trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	607
the presence of	484
in order to	444
the use of	337
the effect of	316
the development of	312
the synthesis of	306
one of the	301
based on the	262
the production of	248
the formation of	216
the role of	215
in the presence	208
the effects of	207
found to be	194
was found to	193
it has been	191
in this study	187
the expression of	185
due to the	183
involved in the	180
a number of	163
on the other	162
the other hand	154
in addition to	154
the treatment of	152
analysis of the	152
a variety of	150
can be used	145
the activity of	143
of amino acids	141
a series of	139
in the present	138
the amino acid	138
of the peptide	138
structure of the	134
been shown to	127
role in the	127
of sialic acid	126
to be a	126
the present study	125
activity of the	124
the number of	120
the mechanism of	120
the aim of	119
has been shown	117
shown to be	117
the influence of	117
in patients with	116
part of the	116
amino acid residues	115
well as the	113
were found to	113
the case of	112
in the case	111
in vitro and	110
the structure of	109
of amino acid	108
used as a	108
and in vivo	107
the growth of	107
found in the	106
in this work	105
was used to	103
have shown that	103
is one of	103
the inhibition of	101
the addition of	100
changes in the	100
vitro and in	99
an important role	99
was carried out	98
of the human	98
according to the	98
the plasma membrane	97
the analysis of	97
to determine the	95
responsible for the	95
the design of	94
has been reported	94
of the most	94
the regulation of	93
such as the	93
related to the	93
is associated with	93
by means of	93
the activation of	92
and characterization of	91
to study the	91
in which the	90
the binding of	90
in terms of	90
as a result	90
the absence of	90
to investigate the	90
important role in	89
of sialic acids	88
for the treatment	88
the interaction of	87
the amount of	87
compared to the	86
the ability of	86
the results of	86
this work was	86
amino acids and	86
used for the	85
studies on the	85
to that of	84
of the n	84
it was found	83
will be presented	83
the application of	82
associated with the	82
in contrast to	82
and in the	82
the importance of	82
some of the	81
present in the	81
in combination with	80
in the brain	80
amino acids in	79
laser desorption ionization	79
the basis of	78
isolated from the	78
showed that the	78
to be the	78
for the synthesis	78
is involved in	78
wide range of	77
the release of	77
of this study	77
the action of	77
expression of the	77
of the enzyme	76
has also been	75
phase peptide synthesis	75
was shown to	75
was supported by	75
of the protein	74
for the production	74
will be discussed	74
properties of the	74
of the cell	74
the rate of	73
there is a	73
a wide range	73
the identification of	73
seems to be	73
are involved in	73
the level of	73
this study was	73
nature of the	72
results suggest that	72
effect on the	72
was found that	72
effect of the	72
the ability to	71
the preparation of	71
be used as	71
synthesis of the	71
be used to	71
found that the	71
that of the	71
signi fi cantly	71
with respect to	70
most of the	70
of neu gc	69
their ability to	69
amino acid sequence	69
have been reported	69
is based on	69
depending on the	68
study was to	68
a range of	68
increase in the	68
the surface of	68
used in the	68
be involved in	67
has been used	67
the concentration of	67
of the two	67
for the development	67
on the basis	66
mechanism of action	66
were used to	66
synthesis of a	65
biological activity of	65
the fact that	65
because of the	64
an increase in	64
resulted in a	64
sialic acid binding	63
assisted laser desorption	63
derived from the	63
which can be	63
to increase the	62
a and b	62
central nervous system	62
large number of	62
which is a	62
appears to be	61
of the amino	61
the nature of	61
due to their	60
were carried out	60
characterization of the	60
a role in	60
to improve the	60
of pomegranate juice	60
the levels of	60
is an important	59
we found that	59
well as in	59
that can be	59
of the peptides	59
revealed that the	59
contribute to the	58
in the absence	58
at the c	58
aim of this	58
are able to	58
been reported to	58
the sialic acid	58
be used for	57
of the c	57
signi fi cant	57
due to its	57
have been used	57
is known to	57
role of the	57
