trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	1384
the presence of	813
the development of	640
the role of	637
the expression of	617
in order to	486
the effect of	486
results suggest that	486
in this study	466
the effects of	459
the number of	444
the present study	427
cd t cells	420
we found that	410
in response to	397
in the presence	387
the use of	383
one of the	383
involved in the	381
cells in the	374
these results suggest	351
been shown to	345
role in the	323
it has been	309
in the present	293
a number of	292
is associated with	289
in the brain	288
the absence of	287
has been shown	280
to investigate the	278
a variety of	260
the pathogenesis of	254
the regulation of	253
central nervous system	250
expression of the	249
in contrast to	247
in patients with	246
in the mouse	244
the induction of	243
an increase in	242
the aim of	240
an important role	239
suggest that the	238
study was to	237
in addition to	231
results indicate that	230
due to the	229
we investigated the	228
the treatment of	227
the activation of	227
balb c mice	222
the production of	220
of this study	218
compared to the	215
we show that	214
have shown that	209
observed in the	208
data suggest that	208
on the other	207
based on the	204
mouse hepatitis virus	203
to study the	203
the formation of	203
c bl mice	203
a role in	202
in the rat	202
this study was	201
in vitro and	200
in the absence	200
found to be	198
is involved in	198
important role in	197
the other hand	196
well as the	196
found in the	193
the level of	193
part of the	192
cd and cd	190
as compared to	189
be involved in	185
to determine the	183
graduate school of	178
of the disease	177
changes in the	177
shown to be	175
of the mouse	174
increase in the	173
the immune system	173
was found to	173
cells of the	172
has not been	168
associated with the	168
was observed in	167
has been reported	165
and in vivo	164
in the liver	163
contribute to the	163
activation of the	163
analysis of the	163
and in the	161
to be a	161
school of medicine	160
there was no	160
in the lungs	160
the activity of	158
in the regulation	158
the central nervous	157
the control of	157
as a result	157
mice infected with	157
was used to	156
but not in	156
the generation of	155
the majority of	155
are involved in	154
a mouse model	153
mouse model of	153
cd t cell	152
in the lung	152
vitro and in	151
we conclude that	151
we examined the	151
according to the	149
the function of	148
play a role	148
neurons in the	148
the amount of	147
high levels of	146
there is a	145
such as the	145
were able to	143
in the pathogenesis	143
the ability of	143
can be used	142
the importance of	142
be used to	141
depending on the	140
the course of	139
detected in the	139
of the virus	138
in the development	137
these results indicate	135
is known to	134
aim of this	134
has also been	134
the influence of	133
have been shown	133
related to the	132
is based on	132
expressed in the	131
the release of	131
the most common	130
c bl j	130
is characterized by	130
of the human	129
a result of	129
differences in the	129
appears to be	128
t cells and	128
of the most	128
play an important	128
role of the	128
well as in	125
the lack of	125
most of the	125
tumor necrosis factor	125
is one of	125
of patients with	125
of the immune	125
virus infection in	124
known to be	124
levels of il	124
for the treatment	123
responsible for the	123
these data suggest	123
the t cell	123
resulted in a	123
to evaluate the	122
was associated with	122
were observed in	122
as a model	121
associated with a	121
a decrease in	121
there is no	121
severe acute respiratory	120
mhc class i	119
in combination with	119
the onset of	119
results show that	119
rats and mice	118
in the same	118
indicate that the	118
the study of	117
used as a	117
expression in the	117
of the rat	116
the levels of	115
were found to	115
acute respiratory syndrome	114
the immune response	114
t cells in	113
may contribute to	112
in terms of	112
our results suggest	111
the ability to	111
by flow cytometry	111
member of the	111
was detected in	111
showed that the	111
the small intestine	111
were treated with	110
the end of	110
are associated with	110
strains of mice	109
with respect to	109
in comparison to	109
thought to be	109
the impact of	108
in a mouse	108
the lungs of	108
t cell responses	108
have been reported	107
found that the	106
were used to	106
there was a	105
to assess the	105
are known to	105
is required for	105
of t cells	105
is thought to	104
the involvement of	104
activity of the	104
have also been	103
the mechanism of	103
present in the	103
considered to be	103
be associated with	103
of t cell	103
been reported to	102
is an important	102
been reported in	102
of cd t	102
when compared to	102
to be the	101
seems to be	100
the context of	100
was determined by	100
findings suggest that	100
data indicate that	100
had no effect	99
a series of	99
compared to control	99
no effect on	99
are able to	98
in which the	98
have been used	98
show that the	98
the frequency of	97
have not been	97
little is known	97
a model of	97
is mediated by	97
is known about	97
and cd t	96
t cell receptor	96
control of the	96
the severity of	96
the identification of	95
immune response to	95
regulation of the	95
their ability to	95
to play a	95
aim of the	95
in the hippocampus	95
in the control	94
effect on the	94
in the context	94
the time of	94
t cell activation	94
we have previously	94
it is not	93
present study was	93
the results of	93
similar to that	93
in the number	93
in the treatment	92
the administration of	92
in the central	92
mouse models of	92
in mice and	92
understanding of the	92
the fact that	92
may be a	91
of the brain	91
we analyzed the	91
to that of	90
effects of the	90
may also be	90
is essential for	90
region of the	90
members of the	90
seen in the	90
activity in the	90
in situ hybridization	89
can also be	89
a role for	89
this study we	89
respiratory syndrome coronavirus	89
been shown that	89
the cell surface	88
the spinal cord	88
is able to	88
similar to those	88
lymphocytic choriomeningitis virus	88
