trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
the number of	547
as well as	514
the presence of	479
in order to	470
based on the	366
one of the	360
genome sequence of	258
the development of	255
the use of	227
of the protein	227
sequence of the	220
analysis of the	211
in this study	211
can be used	191
due to the	188
a number of	187
structure of the	181
amino acid sequence	177
a variety of	176
it has been	161
the synthesis of	161
in the presence	160
the amino acid	155
a set of	154
be used to	152
in addition to	149
part of the	149
found to be	146
the formation of	145
of amino acids	144
the human genome	143
of dna sequences	143
the role of	142
in terms of	134
each of the	134
according to the	133
involved in the	133
of the human	131
hepatitis c virus	129
of a novel	128
of the sequences	127
the effect of	127
that can be	126
the structure of	125
the case of	125
such as the	125
on the other	123
a series of	123
the other hand	118
complete genome sequence	116
in the case	115
well as the	115
to determine the	115
large number of	111
was used to	111
graphical representation of	111
some of the	110
sequences of the	109
of the most	109
the sequence of	108
in the present	108
the analysis of	108
amino acid sequences	108
of the two	106
of the genome	106
in this work	106
role in the	105
of protein sequences	104
the identification of	104
there is a	104
sequences in the	103
most of the	102
has been shown	101
amino acid residues	101
a total of	100
of the sequence	100
the present study	100
been shown to	99
found in the	99
to that of	99
d graphical representation	99
the design of	99
compared to the	99
the results of	98
present in the	97
shown to be	97
the absence of	97
of the virus	97
region of the	97
to be a	96
is based on	95
with respect to	95
of the peptide	95
was found to	94
used in the	94
the fact that	94
the importance of	94
of a protein	92
of amino acid	92
as a result	92
based on a	91
end of the	91
the effects of	91
severe acute respiratory	90
multiple sequence alignment	89
acute respiratory syndrome	89
is one of	89
the ability to	88
in the sequence	87
associated with the	87
in which the	87
have shown that	87
members of the	85
a large number	85
the active site	84
in the same	84
of the viral	83
to investigate the	83
the evolution of	82
showed that the	81
the expression of	81
the mechanism of	81
related to the	79
to identify the	78
the size of	77
we found that	77
understanding of the	76
sequences based on	76
to study the	76
of hepatitis c	76
and in the	76
that of the	75
of the same	75
were found to	75
nucleotide sequence of	74
an important role	74
a and b	74
be used for	74
changes in the	74
the aim of	73
the process of	73
the basis of	73
show that the	73
of the three	72
as shown in	72
the production of	72
the activity of	72
it is possible	71
the end of	71
the discovery of	71
properties of the	71
the length of	71
a combination of	71
there is no	70
of the first	70
the detection of	70
in this paper	70
characterization of the	69
the distribution of	69
are involved in	69
was carried out	69
activity of the	69
the set of	68
in the absence	68
the function of	68
the sequences of	68
sequence of a	68
because of the	68
suggest that the	67
for the development	67
the ability of	67
function of the	67
were used to	67
representation of dna	67
the study of	66
derived from the	66
number of sequences	66
between the two	65
size of the	65
were able to	65
important role in	64
the application of	64
the amount of	64
responsible for the	64
the rate of	63
be involved in	63
shown in fig	63
known to be	62
the genome of	62
can be found	62
similar to that	62
revealed that the	62
the binding of	62
used as a	62
of the p	62
it can be	62
length of the	61
is used to	61
on the basis	61
the surface of	61
the level of	61
used for the	61
all of the	61
have been developed	61
and characterization of	61
to understand the	60
genome sequences of	60
parts of the	60
the existence of	60
are able to	60
corresponding to the	60
depending on the	59
seems to be	59
need to be	59
of a new	59
it is not	59
member of the	58
that have been	58
the majority of	58
wide range of	58
of this study	58
by means of	58
the treatment of	58
it is a	58
on the surface	57
in contrast to	57
have been identified	57
nature of the	57
is shown in	57
is the most	57
identification of a	57
in the first	56
information about the	56
phase peptide synthesis	56
consistent with the	56
the interaction of	56
evolution of the	56
we show that	55
a range of	55
results suggest that	55
of the n	55
representation of protein	55
can also be	55
at the same	55
the phylogenetic tree	55
expression of the	54
have been used	54
shown in figure	54
the accuracy of	54
in the database	54
a role in	53
of the proteins	53
in the human	53
presence of a	53
the range of	53
to be the	53
are known to	53
a wide range	53
will be discussed	53
the secondary structure	52
we report the	52
which is a	52
as compared to	52
results show that	52
the degree of	52
and it is	52
open reading frames	52
which is the	51
and analysis of	51
the fi rst	51
the nature of	51
some of these	51
found that the	50
was supported by	50
the possibility of	50
of a sequence	50
is involved in	50
which can be	50
referred to as	50
sequences can be	50
of the sars	50
a group of	50
comparison of the	50
located in the	49
shown that the	49
phylogenetic analysis of	49
crystal structure of	49
role of the	49
could be used	49
respiratory syndrome coronavirus	49
is able to	49
the regulation of	49
closely related to	49
in the protein	48
x and y	48
was used as	48
been used to	48
the genome sequence	48
of the s	48
sequence analysis of	48
are shown in	48
the most common	48
has been used	48
of the c	48
in vitro and	48
of the disease	48
the performance of	48
sequences that are	47
the quality of	47
use of the	47
suggests that the	47
be used as	47
regions of the	47
is known to	47
of the four	47
this study was	47
of the data	47
obtained from the	47
supported by the	46
we have developed	46
at least one	46
of a single	46
residues in the	46
appears to be	46
