trigram

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trigram	frequency
the number of	189
to display the	111
who has granted	107
a license to	107
the preprint in	107
is the author	107
granted medrxiv a	107
medrxiv a license	107
license to display	107
has granted medrxiv	107
display the preprint	107
the author funder	107
copyright holder for	103
this version posted	103
holder for this	103
the copyright holder	100
case fatality rate	88
number of cases	83
made available under	79
available under a	79
is made available	79
it is made	79
international license it	76
license it is	76
this preprint this	75
preprint this version	75
preprint in perpetuity	75
for this preprint	75
under a is	66
a is the	66
which was not	58
certified by peer	58
not certified by	58
was not certified	58
by peer review	58
the case fatality	57
of novel coronavirus	53
number of deaths	52
of the epidemic	50
case fatality rates	48
cases and deaths	47
as well as	45
of the outbreak	42
severe acute respiratory	41
case fatality ratio	40
of the covid	39
estimates of the	39
version posted may	38
total number of	37
due to the	37
in order to	36
of the disease	36
in this study	36
acute respiratory syndrome	35
in patients with	34
version posted october	34
the united states	33
patients with covid	32
to estimate the	32
based on the	32
of confirmed cases	31
of the cfr	30
of the pandemic	30
for this this	28
this this version	28
for each country	27
of coronavirus disease	27
risk of bias	27
the total number	26
in the united	26
estimation of the	26
the proportion of	25
of the population	25
preprint the copyright	25
number of confirmed	25
the severity of	24
of patients with	24
cumulative number of	24
and case fatality	23
the impact of	23
the crude cfr	23
the risk of	23
the use of	23
h n influenza	23
the end of	22
effective reproduction number	22
a h n	22
distribution of the	22
according to the	22
of the cases	22
clinical characteristics of	22
there is a	22
the time of	21
the probability of	21
cases in the	21
a number of	21
of a pandemic	21
due to covid	21
respiratory syndrome coronavirus	21
pandemic influenza a	21
bacteremic pneumococcal pneumonia	20
likely to be	20
high risk of	20
in relation to	20
as of april	20
number of tests	20
a systematic review	20
world health organization	20
to assess the	19
basic reproduction number	19
the attack rate	19
of severe acute	19
of the countries	19
losses due to	18
the effective reproduction	18
of cases and	18
the treatment of	18
the effect of	18
of convalescent plasma	18
related to the	18
version posted june	17
of the country	17
the distribution of	17
need to be	17
the growth rate	17
the novel coronavirus	17
the case of	17
number of covid	17
of pandemic influenza	17
related productivity losses	17
productivity losses due	17
the age distribution	17
risk factors for	17
of an outbreak	17
the th of	17
confirmed cases and	17
age distribution of	17
social distancing interventions	17
epidemiological characteristics of	16
the cfr of	16
of influenza a	16
the diamond princess	16
the cumulative number	16
case and death	16
the cfr and	16
in the case	16
differences in the	16
the estimation of	16
the effectiveness of	16
the spread of	16
at the time	16
the cfr for	16
influenza a h	16
part of the	16
the level of	16
the beginning of	15
fatality rate of	15
a range of	15
a total of	15
the absence of	15
the cfr is	15
there is no	15
of the time	15
more likely to	15
in the early	15
the value of	15
the course of	15
of the virus	15
and the uk	15
reduction in the	15
of the number	14
be due to	14
quality of air	14
of public health	14
the pandemic period	14
was used to	14
number of infected	14
systematic review and	14
the general population	14
with convalescent plasma	14
for the cfr	14
data on the	14
the first case	14
as the number	14
as a result	14
diamond princess cruise	14
data from the	14
the majority of	14
is important to	14
ministry of health	14
of cases in	14
most of the	14
the ratio of	14
due to death	14
to supplemental oxygen	13
of the first	13
fatality rate and	13
cases of covid	13
of positive cases	13
in terms of	13
infection fatality rate	13
in the database	13
of this study	13
in addition to	13
for disease control	13
of the case	13
it is important	13
cfr and the	13
for patients with	13
gdp per capita	13
of case fatality	13
to evaluate the	13
be used to	13
the influenza pandemic	13
under a perpetuity	13
defined as the	13
n u s	12
early in the	12
effect of hospitalization	12
u s c	12
patients with severe	12
spread of the	12
p t e	12
the basic reproduction	12
number of people	12
reported cases and	12
to understand the	12
the diagnostic rate	12
are likely to	12
the results of	12
i p t	12
in the absence	12
the range of	12
of new cases	12
at the end	12
c r i	12
estimating the case	12
east respiratory syndrome	12
m a n	12
incidence and mortality	12
s c r	12
the cfr in	12
severity of the	12
is likely to	12
in the population	12
middle east respiratory	12
access to supplemental	12
in the treatment	12
total cost of	12
depends on the	12
it is not	12
that the number	12
such as the	12
community contact reduction	12
r i p	12
a n u	12
control and prevention	11
increase in the	11
growth rate of	11
th of february	11
characteristics of patients	11
taken into account	11
of the data	11
an influenza pandemic	11
in each country	11
avian influenza a	11
d m a	11
we calculated the	11
a c c	11
in the age	11
in the first	11
of the infection	11
a cfr of	11
of social distancing	11
and south korea	11
that there is	11
novel coronavirus pneumonia	11
it is possible	11
the time from	11
treatment of severe	11
e p t	11
an outbreak of	11
during the pandemic	11
duration of the	11
c c e	11
compared to the	11
of the novel	11
a factor of	11
onset of symptoms	11
in the future	11
e d m	11
included in the	11
one of the	11
may not be	11
patients infected with	11
figure shows the	11
the rate of	11
the percentage of	11
pscc and cfr	11
t e d	11
the multistep model	11
by the number	11
into account the	11
take into account	11
c e p	11
