This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
trigram | frequency |
---|---|
as well as | 1259 |
the presence of | 1068 |
in order to | 896 |
in this study | 708 |
one of the | 664 |
the development of | 621 |
the effect of | 573 |
in the presence | 551 |
the use of | 484 |
the treatment of | 479 |
the effects of | 464 |
based on the | 444 |
results suggest that | 439 |
the synthesis of | 437 |
the role of | 431 |
found to be | 431 |
the present study | 422 |
the expression of | 405 |
the activity of | 403 |
due to the | 401 |
involved in the | 389 |
the aim of | 379 |
activity of the | 374 |
was found to | 373 |
the formation of | 369 |
on the other | 361 |
it has been | 357 |
in the present | 350 |
the other hand | 349 |
to investigate the | 345 |
a series of | 336 |
compared to the | 332 |
the number of | 331 |
the production of | 321 |
these results suggest | 312 |
a number of | 299 |
role in the | 294 |
of this study | 287 |
for the treatment | 283 |
we found that | 281 |
is one of | 274 |
of the most | 263 |
in vitro and | 261 |
study was to | 260 |
a variety of | 259 |
this study was | 259 |
in patients with | 258 |
can be used | 253 |
the mechanism of | 250 |
been shown to | 248 |
isolated from the | 248 |
an important role | 247 |
in addition to | 246 |
according to the | 242 |
in terms of | 239 |
as a result | 236 |
and in vivo | 234 |
have shown that | 230 |
were found to | 229 |
important role in | 227 |
vitro and in | 224 |
has been shown | 222 |
the regulation of | 222 |
to determine the | 221 |
to be a | 216 |
suggest that the | 213 |
the activation of | 213 |
analysis of the | 212 |
to that of | 210 |
aim of this | 210 |
an increase in | 209 |
showed that the | 209 |
part of the | 208 |
the level of | 207 |
mechanism of action | 205 |
by means of | 205 |
as compared to | 203 |
the results of | 200 |
to study the | 199 |
well as the | 198 |
responsible for the | 198 |
used as a | 195 |
of the protein | 194 |
graduate school of | 193 |
structure of the | 192 |
of the peptide | 191 |
the importance of | 188 |
the inhibition of | 183 |
there is a | 183 |
shown to be | 183 |
antiviral activity of | 181 |
was used to | 181 |
changes in the | 179 |
wide range of | 178 |
results indicate that | 178 |
antimicrobial activity of | 177 |
the case of | 176 |
is involved in | 174 |
the structure of | 174 |
in response to | 174 |
are involved in | 173 |
in the brain | 173 |
the absence of | 173 |
the growth of | 173 |
the most potent | 170 |
we investigated the | 169 |
the influence of | 168 |
in the treatment | 167 |
most of the | 167 |
the amount of | 167 |
in this work | 167 |
of mannich bases | 166 |
in the case | 165 |
some of the | 164 |
to evaluate the | 163 |
was supported by | 162 |
in contrast to | 162 |
be involved in | 162 |
of these compounds | 161 |
a wide range | 161 |
mannich bases of | 160 |
results showed that | 158 |
increase in the | 158 |
the ability of | 157 |
and in the | 156 |
have been reported | 154 |
effect on the | 153 |
cancer cell lines | 152 |
found in the | 152 |
this work was | 152 |
was carried out | 152 |
related to the | 150 |
the ability to | 149 |
used for the | 149 |
found that the | 149 |
school of medicine | 148 |
such as the | 148 |
in which the | 148 |
than that of | 148 |
of action of | 148 |
associated with the | 148 |
observed in the | 147 |
for the synthesis | 147 |
used in the | 146 |
to be the | 145 |
activity in the | 145 |
in the same | 145 |
the design of | 144 |
the most active | 144 |
has been reported | 144 |
mode of action | 143 |
a role in | 142 |
it was found | 142 |
activation of the | 142 |
the addition of | 142 |
antibacterial activity of | 141 |
reactive oxygen species | 140 |
is associated with | 140 |
a and b | 140 |
effect of the | 139 |
of the enzyme | 139 |
for the development | 138 |
the active site | 138 |
we examined the | 137 |
with respect to | 137 |
in the absence | 135 |
effects of the | 135 |
the identification of | 135 |
be used as | 133 |
the application of | 133 |
a result of | 132 |
the levels of | 132 |
the in vitro | 132 |
depending on the | 132 |
known to be | 131 |
compared with the | 130 |
will be presented | 130 |
in the development | 130 |
that of the | 130 |
is based on | 130 |
be used to | 130 |
play an important | 130 |
central nervous system | 129 |
biological activity of | 129 |
were able to | 128 |
the interaction of | 128 |
the fact that | 128 |
neurons in the | 128 |
was used as | 128 |
the basis of | 127 |
been reported to | 127 |
in combination with | 127 |
the most common | 127 |
we show that | 126 |
in the regulation | 126 |
contribute to the | 126 |
was observed in | 126 |
was found that | 126 |
the majority of | 125 |
and in vitro | 124 |
expression of the | 124 |
due to its | 124 |
and characterization of | 124 |
amino acid residues | 124 |
is known to | 124 |
will be discussed | 123 |
were used to | 123 |
was shown to | 122 |
due to their | 122 |
the control group | 122 |
to understand the | 122 |
the function of | 121 |
is the most | 121 |
of the compounds | 120 |
the first day | 120 |
at the same | 119 |
cells in the | 119 |
that can be | 119 |
resulted in a | 119 |
more potent than | 118 |
seems to be | 118 |
properties of the | 117 |
has been used | 117 |
the binding of | 117 |
in the range | 116 |
the release of | 116 |
presence of a | 116 |
is an important | 116 |
the study of | 116 |
were carried out | 116 |
of the two | 116 |
revealed that the | 115 |
of the cell | 115 |
has also been | 115 |
herpes simplex virus | 114 |
which is a | 114 |
because of the | 113 |
on the basis | 113 |
was determined by | 112 |
role of the | 112 |
in comparison to | 112 |
the range of | 112 |
the control of | 112 |
these results indicate | 111 |
well as in | 110 |
a range of | 110 |
which can be | 110 |
large number of | 110 |
the end of | 110 |
we conclude that | 110 |
the amino acid | 110 |
present in the | 109 |
are known to | 109 |
at the c | 109 |
the surface of | 109 |
we have shown | 109 |
of the human | 109 |
is essential for | 109 |
a decrease in | 109 |
their ability to | 108 |
presence of the | 108 |
the relationship between | 107 |
of patients with | 107 |
aim of the | 107 |
are able to | 107 |
the most important | 106 |
in the study | 106 |
proved to be | 105 |
there was no | 105 |
the process of | 105 |
show that the | 105 |
the impact of | 105 |
has not been | 105 |
the plasma membrane | 104 |
supported by the | 104 |
inhibition of the | 104 |
the rate of | 103 |
understanding of the | 103 |
to identify the | 102 |
position of the | 102 |
the detection of | 102 |
mechanisms of action | 102 |
results show that | 101 |
the pathogenesis of | 101 |
the antiviral activity | 101 |
in the rat | 101 |
work was supported | 101 |
shown that the | 101 |
indicate that the | 101 |
be used for | 101 |
expressed in the | 101 |
the nature of | 100 |
of amino acids | 100 |
the analysis of | 100 |
this study is | 99 |
studies showed that | 99 |
play a role | 99 |
for the first | 99 |
a combination of | 99 |
in a dose | 99 |
the concentration of | 99 |
when compared to | 98 |
was to investigate | 98 |
it was shown | 97 |
of psoralea corylifolia | 97 |
be used in | 96 |
were treated with | 96 |
a set of | 96 |
have been used | 96 |
of the present | 96 |
the discovery of | 96 |
the introduction of | 96 |
function of the | 96 |
studies have shown | 95 |
