trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
in patients with	152
of the ras	144
of ang ii	115
of the renin	97
the use of	95
angiotensin converting enzyme	91
angiotensin ii type	87
as well as	80
severe acute respiratory	79
acute respiratory syndrome	78
angiotensin ii receptor	71
the role of	70
of angiotensin ii	70
ii type receptor	69
patients with covid	68
been shown to	65
the expression of	64
in the brain	61
the development of	61
in addition to	58
it has been	55
of the ace	53
vascular smooth muscle	52
activation of the	51
the risk of	49
smooth muscle cells	49
acute respiratory distress	48
of at r	48
respiratory distress syndrome	47
is associated with	47
in response to	46
the effects of	44
the plasma membrane	44
converting enzyme inhibitors	44
of ace in	43
the at r	43
the presence of	42
respiratory syndrome coronavirus	42
has been shown	42
the at receptor	41
renin angiotensin system	39
angiotensin system in	38
role of the	38
due to the	37
angiotensin receptor blockers	37
components of the	36
loss of ace	36
converting enzyme in	36
role in the	35
the angiotensin ii	35
and angiotensin ii	35
one of the	33
of aceis arbs	33
at r and	32
to ang ii	32
of patients with	32
of ras inhibitors	32
the treatment of	32
the pathogenesis of	32
ang ii and	32
the progression of	31
the effect of	31
the regulation of	31
in the heart	30
of the angiotensin	30
reactive oxygen species	30
ace inhibitors and	29
in the lung	29
and ang ii	29
an increase in	29
the activation of	28
expression of the	28
of angiotensin converting	28
inhibitors and angiotensin	28
the brain ras	28
involved in the	28
the ace gene	27
the mas receptor	27
expression of ace	27
that ang ii	27
use of aceis	27
with the use	27
in order to	27
of ace and	26
and at r	26
by angiotensin ii	26
in the kidney	26
the ace ang	26
the discovery of	26
induced lung injury	26
angiotensin system and	25
the level of	25
addition to the	25
an important role	25
of the sars	25
on the other	25
a number of	25
a variety of	25
angiotensin ii in	24
enzyme inhibitors and	24
the ras in	24
ii receptor blockers	24
the release of	24
effect of angiotensin	24
aceis and arbs	24
of severe acute	24
associated with the	23
spontaneously hypertensive rats	23
in cardiovascular disease	23
by ang ii	23
transforming growth factor	23
effects of the	23
there is a	23
the production of	23
structure of the	23
based on the	23
a role in	23
the ang ii	23
clinical characteristics of	23
of ang i	23
to the plasma	23
activated protein kinase	22
risk of mortality	22
central nervous system	22
severe critical outcomes	22
has been reported	22
a crucial role	22
the classical ras	22
of the at	22
acei arb users	22
role of angiotensin	22
receptor for sars	22
ras in the	21
important role in	21
role of ace	21
the other hand	21
growth factor receptor	21
in the development	21
acute lung injury	21
in the rat	21
have been shown	21
the spike protein	20
tumor necrosis factor	20
epidermal growth factor	20
use of an	20
ace and ace	20
infected with sars	20
effects of ang	20
of blood pressure	20
in the ras	20
ang i and	20
have shown that	20
ang ii to	20
the absence of	20
of ace inhibitors	20
in the pathogenesis	20
ang ii in	20
of captopril on	20
are associated with	19
the activity of	19
the renin angiotensin	19
in animal models	19
shown to be	19
ang ii is	19
angiotensin type receptor	19
in the early	19
the number of	19
of the brain	19
with coronavirus disease	19
differences in the	19
in this study	19
as a result	19
sodium and water	19
patients with hypertension	19
converting enzyme inhibitor	18
in the treatment	18
blood pressure in	18
compared with the	18
an acei arb	18
such as the	18
of gut microbiota	18
at and at	18
was associated with	18
of an acei	18
systematic review and	18
regulator of the	18
the central nervous	18
the existence of	18
compared to the	18
the gastrointestinal tract	18
review and meta	18
ace is a	18
of severe critical	18
ang ii at	17
risk of severe	17
and angiotensin receptor	17
blood pressure and	17
lung tumor tissue	17
the formation of	17
the ras and	17
the ras system	17
and the renin	17
in the ace	17
chronic kidney disease	17
studies that provided	17
is a key	17
ii in the	17
from ang ii	17
patients infected with	17
analysis of the	17
found to be	16
related to the	16
an angiotensin ii	16
patients with coronavirus	16
the cardiovascular system	16
patients with sars	16
a reduction in	16
be associated with	16
converting enzyme is	16
in heart failure	16
angiotensin i to	16
and activation of	16
severe critical illness	16
regulation of the	16
receptor blockers on	16
that provided adjusted	16
converting enzyme and	16
in the lungs	16
and oxidative stress	16
sky and sky	16
contributes to the	16
with novel coronavirus	16
the ras is	16
converting enzyme inhibition	16
acts as a	16
ace expression in	16
ace in the	16
acute kidney injury	15
found in the	15
of angiotensin i	15
in blood pressure	15
vascular endothelial growth	15
expressed in the	15
the action of	15
endothelial growth factor	15
oxidative stress in	15
and cardiovascular disease	15
to angiotensin ii	15
system in the	15
inflammation and fibrosis	15
in the human	15
a systematic review	15
i to angiotensin	15
increased expression of	15
in angiotensin ii	15
which in turn	15
of ras l	15
of the protective	15
the dm group	15
effects of angiotensin	15
downregulation of ace	15
at r in	15
of podocyte injury	15
be involved in	15
the generation of	15
in vitro and	15
is mediated by	15
functional receptor for	15
use of ras	15
the importance of	15
the novel coronavirus	15
been reported to	14
ang ii levels	14
studies have shown	14
association between the	14
in a mouse	14
has been suggested	14
risk factors for	14
changes in the	14
in spontaneously hypertensive	14
the loss of	14
increased risk of	14
angiotensin ii and	14
of these drugs	14
mas receptor axis	14
in the regulation	14
associated with a	14
activity of the	14
of diabetic nephropathy	14
also known as	14
i and ang	14
stimulation of the	14
developing severe critical	14
and risk of	14
in diabetic nephropathy	14
the gut microbiota	14
individuals with diabetes	14
of developing severe	14
is involved in	14
in vascular smooth	14
a result of	14
patients with diabetes	14
for the treatment	14
normal lung tissue	14