of punica granatum	57
development of a	57
the immune system	57
it was shown	57
is required for	57
the majority of	56
the cell membrane	56
in the liver	56
the process of	56
on the surface	56
it is a	56
a set of	56
a combination of	56
been used to	56
in relation to	55
function of the	55
similar to that	55
the control of	55
have been shown	55
were able to	55
in the human	54
the most important	54
acetylated sialic acids	54
the cell surface	54
of action of	54
of a new	54
has been found	54
work was supported	54
has been developed	54
a family of	54
end of the	53
in the treatment	53
use of the	53
of these peptides	53
a large number	53
acids in the	53
activation of the	53
m g ml	53
results indicate that	53
carried out in	53
suggest that the	53
shown that the	52
of a novel	52
the stability of	52
is the most	52
presence of the	52
as compared to	52
the study of	52
in response to	52
play an important	51
method for the	51
in the same	51
it is possible	51
we have developed	51
as shown in	51
a mixture of	51
the pathogenesis of	51
results showed that	50
the function of	50
solid phase peptide	50
tumor necrosis factor	50
members of the	50
the possibility of	50
formation of a	50
known to be	50
breast cancer cells	50
the end of	50
is responsible for	50
cancer cell lines	50
have been developed	50
be used in	50
the generation of	50
it is not	50
by mass spectrometry	50
the amino acids	49
the determination of	49
different types of	49
the fi rst	49
the interaction between	49
is able to	49
binding to the	49
dha and epa	49
been found to	49
can also be	48
the biological activity	48
department of chemical	48
at the same	48
located in the	48
stability of the	48
in the development	48
the detection of	48
the tca cycle	48
the most common	48
study of the	47
at the n	47
was used as	47
amino acids are	46
is present in	46
the in vitro	46
the lack of	46
is characterized by	46
fatty acids in	46
have been identified	46
in the rat	46
the present work	46
composition of the	46
observed in the	45
were shown to	45
to evaluate the	45
have also been	45
is mediated by	45
the side chain	45
the existence of	45
the range of	45
it can be	45
the conversion of	45
have been found	45
in case of	45
the active site	45
was shown that	45
the incorporation of	44
the central nervous	44
of influenza virus	44
presence of a	44
in the regulation	44
pomegranate fruit extract	44
the course of	44
the introduction of	44
the sequence of	44
appear to be	44
of the major	44
as a model	44
a group of	44
attached to the	44
formation of the	44
results show that	44
has not been	44
added to the	43
to be involved	43
are associated with	43
demonstrated that the	43
peptides and proteins	43
sequence of the	43
the synthesis and	43
applied to the	42
depends on the	42
than that of	42
we conclude that	42
are responsible for	42
sialic acids in	42
are found in	42
in the last	42
we report the	42
based on a	42
the combination of	42
region of the	42
determination of the	42
understanding of the	42
oral administration of	42
characterization of a	42
at room temperature	42
compared with the	42
influenza a virus	41
antimicrobial activity of	41
in the formation	41
amino acid sequences	41
focused on the	41
polyunsaturated fatty acids	41
led to the	41
fatty acids and	41
required for the	41
together with the	41
of these compounds	41
are known to	41
member of the	40
the accumulation of	40
to the cell	40
acid in the	40
proved to be	40
and in vitro	40
the biosynthesis of	40
were synthesized by	40
the degree of	40
characterized by a	40
reactive oxygen species	40
sialic acid glycan	40
has been demonstrated	40
a result of	40
some of these	40
the extent of	40
shown in fig	40
leads to the	39
to reduce the	39
addition to the	39
of chemical engineering	39
the result of	39
show that the	39
indicate that the	39
there is no	39
comparison of the	39
we have shown	39
were used for	39
also known as	39
the distribution of	39
and can be	39
studies showed that	39
has been described	39
the context of	39
was found in	39
on the growth	39
ionization mass spectrometry	38
dependent on the	38
in the central	38
evaluation of the	38
to identify the	38
activity in the	38
punica granatum l	38
in recent years	38
is essential for	38
in escherichia coli	38
can be found	38
we investigated the	38
of cancer cells	38
one or more	38
