This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
quadgram | frequency |
---|---|
severe acute respiratory syndrome | 73 |
angiotensin ii type receptor | 64 |
acute respiratory distress syndrome | 46 |
has been shown to | 38 |
vascular smooth muscle cells | 36 |
acute respiratory syndrome coronavirus | 36 |
in patients with covid | 28 |
of angiotensin converting enzyme | 28 |
with the use of | 27 |
in addition to the | 24 |
of severe acute respiratory | 24 |
components of the ras | 23 |
to the plasma membrane | 23 |
the angiotensin ii type | 23 |
the use of aceis | 23 |
angiotensin ii receptor blockers | 22 |
converting enzyme inhibitors and | 22 |
use of aceis arbs | 22 |
on the other hand | 21 |
an important role in | 21 |
and angiotensin ii receptor | 20 |
the renin angiotensin system | 19 |
have been shown to | 19 |
in the pathogenesis of | 19 |
in the development of | 19 |
enzyme inhibitors and angiotensin | 19 |
use of an acei | 18 |
systematic review and meta | 17 |
in the treatment of | 17 |
of the ras in | 17 |
the central nervous system | 17 |
of an acei arb | 16 |
patients with coronavirus disease | 16 |
vascular endothelial growth factor | 15 |
inhibitors and angiotensin receptor | 15 |
of the renin angiotensin | 15 |
studies that provided adjusted | 15 |
in the regulation of | 14 |
and angiotensin receptor blockers | 14 |
role of the renin | 14 |
angiotensin i to angiotensin | 14 |
for the treatment of | 14 |
epidermal growth factor receptor | 14 |
the use of ras | 14 |
in vascular smooth muscle | 14 |
of the angiotensin ii | 14 |
in spontaneously hypertensive rats | 14 |
use of ras inhibitors | 14 |
of developing severe critical | 14 |
vitro and in vivo | 13 |
in vitro and in | 13 |
in the central nervous | 13 |
effects of ang ii | 13 |
angiotensin ii receptor antagonist | 13 |
in the context of | 13 |
in the absence of | 13 |
of aceis arbs in | 13 |
plays an important role | 13 |
of the ras and | 12 |
in a mouse model | 12 |
ace ang ii at | 12 |
a crucial role of | 12 |
of the brain ras | 12 |
inhibitors and angiotensin ii | 12 |
role of angiotensin converting | 12 |
the dm ab group | 12 |
the risk of mortality | 12 |
in a rat model | 12 |
of ang ii in | 12 |
the use of an | 12 |
of patients infected with | 12 |
studies have shown that | 12 |
has been reported to | 11 |
of patients with covid | 11 |
of the ace gene | 11 |
crucial role of angiotensin | 11 |
r and at r | 11 |
a mouse model of | 11 |
i and ang ii | 11 |
in patients with sars | 11 |
role of ace in | 11 |
between the use of | 11 |
the ras in the | 11 |
it has been reported | 11 |
an angiotensin ii receptor | 10 |
as well as the | 10 |
as a result of | 10 |
to the development of | 10 |
the angiotensin converting enzyme | 10 |
and the risk of | 10 |
middle east respiratory syndrome | 10 |
association between the use | 10 |
a retrospective cohort study | 10 |
the role of the | 10 |
been shown to be | 10 |
ace inhibitors and arbs | 10 |
of angiotensin ii receptor | 10 |
ang i and ang | 10 |
of the mas receptor | 10 |
ii receptor blockers on | 10 |
angiotensin converting enzyme inhibitors | 10 |
at r and at | 10 |
of the ang ii | 10 |
functional receptor for sars | 10 |
in acute respiratory distress | 10 |
a systematic review and | 10 |
in the presence of | 10 |
arm of the ras | 9 |
the severe acute respiratory | 9 |
risk of developing severe | 9 |
converts angiotensin i to | 9 |
in the heart and | 9 |
regulator of the renin | 9 |
the risk of severe | 9 |
expression of at r | 9 |
patients infected with sars | 9 |
the loss of ace | 9 |
at and at receptors | 9 |
an essential regulator of | 9 |
of the ace ang | 9 |
aceis arbs in covid | 9 |
of the at r | 9 |
the activation of the | 9 |
the spike protein of | 9 |
and risk factors for | 9 |
a key role in | 9 |
the role of ace | 9 |
in acute lung injury | 9 |
of the ras pathway | 9 |
regulator of heart function | 9 |
of the at receptor | 9 |
of the classical ras | 9 |
essential regulator of heart | 9 |
functional expression as a | 8 |
respiratory syndrome coronavirus infection | 8 |
of ang ii and | 8 |
mortality of adult inpatients | 8 |
targeted to the plasma | 8 |
ang ii in the | 8 |
activation of at r | 8 |
angiotensin system in the | 8 |
with novel coronavirus in | 8 |
of angiotensin ii type | 8 |
patients with novel coronavirus | 8 |
in individuals with diabetes | 8 |
adult inpatients with covid | 8 |
has been reported that | 8 |
converting enzyme in the | 8 |
normal lung tissue and | 8 |
cloning and functional expression | 8 |
of adult inpatients with | 8 |
and functional expression as | 8 |
in the cardiovascular system | 8 |
a crucial role in | 8 |
time to the virus | 8 |
of vascular smooth muscle | 8 |
outcomes in patients with | 8 |
exposure time to the | 8 |
is an essential regulator | 8 |
in the risk of | 8 |
in the pathophysiology of | 8 |
for mortality of adult | 8 |
of ace in the | 8 |
compared to the non | 8 |
in a variety of | 8 |
in normal lung tissue | 8 |
spike protein of sars | 8 |
risk factors for mortality | 8 |
a human homolog of | 8 |
course and risk factors | 8 |
a rat model of | 8 |
clinical course and risk | 8 |
of severe critical outcomes | 8 |
compared with the control | 8 |
ii type receptor blockade | 8 |
infected with novel coronavirus | 8 |
factors for mortality of | 8 |
it is reasonable to | 8 |
induced by angiotensin ii | 8 |
of angiotensin ii receptors | 8 |
developing severe critical illness | 8 |
a central role in | 8 |
it is important to | 8 |
a l p r | 7 |
the expression of the | 7 |
the protein expression of | 7 |
a negative regulator of | 7 |
has been found that | 7 |
a critical role in | 7 |
ang i to ang | 7 |
receptor blockers on cardiac | 7 |
it has been suggested | 7 |
it has been found | 7 |
of transforming growth factor | 7 |
the effects of ang | 7 |
j o u r | 7 |
in patients with diabetes | 7 |
axis of the ras | 7 |
risk of severe critical | 7 |
nih t cells were | 7 |
l p r e | 7 |
of ang ii to | 7 |
of the ras system | 7 |
with diabetes infected with | 7 |
patients infected with novel | 7 |
activation of the ras | 7 |
in patients with chronic | 7 |
been shown to have | 7 |
in the dm ab | 7 |
converting enzyme is a | 7 |
r n a l | 7 |
blockers on cardiac angiotensin | 7 |
attenuates the progression of | 7 |
p r o o | 7 |
clinical characteristics of coronavirus | 7 |
inhibitors in patients with | 7 |
u r n a | 7 |
in chronic kidney disease | 7 |
r o o f | 7 |
of coronavirus disease in | 7 |
the association between the | 7 |
it is possible that | 7 |
o u r n | 7 |
enzyme is an essential | 7 |
no conflict of interest | 7 |
in the lung tumor | 7 |
enzyme inhibition and angiotensin | 7 |
in hospitalized patients with | 7 |
and oxidative stress in | 7 |
n a l p | 7 |
features of patients infected | 7 |
actions of ang ii | 7 |
by angiotensin ii in | 7 |
the conversion of ang | 7 |
receptor for sars coronavirus | 7 |
converting enzyme protects from | 7 |
reported a higher crude | 7 |
with severe acute respiratory | 7 |
coronavirus disease in china | 7 |
patients with type diabetes | 7 |
regulator of the ras | 7 |
at the same time | 7 |
angiotensin converting enzyme inhibitor | 7 |
of the plasma membrane | 7 |
characteristics of coronavirus disease | 7 |
system inhibitors in patients | 7 |
expression as a captopril | 7 |
angiotensin ii receptor subtypes | 7 |
that provided adjusted estimates | 7 |
that ang ii could | 7 |
has been suggested that | 7 |
plays a role in | 7 |
the formation of ang | 7 |
the lung tumor tissue | 7 |
were found to be | 7 |
with lower odds of | 7 |
renin angiotensin system in | 7 |
in patients with coronavirus | 7 |
of ace inhibitors and | 7 |
patients hospitalized with covid | 7 |
clinical features of patients | 7 |
inhibitors of the renin | 7 |
ace inhibitors and at | 7 |
prevention and treatment of | 7 |
for severe critical outcomes | 7 |
inhibition and angiotensin ii | 7 |
of ang i and | 7 |
of podocyte injury in | 7 |
converting enzyme is an | 6 |
from severe acute lung | 6 |
the effects of the | 6 |
infected patients linked to | 6 |
ectodomain shedding of the | 6 |
the mrna expressions of | 6 |
severe acute lung failure | 6 |
shedding of the severe | 6 |
vascular smooth muscle cell | 6 |
ncov infected patients linked | 6 |
of aceis arbs and | 6 |
viral loads and lung | 6 |
under the control of | 6 |
angiotensin receptor blockers on | 6 |
significant association with lower | 6 |
binding domain complexed with | 6 |
a wide variety of | 6 |
in experimental models of | 6 |
derivatives of ras l | 6 |
in the gastrointestinal tract | 6 |
the risk of covid | 6 |
membrane versions of ras | 6 |
of the ras are | 6 |
integral membrane versions of | 6 |
human bronchial epithelial cells | 6 |
in cardiovascular and renal | 6 |
correction for multiple comparisons | 6 |
plays a crucial role | 6 |
mediates regulated ectodomain shedding | 6 |
in patients with type | 6 |
involvement of the ras | 6 |
a first step in | 6 |
death in patients with | 6 |
treatment with ace inhibitors | 6 |
a high level of | 6 |
converting enzyme inhibition and | 6 |
the rostral ventrolateral medulla | 6 |
illness with the use | 6 |
ace expression in rat | 6 |
the structure of the | 6 |
as an integral membrane | 6 |
angiotensin ii receptor blocker | 6 |
the ace ang ii | 6 |
into intensive care units | 6 |
tissue distribution of ace | 6 |
to the risk of | 6 |
molecular mechanisms and potential | 6 |
developing severe critical disease | 6 |
has been identified as | 6 |
effect of angiotensin ii | 6 |
and angiotensin converting enzyme | 6 |