many of the	46
be found in	46
distribution of the	46
similar to the	46
amino acids in	46
of all the	46
the most abundant	46
of the target	46
sequence in the	46
the result of	46
dependent on the	45
in recent years	45
the most important	45
characterization of a	45
for the first	45
s and s	45
results indicate that	45
in this case	45
position of the	45
the viral genome	45
is possible to	45
for each of	45
shown in table	45
of the peptides	45
in the development	45
and can be	44
were obtained from	44
the complete genome	44
is represented by	44
and evolution of	44
this work was	44
led to the	44
to each other	44
the frequency of	44
has not been	44
study was to	44
mutations in the	44
a result of	44
this is the	44
the lack of	44
presence of the	44
immune repertoire classification	44
the structure and	43
sequences from the	43
the goal of	43
in response to	43
a member of	43
modern hopfield networks	43
of the enzyme	43
and in vivo	43
a family of	43
due to its	43
indicate that the	43
any of the	43
close to the	43
solid phase peptide	43
amino acid composition	43
increase in the	43
structural and functional	43
are used to	42
total number of	42
has also been	42
structures of the	42
de novo assembly	42
the genomes of	42
are based on	42
to evaluate the	42
in this section	42
to form a	42
of these peptides	42
polymerase chain reaction	42
a protein sequence	42
the interaction between	42
is the number	41
information on the	41
have been shown	41
of the dna	41
we have shown	41
based on their	41
considered to be	41
in the past	41
added to the	41
the generation of	41
national center for	41
of the rna	41
we have used	41
the same time	41
was used for	41
is composed of	41
is the first	40
will be presented	40
biological activity of	40
the amino acids	40
binding to the	40
differences in the	40
structure and function	40
an example of	40
dependent rna polymerase	40
draft genome sequence	40
vitro and in	40
one or more	40
observed in the	40
a dna sequence	40
to be involved	40
to predict the	40
insights into the	40
to increase the	39
was shown to	39
our understanding of	39
the introduction of	39
domain of the	39
the protein sequence	39
structure of a	39
due to their	39
the characterization of	39
be able to	39
the course of	39
in the following	39
the context of	39
that there is	39
of the amino	39
identified in the	39
in a single	39
the field of	39
the construction of	39
and amino acid	39
protein structure prediction	39
the present work	39
complete genome sequences	39
is present in	39
it is also	39
play an important	39
protein secondary structure	39
is an important	39
in some cases	38
alignment of the	38
have been found	38
in the last	38
formation of a	38
were carried out	38
that it is	38
been shown that	38
open reading frame	38
rest of the	38
to assess the	38
amino acids and	38
intrinsically disordered proteins	38
a list of	38
we developed a	38
from the same	38
a database of	38
is important to	38
at the c	38
center for biotechnology	38
in this context	38
we used the	38
proteins in the	37
human immunodeficiency virus	37
needs to be	37
is a key	37
is likely to	37
sequencing of the	37
likely to be	37
a pair of	37
in combination with	37
have also been	37
focused on the	37
have not been	37
stability of the	37
to find the	37
and its application	37
addition to the	37
be used in	37
than that of	37
this type of	37
the percentage of	37
the position of	36
is that the	36
the probability of	36
the potential to	36
secondary structure of	36
in case of	36
at the n	36
the rest of	36
the location of	36
quality of the	36
isolated from a	36
that there are	36
the university of	36
depends on the	36
development of a	36
aim of this	36
to improve the	36
the purpose of	36
effect of the	36
we conclude that	36
and the other	36
the total number	36
acid sequence of	36
to the same	36
the emergence of	36
respect to the	35
the stability of	35
nuclear magnetic resonance	35
the activation of	35
insight into the	35
key role in	35
belongs to the	35
identification of the	35
of the new	35
mechanism of action	35
to this end	35
the dna sequence	35
the utility of	35
small number of	35
dna sequences and	35
of gene expression	35
of a given	35
work was supported	35
to calculate the	35
state of the	35
the wild type	35
active site of	35
as a consequence	35
they can be	35
genome of the	35
belong to the	35
compared with the	35
analysis based on	34
we have found	34
to determine whether	34
i i i	34
in the genome	34
as in the	34
for the detection	34
have been proposed	34
the relationship between	34
it is important	34
model of the	34
there are many	34
can be considered	34
for the design	34
we present the	34
it is the	34
complete nucleotide sequence	34
of the major	34
by using the	34
in the literature	34
high degree of	34
can be applied	34
is associated with	34
were subjected to	34
formation of the	34
interaction with the	34
we find that	34
half of the	34
for the synthesis	34
the origin of	33
of these proteins	33
a key role	33
appear to be	33
of protein structure	33
to those of	33
of dna sequence	33
change in the	33
were identified in	33
the united states	33
in the n	33
at the end	33
and so on	33
of the different	33
in the range	33
were synthesized by	33
is characterized by	33
have to be	33
effect on the	33
is essential for	33
was performed using	33
has been proposed	33
the properties of	33
for a given	33
we are currently	33
may not be	33
the national center	33
of influenza a	33
the binding site	33
it should be	33
to be more	33
shows that the	33
is necessary to	33
correspond to the	33
determined by the	33
it was shown	33
development of new	33
is responsible for	33
the nucleotide sequence	33
and of the	33
the control of	32
for biotechnology information	32
high levels of	32
which may be	32
molecular dynamics simulations	32
this suggests that	32
knowledge of the	32
available in the	32
with an average	32
similar to those	32
followed by a	32
of the gene	32
it was found	32
of this work	32
in the second	32
site of the	32
belonging to the	32
wide variety of	32