for the preparation	38
is used to	38
effects of the	38
in the range	38
pomegranate seed oil	38
the method was	38
in the literature	38
and function of	38
which is the	37
structural characterization of	37
been shown that	37
in presence of	37
of gallic acid	37
structure and function	37
wide variety of	37
of a protein	37
desorption ionization mass	37
are present in	37
the loss of	37
in the context	37
a decrease in	36
cellular uptake of	36
hairy root cultures	36
to inhibit the	36
carried out by	36
inhibitory activity of	36
to interact with	36
the characterization of	36
was applied to	36
the relationship between	36
these results suggest	36
a systematic review	36
could be used	36
that it is	36
sialic acid in	36
obtained from the	36
the discovery of	36
were used as	36
of the target	36
of the proteins	36
of acetic acid	36
play a role	36
of patients with	36
for the design	36
when compared to	36
of the total	36
of nucleic acid	36
the performance of	35
studies of the	35
to understand the	35
this study we	35
in the process	35
in the plasma	35
likely to be	35
the metabolism of	35
herpes simplex virus	35
structure of a	35
the potential of	35
of this work	35
with the use	35
reported to be	35
of the different	35
residues in the	35
at the end	35
was added to	35
associated with a	35
each of the	35
as a consequence	35
supported by the	35
in this context	35
inhibition of the	35
in the pathogenesis	35
regulation of the	35
is used as	35
tandem mass spectrometry	35
development of new	35
the uptake of	35
the purpose of	34
high levels of	34
resulting in a	34
the composition of	34
the changes in	34
is a major	34
because of their	34
be due to	34
seem to be	34
a study of	34
was used for	34
of the present	34
to the synthesis	34
corresponding to the	34
this is the	34
amino acids were	34
found to have	34
use of a	34
be related to	34
effects on the	34
components of the	34
of aminopeptidase n	34
the involvement of	33
referred to as	33
solid phase synthesis	33
results in the	33
attributed to the	33
change in the	33
chain fatty acids	33
we are currently	33
is that the	33
a wide variety	33
performance liquid chromatography	33
in comparison with	33
development of the	33
the induction of	33
plays an important	33
by using the	33
as described in	33
crystal structure of	33
in the first	33
in comparison to	33
is composed of	33
in this case	33
of antimicrobial peptides	33
molecular mass of	33
influence of the	33
of fatty acids	33
antibacterial activity of	33
in this paper	33
was observed in	33
of escherichia coli	33
has to be	33
due to a	33
acid glycan binding	33
identification of the	33
amino acid composition	33
the increase in	33
the hydrolysis of	32
of the first	32
broad spectrum of	32
be responsible for	32
the potential to	32
surface of the	32
is related to	32
has been proposed	32
differences in the	32
to be used	32
peptides derived from	32
is important for	32
many of the	32
all of the	32
produced by the	32
and it is	32
essential for the	32
the results obtained	32
studies have shown	31
a sialic acid	31
the immune response	31
and amino acid	31
a review of	31
and on the	31
of lactic acid	31
levels of the	31
in the synthesis	31
of the reaction	31
to characterize the	31
for production of	31
relationship between the	31
the reduction of	31
some of them	31
leading to the	31
the type of	31
insight into the	31
the impact of	31
sialic acid is	31
investigation of the	31
the structure and	31
with the aim	31
for this purpose	31
contributes to the	31
for use in	31
used as an	31
to have a	31
information on the	31
identifi cation of	31
the most potent	31
of the three	31
been associated with	31
amino acid residue	31
we have synthesized	31
but not in	31
review of the	31
influenza virus infection	31
the evaluation of	31
the same time	31
are the most	30
the degradation of	30
the ratio of	30
be found in	30
is a potent	30
the secondary structure	30
acids and bases	30
mode of action	30
the efficiency of	30
importance of the	30
production of the	30
the onset of	30
for h at	30
identification of a	30
for analysis of	30
of the main	30
was performed by	30
and has been	30
interact with the	30
mechanisms of action	30
to be an	30
cancer cells and	30
in animal models	30
pomegranate juice consumption	30
it is also	30
for treatment of	30
