keyword-pcr-cord


Introduction

This is a Distant Reader "study carrel", a set of structured data intended to help the student, researcher, or scholar use & understand a corpus.

This study carrel was created on 2021-05-25 by Eric Morgan <emorgan@nd.edu>. The carrel was created using the Distant Reader cord process, and the input was the result of a query applied to a local mirror of CORD, a data set of scholarly articles on the topic of COVID-19. The actual query was: keywords:pcr. The results of this query were saved in a cache and transformed into a set of plain text files. All of the analysis -- "reading" -- has been done against these plain text files. For example, a short narrative report has been created. This Web page is a more verbose version of that report.

All study carrels are self-contained -- no Internet connection is necessary to use them. Download this carrel for offline reading. The carrel is made up of many subdirectories and data files. The manifest describes each one in greater detail.

Size

There are 972 item(s) in this carrel, and this carrel is 8,006,474 words long. Each item in your study carrel is, on average, 11,553 words long. If you dig deeper, then you might want to save yourself some time by reading a shorter item. On the other hand, if your desire is for more detail, then you might consider reading a longer item. The following charts illustrate the overall size of the carrel.

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histogram of sizes
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box plot of sizes

Readability

On a scale from 0 to 100, where 0 is very difficult and 100 is very easy, the documents have an average readability score of 49. Consequently, if you want to read something more simplistic, then consider a document with a higher score. If you want something more specialized, then consider something with a lower score. The following charts illustrate the overall readability of the carrel.

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histogram of readability
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box plot of readability

Word Frequencies

By merely counting & tabulating the frequency of individual words or phrases, you can begin to get an understanding of the carrel's "aboutness". Excluding "stop words", some of the more frequent words include:

patients, pcr, cells, virus, study, using, results, cell, blood, samples, detection, used, disease, clinical, infection, time, positive, also, viral, respiratory, analysis, one, may, two, rt, human, methods, high, group, expression, dna, cases, treatment, based, viruses, assay, rna, gene, data, different, associated, specific, test, cd, control, protein, performed, covid, sars, however

Using the three most frequent words, the three files containing all of those words the most are The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians – Poster Session, Poster Session Abstracts, and Scientific Programme.

The most frequent two-word phrases (bigrams) include:

time pcr, nucleic acid, respiratory tract, chain reaction, pcr assay, polymerase chain, stem cell, acute respiratory, reverse transcription, time rt, respiratory viruses, mg kg, influenza virus, respiratory syndrome, pcr assays, gene expression, bone marrow, cell transplantation, cell lines, novel coronavirus, present study, viral rna, severe acute, blood donors, performed using, viral load, significantly higher, clinical samples, peripheral blood, clinical signs, control group, respiratory syncytial, whole blood, infectious diseases, syncytial virus, median age, cell culture, cord uid, doc id, risk factors, coronavirus disease, flow cytometry, virus infection, public health, influenza viruses, amino acid, significant difference, isothermal amplification, epithelial cells, ng ml

And the three file that use all of the three most frequent phrases are Advances in Directly Amplifying Nucleic Acids from Complex Samples Application of Molecular Diagnostic Techniques for Viral Testing, and Diagnostic tools for tackling febrile illness and enhancing patient management.

While often deemed superficial or sophomoric, rudimentary frequencies and their associated "word clouds" can be quite insightful:

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unigrams
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bigrams

Keywords

Sets of keywords -- statistically significant words -- can be enumerated by comparing the relative frequency of words with the number of times the words appear in an entire corpus. Some of the most statistically significant keywords in the carrel include:

pcr, sars, rna, dna, covid-19, patient, virus, cell, respiratory, study, result, detection, infection, university, method, disease, sample, hiv, hcv, rsv, lamp, ibv, hospital, elisa, group, protein, hrv, expression, china, assay, increase, gene, cov-2, test, ifn, conclusion, pedv, il-6, human, hbv, case, blood, system, dog, cat, mouse, level, influenza, hla, csf

And now word clouds really begin to shine:

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keywords

Topic Modeling

Topic modeling is another popular approach to connoting the aboutness of a corpus. If the study carrel could be summed up in a single word, then that word might be patients, and RNA and DNA Bacteriophages as Molecular Diagnosis Controls in Clinical Virology: A Comprehensive Study of More than 45,000 Routine PCR Tests is most about that word.

