Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-255697-trig04hdHow long do nosocomial pathogens persist on inanimate surfaces?
cord-002282-ldfa616aToward the global elimination of hepatitis B virus transmission Optimization of elastin- like polypeptide fusions for expression and purification of recombinant proteins in plants Plant- based edible vaccine against HBV Oral immunization of human with transgenic lettuce expressing hepatitis B surface antigen The twenty- year story of a plant- based vaccine against Hepatitis B: Stagnation or promising prospects?
cord-017948-fqhl1qb4Emerging infectious disease agents and their potential threat to transfusion safety Detection of prion infection in variant Creutzfeldt- Jakob disease: a blood- based assay Threat of dengue to blood safety in dengue- endemic countries PCR detection of nearly any dengue virus strain using a highly sensitive primer cocktail Do babesiosis and malaria share a common disease process?
cord-004605-gsi4yxzjHow contagious is vaccinia?
cord-026112-58sa5z03Antiretroviral drug resistance mutations in naïve Islamic Republic of Iran AIDS Progress Report HIV-1 genetic diversity and transmitted drug resistance frequency among Iranian treatment- naive, sexually infected individuals Epidemiological distribution and genotype characterization of the hepatitis C virus among HIV patients in Kashan High prevalence of HCV coinfection in HIV- infected individuals in Shiraz, Islamic Republic of Iran Sexually transmitted hepatitis C infection: the new epidemic in MSM?
cord-297077-p604vvbiThe role of epidemic infectious diseases in the discovery of America Germs of disaster: the impact of epidemics on Japanese military campaigns in Taiwan, 1874 and 1895 Evolution and dispersal of the genus Homo: a landscape approach Vectors vs. humans in Australia-- who is on top down under?
cord-006856-b1w25ob5P21 FTY720 interferes with effector functions and downregulates protein expression of S1P1 and S1P4 in human dendritic cells tures with FTY720/ FTY720-P- treated DC illustrated a cytokine production profile with a lower IFN-?( 22% vs. 25% relative reduction) and a higher IL-4( 64% vs. 92% relative increase), indicating a shift from Th1 toward Th2 differentiation as previously evinced for S1P. DC yields, phenotypic differentiation into iDC and mDC( besides a minor reduction in CD18 surface expression), as well as the investigated mechanisms of iDC antigen uptake( bacterial phagocytosis, mannose receptor- mediated, and fluid- phase endocytosis), were not affected at therapeutically relevant concentrations.
cord-275104-imqmyqhzIs CD8 T cell fate determined by the environment?
cord-293646-d4qcckh1The bicyclic lactam 22 is a mechanismbased inhibitor of HCV NS3 whilst additional examples of bis- benzimidazole derivatives that rely upon Zr?'
cord-015941-4fz79wzfComparison of a commercial IgM capture ELISA with dengue antigen focus reduction microneutralization test and the centers for disease control dengue IgM capture- ELISA PCR detection of nearly any dengue virus strain using a highly sensitive primer cocktail Do babesiosis and malaria share a common disease process?
cord-286719-1xjmlwqrCytomegalovirus: pathogen, paradigm, and puzzle International consensus guidelines on the management of cytomegalovirus in solid organ transplantation Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns Is HCMV a tumor promoter?
cord-325280-4whzcmqvwhat's the future holding for us?
cord-331731-c2r0kfazkey: cord-331731-c2r0kfaz authors: Anugwom, Chimaobi M; Aby, Elizabeth S; Debes, Jose D title: Inverse association between chronic hepatitis B infection and COVID-19: immune- exhaustion or coincidence?
cord-350964-0jtfc271How Important Are Rats As Vectors of Leptospirosis in the Mekong Delta of Vietnam?
cord-312965-5hcb15xcAntiviral treatment for chronic hepatitis B virus infection- immune modulation or viral suppression?
cord-320106-thre6r63Therefore, we classified three BCP/ PC mutation statuses as BCP-/PC-, BCP?/PCand BCP±/PC?
cord-002687-ql6zo8ka: what should be the goal for new therapies?
cord-002687-ql6zo8kaNovel mechanism of antibodies to hepatitis B virus in blocking viral particle release from cells Processing of X- ray diffraction data collected in oscillation mode Crosstalk between human IgG isotypes and murine effector cells Antiviral monoclonal antibodies: can they be more than simple neutralizing agents?
cord-005953-5z89yeb6Aortenklappenstenose auf den klinischen Langzeitverlauf nach Aortenklappenersatzoperation?
cord-005953-5z89yeb6Nichtinvasive Bestimmung des Herzzeitvolumens mittels Inertgas- Rückatmung und CW- Doppler- Ultraschall-Sind die Ergebnisse vergleichbar?
cord-324984-ojrpsdt9, in patients infected with HIV-1 Chemokine control of West Nile virus infection Virological and immunological response to antiretroviral regimens containing maraviroc in HIV type 1-infected patients in clinical practice: role of different tropism testing results and of concomitant treatments Intensification of a raltegravir- based regimen with maraviroc in early HIV-1 infection Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates( S)-methyl-1-piperazinyl]-4-methylpiperidine( Sch-417690/ Sch- D), a potent, highly selective, and orally bioavailable CCR5 antagonist Pharmacokinetics and short- term safety of 873140, a novel CCR5 antagonist, in healthy adult subjects An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-Fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H- imidazo[4, 5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide( PF-232798) Is PF-232798 a possible successor to maraviroc?
