5
deubiquitinating enzyme	5
will discuss	5
regulatory enforcement	5
sagax caerulea	5
protein misfolding	5
molecular surfaces	5
factor xa	5
fern andez	5
pc pace	5
domain interactions	5
every protein	5
sequencing data	5
starfish compound	5
binding characteristics	5
erk kinase	5
bat sars	5
attachment protein	5
political economy	5
will contribute	5
trna phe	5
heptameric sequences	5
aggregation propensity	5
level iterative	5
complete sequence	5
network model	5
low temperature	5
based inhibitors	5
cleavage sequence	5
scarce species	5
cov infection	5
mature proteins	5
tryptophan fluorescence	5
acid proteases	5
like endoprotease	5
actively crawled	5
peptide libraries	5
rous sarcoma	5
substrate specificities	5
based tourism	5
structural polyprotein	5
lysine residue	5
new therapeutic	5
polymerase chain	5
viral populations	5
transfer rna	5
scoring function	5
data will	5
detection limit	5
research design	5
conserved cysteine	5
endogenous mrnas	5
thermal denaturation	5
functional features	5
electron transfer	5
neutralizing antibody	5
second one	5
methyl antisense	5
identical residues	5
practice environment	5
ter braak	5
vector control	5
healthcare centre	5
stranded dna	5
transfected cells	5
structural nadp	5
homologous sequences	5
nucleotide similarity	5
potential drugs	5
crawled web	5
analysis based	5
therapeutic agents	5
convertase furin	5
pc selectivity	5
coagulation factor	5
coupled transcription	5
physiological functions	5
microscale thermophoresis	5
structure determination	5
anticodon interactions	5
risk factors	5
several important	5
herpes simplex	5
small islands	5
individual sites	5
known functional	5
globular proteins	5
signal sequence	5
total population	5
bayes empirical	5
dna sequence	5
cell fusion	5
avian paramyxovirus	5
mobile phone	5
terminal domains	5
respiratory specimens	5
will need	5
disease control	5
psylla palmeni	5
probable bat	5
control cells	5
results reveal	5
obtained using	5
integrating biology	5
modification sites	5
one binding	5
given site	5
detailed characterization	5
three domains	5
dna polymerase	5
acid change	5
hydrophobic interaction	5
fake infection	5
potential drug	5
national park	5
two states	5
functional regions	5
glycoprotein gp	5
way anova	5
social inequality	5
site sequence	5
like receptor	5
semliki forest	5
hela cell	5
snare proteins	5
highly similar	5
vast majority	5
ideal worst	5
selection sites	5
distance dispersal	5
crystallographic structures	5
queen hypothesis	5
approach based	5
one subunit	5
accession numbers	5
prime side	5
best site	5
eukaryotic protein	5
arabidopsis thaliana	5
del rdrp	5
depth case	5
multidomain proteins	5
distributed across	5
site level	5
methods discussed	5
malware removal	5
allosteric regulation	5
protein scaffolds	5
two thirds	5
many viral	5
mammalian genes	5
extant tims	5
caribbean site	5
high concentrations	5
high efficiency	5
prolyl oligopeptidase	5
dynamics simulation	5
master plan	5
bd trajectories	5
protein concentrations	5
two groups	5
every day	5
larger number	5
based molecular	5
well known	5
web application	5
allosteric binding	5
wt hiat	5
random forest	5
online version	5
specific variants	5
enable researchers	5
protein arginine	5
infection susceptibility	5
terminal signal	5
cleavage fragment	5
using mdi	5
identify possible	5
antigen complex	5
tourism institutions	5
animal models	5
scanning calorimetry	5
regulatory subunit	5
folding mechanism	5
track diagnostics	5
containing proteins	5
strong consensus	5
novel approach	5
induced conformational	5
sheet structure	5
putative functional	5
relatively low	5
dependent small	5
infectious agents	5
alternative approach	5
table lists	5
two pc	5
riparian zone	5
new generation	5
yeast cells	5