have been shown | 95 |
antiviral activity against | 95 |
the same time | 95 |
we aimed to | 95 |
the induction of | 95 |
to increase the | 95 |
led to the | 94 |
antifungal activity of | 94 |
is required for | 94 |
the purpose of | 94 |
is able to | 94 |
there is no | 94 |
nature of the | 93 |
to improve the | 93 |
of a new | 93 |
present study was | 93 |
in the control | 93 |
inhibitory activity against | 92 |
demonstrated that the | 92 |
in recent years | 92 |
the interaction between | 91 |
a large number | 91 |
the lack of | 91 |
it is possible | 91 |
all of the | 91 |
characterization of the | 91 |
study is to | 91 |
in the last | 90 |
were isolated from | 90 |
on the surface | 90 |
member of the | 90 |
be due to | 90 |
the first time | 90 |
data suggest that | 90 |
were determined by | 89 |
a total of | 89 |
compared to control | 88 |
inhibitory activity of | 88 |
indicated that the | 88 |
it can be | 88 |
did not show | 87 |
a concentration of | 87 |
plays an important | 87 |
the results showed | 87 |
bases derived from | 87 |
the antibacterial activity | 87 |
derived from the | 86 |
different types of | 86 |
the generation of | 86 |
the biological activity | 86 |
it is a | 86 |
we have developed | 86 |
studies on the | 86 |
is responsible for | 86 |
focused on the | 85 |
this study we | 85 |
mannich bases derived | 85 |
differences in the | 85 |
to inhibit the | 85 |
to elucidate the | 85 |
the action of | 85 |
our results suggest | 85 |
of essential oils | 85 |
the th day | 85 |
antioxidant activity of | 84 |
evaluation of the | 84 |
to assess the | 84 |
but not in | 84 |
at the end | 83 |
as a model | 83 |
of the peptides | 82 |
a mixture of | 82 |
at a concentration | 82 |
of a novel | 82 |
to examine the | 82 |
similar to that | 82 |
the involvement of | 82 |
was shown that | 81 |
reported to be | 81 |
in vivo and | 81 |
materials and methods | 81 |
for treatment of | 81 |
of the c | 81 |
was found in | 81 |
decrease in the | 80 |
end of the | 80 |
the efficacy of | 80 |
in the human | 80 |
and can be | 80 |
to be more | 80 |
amino acid sequence | 80 |
to the first | 80 |
of the n | 80 |
the combination of | 80 |
to reduce the | 80 |
the course of | 80 |
the preparation of | 80 |
have been identified | 80 |
the increase in | 79 |
the evaluation of | 79 |
were found in | 79 |
been found to | 79 |
binding to the | 79 |
is known about | 79 |
were observed in | 79 |
a group of | 79 |
was the most | 79 |
may contribute to | 79 |
appears to be | 79 |
the possibility of | 79 |
have been found | 78 |
the central nervous | 78 |
have also been | 78 |
we report the | 78 |
rna chaperone activity | 78 |
obtained from the | 78 |
could be used | 78 |
are associated with | 77 |
effects on the | 77 |
in the first | 77 |
the cell membrane | 77 |
there was a | 77 |
to be involved | 77 |
suggested that the | 77 |
region of the | 76 |
we showed that | 76 |
based on a | 76 |
the present work | 76 |
and mg kg | 76 |
amino acids and | 75 |
is the first | 75 |
regulation of the | 75 |
results indicated that | 75 |
this is the | 75 |
we have previously | 75 |
components of the | 75 |
members of the | 75 |
has been found | 75 |
be able to | 75 |
in the cell | 75 |
in the literature | 74 |
dependent on the | 74 |
the risk of | 74 |
a member of | 74 |
in case of | 74 |
of the study | 74 |
the frequency of | 74 |
results of the | 74 |
phase peptide synthesis | 74 |
inhibitory effect of | 74 |
the determination of | 73 |
have been developed | 73 |
be related to | 73 |
and evaluation of | 73 |
interaction with the | 73 |
been shown that | 73 |
hepatitis c virus | 73 |
for this purpose | 73 |
carried out in | 73 |
of the essential | 72 |
the immune system | 72 |
led to a | 72 |
be responsible for | 72 |
development of new | 72 |
from the marine | 72 |
the study was | 72 |
was isolated from | 72 |
in this context | 72 |
were used for | 71 |
oxidative stress and | 71 |
in the pathogenesis | 71 |
suggests that the | 71 |
depends on the | 71 |
to play a | 71 |
study of the | 71 |
signi fi cantly | 71 |
in comparison with | 71 |
a dose of | 71 |
suggesting that the | 71 |
and biological evaluation | 70 |
the mechanisms of | 70 |
the molecular mechanisms | 70 |
little is known | 70 |
the cell surface | 70 |
university of tokyo | 70 |
some of these | 70 |
of mg kg | 70 |
and it is | 70 |
investigation of the | 70 |
synthesis and biological | 70 |
were shown to | 70 |
of the same | 70 |
may be a | 70 |
is expressed in | 70 |
mechanism of the | 70 |
in our study | 69 |
department of physiology | 69 |
the degree of | 69 |
are responsible for | 69 |
active site of | 69 |
for the production | 69 |
the compounds were | 69 |
activity of a | 69 |
a key role | 69 |
it is also | 69 |
which is the | 69 |
antibacterial activity against | 69 |
development of a | 69 |
formation of the | 69 |
change in the | 68 |
required for the | 68 |
the activities of | 68 |
considered to be | 68 |
addition to the | 68 |
of the major | 68 |
did not affect | 68 |
the synthesis and | 68 |
phenolic mannich bases | 68 |
activity against the | 67 |
biological evaluation of | 67 |
an increase of | 67 |
at position of | 67 |
also known as | 67 |
we developed a | 67 |
activities of the | 67 |
was used for | 67 |
been used to | 67 |
to interact with | 67 |
similar to the | 67 |
key role in | 67 |
gene expression in | 67 |
is thought to | 67 |
lead to the | 67 |
at a dose | 66 |
is a major | 66 |
in the hippocampus | 66 |
breast cancer cells | 66 |
in the central | 66 |
the stability of | 66 |
be associated with | 66 |
it is known | 66 |
of these peptides | 66 |
inhibitory effect on | 66 |
new class of | 66 |
no effect on | 66 |
stability of the | 66 |
essential for the | 65 |
none of the | 65 |
to those of | 65 |
use of the | 65 |
to analyze the | 65 |
with ic values | 65 |
in relation to | 65 |
is used to | 65 |
some of them | 65 |
science and technology | 65 |
of reactive oxygen | 65 |
can also be | 65 |
marine natural products | 65 |
was able to | 65 |
thought to be | 65 |
the changes in | 65 |
by using the | 65 |
characterized by a | 65 |
is important for | 64 |
of our study | 64 |
we studied the | 64 |
findings suggest that | 64 |
of the target | 64 |
as shown in | 64 |
we analyzed the | 64 |
the most effective | 64 |
the results suggest | 64 |
were used as | 64 |
activity of these | 64 |
determination of the | 64 |
formation of a | 64 |
found to have | 64 |
the onset of | 63 |
comparison of the | 63 |
national institute of | 63 |
to the control | 63 |
in vitro activity | 63 |
for the design | 63 |
the distribution of | 63 |
the wild type | 63 |
located in the | 63 |
the antioxidant activity | 63 |
because of their | 63 |
the loss of | 63 |
significant increase in | 63 |
is characterized by | 63 |
low molecular weight | 63 |
the potential of | 63 |
oral administration of | 62 |
aim of our | 62 |
the results obtained | 62 |
in our laboratory | 62 |
to be used | 62 |
is related to | 62 |
a significant increase | 62 |
and its derivatives | 62 |
belongs to the | 62 |
here we report | 62 |
crystal structure of | 62 |
we have recently | 62 |
the increase of | 62 |
in presence of | 62 |
of the viral | 62 |
activity in vitro | 62 |
carried out by | 61 |
of natural products | 61 |
the university of | 61 |
ic value of | 61 |
structures of the | 61 |
blood samples were | 61 |
the type of | 61 |
day compared to | 61 |
have not been | 61 |