cord-324984-ojrpsdt9molecular chaperone inhibitors: are we there yet?
cord-318570-wj7r6953Do You Need a DBS Test?
cord-318570-wj7r6953app- based multiplex, point- of- care screening strategy for HIV and related coinfections affect timely quality antenatal screening of rural Indian women?
cord-274080-884x48onMolecular mechanism of divalentmetal- induced activation of NS3 helicase and insights into Zika virus inhibitor design HCV infection by cell- to- cell transmission: choice or necessity?
cord-274080-884x48onNovel ESCRT functions in cell biology: spiraling out of control?
cord-286334-d9v5xtx7Is there within- season waning of influenza type/ subtype vaccine effectiveness with increasing time since vaccination?
cord-286334-d9v5xtx7What to do next to control the 2019-ncov epidemic?
cord-016704-99v4brjfA changing scene?
cord-016704-99v4brjfHuman normal immunoglobulin( HNIG), 500 mg, deep intramuscular in gluteal muscle should be used in the following circumstances: • Has the detainee traveled to Africa, South East Asia, the Indian subcontinent, Central/ South America, or the Far East in the last 6- 12 months?
cord-016704-99v4brjfThe White Plague: down and out, or up and coming?
cord-030369-4dn02a35If the strict definition of acute and subacute liver failure as"no past history of liver disease"is executed, how to name the patients who had a history of chronic liver disease( caused by HBV from mother to child transmission in China)?
cord-030369-4dn02a35When should"I"consider a new hepatitis B virus genotype?
cord-030369-4dn02a35is tenofovir the answer?
cord-285505-8norumv6: What opportunity exists for a better nucleoside/ nucleotide to treat hepatitis C?
cord-285505-8norumv6In contrast, there was far less protection in clinical trials-why?
cord-285505-8norumv6Is it possible that raltegravir is inducing a single round of HIV replication, to give an increase in HIV circles?
cord-285505-8norumv6What is the role of T- cell responses?
cord-347710-ff64y6ef: where do we stand?
cord-347710-ff64y6efHsp90 inhibitors: a potential treatment for latent EBV infection?
cord-347710-ff64y6efThe hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics The ins and outs of tubulin acetylation: more than just a post- translational modification?
cord-347710-ff64y6efdiagnostic, prognostic, predictive, and treatment implications Altered states: selectively drugging the Hsp90 cancer chaperone Heat shock proteins promote cancer: it's a protection racket Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
cord-275795-ee7qyw5hAlpha- beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection Correlates of protective immunity in poxvirus infection: where does antibody stand?
cord-275795-ee7qyw5hCirculating rotavirus- specific T cells have a poor functional profile Fulfilling the promise of rotavirus vaccines: how far have we come since licensure?
cord-275795-ee7qyw5hIntracellular IFN- gamma expression in natural killer cells precedes lung CD8 þ T cell recruitment during respiratory syncytial virus infection HBV pathogenesis in animal models: recent advances on the role of platelets Basis of rabies virus neurovirulence in mice: expression of major histocompatibility complex class I and class II mRNAs Postlicensure effectiveness of varicella vaccine during an outbreak in a child care center Management of rabies in humans Vaccinia virus vaccines: past, present and future Hepatitis A virus in West Africa: is an epidemiological transition beginning?
cord-275795-ee7qyw5hThe T¼4 envelope of Sindbis virus is organized by interactions with a complementary T¼3 capsid Bystander target cell lysis and cytokine production by dengue virus- specific human CD4(þ) cytotoxic T- lymphocyte clones What is immune privilege( not)?
cord-275795-ee7qyw5hThe global burden of viral hepatitis from Analysis of T cell responses during active varicella- zoster virus reactivation in human ganglia REVIEW PAPER: pathology of animal models of alphavirus encephalitis Interview about immune privilege with Memory CD8 T cells in RSV infection: friend or foe?
cord-344084-z4t2wkgk, the following question arose: does CCR5 have any clinically relevant influence on SARS- CoV-2 or other coronaviruses infections?
cord-344084-z4t2wkgk: forgotten or ignored?
cord-344084-z4t2wkgkAn emerging interplay between extracellular vesicles and cytokines Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d- restricted NKT cells CCR5 in T cell- mediated liver diseases: what's going on?
cord-344084-z4t2wkgkCCR5 polymorphism as a protective factor for hepatocellular carcinoma in hepatitis B virus- infected Iranian patients CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface Effects of the CCR5-Δ32 mutation on antiviral treatment in chronic hepatitis C Effects of the CCR5-Δ32 mutation on hepatitis C virus- specific immune responses in patients with haemophilia CC- chemokine receptor 5( CCR5) in hepatitis C-- at the crossroads of the antiviral immune response?
cord-344084-z4t2wkgkCells Chemokine receptors as important regulators of pathogenesis during arboviral encephalitis Enhanced expression, native purification, and characterization of CCR5, a principal HIV-1 coreceptor Dengue haemorrhagic fever: a job done via exosomes?
cord-027860-s97hdhh6( Do I have cold sores?