materials science	5
salt bridge	5
test samples	5
surface regions	5
also provide	5
also present	5
following treatment	5
tourism overshoot	5
aqueous solution	5
assay system	5
nmr experiments	5
protein recognition	5
two models	5
structural protein	5
rapid degradation	5
blended learning	5
peptide hormones	5
comparative analysis	5
santa cruz	5
globule state	5
similar functions	5
sampling points	5
three main	5
reaction system	5
virus genome	5
inhibition assays	5
affinity interactions	5
electrostatic repulsion	5
five residues	5
ion exchange	5
fluorescence correlation	5
zinc ion	5
disordered domain	5
often used	5
putative sites	5
virome community	5
binding module	5
initial results	5
coronavirus isolate	5
may still	5
growth rate	5
phenotypic effects	5
proteasome inhibitors	5
proteins without	5
polypeptide encoded	5
species within	5
protein chain	5
specific functions	5
bound state	5
observed increase	5
species barrier	5
differences may	5
disease incidence	5
international committee	5
using qpcr	5
predicted allosteric	5
one type	5
environmental factors	5
local three	5
species based	5
identi ed	5
flexible regions	5
salix species	5
linked sialic	5
one protein	5
pcs perform	5
allocating new	5
cell proliferation	5
receptor tyrosine	5
computational protein	5
secondary sites	5
starting point	5
motor neurons	5
vector machine	5
drosophila melanogaster	5
stage species	5
hace receptor	5
legitimate sites	5
mediated activation	5
results shown	5
terminal cleavage	5
anoxia stress	5
binary matrices	5
infect human	5
functional relationship	5
murine leukemia	5
reads matrix	5
sequences within	5
cancer types	5
circadian rhythms	5
reticulocyte lysate	5
site profiling	5
relatively stable	5
correlation analysis	5
multiple sites	5
expressing wild	5
rna sequences	5
residue interactions	5
synthetic biology	5
proteins may	5
schedule cohort	5
path network	5
annotate protein	5
recombinant expression	5
plasma membrane	5
viral sequences	5
biophysical properties	5
translation termination	5
cellular membrane	5
approximate methods	5
reference genome	5
may vary	5
lipid bilayer	5
become available	5
intermolecular disulfide	5
pl pro	5
cognate trna	5
calcium ion	5
fibroblast growth	5
biochemical analysis	5
vector machines	5
known frameshift	5
survey data	5
selective inhibitors	5
coronavirus clpro	5
predicted molecular	5
natural host	5
large numbers	5
barrel proteins	5
anticodon interaction	5
observed number	5
physicochemical features	5
liver proteins	5
catalytically inactive	5
examples include	5
highly dynamic	5
specific amino	5
parsimony method	5
interactions within	5
might also	5
evolutionary conservation	5
base pairs	5
target site	5
increasing amounts	5
membrane antigen	5
binding partner	5
evolutionary pressure	5
available structural	5
atomic model	5
homology models	5
protein secondary	5
linker proteins	5
newly synthesized	5
unique domain	5
human populations	5
methyltrans ferase	5
tourism destinations	5
mrna methylation	5
various biological	5
sheds light	5
genomic characterization	5
cellular proteins	5
expression vector	5
physiological conditions	5
legitimate av	5
care facility	5
saudi arabia	5
new sites	5
centro nacional	5
natural products	5
viral polyprotein	5
codon usage	5
least partially	5
ns pro	5
gan hemts	5
surface receptors	5
relaxation dispersion	5
rapid evolution	5
structural models	5
less effective	5
nucleotide sequence	5
mutant ribosomes	5
intermediate host	5
episodic selection	5
five countries	5
vitro evolution	5
severe pneumonia	5
low energy	5
site cleft	5
aligned using	5
three dimensional	5
recent reports	5
tax revenues	5
like enzymes	5
res doi	5
large variety	5
sodium channel	5
kilodalton polypeptide	5
dna conjugates	5
visible light	5
local surface	5