caused by the | 61 |
an in vitro | 61 |
than in the | 61 |
ic values of | 61 |
between the two | 61 |
it is not | 61 |
a family of | 60 |
tumor necrosis factor | 60 |
the context of | 60 |
in situ hybridization | 60 |
we were able | 60 |
are the most | 60 |
amino acids in | 60 |
results suggested that | 60 |
of pomegranate juice | 60 |
the potential to | 60 |
for the detection | 60 |
and on the | 60 |
were obtained from | 60 |
were analyzed by | 59 |
we are currently | 59 |
of the virus | 59 |
the existence of | 59 |
important for the | 59 |
importance of the | 59 |
were the most | 59 |
as the most | 59 |
human immunodeficiency virus | 59 |
development of the | 59 |
at the n | 59 |
of this work | 59 |
leads to the | 59 |
the proliferation of | 59 |
as a consequence | 59 |
were synthesized by | 59 |
leading to the | 59 |
was associated with | 59 |
the extent of | 59 |
with regard to | 59 |
with an ic | 59 |
that have been | 59 |
has been demonstrated | 59 |
that there is | 58 |
of the proteins | 58 |
isolated from a | 58 |
was detected in | 58 |
information on the | 58 |
were tested for | 58 |
of the amino | 58 |
residues in the | 58 |
was measured by | 58 |
the essential oil | 58 |
cell death in | 58 |
results in the | 58 |
to clarify the | 58 |
reduction of the | 58 |
serve as a | 58 |
dose of mg | 58 |
and that the | 58 |
before and after | 58 |
to characterize the | 58 |
method for the | 58 |
is a potent | 58 |
was added to | 58 |
increase of the | 57 |
added to the | 57 |
the antimicrobial activity | 57 |
acts as a | 57 |
in the past | 57 |
the mannich reaction | 57 |
together with the | 57 |
the most promising | 57 |
were detected in | 57 |
the in vivo | 57 |
due to a | 57 |
interact with the | 57 |
the accumulation of | 57 |
we propose that | 57 |
the search for | 57 |
followed by a | 57 |
expression in the | 57 |
of punica granatum | 57 |
signi fi cant | 57 |
when compared with | 56 |
resulted in the | 56 |
studies of the | 56 |
by using a | 56 |
molecular mechanisms of | 56 |
to have a | 56 |
is possible to | 56 |
in the field | 56 |
associated with a | 56 |
as a potential | 56 |
and biological activity | 56 |
of a series | 56 |
of cordyceps sinensis | 56 |
consistent with the | 56 |
is a key | 56 |
we have investigated | 55 |
synthesis of a | 55 |
in the context | 55 |
synthesis of the | 55 |
had no effect | 55 |
detected in the | 55 |
oxidative stress in | 55 |
the characterization of | 55 |
comparable to that | 55 |
of the membrane | 55 |
to the presence | 55 |
that it is | 55 |
and antimicrobial activity | 55 |
of gene expression | 55 |
reported that the | 55 |
broad spectrum of | 55 |
we have identified | 55 |
of the activity | 55 |
mg kg day | 55 |
linked to the | 55 |
purpose of this | 55 |
a crucial role | 55 |
is due to | 55 |
only in the | 54 |
of antimicrobial peptides | 54 |
in the formation | 54 |
is important to | 54 |
data indicate that | 54 |
the sequence of | 54 |
is mediated by | 54 |
basis of the | 54 |
of reference drug | 54 |
is known that | 54 |
of the cells | 54 |
of amino acid | 54 |
control of the | 54 |
with that of | 54 |
attached to the | 54 |
and found that | 54 |
from psoralea corylifolia | 54 |
was applied to | 54 |
parts of the | 54 |
we used the | 54 |
high levels of | 54 |
is composed of | 54 |
the cytotoxicity of | 54 |
of the first | 54 |
in the liver | 53 |
correlated with the | 53 |
to test the | 53 |
showed the highest | 53 |
it should be | 53 |
m g ml | 53 |
corresponding to the | 53 |
hepatitis b virus | 53 |
was confirmed by | 53 |
of the active | 53 |
i and ii | 53 |
biological activities of | 53 |
to the development | 53 |
have demonstrated that | 53 |
to be an | 53 |
a new class | 53 |
levels of the | 53 |
surface of the | 53 |
may lead to | 53 |
of the disease | 53 |
the form of | 53 |
in the mouse | 53 |
indicating that the | 53 |
could be a | 53 |
solid phase peptide | 53 |
was performed by | 53 |
academy of sciences | 53 |
protective effect of | 53 |
were performed in | 53 |
each of the | 53 |
diseases such as | 53 |
the reduction of | 53 |
composition of the | 53 |
expression levels of | 52 |
analysis revealed that | 52 |
are present in | 52 |
part of a | 52 |
a reduction in | 52 |
than reference drug | 52 |
it is well | 52 |
and synthesis of | 52 |
the essential oils | 52 |
there were no | 52 |
in the form | 52 |
to explore the | 51 |
in some cases | 51 |
of the compound | 51 |
vivo and in | 51 |
of more than | 51 |
reduction in the | 51 |
activity of some | 51 |
were exposed to | 51 |
sequence of the | 51 |
in escherichia coli | 51 |
significantly higher in | 51 |
on the cell | 51 |
that in the | 51 |
leads to a | 51 |
these findings suggest | 51 |
in the future | 51 |
and function of | 51 |
the need for | 51 |
the reaction of | 51 |
was assessed by | 51 |
as in the | 51 |
insight into the | 51 |
able to inhibit | 51 |
has been proposed | 51 |
the incidence of | 50 |
used as an | 50 |
to develop a | 50 |
has been developed | 50 |
the fi rst | 50 |
group of the | 50 |
is regulated by | 50 |
the seeds of | 50 |
ability to inhibit | 50 |
antifungal activity against | 50 |
western blot analysis | 50 |
cancer cell line | 50 |
activity of mannich | 50 |
characterization of a | 50 |
the position of | 50 |
many of the | 50 |
more active than | 50 |
the current study | 50 |
to the cell | 50 |
the result of | 50 |
included in the | 50 |
we have used | 50 |
the inhibitory effect | 50 |
in the synthesis | 50 |
we have found | 50 |
belonging to the | 50 |
based on these | 50 |
of the three | 50 |
appear to be | 50 |
it is important | 50 |
with a high | 49 |
university graduate school | 49 |
be considered as | 49 |
protein kinase c | 49 |
be useful in | 49 |
be the most | 49 |
interaction of the | 49 |
designed and synthesized | 49 |
have been isolated | 49 |
of in vitro | 49 |
higher than that | 49 |
of the test | 49 |
potent inhibitors of | 49 |
to the formation | 49 |
antimicrobial activity against | 49 |
wide variety of | 49 |
have to be | 49 |
differences between the | 49 |
department of chemical | 49 |
be attributed to | 49 |
aimed to investigate | 49 |
in a variety | 49 |
in the early | 49 |
is used as | 49 |
used to treat | 49 |
and development of | 48 |
modification of the | 48 |
the investigation of | 48 |
been associated with | 48 |
a consequence of | 48 |
analysis was performed | 48 |
contrast to the | 48 |
a panel of | 48 |
in the adult | 48 |
recent studies have | 48 |
as compared with | 48 |
and of the | 48 |
in vitro studies | 48 |
is caused by | 48 |
crucial role in | 48 |
tested for their | 48 |
has been suggested | 48 |
antibacterial and antifungal | 48 |
results of this | 48 |
our results show | 48 |
stimulation of the | 48 |
the ratio of | 48 |
contributes to the | 48 |
physical activity and | 48 |
on the first | 48 |
were synthesized and | 48 |
the incorporation of | 47 |
the performance of | 47 |
were measured by | 47 |
were significantly higher | 47 |
of this enzyme | 47 |
influence of the | 47 |
inhibitory effects of | 47 |
here we present | 47 |
been isolated from | 47 |
the time of | 47 |
we used a | 47 |
knowledge of the | 47 |
activity was observed | 47 |
the size of | 47 |
of the main | 47 |
as a novel | 47 |
more than of | 47 |
likely to be | 47 |
important roles in | 47 |
the conversion of | 47 |
the isolation of | 47 |
peptides and proteins | 47 |
positive and gram | 47 |