in the cns	88
in vivo and	88
is the most	88
in the small	88
to determine whether	87
by means of	87
some of the	87
a significant increase	87
were found in	87
to elucidate the	87
end of the	87
of the present	87
of cell death	87
a member of	86
a model for	86
in the human	86
we observed that	86
for the first	86
function of the	86
animal models of	86
the inhibition of	86
of the study	86
for the development	86
respiratory syncytial virus	86
been used to	86
appear to be	85
in the early	85
it is important	85
used in the	85
and can be	85
the molecular mechanisms	84
than in the	84
we have shown	84
the result of	84
is important to	84
in the adult	84
was shown to	84
we studied the	83
isolated from the	83
were detected in	83
the united states	83
were exposed to	83
infection in mice	83
the addition of	83
shown that the	83
dependent on the	83
we showed that	82
the plasma membrane	82
gd t cells	82
was found in	82
to be involved	82
significant increase in	82
with regard to	82
reactive oxygen species	81
in this model	81
demonstrated that the	81
polymerase chain reaction	81
be due to	81
a combination of	81
of mice with	81
because of the	81
the increase in	80
to understand the	80
in humanized mice	80
these findings suggest	80
the surface of	80
the percentage of	80
is expressed in	80
with or without	80
smooth muscle cells	80
the degree of	80
the inflammatory response	80
the risk of	80
have been identified	79
serum levels of	79
the detection of	79
which can be	79
in association with	78
supported by the	78
gene expression in	78
development of the	78
and function of	78
under the control	78
plays an important	77
characterization of the	77
university of tokyo	77
mice treated with	77
which is a	77
the basis of	77
was measured by	77
the cells were	76
to examine the	76
the process of	76
of these cells	76
at the same	76
development of a	76
at the time	76
the incidence of	76
male and female	76
levels in the	76
the in vivo	76
may be present	76
led to a	75
studies have shown	75
we demonstrate that	75
to identify the	75
due to a	75
the in vitro	75
the hypothesis that	75
the purpose of	75
an in vitro	75
may play a	74
in c bl	74
that can be	74
suggesting that the	74
was able to	74
is caused by	74
results demonstrate that	74
there were no	74
are susceptible to	74
is a major	73
were obtained from	73
the progression of	73
in a dose	73
was assessed by	73
did not affect	73
the first time	73
will be discussed	73
increased expression of	72
for up to	72
mouse and human	72
our results indicate	72
the analysis of	72
a crucial role	72
t h e	72
were subjected to	72
can be detected	72
have been described	72
regions of the	72
have demonstrated that	72
an animal model	72
we are currently	72
of mouse hepatitis	72
has been demonstrated	71
t cells were	71
that of the	71
and activation of	71
consistent with the	71
the interaction of	71
derived from the	71
to the development	71
revealed that the	71
in the first	71
of the two	70
national institute of	70
during the first	70
class i molecules	70
the type of	70
this work was	70
the respiratory tract	70
humanized mouse model	69
the mice were	69
the bone marrow	69
the oral cavity	69
h n pdm	69
compared with the	69
components of the	69
of the protein	69
we have recently	69
department of physiology	69
in the blood	69
as previously described	69
inhibition of the	69
response to the	68
in the expression	68
a subset of	68
t cells from	68
used for the	68
been associated with	68
the virus is	68
of the cell	68
have been developed	68
to analyze the	67
the contribution of	67
study of the	67
required for the	67
also known as	67
that have been	67
on the basis	67
of the mice	67
be found in	67
the efficacy of	67
for the study	67
in laboratory mice	67
are thought to	67
the distribution of	67
the control group	66
similar to the	66
this suggests that	66
increased in the	66
of the cd	66
national research council	66
of these genes	66
the loss of	66
was supported by	66
and found that	66
higher levels of	66
western blot analysis	66
expression of cd	66
has been used	66
decrease in the	65
in rats and	65
and may be	65
our results show	65
located in the	65
the response to	65
at room temperature	65
mice and rats	65
a panel of	65
suggests that the	65
for at least	65
morbidity and mortality	65
in the united	65
the existence of	65
at the end	64
reported to be	64
east respiratory syndrome	64
the site of	64
and in vitro	64
we were able	64
results in a	64
the rate of	64
immune responses in	64
in these mice	63
demonstrate that the	63
a critical role	63
associated with an	63
we have developed	63
depends on the	63
leads to a	63
followed by a	63
effect of the	63
middle east respiratory	63
of laboratory animals	63
is regulated by	62
was used as	62
of the central	62
infection in the	62
mice compared to	62
our data suggest	62
of mice and	62
the acute phase	62
a range of	62
to test the	62
of the same	62
was used for	62
of the small	62
were infected with	62
is due to	61
weeks of age	61
were isolated from	61
of laboratory mice	61
in guinea pigs	61
each of the	61
is a common	61
as a consequence	61
between the two	61
contributes to the	61
may lead to	61
increased levels of	61
only in the	61
as in the	61
the relationship between	61
bl j mice	61
the mechanisms of	61
of the t	60
mouse model for	60
the case of	60
our understanding of	60
insights into the	60
results in the	60
the extent of	60
were used as	60
contrast to the	60
may not be	60
approved by the	60
characterized by a	60
expression of il	60
was to investigate	60
the age of	60
in the heart	60
respiratory distress syndrome	60
university school of	60
virus of mice	60
were determined by	60
in the developing	60
in the case	60
the lamina propria	60
mice in the	60
as a potential	60
we hypothesized that	60
infection of the	60
the university of	59
presence of a	59
acts as a	59
is responsible for	59
effects on the	59
and expression of	59
could not be	59
in the spleen	59
production of il	59
of gene expression	59
the transcription factor	59
the growth of	59
before and after	58
the possibility that	58
can lead to	58
diagnosis is based	58