If the study carrel could be summed up in three words ("topics") then those words and their significantly associated titles include:

  1. patients - Physicians – Poster Session
  2. pcr - ACTUALIZACION DE LA DECLARACIÓN DE CONSENSO EN MEDICINA CRITICA PARA LA ATENCIÓN MULTIDISCIPLINARIA DEL PACIENTE CON SOSPECHA O CONFIRMACIÓN DIAGNÓSTICA DE COVID-19
  3. patients - Infektionen

If the study carrel could be summed up in five topics, and each topic were each denoted with three words, then those topics and their most significantly associated files would be:

  1. patients, blood, results - Physicians – Poster Session
  2. pcr, virus, detection - Original Article: Real time reverse transcription (RRT)‐polymerase chain reaction (PCR) methods for detection of pandemic (H1N1) 2009 influenza virus and European swine influenza A virus infections in pigs
  3. cells, cell, protein - Literature review of baseline information on non‐coding RNA (ncRNA) to support the risk assessment of ncRNA‐based genetically modified plants for food and feed
  4. covid, patients, sars - Infektionen
  5. en, el, expression - 21 Infecties, ziekte en zwangerschap

Moreover, the totality of the study carrel's aboutness, can be visualized with the following pie chart:

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topic model

Noun & Verbs

Through an analysis of your study carrel's parts-of-speech, you are able to answer question beyonds aboutness. For example, a list of the most frequent nouns helps you answer what questions; "What is discussed in this collection?":

patients, cells, virus, results, study, cell, samples, blood, detection, infection, time, disease, analysis, cases, methods, expression, treatment, viruses, group, data, assay, gene, protein, diagnosis, infections, days, test, dna, studies, method, control, years, levels, influenza, age, number, children, patient, system, use, risk, type, sample, mice, testing, reaction, amplification, assays, genes, response

An enumeration of the verbs helps you learn what actions take place in a text or what the things in the text do. Very frequently, the most common lemmatized verbs are "be", "have", and "do"; the more interesting verbs usually occur further down the list of frequencies:

used, showed, detect, including, based, performed, increased, comparing, associated, found, identifying, follows, reported, determine, test, develop, observed, suggests, obtained, cause, evaluated, provides, induced, reduce, confirms, contains, described, require, collected, treated, receive, indicate, isolated, infect, demonstrated, considered, occurs, relates, present, resulting, investigating, reveal, assess, analyzed, known, remaining, measure, expressing, led, produced

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nouns
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verbs

Proper Nouns

An extraction of proper nouns helps you determine the names of people and places in your study carrel.

PCR, RT, RNA, SARS, CoV-2, C, COVID-19, mg, T, A, University, DNA, CT, Fig, B, HSCT, China, C., S., el, Table, M, HCV, USA, ⁄, II, ELISA, E., M., L, Hospital, RSV, S, CF, HIV, Health, van, CoV, los, HBV, H1N1, B., GVHD, CMV, D, P., HLA, RBC, Germany, G

An analysis of personal pronouns enables you to answer at least two questions: 1) "What, if any, is the overall gender of my study carrel?", and 2) "To what degree are the texts in my study carrel self-centered versus inclusive?"

we, it, our, their, its, they, i, them, he, his, she, her, us, one, itself, themselves, your, you, him, my, mcr-9, me, ourselves, mg, himself, ours, clustalx, iga1, mrnas, imagej, p210bcr, ya, itma, herself, em, s, igg4, igfbp2, hmsh2, esat-6, thier, pcv2, p24ag, mutationtaster3, iigp1, igm/, igg1, https://doi.org/10.1101/2020.08, hent1, fusb

Below are words cloud of your study carrel's proper & personal pronouns.

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proper nouns
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pronouns

Adjectives & Verbs

Learning about a corpus's adjectives and adverbs helps you answer how questions: "How are things described and how are things done?" An analysis of adjectives and adverbs also points to a corpus's overall sentiment. "In general, is my study carrel positive or negative?"

clinical, positive, respiratory, viral, high, human, different, specific, negative, significant, real, non, acute, low, higher, first, molecular, severe, anti, new, diagnostic, present, single, important, lower, available, common, several, rapid, normal, similar, infectious, novel, multiple, immune, bacterial, total, chronic, many, median, large, small, early, possible, primary, nucleic, genetic, potential, inflammatory, healthy

also, however, well, respectively, significantly, therefore, previously, highly, recently, even, still, often, especially, currently, furthermore, prior, clinically, approximately, moreover, frequently, less, commonly, mainly, directly, usually, first, now, particularly, together, statistically, relatively, finally, potentially, least, later, additionally, generally, widely, subsequently, alone, rapidly, specifically, successfully, fully, rather, yet, interestingly, already, far, almost

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adjectives
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adverbs

Next steps

There is much more to a study carrel than the things outlined above. Use this page's menubar to navigate and explore in more detail. There you will find additional features & functions including: ngrams, parts-of-speech, grammars, named entities, topic modeling, a simple search interface, etc.

Again, study carrels are self-contained. Download this carrel for offline viewing and use.

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