the importance of	11
are shown in	10
the population of	10
the total cost	10
intensive care unit	10
due to a	10
clinical features of	10
in different countries	10
the cfr was	10
disease control and	10
beginning of the	10
prevention and control	10
is based on	10
by a factor	10
the classic cfr	10
of health and	10
we found that	10
countries in the	10
cfr due to	10
treatment of influenza	10
the outbreak of	10
cases and fatalities	10
and characteristics of	10
at high risk	10
th of march	10
is consistent with	10
associated with the	10
for pandemic influenza	10
depend on the	10
of reported cases	10
the fact that	10
in the usa	10
risk of death	10
of hospitalization on	10
princess cruise ship	10
therapy with a	10
in the range	10
to be the	10
stages of the	10
with a mean	10
the fraction of	10
adult hiv prevalence	10
course of the	10
factors such as	10
can be calculated	9
of cases of	9
in mainland china	9
relation to covid	9
continuous school closure	9
world in data	9
of the growth	9
the duration of	9
of patients dying	9
people in the	9
the confirmed cases	9
a reduction in	9
fraction of observed	9
number of reported	9
an infectious disease	9
review and meta	9
for a pandemic	9
in the following	9
and a standard	9
the mortality rate	9
the association between	9
the growth of	9
and social distancing	9
the delay between	9
growth of the	9
rate of covid	9
size of the	9
the role of	9
there may be	9
the other hand	9
between cfr and	9
in countries with	9
between reported cases	9
confirmed cases of	9
rate and characteristics	9
fatality rates of	9
cfr for covid	9
dying in relation	9
days and a	9
the development of	9
the rasch model	9
which can be	9
fatality ratio for	9
of the manuscript	9
in which the	9
n influenza in	9
to that of	9
a standard deviation	9
for all the	9
large number of	9
of symptoms and	9
on the other	9
account for the	9
to compare the	9
results of this	9
each of the	9
first case of	9
spanish influenza a	9
well as the	9
patients dying in	9
is difficult to	9
convalescent plasma treatment	9
in the pandemic	9
there was a	9
associated with covid	9
of observed cases	9
in south korea	9
reducing the attack	9
of infectious diseases	9
our world in	9
standard deviation of	9
on the cfr	9
of the study	9
of deaths in	9
a pandemic with	9
the world health	9
to have a	9
critically ill patients	8
end of the	8
in hong kong	8
assessment of the	8
transmission of the	8
the analysis of	8
this is the	8
costs are dominated	8
will depend on	8
number of positive	8
and in the	8
transmission dynamics in	8
a mean of	8
the cost of	8
will not be	8
pneumonia in wuhan	8
on the number	8
expected to be	8
be associated with	8
majority of the	8
public health measures	8
the difference between	8
are given in	8
biased due to	8
outbreak of novel	8
the length of	8
rate of the	8
population level morbidities	8
for the covid	8
the possibility that	8
the relationship between	8
the proposed hybrid	8
value of the	8
the italian cfr	8
with the number	8
and public health	8
the countries with	8
shown in table	8
dynamics in wuhan	8
in the country	8
to be a	8
high severity pandemics	8
impact on the	8
in reducing the	8
be explained by	8
pandemic in the	8
this may be	8
data were reported	8
public health interventions	8
analysis of the	8
confirmed cases in	8
the geographic risks	8
cfr of covid	8
of the effective	8
in the cfr	8
mortality associated with	8
it has been	8
of patients infected	8
of tobacco use	8
that the cfr	8
risk of covid	8
is the case	8
that in the	8
the peak of	8
risk factor for	8
older than years	8
is that the	8
characteristics of novel	8
reproduction number of	8
and the number	8
with at least	8
in other countries	8
prevalence of copd	8
the tsd analysis	8
in the outbreak	8
coronavirus disease in	8
understanding of the	8
rates of covid	8
of selection bias	8
time series forecasting	8
the total population	8
prevalence of tobacco	8
novel coronavirus in	8
the presence of	8
low severity pandemics	8
with novel coronavirus	8
social distancing and	8
stage of the	8
were reported in	8
to determine the	8
time delay between	8
taking into account	8
the need for	8
case of covid	8
the dynamics of	8
the same time	8
the period of	8
dynamics of the	8
the definition of	8
phase of the	8
health care systems	8
are dominated by	8
information on the	7
h n virus	7
in the covid	7
of the basic	7
a subset of	7
on the risk	7
mortality and case	7
the differences in	7
for high severity	7
based on a	7
negative correlation with	7
gender differences in	7
the adjusted cfr	7
it would be	7
a statistical analysis	7
social distancing measures	7
compared with the	7
even if the	7
fatality rate for	7
the degree of	7
some of the	7
correlation between cfr	7
number of days	7
of all the	7
assumed to be	7
at the same	7
the simulation model	7
the incidence of	7
probability of death	7
when the number	7
and severity of	7
development of the	7
allowed without permission	7
the h n	7
had the highest	7
to reduce the	7
cfr varied from	7
disease in china	7
estimates for the	7
the real cfr	7
to take into	7
in west africa	7
in the number	7
is an important	7
of a new	7
novel coronavirus diseases	7
of the patients	7
and cfr were	7
it could be	7
is possible that	7
for the treatment	7
at each age	7
were used to	7
the outbreak magnitudes	7
in a population	7
case fatality ratios	7
the delay time	7
the early phase	7
for the country	7
the variance in	7
for the countries	7
found that the	7
lower than the	7
intensive care units	7
early phase of	7
hospitalization on day	7
in our study	7
observed in the	7
conflicts of interest	7
in the current	7
influenza in the	7
patients with pneumococcal	7
of symptom onset	7
changes in the	7
for all countries	7
needs to be	7
was associated with	7
of the current	7
case of the	7
of identified cases	7
personal protective equipment	7
difference between the	7
of the infected	7
similar to that	7
the middle east	7
the lowest total	7
in the post	7
centers for disease	7
number of performed	7
centre for disease	7
number of new	7
of the world	7
no reuse allowed	7
of the variance	7