each amino acid	32
the prediction of	32
in this way	32
the influence of	32
corresponds to the	32
data with implanted	32
of the corresponding	32
suggesting that the	32
of which are	32
amino acids are	32
is similar to	32
an increase in	32
features of the	32
to analyze the	32
included in the	32
protein sequences based	32
can lead to	32
the target protein	32
strand rna viruses	31
amino acid identity	31
to reduce the	31
the need for	31
of the model	31
in most cases	31
have been reported	31
which has been	31
of the resulting	31
of the other	31
in all the	31
the efficiency of	31
leads to the	31
the problem of	31
we note that	31
we investigated the	31
were used for	31
resulted in a	31
with the same	31
be related to	31
play a role	31
the first time	31
more than one	31
determination of the	31
we were able	31
the creation of	31
as an example	31
we use the	31
lead to the	31
when compared to	31
with that of	31
central nervous system	31
the s protein	31
out of the	31
of the number	31
of the tree	31
and that the	31
a subset of	31
be considered as	31
a wide variety	31
the query sequence	31
was found in	31
has been reported	31
as a model	31
to obtain the	31
represented by a	31
results in a	31
rna secondary structures	30
are present in	30
a phylogenetic tree	30
analysis of dna	30
plays an important	30
were shown to	30
as described in	30
to play a	30
of intrinsic disorder	30
human genome project	30
that they are	30
associated with a	30
accuracy of the	30
to estimate the	30
in the context	30
in other words	30
thought to be	30
the impact of	30
of viral rna	30
this study we	30
located at the	30
along with the	30
tomato leaf curl	30
was isolated from	30
of the structure	30
the crystal structure	30
interact with the	30
consists of a	30
the search for	30
of viral sequences	30
results of the	30
of a large	30
the form of	30
carried out by	30
with implanted signals	30
protein data bank	30
to be used	30
to obtain a	30
used in this	30
we have studied	30
in agreement with	29
the immune system	29
is the only	29
data not shown	29
to characterize the	29
of proteins and	29
the target sequence	29
in the s	29
so as to	29
a part of	29
the preparation of	29
large numbers of	29
that could be	29
the plasma membrane	29
for the treatment	29
machine learning methods	29
number of instances	29
listed in table	29
part of a	29
are associated with	29
there is an	29
and the number	29
derived from a	29
to test the	29
a new method	29
isolated from the	29
here we present	29
detected in the	29
to the development	29
of the samples	29
we have also	29
is required for	29
binding of the	29
we believe that	29
the conformation of	29
of at least	29
basis of the	29
of the family	29
many of these	28
the choice of	28
portion of the	28
the sequences are	28
sequences and their	28
as it is	28
in the other	28
the inhibition of	28
to compare the	28
intrinsic disorder in	28
was determined by	28
surface of the	28
may be a	28
in the viral	28
multiple sequence alignments	28
there has been	28
here we report	28
differences between the	28
is defined as	28
feline infectious peritonitis	28
of protein sequence	28
is a major	28
to interact with	28
these results suggest	28
in a protein	28
is consistent with	28
the availability of	28
our results show	28
this is a	28
for which the	28
studies of the	28
with the highest	28
the action of	28
contribute to the	28
different types of	28
in the two	28
are found in	28
the beginning of	28
are the most	28
of the cell	28
expected to be	28
used as the	28
the order of	28
well as in	27
the first step	27
be applied to	27
as part of	27
the concept of	27
is due to	27
the distance between	27
was able to	27
protein sequences and	27
the signal sequence	27
it may be	27
those of the	27
a novel coronavirus	27
in a variety	27
location of the	27
is important for	27
the spread of	27
their ability to	27
were used in	27
broad range of	27
because of their	27
a function of	27
only a small	27
the synthesis and	27
together with the	27
in a sequence	27
the sequence is	27
is believed to	27
identifi cation of	27
contrast to the	27
acid sequences of	27
is related to	27
to elucidate the	27
have the same	27
sequences with the	27
sites of the	27
been found to	27
synthesis of a	27
that the number	27
tool for the	27
note that the	27
of rna viruses	27
for the presence	27
and function of	27
are responsible for	27
protein in the	26
carried out using	26
genes involved in	26
dna sequences based	26
carried out in	26
the cost of	26
can be seen	26
is crucial for	26
in the brain	26
was found that	26
two types of	26
of the full	26
in the field	26
high affi nity	26
methods have been	26
protein structure and	26
the biological activity	26
are characterized by	26
two or more	26
we propose a	26
the proposed method	26
emerson et al	26
demonstrated that the	26
there are two	26
be explained by	26
bind to the	26
proteins involved in	26
there was a	26
described in the	26
virus variation resource	26
surface plasmon resonance	26
the hypothesis that	26
in presence of	26
analysis of a	26
insertions and deletions	26
similarity dissimilarity analysis	26
the vast majority	26
characterized by a	26
comparative analysis of	26
of the total	26
a collection of	26
to explore the	26
can be easily	26
it is known	26
vast majority of	26
in the process	26
were tested for	26
a consequence of	26
identical to the	26
a query sequence	26
of the binding	26
the potential of	26
influenza a viruses	26
c for min	26
for all the	26
results showed that	26
position in the	26
indicates that the	25
was shown that	25
to the protein	25
caused by the	25
of the molecular	25
characteristics of the	25
important for the	25
the genbank database	25
is in the	25
one of these	25
may be used	25
for the study	25
has been found	25
were identified as	25
terminus of the	25
the value of	25
be responsible for	25
basic local alignment	25
of the main	25
but it is	25
form of the	25
we have synthesized	25
in the regulation	25
the time of	25
interaction of the	25
alignment search tool	25
of the d	25
we propose that	25
the assembly of	25