to form a | 47 |
which could be | 47 |
as determined by | 47 |
has to be | 47 |
as amine reagents | 47 |
of the tested | 47 |
state of the | 47 |
the united states | 47 |
the hydrolysis of | 47 |
mutations in the | 46 |
learning and memory | 46 |
major role in | 46 |
in vitro anti | 46 |
no significant difference | 46 |
as a new | 46 |
cells of the | 46 |
one or more | 46 |
by the presence | 46 |
may play a | 46 |
we have studied | 46 |
of the new | 46 |
was performed using | 46 |
to be effective | 46 |
and has been | 46 |
antimicrobial activities of | 46 |
was investigated by | 46 |
insights into the | 46 |
were used in | 46 |
site of the | 46 |
the value of | 46 |
inhibitors of the | 46 |
the replication of | 46 |
of the gene | 46 |
induced by the | 46 |
component of the | 46 |
we have also | 46 |
is well known | 46 |
point of view | 46 |
we present the | 46 |
an inhibitor of | 46 |
higher than the | 46 |
of them are | 45 |
step in the | 45 |
university school of | 45 |
a part of | 45 |
the first step | 45 |
of the plant | 45 |
characteristics of the | 45 |
applied to the | 45 |
length of the | 45 |
in this series | 45 |
have investigated the | 45 |
the cells were | 45 |
institute of technology | 45 |
seem to be | 45 |
are used in | 45 |
there is an | 45 |
that the presence | 45 |
study was supported | 45 |
resulting in the | 45 |
and inhibition of | 45 |
these compounds were | 45 |
a wide variety | 45 |
in the process | 45 |
the quality of | 45 |
known about the | 45 |
as part of | 45 |
activity against a | 45 |
and some of | 45 |
have been studied | 45 |
the results indicated | 45 |
p and p | 45 |
can be applied | 45 |
smooth muscle cells | 45 |
its ability to | 45 |
binding of the | 45 |
shown to have | 45 |
we demonstrated that | 45 |
but also in | 44 |
the last years | 44 |
could not be | 44 |
in the blood | 44 |
of eucalyptus camaldulensis | 44 |
and may be | 44 |
and identification of | 44 |
of the brain | 44 |
concentrations of the | 44 |
which may be | 44 |
out of the | 44 |
in the current | 44 |
allowed us to | 44 |
genes involved in | 44 |
for use in | 44 |
the inhibitory activity | 44 |
group at the | 44 |
at room temperature | 44 |
li et al | 44 |
the possibility to | 44 |
and the other | 44 |
amino acid sequences | 44 |
not only in | 44 |
as inhibitors of | 44 |
the rhizomes of | 44 |
that has been | 44 |
tandem mass spectrometry | 44 |
pomegranate fruit extract | 44 |
also in the | 44 |
in the active | 44 |
that of reference | 44 |
psoralea corylifolia l | 44 |
levels in the | 44 |
action of the | 44 |
the structure and | 44 |
structure and function | 44 |
molecular weight of | 44 |
were incubated with | 44 |
results demonstrate that | 44 |
the length of | 44 |
structural and functional | 44 |
a critical role | 44 |
of the different | 44 |
a broad spectrum | 44 |
was evaluated by | 43 |
regions of the | 43 |
expression level of | 43 |
may be involved | 43 |
this class of | 43 |
work was to | 43 |
concentration of the | 43 |
were subjected to | 43 |
which has been | 43 |
at least one | 43 |
synthesized a series | 43 |
a class of | 43 |
proven to be | 43 |
analysis showed that | 43 |
the mode of | 43 |
a model of | 43 |
been used as | 43 |
in accordance with | 43 |
results revealed that | 43 |
implicated in the | 43 |
of physical activity | 43 |
of the patients | 43 |
removal of the | 43 |
an attempt to | 43 |
the secondary structure | 43 |
cell proliferation and | 43 |
because of its | 43 |
department of chemistry | 43 |
the tested compounds | 43 |
were divided into | 43 |
molecular dynamics simulations | 43 |
the interaction with | 43 |
relationship between the | 43 |
respect to the | 43 |
is crucial for | 43 |
may be useful | 43 |
domain of the | 43 |
the concept of | 43 |
in agreement with | 43 |
the synthesized compounds | 43 |
the crystal structure | 42 |
the hypothesis that | 42 |
the modulation of | 42 |
we present a | 42 |
breast cancer cell | 42 |
these data suggest | 42 |
an ic value | 42 |
were obtained by | 42 |
mediated by the | 42 |
data on the | 42 |
this type of | 42 |
of biological activities | 42 |
in the second | 42 |
result of the | 42 |
in spite of | 42 |
potent and selective | 42 |
order to investigate | 42 |
were performed on | 42 |
the spinal cord | 42 |
the contribution of | 42 |
half of the | 42 |
two types of | 42 |
synthesis of novel | 42 |
need to be | 42 |
is present in | 42 |
proteins involved in | 42 |
on the activity | 42 |
influence on the | 42 |
in the developing | 42 |
be useful for | 42 |
of the rat | 42 |
was studied in | 42 |
severe acute respiratory | 42 |
those of the | 42 |
been used for | 42 |
of the interaction | 42 |
compared to that | 42 |
in animal models | 42 |
is necessary to | 42 |
was expressed in | 42 |
is dependent on | 42 |
needs to be | 41 |
values in the | 41 |
to obtain the | 41 |
the objective of | 41 |
surface plasmon resonance | 41 |
the results were | 41 |
activities in the | 41 |
to bind to | 41 |
of the complex | 41 |
based on their | 41 |
a major role | 41 |
been used in | 41 |
the percentage of | 41 |
of the dna | 41 |
is the major | 41 |
design and synthesis | 41 |
was performed in | 41 |
activity and the | 41 |
it was also | 41 |
peptides derived from | 41 |
in this review | 41 |
the age of | 41 |
this work is | 41 |
were investigated in | 41 |
during the first | 41 |
correlation between the | 41 |
present study we | 41 |
for the study | 41 |
and activation of | 41 |
higher in the | 41 |
in the following | 41 |
ability of the | 41 |
can lead to | 41 |
the composition of | 41 |
under the control | 41 |
the field of | 41 |
are essential for | 41 |
and it was | 41 |
than those of | 41 |
the cell cycle | 41 |
acute respiratory syndrome | 41 |
close to the | 41 |
this work we | 41 |
a decrease of | 41 |
our results indicate | 41 |
we observed that | 41 |
a reduction of | 40 |
size of the | 40 |
well as a | 40 |
difference in the | 40 |
have been synthesized | 40 |
at the level | 40 |
the antifungal activity | 40 |
here we show | 40 |
the biosynthesis of | 40 |
nitric oxide synthase | 40 |
it was observed | 40 |
interest in the | 40 |
the management of | 40 |
a source of | 40 |
children and adolescents | 40 |
studies have been | 40 |
appeared to be | 40 |
a period of | 40 |
to reference drug | 40 |
and as a | 40 |
in a single | 40 |
activity against m | 40 |
prostate cancer cells | 40 |
investigated the effects | 40 |
used to determine | 40 |
expressed in e | 40 |
attributed to the | 40 |
aim is to | 40 |
was induced by | 40 |
were more potent | 40 |
the structures of | 40 |
is part of | 40 |
levels were measured | 40 |
synthesis and in | 40 |
are used as | 40 |
of a single | 40 |
to enhance the | 40 |
was designed to | 40 |
the effectiveness of | 40 |
is that the | 40 |
of a protein | 40 |
a review of | 40 |
application of the | 40 |
of chemical engineering | 40 |
we suggest that | 40 |
from patients with | 40 |
high degree of | 40 |
brain science institute | 40 |
were identified by | 40 |
we have been | 39 |
the uptake of | 39 |
wang et al | 39 |
characterized by the | 39 |
as one of | 39 |
the enzyme activity | 39 |
we demonstrate that | 39 |
department of molecular | 39 |
the possibility that | 39 |
are expressed in | 39 |
kg body weight | 39 |
been reported that | 39 |
to obtain a | 39 |
simplex virus type | 39 |
with the use | 39 |
indicates that the | 39 |
potential of the | 39 |