of the total	7
the st of	7
in real time	7
estimate the number	7
as shown in	7
it is difficult	7
of these patients	7
in the analysis	7
at the beginning	7
is the most	7
in the community	7
of this analysis	7
reuse allowed without	7
used in this	7
use of convalescent	7
antiviral treatment and	7
the time series	7
and the cfr	7
to account for	7
consistent with the	7
public health authorities	7
novel coronavirus infections	7
health care system	7
many of the	7
at least one	7
version posted april	7
the possibility of	7
the epidemiological characteristics	7
fatality rate is	7
characteristics of coronavirus	7
bias in the	7
comparison of the	7
of viral etiology	6
h n pdm	6
there have been	6
national guidelines for	6
number of the	6
used to estimate	6
in conjunction with	6
shown in the	6
the time between	6
the highest cfr	6
relationship between the	6
deaths and the	6
are not included	6
influenza h n	6
in accordance with	6
the severe acute	6
onset to death	6
of cases who	6
case of a	6
between countries and	6
values of the	6
the most effective	6
the time delay	6
transmission and control	6
the public health	6
and quality of	6
the model of	6
followed by a	6
contributed to the	6
is not a	6
presented in table	6
was based on	6
number of fatalities	6
south korea and	6
this is an	6
distribution of times	6
in the same	6
of the proposed	6
a higher cfr	6
the crude cfrs	6
with a cephalosporin	6
for the commencement	6
of bacteremic pneumococcal	6
for low severity	6
pneumoniae urinary antigen	6
cfrs between countries	6
results of the	6
impact of the	6
mortality due to	6
details of the	6
acquired pneumonia in	6
was calculated by	6
we used a	6
fatality rates for	6
this means that	6
number of hospital	6
time series data	6
are consistent with	6
estimates of mortality	6
that there are	6
after adjusting for	6
in the youngest	6
lowest total cost	6
of the same	6
of mortality following	6
to find the	6
is most likely	6
and other epidemiological	6
can be found	6
is associated with	6
absolute reduction in	6
in china and	6
computed using the	6
attack rate to	6
the magnitude of	6
of hospitalized patients	6
coronavirus infections with	6
that can be	6
the availability of	6
the commencement of	6
variation in the	6
estimate the cfr	6
pandemic h n	6
can be used	6
the pandemic in	6
testing and reporting	6
arima model is	6
in the methods	6
outbreak in the	6
of cases is	6
all european countries	6
are presented in	6
proportion of people	6
cases for each	6
in each age	6
during the outbreak	6
the denominator of	6
and the probability	6
the association analysis	6
and a macrolide	6
severe pandemic influenza	6
a result of	6
the reported data	6
analysis of publicly	6
and pandemic influenza	6
and estimates of	6
the risk factors	6
model can be	6
absolute and relative	6
is defined as	6
on the diamond	6
gender difference in	6
number of steps	6
shown to be	6
the onset of	6
patients who were	6
with a lower	6
parameters of the	6
a new disease	6
even in the	6
during an outbreak	6
european centre for	6
the correlation between	6
for disease prevention	6
to be associated	6
that have been	6
of deaths by	6
outbreak in china	6
correlation between the	6
be included in	6
there will be	6
in all european	6
all rights reserved	6
it is likely	6
contribute to the	6
delay between reported	6
with the lowest	6
the history of	6
novel coronavirus disease	6
clinical severity of	6
the numbers of	6
is necessary to	6
relative to the	6
may be more	6
ratio of the	6
patients in the	6
more than of	6
to the time	6
this could be	6
has shown that	6
of the diagnostic	6
to the cfr	6
in the denominator	6
estimate of the	6
for south korea	6
we assume that	6
be able to	6
discussed in the	6
reporting of cases	6
the type of	6
the state of	6
the case for	6
of the national	6
higher than the	6
over years old	6
the epidemic in	6
incidence for the	6
divided by the	6
characteristics of an	6
mathematical modelling of	6
morbidity and mortality	6
of control measures	6
we used the	6
protocol eligibility criteria	6
correlation with cfr	6
distribution with a	6
in this case	6
association analysis between	6
the university of	6
the ndpm model	6
could be used	6
have not been	6
estimate of cfr	6
less likely to	6
of an influenza	6
and sri lanka	6
the arima model	6
close to the	6
ifradj and cdr	6
sources of bias	6
with more than	6
uncertainty in the	6
conservative oxygen strategies	6
department of health	6
dependent on the	6
end of april	6
of infected individuals	6
to have been	6
the imposition of	6
in the world	6
during the first	6
we use the	6
deaths per million	6
of clinical severity	6
evaluation of the	6
ill patients with	6
in the initial	6
characteristics of covid	6
public health emergency	6
to high risk	6
and should be	6
epidemiological and clinical	6
mortality in patients	6
incubation period and	6
been used in	6
of ph n	6
moderate to high	6
the parameters of	6
during the period	6
johns hopkins university	6
days after the	6
for the pandemic	6
high case fatality	6
a future pandemic	6
global burden of	6
fold lower than	6
of hospital beds	6
forecasts of the	6
the cfr ma	6
low and high	6
of health care	6
school closure and	6
on the basis	6
in the literature	6
magnitude of the	6
of infected people	6
of publicly available	6
version posted july	6
depending on the	6
the outbreak in	6
the us cdc	6
the age of	6
for different countries	6
it will be	6
provided by the	6
in the last	6
during the influenza	6
delay between onset	6
and high cases	6
strain of influenza	6
disease prevention and	6
of the spread	6
incubation period of	6
the dataset for	6
causal variables that	6
the incubation period	6
each age group	6
countries with higher	6
it should be	6
south korea on	6
related to covid	6
in the middle	6
the low and	6
per million citizens	6
early transmission dynamics	6
treatment and prophylaxis	6
of pneumococcal pneumonia	6
can be explained	6
between cases and	6
a large number	6
and clinical characteristics	6
seems to be	6
the example of	5
coronavirus pneumonia in	5
online supplementary document	5