cord-027860-s97hdhh6Do I have genital herpes?
cord-027860-s97hdhh6How should this change the way I live my life?).
cord-027860-s97hdhh6The lesions are most Who to Screen?
cord-027860-s97hdhh6The question,"Do you regularly use condoms?"has little relevance to infection control for many sexual practices.
cord-017012-yl0vanuhAcute glomerulonephritis associated with varicella infection Varicella infection in a renal transplant recipient associated with abdominal pain, hepatitis, and glomerulonephritis Nephrotic syndrome associated with varicella infection Epstein- Barr virus- associated acute interstitial nephritis: infection or immunologic phenomenon?
cord-017012-yl0vanuhDifferent pathohistological presentations of acute renal involvement in Hantaan virus infection: report of two cases Clinical characteristics of haemorrhagic fever with renal syndrome in children Prospects for treatment of viral haemorrhagic fever with ribavirin, a broad spectrum antiviral drug Lassa fever: effective therapy with ribavirin Human infection with highly pathogenic H5N1 influenza virus Renal insufficiency on presentation of bird flu infection: is it correlated to outcome?
cord-017012-yl0vanuhDoes antimicrobial therapy of streptococcal pharyngitis or pyoderma alter the risk of glomerulonephritis?
cord-017012-yl0vanuhImpact of antibiotics on expression of virulence?
cord-017012-yl0vanuhPhiladelphia Schistosomal specific nephropathy leading to end- stage renal failure Is glomerulopathy due to schistosomiasis mansoni disappearing?
cord-017012-yl0vanuhthe balance right Comparison of three fluid solutions for resuscitation in dengue shock syndrome Epidemiology and clinical features of Crimean- Congo haemorrhagic fever in Southern Africa Viral hemorrhagic fever- induced acute kidney injury Hantavirus: an increasing problem?
cord-331289-02411gfvA review on its molecular characteristics and role in medicine Hepatitis B virus testing by minipool nucleic acid testing: does it improve blood safety?
cord-331289-02411gfvA single mutation in chikungunya virus affects vector specificity and epidemic potential Parvovirus transmission by blood products-a cause for concern?
cord-331289-02411gfvIs the incidence and prevalence of inhibitors greater with recombinant products?
cord-331289-02411gfvPrevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates Evidence for the continued transmission of parvovirus B19 in patients with bleeding disorders treated with plasma- derived factor concentrates Human parvovirus B19 Viral pathogens Hepatitis E screening for blood donations: an urgent need?
cord-331289-02411gfvUse and interpretation The reliability of HBV core antibody in serological screening for hepatitis B virus World Health Organisation( WHO) Laboratory diagnostics for hepatitis C virus infection Hepatitis C virus core antigen testing: role in diagnosis, disease monitoring and treatment Hepatitis C diagnostics: clinical evaluation of the HCVcore antigen determination Transfusion- transmitted hepatitis E: is screening warranted?
cord-296979-8r851j4tCan the target genes affect virion assembly, or affect replication and spread of the virus through regulating viral transcription to block its transmission?
cord-296979-8r851j4tCan we assume that these host genes together function to maintain homeostasis?
cord-296979-8r851j4tHuman embryonic genome activation( EGA) occurs at the 4- 8 cell stage[ 40, 41], why host genes can regulate HBV gene expression in two- cell embryos?
cord-296979-8r851j4tIt is unknown whether the target genes identified in the current study are included in ESSP4?
cord-296979-8r851j4tOocyte- expressed yes- associated protein is a key activator of the early zygotic genome in mouse Golden hamster embryonic genome activation occurs at the two- cell stage: correlation with major developmental changes X region mutations of hepatitis B virus related to clinical severity Understanding the host genetics of chronic hepatitis B and C, Semin Does severe teratozoospermia affect blastocyst formation, live birth rate, and other clinical outcome parameters in ICSI cycles?
cord-296979-8r851j4tRefining the risk estimate for transfusion- transmission of occult hepatitis B virus Epidemiological and molecular features of hepatitis B and hepatitis delta virus transmission in a remote rural community in central Africa# 38: hepatitis B in pregnancy screening, treatment, and prevention of vertical transmission Hepatitis B transmission by cell and tissue allografts: how safe is safe enough?
cord-296979-8r851j4twhether certain activator( s) deposited in golden hamster oocyte activate human genome?
cord-022607-34hj17sn19 Could APOBEC3 G function by simply binding to C residues in HBV genomic RNA so precluding it from becoming packaged?
cord-022607-34hj17sn20 Finally- looking forward- could the cytokine secretion profiles of intrahepatic T cells be potentially linked to treatment response?
cord-022607-34hj17snBut if so, why should this not occur for HIV replication?
cord-022607-34hj17snCould it be that just beneath the plasma membrane APOBEC3 G acts nonspecifically as a ssDNA cytosine deaminase, whereas deep down in the endoplasmic reticulum where HBcAg particles are assembled, it is part of a multiprotein complex that modulates the activity of the APOBEC3 G subunit?
cord-022607-34hj17snHow can one square HBV restriction by APOBEC3 G when there is little expression of APOBEC3 G in the normal liver?
cord-022607-34hj17snThe questions that emerge then are: Are such T cells fully functional in the intrahepatic environment, and how does such activity relate to disease progression?