stimulation of the	58
up to days	58
on the surface	58
of the inflammatory	58
here we show	58
specific t cells	58
be related to	58
by the presence	58
were shown to	58
a reduction in	58
immune responses to	58
and c bl	58
the application of	58
we propose that	58
when compared with	58
of the host	58
the liver and	58
we found a	58
in immunodeficient mice	57
addition to the	57
results showed that	57
is important for	57
was induced by	57
its ability to	57
be used for	57
in t cell	57
a and b	57
the action of	57
in laboratory animals	57
the potential of	57
structure of the	57
will be presented	57
studies on the	57
to characterize the	57
specific cd t	57
a key role	57
the potential to	57
data show that	56
response in the	56
wide range of	56
in animal models	56
levels of the	56
we have identified	56
acute lung injury	56
been implicated in	56
t cell response	56
be detected in	56
antigen presenting cells	56
is considered to	56
the nature of	56
than that of	56
to those of	56
is dependent on	56
herpes simplex virus	56
has been suggested	56
influenza a virus	56
were measured by	56
likely to be	55
in balb c	55
be responsible for	55
of cd and	55
in humans and	55
comparison of the	55
in the serum	55
an increase of	55
of the animals	55
serve as a	55
and b cells	55
presence of the	55
on the cell	55
and has been	55
mutations in the	55
a total of	55
of the cells	55
no significant differences	55
the gastrointestinal tract	55
innate and adaptive	55
to clarify the	55
as assessed by	55
has been described	55
neural stem cells	55
in the stomach	55
the pathophysiology of	54
findings indicate that	54
be used as	54
a wide range	54
in line with	54
specific t cell	54
well as a	54
lesions in the	54
and that the	54
the combination of	54
may be involved	54
correlated with the	54
investigate the role	54
of influenza virus	54
referred to as	54
in immunocompetent mice	54
we hypothesize that	54
a period of	54
experimental infection of	53
compared to controls	53
can be induced	53
the most important	53
in mouse models	53
mechanism of action	53
a group of	53
known about the	53
are the most	53
is accompanied by	53
was confirmed by	53
for the detection	53
in both groups	53
has been proposed	53
suggested that the	53
in other organs	53
implicated in the	53
due to their	53
science and technology	53
university graduate school	53
the outcome of	53
materials and methods	53
from patients with	53
we used a	52
as early as	52
of the lung	52
it is possible	52
be used in	52
nitric oxide synthase	52
we observed a	52
in mice with	52
which may be	52
a reduction of	52
led to the	52
plasma levels of	52
presence or absence	52
one or more	52
may be used	52
human and mouse	52
the same time	52
a consequence of	52
in vitro studies	52
in t cells	52
was carried out	52
a major role	52
t and b	52
in the spinal	52
it can be	52
large number of	52
with the same	52
it was found	52
the binding of	52
was performed using	52
the concentration of	51
at least one	51
that in the	51
t cells are	51
inflammatory bowel disease	51
important for the	51
the recruitment of	51
are found in	51
many of the	51
been observed in	51
use of the	51
in relation to	51
the prevalence of	51
or absence of	51
in this process	51
based on a	51
data demonstrate that	51
it is also	51
and there is	51
of the first	51
b cells and	51
phase of the	51
it may be	51
in the study	51
the brain and	51
leading to the	51
to this end	51
work was supported	51
mediated by the	50
were incubated with	50
of the mucosa	50
we demonstrated that	50
we have found	50
west nile virus	50
influenza virus infection	50
crucial role in	50
the magnitude of	50
significant differences in	50
cell proliferation and	50
the size of	50
hla class i	50
cells from the	50
the animals were	50
animal model for	50
vivo and in	50
mesenteric lymph nodes	50
a concentration of	50
and it is	50
in comparison with	50
wild type mice	50
critical role in	50
the appearance of	50
are expressed in	50
in accordance with	49
none of the	49
did not show	49
and characterization of	49
a role of	49
expression levels of	49
animal models for	49
are similar to	49
in peripheral blood	49
the innate immune	49
occur in the	49
human immune system	49
we aimed to	49
to investigate whether	49
we have investigated	49
an inhibitor of	49
vascular smooth muscle	49
the results suggest	49
half of the	49
could be detected	49
hepatitis b virus	49
be induced by	49
nature of the	49
c and c	49
t cell proliferation	49
expression of a	49
humanized mouse models	49
responses in the	49
obtained from the	49
significantly reduced in	49
which has been	49
is a potent	49
difference in the	48
showed a significant	48
change in the	48
mrna and protein	48
because of their	48
cytotoxic t lymphocytes	48
of reactive oxygen	48
no significant difference	48
of the major	48
mice subjected to	48
reduction in the	48
of the il	48
are capable of	48
previously shown that	48
infection of mice	48
the pattern of	48
that it is	48
have previously shown	48
these data indicate	48
regulatory t cells	48
a set of	48
some of these	48
animal model of	48
this study is	48
by western blot	48
major role in	48
a dose of	48
for min at	48
day after inoculation	48
this effect was	48
leads to the	48
hyperplasia of the	48
is the first	48
rats treated with	48
course of the	48
are present in	48
in suckling mice	48
in transgenic mice	48
indicating that the	48
remains to be	47
acute respiratory distress	47
immune responses and	47
diseases such as	47
in some cases	47
were analyzed by	47
induced by the	47
by using the	47
may be associated	47
have to be	47
caused by a	47
to be more	47
the salivary glands	47
molecular mechanisms of	47
the potential for	47
in the kidney	47
of infected mice	47
the kinetics of	47
these results demonstrate	47
not affected by	47
is supported by	47
is critical for	47
laboratory animal medicine	47
in a model	47
the brains of	46
was also observed	46
the maintenance of	46
immune response in	46
it is a	46
rat and mouse	46
as determined by	46
blood mononuclear cells	46
mice immunized with	46
in the formation	46
is not a	46
was inhibited by	46