high number of	5
during the course	5
number of contacts	5
the data as	5
rate is the	5
a country with	5
the online supplementary	5
the confidence interval	5
broad range of	5
to the public	5
modified logistic model	5
a descriptive study	5
the data from	5
in the end	5
with right truncation	5
of cfr for	5
of the severity	5
in line with	5
probability that a	5
compared to other	5
higher than in	5
the model is	5
the global burden	5
the product of	5
in the two	5
a modelling study	5
of a country	5
on the health	5
treated with convalescent	5
potential biases in	5
severity of an	5
this study was	5
the top states	5
may lead to	5
patients with pneumonia	5
impacts on the	5
it is a	5
at least registered	5
the overall cfr	5
per person for	5
during a surge	5
the current study	5
rate of growth	5
the disease and	5
a public health	5
to examine the	5
denominator of the	5
a lower slope	5
clinical research networks	5
it was not	5
of which are	5
may also be	5
in the other	5
in the s	5
five different countries	5
delay time of	5
of cumulative cases	5
the confidence intervals	5
is greater than	5
for countries with	5
of the situation	5
the health care	5
in estimating absolute	5
use of a	5
by the total	5
may have been	5
the case incidence	5
per country was	5
spread of covid	5
the context of	5
effective in reducing	5
analysis and the	5
we estimate the	5
on cases and	5
and that of	5
measure of the	5
and relative case	5
it is thus	5
on number of	5
from the same	5
in the online	5
associated with a	5
estimating absolute and	5
the ability to	5
that we have	5
kept in the	5
for the ifr	5
distribution of covid	5
we could not	5
in both the	5
have a higher	5
period of the	5
greater than years	5
as the epidemic	5
description of the	5
a wide range	5
real estimates of	5
because they are	5
onset and death	5
hospitalization and death	5
between the cfr	5
number of infections	5
this simulation model	5
values for the	5
evolution of the	5
the reduction in	5
cases in a	5
the tokyo subway	5
taken to be	5
have not yet	5
as to the	5
results in a	5
robust estimation of	5
statistical analysis of	5
the change in	5
and outcomes of	5
it can be	5
data on covid	5
the fatality rate	5
a surge of	5
has become a	5
especially in the	5
the results were	5
and the fraction	5
to the number	5
at moderate to	5
this study are	5
press freedom ranking	5
and reporting of	5
mortality following covid	5
of infected patients	5
and negative correlation	5
first months of	5
attack rate and	5
and approved the	5
cfr for each	5
less than the	5
of tests performed	5
included in this	5
for the usa	5
of the risk	5
peak of the	5
not account for	5
biases in estimating	5
in identified studies	5
deaths due to	5
there was no	5
was followed by	5
shown that the	5
top states that	5
of infected cases	5
as long as	5
schools and universities	5
period and other	5
pandemic influenza mitigation	5
no data were	5
with the highest	5
due to illness	5
of cases reported	5
be found in	5
h n pandemic	5
and deaths were	5
will be a	5
of people aged	5
in the previous	5
the rest of	5
cfr of a	5
of known cases	5
for the next	5
in new zealand	5
outbreak of a	5
and case incidence	5
hospitalized patients with	5
and death counts	5
for each state	5
other epidemiological characteristics	5
in the second	5
and west bengal	5
cfr for the	5
systematic review of	5
productivity losses are	5
that this is	5
a measure of	5
been able to	5
fatality risks during	5
the assumption of	5
delay between the	5
bias on the	5
each country region	5
reason for the	5
is likely that	5
reporting of the	5
that the italian	5
for public health	5
selected saarc countries	5
severe cases and	5
this is a	5
seasonal and pandemic	5
the pandemic is	5
personal fees from	5
viewpoints research theme	5
the variation in	5
shown in figure	5
of the different	5
and number of	5
a set of	5
and had a	5
in the time	5
risks during outbreaks	5
as it is	5
and death data	5
between onset of	5
or asymptomatic cases	5
population of the	5
commencement of oxygen	5
of the model	5
up to the	5
the national institute	5
as in the	5
to mitigate the	5
be regarded as	5
was kept in	5
there are no	5
causal interpretation of	5
of times from	5
which is the	5
to selection bias	5
who have not	5
means that the	5
severity of pandemic	5
the transmission dynamics	5
lower among female	5
of performed tests	5
of reported deaths	5
be related to	5
during the early	5
high cases are	5
of infectious disease	5
acute respiratory infections	5
time series of	5
with bacteremic pneumococcal	5
the size of	5
cumulative case incidence	5
this suggests that	5
data on cases	5
cost of the	5
can be estimated	5
patients who have	5
with pneumococcal pneumonia	5
an example of	5
these findings are	5
tumor necrosis factor	5
dynamics of covid	5
on the th	5
limit analysis to	5
are expected to	5
with influenza a	5
mitigation strategies for	5
the correction factor	5
attack rate by	5
factors associated with	5
the methods section	5
an increase in	5
severity of covid	5
case incidence and	5
the initial outbreak	5
effect on the	5
virus disease in	5
in a small	5
of deaths per	5
adjusted cfr of	5
had been tested	5
ebola virus disease	5
the basis of	5
shifted distribution analysis	5
were more likely	5
reproduction number r	5
to be used	5
for mortality of	5
all the states	5
reported in identified	5
can be seen	5
for treatment of	5
clinical management of	5
days in the	5
for this study	5
it is also	5
for estimating the	5
underlying population level	5
available case data	5
for a range	5
in the present	5
structure of the	5
with respect to	5
and the time	5
as at st	5
affected by the	5
appears to be	5
this is not	5
a novel coronavirus	5
value of cfr	5
for some of	5
the national guidelines	5
number of cumulative	5
the results section	5
they can be	5
that it is	5
patients with cap	5
rate and the	5
severity of coronavirus	5
all infected individuals	5
estimates of cfr	5
severity and fatality	5
the coronavirus disease	5
and community contact	5
and control of	5
in the general	5
of pandemic h	5
the calculated cfr	5