axis of the	14
plays an important	13
in the absence	13
mouse model of	13
there is no	13
and in vivo	13
derivatives of ras	13
the heart and	13
cardiovascular and renal	13
the pathophysiology of	13
in the dm	13
a mouse model	13
the ras pathway	13
inhibition of the	13
of the ang	13
may contribute to	13
of ace is	13
effects of ace	13
ii receptor antagonist	13
expression in the	13
angiotensin ii receptors	13
and at receptors	13
the context of	13
the ace axis	13
smooth muscle cell	13
in the context	13
vascular endothelial cells	13
of the glomerular	13
more likely to	13
r and at	13
endoplasmic reticulum stress	13
in the central	13
the control of	13
ace ang ii	13
with ace inhibitors	13
according to the	13
vitro and in	13
risk of cancer	13
hypertension and diabetes	13
aceis arbs in	13
arm of ras	13
blood pressure regulation	13
aldosterone system inhibitors	13
and heart failure	13
alveolar epithelial cells	13
the active site	13
cells in the	13
zhang et al	13
pneumonia in wuhan	12
the dm ab	12
may lead to	12
and treatment of	12
is known to	12
of ras in	12
in sars coronavirus	12
levels of ang	12
ace inhibitors or	12
recombinant human ace	12
high blood pressure	12
dm ab group	12
of patients infected	12
to the non	12
retrospective cohort study	12
in a rat	12
formation of ang	12
is an important	12
the severity of	12
ang ii can	12
the conversion of	12
crucial role of	12
a rat model	12
the ability of	12
production of ang	12
as a receptor	12
the united states	12
have been identified	12
the association between	12
was shown to	12
effects of ras	12
blockade of the	12
hospitalized patients with	12
play a role	11
arm of the	11
that ace is	11
it is not	11
of inflammatory cytokines	11
of the yeast	11
gender differences in	11
view of the	11
highly expressed in	11
an ace inhibitor	11
and blood pressure	11
and severity of	11
been identified as	11
expression of at	11
in terms of	11
such as hypertension	11
the immune system	11
its role in	11
of ace expression	11
with type diabetes	11
at receptors in	11
a central role	11
between the use	11
and at receptor	11
has not been	11
in the elderly	11
to determine the	11
is an essential	11
receptor for the	11
inhibitors and arbs	11
inhibitors of the	11
of coronavirus disease	11
negative regulator of	11
evidence for a	11
a key role	11
ace expression and	11
showed that the	11
for multiple comparisons	11
east respiratory syndrome	11
nih t cells	11
podocyte injury in	11
conversion of ang	11
arbs in covid	11
from patients with	11
severe critical disease	11
some of the	11
has been demonstrated	11
sex differences in	11
the function of	11
receptors in the	11
involvement of the	11
enzyme in the	11
use of angiotensin	11
were used to	11
appears to be	11
converting enzyme activity	11
of senescent cells	11
i to ang	11
at r is	11
glomerular basement membrane	11
a retrospective cohort	11
of the virus	11
may be the	11
among patients with	11
for treatment of	11
has also been	11
beneficial effects of	11
in the gut	11
cov and sars	11
the degree of	10
ace and the	10
to be a	10
protective role of	10
actions of ang	10
the ratio of	10
most of the	10
to the development	10
as a consequence	10
in diabetic rats	10
regulator of heart	10
which can be	10
is expressed in	10
angiotensin system inhibitors	10
and progression of	10
the abundance of	10
patients with severe	10
endothelial dysfunction in	10
binds to the	10
lower risk of	10
may also be	10
protective arm of	10
to be the	10
risk of covid	10
the levels of	10
from ang i	10
with regard to	10
of the disease	10
is critical for	10
contribute to the	10
and er stress	10
and endothelial dysfunction	10
levels of ace	10
activity in the	10
in the presence	10
at the same	10
distribution of ace	10
there is evidence	10
amino acid transporter	10
receptor blockers and	10
oxidative stress and	10
of the mas	10
of the classical	10
to the virus	10
the functional receptor	10
identified as a	10
of ras proteins	10
morbidity and mortality	10
the ace receptor	10
have been reported	10
be able to	10
has been identified	10
the three groups	10
the results of	10
of the two	10
higher levels of	10
of angiotensinconverting enzyme	10
ang ii by	10
plasma renin activity	10
in acute respiratory	10
middle east respiratory	10
angiotensin ii induces	10
and the risk	10
coronary artery disease	10
protective effect of	10
should not be	10
the structure of	10
animal models of	10
stimulation of at	10
mediated by at	10
at r expression	10
of novel coronavirus	10
in hypertensive patients	10
effect of the	10
ang ii could	10
of the gut	10
responsible for the	10
the angiotensin converting	10
well as the	10
at receptor blockers	10
the impact of	10
converting enzyme gene	10
the ace angiotensin	10
the combination of	10
that can be	10
induced vsmc senescence	9
in line with	9
clinical outcomes in	9
lead to a	9
a disintegrin and	9
exposure time to	9
diabetes mellitus and	9
activation of at	9
with lower odds	9
the synthesis of	9
was observed in	9
in cardiovascular and	9
acute lung failure	9
in individuals with	9
central role in	9
significant association with	9
of oxidative stress	9
nitric oxide synthase	9
is essential for	9
with respect to	9
domain of ace	9
activation of prorenin	9
the amount of	9
and risk factors	9
for severe critical	9
human homolog of	9
renal injury in	9
risk of developing	9
ectodomain shedding of	9
gut microbiota and	9
generation of ang	9
is required for	9
pi k akt	9
epicardial adipose tissue	9
the prevention of	9
in orx mice	9
was found to	9
key role in	9
ras and the	9
a protective role	9
physiology and pathophysiology	9
ii receptor subtypes	9
targeted to the	9
of brain ras	9
with the ace	9
may be more	9
been identified in	9
in the plasma	9
treatment of covid	9
converts angiotensin i	9
spike protein of	9
the severe acute	9
to that of	9
effect of captopril	9
decreased expression of	9
in acute lung	9
cardiovascular disease and	9
expression as a	9
in experimental models	9
might be a	9
hospitalized with covid	9
in these patients	9
found that the	9
physiological and pathological	9
shedding of the	9
and function of	9
the surface of	9
insights into the	9
system inhibitors in	9
the course of	9
ras has been	9
proteolytic cleavage of	9
have demonstrated that	9
part of the	9
clinical course and	9