in regulation of	46
component of the	46
lesions of the	46
seem to be	46
investigated the effects	46
was not affected	46
a large number	46
in the ca	46
of infant mice	46
disease in mice	46
pharmakologie und toxikologie	46
of b cells	46
used to study	46
in a variety	46
we have demonstrated	46
was found that	46
at the level	46
models have been	46
indicated that the	46
a central role	46
essential for the	45
plays a role	45
compared to wild	45
adaptive immune responses	45
in the induction	45
of c bl	45
in cell culture	45
factors such as	45
we developed a	45
different types of	45
key role in	45
cells and the	45
percy and barthold	45
study is to	45
model to study	45
on day after	45
little or no	45
peripheral blood mononuclear	45
two types of	45
we suggest that	45
model for the	45
mice with the	45
p and p	45
clinical signs of	45
we have used	45
the proportion of	45
mice can be	45
the laboratory mouse	45
wide variety of	45
weight loss and	45
data not shown	45
of inflammatory cytokines	45
we compared the	44
that the expression	44
was expressed in	44
in a murine	44
are essential for	44
associated with increased	44
purpose of this	44
of proinflammatory cytokines	44
a wide variety	44
were performed in	44
any of the	44
to develop a	44
size of the	44
to explore the	44
in the thymus	44
clinical signs and	44
the capacity of	44
can result in	44
present study we	44
need to be	44
we report that	44
prevention and control	44
the occurrence of	44
also observed in	44
highly expressed in	44
in the peripheral	44
are considered to	44
surface of the	44
is necessary for	44
genes involved in	44
mechanisms involved in	44
during the course	44
is likely to	44
in the production	44
been suggested that	44
the presence or	44
the accumulation of	44
evaluation of the	44
innate immune response	44
of up to	44
of the c	43
the susceptibility of	43
of the anti	43
is observed in	43
is similar to	43
correlation between the	43
caused by the	43
administration of the	43
better understanding of	43
mice with a	43
the evaluation of	43
e l l	43
the modulation of	43
at least in	43
epidermal growth factor	43
needs to be	43
as a novel	43
to determine if	43
the relevance of	43
also been reported	43
is induced by	43
a family of	43
were seen in	43
were used for	43
hematopoietic stem cells	43
in case of	43
properties of the	43
the nlrp inflammasome	43
in the olfactory	43
investigated the effect	43
the interaction between	43
of the gene	43
especially in the	43
time course of	43
used as an	43
replication in the	43
significantly increased in	43
as measured by	43
its role in	43
in a number	43
the differentiation of	43
are responsible for	42
as shown in	42
transgenic mouse model	42
all of the	42
a decrease of	42
recent studies have	42
we have studied	42
binding to the	42
important roles in	42
amino acid sequence	42
that may be	42
accompanied by a	42
we also found	42
linked immunosorbent assay	42
alterations in the	42
mice were infected	42
were carried out	42
not associated with	42
and spinal cord	42
by using a	42
in the cell	42
are required for	42
mice have been	42
in this context	42
is not clear	42
has to be	42
parts of the	42
care and use	42
has been developed	42
mhc class ii	42
as compared with	42
important in the	42
vg vd t	42
on day p	42
of the different	42
was significantly reduced	42
used to determine	42
months of age	42
of the patients	42
the secretion of	42
cells in vitro	42
analysis revealed that	41
mice exposed to	41
of tcf l	41
believed to be	41
total number of	41
the form of	41
in the nasal	41
is the major	41
but it is	41
a transgenic mouse	41
significant difference in	41
conclude that the	41
to the cell	41
equine encephalitis virus	41
not in the	41
be accompanied by	41
due to an	41
proliferation and differentiation	41
in our study	41
in the bone	41
reduction of the	41
in the immune	41
infected with the	41
resulted in the	41
has been found	41
the possibility of	41
to the control	41
cells as well	41
was evaluated by	41
surface expression of	41
the proliferation of	41
in the mice	41
is present in	41
able to induce	41
that activation of	41
of our study	41
as indicated by	41
a significant reduction	41
t cell clones	41
have developed a	40
to a lesser	40
cytokines and chemokines	40
fold increase in	40
brain science institute	40
was induced in	40
inflammation in the	40
it should be	40
based on these	40
the range of	40
were measured in	40
was performed in	40
virus in the	40
human immunodeficiency virus	40
was to evaluate	40
were stained with	40
a n t	40
innate immune responses	40
activation in the	40
balb c and	40
involved in this	40
increase of the	40
mechanism by which	40
with a high	40
significant decrease in	40
should be considered	40
we have also	40
leading to a	40
and differentiation of	40
compared to those	40
was performed by	40
and on the	40
have been found	40
it is known	40
c e l	40
multiple organ failure	40
to infection with	40
cell death in	40
this is the	40
was significantly higher	40
of human disease	40
has shown that	40
has been observed	40
higher in the	40
of the total	40
b c f	40
insight into the	40
is a key	40
with that of	40
of the gastric	39
but not the	39
there is an	39
is believed to	39
a significant decrease	39
that there is	39
the cause of	39
resulting in a	39
h n virus	39
of the p	39
in the process	39
should not be	39
here we report	39
the olfactory bulb	39
cb infected mice	39
stages of the	39
was seen in	39
as described above	39
differences between the	39
patients with severe	39
for detection of	39
features of the	39
a pivotal role	39
the initiation of	39
cytokines such as	39
an immune response	39
have suggested that	39
different time points	39
specific for the	39
of the murine	39
of the receptor	39
days after the	39
in the last	39
learning and memory	39
of mice to	39
be caused by	39
in recent years	39
disruption of the	39
these results show	39
and t cell	39
the increase of	39
to increase the	39
transforming growth factor	39
mice that were	39
have found that	39
oxidative stress and	39
and development of	39
can be found	39
of the lesion	39