italian cfr was	5
the data was	5
mortality in covid	5
case detection rate	5
by assuming that	5
cfr in patients	5
all of the	5
model of disease	5
with the data	5
the death of	5
applied to the	5
features of patients	5
given that the	5
outbreak start after	5
and more than	5
the infection fatality	5
to differences in	5
adjusting for age	5
allowed us to	5
have shown that	5
of streptococcus pneumoniae	5
and the distribution	5
deaths by the	5
the prevalence of	5
state of the	5
initial stages of	5
population in the	5
infections with right	5
cfr depends on	5
findings suggest that	5
features of the	5
been shown to	5
the addition of	5
a broad range	5
clinical course and	5
if they are	5
a comparison of	5
the selected saarc	5
the remaining countries	5
because of the	5
the study of	5
on google maps	5
risk of mortality	5
publicly available case	5
variance in ndpm	5
occurred in the	5
during a pandemic	5
is expected to	5
with a higher	5
the comparison of	5
age of the	5
bias may be	5
between reporting of	4
pneumonia of unknown	4
publicly available data	4
to the disease	4
cases of novel	4
are summarized in	4
o o f	4
level of respiratory	4
to deal with	4
of a future	4
which could be	4
in a case	4
coronavirus in wuhan	4
institute for health	4
for individual states	4
pandemic severity categories	4
cases and the	4
the pool of	4
the burden of	4
data from a	4
effective potential growth	4
of mainland china	4
time from confirmation	4
we discuss the	4
from the data	4
ratio for a	4
of the patient	4
lower cfr than	4
such as hypertension	4
of critically ill	4
a l p	4
and in other	4
countries with more	4
the cumulative case	4
adjusted case fatality	4
as soon as	4
much higher than	4
we have used	4
public health system	4
the clinical severity	4
deaths caused by	4
read and approved	4
is possible to	4
cases in each	4
and mortality in	4
the ifr for	4
influenza in england	4
in some countries	4
a lot of	4
of the infectious	4
at moderate risk	4
symptoms and the	4
on board the	4
results suggest that	4
global mortality associated	4
the cfr estimates	4
calculation of the	4
early in a	4
of per person	4
board the diamond	4
of avian influenza	4
found to be	4
among female patients	4
novel influenza a	4
the epidemic and	4
this was calculated	4
be taken into	4
showed a significant	4
the reason for	4
publisher full text	4
for the top	4
specific and age	4
in an emergency	4
it difficult to	4
percentage of symptomatic	4
dependence of the	4
the true prevalence	4
see process in	4
of bias assessments	4
could be due	4
difference in cfr	4
has been used	4
the calculation of	4
of school closure	4
at this time	4
the reporting of	4
medrxiv preprint the	4
and medical education	4
in the past	4
number of patients	4
of countries with	4
may be used	4
from the pandemic	4
on patients with	4
have been reported	4
the terminal number	4
we estimated the	4
which is consistent	4
values of r	4
and mortality rate	4
it may be	4
cost of a	4
the estimates of	4
age group and	4
characteristics of cases	4
asymptomatic proportion of	4
incidence of the	4
there has been	4
may be due	4
that they are	4
to the end	4
population of iceland	4
be attributed to	4
the epidemic is	4
and risk factors	4
the result of	4
reported cases of	4
for the age	4
there are a	4
absolute reduction of	4
guidelines for the	4
of icu beds	4
and mortality rates	4
of respiratory protection	4
seemed to be	4
analysis of pandemic	4
countries can be	4
the official data	4
cfr and case	4
the trend of	4
of these factors	4
a single death	4
science and engineering	4
are needed to	4
prevalence has a	4
although highly effective	4
percentage of the	4
deaths and cases	4
the reproduction number	4
this study is	4
by the outbreak	4
to severe acute	4
emerging infectious disease	4
there could be	4
days for the	4
are more likely	4
of symptomatic cases	4
mortality of adult	4
the risk factor	4
higher levels of	4
the authors declare	4
and treatment of	4
used for this	4
center for disease	4
is taken into	4
is plotted on	4
but it is	4
between the observed	4
by at least	4
to public health	4
of an epidemic	4
cfr was observed	4
in the heat	4
years of age	4
excess death data	4
to track covid	4
gamma distribution with	4
note that the	4
to have an	4
with the cfr	4
and target spo	4
the setting of	4
generated by the	4
for the time	4
and death distributions	4
have been published	4
systems science and	4
surge of infections	4
at least two	4
proportion of cases	4
the increase in	4
cfr has been	4
be subject to	4
the true cfr	4
range of countries	4
of follow up	4
pandemics costs are	4
over the age	4
not yet been	4
should be considered	4
inpatients with covid	4
from other countries	4
in the crude	4
that we are	4
the health system	4
person at category	4
the netherlands and	4
countries variance in	4
estimation and application	4
if the data	4
th of april	4
the outbreak on	4
and the high	4
to arrive at	4
convalescent plasma and	4
of the crude	4
in hubei province	4
dominated by productivity	4
feb china jan	4
by using a	4
were excluded from	4
capacity of the	4
subgroup analysis of	4
respiratory syndrome in	4
the gender difference	4
estimate for the	4
rate for covid	4
exactly the same	4
the appearance of	4
infection in a	4
unlikely to be	4
a prospective cohort	4
from the outbreak	4
all authors read	4
a study of	4
the management of	4
model for the	4
dividing the number	4
as a whole	4
characteristics of the	4
an interactive web	4
respiratory syncytial virus	4
before becoming cases	4
to the crude	4
the need to	4
the outbreak and	4
n a l	4
for the disease	4
to calculate the	4
doubling time for	4
in european countries	4
cases reported by	4
process in fig	4
causal effect of	4
variation of the	4
for each of	4
infections is unknown	4
of the real	4
difference in forecasted	4
were significantly lower	4
so that the	4
based on data	4
of the age	4
with a b	4
and the case	4
between case and	4
a delay in	4
fees on covid	4
center for systems	4
are based on	4
of number of	4
early estimates of	4
cause of death	4
sars showed a	4
proportion of coronavirus	4