amino acid residues	9
as a potential	9
as a novel	9
to play a	9
epithelial cells and	9
treatment of hypertension	9
is important to	9
in the cardiovascular	9
of heart function	9
difference in the	9
are involved in	9
be due to	9
is also a	9
essential regulator of	9
in early dn	9
in endothelial cells	9
in normal lung	9
a critical role	9
the g protein	9
amino acids in	9
known to be	9
leads to the	9
the hypothesis that	9
ace has been	9
gut microbiota in	9
signal transduction pathways	9
an essential regulator	9
novel coronavirus in	9
the control group	9
of recombinant human	9
of a novel	9
in lung tumor	9
no significant difference	9
in the kidneys	8
the transmembrane domain	8
which is a	8
of lung injury	8
of at receptors	8
ang ii infusion	8
a novel therapeutic	8
at r has	8
of orx mice	8
between the two	8
for sars coronavirus	8
mechanism by which	8
ang i to	8
high level of	8
many of the	8
and functional expression	8
focal segmental glomerulosclerosis	8
rat model of	8
receptor tyrosine kinases	8
the general population	8
the glomerular filtration	8
it was found	8
thought to be	8
of the protein	8
inhibitors and at	8
there may be	8
of sars coronavirus	8
lung injury in	8
mrna expression of	8
it is reasonable	8
and lung injury	8
diseases such as	8
been reported that	8
to produce ang	8
protein of sars	8
blood pressure elevation	8
to have a	8
cell lung cancer	8
is an endogenous	8
length human ace	8
conflicts of interest	8
reported a higher	8
ace gene expression	8
effects in the	8
it may be	8
on the potential	8
in type diabetes	8
the lack of	8
time to the	8
linked to viral	8
impact on the	8
protein expression of	8
for mortality of	8
leading to the	8
shown to have	8
loss of angiotensin	8
the ras by	8
functional expression as	8
course and risk	8
the ras are	8
outcomes in covid	8
appear to be	8
in the renin	8
compared with that	8
were found to	8
for ang ii	8
for the sars	8
factors for mortality	8
of hypertension and	8
the protein expression	8
intensive care units	8
hypertensive patients with	8
to the ras	8
of cardiovascular disease	8
with at r	8
in a variety	8
ace as a	8
ang ii receptor	8
of the severe	8
adult inpatients with	8
the circulating ras	8
induced by angiotensin	8
mortality of adult	8
in the risk	8
in rat brain	8
as a therapeutic	8
the protective arm	8
is reasonable to	8
sympathetic nervous system	8
the mechanism of	8
our understanding of	8
conflict of interest	8
in the covid	8
cloning and functional	8
syndrome coronavirus infection	8
understanding of the	8
at the c	8
crucial role in	8
podocyte injury and	8
may play a	8
at r blockers	8
coronavirus disease in	8
of trabecular bone	8
the coronavirus disease	8
after myocardial infarction	8
the balance between	8
a higher crude	8
outcomes of patients	8
and cardiac dysfunction	8
the c domain	8
was reported to	8
is believed to	8
both ace and	8
the observation that	8
in subjects with	8
compared to those	8
heart failure and	8
was used for	8
been demonstrated to	8
ace is the	8
angiotensin ii at	8
ang ii into	8
by ace inhibitors	8
fluid and electrolyte	8
with the control	8
demonstrated that the	8
patients with chronic	8
type receptor blockade	8
of vascular smooth	8
db db mice	8
of the local	8
associated with increased	8
increase in ace	8
and the at	8
by at r	8
mrna and protein	8
of this article	8
of adult inpatients	8
arms of ras	8
coupled receptor mas	8
genes involved in	8
of neutral endopeptidase	8
and inhibition of	8
infected with novel	8
function of the	8
been suggested that	8
a novel angiotensin	8
ang ii formation	8
at a r	8
the pi k	8
a human homolog	8
in the pathophysiology	8
robotic assisted surgery	8
the reninangiotensin system	8
has been found	8
human coronavirus nl	8
a consequence of	8
a receptor for	8
as compared to	8
basis for the	8
outcomes in patients	8
roles in the	8
t cells were	8
inpatients with covid	8
are thought to	8
prevention and treatment	8
of severe covid	8
of diabetes and	8
role of ang	8
is regulated by	8
the lung tumor	8
due to a	8
provided adjusted estimates	8
of the kidney	8
protein kinase c	8
suggesting that the	8
mortality in covid	8
no conflict of	8
it is important	8
together with the	8
lung tissue and	8
expression of angiotensin	8
hxt and hxt	8
the degradation of	8
patients with novel	8
on the ras	8
of ace ace	8
pulmonary arterial hypertension	8
a total of	8
more severe disease	7
by inhibiting the	7
enzyme protects from	7
inhibition and angiotensin	7
has been proposed	7
use of arbs	7
of ace expressing	7
critical role in	7
protein kinase b	7
role in maintaining	7
diabetes infected with	7
disease in china	7
been linked to	7
pathways of the	7
of nitric oxide	7
pdr and pdr	7
on the epithelial	7
an animal model	7
that in the	7
supplementary table s	7
the angiotensin type	7
converting enzyme protects	7
patients hospitalized with	7
properties of the	7
the insulin receptor	7
converting enzyme angiotensin	7
the addition of	7
and ace in	7
type receptor and	7
that patients with	7
features of patients	7
is increased in	7
structural basis for	7
to lead to	7
high levels of	7
is thought to	7
in the cell	7
novel coronavirus pneumonia	7
in the case	7
significant decrease in	7
of the plasma	7
the stimulation of	7
is highly expressed	7
i converting enzyme	7
is possible that	7
ace mrna expression	7
of angiotensin receptor	7
lower odds of	7
attenuates the progression	7
at r or	7
ace and tmprss	7
linked mental retardation	7
on blood pressure	7
development of glomerulosclerosis	7
or angiotensin receptor	7
on cardiac angiotensin	7
reported that the	7
of the proteins	7
inhibitors in patients	7
the collecting duct	7
as a captopril	7
and diabetes mellitus	7
response to ang	7
of which are	7
ace activity in	7
the possibility of	7
bronchial epithelial cells	7
blockers on cardiac	7
a model of	7
been found that	7
in the renal	7
of viral infection	7
through at r	7
crystal structure of	7
with severe acute	7
risk factor for	7
as a sars	7
ang i into	7
a l p	7
treatment with ace	7
included in the	7
of ras components	7
heart and kidney	7
ace activity and	7
and mortality in	7
the subfornical organ	7
in vitro studies	7
a negative regulator	7
such as diabetes	7
circulating ang ii	7
induced by angii	7
the occurrence of	7
of the genes	7
type receptor in	7
r o o	7
in lung cancer	7