may have a	39
not appear to	39
for the generation	39
cells can be	39
of in vitro	39
a recent study	39
years of age	38
the changes in	38
cell lines and	38
be able to	38
h n influenza	38
are characterized by	38
at days post	38
it was shown	38
liver and spleen	38
studies showed that	38
but did not	38
order to determine	38
response to a	38
in the past	38
is composed of	38
both types of	38
central role in	38
be differentiated from	38
in mice is	38
regardless of the	38
for treatment of	38
the amino acid	38
type i ifn	38
but not by	38
to better understand	38
we tested the	38
of infection in	38
of inflammatory cells	38
were tested for	38
a mixture of	38
necessary for the	38
inbred strains of	38
is consistent with	38
lower respiratory tract	38
appeared to be	38
a better understanding	38
after treatment with	38
to that in	38
in the laboratory	37
to interact with	37
may be more	37
have investigated the	37
we focused on	37
was performed on	37
receptors in the	37
the rat and	37
immune system in	37
produced by the	37
from the same	37
our results demonstrate	37
disease caused by	37
for this purpose	37
lead to the	37
low levels of	37
significantly higher in	37
been described in	37
to have a	37
and dendritic cells	37
in these cells	37
the study was	37
the synthesis of	37
exposed to the	37
has been implicated	37
the brain of	37
which could be	37
capacity of the	37
to be an	37
the cerebral cortex	37
of the oral	37
the specificity of	37
gene expression of	37
the peripheral blood	37
of the infection	37
compared to wt	37
the nervous system	37
level of the	37
the numbers of	37
of a single	37
out of the	37
protective effect of	37
mice did not	37
infected with a	37
we measured the	37
to respond to	37
to test this	37
we investigated whether	37
in the plasma	37
due to its	37
significant increase of	37
for the induction	37
mrna expression of	37
modulation of the	37
mice and humans	37
in biomedical research	36
was no significant	36
examination of the	36
the capacity to	36
formation of the	36
in vivo studies	36
in vitro model	36
of the respiratory	36
a murine model	36
we could show	36
virus can be	36
of the intestinal	36
to the same	36
rats exposed to	36
on day and	36
in adult mice	36
are resistant to	36
been demonstrated in	36
of adult mice	36
was increased in	36
on the expression	36
use of a	36
has recently been	36
but also in	36
the gastric mucosa	36
been found to	36
specificity of the	36
for the presence	36
and days after	36
infiltration of the	36
to be associated	36
reported in the	36
is not known	36
characterized by the	36
lead to a	36
were detected by	36
which in turn	36
information on the	36
no difference in	36
be present in	36
which results in	36
of neurons in	36
the development and	36
astrocytes in the	36
evidence suggests that	36
is related to	36
be detected by	36
with and without	35
of the animal	35
the establishment of	35
analysis showed that	35
of a novel	35
mode of action	35
even in the	35
added to the	35
the stimulation of	35
memory t cells	35
mechanisms by which	35
we evaluated the	35
intraperitoneal injection of	35
damage to the	35
mechanism of the	35
cells with a	35
and to a	35
days of age	35
in the hippocampal	35
mouse and rat	35
in the activation	35
and bone marrow	35
and female mice	35
and lymph nodes	35
of humanized mice	35
could be a	35
prior to the	35
more susceptible to	35
can occur in	35
impact on the	35
may be due	35
the olfactory epithelium	35
murine hepatitis virus	35
they can be	35
formation in the	35
may be the	35
is crucial for	35
applied to the	35
their role in	35
of these two	35
determined by the	35
were significantly reduced	35
of type i	35
model for human	35
were significantly increased	35
not yet been	35
as evidenced by	35
one of these	35
of the stomach	35
upper respiratory tract	35
is found in	35
of the epithelium	35
the expression and	35
should be used	35
be one of	35
of the innate	35
of a mouse	35
of immune responses	34
and the other	34
after stimulation with	34
severity of the	34
mice were injected	34
carried out in	34
of immune cells	34
those of the	34
is seen in	34
the structure of	34
induction of the	34
treated with the	34
was accompanied by	34
in mice infected	34
induced by a	34
significantly reduced the	34
experiments were performed	34
cells with the	34
of the skin	34
up to weeks	34
elevated levels of	34
blood samples were	34
in vivo imaging	34
in the skin	34
to be important	34
than those of	34
similar results were	34
at a concentration	34
lymph nodes and	34
characteristics of the	34
b cells in	34
been identified as	34
in a similar	34
the results indicate	34
restricted to the	34
as part of	34
red blood cells	34
have been observed	34
mice in which	34
but does not	34
immunized via the	34
did not change	34
animal care and	34
at different time	34
was applied to	34
linked to the	34
to the brain	34
the brain parenchyma	34
a lack of	34
compared to that	34
atcf l ko	34
is a member	34
type i interferon	34
of the cellular	34
in the future	34
on the contrary	34
in vitro experiments	34
we have generated	34
were associated with	34
is activated by	34
were performed using	34
mucosa of the	34
as shown by	34
may result in	34
of the cns	34
examined the effects	34
were used in	34
we used the	34
programmed cell death	34
in the pathophysiology	34
the endoplasmic reticulum	34
we generated a	33
n pdm infection	33
was analyzed by	33
pivotal role in	33
that inhibition of	33
in wild type	33
is a highly	33
within the first	33
a protective role	33
close to the	33
we are now	33
be mediated by	33
many of these	33
layer of the	33
was followed by	33
this may be	33
high doses of	33
to reduce the	33
have been associated	33
portion of the	33
did not induce	33
damage in the	33
to inhibit the	33
cells derived from	33
in both the	33
to the virus	33
result of the	33
but not to	33
hepatitis virus infection	33
studies suggest that	33
the length of	33
previous studies have	33
infection in a	33
is possible that	33
human peripheral blood	33
which have been	33
the host immune	33
is necessary to	33
immune response and	33
was not observed	33
it is well	33