be attributed to	30
epa and dha	30
was isolated from	30
to form a	30
of the same	30
and biological activity	30
the need for	30
in vivo and	30
have developed a	30
were found in	30
by the presence	30
to assess the	30
are characterized by	30
a class of	30
to those of	30
believed to be	29
inhibitory effect on	29
is important to	29
in some cases	29
is thought to	29
the ph of	29
inhibitory effect of	29
appeared to be	29
belonging to the	29
a source of	29
in a dose	29
have not been	29
were identified by	29
proteins involved in	29
has been suggested	29
is believed to	29
regions of the	29
aim of the	29
results in a	29
designed and synthesized	29
of the disease	29
an in vitro	29
it is known	29
with that of	29
between the two	29
c and c	29
structures of the	29
results of the	29
as a new	29
the form of	29
the gastrointestinal tract	29
in cancer cells	29
considered to be	29
removal of the	29
position of the	29
on the use	29
serum levels of	29
the in vivo	29
thought to be	29
a member of	29
of which are	29
gene expression in	29
to play a	29
no effect on	29
the results showed	29
was determined by	29
the proliferation of	29
the peptides were	28
it may be	28
in the form	28
this study is	28
serve as a	28
is the first	28
diseases such as	28
can be achieved	28
the mode of	28
a signi fi	28
a key role	28
of tannic acid	28
we have investigated	28
in vivo studies	28
in the control	28
parts of the	28
in our laboratory	28
interaction with the	28
is possible to	28
of the viral	28
of the host	28
linked sialic acids	28
in hairy roots	28
is found in	28
well as a	28
caused by the	28
be associated with	28
is expressed in	28
of nucleic acids	28
we have studied	28
new class of	28
state of the	28
of this enzyme	28
sialic acids and	28
those of the	28
by the addition	28
shown in figure	28
is known about	28
indicated that the	28
distribution of the	28
an inhibitor of	28
of glutamic acid	28
of ellagic acid	27
in the production	27
chemical synthesis of	27
that have been	27
with a high	27
be considered as	27
were obtained from	27
been used for	27
could be a	27
a part of	27
content of the	27
with regard to	27
expressed in the	27
it is important	27
high degree of	27
suggested that the	27
native chemical ligation	27
to develop a	27
mechanism of the	27
knowledge of the	27
a total of	27
molecular weight of	27
similar to the	27
influence on the	27
as a potential	27
structural analysis of	27
to be more	27
for the analysis	27
similar to those	27
which could be	27
in the field	27
low molecular weight	27
were isolated from	27
surface plasmon resonance	27
of proteins and	27
in the cell	27
been identified as	27
large amounts of	27
is due to	27
have to be	27
side chain of	27
detected in the	27
of the molecule	27
for the detection	27
we have recently	27
lead to the	27
is caused by	26
this type of	26
in the following	26
linked sialic acid	26
and gallic acid	26
were prepared by	26
prostate cancer cells	26
of small molecules	26
to the development	26
the interactions between	26
are based on	26
resulted in the	26
sialic acids are	26
the first time	26
step in the	26
was confirmed by	26
cells in the	26
and development of	26
data suggest that	26
sialic acid residues	26
linked to the	26
high affi nity	26
to elucidate the	26
major role in	26
was able to	26
was obtained by	26
the conformation of	26
gallic acid and	26
dicaffeoylquinic acid and	26
the concentrations of	26
and that the	26
antimicrobial activity against	26
were analyzed by	26
have been studied	26
were observed in	26
data on the	26
is similar to	26
by using a	26
site of the	26
in aqueous solution	26
a broad spectrum	26
interactions between the	26
on the cell	26
has been studied	26
the control group	26
because of its	26
this work we	26
we have used	26
are shown in	26
activity of a	26
based on these	26
by solid phase	25
the problem of	25
we show that	25
important for the	25
to the n	25
characterized by the	25
in the cytoplasm	25
followed by the	25
present study was	25
crucial for the	25
may contribute to	25
may be a	25
contrast to the	25
have investigated the	25
form of the	25
free sialic acid	25
may lead to	25
amino acids with	25
in the past	25
the separation of	25
the most active	25
in cancer therapy	25
is a highly	25
of a peptide	25
of a single	25
and have been	25
we describe the	25