were determined in | 39 |
have developed a | 39 |
lee et al | 39 |
were compared with | 39 |
by mass spectrometry | 39 |
levels were significantly | 39 |
similar to those | 39 |
significant differences in | 39 |
have been described | 39 |
on the use | 39 |
to determine whether | 39 |
more than one | 39 |
the properties of | 39 |
interaction between the | 39 |
the results show | 39 |
was observed for | 39 |
spinal cord injury | 39 |
reported in the | 39 |
in vitro antiviral | 39 |
of the total | 39 |
increased in the | 39 |
with those of | 39 |
interactions between the | 39 |
in vivo studies | 39 |
in cell culture | 39 |
of the a | 39 |
small number of | 39 |
have found that | 39 |
pharmakologie und toxikologie | 39 |
of the synthesized | 39 |
is supported by | 39 |
carried out on | 39 |
the kinetics of | 39 |
compounds were tested | 39 |
in this way | 39 |
identification of the | 39 |
roles in the | 38 |
the group of | 38 |
of these proteins | 38 |
are found in | 38 |
of at least | 38 |
pomegranate seed oil | 38 |
was investigated in | 38 |
considered as a | 38 |
lower than that | 38 |
there are several | 38 |
of the molecule | 38 |
is necessary for | 38 |
and the lowest | 38 |
level of the | 38 |
in most cases | 38 |
values of the | 38 |
from a marine | 38 |
in the production | 38 |
most of them | 38 |
were investigated by | 38 |
to reveal the | 38 |
to be active | 38 |
investigated the effect | 38 |
conclude that the | 38 |
enzymes involved in | 38 |
necessary for the | 38 |
the toxicity of | 38 |
were prepared by | 38 |
along with the | 38 |
at least in | 38 |
the rest of | 38 |
inhibit the growth | 38 |
the yoghurt sample | 38 |
and for the | 38 |
majority of the | 38 |
not affect the | 38 |
of them were | 38 |
are thought to | 38 |
ketonic mannich bases | 38 |
punica granatum l | 38 |
we report that | 38 |
difference between the | 38 |
affected by the | 38 |
human umbilical vein | 38 |
in the series | 38 |
better understanding of | 38 |
critical role in | 38 |
broad range of | 38 |
in the course | 38 |
in breast cancer | 38 |
found to inhibit | 38 |
in an attempt | 38 |
in the number | 38 |
a function of | 38 |
reported to have | 38 |
are characterized by | 38 |
of all the | 38 |
has been identified | 38 |
compared to those | 38 |
was inhibited by | 37 |
that may be | 37 |
in the nucleus | 37 |
a lack of | 37 |
the aromatic ring | 37 |
of molecular biology | 37 |
results in a | 37 |
were expressed in | 37 |
in this case | 37 |
in the n | 37 |
in regulation of | 37 |
performance liquid chromatography | 37 |
in physical activity | 37 |
for in vitro | 37 |
of the molecular | 37 |
of the antimicrobial | 37 |
c and c | 37 |
its interaction with | 37 |
to be able | 37 |
the interactions between | 37 |
risk factor for | 37 |
the removal of | 37 |
the protein was | 37 |
a significant decrease | 37 |
are based on | 37 |
to compare the | 37 |
factors such as | 37 |
is a novel | 37 |
national institute for | 37 |
molecular mechanism of | 37 |
of these two | 37 |
for this reason | 37 |
which have been | 37 |
department of biology | 37 |
of the genus | 37 |
the basis for | 37 |
and the results | 37 |
polymerase chain reaction | 37 |
potent inhibitor of | 37 |
was higher than | 37 |
we focused on | 37 |
of the central | 37 |
of the native | 37 |
in mammalian cells | 37 |
in the plasma | 37 |
for the activity | 37 |
but it is | 37 |
all of these | 37 |
with the same | 37 |
is similar to | 37 |
the content of | 37 |
distribution of the | 37 |
was identified as | 37 |
is used for | 36 |
been implicated in | 36 |
we found a | 36 |
not show any | 36 |
of the resulting | 36 |
the change in | 36 |
replacement of the | 36 |
the nervous system | 36 |
significant reduction in | 36 |
traditional chinese medicine | 36 |
with the aim | 36 |
from the seeds | 36 |
can be obtained | 36 |
for the preparation | 36 |
have been investigated | 36 |
it was demonstrated | 36 |
these results are | 36 |
belong to the | 36 |
the goal of | 36 |
compared to other | 36 |
has led to | 36 |
of the p | 36 |
by measuring the | 36 |
significant decrease in | 36 |
in living cells | 36 |
be applied to | 36 |
compounds have been | 36 |
umbilical vein endothelial | 36 |
in aqueous solution | 36 |
to form the | 36 |
the degradation of | 36 |
resistant staphylococcus aureus | 36 |
was performed on | 36 |
at mg kg | 36 |
is likely to | 36 |
the occurrence of | 36 |
activity compared to | 36 |
kim et al | 36 |
been found in | 36 |
used as the | 36 |
the metabolism of | 36 |
the decrease of | 36 |
to control the | 36 |
in the primary | 36 |
cells in vitro | 36 |
the leaves of | 36 |
will be used | 36 |
the problem of | 36 |
at the time | 36 |
of the corresponding | 36 |
used to study | 36 |
act as a | 36 |
modulation of the | 36 |
it is necessary | 36 |
and amino acid | 36 |
is a common | 36 |
identified as a | 36 |
inhibitor of the | 36 |
determined by the | 36 |
were evaluated by | 36 |
mrna and protein | 36 |
are required for | 36 |
this is a | 36 |
carried out using | 36 |
is believed to | 36 |
can be found | 36 |
in the design | 35 |
is a highly | 35 |
significant difference between | 35 |
is to investigate | 35 |
has been observed | 35 |
as an alternative | 35 |
were included in | 35 |
examined the effects | 35 |
as shown by | 35 |
inhibitory effects on | 35 |
of oxidative stress | 35 |
the last decade | 35 |
in the heart | 35 |
neural stem cells | 35 |
in this process | 35 |
structure of a | 35 |
agreement with the | 35 |
from the same | 35 |
leading to a | 35 |
specificity of the | 35 |
to measure the | 35 |
the molecular mechanism | 35 |
extract of the | 35 |
according to their | 35 |
produced by the | 35 |
radical scavenging activity | 35 |
for the identification | 35 |
response to the | 35 |
the selection of | 35 |
fold increase in | 35 |
evaluated for their | 35 |
to the high | 35 |
be noted that | 35 |
human breast cancer | 35 |
compounds in the | 35 |
in complex with | 35 |
may not be | 35 |
of the receptor | 35 |
the substitution of | 35 |
been suggested that | 35 |
and mg ml | 35 |
studies revealed that | 35 |
study on the | 35 |
was to evaluate | 35 |
by western blot | 35 |
the side chain | 35 |
one of these | 35 |
the replacement of | 35 |
molecular docking studies | 35 |
was to determine | 35 |
in the expression | 35 |
by addition of | 35 |
study showed that | 35 |
and treatment of | 35 |
in the group | 35 |
our results showed | 35 |
the construction of | 35 |
binding site of | 35 |
the results indicate | 35 |
involvement of the | 35 |
has been studied | 35 |
with the control | 35 |
which in turn | 35 |
form of the | 35 |
aim was to | 34 |
production of the | 34 |
presence or absence | 34 |
we describe the | 34 |
profile of the | 34 |
the sensitivity of | 34 |
yang et al | 34 |
essential oils and | 34 |
the severity of | 34 |
the efficiency of | 34 |
and antimicrobial activities | 34 |
significant difference in | 34 |
widely used in | 34 |
in this presentation | 34 |
was performed to | 34 |
play important roles | 34 |
or absence of | 34 |
was obtained by | 34 |
the most abundant | 34 |
studies were performed | 34 |
cleavage of the | 34 |
its role in | 34 |
treatment of the | 34 |
in a similar | 34 |
activity in a | 34 |
the administration of | 34 |
information about the | 34 |
and antiviral activities | 34 |
of the binding | 34 |
in a mouse | 34 |
by increasing the | 34 |