evidence for a	33
been found in	33
and treatment of	33
used in this	33
also found that	33
was increased by	33
mice were inoculated	33
act as a	33
of the genes	33
to address the	33
was isolated from	33
the amplitude of	33
in skeletal muscle	33
to address this	33
murine model of	33
be useful in	33
examined the effect	33
number of cells	33
of bone marrow	33
were stimulated with	33
mice were treated	32
in the form	32
might be a	32
i o n	32
included in the	32
bone marrow and	32
the collaborative cross	32
in the nucleus	32
the mouse and	32
to be used	32
development of new	32
not affect the	32
we determined the	32
has been identified	32
in nude mice	32
expression pattern of	32
the class i	32
of dendritic cells	32
with the development	32
results suggested that	32
the roles of	32
male wistar rats	32
been reported that	32
not observed in	32
of influenza a	32
the characterization of	32
of the lungs	32
results were obtained	32
b and t	32
were expressed in	32
spinal cord injury	32
we performed a	32
been identified in	32
particularly in the	32
and adaptive immune	32
of adhesion molecules	32
for use in	32
and release of	32
used to detect	32
in the cytoplasm	32
these data demonstrate	32
cellular and molecular	32
in severe cases	32
be considered as	32
c mice were	32
after the last	32
lower in the	32
could be used	32
are important for	32
expression level of	32
and loss of	32
cell responses in	32
is known that	32
by the use	32
protein kinase c	32
in view of	32
to define the	32
by treatment with	32
in the cerebellum	32
is difficult to	32
the isolation of	32
inflammatory response in	32
of the adult	32
n t i	32
significant reduction in	32
may have been	32
a marker of	32
the migration of	32
difference between the	32
peripheral blood lymphocytes	32
more than of	32
to compare the	32
in conjunction with	32
may be an	32
route of infection	32
flow cytometry and	32
samples were collected	32
mice may be	32
epithelium of the	32
in the primary	32
of the h	32
mg kg day	32
the reduction of	32
were positive for	32
our findings suggest	32
the ratio of	32
of severe acute	32
t i o	32
days after infection	32
leads to an	32
t cells was	32
to improve the	31
immune system and	31
presence of il	31
is used as	31
pneumonia virus of	31
was shown that	31
injected into the	31
was identified as	31
mice that are	31
cells within the	31
systemic inflammatory response	31
the diagnosis of	31
expression of genes	31
of which are	31
is produced by	31
investigated the role	31
human t cells	31
in mice by	31
the need for	31
memory b cells	31
the duration of	31
and t cells	31
with an increase	31
in the lamina	31
delta t cells	31
c bl and	31
previously reported that	31
in an animal	31
responses to the	31
transgenic mice expressing	31
treatment with the	31
in the brains	31
deletion of the	31
each of these	31
secretion of il	31
and maintenance of	31
the mechanisms underlying	31
the nasal cavity	31
of expression of	31
depend on the	31
of action of	31
during the early	31
investigate the effect	31
analysis was performed	31
of at least	31
of the experiment	31
the time course	31
roles in the	31
play important roles	31
major histocompatibility complex	31
majority of the	31
proteins involved in	31
not result in	31
c h hen	31
resulting in the	31
astrocytes and microglia	31
distribution of the	31
squamous cell carcinoma	31
described in the	31
between these two	31
t h a	31
a and il	31
infection can be	31
participate in the	31
also in the	31
may be accompanied	31
protein in the	31
sod g a	31
early stages of	31
to contribute to	31
role for the	31
is an essential	31
in vitro assays	31
may be useful	31
there may be	31
are consistent with	31
results indicated that	30
the total number	30
spinal cord of	30
epithelial cells and	30
side of the	30
mice immunized via	30
duration of the	30
have studied the	30
that had been	30
rift valley fever	30
a review of	30
both in vitro	30
h a t	30
acute phase of	30
a loss of	30
by direct contact	30
and of the	30
was to determine	30
response to infection	30
in agreement with	30
institute of technology	30
of mg kg	30
to be expressed	30
relative to the	30
mutation in the	30
is well known	30
by measuring the	30
here we investigated	30
high concentrations of	30
because of its	30
form of the	30
in the respiratory	30
and is a	30
patients suffering from	30
the method of	30
of cells with	30
identified as a	30
the causative agent	30
dendritic cells and	30
administration of a	30
not been reported	30
of both the	30
considered as a	30
be an important	30
in septic patients	30
of the a	30
a phase i	30
importance of the	30
but also the	30
of the intestine	30
resulted in an	30
in more detail	30
play a critical	30
in the body	30
p x r	30
in the dorsal	30
are likely to	30
in the urine	30
by inhibition of	30
the most commonly	30
over the past	30
of the complement	30
also been shown	30
might contribute to	30
belongs to the	30
in clinical trials	30
in the course	30
functional role of	30
been used as	30
our data indicate	30
as described previously	30
these results are	30
is sufficient to	30
inflammation of the	30
and western blot	30
identified in the	30
a part of	30
the mouse is	30
that has been	30
identification of the	30
t cells with	30
we have examined	30
inbred mouse strains	30
could show that	30
in a time	30
for the production	30
these cells are	30
and should be	30
a monoclonal antibody	30
measured by elisa	30
absence of the	30
of septic shock	30
foxn nu mice	30
to an increase	30
not due to	30
t cells by	30
male reproductive tract	30
decreased in the	30
long pentraxin ptx	30
weeks after the	30
is a critical	30
of laboratory rodents	30
were significantly higher	30
in mouse and	30
a change in	30
the response of	29
in cynomolgus macaques	29
fetal bovine serum	29
account for the	29
aspects of the	29
modified vaccinia virus	29
result in a	29
areas of the	29
of nitric oxide	29
after the first	29
is used to	29
stage hli model	29
an in vivo	29
for the identification	29
be seen in	29
not able to	29
than that in	29
levels were measured	29
spleen cells from	29
we established a	29