applied to the	25
example of a	25
of sequences and	25
do not have	25
binding site of	25
which could be	25
of the a	25
because it is	25
also known as	25
that has been	25
the dna sequences	25
of the complete	25
the sum of	25
expressed in e	25
description of the	25
except for the	25
to the number	25
may also be	25
is expected to	25
for this purpose	25
indicating that the	25
it is necessary	25
been identified in	25
be noted that	25
of infectious diseases	25
east respiratory syndrome	25
is equal to	25
different from the	25
suggested that the	25
the need to	25
defined by the	25
the spike protein	25
activation of the	25
values of the	25
in each of	25
west nile virus	25
was observed in	25
case of the	25
is found in	25
of sequence data	25
the complexity of	25
has been developed	25
of the genus	25
could not be	25
of the ntp	25
method for the	24
serve as a	24
is supported by	24
majority of the	24
seem to be	24
middle east respiratory	24
local alignment search	24
to better understand	24
this work we	24
each of these	24
allowed us to	24
by a single	24
of these sequences	24
of these two	24
component of the	24
the incorporation of	24
of the e	24
we can see	24
of the coronavirus	24
of protein structures	24
the influenza virus	24
relative to the	24
in the formation	24
are consistent with	24
the extent of	24
this can be	24
study of the	24
is mediated by	24
attached to the	24
the sequences were	24
in the design	24
to address the	24
limited number of	24
to generate the	24
such as those	24
set of sequences	24
essential for the	24
the sequences in	24
in the cell	24
by the presence	24
to bind to	24
secondary structure prediction	24
that do not	24
the protein is	24
the growth of	24
the reference sequence	24
leads to a	24
amino acid residue	24
a comparison of	24
of the putative	24
is identical to	24
and has been	24
influenza a virus	24
is a very	24
and for the	24
background and aims	24
based on these	24
peptides and proteins	24
the occurrence of	24
two of the	24
the addition of	24
phylogenetic tree of	24
the interaction with	24
is not a	24
proteins can be	24
of the viruses	24
linked to the	24
we do not	24
of severe acute	24
in the genbank	24
in section a	24
we showed that	24
the in silico	24
to create a	24
well as a	23
p and p	23
viruses in the	23
of the present	23
use of a	23
development of the	23
interaction between the	23
as a function	23
of the membrane	23
studies have shown	23
better understanding of	23
a high degree	23
to develop a	23
properties of amino	23
would like to	23
the side chain	23
the structural and	23
provided by the	23
have been described	23
are likely to	23
mechanism of the	23
side of the	23
the immune response	23
of the native	23
at least two	23
only in the	23
at the level	23
represented by the	23
been applied to	23
the effectiveness of	23
that may be	23
the basis for	23
number of clusters	23
the similarity of	23
led to a	23
a sequence of	23
the combination of	23
that are not	23
repetitive dna sequences	23
the lengths of	23
a class of	23
generated by the	23
none of the	23
we present a	23
when compared with	23
amino acids with	23
we used a	23
in the form	23
taken into account	23
the method of	23
are similar to	23
of h n	23
followed by the	23
in the future	23
results in the	23
in the ncbi	23
based on sequence	23
an amino acid	23
details of the	23
of the l	23
our results suggest	23
can then be	23
to generate a	23
hrv and hev	23
genes in the	23
leading to the	23
has to be	23
next generation sequencing	23
the classification of	23
this approach is	23
the h n	23
is thought to	22
also be used	22
the graphical representation	22
residues of the	22
machine learning algorithms	22
of the non	22
were collected from	22
of the known	22
the determination of	22
used to identify	22
based sequence embedding	22
prediction of protein	22
can be viewed	22
access to the	22
used to generate	22
be divided into	22
we have identified	22
this work is	22
at the time	22
sequences and the	22
and development of	22
been developed for	22
so that the	22
the inclusion of	22
of sequences in	22
the central nervous	22
the loss of	22
be associated with	22
of the complex	22
by using a	22
for the analysis	22
of the entire	22
due to a	22
the significance of	22
synthesis of the	22
the sensitivity of	22
of the novel	22
overview of the	22
independent of the	22
s s and	22
the sars coronavirus	22
for detection of	22
indicated that the	22
the sequence data	22
in cell culture	22
in the central	22
the cmv dataset	22
is possible that	22
there are several	22
simulated immunosequencing data	22
hidden markov models	22
are listed in	22
representation of the	22
there have been	22
graphical representations of	22
in our laboratory	22
in the host	22
a protein structure	22
in the analysis	22
to the sequence	22
as a new	22
resulted in the	22
were found in	22
secondary structure and	22
than of the	22
it was also	22
of l oc	22
of more than	22
in the middle	22
of them are	22
relationship between the	22
the ratio of	22
components of the	22
resulting in a	22
the type of	22
of action of	22
characterized by the	22
divided into two	22
the release of	22
and identification of	21
mediated by the	21
to measure the	21
the frequencies of	21
of the b	21
its ability to	21
this means that	21
the understanding of	21
considered as a	21
required for the	21
could also be	21
orders of magnitude	21
positions in the	21
are given in	21
result of the	21
it is well	21
molecular characterization of	21
taking into account	21
the viral rna	21
the prevalence of	21
difference between the	21
studies on the	21
for the identification	21
conformation of the	21
numerical characterization of	21
with the exception	21
as one of	21
sequence and the	21
the two sequences	21
component spectral representation	21
acts as a	21
depend on the	21
native chemical ligation	21
of protein folding	21
to detect the	21
frequency of the	21
of the proposed	21
has been identified	21
sequence accession jx	21
to the n	21
have been studied	21
the phylogenetic analysis	21
a and a	21
the aug codon	21