demonstrate that the | 34 |
resulting in a | 34 |
a subset of | 34 |
the correlation between | 34 |
any of the | 34 |
of which are | 34 |
a potent inhibitor | 34 |
is a member | 34 |
there are no | 34 |
was significantly higher | 34 |
of science and | 34 |
in the ca | 34 |
we have demonstrated | 34 |
in a concentration | 34 |
receptors in the | 34 |
derivatives synthesis and | 34 |
essential oil of | 34 |
induction of apoptosis | 34 |
amino acids were | 34 |
in another study | 34 |
not yet been | 34 |
a mouse model | 34 |
was based on | 34 |
and oxidative stress | 34 |
liu et al | 34 |
a change in | 34 |
we compared the | 34 |
model of the | 34 |
antiviral activities of | 34 |
is considered to | 34 |
be found in | 34 |
a lot of | 34 |
from the brown | 34 |
play a key | 34 |
are widely used | 33 |
the phenyl ring | 33 |
features of the | 33 |
it could be | 33 |
depend on the | 33 |
the method of | 33 |
in a number | 33 |
the binding site | 33 |
different concentrations of | 33 |
development of novel | 33 |
in cancer cells | 33 |
the cleavage of | 33 |
the progression of | 33 |
our study was | 33 |
the enzyme was | 33 |
to be associated | 33 |
was reported to | 33 |
the separation of | 33 |
compounds isolated from | 33 |
as amine reagent | 33 |
department of pharmacology | 33 |
was determined in | 33 |
encapsulated in sodium | 33 |
comparison with the | 33 |
the specificity of | 33 |
and antifungal activities | 33 |
has recently been | 33 |
the prevention of | 33 |
the design and | 33 |
solid phase synthesis | 33 |
against herpes simplex | 33 |
the site of | 33 |
to the standard | 33 |
was followed by | 33 |
is found in | 33 |
probably due to | 33 |
findings indicate that | 33 |
caused by a | 33 |
could be detected | 33 |
carried out to | 33 |
in view of | 33 |
are needed to | 33 |
concluded that the | 33 |
an example of | 33 |
to an increase | 33 |
proteins in the | 33 |
activity against gram | 33 |
we hypothesize that | 33 |
induced diabetic rats | 33 |
similar results were | 33 |
identifi cation of | 33 |
our understanding of | 33 |
the understanding of | 33 |
is a very | 33 |
as a potent | 33 |
referred to as | 33 |
were obtained in | 33 |
of bioactive compounds | 33 |
for production of | 33 |
by the addition | 33 |
quality of life | 33 |
was also observed | 33 |
antimicrobial potential of | 33 |
rest of the | 33 |
be important for | 33 |
been reported in | 33 |
both in vitro | 33 |
can be easily | 33 |
we also found | 33 |
to be responsible | 33 |
been identified as | 33 |
secondary structure of | 33 |
well known that | 32 |
significantly increased in | 32 |
in the s | 32 |
according to our | 32 |
participate in the | 32 |
order to determine | 32 |
is an essential | 32 |
prior to the | 32 |
basis for the | 32 |
amino acids are | 32 |
is very important | 32 |
we have designed | 32 |
can be detected | 32 |
was observed that | 32 |
no significant differences | 32 |
the expression level | 32 |
of some new | 32 |
secondary aliphatic amines | 32 |
fact that the | 32 |
of the other | 32 |
are the main | 32 |
of the drug | 32 |
we are now | 32 |
its effect on | 32 |
the series of | 32 |
of the primary | 32 |
were characterized by | 32 |
design of new | 32 |
not affected by | 32 |
apoptotic cell death | 32 |
order to obtain | 32 |
was comparable to | 32 |
the amplitude of | 32 |
on the expression | 32 |
may be due | 32 |
assessment of the | 32 |
with and without | 32 |
of inhibition of | 32 |
as a source | 32 |
cells were treated | 32 |
a component of | 32 |
from the rhizomes | 32 |
it may be | 32 |
respiratory syncytial virus | 32 |
followed by the | 32 |
we have synthesized | 32 |
resonance energy transfer | 32 |
tumor cell lines | 32 |
previous studies have | 32 |
plays a role | 32 |
the viability of | 32 |
have been proposed | 32 |
of the anti | 32 |
the pattern of | 32 |
but did not | 32 |
substitution of the | 32 |
resistant strains of | 32 |
a role of | 32 |
of escherichia coli | 32 |
natural and synthetic | 32 |
mechanism by which | 32 |
in the cells | 32 |
on the structure | 32 |
the dynamics of | 32 |
bind to the | 32 |
as a function | 32 |
as it is | 32 |
were evaluated for | 32 |
used in this | 32 |
was studied by | 32 |
the results suggested | 32 |
on the same | 32 |
extract of p | 31 |
been demonstrated that | 31 |
be explained by | 31 |
gaba a receptors | 31 |
vascular smooth muscle | 31 |
have been widely | 31 |
protective effects of | 31 |
the presence or | 31 |
potent than reference | 31 |
in the mannich | 31 |
of medicinal plants | 31 |
range of biological | 31 |
serum levels of | 31 |
the presence and | 31 |
primary and secondary | 31 |
molecular mass of | 31 |
human cancer cell | 31 |
may be used | 31 |
concentration in the | 31 |
and have been | 31 |
is also a | 31 |
and at the | 31 |
target for the | 31 |
are presented in | 31 |
b and c | 31 |
the pathophysiology of | 31 |
significantly higher than | 31 |
not only the | 31 |
were tested against | 31 |
expression of a | 31 |
of the b | 31 |
high level of | 31 |
lead to a | 31 |
we believe that | 31 |
have studied the | 31 |
also able to | 31 |
is required to | 31 |
ranging from to | 31 |
balb c mice | 31 |
at least two | 31 |
in a study | 31 |
was not affected | 31 |
gene expression of | 31 |
chemical synthesis of | 31 |
isolation and characterization | 31 |
seeds of psoralea | 31 |
are capable of | 31 |
terminus of the | 31 |
may be an | 31 |
the amino acids | 31 |
mannich bases and | 31 |
of antiviral activity | 31 |
was determined using | 31 |
many of these | 31 |
investigate the role | 31 |
in this regard | 31 |
of the structure | 31 |
faculty of medicine | 31 |
a library of | 31 |
of the reaction | 31 |
results demonstrated that | 31 |
is not a | 31 |
on the th | 31 |
discussion and conclusion | 31 |
world health organization | 31 |
comparison to the | 31 |
to the n | 31 |
synthesis of new | 31 |
for in vivo | 31 |
study was designed | 31 |
and could be | 31 |
expressed in a | 31 |
are important for | 31 |
oil encapsulated in | 31 |
cell cycle arrest | 31 |
evaluation of their | 31 |
native chemical ligation | 31 |
we observed a | 31 |
a loss of | 31 |
to be highly | 31 |
useful in the | 31 |
samples were taken | 31 |
they can be | 31 |
widely distributed in | 31 |
by inhibiting the | 30 |
the measurement of | 30 |
should be noted | 30 |
growth inhibition of | 30 |
are considered as | 30 |
cell growth and | 30 |
to the target | 30 |
in a recent | 30 |
by flow cytometry | 30 |
has been a | 30 |
a and a | 30 |
was obtained from | 30 |
the host cell | 30 |
measured by the | 30 |
on the contrary | 30 |
a systematic review | 30 |
of biologically active | 30 |
mouse model of | 30 |
which is an | 30 |
faculty of science | 30 |
decreased in the | 30 |
pomegranate juice consumption | 30 |
shows that the | 30 |
antioxidant activities of | 30 |
results were obtained | 30 |
in hepg cells | 30 |
and related compounds | 30 |
activated protein kinase | 30 |
presence of an | 30 |
and biological activities | 30 |
protein in the | 30 |
was analyzed by | 30 |
the characteristics of | 30 |
with the addition | 30 |
proteins have been | 30 |
with the highest | 30 |
taking into account | 30 |
identified in the | 30 |
but also the | 30 |
the secretion of | 30 |
induced oxidative stress | 30 |
mannich bases were | 30 |
vein endothelial cells | 30 |
was evaluated in | 30 |
to the production | 30 |
growth of the | 30 |