inhibitors angiotensin receptor blockers | 6 |
mechanisms and potential therapeutic | 6 |
a functional receptor for | 6 |
may be associated with | 6 |
by blockade of angiotensin | 6 |
components of the renin | 6 |
play an important role | 6 |
angiotensin ii production and | 6 |
human homolog of angiotensin | 6 |
in subjects with diabetes | 6 |
connective tissue growth factor | 6 |
the angiotensin type receptor | 6 |
and vascular smooth muscle | 6 |
as a consequence of | 6 |
first step in understanding | 6 |
ace inhibitors or arbs | 6 |
converting enzyme in human | 6 |
hospitalized patients with covid | 6 |
system blockers and the | 6 |
and potential therapeutic target | 6 |
step in understanding sars | 6 |
sodium and water absorption | 6 |
loads and lung injury | 6 |
be involved in the | 6 |
difference in the risk | 6 |
the components of the | 6 |
podocytes cultured in vitro | 6 |
in patients with advanced | 6 |
in the ace gene | 6 |
in understanding sars pathogenesis | 6 |
in lung tumor tissue | 6 |
ang ii and ang | 6 |
and biochemical indexes from | 6 |
to severe acute respiratory | 6 |
conversion of ang i | 6 |
an integral membrane protein | 6 |
in the dm group | 6 |
the glomerular basement membrane | 6 |
provided adjusted mortality estimates | 6 |
ii type receptor in | 6 |
is involved in the | 6 |
outcomes of patients with | 6 |
patients linked to viral | 6 |
linked to viral loads | 6 |
aldosterone system inhibitors in | 6 |
protects from severe acute | 6 |
enzyme inhibitors angiotensin receptor | 6 |
east respiratory syndrome coronavirus | 6 |
induced acute lung injury | 6 |
converting enzyme inhibitors angiotensin | 6 |
receptor for the sars | 6 |
for the prevention of | 6 |
is highly expressed in | 6 |
play a role in | 6 |
enzyme protects from severe | 6 |
in addition to its | 6 |
it was found that | 6 |
effects of ras inhibitors | 6 |
of the components of | 6 |
of ang ii by | 6 |
the functional receptor for | 6 |
expression of ace in | 6 |
the protective arm of | 6 |
the mrna expression of | 6 |
clinical and biochemical indexes | 6 |
ace inhibitors and angiotensin | 6 |
to viral loads and | 6 |
the effects of ace | 6 |
distribution of ace protein | 6 |
protective arm of ras | 6 |
in the brain and | 6 |
no conflicts of interest | 6 |
and its role in | 6 |
ii in the brain | 6 |
regulated ectodomain shedding of | 6 |
advanced glycation end products | 5 |
hypertension and diabetes mellitus | 5 |
have been identified in | 5 |
the discovery of ace | 5 |
to an increase in | 5 |
that reported a higher | 5 |
such as hypertension and | 5 |
mediated by at receptors | 5 |
of vascular endothelial growth | 5 |
in patients with hypertension | 5 |
and the development of | 5 |
receptor in angiotensin ii | 5 |
compared to those with | 5 |
use of these drugs | 5 |
with the control group | 5 |
plays a key role | 5 |
manipulation of the ras | 5 |
on the role of | 5 |
of the ras has | 5 |
at receptors in the | 5 |
i to ang ii | 5 |
in angiotensin ii production | 5 |
structural basis for the | 5 |
a large number of | 5 |
ras in the lung | 5 |
was shown to be | 5 |
lung tissue and lung | 5 |
and cellular responses to | 5 |
ligand for the g | 5 |
in vascular endothelial cells | 5 |
the at r and | 5 |
association of cardiac injury | 5 |
of at r in | 5 |
of hxt and hxt | 5 |
more likely to die | 5 |
central role in the | 5 |
the regulation of the | 5 |
and risk of cancer | 5 |
cardiac injury with mortality | 5 |
has also been shown | 5 |
nonproteolytic activation of prorenin | 5 |
an essential role in | 5 |
the sympathetic nervous system | 5 |
acei arb users and | 5 |
endothelial nitric oxide synthase | 5 |
for the sars coronavirus | 5 |
in the united states | 5 |
production and cellular responses | 5 |
tissue and lung tumor | 5 |
acei arb users with | 5 |
corrected for multiple comparisons | 5 |
that provided adjusted mortality | 5 |
among patients with covid | 5 |
acting on the ras | 5 |
converting enzyme and angiotensin | 5 |
rate for severe critical | 5 |
to the activation of | 5 |
inhibitors and risk of | 5 |
an acei arb was | 5 |
in the rostral ventrolateral | 5 |
structure and function of | 5 |
with type diabetes and | 5 |
the heart and kidneys | 5 |
role in maintaining the | 5 |
the authors declare no | 5 |
on the surface of | 5 |
ii production and cellular | 5 |
small cell lung cancer | 5 |
an animal model of | 5 |
innate and adaptive immune | 5 |
in the three groups | 5 |
novel coronavirus in wuhan | 5 |
basis for the recognition | 5 |
with mortality in hospitalized | 5 |
mortality in hospitalized patients | 5 |
should not be used | 5 |
the plasma membrane by | 5 |
in the case of | 5 |
of components of the | 5 |
the progression of diabetic | 5 |
human vascular smooth muscle | 5 |
patients with hypertension hospitalized | 5 |
use of arbs and | 5 |
of acute respiratory distress | 5 |
of reactive oxygen species | 5 |
it is clear that | 5 |
cellular responses to renin | 5 |
is an endogenous ligand | 5 |
demonstrated no significant difference | 5 |
formation of ang ii | 5 |
vk and vk were | 5 |
vascular senescence and sasp | 5 |
of the protective arm | 5 |
reactive oxygen species in | 5 |
and vk were used | 5 |
of captopril on bone | 5 |
effect of captopril on | 5 |
effects of the ace | 5 |
ii type receptor and | 5 |
vk were used to | 5 |
for the recognition of | 5 |
the use of arbs | 5 |
of the ace angiotensin | 5 |
effects on blood pressure | 5 |
in health and disease | 5 |
targeted derivatives of ras | 5 |
angiotensin converting enzyme in | 5 |
myocardial infarction by blockade | 5 |
to the effects of | 5 |
enzyme after myocardial infarction | 5 |
in the general population | 5 |
of the reninangiotensin system | 5 |
of epidermal growth factor | 5 |
of severe critical illness | 5 |
high dose of captopril | 5 |
our understanding of the | 5 |
may play a role | 5 |
the production of ang | 5 |
has been proposed that | 5 |
the development and progression | 5 |
has not yet been | 5 |
of cardiac injury with | 5 |
of angiotensin ii and | 5 |
development of glomerulosclerosis in | 5 |
of novel coronavirus pneumonia | 5 |
system blockade on renal | 5 |
it is likely that | 5 |
arb users and non | 5 |
ras to the plasma | 5 |
of patients with coronavirus | 5 |
there is no evidence | 5 |
compared with that of | 5 |
endogenous ligand for the | 5 |
is one of the | 5 |
after myocardial infarction by | 5 |
therapy in patients with | 5 |
a lower risk of | 5 |
levels of ang ii | 5 |
association with lower odds | 5 |
to the regulation of | 5 |
sodium and water retention | 5 |
role for ace in | 5 |
prorenin receptor in angiotensin | 5 |
as well as in | 5 |
renin angiotensin system and | 5 |
stimulation of at r | 5 |
a role in the | 5 |
c domain of sace | 5 |
aldosterone system inhibitors and | 5 |
was found to be | 5 |
disease and ulcerative colitis | 5 |
crude rate for severe | 5 |
important role in the | 5 |
functional receptor for the | 5 |
the epidermal growth factor | 5 |
in the progression of | 5 |
blockade on renal angiotensin | 5 |
of ang i to | 5 |
crystal structure of the | 5 |
the beneficial effects of | 5 |
disease severity in covid | 5 |
angiotensin ii at receptor | 5 |
forming enzymes and receptors | 5 |
ratio of opg rankl | 5 |
angiotensin receptor blockers and | 5 |
development and progression of | 5 |
converting enzyme after myocardial | 5 |
converting enzyme activity in | 5 |
cardiovascular disease and hypertension | 5 |
should be noted that | 5 |
lower risk of mortality | 5 |
the c domain of | 5 |
transforming growth factor beta | 5 |
of the novel coronavirus | 5 |
oxidative stress in the | 5 |
blockade of angiotensin ii | 5 |
in an attempt to | 5 |
and the expression of | 5 |
injury with mortality in | 5 |
an endogenous ligand for | 5 |
in the early stage | 5 |
one of the most | 5 |
china clinical characteristics of | 5 |
severe critical illness with | 5 |
release of inflammatory cytokines | 5 |
to be associated with | 5 |
between acei arb users | 5 |
effects of ace inhibitors | 5 |
with acute respiratory distress | 5 |
pivotal role of the | 5 |
of ace expressing cells | 5 |
hospitalized patients with novel | 5 |
loss of ace in | 5 |
ras in the gastrointestinal | 5 |
angiotensin ii type a | 5 |
of the ace axis | 5 |
characteristics and outcomes of | 5 |
it has been proposed | 5 |
critical illness with the | 5 |
the development of the | 5 |
removal of senescent cells | 5 |
those of ang ii | 5 |
in which cells were | 5 |
it should be noted | 5 |
be due to the | 5 |
by angiotensin ii type | 5 |
in patients with severe | 5 |
effects of angiotensin ii | 5 |
for the g protein | 5 |
infarction by blockade of | 5 |
in the brain of | 5 |
negative regulator of the | 5 |
the recognition of sars | 5 |
and transforming growth factor | 5 |
significantly associated with lower | 5 |
ang ii and at | 5 |
blockade of the renin | 5 |
the expression of ras | 5 |
tmprss and is blocked | 4 |
in the collecting duct | 4 |
to the mas receptor | 4 |
been shown to inhibit | 4 |
inhibitors and at receptor | 4 |
and outcomes of patients | 4 |
angiotensin system in cardiovascular | 4 |
were used to amplify | 4 |
ii type receptor blocker | 4 |
on the potential influence | 4 |
ang ii is a | 4 |
of fatal outcomes of | 4 |
may be due to | 4 |
with regards to the | 4 |
to be involved in | 4 |
increased the expression of | 4 |
activated protein kinase kinase | 4 |
the context of covid | 4 |
novel coronavirus from wuhan | 4 |
ang iv and ang | 4 |
production of ang ii | 4 |
between normal lung tissue | 4 |