used for the	7
a lower risk	7
animal model of	7
lipid accumulation in	7
which could be	7
been reported in	7
as the receptor	7
in the vasculature	7
amino acid linker	7
the ace ace	7
the n domain	7
the induction of	7
plays a role	7
effect of ras	7
the brain and	7
be attributed to	7
the cleavage of	7
with a high	7
for the prevention	7
activity of ace	7
the permeability of	7
ang ii production	7
domain of sace	7
we propose that	7
members of the	7
ace is also	7
health and disease	7
bone mineral density	7
blockers and the	7
the ras has	7
it would be	7
integral membrane protein	7
by the ace	7
versions of ras	7
have a higher	7
ace expression is	7
is likely to	7
potential therapeutic target	7
on the x	7
cell proliferation and	7
enzyme is an	7
implicated in the	7
advanced glycation end	7
and in the	7
by blockade of	7
the kinin system	7
p ink a	7
j o u	7
type alveolar cells	7
novel coronavirus from	7
may have a	7
world health organization	7
effects of at	7
via the at	7
ace and ang	7
development and progression	7
death in patients	7
and clinical implications	7
r n a	7
integrity of the	7
activation of ras	7
of the c	7
risk of death	7
p r o	7
and mas receptors	7
in association with	7
molecular mechanisms and	7
need to be	7
in the liver	7
actions of angiotensin	7
the host cell	7
seems to be	7
the virus and	7
the authors declare	7
there are two	7
differences in immune	7
lung epithelial cells	7
by the spike	7
therapeutic target for	7
of ras are	7
fusion proteins were	7
experimental and clinical	7
loss of the	7
angiotensin system blockade	7
the actions of	7
and outcomes of	7
it is possible	7
which is the	7
and characterization of	7
gene expression of	7
and clinical studies	7
both of which	7
in hospitalized patients	7
ii at receptor	7
the same time	7
ii receptor blocker	7
the rate of	7
tissue injury and	7
to study the	7
blood flow to	7
significantly associated with	7
a reduction of	7
ii production and	7
was used to	7
p r e	7
experimental models of	7
innate and adaptive	7
enzyme is a	7
on trabecular bone	7
patients with type	7
within the brain	7
play an important	7
with essential hypertension	7
we found that	7
a decrease in	7
upregulation of angiotensin	7
receptor in the	7
l p r	7
has recently been	7
n a l	7
blood flow and	7
regulation of ace	7
of transforming growth	7
the molecular mechanisms	7
glomerular filtration barrier	7
compared to non	7
with diabetes infected	7
enzyme inhibition and	7
o o f	7
of ras blockade	7
was involved in	7
not yet been	7
of the reninangiotensin	7
of the novel	7
lung injury and	7
disease severity in	7
in chronic kidney	7
blockade of angiotensin	7
human ace in	7
has been described	7
receptor of sars	7
and has been	7
a review of	7
clinical features of	7
the components of	7
have not been	7
release of vasopressin	7
and inflammation in	7
might lead to	7
the outcome of	7
o u r	7
ang ii also	7
coronavirus spike protein	7
suggested that the	7
senescence and sasp	7
severity of covid	7
u r n	7
ace expressing cells	7
characteristics of coronavirus	7
and neprilysin in	7
and safety of	7
is a critical	7
in the gastrointestinal	6
rats angiotensin ii	6
the intrarenal renin	6
progression of diabetic	6
of lung cancer	6
angiotensin ii production	6
the application of	6
inhibitors angiotensin receptor	6
hypertensive rats angiotensin	6
in vascular endothelial	6
the gene expression	6
release of inflammatory	6
of the three	6
ii and ang	6
homolog of angiotensin	6
and angiotensin converting	6
of hepatic fibrosis	6
mechanisms and potential	6
and potential therapeutic	6
innate immune response	6
the inflammatory response	6
mas receptor in	6
crude mortality rate	6
and clinical outcomes	6
to those of	6
identified in the	6
renin receptor in	6
adjusted mortality estimates	6
could be a	6
to note that	6
expression in rat	6
to evaluate the	6
lung injury by	6
shown to inhibit	6
effect of ace	6
ras l derivatives	6
it is of	6
in recent years	6
patients linked to	6
of the most	6
domain complexed with	6
the mrna expression	6
subjects with diabetes	6
was identified as	6
are shown in	6
remains to be	6
of type diabetes	6
reduced risk of	6
interaction of the	6
podocytes cultured in	6
loads and lung	6
association with the	6
in regulating the	6
may result in	6
a functional receptor	6
dose of captopril	6
the fusion proteins	6
to ace inhibitors	6
expression of renin	6
angiotensin system blockers	6
is not the	6
and its expression	6
ace activity is	6
is responsible for	6
the systemic circulation	6
a first step	6
of ras wt	6
of neurogenic hypertension	6
regulated ectodomain shedding	6
in mice with	6
and biochemical indexes	6
have a more	6
system inhibitors and	6
may be associated	6
discovery of renin	6
between acei arb	6
the distribution of	6
binding domain complexed	6
degradation of ang	6
ras to the	6
the onset of	6
plays a crucial	6
correction for multiple	6
the recognition of	6
clinical and biochemical	6
effects on the	6
to viral loads	6
effects of captopril	6
type diabetic mice	6
and apoptosis in	6
to elucidate the	6
into intensive care	6
under the control	6
surface of the	6
of cardiac injury	6
via at r	6
the lungs of	6
this article is	6
the creative commons	6
in type diabetic	6
large number of	6
of ace receptor	6
first step in	6
enzyme inhibitors angiotensin	6
to high glucose	6
and water absorption	6
of ace protein	6
the majority of	6
the cell membrane	6
tissue growth factor	6
hypoxic pulmonary vasoconstriction	6
tissue distribution of	6
amino acid linkers	6
infected patients linked	6
is prevented by	6
of renin in	6
in states of	6
the rostral ventrolateral	6
reduction in the	6
targeted derivatives of	6
present in the	6
cleavage of the	6
this is the	6
by at receptors	6
ras wt and	6
angii and ang	6
a combination of	6
in rats with	6
ncov infected patients	6
in coronavirus disease	6
is supported by	6
exclusively hypertensive patients	6
the secretion of	6
ang iii is	6
be explained by	6
to the ace	6
cellular responses to	6
and protein expression	6
by the sars	6
transforming activity of	6
receptor binding domain	6
studies that reported	6
vascular senescence and	6
viral entry into	6
of the human	6
the disruption of	6
and its role	6
hypertrophy and fibrosis	6
amino acid transporters	6
the beneficial effects	6
ace as the	6