these compounds are | 30 |
was achieved by | 30 |
and increased the | 30 |
was demonstrated that | 30 |
the family of | 30 |
of silver nanoparticles | 30 |
of the product | 30 |
were performed to | 30 |
wild type and | 30 |
nuclear magnetic resonance | 30 |
it is worth | 30 |
interacts with the | 30 |
minimum inhibitory concentration | 30 |
amino group of | 30 |
can be considered | 30 |
antitumor activity of | 30 |
elevated levels of | 30 |
among the most | 30 |
conflict of interest | 30 |
value of the | 30 |
size exclusion chromatography | 30 |
gene expression and | 30 |
recent advances in | 30 |
of cancer cells | 30 |
active than the | 30 |
influenced by the | 30 |
that these compounds | 30 |
to establish the | 30 |
of naturally occurring | 30 |
also found that | 30 |
mechanisms of the | 30 |
known as the | 30 |
in the protein | 30 |
of the world | 29 |
involved in this | 29 |
chemical composition of | 29 |
of the effect | 29 |
of these enzymes | 29 |
has been described | 29 |
increased expression of | 29 |
synthesized and evaluated | 29 |
in the hippocampal | 29 |
higher than in | 29 |
quality of the | 29 |
previously reported that | 29 |
in our previous | 29 |
data show that | 29 |
review of the | 29 |
the magnitude of | 29 |
and antiviral activity | 29 |
samples were collected | 29 |
only a few | 29 |
approved by the | 29 |
of the four | 29 |
were added to | 29 |
this suggests that | 29 |
to explain the | 29 |
may be related | 29 |
changes of the | 29 |
significant increase of | 29 |
the significance of | 29 |
to be important | 29 |
the assembly of | 29 |
of cells with | 29 |
the ic values | 29 |
be effective in | 29 |
of coumarin derivatives | 29 |
japan we have | 29 |
ic values in | 29 |
search for new | 29 |
optimization of the | 29 |
was accompanied by | 29 |
various types of | 29 |
zhang et al | 29 |
a model for | 29 |
the maintenance of | 29 |
to act as | 29 |
by western blotting | 29 |
is critical for | 29 |
for their ability | 29 |
on the presence | 29 |
are used to | 29 |
we will discuss | 29 |
of the parent | 29 |
free radical scavenging | 29 |
the phosphorylation of | 29 |
even in the | 29 |
binds to the | 29 |
can be achieved | 29 |
class of compounds | 29 |
and there is | 29 |
for the control | 29 |
were collected from | 29 |
of nitric oxide | 29 |
is a well | 29 |
time course of | 29 |
in the membrane | 29 |
min mg protein | 29 |
and antioxidant activities | 29 |
and activity of | 29 |
involved in a | 29 |
increased levels of | 29 |
in the united | 29 |
essential oils of | 29 |
shown in table | 29 |
is reported to | 29 |
resulted in an | 29 |
the potency of | 29 |
department of anatomy | 29 |
activated protein c | 29 |
the gene expression | 29 |
and absence of | 29 |
by binding to | 29 |
of the s | 29 |
can be a | 29 |
light on the | 29 |
a role for | 29 |
supported by a | 29 |
the emergence of | 29 |
a high degree | 29 |
the catalytic activity | 29 |
hydrolysis of the | 29 |
inactivation of the | 29 |
after h of | 29 |
cells and the | 29 |
of peptides and | 29 |
have focused on | 29 |
by inhibition of | 29 |
of lipid peroxidation | 29 |
in the aminomethyl | 29 |
we will present | 29 |
of the effects | 29 |
is possible that | 28 |
are likely to | 28 |
in line with | 28 |
disruption of the | 28 |
limited number of | 28 |
all of them | 28 |
of human rhinovirus | 28 |
the comparison of | 28 |
cytotoxic effects of | 28 |
in the food | 28 |
a small number | 28 |
for the formation | 28 |
this effect was | 28 |
bacteria and fungi | 28 |
to prevent the | 28 |
the conformation of | 28 |
in the body | 28 |
mesenchymal stem cells | 28 |
were evaluated in | 28 |
those in the | 28 |
by solid phase | 28 |
may have a | 28 |
and expression of | 28 |
the standard drug | 28 |
at low concentrations | 28 |
in rats with | 28 |
a recent study | 28 |
an overview of | 28 |
molecular biology and | 28 |
is not clear | 28 |
was also found | 28 |
and prevention of | 28 |
is essential to | 28 |
and with the | 28 |
in all the | 28 |
shown in fig | 28 |
well as to | 28 |
this indicates that | 28 |
a signi fi | 28 |
in the c | 28 |
for detection of | 28 |
is still a | 28 |
that could be | 28 |
that the activity | 28 |
to better understand | 28 |
crucial for the | 28 |
mitochondrial membrane potential | 28 |
was increased in | 28 |
remains to be | 28 |
compared with those | 28 |
an essential role | 28 |
investigate the effect | 28 |
the results are | 28 |
to create a | 28 |
we find that | 28 |
play a crucial | 28 |
the authors declare | 28 |
both in the | 28 |
in this respect | 28 |
the peptides were | 28 |
of pharmaceutical sciences | 28 |
use of a | 28 |
is a promising | 28 |
in clinical trials | 28 |
we report on | 28 |
been carried out | 28 |
has been investigated | 28 |
mutation in the | 28 |
molecular basis of | 28 |
means of the | 28 |
a broad range | 28 |
been identified in | 28 |
we determined the | 28 |
is a powerful | 28 |
to the discovery | 28 |
were associated with | 28 |
studies suggest that | 28 |
compounds such as | 28 |
to modulate the | 28 |
of the genes | 28 |
of the immune | 28 |
shown to inhibit | 28 |
for more than | 28 |
of the antiviral | 28 |
more effective than | 28 |
was evaluated using | 28 |
of the substrate | 28 |
is the main | 28 |
activity has been | 28 |
conformation of the | 28 |
experiments were carried | 28 |
the decrease in | 28 |
might be a | 28 |
the cell wall | 28 |
male and female | 28 |
lactic acid bacteria | 28 |
with the exception | 28 |
of mg ml | 28 |
in this paper | 28 |
mrna expression of | 28 |
of prostate cancer | 28 |
essential role in | 28 |
for inhibition of | 28 |
the exception of | 28 |
of up to | 28 |
order to study | 28 |
did not change | 28 |
was determined as | 28 |
risk factors for | 28 |
of a number | 28 |
focus on the | 28 |
and it has | 28 |
and antibacterial activity | 28 |
the state of | 28 |
decrease of the | 28 |
of the antibiotic | 28 |
their antimicrobial activity | 28 |
against oxidative stress | 28 |
examined the effect | 28 |
of plant extracts | 28 |
for min at | 28 |
cytotoxic activity of | 28 |
be an important | 28 |
the results revealed | 28 |
japan in the | 27 |
in vivo in | 27 |
in vitro study | 27 |
of the control | 27 |
are related to | 27 |
of the plasma | 27 |
be one of | 27 |
well as their | 27 |
in the search | 27 |
portion of the | 27 |
the beginning of | 27 |
exposed to the | 27 |
the assessment of | 27 |
in the left | 27 |
are one of | 27 |
previously shown that | 27 |
of this protein | 27 |
study was conducted | 27 |
is expected to | 27 |
in the activity | 27 |
compared to controls | 27 |
the creation of | 27 |
have reported that | 27 |
during the last | 27 |
the stimulation of | 27 |
huang et al | 27 |
for the prevention | 27 |
a better understanding | 27 |
influenza a virus | 27 |
terminal part of | 27 |
of the host | 27 |
riken brain science | 27 |
as a therapeutic | 27 |
relative to the | 27 |
of a peptide | 27 |
comparable to the | 27 |
highly expressed in | 27 |
with a view | 27 |
activity on the | 27 |
the origin of | 27 |
in vitro assays | 27 |
stages of the | 27 |
in human plasma | 27 |
been observed in | 27 |
extracted from the | 27 |
has been associated | 27 |
programmed cell death | 27 |
the target protein | 27 |
compared with control | 27 |
we hypothesized that | 27 |
were screened for | 27 |
of the process | 27 |
concentration of mg | 27 |
was tested in | 27 |