have suggested that	4
clinical and epidemiological	4
of days and	4
with the disease	4
by age group	4
the cases were	4
some countries have	4
cfr in a	4
shed light on	4
adjusting for the	4
the linear fit	4
and the cumulative	4
the last days	4
as high as	4
italian ministry of	4
could be performed	4
cases by the	4
epidemiology of the	4
in other words	4
is the only	4
pneumococcal pneumonia in	4
and other countries	4
by age and	4
from symptom onset	4
the first cases	4
the strength of	4
magnitudes and cfrs	4
and male patients	4
of the numbers	4
outbreak magnitudes and	4
is due to	4
considered to be	4
hiv prevalence has	4
with the novel	4
of all cases	4
approved the final	4
infection fatality ratio	4
the doubling days	4
cases will be	4
patients who received	4
we propose a	4
individuals who are	4
true number of	4
progress of the	4
a function of	4
wide range of	4
kou et al	4
sudharsanan and colleagues	4
cfr can be	4
of the health	4
of intervention strategies	4
have been identified	4
using a delay	4
for mathematical modelling	4
to predict cfr	4
convalescent plasma for	4
fit the data	4
the many estimates	4
prospective cohort study	4
for which the	4
all the deaths	4
affect the probability	4
of pneumococcal bacteremia	4
with a cfr	4
respiratory distress syndrome	4
all age groups	4
more than a	4
consistent with a	4
the results are	4
to of the	4
insight into the	4
n influenza pandemic	4
to predict the	4
protective equipment for	4
in these countries	4
the data for	4
interval between the	4
the extent of	4
data on test	4
convalescent plasma or	4
to the first	4
accounts for the	4
patients with sars	4
for systematic reviews	4
s pneumoniae urinary	4
emerging influenza pandemic	4
the intensive care	4
end of may	4
pneumonia caused by	4
of the method	4
the initial stages	4
inclusion in the	4
risk assessment of	4
the doubling interval	4
estimating the asymptomatic	4
the curve of	4
infectivity of the	4
between deaths and	4
from the first	4
model of the	4
the true number	4
the transmission risk	4
aged and above	4
to illness and	4
than among male	4
were treated with	4
of the effectiveness	4
convalescent plasma may	4
to use the	4
on the covid	4
patients with sari	4
law enforcement officers	4
patients with influenza	4
in this fashion	4
freedom ranking measure	4
in this paper	4
studies of sars	4
the reporting delay	4
forecasted case incidence	4
proportion of the	4
from further analysis	4
to compute the	4
terminal number of	4
are available for	4
much of the	4
many estimates of	4
the data on	4
would be a	4
specific differences in	4
shows the resulting	4
long as the	4
a case study	4
on confirmed cases	4
data analysis and	4
considered in this	4
within days of	4
use of the	4
ppe may be	4
the first quarter	4
that the real	4
using data from	4
outbreak on the	4
any of these	4
analyses using the	4
to no intervention	4
may also affect	4
of air and	4
cases reported in	4
number of identified	4
the ifr is	4
by the governments	4
medical costs and	4
using a time	4
in the us	4
china and south	4
people aged and	4
tobacco use and	4
the population in	4
in the lower	4
an ongoing epidemic	4
and other factors	4
in the official	4
the early stage	4
of cfr is	4
the cfr with	4
l p r	4
and fatality of	4
health and medical	4
table shows the	4
for the case	4
new york city	4
was used for	4
was identified as	4
in italy was	4
female and male	4
be estimated as	4
ppe must be	4
data provided by	4
potential conflicts of	4
moderate risk of	4
with outbreak start	4
of an emerging	4
compatible with a	4
of cases are	4
had to be	4
incidence of covid	4
this bias may	4
for the general	4
average age of	4
for incidence and	4
serial interval distribution	4
numbers in the	4
time delay is	4
in a single	4
and the latter	4
in the results	4
the selection of	4
of the confidence	4
rate in patients	4
of spread of	4
available at https	4
described in the	4
public health emergencies	4
the asymptomatic proportion	4
estimating the number	4
the heat of	4
of cases for	4
acute respiratory distress	4
the modelled community	4
the accuracy of	4
and as such	4
is similar to	4
analysis in the	4
the residual series	4
of infections and	4
most european countries	4
dashboard to track	4
case incidence for	4
cases per capita	4
enter the dataset	4
multistep model of	4
p r o	4
to adjust the	4
of the sars	4
in which individuals	4
of adult inpatients	4
the day of	4
using the reported	4
time course of	4
attack rate of	4
of bias in	4
to explain the	4
target oxygen saturations	4
severity of a	4
suggested that the	4
university of washington	4
subway sarin attack	4
pandemic clinical severity	4
authors read and	4
it is clear	4
crude cfr of	4
distribution of cases	4
population level factors	4
appear in the	4
centre for mathematical	4
treatment of covid	4
studies reported outcomes	4
the epidemiology of	4
for a novel	4
by reported prevalence	4
incidence and the	4
representative for the	4
the vast majority	4
onset of the	4
the seven countries	4
supplemental oxygen in	4
for severe pandemics	4
shows that the	4
due to differences	4
the virus and	4
assume that the	4
with older populations	4
thought to be	4
in our analysis	4
from publicly reported	4
that convalescent plasma	4
how many people	4
country with a	4
j o u	4
rigorous social distancing	4
levels of protection	4
cumulative cases and	4
of symptoms to	4
is prone to	4
on april th	4
and did not	4
the cfr can	4
case of novel	4
for h n	4
between onset and	4
per person at	4
that of the	4
observational studies that	4
and it has	4
could be a	4
novel coronavirus outbreak	4
tokyo subway sarin	4
and death in	4
the overall cost	4
source of bias	4
infected with sars	4
st of march	4
of each individual	4
all infected persons	4
and prevalence of	4
our findings suggest	4
we use a	4
and it is	4
severity pandemics costs	4
males and females	4
optimal regression tree	4
and that the	4
the data of	4
cumulative incidence of	4
a patient with	4
adult inpatients with	4
of seasonal influenza	4
the age group	4
in italy and	4
number of known	4