peptides were synthesized	25
it is well	25
led to a	25
of peptides and	25
were obtained by	25
be able to	25
shown in table	25
the size of	25
we have also	25
of the plasma	25
as an alternative	25
neu gc in	25
a method for	25
has been recently	25
in the nucleus	25
in a mouse	25
in mammalian cells	25
could be detected	25
phase synthesis of	25
its ability to	25
control of the	25
a consequence of	25
key role in	25
consistent with the	24
focus on the	24
and of the	24
acts as a	24
has been identified	24
genes involved in	24
higher than that	24
terminus of the	24
a crucial role	24
we examined the	24
in the design	24
is used in	24
quantitative analysis of	24
the incidence of	24
potent and selective	24
could not be	24
is known that	24
of the b	24
they can be	24
the binding site	24
which may be	24
difference in the	24
the functions of	24
and production of	24
have been published	24
tof mass spectrometry	24
size of the	24
belongs to the	24
in the food	24
of gene expression	24
a new method	24
enzymes involved in	24
part of a	24
little is known	24
cells in vitro	24
characteristics of the	24
the field of	24
the most abundant	24
of the brain	24
have been isolated	24
to obtain a	24
were synthesized and	24
of the immune	24
the position of	24
expressed in e	24
of the resulting	24
in the course	24
of the native	24
component of the	24
a reduction in	24
the risk of	24
been suggested that	24
background and aims	24
in the mouse	24
of the virus	24
the antibacterial activity	23
in the diet	23
we have identified	23
antioxidant activity of	23
to enhance the	23
have been synthesized	23
active site of	23
suggesting that the	23
aspects of the	23
a new class	23
acid sequence of	23
mediated by the	23
were performed in	23
interest in the	23
glutamic acid residues	23
is well known	23
is likely to	23
the properties of	23
the prediction of	23
is a key	23
these results indicate	23
vivo and in	23
inhibitors of the	23
in the blood	23
caused by a	23
domain of the	23
of these enzymes	23
serves as a	23
a major role	23
cleavage of the	23
to analyze the	23
we have designed	23
reported that the	23
lactic acid bacteria	23
were detected in	23
the value of	23
of nitric oxide	23
was studied in	23
modification of the	23
is not a	23
the influenza virus	23
is a very	23
molecular dynamics simulations	23
ph of the	23
of the four	23
are used in	23
in the active	23
at least in	23
of the above	23
secondary structure of	23
the golgi apparatus	23
we present the	23
it is the	23
we have previously	23
ability of the	23
the first step	23
sialic acid and	23
a mouse model	23
concentration of the	23
of rhus chinensis	23
cancer cells in	23
residues of the	23
red blood cells	23
in vitro studies	23
optimization of the	23
results from the	23
for the first	23
here we report	23
of at least	23
of the compounds	23
reduction in the	23
were tested for	23
positive and gram	23
at least two	23
was studied by	23
the removal of	23
suggests that the	23
be applied to	23
can be applied	23
unnatural amino acids	23
of neu ac	23
peptides and their	23
of secondary metabolites	23
analysis of protein	23
of more than	22
used as the	22
of the membrane	22
to test the	22
plays a role	22
resistant staphylococcus aureus	22
phenolic acid constituents	22
development of novel	22
are required to	22
of the new	22
increase of the	22
of vitamin a	22
to obtain the	22
as a receptor	22
amino acid transport	22
of the study	22
used to study	22
of this protein	22
of pomegranate fruit	22
a comparison of	22
the results suggested	22
in prostate cancer	22
cells of the	22
of the natural	22
tested for their	22
as it is	22
rational design of	22
and its application	22
did not affect	22
as part of	22
for binding to	22
the significance of	22
antiviral activity of	22
in our previous	22
a function of	22
of dha and	22
chemical structure of	22
was reported to	22
a high degree	22
to the formation	22
the availability of	22
the last years	22
this is a	22
basis of the	22
for detection of	22
in the study	22
followed by a	22
and mass spectrometry	22
human breast cancer	22
academy of sciences	22
interaction between the	22
also been used	22
to bind to	22
biologically active peptides	22
our results suggest	22
action of the	22
the construction of	22
ms analysis of	22
we were able	22
the activities of	22