of a gene	21
for each sequence	21
some of them	21
and have been	21
metagenomic analysis of	21
of the signal	21
been developed to	21
was studied by	21
we have investigated	21
cleavage of the	21
to have a	21
of all possible	21
wang et al	21
solid phase synthesis	21
in spite of	21
version of the	21
sequence and structure	21
point of view	21
has been demonstrated	21
analysis of protein	21
used to study	21
agreement with the	21
the numbers of	21
in the number	21
the differences between	21
of the structural	21
dna and rna	21
they have been	21
the center of	21
it would be	21
terminal part of	21
of the original	21
based on this	21
an overview of	21
proved to be	21
can be divided	20
methods such as	20
is necessary for	20
have developed a	20
from patients with	20
variants of the	20
is a member	20
of viral genome	20
on the number	20
sequence accession cp	20
composition of the	20
it will be	20
is dependent on	20
new method for	20
the in vitro	20
the peptides were	20
amino acids were	20
this study is	20
in the tree	20
in complex with	20
because of its	20
to the cell	20
in the sample	20
in the alignment	20
is known that	20
the attention mechanism	20
on the same	20
given in table	20
sequence has been	20
high level of	20
dna primary sequences	20
have been made	20
a broad range	20
could be a	20
is known about	20
emerging infectious diseases	20
representation of proteins	20
used in a	20
used as an	20
of infectious disease	20
isothermal titration calorimetry	20
size exclusion chromatography	20
to the other	20
are related to	20
d structure of	20
proteins of the	20
of secondary structure	20
from a single	20
structural characterization of	20
in the treatment	20
are expected to	20
method based on	20
coding sequences of	20
as determined by	20
only a few	20
been used for	20
in the dataset	20
in patients with	20
of each of	20
to compute the	20
amino acid is	20
may lead to	20
the abundance of	20
of biological sequences	20
with those of	20
of the query	20
may play a	20
proteins have been	20
a tool for	20
in the early	20
we have previously	20
were prepared by	20
amino acid substitutions	20
pair of sequences	20
assigned to the	20
the concentration of	20
for use in	20
beginning of the	20
we demonstrate that	20
was added to	20
very similar to	20
and the corresponding	20
these results indicate	20
the difference between	20
the scientific community	20
in comparison to	20
a novel method	20
of this protein	20
importance of the	20
orientation of the	20
a small number	20
free sequence comparison	20
that in the	20
at the beginning	20
variability in the	20
the de novo	20
the induction of	20
a length of	20
were obtained by	20
conflict of interest	20
has been the	20
physicochemical properties of	20
into a single	20
a mixture of	20
to identify a	20
in many cases	20
but not in	19
bound to the	19
has led to	19
the increase in	19
translation of the	19
in the evolution	19
to describe the	19
t cell receptor	19
to examine the	19
sequence can be	19
li et al	19
is used for	19
the selection of	19
was based on	19
in aqueous solution	19
the locations of	19
all of these	19
order to investigate	19
of secondary structures	19
the cell membrane	19
mbkm with dmk	19
in our study	19
the auditory display	19
distance between the	19
for the sequence	19
this is an	19
has been studied	19
investigation of the	19
infl uence of	19
sequence alignment and	19
but also in	19
identification and characterization	19
in escherichia coli	19
does not have	19
be useful for	19
the free energy	19
of the results	19
the protein structure	19
the strength of	19
the case for	19
could be detected	19
at room temperature	19
the investigation of	19
data suggest that	19
is available in	19
a model of	19
the characteristics of	19
aspects of similarity	19
on a single	19
defined as the	19
designed and synthesized	19
affi nity for	19
we have recently	19
is caused by	19
new generation of	19
it is likely	19
with the aim	19
to provide a	19
codon usage bias	19
of similarity dissimilarity	19
the replication of	19
to be highly	19
i and ii	19
predicted to be	19
the task of	19
that they have	19
in a given	19
is a new	19
of viral proteins	19
be important for	19
the virus variation	19
as described previously	19
the host cell	19
is used as	19
been reported in	19
to a particular	19
have found that	19
regions in the	19
the first and	19
the first one	19
representations of dna	19
similarity between the	19
hepatitis b virus	19
the exception of	19
believed to be	19
the authors declare	19
in the previous	19
modifi cation of	19
a measure of	19
by solid phase	19
evaluation of the	19
of the genetic	19
the possibility that	19
the a and	19
used to predict	19
a panel of	19
according to their	19
in the order	19
graphical representation and	19
to be an	19
in the sequences	19
by nmr spectroscopy	19
to the high	19
in the public	19
been found in	19
of thousands of	19
and on the	19
in which a	19
were downloaded from	19
of these viruses	19
the genetic code	19
randic et al	19
and they are	19
should be noted	19
are used in	19
different parts of	19
with regard to	19
expressed in the	19
of dna primary	18
for understanding the	18
effects of the	18
a protein is	18
to the formation	18
each of which	18
serves as a	18
of escherichia coli	18
in the virus	18
performance of the	18
was confirmed by	18
is also a	18
light on the	18
has been made	18
we assume that	18
a crucial role	18
a lack of	18
better understand the	18
that the two	18
taxonomy of viruses	18
for min at	18
in the united	18
the protein data	18
been made to	18
evidence for the	18
to show that	18
affected by the	18
the relevance of	18
grid search over	18
are located in	18
fact that the	18
search over hyperparameters	18
the region of	18
in table a	18
to the membrane	18
and in vitro	18
in the latter	18
of the individual	18
development of fip	18
a highly conserved	18
of the spike	18
i and j	18
order to study	18
are presented in	18
recent advances in	18
and the presence	18
in mammalian cells	18
a new generation	18
known as the	18
a secondary structure	18