a pneumonia outbreak associated | 4 |
its homologue ace and | 4 |
and endothelial dysfunction in | 4 |
that the use of | 4 |
angiotensin converting enzyme gene | 4 |
with preserved ejection fraction | 4 |
inhibits development of glomerulosclerosis | 4 |
be used as a | 4 |
is important to note | 4 |
of ace and ace | 4 |
with that of the | 4 |
blockers on onset and | 4 |
out angiotensin ii in | 4 |
and activation of the | 4 |
of ang ii is | 4 |
the glomerular filtration barrier | 4 |
associated with lower odds | 4 |
biological peptides by human | 4 |
enzyme is a functional | 4 |
angiotensin ii in the | 4 |
renal sodium and water | 4 |
bone of orx mice | 4 |
ii type receptor antagonist | 4 |
view of the ras | 4 |
the heart and kidney | 4 |
blockade inhibits development of | 4 |
cells in the brain | 4 |
to the cardiovascular system | 4 |
syndrome leads to reduced | 4 |
that compared with the | 4 |
is blocked by a | 4 |
the functional receptor of | 4 |
likely to die of | 4 |
inner surface of the | 4 |
the ratio of opg | 4 |
no significant difference with | 4 |
the dm group was | 4 |
increase the production of | 4 |
in a model of | 4 |
careful targeting of the | 4 |
can be induced by | 4 |
coronavirus of probable bat | 4 |
viewpoint on the potential | 4 |
the existence of an | 4 |
the expression of tgf | 4 |
of the active site | 4 |
in the prefusion conformation | 4 |
reduce the risk of | 4 |
effect of ang ii | 4 |
characteristics of hospitalized patients | 4 |
clinical outcomes in covid | 4 |
the ace and ace | 4 |
of ras inhibitors on | 4 |
loss of the protective | 4 |
in patients hospitalized with | 4 |
ace has been identified | 4 |
may be involved in | 4 |
was involved in the | 4 |
ii in ards therapy | 4 |
the ras has been | 4 |
and blood pressure regulation | 4 |
mortality with the use | 4 |
mortality estimates for exclusively | 4 |
trial of recombinant human | 4 |
clinical characteristics of hospitalized | 4 |
of recombinant human ace | 4 |
to studies that provided | 4 |
and is blocked by | 4 |
modulator of the renin | 4 |
ang ii at r | 4 |
a high concentration of | 4 |
by the action of | 4 |
that the expression of | 4 |
sars coronavirus spike receptor | 4 |
kc hart and dj | 4 |
of cases of novel | 4 |
functional receptor of sars | 4 |
gut microbiota in the | 4 |
and at receptor blockers | 4 |
the presence of a | 4 |
angiotensin ii in ards | 4 |
structure of the sars | 4 |
a disintegrin and metalloproteinase | 4 |
role of angiotensin ii | 4 |
the protective role of | 4 |
outbreak associated with a | 4 |
disease in the elderly | 4 |
on the cell membrane | 4 |
reduced ratio of ace | 4 |
associated with aging and | 4 |
neprilysin in angiotensin peptide | 4 |
a single amino acid | 4 |
angiotensin ii in vascular | 4 |
on ace and tmprss | 4 |
effects of at r | 4 |
induced by ang ii | 4 |
ras have been identified | 4 |
in a range of | 4 |
a protective role of | 4 |
of ras in the | 4 |
of neutral amino acids | 4 |
in diabetic kidney disease | 4 |
diabetes infected with sars | 4 |
integral membrane protein kc | 4 |
after correction for multiple | 4 |
is a functional receptor | 4 |
to be able to | 4 |
decrease in blood pressure | 4 |
patients with acute respiratory | 4 |
novel coronavirus pneumonia in | 4 |
of ras in cardiovascular | 4 |
respiratory distress syndrome leads | 4 |
development of neurogenic hypertension | 4 |
infected pneumonia in wuhan | 4 |
limited to studies that | 4 |
and at r in | 4 |
conversion of angiotensin i | 4 |
of gut microbiota in | 4 |
a few small studies | 4 |
new coronavirus of probable | 4 |
has been made in | 4 |
effects of captopril on | 4 |
to reduced ratio of | 4 |
and is prevented by | 4 |
the course of the | 4 |
more likely to have | 4 |
increases ace expression in | 4 |
in response to high | 4 |
of critically ill patients | 4 |
homologue ace and neprilysin | 4 |
the epithelial cells of | 4 |
it was demonstrated that | 4 |
primers vk and vk | 4 |
within and beyond the | 4 |
the existence of the | 4 |
or angiotensin receptor blockers | 4 |
is a key modulator | 4 |
the ace ace balance | 4 |
critical illness from covid | 4 |
it has been shown | 4 |
ace deficiency accentuates vascular | 4 |
clinical characteristics of patients | 4 |
in patients infected with | 4 |
loss of ace expressing | 4 |
with ace inhibitors or | 4 |
associated with the use | 4 |
of the dm group | 4 |
and facilitates viral entry | 4 |
the progression of dn | 4 |
axis of the renin | 4 |
of aceis and arbs | 4 |
of the interaction between | 4 |
aortic smooth muscle cells | 4 |
of the renin prorenin | 4 |
onset and severity of | 4 |
effect of ace inhibitors | 4 |
ace and tmprss and | 4 |
a key modulator of | 4 |
no increased risk of | 4 |
increase the risk of | 4 |
to treat resistant hypertension | 4 |
of blood pressure in | 4 |
the renin prorenin receptor | 4 |
the at r is | 4 |
the spike proteins of | 4 |
an analysis based on | 4 |
sodium delivery to the | 4 |
of death in patients | 4 |
the pathogenesis of podocyte | 4 |
leads to reduced ratio | 4 |
amino acids in length | 4 |
ii type receptor gene | 4 |
for exclusively hypertensive patients | 4 |
senescence in vascular smooth | 4 |
the treatment of hypertension | 4 |
use of angiotensin converting | 4 |
surface of the plasma | 4 |
progression of diabetic nephropathy | 4 |
higher in patients with | 4 |
in the spontaneously hypertensive | 4 |
with a new coronavirus | 4 |
of ace and the | 4 |
cases of novel coronavirus | 4 |
and lung tumor tissue | 4 |
angiotensin system and the | 4 |
of the spike protein | 4 |
fission and er stress | 4 |
implications of fatal outcomes | 4 |
times more likely to | 4 |
an increase in the | 4 |
in the expression of | 4 |
in blood pressure regulation | 4 |
existence of the brain | 4 |
patients with diabetes mellitus | 4 |
converting enzyme and its | 4 |
in accordance with the | 4 |
version of this article | 4 |
in diabetic angiotensin ii | 4 |
the potential influence of | 4 |
and the implications for | 4 |
a significant decrease in | 4 |
fibrosis and pulmonary hypertension | 4 |
mortality in patients with | 4 |
proteolytic cleavage of ace | 4 |
the generation of ang | 4 |
the crystal structure of | 4 |
system in health and | 4 |
severe acute respiratory distress | 4 |
ang ii has been | 4 |
with the plasma membrane | 4 |
declare no conflict of | 4 |
been identified as a | 4 |
at increased risk for | 4 |
this work was supported | 4 |
mas axis of the | 4 |
in db db mice | 4 |
as the receptor for | 4 |
neutral amino acid transporter | 4 |
at r and masr | 4 |
angiotensin system in human | 4 |
receptor blockade inhibits development | 4 |
acing out angiotensin ii | 4 |
the angiotensin ii receptor | 4 |
might be involved in | 4 |
definitions of severe critical | 4 |
a reduction in the | 4 |
severe critical disease compared | 4 |
structure of sars coronavirus | 4 |
is prevented by angiotensin | 4 |
both ace inhibitors and | 4 |
of sars coronavirus spike | 4 |
ras wt and ras | 4 |
an increase in ace | 4 |
of probable bat origin | 4 |
in patients with cirrhosis | 4 |
been identified in the | 4 |
important to note that | 4 |
potential influence of angiotensin | 4 |
a higher crude mortality | 4 |
regards to the risk | 4 |
is a key mechanism | 4 |
tumor necrosis factor alpha | 4 |
experimental and clinical studies | 4 |
level in normal lung | 4 |
the nucleus tractus solitarius | 4 |
single amino acid from | 4 |
the ras system in | 4 |
with regard to the | 4 |
of mortality with the | 4 |
pi k akt pathway | 4 |
control of blood pressure | 4 |
efficacy and safety of | 4 |
in view of the | 4 |
conversion of ang ii | 4 |
relative to the non | 4 |
the development of neurogenic | 4 |
of expression of the | 4 |
of recombinant human angiotensin | 4 |
smooth muscle cells and | 4 |
higher crude mortality rate | 4 |
of the ace receptor | 4 |
of gut microbiota and | 4 |
cardiovascular implications of fatal | 4 |
in the early s | 4 |
ace activity in the | 4 |
effects of these drugs | 4 |
ace deficiency leads to | 4 |
on the epithelial cells | 4 |
estimates for severe critical | 4 |
was identified as a | 4 |
epithelial cells of oral | 4 |
development of severe critical | 4 |
play a central role | 4 |
blood pressure response to | 4 |
angiotensin system in health | 4 |
promote the production of | 4 |
of patients admitted to | 4 |
the effect of aceis | 4 |
it is not surprising | 4 |
angiotensin i converting enzyme | 4 |
dn and vlp groups | 4 |
in the lungs of | 4 |
a higher crude rate | 4 |
protein kc hart and | 4 |
the inner surface of | 4 |
hydrolysis of biological peptides | 4 |
of ang ii into | 4 |
genes were found to | 4 |
admission into intensive care | 4 |
at r in the | 4 |
higher crude rate for | 4 |
entry into host cells | 4 |
key modulator of the | 4 |
ang ii type receptor | 4 |
ace activities and is | 4 |
response to ang ii | 4 |
of the creative commons | 4 |
and tmprss and is | 4 |
the use of renin | 4 |
and adaptive immune responses | 4 |
of these drugs in | 4 |
ii type a receptor | 4 |
and in a sex | 4 |
and severe critical outcomes | 4 |
in support of this | 4 |
mitochondrial fission and er | 4 |
importance of ras in | 4 |
difference with regards to | 4 |
of biological peptides by | 4 |
a new target for | 4 |
as a therapeutic target | 4 |
with hypertension and diabetes | 4 |
lung fibrosis and pulmonary | 4 |
it is hoped that | 4 |
morbidity and mortality in | 4 |
the activity of the | 4 |
been shown to reduce | 4 |
of the virus and | 4 |
the exposure time to | 4 |
role of autophagy in | 4 |
diabetic angiotensin ii type | 4 |