cord-022607-34hj17snWhat are these genes, denoted APOBEC3A- G?
cord-022607-34hj17snWhat is the role of intrahepatic virus- specific CD8ϩ T cells in determining acute viral clearance and immunopathology?
cord-022607-34hj17snWhy, then, might some patients generate IL-10-secreting T- cell populations and others not?
cord-032183-yqqqe325An integration of deep viral suppression with sequential immune modulation( cocktail therapy) to restore antiviral capacity: the future of chronic hepatitis B?
cord-032183-yqqqe325Dissecting the divergent effects of interferon- alpha on immune cells: time to rethink combination therapy in chronic hepatitis B?
cord-032183-yqqqe325Does antiviral therapy reduce complications of cirrhosis?
cord-032183-yqqqe325Entecavir treatment prevents disease progression in hepatitis B virus- related acute- on- chronic liver failure: establishment of a novel logistical regression model Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat?
cord-032183-yqqqe325HBV cure- can we pin our hopes on immunotherapy?
cord-032183-yqqqe325What MELD score mandates use of entecavir for ACLF- HBV HBeAg- negative patients?
cord-032183-yqqqe325hepatitis B immunoglobulin necessary in prophylaxis of hepatitis B recurrence after liver transplantation?
cord-032183-yqqqe325the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy Management of the HBV reactivation in isolated HBcAb positive patients affected with Non Hodgkin Lymphoma Hepatitis B virus reactivation associated with anti- neoplastic therapy Thyroid abnormalities in chronic viral hepatitis and their relationship to interferon alfa therapy Can pegylated interferon alpha 2a cause development of thyroid disorders in patients with chronic hepatitis B?
cord-000083-3p81yr4nBetween patients with HOMA- IR positive and negative, however, statistically no significant difference was found in terms of age, sex, etiology, Child- Pugh classification, spleen size, TNF-?,
cord-000083-3p81yr4nDo we all failed in addressing socio- economic issues of cancer- sufferers?
cord-000083-3p81yr4nIL-1?
cord-000083-3p81yr4nIL-1?
cord-000083-3p81yr4nIL-1?
cord-000083-3p81yr4nIL-1?
cord-000083-3p81yr4nIn additon, we aimed to investigate the relation of insulin resistance in liver cirrhosis with such parameters as age, sex, etiology, Child- Pugh classification, spleen size, TNF-?, IL-1?
cord-000083-3p81yr4nIn additon, we aimed to investigate the relation of insulin resistance in liver cirrhosis with such parameters as age, sex, etiology, Child- Pugh classification, spleen size, TNF-?, IL-1?
cord-000083-3p81yr4nIn liver cirrhosis group, glucose, insulin, C- peptid, HOMA- IR, TNF-?
cord-000083-3p81yr4nIn patients with liver cirrhosis, the levels of glucose, insulin, C- peptid, HOMA- IR, TNF-?, IL-2RES, IL-6, CRP and Hs- CRP increase with respect to normal population.
cord-000083-3p81yr4nIn the study, it was also determined that the mechanism of insulin resistance development occurs independent of age, sex, etiology, Child- Pugh classification, spleen size, TNF-?,
cord-000083-3p81yr4nThe two groups were compared with each other in terms of glucose, insulin, C- peptid, HOMA- IR, TNF-?,
cord-000083-3p81yr4nThese two groups, i.e., HOMA- IR positive and HOMA- IR negative, were compared in terms of age, sex, etiology, Child- Pugh classification, spleen size, TNF-?,
cord-305085-bv7udg9k: prospective cohort study from Durban Are HIVinfected women who breastfeed at increased risk of mortality?
cord-305085-bv7udg9kA further report on cancer of the breast Repeated congenital infection with Toxoplasma gondii Is ingestion of milk associated bacteria by premature infants fed raw human milk controlled by routine bacteriologic screening?
cord-305085-bv7udg9kDoes breast feeding increase the child's risk of breast cancer?
cord-305085-bv7udg9kHIV Infection in Newborns French Collaborative Study Group Clinical Virology Postpartum varicella vaccination: Is the vaccine virus excreted in breast milk?
cord-305085-bv7udg9kHow well will they work were they are needed most?
cord-305085-bv7udg9kIng et al 194 investigated the question,"Does the unsuckled breast have an altered risk for cancer?
cord-305085-bv7udg9kIs breast milk collected at home suitable for raw consumption by neonates in Brizilian public neonatal intensive care units?
cord-305085-bv7udg9kMorbidity in children born to women infected with human immunodeficiency virus in South Africa: Does mode of feeding matter?
cord-305085-bv7udg9kNeonatal group B streptococcal infection related to breast milk Epidemiology of tuberculosis in the United States Probable transmission of brucellosis by breast milk Does discarding the first few milliliters of breast milk improve the bacteriological quality of bank breast milk?
cord-305085-bv7udg9kNew frontiers in an old dilemma Breastfeeding and the risk of life- threatening rotavirus diarrhea: Prevention or postponement?
cord-305085-bv7udg9kRevised guidelines from CDC Detection of TT virus DNA and GB virus type C/ hepatitis G virus RNA in serum and breast milk: Determination of mother- to- child transmission Effects of hepatitis A and B in pregnancy on the mother and fetus Human immunodeficiency virus load in breast milk, mastitis and mother- to- child transmission of human immunodeficiency virus type 1 How contagious is vaccinia?