be useful in	18
the isolation of	18
at the molecular	18
of this family	18
the similarity between	18
terminal region of	18
terms of the	18
the kinetics of	18
the observation that	18
rna secondary structure	18
the immune status	18
and to the	18
a library of	18
dna sequence is	18
amino acid substitution	18
crystal structures of	18
protein coding genes	18
of a variety	18
data on the	18
design of new	18
a protein of	18
world data with	18
genes that are	18
the pathogenesis of	18
be the most	18
in the x	18
is the major	18
can be detected	18
were used as	18
immunodeficiency virus type	18
of which is	18
crucial role in	18
was applied to	18
than those of	18
sequences for the	18
the complete nucleotide	18
a powerful tool	18
the positive class	18
the international committee	18
the input sequences	18
downloaded from the	18
are indicated by	18
binds to the	18
of novel coronavirus	18
within the same	18
of antimicrobial peptides	18
infectious bronchitis virus	18
the advantage of	18
of the standard	18
purpose of this	18
to the c	18
the fraction of	18
convolutional neural network	18
leading to a	18
the list of	18
the last decade	18
of avian influenza	18
demonstrate that the	18
the definition of	18
will be used	18
n is the	18
the usefulness of	18
sequences have been	18
little is known	18
the side chains	18
of the distribution	18
protein sequence and	18
of a particular	18
of dna and	18
in the c	18
with more than	18
is widely used	18
instead of the	18
can see that	18
be due to	18
of the active	18
the coding regions	18
into account the	18
was used in	18
encoded by the	18
have led to	18
the appearance of	18
than in the	18
the folding of	18
in comparison with	18
is applied to	18
histone h coding	18
structures in the	18
mhc class i	18
been identified as	18
number of different	18
these sequences are	18
the template structure	18
of influenza virus	18
were detected in	18
allow us to	18
instances per bag	18
in the nucleus	18
of proteins in	18
web server for	18
of the information	18
it appears that	18
efficiency of the	18
to understand how	18
to our knowledge	18
basis for the	18
were characterized by	18
in a large	18
and at the	18
the p protein	18
of the h	17
relies on the	17
used to calculate	17
such as a	17
a d graphical	17
crucial for the	17
peptides derived from	17
huang et al	17
example of the	17
levels of the	17
this may be	17
evolutionary history of	17
the method is	17
and biological activity	17
focus on the	17
of the world	17
may be the	17
a very high	17
to be important	17
of the genes	17
of viruses in	17
the sequence and	17
diseases such as	17
was performed by	17
deposited in the	17
we examined the	17
on the use	17
to overcome this	17
to ensure that	17
of length n	17
was detected in	17
to inhibit the	17
even in the	17
may have been	17
of nucleic acid	17
then used to	17
found in all	17
sequence of human	17
molecular weight of	17
can be obtained	17
spread of the	17
is not clear	17
in the coding	17
presence of an	17
some of which	17
patterns in the	17
the source of	17
could lead to	17
the specificity of	17
distance between two	17
in the current	17
and protein sequences	17
of the time	17
with each other	17
the full length	17
in vivo and	17
as previously described	17
dynamic light scattering	17
of modern hopfield	17
the bat transcriptome	17
can be a	17
we aim to	17
causative agent of	17
of our method	17
correlation between the	17
goal of this	17
the molecular level	17
in silico sensitivity	17
used to determine	17
have studied the	17
we describe the	17
were performed using	17
completion of the	17
of the orf	17
its interaction with	17
to the target	17
the similarity dissimilarity	17
and structure of	17
assembly of the	17
order to understand	17
is known as	17
necessary for the	17
appeared to be	17
and s s	17
nucleotide sequences of	17
coronavirus associated with	17
c and c	17
are closely related	17
in a number	17
analyses of the	17
performed using the	17
a new approach	17
the capsid protein	17
standard genetic code	17
number of possible	17
terminal domain of	17
deduced amino acid	17
be attributed to	17
in the template	17
and the c	17
to be very	17
to monitor the	17
is expressed in	17
number of the	17
are important for	17
present in a	17
of instances per	17
we compared the	17
in the original	17
interactions between the	17
has shown that	17
there are no	17
proportional to the	17
inspection of the	17
and from the	17
of the graph	17
peptides were synthesized	17
present study was	17
number of protein	17
has been described	17
gene of the	17
on the presence	17
it does not	17
protein with a	17
seen in the	17
genome sequence data	17
we studied the	17
has been applied	17
discovery of novel	17
exon c ds	17
is not known	17
to produce a	17
to one of	17
to search for	17
the x chromosome	17
convolutional neural networks	17
the first aug	17
supported by a	17
sequence similarity to	17
the s s	17
sequence alignment of	17
for the discovery	17
positions of the	17
have investigated the	17
for the production	17
the most frequent	17
of the database	17
with a high	17
been isolated from	17
the standard genetic	17
university of california	17
is a powerful	17
recurrent neural networks	17
of sequences with	16
of the second	16
higher than the	16
sensitivity and specificity	16
on the sequence	16
is well known	16
proteins that are	16
the idea of	16
were determined by	16
there are a	16
allows us to	16
of the method	16
results of this	16
ramsauer et al	16
representation of a	16
of intrinsically disordered	16
to explain the	16
can be identified	16
the most widely	16
of the genomes	16
binding domain of	16
structure and the	16
were isolated from	16
b and c	16
euclidean distance between	16
the start of	16
by use of	16
are thought to	16
downstream of the	16
of the mrna	16
the comparison of	16
the correlation between	16
goal is to	16
a and c	16
genes and genomes	16
lengths of the	16
of the molecule	16
the dynamics of	16
a basis for	16
it possible to	16
the composition of	16
the contribution of	16
we have to	16
we have designed	16