ubiquitin system	5
molecular dynamic	5
three frameworks	5
translation system	5
early stage	5
potential targets	5
various diseases	5
ms analysis	5
per year	5
coronavirus proteinase	5
ligand interactions	5
pace pc	5
viral signal	5
protein chains	5
binding region	5
growth rates	5
residue conservation	5
regions may	5
biochemical pathways	5
evolutionary context	5
messenger rnas	5
double stranded	5
human transmission	5
amide hydrogen	5
basic residue	5
computational approach	5
national institutes	5
monoclonal antibody	5
medical education	5
may help	5
ideal solution	5
cysteine cathepsins	5
reads per	5
humoral immune	5
stanford university	5
virus fusion	5
anticodon complex	5
ang ii	5
complex role	5
primary sequences	5
predicted using	5
rat brain	5
antimicrobial peptides	5
viral surface	5
protein secretion	5
specific binding	5
gene regulation	5
sequence conservation	5
coronavirus nsp	5
rot fungi	5
rna synthesis	5
virus population	5
protease activities	5
still unknown	5
protein turnover	5
essential oil	5
structural flexibility	5
including known	5
transient analysis	5
replicase polyproteins	5
tumour cells	5
many sites	5
memory cd	5
sox samples	5
provide insights	5
three nucleotides	5
slow tight	5
local community	5
also detected	5
software suite	5
global pandemic	5
arginine residue	5
temperature factors	5
norwalk virus	5
data presented	5
antigen presentation	5
several genes	5
install fake	5
chain reaction	5
zinc ions	5
reporter protein	5
simplex virus	5
active form	5
structural model	5
binding event	5
coronavirus ibv	5
increasing evidence	5
without prior	5
acidic conditions	5
predicting dna	5
fully understood	5
representative structure	5
natural substrate	5
good match	5
critical binding	5
carbohydrate binding	5
cleavages sites	5
recombinant human	5
prediction using	5
chemical properties	5
evolutionary information	5
far uv	5
commonly found	5
tourism export	5
buffer glycerol	5
structural dynamics	5
different reservoirs	5
substitution model	5
ace activity	5
respiratory therapists	5
uga shift	5
proteins protein	5
small subunit	5
bd simulations	5
fluorescent proteins	5
crawled data	5
virus strain	5
hiv infection	5
solvent environment	5
programmed ribosomal	5
specific activity	5
two dissociation	5
absolute reads	5
also analyzed	5
current outbreak	5
synonymous site	5
genes encoding	5
polytechnic institute	5
bacterial cell	5
great potential	5
frozen food	5
brain tumors	5
residues located	5
data show	5
folding transition	5
statistical models	5
adaptive molecular	5
upper reaches	5
virus evolution	5
restriction enzyme	5
pc pc	5
relatively high	5
structural templates	5
laboratory values	5
measurement study	5
simulations suggest	5
use patterns	5
three independent	5
different land	5
spatial data	5
sites flanking	5
substrate sequence	5
deacylated trna	5
sensor surface	5
plasmid dna	5
thermodynamic stability	5
host factors	5
analysis reveals	5
terminal gst	5
evolutionary genetics	5
functional roles	5
atom molecular	5
targeted protein	5
sea level	5
contact residues	5
gfp samples	5
doped nano	5
alien species	5
kinetic analysis	5
integral part	5
acids long	5
two novel	5
relevant glycan	5
provide evidence	5
loop geometries	5
related proteins	5
proteolysis activity	5
staphylococcus aureus	5
culture medium	5
native form	5
functionally relevant	5
classification systems	5
peptide ligands	5
length protein	5
force participation	5
substrate hydrolysis	5
molecular simulations	5
sites occurred	5
well studied	5
direct contact	5
synonymous substitution	5
different substrates	5
avian coronavirus	5
function annotation	5
base pairing	5
immediately prior	5
tm domain	5
online curricula	5
search condition	5
protein conformation	5
silico docking	5