disease in china clinical | 4 |
as a receptor for | 4 |
and severity of severe | 4 |
effects of the angiotensin | 4 |
involved in the pathogenesis | 4 |
and sudden cardiac death | 4 |
might lead to increased | 4 |
estimates for exclusively hypertensive | 4 |
the glomerular filtration membrane | 4 |
in an animal model | 4 |
ace activity may be | 4 |
of the glomerular basement | 4 |
severe critical illness from | 4 |
of ace expression in | 4 |
the creative commons attribution | 4 |
ii type receptor stimulation | 4 |
to the severity of | 4 |
glomerulosclerosis in diabetic angiotensin | 4 |
both of which are | 4 |
was based on the | 4 |
the integrity of the | 4 |
crucial role in the | 4 |
of the ras with | 4 |
domain complexed with receptor | 4 |
distress syndrome leads to | 4 |
ang ii into ang | 4 |
protective arms of ras | 4 |
expression of the ace | 4 |
expression of the genes | 4 |
activities and is prevented | 4 |
that ace is the | 4 |
or an angiotensin ii | 4 |
blockers and the risk | 4 |
been shown to induce | 4 |
in the generation of | 4 |
ang ii to form | 4 |
ang ii to ang | 4 |
angiotensin converting enzyme activity | 4 |
to be one of | 4 |
the at r in | 4 |
ace inhibitors and arb | 4 |
expression profiling of ace | 4 |
the ras and the | 4 |
prorenin receptor blockade inhibits | 4 |
determine the presence of | 4 |
risk of mortality with | 4 |
global loss of ace | 4 |
the pi k akt | 4 |
the coding sequence of | 4 |
on onset and severity | 4 |
odds of developing severe | 4 |
polymorphisms in the ace | 4 |
feedback activation of circulating | 4 |
to die of covid | 4 |
receptor blockers on onset | 4 |
of glomerulosclerosis in diabetic | 4 |
on the risk of | 4 |
fatal outcomes of patients | 4 |
severity of severe acute | 4 |
angiotensin ii and angiotensin | 4 |
distributed under the terms | 4 |
ace and neprilysin in | 4 |
a clinically proven protease | 4 |
pneumonia outbreak associated with | 4 |
a new coronavirus of | 4 |
by a clinically proven | 4 |
of ace ace activities | 4 |
ace ace activities and | 4 |
critically ill patients with | 4 |
for the use of | 4 |
a novel target for | 4 |
regulation of captopril on | 4 |
of the intrarenal renin | 4 |
may serve as a | 4 |
gut microbiota might be | 4 |
the unfolded protein response | 4 |
the prevention and treatment | 4 |
cell entry depends on | 4 |
ii receptor blockers with | 4 |
was expressed at a | 4 |
individuals with diabetes with | 4 |
the ability of the | 4 |
a more severe course | 4 |
membrane protein kc hart | 4 |
to the presence of | 4 |
angiotensin ii receptors and | 4 |
epidemiological and clinical characteristics | 4 |
structural studies of sars | 4 |
wt and ras l | 4 |
role in the pathogenesis | 4 |
a novel angiotensinconverting enzyme | 4 |
blood pressure in the | 4 |
also been shown to | 4 |
the receptor for sars | 4 |
the group with severe | 4 |
differences in immune responses | 4 |
in response to ang | 4 |
concentration of ang ii | 4 |
adjusted mortality estimates for | 4 |
in the group with | 4 |
anchored as an integral | 4 |
was associated with increased | 4 |
the balance between the | 4 |
the early stage of | 4 |
renin prorenin receptor in | 4 |
in a number of | 4 |
expression of ace receptor | 4 |
the protective effect of | 4 |
of blood pressure and | 4 |
similar to those of | 4 |
hart and dj donoghue | 4 |
in the formation of | 4 |
associated with a new | 4 |
em structure of the | 4 |
depends on ace and | 4 |
level of expression of | 4 |
ratio of ace ace | 4 |
the use of these | 4 |
and coronary artery disease | 4 |
entry depends on ace | 4 |
cells of oral mucosa | 4 |
the angiotensin ii at | 4 |
the world health organization | 4 |
ras anchored as an | 4 |
of circulating or local | 4 |
is mediated by angiotensin | 4 |
to determine the presence | 4 |
is associated with the | 4 |
blocked by a clinically | 4 |
in angiotensin peptide metabolism | 4 |
and neprilysin in angiotensin | 4 |
induced lung injury angiotensin | 4 |
clinically proven protease inhibitor | 4 |
and the pathogenesis of | 4 |
of hospitalized patients with | 4 |
is critical for the | 4 |
during the course of | 4 |
a viewpoint on the | 4 |
blood pressure and renal | 4 |
a direct or indirect | 4 |
the existence of a | 4 |
mortality among patients with | 4 |
high concentration of glucose | 3 |
distress syndrome during mechanical | 3 |
the risk of developing | 3 |
for blood pressure regulation | 3 |
a protective role in | 3 |
the regulation of glucose | 3 |
incomplete renal fanconi syndrome | 3 |
of the use of | 3 |
cardiac hypertrophy and remodeling | 3 |
by ace to produce | 3 |
syndrome coronavirus and human | 3 |
modulation of captopril on | 3 |
of acute kidney injury | 3 |
ace reduces the progression | 3 |
unable to cause transformation | 3 |
of a local renin | 3 |
moderate level in normal | 3 |
celebrating the th anniversary | 3 |
of the effects of | 3 |
there are a number | 3 |
of angiotensin i and | 3 |
differential downregulation of ace | 3 |
of vasopressin from the | 3 |
long term sequelae of | 3 |
human renin and human | 3 |
in cultured neonatal rat | 3 |
r i p t | 3 |
forming enzyme in brain | 3 |
converting enzyme insertion deletion | 3 |
factor in the development | 3 |
cardiovascular and renal diseases | 3 |
of at r by | 3 |
molecular and cellular mechanisms | 3 |
to be responsible for | 3 |
and human coronavirus nl | 3 |
of the effect of | 3 |
of the transcription factor | 3 |
and atherosclerosis in the | 3 |
with hypertension hospitalized for | 3 |
diabetic nephropathy by a | 3 |
lower odds of developing | 3 |
the role of ras | 3 |
what is the evidence | 3 |
and ulcerative colitis serum | 3 |
the ace gene maps | 3 |
of captopril on skeletal | 3 |
and outcomes among patients | 3 |
ace and ace in | 3 |
found that ang ii | 3 |
strains sky and sky | 3 |
of the insulin receptor | 3 |
viral entry to cells | 3 |
patients who died of | 3 |
at a r and | 3 |
and aceis and arbs | 3 |
aldosterone system blockers and | 3 |
into sky and sky | 3 |
of angiotensin i to | 3 |
to a typical acute | 3 |
downregulation of ace by | 3 |
compared with the dm | 3 |
ang ii generation by | 3 |
to the generation of | 3 |
more severe course of | 3 |
have been demonstrated to | 3 |
of renal injury in | 3 |
arbs compared to the | 3 |
angiotensin ii receptor type | 3 |
likely play upstream roles | 3 |
were included in the | 3 |
chronic obstructive pulmonary disease | 3 |
patients with hypokalaemia compared | 3 |
in response to diet | 3 |
the brain reninangiotensin system | 3 |
contributes to the development | 3 |
and therapeutic intervention protocols | 3 |
critical disease compared to | 3 |
at a moderate level | 3 |
leading to the generation | 3 |
is a member of | 3 |
by ace inhibitors and | 3 |
in patients with hypokalaemia | 3 |
spontaneously hypertensive rats angiotensin | 3 |
with respect to the | 3 |
hypertensive patients with covid | 3 |
a n u s | 3 |
for treatment of covid | 3 |
obvious feedback activation of | 3 |
included hypertensive patients exclusively | 3 |
and severe acute respiratory | 3 |
derivatives of ras wt | 3 |
via the at r | 3 |
to further investigate the | 3 |
atherosclerosis in the apoe | 3 |
stimulation of the angiotensin | 3 |
on the at receptor | 3 |
effects of the ras | 3 |
renin in the brain | 3 |
analyses that were limited | 3 |
arb users with covid | 3 |
mice infused with angii | 3 |
be withdrawn in patients | 3 |
amino acids from the | 3 |
of diabetes and ace | 3 |
required for activation of | 3 |
blockade of the ras | 3 |
on the one hand | 3 |
respiratory syndrome coronavirus spike | 3 |
in the brain is | 3 |
required for those with | 3 |
and the sympathetic nervous | 3 |
the expression of ace | 3 |
respiratory distress syndrome during | 3 |
in hypertensive patients with | 3 |
in human heart failure | 3 |
angiotensin converting enzyme inhibition | 3 |
inhibition of diabetic nephropathy | 3 |
on the epithelial side | 3 |
of cardiac myocytes through | 3 |
the gene which encodes | 3 |
of each sample was | 3 |
plasma renin activity and | 3 |
nephropathy by a decoy | 3 |
ii receptor blockers and | 3 |
s c r i | 3 |
by a decoy peptide | 3 |
and upstream of the | 3 |
ace in complex with | 3 |
a moderate level in | 3 |
in blood pressure control | 3 |
cell proliferation and recruitment | 3 |
myocardial infarction increases ace | 3 |
to the b receptor | 3 |
dm group compared with | 3 |
and vessel exposure to | 3 |
of ventricular fibrillation has | 3 |
myocytes through activation of | 3 |
disease compared to the | 3 |
inhibitors or angiotensin receptor | 3 |
highly correlated with the | 3 |
infected with h n | 3 |
of senescent cells by | 3 |
and function of the | 3 |
level and its expression | 3 |
would like to thank | 3 |
of severe critical disease | 3 |
at r promotes the | 3 |
receptor and regulator of | 3 |
cardiothoracic robotic assisted surgery | 3 |
lead to a typical | 3 |
enhanced and protracted tissue | 3 |
via at r and | 3 |
and reproduction in any | 3 |
analysis based on decade | 3 |
have been reported in | 3 |
it is hypothesized that | 3 |
the beneficial effect of | 3 |
the effect of ras | 3 |
and regulator of the | 3 |
which is available to | 3 |
the expression ratio of | 3 |
in the subfornical organ | 3 |
of ace receptor of | 3 |
the levels of renin | 3 |
expression and activity in | 3 |
deficiency accentuates vascular inflammation | 3 |
those with myocardial dysfunction | 3 |
of the local ras | 3 |
dysbiosis of gut microbiota | 3 |
increased morbidity and mortality | 3 |
the at receptor and | 3 |
i to angiotensin ii | 3 |