a role for	6
in combination with	6
in the late	6
c domain of	6
pulmonary vasoconstriction in	6
a state of	6
use of renin	6
be induced by	6
ang ii concentration	6
viral loads and	6
and ulcerative colitis	6
animal models and	6
severe acute lung	6
biochemical indexes from	6
a more severe	6
ace ace balance	6
proven to be	6
there is an	6
as an integral	6
the evolution of	6
understanding sars pathogenesis	6
expressed at a	6
into host cells	6
expression and activity	6
reduced expression of	6
from the membrane	6
expression of cd	6
results in a	6
the structure and	6
protects from severe	6
diseases associated with	6
resulting in a	6
addition to its	6
and renal disease	6
therapeutic potential of	6
identified as the	6
this study was	6
and death in	6
enzyme in human	6
acei and arb	6
to severe acute	6
step in understanding	6
monocyte chemoattractant protein	6
from severe acute	6
integral membrane versions	6
type diabetes and	6
an integral membrane	6
ras is a	6
human bronchial epithelial	6
number of studies	6
of ace by	6
plasma levels of	6
the phosphorylation of	6
was discovered in	6
been demonstrated in	6
cultured in vitro	6
interest in the	6
cells of the	6
role for the	6
have been developed	6
connective tissue growth	6
caused by the	6
no conflicts of	6
of the components	6
of protein kinase	6
has not yet	6
member of the	6
in the group	6
the cell surface	6
i and ii	6
mrna expressions of	6
serve as a	6
nephrin and podocin	6
the increase in	6
may be an	6
mediated stimulation of	6
unfolded protein response	6
ace and at	6
system blockers and	6
patients treated with	6
membrane versions of	6
terminus of ras	6
ii and at	6
of components of	6
is characterized by	6
the glomerular basement	6
similar to the	6
angiotensin system the	6
given that ace	6
effects of losartan	6
of cellular senescence	6
role in cardiovascular	6
induced acute lung	6
of prr in	6
that there was	6
diabetic nephropathy and	6
renal disease and	6
at receptor signaling	6
foot process effacement	6
likely to have	6
discovery of ace	6
the incidence of	6
expression of ras	6
lead to the	6
severity and mortality	6
likely to die	6
in complex with	6
vascular inflammation and	6
the mrna expressions	6
mediated by the	6
treatment with captopril	6
mediates regulated ectodomain	6
increased susceptibility to	6
is seen in	6
associated with lower	6
level of expression	6
of a local	6
at risk of	6
in health and	6
podocyte loss in	6
development of the	6
severity in covid	6
as seen in	6
more severe covid	6
vulnerability to sars	6
the receptor for	6
roles of the	6
have also been	6
gene expression in	6
prorenin receptor in	6
the local ras	6
an attempt to	6
diabetic renal injury	6
that there is	6
of reninangiotensin system	6
it is also	6
of ras to	6
the changes in	6
ras have been	6
is a potent	6
renin prorenin receptor	6
a wide variety	6
ace g a	6
the sars coronavirus	6
in understanding sars	6
increase in the	6
imbalance in the	6
critical for the	6
essential role in	6
in the at	6
acute myocardial infarction	6
damage caused by	6
illness with the	6
the accumulation of	6
ang ii was	6
it should be	6
at high risk	6
critically ill patients	6
studies were from	6
provided adjusted mortality	6
ras and raf	6
their ability to	6
cleavage of ang	6
beneficial effect of	6
associated secretory phenotype	6
all of which	6
that of the	6
is due to	6
in ang ii	6
and the ras	6
of the first	6
a recent study	6
ras components in	6
and p mapk	6
on the cell	6
suggest that the	6
binding to the	6
system and the	6
inhibitors or arbs	6
in the c	6
the main effector	6
a high level	6
inflammatory and anti	6
the potential of	6
neutral amino acids	6
wide variety of	6
the brain of	6
of ras genes	6
in maintaining the	6
is a major	6
of the cov	6
of extracellular matrix	6
and vascular smooth	6
to the risk	6
be noted that	6
aceis arbs and	6
influence of angiotensin	6
pivotal role of	6
of proinflammatory cytokines	6
for cardiovascular disease	6
crude rate for	6
intrarenal ras activation	6
of the rat	6
of the lung	6
deletion of the	6
development of dn	6
this is a	6
association with lower	6
and adaptive immune	6
in contrast to	6
receptor recognition by	6
that activation of	6
signaling in the	6
with severe covid	6
rostral ventrolateral medulla	6
patients with advanced	6
angii at r	6
the ace and	6
a target for	6
or treatment with	6
was found that	6
the interaction between	6
contributing to the	6
of mas receptor	6
results in the	6
ace gene and	5
mortality and severity	5
therapeutic targets for	5
nonproteolytic activation of	5
neurons in the	5
the in vivo	5
the blood pressure	5
when compared to	5
renin and prorenin	5
explanation for this	5
lung function and	5
that the ace	5
administration of the	5
may serve as	5
plays a key	5
as hypertension and	5
for the g	5
ace mrna and	5
ace functions as	5
has emerged as	5
and the development	5
and water retention	5
of at receptor	5
the efficacy of	5
to the nucleus	5
the map kinase	5
which may be	5
in china clinical	5
within the lungs	5
mutations in the	5
may not have	5
lung cancer risk	5
in disease severity	5
kidney injury in	5
no increased risk	5
of death in	5
infarction by blockade	5
that may be	5
kriz et al	5
in support of	5
that reported a	5
have been proposed	5
an important factor	5
structure of sars	5
tumor cell death	5
effects on blood	5
localized to the	5
this results in	5
ras fusion proteins	5
human angiotensinconverting enzyme	5
there have been	5
angiotensin peptides and	5
disruption of the	5
at r axis	5
suggests that the	5
outcomes among patients	5
increases ace expression	5
use of acei	5
in accordance with	5
characteristics of patients	5
and blood vessels	5
to those with	5
relationship between the	5
is found in	5
level in the	5
ras system in	5
smad signal pathway	5
for the recognition	5
is sufficient to	5
growth factor beta	5
impact of the	5
a protective effect	5
to an increase	5
the case of	5
of hxt and	5
at the end	5
novel target for	5
at receptor and	5
acting on the	5
acei arb was	5
cardiac hypertrophy and	5
in an attempt	5
microbiota in the	5
areas of the	5
in diabetes mellitus	5
expected to be	5
ace and adam	5
endogenous ligand for	5
to assess the	5
be responsible for	5
in the acute	5
angiotensin ii levels	5
to the activation	5
are responsible for	5
studies of sars	5