cord-305085-bv7udg9kThe yeast connection: is Candida linked to breastfeeding associated pain?
cord-305085-bv7udg9kWhich measures for which success?
cord-305085-bv7udg9kWho should receive rifampin?
cord-265472-b1s4stvz5 case reports Cutaneous polyarteritis nodosa in a child following hepatitis B vaccination Systemic polyarteritis nodosa following hepatitis B vaccination Kawasaki disease in an infant following immunisation with hepatitis B vaccine Yellow fever vaccination and Kawasaki disease Churg- strauss vasculitis with brain involvement following hepatitis B vaccination ANCA- associated vasculitis following influenza vaccination: causal association or mere coincidence?
cord-265472-b1s4stvz: does it induce autoimmunity and cutaneous sclerosis?
cord-265472-b1s4stvzA review on the association between inflammatory myopathies and vaccination Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes Etiology of fibromyalgia: the possible role of infection and vaccination Infection and vaccination in chronic fatigue syndrome: myth or reality?
cord-265472-b1s4stvzBullous pemphigoid after herpes zoster vaccine administration: association or coincidence?
cord-265472-b1s4stvzCan immunisation trigger rheumatoid arthritis?
cord-265472-b1s4stvzDoes influenza vaccination induce bullous pemphigoid?
cord-265472-b1s4stvzThe immunobiology of aluminium adjuvants: how do they really work?
cord-265472-b1s4stvzThe mosaic of autoimmunity Infections and autoimmunity- friends or foes?
cord-265472-b1s4stvzThe pro- oxidant activity of aluminum Regulatory role of zinc during aluminium- induced altered carbohydrate metabolism in rat brain Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?
cord-265472-b1s4stvzVaccine safety datalink team Efficacy and duration of immunity after yellow fever vaccination: systematic review on the need for a booster every 10 years Risk of yellow fever vaccine- associated viscerotropic disease among the elderly: a systematic review Bacillus calmette- guérin immunotherapy for genitourinary cancer Arthritis after BCG vaccine in a healthy woman Dermatomyositis after B.C.G. vaccination Aetiopathogenesis of Takayas's arteritis and BCG vaccination: the missing link?
cord-265472-b1s4stvzanti- TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice Is narcolepsy a classical autoimmune disease?
cord-265472-b1s4stvzautoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss?
cord-265472-b1s4stvzfollowing human papillomavirus vaccination HBV vaccine and dermatomyositis: is there an association?
cord-265472-b1s4stvzinterferon alpha-2b confer additional benefit in the adjuvant treatment of high- risk melanoma?
cord-265472-b1s4stvzvaccination- a case report Human papillomavirus( HPV) vaccine policy and evidence- based medicine: are they at odds?
cord-318853-mxyxwkhx5 5'UTR geq/ ml at 16 weeks be visible immunologically, but envelope proteins derived from EeRNA sequences corresponding to~10 6- 7 5'UTR geq/ ml at 4- 6 weeks remain unseen?
cord-318853-mxyxwkhxAnalysis of cloned DNA gives cleaner data than PCR sequencing but if 100 clones( and multiple HCV quasispecies clones are highly unlikely to be identical) provides definitive sequence, would we process the 101 st to reveal different and, potentially, critical sequence variations?
cord-318853-mxyxwkhxAnd if we did, how would we recognise its importance?
cord-318853-mxyxwkhxAs clear evidence exists for viral disruption of leptin function[ 106] and virus- associated weight gain in humans[ 107] and monkeys[ 108], is it possible the global epidemics of type II diabetes mellitus, insulin resistance, hyperlipidaemia and obesity now prevalent[ 109][ 110][ 111][ 112][ 113][ 114][ 115][ 116], are just that; epidemics fundamentally caused by viruses that co- opt insulin or leptin or other associated receptors for cell access and generate protein quasispecies that disrupt receptor function?
cord-318853-mxyxwkhxBut does this certitude reflect reality, at least for viral RNA quasispecies?
cord-318853-mxyxwkhxBut why should specific EeRNA sequence frequencies-in other words, HCV RNA pol fidelity-increase after week 8, facilitating adaptive immune responses?
cord-318853-mxyxwkhxCould it also be that ethnically based epidemics of obesity, diabetes mellitus, hypertension and reno- vascular disease( the'metabolic syndrome'), as seen in PIMA Indians, Nauruans and Australian Aborigines[ 115] have developed not primarily because of exposure to"Western"foods and lifestyles-that, after all, are all- pervasive without necessarily having so dramatic an effect on other groups-but because of chronic or recurrent exposure to viruses, or genotypes of viruses to which their particular repertoire of receptor polymorphisms confer no protection?
cord-318853-mxyxwkhxFinally, if immune mechanisms are unable to clear RNA viruses like HCV and do not cause the reduced viral replication seen during acute infection, are they any more likely to be effective against other RNA viruses?
cord-318853-mxyxwkhxI receptor signaling system in JC virus T antigen- induced primitive neuroectodermal tumors-medulloblastomas Hepatitis C virus down- regulates insulin receptor substrates 1 and 2 through up- regulation of suppressor of cytokine signaling 3 Vaccinia virus and the EGF receptor: a portal for infectivity?