map k and map | 3 |
elderly and those with | 3 |
with respect to early | 3 |
the protective arms of | 3 |
for a variety of | 3 |
has been demonstrated in | 3 |
characteristics of cases of | 3 |
inflammatory cytokines such as | 3 |
in myocardial infarcted rat | 3 |
lamina propria mesenchymal cells | 3 |
in the first place | 3 |
ace is widely expressed | 3 |
clearance of senescent cells | 3 |
cov and ace induces | 3 |
weight of the meta | 3 |
the at receptor is | 3 |
risk factor for cvd | 3 |
in the kidney angiotensin | 3 |
ii at receptor axis | 3 |
in the elderly and | 3 |
that the abundance of | 3 |
is increasing evidence that | 3 |
only a few studies | 3 |
the role of autophagy | 3 |
linked mental retardation and | 3 |
implicated in the regulation | 3 |
at the end of | 3 |
the treatment of covid | 3 |
of human bronchial epithelial | 3 |
enzyme in heart failure | 3 |
the presence of heterogeneity | 3 |
of ras components in | 3 |
for severe acute respiratory | 3 |
ii and ang iii | 3 |
of ace by the | 3 |
studies have demonstrated that | 3 |
has been demonstrated by | 3 |
ace inhibitor and arb | 3 |
expression in rat and | 3 |
or risk of death | 3 |
lipid accumulation in podocytes | 3 |
effect of ras inhibitors | 3 |
might be closely related | 3 |
group with severe covid | 3 |
ras in the pathophysiology | 3 |
has been linked to | 3 |
the chinese national health | 3 |
the cyc tt region | 3 |
represents a potential target | 3 |
patients with cirrhosis and | 3 |
ulcerative colitis serum angiotensin | 3 |
spike glycoprotein of sars | 3 |
coronavirus and human coronavirus | 3 |
examining the effects of | 3 |
as a novel therapeutic | 3 |
to a reduction in | 3 |
long structural studies of | 3 |
n u s c | 3 |
mas receptor axis in | 3 |
be attributed to the | 3 |
among patients hospitalized with | 3 |
anniversary of the discovery | 3 |
enzyme by the spike | 3 |
in rat and humans | 3 |
can be attenuated by | 3 |
by angiotensin converting enzyme | 3 |
characteristics of patients infected | 3 |
the development of glomerulosclerosis | 3 |
through the mas receptor | 3 |
recombinant human angiotensinconverting enzyme | 3 |
particularly with respect to | 3 |
a direct effect on | 3 |
targeting of the ras | 3 |
the structure and function | 3 |
of the two x | 3 |
the severity of covid | 3 |
information is available regarding | 3 |
prevention of angiotensin ii | 3 |
of hypertension in spontaneously | 3 |
were limited to studies | 3 |
ace to form a | 3 |
patients with severe disease | 3 |
been identified as the | 3 |
ii has been shown | 3 |
to the formation of | 3 |
hypertension in spontaneously hypertensive | 3 |
a systematic review of | 3 |
the spike protein and | 3 |
the interaction of the | 3 |
have shown that the | 3 |
axes of the ras | 3 |
angiotensin ii and the | 3 |
in experimental heart failure | 3 |
that included hypertensive patients | 3 |
benefits of ace inhibitors | 3 |
severe critical outcomes in | 3 |
the spontaneously hypertensive rat | 3 |
mechanism of lung injury | 3 |
online version of this | 3 |
respiratory syndrome coronavirus and | 3 |
induced vsmc senescence via | 3 |
cardiovascular and renal physiology | 3 |
enzyme in diabetic nephropathy | 3 |
immune responses to viral | 3 |
the discovery of renin | 3 |
aceis arbs and severe | 3 |
ang ii can be | 3 |
the yeast pdr gene | 3 |
loss of ace due | 3 |
transformed into sky and | 3 |
not differ between normal | 3 |
the elderly and those | 3 |
with the ace inhibitor | 3 |
in order to function | 3 |
two axes of the | 3 |
vasodilatation and revision of | 3 |
an increased risk of | 3 |
ace activation promotes antithrombotic | 3 |
and death in patients | 3 |
targeting ras to the | 3 |
spike in the prefusion | 3 |
activation of the mas | 3 |
identified throughout the gastrointestinal | 3 |
mellitus at increased risk | 3 |
induced by testosterone deficiency | 3 |
a direct renin inhibitor | 3 |
system inhibitors and covid | 3 |
as a viral functional | 3 |
of the glomerular filtration | 3 |
in metabolic and inflammatory | 3 |
patients with hypertension and | 3 |
is activated by angii | 3 |
chronic pulmonary disease is | 3 |
activation of the protective | 3 |
these data suggest that | 3 |
m a n u | 3 |
that aceis and arbs | 3 |
of human angiotensin i | 3 |
increased risk of mortality | 3 |
regulators for bone metabolism | 3 |
of sky and sky | 3 |
of angiotensin ii in | 3 |
to those of ang | 3 |
signaling in the vasculature | 3 |
activation of circulating or | 3 |
ii receptor subtypes in | 3 |
introduction of renin inhibitors | 3 |
while the abundance of | 3 |
in patients with pulmonary | 3 |
of the map kinase | 3 |
entry and its immune | 3 |
the level of ang | 3 |
angiotensin system be withdrawn | 3 |
significant difference with regards | 3 |
authors declare no conflict | 3 |
peptides by human angiotensin | 3 |
expression of cd in | 3 |
in times of covid | 3 |
proteins of severe acute | 3 |
is an open access | 3 |
is available to authorized | 3 |
to be mediated through | 3 |
clinical trial of recombinant | 3 |
for patients with covid | 3 |
highly expressed in the | 3 |
pressure in the spontaneously | 3 |
between gut microbiota and | 3 |
related to respiratory collapse | 3 |
of at r and | 3 |
and its association with | 3 |
elevation of blood pressure | 3 |
of an ace inhibitor | 3 |
in the control of | 3 |
ace mrna expression and | 3 |
withdrawn in patients with | 3 |
high levels of ace | 3 |
allele was associated with | 3 |
mmol l which is | 3 |
of the ras is | 3 |
effect of aceis arbs | 3 |
ace is a carboxypeptidase | 3 |
in the present study | 3 |
in the human heart | 3 |
affect the kidneys directly | 3 |
activated protein kinase in | 3 |
release of vasopressin from | 3 |
smooth muscle cells via | 3 |
may contribute to the | 3 |
to specific receptors on | 3 |
either ace inhibitors or | 3 |
mediated ace shedding in | 3 |
ace has emerged as | 3 |
converting enzyme suppresses pathological | 3 |
profound loss of the | 3 |
ventricular fibrillation has been | 3 |
in the prevention and | 3 |
induced lung injury in | 3 |
through activation of the | 3 |
play upstream roles in | 3 |
of middle east respiratory | 3 |
amino acid from the | 3 |
and cardiovascular effects of | 3 |
production of nitric oxide | 3 |
the glomerular slit diaphragm | 3 |
chinese national health commission | 3 |
on blood pressure and | 3 |
and angiotensin ii type | 3 |
pulmonary arterial hypertension a | 3 |
a new member of | 3 |
demonstrate that ras l | 3 |
of the ras which | 3 |
in the role of | 3 |
the implications for the | 3 |
of pneumonia associated with | 3 |
at high risk of | 3 |
use of acei arb | 3 |
and the activation of | 3 |
role of the ras | 3 |
is also found in | 3 |
a homologue of ace | 3 |
virus entering host cells | 3 |
the n domain of | 3 |
throughout the gastrointestinal tract | 3 |
is mediated by the | 3 |
endoplasmic reticulum stress and | 3 |
is responsible for the | 3 |
ras in cardiovascular disease | 3 |
ace as the receptor | 3 |
angiotensin type i receptor | 3 |
to the pathogenesis of | 3 |
inflammation and oxidative stress | 3 |
in patients with acute | 3 |
a potential target for | 3 |
are patients with hypertension | 3 |
spike proteins of severe | 3 |
activate signal transduction pathways | 3 |
and reactive oxygen species | 3 |
converting enzyme in diabetic | 3 |
hypokalaemia compared to those | 3 |
infusion of ang ii | 3 |
risk of death in | 3 |
type receptor and the | 3 |
of at r expression | 3 |
stress likely play upstream | 3 |
the innate immune response | 3 |
degradation of angiotensin ii | 3 |
human recombinant ace reduces | 3 |
growth of cardiac myocytes | 3 |
association with the use | 3 |
medical treatment expert group | 3 |
fibrosis induced by ccl | 3 |
this is a key | 3 |
exerts its actions via | 3 |
has been detected in | 3 |
at r has been | 3 |
all the components required | 3 |
of oxidative stress and | 3 |
binds to the mas | 3 |
ratio of kidney weight | 3 |
the effect of angiotensin | 3 |
expressed at a moderate | 3 |
of spontaneously hypertensive rats | 3 |
and er stress likely | 3 |
not be used in | 3 |
been shown to upregulate | 3 |
was used to detect | 3 |
hypertension and cardiovascular diseases | 3 |
used to detect the | 3 |
which may explain the | 3 |
which cells were pretreated | 3 |
inhibits growth of cardiac | 3 |
stimulation of at receptors | 3 |
the impact of the | 3 |
expression in lung tumor | 3 |
is also associated with | 3 |
ace ace balance is | 3 |
mortality and disease severity | 3 |
of the weight of | 3 |
epub ahead of print | 3 |
reactive oxygen species and | 3 |
a significant reduction of | 3 |
cardiac pathology in covid | 3 |
in the apoe knockout | 3 |
has been demonstrated to | 3 |
role of nep in | 3 |
membrane in order to | 3 |
of the gut microbiota | 3 |
revision of ventilatory support | 3 |
in combination with the | 3 |
a prospective cohort study | 3 |
have higher levels of | 3 |
angiotensin ii receptor antagonists | 3 |
ii in the heart | 3 |
hypertensive rats angiotensin ii | 3 |
a type i transmembrane | 3 |
acute lung injury by | 3 |
treatment with at r | 3 |
has not been reported | 3 |
there is evidence of | 3 |
which is thought to | 3 |
fibrosis and oxidative stress | 3 |
in the aorta of | 3 |
that were limited to | 3 |
is not surprising that | 3 |
in the brains of | 3 |
statistically significant after correction | 3 |
the presence of an | 3 |
after the antibiotic intervention | 3 |
for those with myocardial | 3 |
the balance of the | 3 |
unclear if this is | 3 |
but not angiotensin ii | 3 |