developed for the | 27 |
of a variety | 27 |
were identified as | 27 |
regardless of the | 27 |
a and c | 27 |
morbidity and mortality | 27 |
inhibited the growth | 27 |
and the most | 27 |
in in vitro | 27 |
tool for the | 27 |
the rats were | 27 |
to the c | 27 |
catalytic activity of | 27 |
against staphylococcus aureus | 27 |
department of biochemistry | 27 |
synthesis and antimicrobial | 27 |
the antimicrobial potential | 27 |
interfere with the | 27 |
functions as a | 27 |
male wistar rats | 27 |
over the past | 27 |
two of the | 27 |
the immune response | 27 |
compounds were evaluated | 27 |
have been obtained | 27 |
the roles of | 27 |
addition of the | 27 |
of particular interest | 27 |
had to be | 27 |
th day and | 27 |
absence of the | 27 |
and to the | 27 |
to develop new | 27 |
a view to | 27 |
to this end | 27 |
antimicrobial activity and | 27 |
in a wide | 27 |
are active against | 27 |
cells treated with | 27 |
was no significant | 27 |
the enzyme is | 27 |
bound to the | 27 |
background and aims | 27 |
the diagnosis of | 27 |
our aim was | 27 |
the molecular basis | 27 |
use in the | 27 |
colon cancer cells | 27 |
closely related to | 27 |
studies demonstrated that | 27 |
work is to | 27 |
pi k akt | 27 |
to the activity | 27 |
observed for the | 27 |
methanol extract of | 27 |
an ic of | 27 |
this may be | 27 |
cd and cd | 27 |
antiviral effects of | 27 |
with or without | 27 |
potent activity against | 26 |
evidence that the | 26 |
these peptides are | 26 |
little or no | 26 |
was characterized by | 26 |
and the resulting | 26 |
a pivotal role | 26 |
in the post | 26 |
are required to | 26 |
is widely used | 26 |
is represented by | 26 |
there are many | 26 |
these results demonstrate | 26 |
of membrane proteins | 26 |
able to bind | 26 |
investigate the effects | 26 |
the utilization of | 26 |
to a lesser | 26 |
cell lines and | 26 |
the order of | 26 |
activity of flavonoids | 26 |
the development and | 26 |
in vitro in | 26 |
as a major | 26 |
chen et al | 26 |
was performed with | 26 |
to be in | 26 |
their effects on | 26 |
the activity and | 26 |
experiments were performed | 26 |
results will be | 26 |
in all cases | 26 |
amino acid composition | 26 |
trypsin inhibitory activity | 26 |
a powerful tool | 26 |
the patients with | 26 |
synthesized by the | 26 |
has become a | 26 |
observed that the | 26 |
of the cellular | 26 |
and analysis of | 26 |
proteins that are | 26 |
tuberculosis h rv | 26 |
after oral administration | 26 |
to play an | 26 |
it is the | 26 |
should be considered | 26 |
to the synthesis | 26 |
have previously shown | 26 |
the concentrations of | 26 |
also found to | 26 |
the reaction mixture | 26 |
inflammatory activity of | 26 |
we report here | 26 |
in the structure | 26 |
well as for | 26 |
antimicrobial properties of | 26 |
performance of the | 26 |
the highest value | 26 |
of the d | 26 |
activation in the | 26 |
could be useful | 26 |
cell lines were | 26 |
to the identification | 26 |
series of mannich | 26 |
were performed using | 26 |
proteins of the | 26 |
by the russian | 26 |
as a marker | 26 |
the evolution of | 26 |
order to identify | 26 |
have been observed | 26 |
in the cns | 26 |
for h at | 26 |
was treated with | 26 |
evidence suggests that | 26 |
be present in | 26 |
to find out | 26 |
in a cell | 26 |
were measured in | 26 |
believed to be | 26 |
be a useful | 26 |
in medicinal chemistry | 26 |
that most of | 26 |
high affi nity | 26 |
could also be | 26 |
to the same | 26 |
of the e | 26 |
we decided to | 26 |
chemical modification of | 26 |
the control and | 26 |
the work was | 26 |
to investigate whether | 26 |
activity in vivo | 26 |
in the host | 26 |
in both the | 26 |
the oxidative stress | 26 |
that they are | 26 |
mg kg b | 26 |
processes such as | 26 |
quantitative analysis of | 26 |
a long time | 26 |
to address the | 26 |
effect of a | 26 |
antioxidant activity was | 26 |
fold higher than | 26 |
and the effect | 26 |
was increased by | 26 |
isothermal titration calorimetry | 26 |
the cerebral cortex | 26 |
was more potent | 26 |
gaba a receptor | 26 |
action of these | 26 |
of some of | 26 |
were studied in | 26 |
of the known | 26 |
as an important | 26 |
the complexity of | 26 |
the reference drug | 26 |
after treatment with | 26 |
of the catalytic | 26 |
been proposed to | 26 |
dynamics of the | 26 |
was monitored by | 26 |
in the cytoplasm | 26 |
our data suggest | 26 |
of influenza virus | 26 |
be concluded that | 26 |
their role in | 26 |
acids in the | 26 |
selective inhibitors of | 26 |
of neurons in | 26 |
to the corresponding | 26 |
modes of action | 25 |
are necessary to | 25 |
has been implicated | 25 |
for a long | 25 |
also been reported | 25 |
the treatment with | 25 |
double mannich bases | 25 |
of this plant | 25 |
of the novel | 25 |
is the only | 25 |
of the recombinant | 25 |
open reading frame | 25 |
the difference in | 25 |
in vitro evaluation | 25 |
has shown that | 25 |
and does not | 25 |
results from the | 25 |
and the presence | 25 |
decline on day | 25 |
after days of | 25 |
a highly conserved | 25 |
activity of this | 25 |
are consistent with | 25 |
by in vitro | 25 |
and has a | 25 |
a significant reduction | 25 |
to be present | 25 |
a comparison of | 25 |
impact of the | 25 |
the affinity of | 25 |
vitro activity of | 25 |
binding properties of | 25 |
the human body | 25 |
mainly due to | 25 |
a new method | 25 |
in the aromatic | 25 |
the appearance of | 25 |
addition of volatile | 25 |
blood pressure and | 25 |
the small intestine | 25 |
is induced by | 25 |
in this research | 25 |
these data indicate | 25 |
the overexpression of | 25 |
their biological activity | 25 |
content in the | 25 |
involved in cell | 25 |
of the initial | 25 |
to each other | 25 |
showed a significant | 25 |
methods for the | 25 |
the prevalence of | 25 |
release of the | 25 |
goal of this | 25 |
were reported to | 25 |
formation in the | 25 |
starting point for | 25 |
different stages of | 25 |
in the cerebellum | 25 |
endothelial growth factor | 25 |
amino acids with | 25 |
the establishment of | 25 |
upper respiratory tract | 25 |
each of these | 25 |
be carried out | 25 |
identification of a | 25 |
has been known | 25 |
biologically active peptides | 25 |
function in the | 25 |
study revealed that | 25 |
are necessary for | 25 |
concentrations in the | 25 |
the migration of | 25 |
activities of some | 25 |
the cause of | 25 |
in hek cells | 25 |
may serve as | 25 |
in a rat | 25 |
resulting from the | 25 |
were grown in | 25 |
during the course | 25 |
peptides and their | 25 |
is also known | 25 |
are reported to | 25 |
the transcription factor | 25 |
properties of these | 25 |
cordyceps sinensis on | 25 |
impact on the | 25 |
the potential for | 25 |
it would be | 25 |
biological activity and | 25 |
order to improve | 25 |
introduction of the | 25 |
be expressed in | 25 |
and protein expression | 25 |
is difficult to | 25 |
we tested the | 25 |
that there are | 25 |
proteins such as | 25 |
this study the | 25 |
there have been | 25 |
the effect on | 25 |
the improvement of | 25 |
affinity for the | 25 |
peptides were synthesized | 25 |
has the potential | 25 |
as the main | 25 |
which are the | 25 |
terminal domain of | 25 |
the transport of | 25 |
derived from a | 25 |
was subjected to | 25 |
comparable to those | 25 |
the initiation of | 25 |
against candida albicans | 25 |