cord-318853-mxyxwkhxIs important sequence likely to be present at frequencies of http://www.virologyj.com/content/2/1/70< 1%?
cord-318853-mxyxwkhxIs it possible foetal tolerance is mediated by regulating the fidelity of foetal DNA dependent RNA transcriptases to ensure any cell- surface antigens are expressed heterogeneously and at levels below the threshold of maternal immune responsiveness?
cord-318853-mxyxwkhxIs it possible that self- limiting infections like influenza and SARS also autoregulate their replication, and, like HCV or HBV, become partially dormant, yet remain transcriptionally active, in the face of an active and powerful immune response?
cord-318853-mxyxwkhxThe expected consequences disruption of receptor function by variant viral proteins might explain many common biochemical pathologies; For example, what effect would chronic blockade of parathyroid( PTH) receptors by viral proteins have on PTH levels, the parathyroid glands, or bone?
cord-318853-mxyxwkhxThis is certainly an accurate synthesis of an extensive and highly complex literature but does it make any sense?
cord-318853-mxyxwkhxWhat practical meaning does"immune control"have for the individual?
cord-318853-mxyxwkhxWhy should HCV replicating at 10 6- 7 geq/ ml at week 6 be invisible to the immune system but visible when replicating at 10 5 geq/ ml long term?
cord-010088-s9tfvtao3C- S14- 01 DO WE REALLY NEED FFP?
cord-010088-s9tfvtaoBut is this a myth?
cord-010088-s9tfvtaoBut was the three- gene theory really wrong, when the boundaries of genes were not understood at the time?
cord-010088-s9tfvtaoBut who decides what is false?
cord-010088-s9tfvtaoHow can they be investigated and what should be considered?
cord-010088-s9tfvtaoHow do I know if I have enough information to write a paper?
cord-010088-s9tfvtaoHow has this happened?
cord-010088-s9tfvtaoHow should my paper be put together to give it the best chance of being accepted?
cord-010088-s9tfvtaoIf it is returned to me with comments from the reviewers, what should I do?
cord-010088-s9tfvtaoIs it an ATMP or non- manipulated cell product, is it a blood product or a pharmaceutical?
cord-010088-s9tfvtaoNEXT?
cord-010088-s9tfvtaoWHATS NEW WITH TRALI?
cord-010088-s9tfvtaoWhat happens to my paper after I submit it?
cord-010088-s9tfvtaoWhat is my next step if my paper is rejected, either without review or with review?
cord-010088-s9tfvtaoWhat is the value of discussing case studies?
cord-010088-s9tfvtaoWhat should be considered in different clinical situations?
cord-010088-s9tfvtaoWhere should I try to publish the paper?
cord-010119-t1x9gkndAmong all potential causes investigated, only the gel card lot number was associated with the number of"?"generated( table 1).
cord-010119-t1x9gkndAssuming 30 seconds of technologist time per"?", we estimate that 13.6 hours were needed to resolve and update these results.
cord-010119-t1x9gkndCan Texting Decrease Wastage?
cord-010119-t1x9gkndInterference: More Than Just Kell?
cord-010119-t1x9gkndIs Its Use Inappropriate?
cord-010119-t1x9gkndOf 19,647 columns run as part of antibody screens, 1,633( 8.3%) columns generated"?
cord-010119-t1x9gkndPatient 1 was a 29 yo female, C2E2c1e1, whose RBCs reacted 11 by ECHO and 31 by NEO with anti- D4, and'?'
cord-010119-t1x9gkndPlatelet Rich Plasma and Quality Control: Is There a Role for the Blood Bank?
cord-010119-t1x9gkndShortly after implementation, technologists reported increased time spent performing manual resolution of indeterminate( designated as"?") results.
cord-010119-t1x9gkndStudy Design/ Method: We analyzed allogeneic interview responses to the screening question,"In the past 12 months have you had a tattoo?"
cord-010119-t1x9gkndStudy Design/ Methods: With assistance from Ortho Diagnostics, analyzer archives were queried to identify the number of gel card columns used for screens, the number of columns with"?"results, and the gel card lot numbers used for testing from 1/29/2017 to 3/31/2017.
cord-010119-t1x9gkndTesting Worth the Headache?
cord-010119-t1x9gkndTexas Children's Hospital, 2 Baylor College of Medicine AP127 Vision Titers--Easier or Problematic?
cord-010119-t1x9gkndThe Future of Plasma Therapy?
cord-010119-t1x9gkndThe incidence of"?"and visually negative analyzer positive results is dependent on the specific lot of MTS- Gel TM cards used.
cord-010119-t1x9gkndThe objective of this study was to investigate the cause of"?"and apparent false positive results on VisionV R three- cell antibody screens.
cord-010119-t1x9gkndVariations in Biochemical Markers of Bone Metabolism during Plateletpheresis: Impact of Socio- Demographic and Lifestyle Factors?
cord-010119-t1x9gkndWere Patients Transfused after Testing?
cord-010119-t1x9gkndWhat Is the Best Practice for Testing Residual White Blood Cells in Blood Components for Monthly Routine Quality Control?