of the non	29
in the upper	29
the dentate gyrus	29
an inflammatory response	29
closely related to	29
large amounts of	29
of mouse models	29
the phosphorylation of	29
of the salivary	29
in the intestinal	29
the early phase	29
of microglia in	29
early phase of	29
these findings indicate	29
morphologic features of	29
immune response against	29
was dependent on	29
neurons of the	29
class i and	29
with h n	29
the phenotype of	29
innate immune system	29
the emergence of	29
in an in	29
blood glucose levels	29
host immune response	29
and at the	29
host response to	29
transgenic mice with	29
in the circulation	29
the objective of	29
in the distal	29
the muscularis mucosa	29
prkdc scid mice	29
in infant mice	29
we will discuss	29
and the development	29
the introduction of	29
to the human	29
mechanisms underlying the	29
in a rat	29
in man and	29
give rise to	29
application of the	29
serves as a	29
we examined whether	29
were identified in	29
were performed on	29
vaccinia virus ankara	29
the assessment of	29
is a complex	29
in human and	29
following administration of	29
of the viral	29
the virus was	29
i n g	29
important role of	29
the cell membrane	29
are required to	29
up to of	29
the expression level	29
only a few	29
and the number	29
in bone marrow	29
of the primary	29
mice and in	29
area of the	29
the guinea pig	29
must be differentiated	29
to wild type	29
may be seen	29
this type of	29
are listed in	29
aim of our	29
we report the	29
but not of	29
the intestinal tract	29
by western blotting	29
and do not	29
by in situ	29
by use of	29
has been studied	28
proliferation of the	28
were identified by	28
the understanding of	28
their capacity to	28
regulated by the	28
basement membrane integrity	28
to be highly	28
proven to be	28
of b cell	28
the change in	28
as a marker	28
activated t cells	28
gaba a receptors	28
cellular immune responses	28
in the s	28
role of this	28
this model is	28
to be of	28
significantly higher than	28
was blocked by	28
as one of	28
c f mice	28
acute and chronic	28
induced in the	28
increased risk of	28
the large intestine	28
basis of the	28
nucleus of the	28
involvement of the	28
as an important	28
disease in humans	28
assessment of the	28
such as il	28
the clearance of	28
to be determined	28
respect to the	28
the first days	28
rat model of	28
do not have	28
are composed of	28
influenced by the	28
well as to	28
sohn and couto	28
focused on the	28
the protective effect	28
for in vitro	28
in the wild	28
of the main	28
to control the	28
in normal mice	28
together with the	28
the molecular basis	28
that there are	28
in the group	28
of transgenic mice	28
ability of the	28
in a single	28
in presence of	28
the uptake of	28
virus replication in	28
it is therefore	28
the h r	28
been detected in	28
mesenchymal stem cells	28
not lead to	28
a significant role	28
oral administration of	28
infection with a	28
molecular mechanisms underlying	28
part of a	28
plays a crucial	28
view of the	28
the discovery of	28
relationship between the	28
virus in mice	28
in the host	28
mice inoculated with	28
of body weight	28
allowed us to	28
and secretion of	28
the complement system	28
were cultured in	28
be important in	28
the area of	28
response of the	28
vd t cells	28
the functions of	28
effects in the	28
the sensitivity of	28
better understand the	28
japan we have	28
transient receptor potential	28
was added to	28
inhibitory effect of	28
of type diabetes	28
is also a	28
of the effects	28
studies of the	28
of the b	28
experimental autoimmune encephalomyelitis	28
whether or not	28
inflammatory cell infiltrate	28
are mediated by	28
to bind to	28
be expressed in	28
is capable of	28
mice than in	28
i t h	28
via the tc	28
hematopoietic stem cell	28
in gene expression	28
increased numbers of	28
cells in a	28
or in the	28
might be involved	28
department of anatomy	28
mice were sacrificed	28
the c bl	28
the differences in	28
and flow cytometry	28
th and th	28
are important in	27
and duration of	27
of dengue virus	27
the molecular mechanism	27
contributing to the	27
mice showed a	27
peripheral blood of	27
in hek cells	27
in the mammalian	27
inhibitory effects of	27
to play an	27
proved to be	27
has been associated	27
at the cell	27
in the inflammatory	27
structure and function	27
infection and disease	27
riken brain science	27
it is unclear	27
is followed by	27
were immunized with	27
as demonstrated by	27
there are two	27
be observed in	27
been demonstrated to	27
in of the	27
of tumor cells	27
influence of the	27
adjacent to the	27
factor in the	27
cells at the	27
in scid mice	27
affected by the	27
it was suggested	27
a component of	27
that they are	27
system in the	27
production of the	27
spinal cord and	27
signaling in the	27
studies in mice	27
the tca cycle	27
and mg kg	27
which leads to	27
the disease is	27
shown in figure	27
incorrect nose pokes	27
animal models are	27
mice were used	27
in aged mice	27
susceptible to infection	27
in vivo in	27
with the use	27
is expressed by	27
old tg mice	27
of monoclonal antibodies	27
oxidative stress in	27
cd cd cells	27
cells but not	27
have been studied	27
humanized blt mice	27
in the oral	27
t cell lines	27
determination of the	27
at the site	27
were injected with	27
be the most	27
from to days	27
and did not	27
in rats treated	27
of class i	27
the effectiveness of	27
in the usa	27
bl mice were	27
of more than	27
cytotoxic t cells	27
of epithelial cells	27
analyses were performed	27
we have been	27
mainly in the	27
significantly increased the	27
the availability of	27
national institute for	27
the source of	27
in this work	27
t cells that	27
a lesser extent	27
the most potent	27
activated protein kinase	27
of the family	27
was also found	27
in vitro with	27
laboratory mice and	27
in a concentration	27
into the brain	27
the mice immunized	27
after incubation with	27
decrease of the	27
we previously reported	27
cell proliferation in	27
t r a	27
not significantly different	27
they do not	27
to the pathogenesis	27
the ca region	27
receptor for the	27
japan in the	27
the results showed	27
was obtained from	27