there has been	5
pulmonary neuroendocrine cells	5
pooled analysis of	5
taken into account	5
activities and is	5
in diabetic kidney	5
mrna expression in	5
similar to that	5
to form a	5
the apical membrane	5
observed in the	5
of the enzyme	5
the nucleus tractus	5
and may be	5
there was no	5
is likely that	5
with hypertension hospitalized	5
a member of	5
of glomerulosclerosis in	5
ii type a	5
in patients taking	5
preserved ejection fraction	5
of the membrane	5
cells to the	5
at r by	5
in view of	5
metabolism of ang	5
of a large	5
a positive feedback	5
is clear that	5
and the expression	5
and insulin resistance	5
mortality in hospitalized	5
cardiac injury with	5
the exposure time	5
myocardial infarction by	5
disease and ulcerative	5
receptor and the	5
in human lung	5
converting enzyme after	5
an essential role	5
the fact that	5
under diabetic conditions	5
with hypertension and	5
expression of genes	5
ii into ang	5
delivery to the	5
the innate immune	5
of arbs and	5
a therapeutic target	5
be used for	5
considered to be	5
ii is a	5
ace inhibitors are	5
of the dm	5
might have a	5
the hxt gene	5
significantly reduced the	5
of ras activation	5
vaccine and olmesartan	5
structure and function	5
to the regulation	5
association of angiotensin	5
case fatality rate	5
learning and memory	5
it is unclear	5
a potential therapeutic	5
and pulmonary hypertension	5
of mortality and	5
were measured by	5
the spike glycoprotein	5
ace shedding in	5
for coronavirus disease	5
the sympathetic nervous	5
a range of	5
in the prevention	5
it is likely	5
components of ras	5
the early stage	5
high dose of	5
ace levels in	5
in the three	5
of vascular endothelial	5
is the most	5
reported in the	5
inhibitors in covid	5
enzymes and receptors	5
oxygen species in	5
ang ii are	5
the interaction of	5
in the mouse	5
spontaneously hypertensive rat	5
circulating angiogenic cells	5
new class of	5
ace null mice	5
coward et al	5
reduction in ace	5
local ras systems	5
in the general	5
systemic ang ii	5
by ace to	5
ii and the	5
of epidermal growth	5
illness from covid	5
of hypertension in	5
in kidney disease	5
systolic blood pressure	5
the ras axis	5
system blockade on	5
analysis based on	5
tissue and lung	5
ace and renin	5
association of cardiac	5
a novel coronavirus	5
of a single	5
i d polymorphism	5
coronavirus in wuhan	5
was supported by	5
of diabetic complications	5
to ang i	5
to reduce the	5
forming enzymes and	5
em structure of	5
not be used	5
patients with pulmonary	5
of inflammatory cells	5
epithelial cells of	5
on the role	5
for cardiovascular diseases	5
to the increased	5
responses to renin	5
level of ang	5
antithrombotic effect of	5
the ace inhibitor	5
chronic hepatitis c	5
hepatitis b virus	5
is induced by	5
activity may be	5
the modulation of	5
control of the	5
the association of	5
stress in the	5
in immune responses	5
ang ii generation	5
binds to ace	5
on portal pressure	5
receptor blockers with	5
action of angiotensin	5
the potential to	5
rate for severe	5
disease and hypertension	5
associated with covid	5
characterization of a	5
the integrity of	5
level of ace	5
expression in human	5
nicotinamide adenine dinucleotide	5
which cells were	5
users and non	5
intracellular ang ii	5
in the pvn	5
protein expression in	5
it is clear	5
of amino acids	5
is no evidence	5
proteins such as	5
of angiotensin receptors	5
and cellular responses	5
leads to a	5
lung tumor cells	5
characteristics and outcomes	5
angiotensin ii angiotensin	5
is capable of	5
differential expression of	5
been associated with	5
studies showed that	5
seem to be	5
ratio of opg	5
corrected for multiple	5
would result in	5
effect of ang	5
injury with mortality	5
reninangiotensin system in	5
the relationship between	5
and nitric oxide	5
elevated blood pressure	5
in the progression	5
accumulation in the	5
important role of	5
it is well	5
to investigate the	5
we suggest that	5
that the ras	5
liver fibrosis in	5
with diabetes with	5
as a homeostatic	5
of mice with	5
the tissue ras	5
in the vascular	5
in conjunction with	5
circulating levels of	5
studies have demonstrated	5
the reduction of	5
in a model	5
which has been	5
glycation end products	5
and those with	5
therapy in patients	5
been proposed to	5
p map kinase	5
generated by the	5
the response to	5
in the rostral	5
primers vk and	5
and high dose	5
role for ace	5
for ace in	5
trabecular bone area	5
of tumor cell	5
the brain renin	5
at receptor gene	5
ang ii has	5
pressure response to	5
of early dn	5
treatment with the	5
and vlp groups	5
expression of tgf	5
of viral particles	5
all of these	5
receptor in angiotensin	5
to activation of	5
insertion deletion polymorphism	5
higher crude mortality	5
the increase of	5
renin activity and	5
on renal angiotensin	5
ii receptor type	5
of the central	5
of bone marrow	5
and development of	5
the function and	5
has been also	5
lead to increased	5
creative commons attribution	5
used as a	5
in the united	5
of glomerular podocytes	5
virus entry and	5
implications for the	5
can lead to	5
plasma membrane by	5
pulmonary blood flow	5
human vascular smooth	5
facilitates viral entry	5
with that of	5
induced diabetic mice	5
associated with aging	5
spike proteins of	5
factors such as	5
disease in the	5
the roles of	5
the composition of	5
diabetic kidney disease	5
the ability to	5
and renal function	5
blood pressure by	5
production and cellular	5
on the surface	5
data suggest that	5
of reactive oxygen	5
well as in	5
angiotensinogen and angiotensin	5
could not be	5
polymorphisms in the	5
for at r	5
diabetic nephropathy by	5
effect on the	5
rats treated with	5
the prevalence of	5
to the effects	5
upregulation of the	5
authors declare no	5
removal of senescent	5
to examine the	5
the sars virus	5
patients admitted to	5
with regards to	5
vitamin d deficiency	5
detected in the	5
effect of losartan	5
function of ras	5
are reported to	5
in the cns	5
endothelial nitric oxide	5
both of these	5
vk and vk	5
molecular mechanisms of	5
development of severe	5
vk were used	5
was found in	5
with and without	5
use of these	5
shown to reduce	5
to cause transformation	5
the epidermal growth	5
the development and	5
chronic heart failure	5
amino acids from	5
there were studies	5
at receptor antagonist	5