cord-010119-t1x9gkndWhere We Go?
cord-010092-uftc8inxCan you confirm my genotype? cord-010092-uftc8inx Who is a blood donor recruiter?"was the topic of ABD- VII at 9- 11 March 2018.
cord-010092-uftc8inx4A- S18- 05 WHO IS SYPHILIS TESTING EXCLUDING?
cord-010092-uftc8inx: IS IT TIME TO LABEL EACH UNIT WITH HB CONTENT?
cord-010092-uftc8inxA donor was classified as"tired"if they responded"all the time"or"most of the time"to the question"how often do you feel that you lacked energy and strength?".
cord-010092-uftc8inxALL TOGETHER?
cord-010092-uftc8inxAre we alone in the Universe?
cord-010092-uftc8inxAs a consequence, questions asked 30 years ago have changed: Today, molecular biologists looking at hundreds of newly discovered blood group alleles find themselves not being asked by serologists any more:"Can you confirm my serology?", but instead, pose their question to the experts for the blood group phenotype:
cord-010092-uftc8inxBut can we apply the metaphor as successfully into donating blood for research?
cord-010092-uftc8inxDonors and Donation-Donor Adherence-are we doing the Right Thing?
cord-010092-uftc8inxHow can we start using this tool in unison with our existing tools to improve science and clinical practice in our respective( bio)medical fields?
cord-010092-uftc8inxSo is there a future for new anti- platelet agents?
cord-010092-uftc8inxTo evaluate self- rated health we used the well- validated single question:"How would you rate your health in general?".
cord-010092-uftc8inxWHAT CAN WE LEARN FROM HOW ADVERSE EVENTS ARE DETECTED?
cord-010092-uftc8inxWhat is the optimal balance between iron supplementation and prolongation of interdonation intervals?
cord-010092-uftc8inxWhat then is the best approach to use?
cord-010092-uftc8inxWhere are we from?
cord-010092-uftc8inxWhere are we going?
cord-010092-uftc8inxWill serologic typing be replaced by DNAbased typing?
cord-010092-uftc8inxbut how does this affect health?
cord-023346-8sqbqjm1( with a selfadministered questionnaire with an open- ended question: How does blood donation affect you?
cord-023346-8sqbqjm1/socially during or after blood donation?) revealed that perceived negative effects( fatigue, diminished physical working capacity, vertigo/ dizziness, susceptibility to infections etc)
cord-023346-8sqbqjm1: will it become reality?
cord-023346-8sqbqjm1After the first 10 years with haemovigilance in the European countries, what has been the outcome of this big effort?
cord-023346-8sqbqjm1Against this background where should our attentions focus?
cord-023346-8sqbqjm1Aim: Does the interpretation of reports obtained through Outcome Review lead to an increase in the number of products per run and the overall productivity of the apheresis center?
cord-023346-8sqbqjm1An ISO standard for blood transfusion?
cord-023346-8sqbqjm1Are transfusion guidelines evidence- based?
cord-023346-8sqbqjm1Being anti- D immunoglobulin a product that has the potential risk of infection transmission, is it appropriate to use indiscriminately as a routine antenatal prophylaxis?
cord-023346-8sqbqjm1In addition, how much are we willing to pay for protection against emerging viruses?
cord-023346-8sqbqjm1Is it a mutual decision making between physician and patient?
cord-023346-8sqbqjm1Mobilization is also seen following the use of other cytokines( i.e. kit- L, Flt-3 L, IL-3) or chemokines( i.e. IL-8, Gro?), complement activation, etc., but the detailed mechanisms or the interdependence of these other pathways with the ones already proposed have not been worked out.
cord-023346-8sqbqjm1Scientific evidence to fully answer the questions'when are platelet components clinically effective'and'what do we really know?'is limited.
cord-023346-8sqbqjm1Should patients with thalassemia intermedia be regularly transfused?
cord-023346-8sqbqjm1The research theme of this questionnaire is as follows:'What is the level of knowledge and of motivation in the non- remunerated and voluntary blood donation at students?'
cord-023346-8sqbqjm1The subjects selected and debated were( i) what are the medical considerations for reducing the rate of mistransfusion?
cord-023346-8sqbqjm1These ties to industry create a tension that actually is or can be perceived as • work internationally; • send young volunteers to international youth forums; • employ young people in your organisation; Why use volunteers in blood donor recruitment?
cord-023346-8sqbqjm1We therefore resorted to developing our own model but ask the question: Why not have one international standard for blood transfusion?
cord-023346-8sqbqjm1What is however the meaning of informed consent?
cord-023346-8sqbqjm1Who cares about the quality of life of the chronic patients treated with blood products?
cord-023346-8sqbqjm1Who will hear it?
cord-023346-8sqbqjm1and( ii) what are the medical considerations for managing a limited blood inventory?
cord-023346-8sqbqjm1to apply which screening method?
cord-023346-8sqbqjm1your Trima ® can be?
cord-023364-ut56gczm( with a selfadministered questionnaire with an open- ended question: How does blood donation affect you?
cord-023364-ut56gczm/socially during or after blood donation?) revealed that perceived negative effects( fatigue, diminished physical working capacity, vertigo/ dizziness, susceptibility to infections etc)
cord-023364-ut56gczm: will it become reality?