of the sgc	16
section a we	16
only of the	16
of genes and	16
the levenshtein distance	16
at the protein	16
it is interesting	16
starting point for	16
amino acid changes	16
prediction of the	16
in the model	16
dna sequences of	16
represented sequences in	16
novo assembly of	16
that are used	16
origin of the	16
to construct a	16
the cell surface	16
most of them	16
in the world	16
application of the	16
in the mouse	16
at a time	16
to the next	16
of the latter	16
the nucleotide sequences	16
and y chromosomes	16
biologically active peptides	16
result in a	16
multiple instance learning	16
a way that	16
activity in the	16
is that it	16
yet to be	16
during the last	16
may be useful	16
regulation of the	16
of this enzyme	16
to the presence	16
sequences derived from	16
its application to	16
the endoplasmic reticulum	16
a decrease in	16
for the s	16
represented in the	16
de novo design	16
sequences that were	16
for sequence comparison	16
in the identification	16
be useful to	16
in the amino	16
sequences were identified	16
by the following	16
the structures of	16
order to find	16
conclude that the	16
the evaluation of	16
for analysis of	16
this indicates that	16
step in the	16
among the most	16
in the active	16
activity of a	16
over the last	16
of a human	16
in the region	16
the number and	16
are considered to	16
proteins such as	16
are expressed in	16
inhibition of the	16
in relation to	16
existence of a	16
of novel viruses	16
to the human	16
affi nity and	16
the success of	16
the conversion of	16
and with the	16
for identification of	16
not yet been	16
the pattern of	16
was performed in	16
from each of	16
aspects of the	16
the s gene	16
impact on the	16
immunosequencing data with	16
amino acid in	16
the consensus sequence	16
order to determine	16
proven to be	16
real time pcr	16
of the whole	16
analysis showed that	16
extracted from the	16
because they are	16
which have been	16
a phylogenetic analysis	16
studies showed that	16
analysis of similarity	16
is determined by	16
complexity of the	16
h and h	16
choice of the	16
approaches have been	16
is given by	16
of the host	16
methods based on	16
data in the	16
to perform the	16
is to use	16
the alignment methods	16
in all cases	16
the interactions of	16
increasing number of	16
work is to	16
sequence accession jq	16
are required to	16
a web server	16
sites in the	16
genetic diversity of	16
l and l	16
with high accuracy	16
shown in the	16
an attempt to	16
were identified by	16
were observed in	16
xu et ai	16
the fi nal	16
d graphical representations	16
the orf a	15
the site of	15
in the interaction	15
the most recent	15
tools such as	15
be viewed as	15
which is not	15
coding regions of	15
the diversity of	15
composed of a	15
that the n	15
as a single	15
and some of	15
of the coding	15
and standard deviation	15
two sets of	15
was studied in	15
of the national	15
is the same	15
of the natural	15
is a novel	15
linear and cyclic	15
in the membrane	15
revealed the presence	15
on the structure	15
of the input	15
is likely that	15
new class of	15
result of a	15
has been suggested	15
production of a	15
over the past	15
in the rat	15
the human body	15
in the table	15
of this paper	15
the p signal	15
coding sequence of	15
the specifi c	15
have the potential	15
as for the	15
and found that	15
was obtained from	15
we are able	15
the values of	15
we show the	15
stages of the	15
for this reason	15
random dna sequences	15
mechanism by which	15
sequences of different	15
of viral genomes	15
we want to	15
primer and probe	15
standard amino acids	15
means that the	15
at this position	15
and secondary structure	15
and molecular dynamics	15
a multiple sequence	15
acids in the	15
a better understanding	15
tend to be	15
as a template	15
human and animal	15
be detected by	15
of a series	15
an understanding of	15
side chains of	15
analysis revealed that	15
the department of	15
of our approach	15
the types of	15
of the interaction	15
broad spectrum of	15
mouse hepatitis virus	15
a size of	15
the details of	15
of some of	15
of the polyprotein	15
the alignment of	15
protein can be	15
as a reference	15
peptides have been	15
of the receptor	15
molecular evolution of	15
or more sequences	15
other members of	15
obtained by the	15
the last years	15
similarity to the	15
the family of	15
a change in	15
of proteins with	15
the molecular mechanisms	15
to note that	15
international committee on	15
protein fold recognition	15
of the following	15
diversity of the	15
have been successfully	15
a review of	15
the information about	15
according to our	15
of the five	15
a tree decomposition	15
in the l	15
more than of	15
have already been	15
combined with the	15
in silico validation	15
the results show	15
was determined in	15
are difficult to	15
to demonstrate the	15
in both cases	15
phylogenetic analysis based	15
the genetic diversity	15
is critical for	15
identified as the	15
using a combination	15
the distance matrix	15
different aspects of	15
nucleotide and amino	15
contained in the	15
in the laboratory	15
to form the	15
a limited number	15
in the binding	15
the innate immune	15
of phylogenetic trees	15
a critical role	15
the large number	15
of the core	15
similarity dissimilarity of	15
s s s	15
of sequence space	15
that is not	15
shape of the	15
the causative agent	15
are in the	15
we have been	15
is located in	15
strength of the	15
to use the	15
with and without	15
that the p	15
sequences and its	15
of a set	15
to as the	15
the accumulation of	15
conserved in the	15
can be classified	15
a amino acid	15
we observed that	15
value of the	15
the template and	15
with the sequence	15
for the preparation	15
amino acids to	15
noted that the	15
amino acids into	15
lead to a	15
structural studies of	15
of the genomic	15
also in the	15
structure and dynamics	15
the coding sequences	15
we have isolated	15
the sequence length	15
the area of	15
find that the	15
site in the	15
of up to	15
which leads to	15
formed by the	15
viral genome sequences	15
the four bases	15
and the results	15