lung injury angiotensin	5
important to note	5
enzyme after myocardial	5
to be associated	5
cleaved by ace	5
of these genes	5
exerts its actions	5
research on the	5
role of ras	5
attributed to the	5
the metabolism of	5
been proposed that	5
context of covid	5
demonstrated no significant	5
a new target	5
of the n	5
is caused by	5
mortality in patients	5
of these cells	5
captopril on bone	5
effects of these	5
enzyme activity in	5
axes of the	5
catalytic activity of	5
of renin and	5
at increased risk	5
china clinical characteristics	5
physiological and pathophysiological	5
have a greater	5
manipulation of the	5
direct or indirect	5
system in cardiovascular	5
suggested that ang	5
with acute respiratory	5
these drugs in	5
hepatic stellate cells	5
at receptors mediate	5
ii to form	5
generated from ang	5
those of ang	5
was expressed at	5
the involvement of	5
the ras was	5
hypertension in the	5
significant differences in	5
and response to	5
enzyme and angiotensin	5
as a viral	5
critical illness with	5
in human vascular	5
structural and functional	5
type a receptor	5
to inhibit the	5
small cell lung	5
the bone marrow	5
in human podocytes	5
the inhibition of	5
cohort of patients	5
an endogenous ligand	5
there might be	5
should be noted	5
arb users and	5
ang ii or	5
in the endothelium	5
type ii pneumocytes	5
resulting in the	5
endothelial dysfunction and	5
high concentration of	5
the benefits of	5
as previously described	5
renal ace expression	5
hypertension and cardiovascular	5
been attributed to	5
with low dose	5
a new coronavirus	5
renal function in	5
and lung tumor	5
early stage of	5
circulating or local	5
in the s	5
regulate blood pressure	5
target for the	5
ras plays a	5
yet to be	5
view of ras	5
of lung fibrosis	5
account for the	5
is one of	5
s and s	5
states such as	5
factors associated with	5
of opg rankl	5
plasma acetate levels	5
use of either	5
amino acid from	5
which might be	5
in which cells	5
blood flow in	5
revealed that the	5
local tissue ras	5
and patients with	5
ahead of print	5
of the interaction	5
neutral amino acid	5
an inhibitor of	5
risk for covid	5
protein kinase a	5
as a target	5
downregulation of angiotensin	5
with mortality in	5
there are no	5
of patients who	5
of ras dysregulation	5
by which the	5
studies of the	5
of ras blockers	5
ligand for the	5
abdominal aortic aneurysm	5
spike protein and	5
for the use	5
local ras in	5
the two axes	5
a series of	5
the lung and	5
recombinant human angiotensin	5
can be induced	5
and severe critical	5
was based on	5
a significant reduction	5
recognition of sars	5
be related to	5
functions of the	5
binding of sars	5
the upregulation of	5
ras inhibitors in	5
type i receptor	5
protective effects of	5
pathological cardiac hypertrophy	5
cardiovascular effects of	5
terminal transmembrane domain	5
may account for	5
sars coronavirus spike	5
promoting effects of	5
of the lungs	5
virus infection and	5
functions as a	5
generating ang ii	5
the concept of	5
and transforming growth	5
immune responses to	5
of acute respiratory	5
the identification of	5
to the membrane	5
the balance of	5
ii to ang	5
could also be	5
blocked by a	5
of the heart	5
the spontaneously hypertensive	5
with cardiovascular disease	5
also been shown	5
cellular senescence in	5
ace is an	5
induced vascular senescence	5
in a sex	5
reported to be	5
inhibitors and risk	5
a recent meta	5
arb users with	5
heart and kidneys	5
in the current	5
that the expression	5
the lung is	5
at the n	5
conversion of angiotensin	5
tissue levels of	5
and in a	5
blockade on renal	5
in podocyte injury	5
shown in fig	5
in keeping with	5
the current pandemic	5
and vk were	5
bound to the	5
in cardiovascular diseases	5
balance of the	5
been shown in	5
there was a	5
has been made	5
activated at r	5
molecular and cellular	5
of the host	5
mediated by angiotensin	5
these findings are	5
a large number	5
over the past	4
the prevention and	4
ras in cardiovascular	4
of human angiotensin	4
depends on ace	4
plasma ang ii	4
potential target for	4
under the terms	4
of heart failure	4
of liver fibrosis	4
regions of the	4
within the lung	4
that compared with	4
cov spike protein	4
the pdr locus	4
the protective effect	4
platelet aggregation and	4
complexed with receptor	4
higher in patients	4
end of the	4
angiotensin iii in	4
produce ang ii	4
than that in	4
the measurement of	4
hydrolysis of biological	4
pneumonia outbreak associated	4
there are a	4
coagulation and inflammation	4
the treatment with	4
mechanism of the	4
of angiotensin type	4
may not be	4
protein to the	4
potential influence of	4
renal and cardiac	4
trial of recombinant	4
brain ras is	4
in patients infected	4
the time of	4
has been recommended	4
increased in the	4
to reduced ratio	4
with preserved ejection	4
manifestations of covid	4
reduced ratio of	4
demonstrate that ras	4
angiotensin at receptor	4
of the caax	4
ill patients with	4
ang ii effects	4
in vivo the	4
figure and table	4
blood pressure control	4
die of covid	4
and smooth muscle	4
type receptor blocker	4
homologue of ace	4
be used in	4
and beyond the	4
disintegrin and metalloproteinase	4
angiotensin ii with	4
clinical and experimental	4
and cell growth	4
the virus in	4
association of ace	4
respiratory tract infections	4
characteristics of hospitalized	4
signaling in human	4
as an alternative	4
existence of an	4
and pathogenesis of	4
in wuhan clinical	4
production of ros	4
in vitro ace	4
and renal tissues	4
and the associated	4
link between the	4
viral spike protein	4
of fatty acids	4
glomerular filtration membrane	4
to the severity	4
were observed in	4
renal fanconi syndrome	4
ace is expressed	4
enzyme and its	4
converting enzyme by	4
could lead to	4
glomerular endothelial cells	4
coronavirus of probable	4
and hours were	4
presence of a	4
isolated perfused rat	4
the hallmarks of	4
permeability of the	4
regulator of vascular	4
patients with cardiovascular	4
gene which encodes	4
with more severe	4
patients being analyzed	4
indicated that the	4
be useful to	4
apoptosis in podocytes	4
the unfolded protein	4
and it was	4
gut microbiota might	4
ii in ards	4
with the ras	4
the contribution of	4
a small gtpase	4
membrane protein kc	4
the concentration of	4
to treat resistant	4
as a new	4
in the bile	4
patients with ards	4