and evolution of coronavirus | 3 |
angiotensin ii angiotensin ii | 3 |
in a family with | 3 |
l which is the | 3 |
the ras have been | 3 |
insensitive carboxypeptidase a novel | 3 |
the at receptor in | 3 |
the role of neprilysin | 3 |
severe critical illness in | 3 |
enzyme in brain tissue | 3 |
intrinsic proinflammatory signaling in | 3 |
significant after correction for | 3 |
of the unfolded protein | 3 |
in patients with portal | 3 |
and those with hypertension | 3 |
k and map k | 3 |
be generated from ang | 3 |
to be taken into | 3 |
is available regarding the | 3 |
at the time of | 3 |
in lung tumor cells | 3 |
and apoptosis in podocytes | 3 |
sky was sensitive to | 3 |
with more severe disease | 3 |
and ang ii are | 3 |
there is evidence for | 3 |
in the bile duct | 3 |
aerosolization of viral particles | 3 |
patients with chronic heart | 3 |
angiotensin receptor blockers have | 3 |
to activate signal transduction | 3 |
the downregulation of ace | 3 |
genetic ace deficiency accentuates | 3 |
c r i p | 3 |
outcomes among patients hospitalized | 3 |
seen in patients with | 3 |
and its immune cross | 3 |
proximal metaphysis of tibia | 3 |
are associated with the | 3 |
on liver fibrosis in | 3 |
upregulation of hepatic angiotensin | 3 |
in favor of the | 3 |
in maintaining the balance | 3 |
feedback mechanism in the | 3 |
of in situ immune | 3 |
have been proposed to | 3 |
have been attributed to | 3 |
the risk of cancer | 3 |
in the lung through | 3 |
there is evidence that | 3 |
by a variety of | 3 |
which is associated with | 3 |
the permeability of the | 3 |
of coronavirus spike proteins | 3 |
at r and a | 3 |
mediated pathophysiology in cvds | 3 |
a decoy peptide corresponding | 3 |
characterization of spike glycoprotein | 3 |
of ace inhibitors or | 3 |
blood pressure regulation and | 3 |
attenuates downregulation of angiotensin | 3 |
which was associated with | 3 |
hypertension in transgenic rats | 3 |
the regulation of captopril | 3 |
the effects of ras | 3 |
outcomes in subjects with | 3 |
in the ace and | 3 |
from the plasma membrane | 3 |
aceis arbs compared to | 3 |
these drugs in covid | 3 |
erk and p mapk | 3 |
in a state of | 3 |
cardiac myocytes through activation | 3 |
the physiological and pathophysiological | 3 |
effects in the cardiovascular | 3 |
the ras in lung | 3 |
rats effect of angiotensin | 3 |
several lines of evidence | 3 |
type receptor in human | 3 |
found to be highly | 3 |
with the dm group | 3 |
of protein kinase b | 3 |
the amount of ang | 3 |
of the central nervous | 3 |
roles in the ras | 3 |
ras inhibitors in covid | 3 |
the function of the | 3 |
transforming signal transduction pathways | 3 |
of the yeast pdr | 3 |
treatment expert group for | 3 |
we propose that covid | 3 |
and diabetes mellitus at | 3 |
mediated virus entering host | 3 |
indirectly via proteolytic processing | 3 |
model of type diabetes | 3 |
effects of aceis and | 3 |
as a homeostatic regulator | 3 |
a pilot clinical trial | 3 |
length human ace in | 3 |
the main effector of | 3 |
the ras system is | 3 |
in wuhan clinical course | 3 |
in the medical literature | 3 |
of trabecular bone at | 3 |
blood flow and oxygenation | 3 |
syndrome during mechanical ventilation | 3 |
to be a potent | 3 |
a r and at | 3 |
in ace null mice | 3 |
with chronic kidney disease | 3 |
of the discovery of | 3 |
in pancreatic cancer cells | 3 |
on vascular smooth muscle | 3 |
proinflammatory signaling in podocytes | 3 |
in patients with obstructive | 3 |
the number of x | 3 |
the at r has | 3 |
of ventilatory support choices | 3 |
of ace due to | 3 |
patients with heart failure | 3 |
the e protein of | 3 |
in addition to an | 3 |
has been suggested to | 3 |
of a large number | 3 |
system be withdrawn in | 3 |
aberrant renin angiotensin system | 3 |
as a target for | 3 |
not lead to a | 3 |
the at receptor can | 3 |
of inhibitors of the | 3 |
it has been previously | 3 |
into the tubular lumen | 3 |
as a novel target | 3 |
actions of angiotensin ii | 3 |
that ang ii is | 3 |
with pulmonary arterial hypertension | 3 |
in myocardial ischemia reperfusion | 3 |
clinical characteristics of cases | 3 |
respect to early anticoagulation | 3 |
on renal function in | 3 |
ace by the spike | 3 |
different definitions of severe | 3 |
generation of ang ii | 3 |
mechanical stress and the | 3 |
type ii transmembrane serine | 3 |
accentuates vascular inflammation and | 3 |
human ace structure of | 3 |
the protective effects of | 3 |
although it has been | 3 |
of the three groups | 3 |
group compared with that | 3 |
an angiotensin ii type | 3 |
a significantly reduced risk | 3 |
of protein kinase c | 3 |
patients with cardiovascular disease | 3 |
is regulated by some | 3 |
patients with pulmonary arterial | 3 |
a disintegrin and metalloprotease | 3 |
deposition of extracellular matrix | 3 |
mediates diabetic renal injury | 3 |
to be present in | 3 |
role of neutral endopeptidase | 3 |
angiotensin system blockade on | 3 |
hypertension in patients with | 3 |
for bone metabolism in | 3 |
evolution of coronavirus spike | 3 |
diabetes infected with covid | 3 |
sodium and water reabsorption | 3 |
blood pressure elevation and | 3 |
patients with essential hypertension | 3 |
formation of ang i | 3 |
cells of the kidney | 3 |
compared with that in | 3 |
of angiotensin ii with | 3 |
the formation of in | 3 |
ang i into ang | 3 |
the complexity of the | 3 |
which are associated with | 3 |
inflammation and atherosclerosis in | 3 |
such as diabetes mellitus | 3 |
the use of either | 3 |
outcomes between acei arb | 3 |
a wide array of | 3 |
in china clinical characteristics | 3 |
of arbs and acei | 3 |
alveolar epithelial cell apoptosis | 3 |
with at r blockers | 3 |
of spike glycoprotein of | 3 |
provided adjusted estimates for | 3 |
cells were pretreated with | 3 |
use of ace inhibitors | 3 |
and function of podocytes | 3 |
is known to cause | 3 |
to kill tumor cells | 3 |
adjusted estimates for severe | 3 |
by the spike protein | 3 |
in the cirrhotic liver | 3 |
for prevention and treatment | 3 |
formation of in situ | 3 |
of ace as the | 3 |
an experimental model of | 3 |
specific intercellular adhesion molecule | 3 |
on virus entry and | 3 |
the proteolytic cleavage of | 3 |
is the value required | 3 |
acei arb was non | 3 |
round of integrative transformation | 3 |
are a number of | 3 |
blockers and the covid | 3 |
activation promotes antithrombotic activity | 3 |
enzyme suppresses pathological hypertrophy | 3 |
induced reactive oxygen species | 3 |
relationship between gut microbiota | 3 |
syndrome coronavirus spike protein | 3 |
and the at r | 3 |
inflammation in patients with | 3 |
the ratio of kidney | 3 |
in this study was | 3 |
may account for the | 3 |
has been described as | 3 |
by the carboxypeptidase ace | 3 |
the tmprss cleavage site | 3 |
inhibition of ang ii | 3 |
flow and oxygenation in | 3 |
upstream roles in angii | 3 |
between men and women | 3 |
reabsorbed in the medullary | 3 |
gene and protein expression | 3 |
ventricular dysfunction in myocardial | 3 |
in animal models and | 3 |
increase of ang ii | 3 |
and the immune system | 3 |
neutral amino acids in | 3 |
the importance of the | 3 |
deeper understanding of the | 3 |
and clinical characteristics of | 3 |
of the ras by | 3 |
converting enzyme inhibitory peptides | 3 |
and smooth muscle cells | 3 |
in experimental biliary fibrosis | 3 |
enzyme in the late | 3 |
may be attributed to | 3 |
the context of the | 3 |
under high glucose conditions | 3 |
ii in vascular smooth | 3 |
coronavirus pneumonia in wuhan | 3 |
has a role in | 3 |
and revision of ventilatory | 3 |
increased risk for covid | 3 |
in the late phase | 3 |
of angiotensin receptor blockers | 3 |
dm group was significantly | 3 |
region for nonproteolytic activation | 3 |
in the medullary collecting | 3 |
and characterization of a | 3 |
ang ii can also | 3 |
available to authorized users | 3 |
the apoe knockout mouse | 3 |
blockade and risk of | 3 |
wuhan clinical course and | 3 |
diabetes mellitus at increased | 3 |
role for at r | 3 |
to the ace receptor | 3 |
be one of the | 3 |
correlated with the exposure | 3 |
the ace receptor is | 3 |
in addition to systemic | 3 |
pulmonary blood flow and | 3 |
has been shown that | 3 |
value required for those | 3 |
has been associated with | 3 |
has been implicated in | 3 |
converting enzyme in acute | 3 |
mrna and protein expression | 3 |
no significant difference in | 3 |
the medullary collecting duct | 3 |
human ace in complex | 3 |
circulating or local ras | 3 |
nep was reported to | 3 |
of ras inhibitors in | 3 |
expert group for covid | 3 |
observed no significant association | 3 |
under the stimulation of | 3 |
high expression of ace | 3 |
role in the development | 3 |
diabetes and cardiovascular disease | 3 |
response to high glucose | 3 |
middle cerebral artery occlusion | 3 |
the late phase of | 3 |
we systematically reviewed the | 3 |
that there was a | 3 |
to those with hyperkalaemia | 3 |
of the actin cytoskeleton | 3 |
the incidence of ventricular | 3 |
of ventricular dysfunction in | 3 |
which is the value | 3 |
did not differ between | 3 |
typical acute respiratory distress | 3 |
characterization of renal angiotensin | 3 |
clinical outcomes in subjects | 3 |
phase ii clinical trials | 3 |
the reninangiotensin system and | 3 |
the transtubular potassium gradient | 3 |
it is interesting to | 3 |
by removing the c | 3 |
reports have demonstrated that | 3 |
the modulation of captopril | 3 |
we suggest that nep | 3 |
angiotensin system inhibitors in | 3 |