diagnosis and treatment	4
of the reported	4
pneumonia in the	4
by productivity losses	4
data are available	4
in new york	4
were included in	4
model and the	4
have been used	4
an estimate for	4
republic of korea	4
and control dynamics	4
ratio of deaths	4
the values of	4
of influenza pneumonia	4
estimated as a	4
sex differences in	4
are a number	4
linear fit method	4
modelling of infectious	4
for the data	4
or hyperimmune immunoglobulin	4
the proposed model	4
for the public	4
given in table	4
based dashboard to	4
the first death	4
the wbf model	4
rest of the	4
p r e	4
reported confirmed cases	4
in the modelled	4
treatment with convalescent	4
the infection and	4
methods for estimating	4
a proportion of	4
other respiratory diseases	4
new york is	4
may result in	4
may be the	4
product of the	4
u r n	4
for systems science	4
care systems in	4
correction factor f	4
factors for mortality	4
on the internet	4
of the overall	4
performance of the	4
person compared to	4
can lead to	4
calculated the case	4
a relative cfr	4
in this issue	4
the agent is	4
by using the	4
cfr could be	4
should be noted	4
bias can be	4
after the th	4
positive cases in	4
a case and	4
diagnostic rate is	4
belgium data is	4
in contrast to	4
generated by arima	4
death from covid	4
who will die	4
countries with a	4
and the median	4
application of the	4
be used for	4
data is biased	4
evidence for a	4
the cause of	4
due to this	4
will have a	4
ranging from to	4
suggests that the	4
be higher in	4
r n a	4
in the data	4
of cases at	4
weak and negative	4
the lack of	4
the survival interval	4
in countries where	4
of individuals who	4
number of decomposition	4
a cohort of	4
first quarter of	4
and deaths and	4
in forecasted case	4
factors for the	4
which is a	4
order to understand	4
to death and	4
of the true	4
the form of	4
the high cfr	4
of deaths due	4
is essential to	4
the study is	4
is biased due	4
on public gatherings	4
countries with outbreak	4
per people in	4
differences between countries	4
disease in west	4
of the ifr	4
none of the	4
taken from the	4
be a more	4
as of march	4
of the curve	4
deaths in children	4
resulted in the	4
infected with novel	4
that would be	4
may affect the	4
the timing of	4
we present a	4
accordance with the	4
the site of	4
to note that	4
use of ppe	4
outbreak of covid	4
number of countries	4
specific attack rates	4
rate by at	4
proposed hybrid model	4
the evolution of	4
an optimal regression	4
highly effective interventions	4
cfr and r	4
at st march	4
for cases and	4
with severe symptoms	4
the first months	4
a certain date	4
of the tree	4
associated with death	4
to the th	4
of the analysis	4
to the pandemic	4
general population in	4
publicly reported confirmed	4
per person compared	4
plotted on the	4
the capacity of	4
cases on board	4
burden of a	4
with a delay	4
the case in	4
conflict of interest	4
protective effect of	4
between the time	4
most likely to	4
in children and	4
r o o	4
be used in	4
death or recovery	4
for decision making	4
patients with bacteremic	4
compared to no	4
coefficient of determination	4
a novel pathogen	4
the probability that	4
public health response	4
the speed of	4
serum in the	4
o u r	4
of the causal	4
higher cfr due	4
was assumed to	4
gross domestic product	4
costs arising from	4
the likelihood of	4
of a disease	3
the inflammatory response	3
timing of the	3
treatment of the	3
is assumed to	3
the work of	3
as a ratio	3
is the total	3
in which case	3
in this model	3
the hybrid model	3
to cope with	3
doubling days for	3
the first estimates	3
on severity and	3
to a country	3
pandemic influenza showed	3
many of these	3
of health workers	3
prognosis of these	3
for people with	3
of the two	3
countries have a	3
table shows an	3
of tests is	3
they are not	3
difference in ar	3
we show that	3
corona virus disease	3
of infection and	3
picture of the	3
the odds of	3
of transmission of	3
be defined as	3
conjunction with the	3
is more likely	3
time to recovery	3
school closure to	3
the validity of	3
be helpful to	3
in a region	3
a recent study	3
no comparative data	3
the true value	3
age distribution and	3
was not required	3
of global health	3
and the public	3
of these studies	3
showed quite different	3
in comparison with	3
convalescent serum in	3
duration of epidemic	3
of the actual	3
after th of	3
country centroid latitude	3
health outcomes across	3
interest is the	3
symptomatic cases using	3
a statistically significant	3
international health regulations	3
f journal pre	3
using the logarithm	3
explanations for the	3
is needed to	3
the association due	3
each intervention strategy	3
from that for	3
travel advisories of	3
of cfr in	3
is clear that	3
definition of the	3
by multiplying the	3
cost of any	3
have been able	3
fact that the	3
difference in the	3
from zero to	3
correlation with covid	3
that took place	3
a series of	3
death rate is	3
combination therapy with	3
pandemic potential of	3
a retrospective cohort	3
during the post	3
the reported deaths	3
for each severity	3
mortality rate is	3
the conditional probability	3
convalescent plasma in	3
linear regression analysis	3
to an underestimation	3
did not include	3
history of smoking	3
guidelines for when	3
period of coronavirus	3
substances emergency events	3
accuracy of the	3
proposed hybrid arima	3
sensitive to outliers	3
across countries and	3
survival interval adjusted	3
by johns hopkins	3
in most cases	3
corrected for the	3
related to a	3
in the test	3
in the main	3
the changes in	3
the database because	3
sex of male	3
age group as	3
believed to have	3
more than cases	3
of bias is	3
arising from productivity	3
heterogeneity for occupation	3
logistic regression analysis	3
can be regarded	3
there is still	3
a positive test	3
this rate is	3
of warning level	3
for selected other	3
more susceptible to	3
by the time	3
adjusted cfr varied	3
diagnosis and death	3
country specific differences	3
the epidemic curve	3
days of admission	3
an additional delay	3
pdm virus infection	3
public health threat	3
in a patient	3
countries with younger	3