cord-023364-ut56gczmAfter the first 10 years with haemovigilance in the European countries, what has been the outcome of this big effort?
cord-023364-ut56gczmAgainst this background where should our attentions focus?
cord-023364-ut56gczmAim: Does the interpretation of reports obtained through Outcome Review lead to an increase in the number of products per run and the overall productivity of the apheresis center?
cord-023364-ut56gczmAn ISO standard for blood transfusion?
cord-023364-ut56gczmAre transfusion guidelines evidence- based?
cord-023364-ut56gczmBeing anti- D immunoglobulin a product that has the potential risk of infection transmission, is it appropriate to use indiscriminately as a routine antenatal prophylaxis?
cord-023364-ut56gczmIn addition, how much are we willing to pay for protection against emerging viruses?
cord-023364-ut56gczmIs it a mutual decision making between physician and patient?
cord-023364-ut56gczmMobilization is also seen following the use of other cytokines( i.e. kit- L, Flt-3 L, IL-3) or chemokines( i.e. IL-8, Gro?), complement activation, etc., but the detailed mechanisms or the interdependence of these other pathways with the ones already proposed have not been worked out.
cord-023364-ut56gczmScientific evidence to fully answer the questions'when are platelet components clinically effective'and'what do we really know?'is limited.
cord-023364-ut56gczmShould patients with thalassemia intermedia be regularly transfused?
cord-023364-ut56gczmThe research theme of this questionnaire is as follows:'What is the level of knowledge and of motivation in the non- remunerated and voluntary blood donation at students?'
cord-023364-ut56gczmThe subjects selected and debated were( i) what are the medical considerations for reducing the rate of mistransfusion?
cord-023364-ut56gczmThese ties to industry create a tension that actually is or can be perceived as • work internationally; • send young volunteers to international youth forums; • employ young people in your organisation; Why use volunteers in blood donor recruitment?
cord-023364-ut56gczmWe therefore resorted to developing our own model but ask the question: Why not have one international standard for blood transfusion?
cord-023364-ut56gczmWhat is however the meaning of informed consent?
cord-023364-ut56gczmWho cares about the quality of life of the chronic patients treated with blood products?
cord-023364-ut56gczmWho will hear it?
cord-023364-ut56gczmand( ii) what are the medical considerations for managing a limited blood inventory?
cord-023364-ut56gczmto apply which screening method?
cord-023364-ut56gczmyour Trima ® can be?
cord-023354-f2ciho6o( with a selfadministered questionnaire with an open- ended question: How does blood donation affect you?
cord-023354-f2ciho6o/socially during or after blood donation?) revealed that perceived negative effects( fatigue, diminished physical working capacity, vertigo/ dizziness, susceptibility to infections etc)
cord-023354-f2ciho6o: will it become reality?
cord-023354-f2ciho6oAfter the first 10 years with haemovigilance in the European countries, what has been the outcome of this big effort?
cord-023354-f2ciho6oAgainst this background where should our attentions focus?
cord-023354-f2ciho6oAim: Does the interpretation of reports obtained through Outcome Review lead to an increase in the number of products per run and the overall productivity of the apheresis center?
cord-023354-f2ciho6oAn ISO standard for blood transfusion?
cord-023354-f2ciho6oAre transfusion guidelines evidence- based?
cord-023354-f2ciho6oBeing anti- D immunoglobulin a product that has the potential risk of infection transmission, is it appropriate to use indiscriminately as a routine antenatal prophylaxis?
cord-023354-f2ciho6oIn addition, how much are we willing to pay for protection against emerging viruses?
cord-023354-f2ciho6oIs it a mutual decision making between physician and patient?
cord-023354-f2ciho6oMobilization is also seen following the use of other cytokines( i.e. kit- L, Flt-3 L, IL-3) or chemokines( i.e. IL-8, Gro?), complement activation, etc., but the detailed mechanisms or the interdependence of these other pathways with the ones already proposed have not been worked out.
cord-023354-f2ciho6oScientific evidence to fully answer the questions'when are platelet components clinically effective'and'what do we really know?'is limited.
cord-023354-f2ciho6oShould patients with thalassemia intermedia be regularly transfused?
cord-023354-f2ciho6oThe research theme of this questionnaire is as follows:'What is the level of knowledge and of motivation in the non- remunerated and voluntary blood donation at students?'
cord-023354-f2ciho6oThe subjects selected and debated were( i) what are the medical considerations for reducing the rate of mistransfusion?
cord-023354-f2ciho6oThese ties to industry create a tension that actually is or can be perceived as • work internationally; • send young volunteers to international youth forums; • employ young people in your organisation; Why use volunteers in blood donor recruitment?
cord-023354-f2ciho6oWe therefore resorted to developing our own model but ask the question: Why not have one international standard for blood transfusion?
cord-023354-f2ciho6oWhat is however the meaning of informed consent?
cord-023354-f2ciho6oWho cares about the quality of life of the chronic patients treated with blood products?
cord-023354-f2ciho6oWho will hear it?
cord-023354-f2ciho6oand( ii) what are the medical considerations for managing a limited blood inventory?
cord-023354-f2ciho6oto apply which screening method?
cord-023354-f2ciho6oyour Trima ® can be?