and the united states | 3 |
level of ang ii | 3 |
electrosurgical and ultrasonic devices | 3 |
receptor blockers and angiotensin | 3 |
th anniversary of the | 3 |
e protein of avian | 3 |
of the ras receptors | 3 |
acid transporter b at | 3 |
differences in disease severity | 3 |
a deeper understanding of | 3 |
for the novel coronavirus | 3 |
of aceis arbs compared | 3 |
induced vascular senescence and | 3 |
endothelial and smooth muscle | 3 |
a compensatory increase in | 3 |
does not lead to | 3 |
transmembrane domain of the | 3 |
with hypokalaemia compared to | 3 |
system in cardiovascular disease | 3 |
at risk of severe | 3 |
with ace inhibitors and | 3 |
the discovery of the | 3 |
the online version of | 3 |
pathogenesis of severe acute | 3 |
injury in patients with | 3 |
pilot clinical trial of | 3 |
peptide corresponding to the | 3 |
states such as diabetes | 3 |
is a receptor for | 3 |
of randomised controlled trials | 3 |
of the ras axis | 3 |
to the disruption of | 3 |
in situ immune complexes | 3 |
the involvement of the | 3 |
from the use of | 3 |
treated with slgt inhibitors | 3 |
vascular endothelial and smooth | 3 |
and intrarenal ang ii | 3 |
is due to the | 3 |
a homeostatic regulator of | 3 |
the at receptor gene | 3 |
should inhibitors of the | 3 |
smooth muscle cell senescence | 3 |
acei arb relative to | 3 |
effects of ras blockade | 3 |
the results of the | 3 |
is then cleaved by | 3 |
that there is no | 3 |
with chronic heart failure | 3 |
decoy peptide corresponding to | 3 |
in the nucleus tractus | 3 |
thought to be the | 3 |
an acei arb relative | 3 |
the dm group compared | 3 |
incidence of ventricular fibrillation | 3 |
sex differences in immune | 3 |
with mortality among patients | 3 |
high level of expression | 3 |
amino acid transporter b | 3 |
is a type i | 3 |
antithrombotic effect of angiotensin | 3 |
new roles in inflammation | 3 |
china medical treatment expert | 3 |
of pathological cardiac hypertrophy | 3 |
arbs and severe critical | 3 |
ii receptor blockers in | 3 |
diagnostic and therapeutic intervention | 3 |
that of carboxypeptidase a | 3 |
risk of mortality and | 3 |
u s c r | 3 |
has been identified in | 3 |
blood pressure control and | 3 |
the introduction of renin | 3 |
proven to be effective | 3 |
late phase of ventricular | 3 |
role of the ace | 3 |
treatment of patients with | 3 |
the rate of ang | 3 |
generation of reactive oxygen | 3 |
ncov spike in the | 3 |
in order to determine | 3 |
minimum distance from the | 3 |
at r or masr | 3 |
metabolism of ang ii | 3 |
of the ras have | 3 |
of diabetic nephropathy by | 3 |
ras is activated in | 3 |
with or without hypertension | 3 |
activation of nadph oxidase | 3 |
fibrillation has been shown | 3 |
the pi k pathway | 3 |
vasopressin from the rat | 3 |
ii transmembrane serine proteases | 3 |
play a key role | 3 |
a reduced risk of | 3 |
pathways of the renin | 3 |
ii by aminopeptidase a | 3 |
be taken into account | 3 |
as it relates to | 3 |
are not required for | 3 |
converting enzyme by the | 3 |
over the last years | 3 |
and acute kidney injury | 3 |
cleavage of ang i | 3 |
nicotinamide adenine dinucleotide phosphate | 3 |
a typical acute respiratory | 3 |
in the metabolism of | 3 |
from ang ii to | 3 |
production and facilitates viral | 3 |
ncov on the epithelial | 3 |
levels are associated with | 3 |
the active site cleft | 3 |
protective role of ace | 3 |
phase of ventricular dysfunction | 3 |
virus entry and its | 3 |
the level of expression | 3 |
patients at high risk | 3 |
the two axes of | 3 |
dysfunction in myocardial infarcted | 3 |
hf with preserved ejection | 3 |
arb relative to the | 3 |
the novel coronavirus from | 3 |
fluid and electrolyte absorption | 3 |
risk of severe or | 3 |
pressure and renal function | 3 |
senescence of vascular smooth | 3 |
clinical characteristics of covid | 3 |
the catalytic activity of | 3 |
converting enzyme inhibitor on | 3 |
a novel therapeutic target | 3 |
there is increasing evidence | 3 |
the severity of the | 3 |
in an experimental model | 3 |
ang ii to the | 3 |
the weight of the | 3 |
given that ace is | 3 |
ace functions as a | 3 |
and an increase in | 3 |
was significantly associated with | 3 |
ang ii by aminopeptidase | 3 |
the antithrombotic effect of | 3 |
the explanation for this | 3 |
subjects with diabetes infected | 3 |
the value required for | 3 |
levels in experimental biliary | 3 |
severity or risk of | 3 |
with ace related multi | 3 |
therapeutic target for cardiovascular | 3 |
one of the major | 3 |
differ between normal lung | 3 |
patients with severe acute | 3 |
of mortality in covid | 3 |
of studies that provided | 3 |
fulminant hypertension in transgenic | 3 |
a potential pharmacological candidate | 3 |
reproduction in any medium | 3 |
have a greater role | 3 |
with lower risk of | 3 |
cleaved by ace to | 3 |
no obvious feedback activation | 3 |
studies that included hypertensive | 3 |
infarction increases ace expression | 3 |
and the ratio of | 3 |
that there may be | 3 |
underrepresented in the group | 3 |
significantly reduced risk of | 3 |
was digested with aatii | 3 |
the secretion of renin | 3 |
it was not until | 3 |
and apoptosis in the | 3 |
mental retardation and epilepsy | 3 |
heart failure with reduced | 3 |
length human ace structure | 3 |
compared to ras l | 3 |
potential effect of captopril | 3 |
of at r promotes | 3 |
ace mrna and protein | 3 |
pathological changes in the | 3 |
converting enzyme in experimental | 3 |
a large body of | 3 |
of renin angiotensin system | 3 |
er stress likely play | 3 |
by the spike proteins | 3 |
of prr in the | 3 |
if this is a | 3 |
induced senescence in vascular | 3 |
r and masr agonists | 3 |
recombinant ace reduces the | 3 |
be closely related to | 3 |
is also involved in | 3 |
the th anniversary of | 3 |
a small gtpase rac | 3 |
angiotensin system blockers and | 3 |
expression of angiotensin ii | 3 |
with the exposure time | 3 |
the development of dn | 3 |
is a negative regulator | 3 |
in human vascular smooth | 3 |
that inhibition of the | 3 |
were randomly divided into | 3 |
vascular inflammation and atherosclerosis | 3 |
enalapril attenuates downregulation of | 3 |
treatment of cardiovascular disease | 3 |
circular and longitudinal muscle | 3 |
for nonproteolytic activation of | 3 |
enzyme in acute respiratory | 3 |
the experiments to test | 2 |
mechanism in acute kidney | 2 |
gene i d polymorphism | 2 |
and the phenotype alterations | 2 |
a baculovirus expression system | 2 |
unprecedented global morbidity and | 2 |
of angiotensin iii in | 2 |
original studies that provided | 2 |
not increase the risk | 2 |
has been suggested by | 2 |
mas receptor axis is | 2 |
of a duplicated gene | 2 |
pathogenic actions of angiotensin | 2 |
hospital death of patients | 2 |
inhibition attenuates the progression | 2 |
role against cardiovascular events | 2 |
precipitated our interest in | 2 |
but is also found | 2 |
an important stress hormone | 2 |
of cellular senescence via | 2 |
an overly activated ras | 2 |
at r agonist c | 2 |
of the rate of | 2 |
they are responsible for | 2 |
blood pressure and exploratory | 2 |
an arb or an | 2 |
are new opportunities to | 2 |
sarcoidosis and other granulomatous | 2 |
coronavirus modulation of myocardial | 2 |
instead only the association | 2 |
with cardiovascular disease and | 2 |
acute respiratory syndrome than | 2 |
results in decreased expression | 2 |
arbs reduce lung cancer | 2 |
in ras wt samples | 2 |
and the dm ab | 2 |
of the caax box | 2 |
natural stem cell regulator | 2 |
the virus and the | 2 |
microbiota and ras activation | 2 |
in mice the angiotensin | 2 |
model of hypertension derived | 2 |
have shown that in | 2 |
engineered human tissues using | 2 |
may mean that senescence | 2 |
interventions are not directed | 2 |
activation and abrogated the | 2 |
propria mesenchymal cells and | 2 |
receptor antagonist candesartan as | 2 |
been identified as being | 2 |
cirrhosis and portal hypertension | 2 |
postmenopausal females in turn | 2 |
and er stress are | 2 |
regarding the contribution of | 2 |
but there was no | 2 |
tt region from pyes | 2 |
effects and clinical implications | 2 |
both in vitro and | 2 |
have the potential to | 2 |
polymorphism further support the | 2 |
therapeutic agents in covid | 2 |
reveals the potential risk | 2 |
which serves as the | 2 |
located on the x | 2 |
receptor binding domain of | 2 |
intraperitoneally injected with streptozotocin | 2 |
for angiotensin converting enzyme | 2 |
the treatment of human | 2 |
cleaves angii and ang | 2 |
if targeted to the | 2 |
and diseases are still | 2 |
of in vitro and | 2 |
in the face of | 2 |
are not technically separated | 2 |
angiotensinogen to ang i | 2 |
been considered to be | 2 |
genes for two enzymes | 2 |
the coexistence of inherited | 2 |
partial pressure of oxygen | 2 |
into the systemic circulation | 2 |
different extents of adjustment | 2 |
towards the pathophysiology of | 2 |
with a modulation of | 2 |
previous studies have shown | 2 |
the authors concluded that | 2 |
activation of the intrarenal | 2 |
and blood cancer cells | 2 |
expression ratio of osteoprotegerin | 2 |
in rats angiotensin ii | 2 |
research on the potential | 2 |
patients with t dm | 2 |
are the highest in | 2 |
and receptor activator of | 2 |
at and the at | 2 |
at r and healthspan | 2 |
exceptions and the exact | 2 |
ros and results in | 2 |
enzyme protein expression by | 2 |
ras actions including cell | 2 |
likely to have hypertension | 2 |