in the bla	27
the substantia nigra	27
the quality of	27
of this work	27
be attributed to	27
patients with sepsis	27
in the following	27
of the liver	27
bone marrow cells	27
mice per group	26
the expression levels	26
as seen in	26
were also observed	26
the dynamics of	26
this is a	26
and nk cells	26
remain to be	26
beneficial effects of	26
it is likely	26
the morphology of	26
no evidence of	26
the base of	26
were higher in	26
the gene expression	26
a single dose	26
by administration of	26
g a mice	26
the cd cd	26
treatment of the	26
were divided into	26
been studied in	26
experimentally infected with	26
measured in the	26
t cells to	26
of cd cd	26
of inflammation and	26
most of these	26
are exposed to	26
interaction with the	26
the characteristics of	26
pathogenesis of the	26
provide evidence that	26
virus infection of	26
the lung and	26
the mouse genome	26
role of these	26
is required to	26
mechanism for the	26
of amino acids	26
production in the	26
in endothelial cells	26
of the gastrointestinal	26
of a new	26
of mhc class	26
functions as a	26
wt and vim	26
attached to the	26
were increased in	26
high degree of	26
in the gastrointestinal	26
islets of langerhans	26
dependent protein kinase	26
may occur in	26
by activation of	26
the basis for	26
variation in the	26
the underlying mechanisms	26
hepatitis c virus	26
in the anterior	26
b and c	26
function in the	26
different cell types	26
function as a	26
microglia in the	26
were identified as	26
in spite of	26
on the presence	26
minute virus of	26
layers of the	26
salivary glands of	26
a rat model	26
play a crucial	26
the suppression of	26
human b cells	26
of the olfactory	26
adoptive transfer of	26
and severity of	26
to the cns	26
accordance with the	26
in the murine	26
gene expression and	26
an attempt to	26
and protein expression	26
of mice in	26
the serum levels	26
and mortality in	26
clinical signs are	26
belong to the	26
the results show	26
these results suggested	26
mrna levels of	26
studies have demonstrated	26
in the elderly	26
can be a	26
are poorly understood	26
with a single	26
and use of	26
dengue virus infection	26
model has been	26
studies indicate that	26
mechanisms of the	26
systemic lupus erythematosus	26
may play an	26
production of inflammatory	26
neuronal activity in	26
with those of	25
and production of	25
were prepared from	25
and an increase	25
of innate immunity	25
in a wide	25
of the clinical	25
the etiology of	25
been proposed to	25
hantavirus pulmonary syndrome	25
tumour necrosis factor	25
dose of mg	25
we aim to	25
been used in	25
glial cells in	25
in the tumor	25
changes of the	25
virus infection and	25
and that this	25
the route of	25
course of infection	25
our data demonstrate	25
led to an	25
in mice lacking	25
outside of the	25
in the mucosa	25
of in vivo	25
adverse effects of	25
was due to	25
may serve as	25
as a major	25
of the pro	25
small animal models	25
of the spleen	25
to measure the	25
induction of il	25
in the gastric	25
after infection with	25
to those in	25
is a useful	25
more than one	25
were quantified by	25
high fat diet	25
in the c	25
that observed in	25
was suggested that	25
most commonly used	25
an essential role	25
be important for	25
lower levels of	25
in our laboratory	25
and suggest that	25
mice and the	25
the density of	25
in the intestine	25
not fully understood	25
in the ventral	25
of the control	25
the significance of	25
increased number of	25
was significantly increased	25
were approved by	25
cell responses to	25
in the cortex	25
placed on the	25
sequence of the	25
in the second	25
t cell development	25
to ensure that	25
human t cell	25
be explained by	25
epithelial cells of	25
and does not	25
of tg mice	25
induced activation of	25
new insights into	25
the finding that	25
p ink a	25
the decrease in	25
of the antibody	25
by the addition	25
of the target	25
cells such as	25
the intensity of	25
production of ifn	25
different stages of	25
and in a	25
to quantify the	25
from the brain	25
types of cell	25
have reported that	25
formation of a	25
signs of disease	25
of the th	25
the lungs and	25
evidence that the	25
the inflammatory process	25
binding of the	25
for more than	25
role in regulating	25
mice injected with	25
our data show	25
cells isolated from	25
objective of this	25
the activities of	25
and additional file	25
cells and macrophages	25
test this hypothesis	25
of cell surface	25
transmission electron microscopy	25
play a key	25
we have reported	25
positive cells in	25
in the current	25
was significantly lower	25
of neutrophils in	25
in the culture	25
independent of the	25
corresponding to the	25
to the lung	25
significant role in	25
have been implicated	25
of virus in	25
to mouse hepatitis	25
critically ill patients	25
in these models	25
measured by the	25
protein expression in	25
the upper respiratory	25
the actin cytoskeleton	25
been isolated from	25
a population of	25
molecular basis of	25
not only in	25
of inflammatory mediators	25
of these mice	25
was detected by	25
of cytokines and	25
knowledge of the	25
this has been	25
to prevent the	25
significant differences between	25
the transfer of	25
of glial cells	25
of the genus	25
results of the	25
of the antigen	25
were studied in	25
neutrophils in the	25
has the potential	25
viral replication in	25
murine models of	25
significantly lower in	24
the determination of	24
respiratory tract of	24
were determined in	24
infected mice were	24
tested for their	24
with an increased	24
thermo fisher scientific	24
play a major	24
showed an increase	24
is independent of	24
by the administration	24
localization of the	24
p x receptor	24
length of the	24
in wt mice	24
a t i	24
by cd t	24
may be responsible	24
in the striatum	24
of laboratory animal	24
gaba a receptor	24
the long pentraxin	24
by an increase	24
peripheral nervous system	24
cause of death	24
was present in	24
highly susceptible to	24
of the laboratory	24
is known as	24
accompanied by an	24
in the hypothalamus	24
be achieved by	24
suppression of the	24
during the acute	24
the h n	24
in astrocytes and	24