fraction of people	3
we proceed to	3
the procedure for	3
we present the	3
deaths were reported	3
analysis is to	3
of patients who	3
data not shown	3
i would like	3
and smoking prevalence	3
the errors in	3
adjusted cfrs for	3
linear regression model	3
into account a	3
measures such as	3
reported use of	3
variables that are	3
older age of	3
is the probability	3
associated with cfr	3
chronic respiratory disease	3
system and the	3
greater than the	3
of a symptomatic	3
net benefit of	3
the combination of	3
of a strain	3
be useful in	3
than the number	3
underreporting of cases	3
medrxiv preprint figure	3
for the confirmed	3
the application of	3
to demonstrate the	3
light on the	3
a high risk	3
we did not	3
length of follow	3
for statistical computing	3
of deaths on	3
to ensure that	3
cases of coronavirus	3
high severity categories	3
by an infected	3
of oxygen in	3
for patient decontamination	3
with and without	3
analysis of patients	3
of infections is	3
by kou et	3
in an epidemic	3
led to the	3
fatalities due to	3
during day cycle	3
for the virus	3
the choice of	3
value for the	3
maximum group size	3
situations in which	3
for accurate and	3
calculated by dividing	3
of exponential growth	3
met our protocol	3
fatality of covid	3
in the german	3
and intensive care	3
reports of the	3
in treatment of	3
around the globe	3
this is also	3
cfr is also	3
detailed description of	3
identified before becoming	3
to our findings	3
severe chronic respiratory	3
estimating the infection	3
conditions such as	3
disease and cancer	3
for the adjusted	3
start after the	3
community infections is	3
albeit with a	3
if the number	3
number of daily	3
can be added	3
to increase the	3
may be much	3
cdc travel advisories	3
the real incidence	3
pandemic would be	3
to healthcare workers	3
is also the	3
cfr in italy	3
of the delay	3
a time delay	3
proportion of severe	3
the effects of	3
delay between reporting	3
it is of	3
severe and critical	3
calculated from aggregate	3
unit of time	3
severity and mortality	3
closure and community	3
the three different	3
all countries for	3
association between the	3
on march to	3
studies were at	3
median age of	3
administration of convalescent	3
pneumonia emergency response	3
ndpm than predicted	3
of the remaining	3
expectancy and quality	3
and lower than	3
studies of the	3
nature of the	3
likely to occur	3
the infectious period	3
increase the cfr	3
seem to be	3
studies suggest that	3
and recovered cases	3
up to october	3
due to various	3
outbreak in iran	3
countries using seroprevalence	3
the first problem	3
between female and	3
five pandemic severity	3
in the latter	3
the increment of	3
to societal disruption	3
on may th	3
of the three	3
as compared to	3
as occurred in	3
when we reviewed	3
daily tweets by	3
pages of the	3
indicate that the	3
of testing is	3
be the case	3
case of sars	3
substantial undocumented infection	3
would like to	3
the relation between	3
an indicator of	3
would be useful	3
expected number of	3
same type of	3
more than two	3
assuming that the	3
costs ranging from	3
of severe and	3
the mean of	3
top countries with	3
excluded from further	3
the true infection	3
outside of wuhan	3
by dividing the	3
findings for the	3
the surveillance data	3
for the optimal	3
indicating that the	3
alone is not	3
istituto superiore di	3
that significantly affect	3
be used as	3
which has been	3
current level of	3
enough testing capacity	3
and mortality of	3
the estimated effective	3
nd of march	3
of fatalities and	3
for the study	3
the reported number	3
in the period	3
the data were	3
deaths to total	3
such as smoking	3
to provide the	3
a multistep pattern	3
extent of the	3
country in the	3
for warm zone	3
the icu capacity	3
average number of	3
the adjusted post	3
an average age	3
the glamor project	3
must be considered	3
of clinical symptoms	3
cases in all	3
of people who	3
be an important	3
fraction of asymptomatic	3
is one of	3
may be affected	3
and may be	3
vast majority of	3
in the course	3
are less likely	3
the amount of	3
reporting of unconfirmed	3
incidence and case	3
for the remaining	3
into account detection	3
the republic of	3
reported data on	3
the ifr in	3
economic impact of	3
perlroth et al	3
total costs ranging	3
this does not	3
in this way	3
and the middle	3
with higher cfr	3
i t r	3
cohort of cases	3
for cfr in	3
of antiviral treatment	3
in the supplementary	3
emergency events surveillance	3
characteristics and outcomes	3
of infected persons	3
for ph n	3
higher in countries	3
to prevent infection	3
heterogeneity in the	3
no more than	3
the wider community	3
for outbreak duration	3
deaths per day	3
cases due to	3
possibly due to	3
will be higher	3
of the period	3
a total cost	3
significant in the	3
underestimate of the	3
to each other	3
modelling of the	3
would need to	3
time of the	3
and transparent health	3
of supplemental oxygen	3
on data availability	3
needs of resources	3
for each day	3
shape of the	3
beta distribution with	3
event history modelling	3
the disease at	3
appears to have	3
possible to use	3
and in a	3
allows us to	3
in this section	3
and group b	3
associated with lower	3
cases are identified	3
of washington model	3
should be taken	3
italy was the	3
from that in	3
but with a	3
that by the	3
and emergency response	3
the country in	3
in a database	3
rather than a	3
isolation of cases	3
health authorities are	3
is a potential	3
mean of days	3
accurate and transparent	3
target spo may	3
human transmission of	3
the first study	3
differences in infectious	3
to the case	3
to the following	3
the sum of	3
rate we must	3
high end of	3
citizens over years	3
package in r	3
to prevent transmission	3
relationship with age	3
target oxygen levels	3
rate in each	3
sampled from a	3
the median interval	3
parameters that may	3
than of the	3
subset of cases	3
of susceptible persons	3
real incidence of	3
ban on public	3
in a new	3
ranging from below	3
or as a	3
to those cases	3
causal impact of	3
position of the	3
societal disruption and	3
early stage of	3