genomic analysis of	15
plays a key	15
the evolution and	15
effects on the	15
has recently been	15
primary and secondary	15
molecular basis of	15
as a tool	15
a given sequence	15
p signal sequence	15
peptides and their	15
the samples were	15
of the reference	15
can be performed	15
history of the	15
the interactions between	15
challenge stock virus	15
we are now	15
the middle of	15
whole genome sequencing	15
to a single	15
of base pairs	15
in this review	15
members of this	15
the challenge stock	15
the virus in	15
gene expression in	15
in the data	15
to support the	15
the primary structure	15
for treatment of	14
to infer the	14
the genome size	14
processes such as	14
which has a	14
located on the	14
herpes simplex virus	14
types of data	14
in table s	14
the euclidean distance	14
to be in	14
not only in	14
be assigned to	14
caused by a	14
be present in	14
gene and protein	14
the initiation of	14
which in turn	14
of these new	14
protein structure modeling	14
that all the	14
this class of	14
to build a	14
known that the	14
has been widely	14
rise to a	14
results demonstrate that	14
of human immunodeficiency	14
of these genes	14
sequences with a	14
can help to	14
or amino acid	14
and stability of	14
has become a	14
the er membrane	14
protein of the	14
the onset of	14
of the hiv	14
to a specific	14
binding affi nity	14
in the study	14
see that the	14
before and after	14
fcov zu and	14
the infl uence	14
are used as	14
that some of	14
the replacement of	14
have demonstrated that	14
sequences were obtained	14
feature extraction method	14
all the sequences	14
is an essential	14
table shows the	14
total rna was	14
avian infectious bronchitis	14
single amino acid	14
the molecular biology	14
results will be	14
results of our	14
reduction to specific	14
and characterized by	14
of the above	14
an effi cient	14
powerful tool to	14
discovery of new	14
the hepatitis c	14
of in vitro	14
for binding to	14
immune receptor sequences	14
incomplete purifying selection	14
homology to the	14
the possibility to	14
is a good	14
and sequencing of	14
aim is to	14
used to compute	14
of the population	14
the power of	14
involved in a	14
phase synthesis of	14
to control the	14
affinity of the	14
they do not	14
was to determine	14
to contribute to	14
has been a	14
developed a new	14
with reduction to	14
that cannot be	14
they are not	14
to the virus	14
have focused on	14
expressed in a	14
the result is	14
that the protein	14
of the compounds	14
identity with the	14
the most active	14
on taxonomy of	14
proteins based on	14
and phylogenetic analysis	14
the completion of	14
the validity of	14
we focus on	14
in the area	14
impact of the	14
in the input	14
similarity analysis of	14
primer or probe	14
dna sequence and	14
protein folding and	14
the nucleocapsid protein	14
sequence identity with	14
the results are	14
major role in	14
share a common	14
expression of a	14
in the immune	14
that the virus	14
in the pdb	14
synthesized by the	14
shed light on	14
to define the	14
sequence with the	14
positive and negative	14
was designed to	14
the propagation of	14
for immune repertoire	14
of peptides and	14
in the positive	14
to provide the	14
of a virus	14
these peptides are	14
since it is	14
unnatural amino acids	14
and there is	14
from the other	14
modification of the	14
hyperparameters with reduction	14
there are some	14
the input object	14
been used in	14
an increase of	14
we will present	14
for the same	14
as they are	14
the interpretation of	14
the entire genome	14
are one of	14
can be done	14
the intrinsically disordered	14
that the sequence	14
the modulation of	14
the limitations of	14
an effort to	14
number of genes	14
of the sample	14
of these compounds	14
a small fraction	14
of human influenza	14
in the phylogenetic	14
present study we	14
is encoded by	14
a major role	14
expressed sequence tags	14
has its own	14
in figure a	14
and it can	14
previous studies have	14
is not the	14
functional analysis of	14
are needed to	14
during the first	14
of dengue virus	14
what is the	14
up to the	14
increase of the	14
sequences in a	14
that the presence	14
of a small	14
the bloom filter	14
dna sequences with	14
head and tail	14
order to identify	14
the user to	14
rational design of	14
a method for	14
another example of	14
interactions with the	14
the biology of	14
the core of	14
of the experimental	14
h n avian	14
carried out on	14
average length of	14
evidence for a	14
we would like	14
protein intrinsic disorder	14
in this article	14
of molecular biology	14
degree of similarity	14
the update rule	14
comparable to that	14
construction of the	14
aim of the	14
of the available	14
template and target	14
we introduce a	14
here we describe	14
with the number	14
solution structure of	14
sequence and a	14
the history of	14
over hyperparameters with	14
as an alternative	14
have been isolated	14
nucleic acid sequence	14
has been determined	14
the difference in	14
comparative modeling and	14
in this experiment	14
an average of	14
of rna secondary	14
have been introduced	14
the joint model	14
is derived from	14
is located at	14
consisting of the	14
at least in	14
these results are	14
calculated using the	14
it is often	14
the same as	14
the burden test	14
nucleotide sequences were	14
accumulated natural vector	14
is essential to	14
been proposed that	14
the molecular basis	14
the behaviour of	14
one of its	14
are essential for	14
the severe acute	14
the advent of	14
c virus in	14
in the putative	14
the changes in	14
the novel coronavirus	14
contributes to the	14
of sequences that	14
to the reference	14
first aug codon	14
are capable of	14
compared to other	14
by binding to	14
linked to a	14
observed that the	14
protein sequences are	14
committee on taxonomy	14
elements in the	14
this process is	14
in most of	14
carried out to	14
of the primary	14
of which were	14
presence or absence	14
protein has been	14
were treated with	14
that this is	14
of the biological	14
are available for	13
gives rise to	13
in the different	13
interest in the	13