are important for	4
it is hoped	4
ace and neprilysin	4
result in the	4
targeting of the	4
to studies that	4
prr in the	4
thrombosis and vasoconstriction	4
and clinical characteristics	4
all of the	4
also responsible for	4
discovery of a	4
could increase the	4
relative to the	4
mediated activation of	4
ace d allele	4
level in normal	4
distress syndrome leads	4
ras inhibitors on	4
removal of the	4
clinical characteristics and	4
the caax motif	4
tumor cell biology	4
furin cleavage site	4
but not in	4
ras is involved	4
domains of sace	4
of ang iv	4
lipid metabolism disorder	4
and release of	4
of podocytes in	4
acids in length	4
increased risk for	4
to vsmc senescence	4
er stress and	4
the effectiveness of	4
proteins of the	4
and ras l	4
single amino acid	4
increased oxidative stress	4
a yeast two	4
the actin cytoskeleton	4
for patients with	4
cells of oral	4
blood pressure response	4
activation has been	4
a study of	4
that the use	4
of b at	4
against lung fibrosis	4
the x chromosome	4
at the pdr	4
in transgenic mice	4
would lead to	4
associated with hypertension	4
the host receptor	4
decrease in the	4
belongs to the	4
ace may be	4
of each sample	4
genetic analysis of	4
this work was	4
is a type	4
is implicated in	4
and dj donoghue	4
clinical relevance of	4
and endothelial cells	4
may be involved	4
in the circulation	4
ang ii signaling	4
also have a	4
that nep may	4
action of ang	4
there are also	4
in vivo studies	4
consistent with the	4
also involved in	4
the finding that	4
cytokines such as	4
by binding to	4
with aging and	4
the rat brain	4
mortality with the	4
patients in the	4
direct renin inhibition	4
determine the presence	4
roles of angiotensin	4
cleavage of ace	4
the medical literature	4
demonstrated a significant	4
ii generation by	4
of blood vessels	4
resulted in the	4
agonist of the	4
a direct effect	4
reduce the risk	4
of cytokines and	4
as an important	4
with the plasma	4
proinflammatory signaling in	4
not been reported	4
lead to an	4
the host cells	4
serum levels of	4
have shown a	4
similar to those	4
in the clinical	4
alveolar epithelial cell	4
such as ace	4
the focus of	4
in an animal	4
of the active	4
a lower crude	4
a type i	4
genes of the	4
clinically proven protease	4
data from the	4
a statistically non	4
of the expression	4
to be highly	4
the tubular lumen	4
required for normal	4
directly or indirectly	4
cell growth and	4
and fibrosis in	4
the viral infection	4
at r stimulation	4
the juxtaglomerular cells	4
increase of ang	4
course of illness	4
located on the	4
acing out angiotensin	4
be implicated in	4
coding sequence of	4
dn and vlp	4
of agt and	4
may be due	4
map k enzymes	4
of endothelial dysfunction	4
inflammatory cytokines and	4
and other organs	4
required for the	4
cov and mers	4
the original sars	4
the late s	4
role of autophagy	4
the nobel prize	4
of expression of	4
knock down of	4
admission into intensive	4
had a serum	4
functional receptor of	4
ace activities and	4
actions of the	4
in the cirrhotic	4
or local ras	4
ang iv and	4
of the inflammatory	4
to the kidney	4
erbb family receptors	4
the discovery that	4
long term sequelae	4
to be able	4
in rat and	4
activation of ace	4
has been the	4
to the c	4
of diabetes mellitus	4
ii as a	4
minimal change disease	4
r in the	4
an at receptor	4
receptor gene expression	4
activation of circulating	4
with a reduction	4
that nep can	4
with severe disease	4
version of this	4
concentration of ang	4
the plasma acetate	4
an analysis based	4
associated with poor	4
that inhibition of	4
of classical ras	4
unger et al	4
to target the	4
gutwein et al	4
accumulation in podocytes	4
existence of a	4
ace i d	4
since its discovery	4
implications of fatal	4
in pancreatic cancer	4
infected with covid	4
a difference in	4
inhibition of ace	4
brain ras in	4
a single amino	4
angiotensin peptide metabolism	4
related to respiratory	4
on liver fibrosis	4
iv and ang	4
the implications for	4
inhibitors and arb	4
ace protein expression	4
the size of	4
of renin inhibitors	4
which is also	4
of the studies	4
sequence of the	4
the studies included	4
was documented to	4
key modulator of	4
a beneficial role	4
the spike proteins	4
users of aceis	4
large body of	4
with or without	4
two active sites	4
and is blocked	4
novel angiotensinconverting enzyme	4
golgi targeting signal	4
the activities of	4
kill tumor cells	4
regard to the	4
apoptosis in the	4
within and beyond	4
pi k pathway	4
is not clear	4
the cell body	4
and loss of	4
transgenic mice with	4
trabecular bone at	4
buss et al	4
chronic administration of	4
bone metabolism in	4
of pulmonary hypertension	4
been described as	4
type receptor gene	4
product of the	4
diabetic kidney injury	4
and is prevented	4
mortality estimates for	4
group with severe	4
studies suggest that	4
a decoy peptide	4
of nadph oxidase	4
control of blood	4
participate in the	4
these data suggest	4
closely related to	4
have been described	4
outbreak associated with	4
was performed using	4
active site cleft	4
evidence indicates that	4
parts of the	4
that tissue ras	4
from the cell	4
protein kc hart	4
course of the	4
of animal models	4
a novel angiotensinconverting	4
the systemic ras	4
system in health	4
activity of ras	4
the process of	4
of the infection	4
experimental heart failure	4
studies were performed	4
are consistent with	4
role of neprilysin	4
study association of	4
as the sars	4
to podocyte injury	4
chronic ras activation	4
between gut microbiota	4
inhibits development of	4
wt and ras	4
of the gene	4
patients with pre	4
sodium delivery to	4
and evolution of	4
both ace inhibitors	4
protein interaction inhibitors	4
in diabetic angiotensin	4
was significantly higher	4
in the kallikrein	4
of the transmembrane	4
activation and aggregation	4
in the present	4
patients with cirrhosis	4
myocardial ace expression	4
in aged mice	4
angii type receptor	4
of renal injury	4
ii at r	4
effects of renin	4
it can be	4
at least in	4
there is also	4
system in human	4
times more likely	4
renin in the	4
immune response to	4
soluble form of	4
in human heart	4
angiotensin receptor type	4
new insights into	4
that has been	4
diagnosis and treatment	4
prevented by angiotensin	4
renal sodium and	4
randomised controlled trials	4
into the circulation	4