blood pressure in transgenic | 2 |
drugs and risk of | 2 |
chloride intracellular channel a | 2 |
reiterating that we need | 2 |
we and others have | 2 |
high mobility group box | 2 |
enhancement in the activity | 2 |
blockade on a new | 2 |
pathway in response to | 2 |
drugs used in co | 2 |
mice lacking angiotensin ii | 2 |
an open access article | 2 |
diabetic retinopathy in mice | 2 |
akita or akita mice | 2 |
direct endothelial cell damage | 2 |
by angii was observed | 2 |
with elevated plasma bacterial | 2 |
blood pressure elevation in | 2 |
acute lung failure in | 2 |
of the ras was | 2 |
at the atomic level | 2 |
case series of patients | 2 |
of receptor recognition by | 2 |
might favor virus membrane | 2 |
an increase in benefit | 2 |
more sensitive to the | 2 |
to the late development | 2 |
angiotensin ii induces smooth | 2 |
new congenic model of | 2 |
of large gene lists | 2 |
authentic angiotensin ii in | 2 |
ameliorates cardiac dysfunction observed | 2 |
namely severe acute respiratory | 2 |
ace inhibitors or angiotensin | 2 |
lifespan can be extended | 2 |
mechanisms contributing to arterial | 2 |
office of minority health | 2 |
decrease the amount of | 2 |
in a decrease in | 2 |
in the golgi compartment | 2 |
or agonists of the | 2 |
ang ii and other | 2 |
which simulate human premature | 2 |
its influence in gastrointestinal | 2 |
ros production is activated | 2 |
of acute severe pneumonia | 2 |
permeability of the filtration | 2 |
podocyte injury and proteinuria | 2 |
with the progression of | 2 |
unexpected aspects of covid | 2 |
preferred reporting items for | 2 |
by interacting with the | 2 |
suggested in the at | 2 |
with one of the | 2 |
which may contribute to | 2 |
although the exact mechanism | 2 |
a treatment of covid | 2 |
that in senescence accelerated | 2 |
antagonists are the most | 2 |
patients with cvd and | 2 |
renin prorenin receptor prepared | 2 |
data that may be | 2 |
expression by human coronavirus | 2 |
glucose and lipid metabolism | 2 |
provided adjusted estimates and | 2 |
and clinical studies of | 2 |
for hypertension and other | 2 |
the therapeutic potential of | 2 |
key roles in the | 2 |
is mediated by tace | 2 |
excreted into the tubular | 2 |
we were also able | 2 |
of the exposed cohort | 2 |
the pathogenesis of glomerulosclerosis | 2 |
via integration with the | 2 |
used for the quality | 2 |
with the reduction of | 2 |
no specific recommendations are | 2 |
in normotensive lewis rats | 2 |
receptor might contribute by | 2 |
between the virus and | 2 |
full text free full | 2 |
of inherited predispositions or | 2 |
with severe liver disease | 2 |
ace is a zinc | 2 |
it was reasoned that | 2 |
immunologic effects of the | 2 |
management of patients with | 2 |
an in vivo study | 2 |
in human pulmonary arterial | 2 |
protective effects of the | 2 |
of ras blockade on | 2 |
angii was observed in | 2 |
that reported mortality outcomes | 2 |
renin receptors has made | 2 |
potential role in cardiac | 2 |
in keeping with this | 2 |
juxtaglomerular cells of the | 2 |
abrogated the downregulation of | 2 |
the extracellular space of | 2 |
and beyond the renin | 2 |
lifespan of our population | 2 |
genes homo sapiens kegg | 2 |
limited whereas the condition | 2 |
according to the assay | 2 |
that occur in the | 2 |
saci and the purified | 2 |
activation of the at | 2 |
ii type receptor agonist | 2 |
actions including cell growth | 2 |
angiotensinogen gene is expressed | 2 |
are more susceptible to | 2 |
the degree of proteinuria | 2 |
as well as il | 2 |
basis of receptor recognition | 2 |
funnel plot was used | 2 |
signaling events and whether | 2 |
likely to die from | 2 |
expression and activity of | 2 |
axis in inflammation and | 2 |
and endoplasmic reticulum stress | 2 |
term use of arb | 2 |
progression of podocyte injury | 2 |
patients with vascular disease | 2 |
ace and ace cooperate | 2 |
is in line with | 2 |
an appropriate level of | 2 |
the initial drug development | 2 |
immense threat to healthcare | 2 |
further towards the c | 2 |
the therapeutic role of | 2 |
the ace i d | 2 |
regulation of ace expression | 2 |
as a pharmaceutical target | 2 |
lead to increased capillary | 2 |
is an important complication | 2 |
through the apelin receptors | 2 |
worsens glomerular injury in | 2 |
with age in rodents | 2 |
different to almost all | 2 |
shown that ang ii | 2 |
the vascular system is | 2 |
studies are needed to | 2 |
role in a variety | 2 |
significant association between the | 2 |
renin to the recombinant | 2 |
by a combination of | 2 |
by grants from the | 2 |
care units with the | 2 |
of rat hepatic fibrosis | 2 |
map k serine threonine | 2 |
actions similar to those | 2 |
in the action of | 2 |
been reported to promote | 2 |
even intestinal ischaemia have | 2 |
of severe disease and | 2 |
terminus of ras proteins | 2 |
the ras raf mek | 2 |
system inhibitors with severity | 2 |
flt to gm plays | 2 |
one of the following | 2 |
and transfected the following | 2 |
with vascular disease or | 2 |
in inflammation and fibrosis | 2 |
been considered one of | 2 |
low level and its | 2 |
cell proliferation in the | 2 |
lung fibrosis by inhibiting | 2 |
number of physiological processes | 2 |
individuals with diabetes infected | 2 |
of both the sars | 2 |
renal and cardiac tissue | 2 |
mutation in a family | 2 |
be a new target | 2 |
pleiotropic regulator of the | 2 |
obesity while enhancing insulin | 2 |
in patients with vascular | 2 |
was significantly increased compared | 2 |
the trabecular bone area | 2 |
been encouraging to date | 2 |
relevance in the angii | 2 |
regulates the activity of | 2 |
from the gut microbiota | 2 |
with all the components | 2 |
pronounced in disease conditions | 2 |
recent advances in the | 2 |
environment is not sucient | 2 |
we have shown that | 2 |
found that the expression | 2 |
to icus of the | 2 |
to cells precipitated our | 2 |
and temporal changes of | 2 |
of the ace ectodomain | 2 |
for women than for | 2 |
higher mortality for invasively | 2 |
ace g a polymorphism | 2 |
that our model stimulates | 2 |
essential roles in autocrine | 2 |
degree of heterodimer assembling | 2 |
stress and the induction | 2 |
and nucleotide exchange activities | 2 |
permeability of the yeast | 2 |
more translational research is | 2 |
significantly increased compared with | 2 |
hypoxia and er stress | 2 |
the development of salt | 2 |
this study was referred | 2 |
been shown to impact | 2 |
society of european robotic | 2 |
terms and conditions of | 2 |
by a baculovirus expression | 2 |
cytokines and chemokines in | 2 |
that ras inhibitors may | 2 |
as an average of | 2 |
role for the renin | 2 |
to the proper lengths | 2 |
clinical and experimental evidence | 2 |
peptidoglycans enhancing systemic inflammation | 2 |
that pharmacological inhibition of | 2 |
international clinical trials registry | 2 |
ace in the heart | 2 |
ii in the plasma | 2 |
ace gene do not | 2 |
and or peptidoglycans enhancing | 2 |
diversity analysis was performed | 2 |
of hypertension and diabetes | 2 |
inducing muscle senescence via | 2 |
and inflammation in patients | 2 |
damage in several organs | 2 |
midas vsmc produce altered | 2 |
disease conditions with ras | 2 |
respiratory distress syndrome recombinant | 2 |
the destruction of alveoli | 2 |
their mutual expression levels | 2 |
from the genetic analysis | 2 |
constructed by replacing the | 2 |
in serum markers of | 2 |
expression of nephrin in | 2 |
ace expression at the | 2 |
play important roles in | 2 |
to the severe acute | 2 |
media that lacked uracil | 2 |
aect the ability of | 2 |
can be generated from | 2 |
development of hypertension in | 2 |
it may be useful | 2 |
acute hypoxic pulmonary vasoconstriction | 2 |
caused by ang ii | 2 |
entry and local pulmonary | 2 |
in engineered human tissues | 2 |
and arbs has been | 2 |
lines of evidence support | 2 |
role in the regulation | 2 |
in those infected with | 2 |
deficiency leads to enhanced | 2 |
and protects against diabetic | 2 |
human intestine luminal ace | 2 |
inflammatory responses in aged | 2 |
recent discovery of renin | 2 |
coated with rabbit a | 2 |
no evidence to abandon | 2 |
lung injury provides an | 2 |
system and its role | 2 |
the next round of | 2 |
protein levels and activity | 2 |
to increased capillary permeability | 2 |
mediated through several signaling | 2 |
bone as well as | 2 |
complexity of the ras | 2 |
the observation that the | 2 |
loss of ace increases | 2 |
accelerates maladaptive left ventricular | 2 |
cytokine profile related to | 2 |
the immune system and | 2 |
by ang ii and | 2 |
imbalance of the renin | 2 |
presence of heterogeneity in | 2 |
show instead only the | 2 |
at r biased agonists | 2 |
in glomerular endothelium glycocalyx | 2 |
expression and inflammation in | 2 |
of overstimulation of at | 2 |
entry into the host | 2 |
which has been shown | 2 |
cytokines such as tnf | 2 |
mediated by tace adam | 2 |
in glomerular filtration barrier | 2 |
muscle cell proliferation in | 2 |
system in heart failure | 2 |
and pathophysiology including vasoconstriction | 2 |
expression of angiotensin receptors | 2 |
plays a critical role | 2 |
generally counteracts the classical | 2 |
and ang i into | 2 |
vasoconstriction and increase blood | 2 |
its extracellular domain shedding | 2 |
the urgency to study | 2 |
cleavage of ace by | 2 |
mrna expression and activity | 2 |
the expression of b | 2 |
r or masr inhibits | 2 |
been examined in a | 2 |
potential risk of different | 2 |
organ damage of this | 2 |