the brain and	22
a concentration of	22
were used in	22
and may be	22
by use of	22
protein kinase c	22
the reaction of	22
an example of	22
that has been	22
is not known	22
we present a	22
and for the	22
described in the	22
the cells were	22
been found in	21
structural and functional	21
leads to a	21
concentration in the	21
length of the	21
an overview of	21
of the metabolic	21
inhibitor of aminopeptidase	21
encoded by the	21
as one of	21
there is an	21
release of the	21
conformation of the	21
located at the	21
the quality of	21
are used to	21
which in turn	21
group of the	21
be achieved by	21
b and c	21
potent inhibitors of	21
the administration of	21
of galla chinensis	21
mutations in the	21
of influenza a	21
decrease in the	21
in this regard	21
these peptides are	21
affi nity for	21
the progression of	21
under conditions of	21
in the intestine	21
of hairy roots	21
presence of an	21
close to the	21
were determined by	21
was to investigate	21
crucial role in	21
in the early	21
is necessary to	21
the inhibitory activity	21
in a number	21
a target for	21
human immunodeficiency virus	21
as a source	21
the present paper	21
mass spectrometry and	21
the time of	21
disruption of the	21
specificity of the	21
for the study	21
the specificity of	21
allowed us to	21
critical role in	21
results indicated that	21
of the dna	21
in all the	21
in the c	21
be the most	21
of the s	21
peptides have been	21
the sensitivity of	21
is crucial for	21
hydrolysis of the	21
a critical role	21
binding of the	21
two types of	21
the attachment of	21
the interaction with	21
of the p	21
as a control	21
the prevention of	21
are required for	21
been applied to	21
according to their	21
is a novel	21
with amino acids	21
the length of	21
the increase of	21
will be used	21
of the cells	21
addition of the	21
the peptide backbone	21
cell penetrating peptides	21
the host cell	21
in the n	21
inhibit the growth	21
there was a	21
infl uence of	21
the appearance of	21
were characterized by	20
was investigated in	20
in the binding	20
and is a	20
the delivery of	20
have been described	20
department of biology	20
binding properties of	20
nitric oxide synthase	20
for their ability	20
small amounts of	20
point of view	20
can serve as	20
the most effective	20
of the active	20
the mechanisms of	20
total synthesis of	20
of the structure	20
have been proposed	20
by the use	20
elucidation of the	20
that may be	20
neu gc is	20
were treated with	20
amino acid side	20
about of the	20
health and disease	20
the target protein	20
the cellular uptake	20
design of a	20
in the sequence	20
and expression of	20
basis for the	20
of a large	20
been used as	20
the fatty acid	20
the solid phase	20
reduction of the	20
wang et al	20
acid has been	20
terminal part of	20
of the effects	20
and analysis of	20
roles in the	20
of cells with	20
the results show	20
has been applied	20
necessary for the	20
to predict the	20
of a series	20
results of this	20
be divided into	20
effects of a	20
expression of a	20
lee et al	20
other amino acids	20
systematic review and	20
amino acids to	20
of the binding	20
methods for the	20
and treatment of	20
with sialic acid	20
of the corresponding	20
is possible that	20
a complete reduction	20
obtained in the	20
may be used	20
cell growth and	20
in the second	20
level of the	20
indicates that the	20
the selection of	20
of the cellular	20
was detected in	20
blood pressure and	20
have studied the	20
the design and	20
been identified in	20
in breast cancer	20
study on the	20
in another study	20
low levels of	20
acetylation of sialic	20
glutamic acid is	20
needs to be	20
of proteins in	20
the small intestine	20
a period of	20
we have found	20
a lack of	20
method was used	20
in the membrane	20
by click chemistry	20
the serum levels	20
of the receptor	20
can be considered	20
kg body weight	20
mouse model of	20
which has been	20
was associated with	20
of these proteins	20
carried out on	19
it should be	19
application of the	19
the sialic acids	19
significant increase in	19
an alternative to	19
antibacterial and antifungal	19
and synthesis of	19
and sialic acid	19
of protein synthesis	19
that there is	19
sialic acid glycans	19
in spite of	19
science and technology	19
in the peptide	19
may also be	19
the consumption of	19
the spike protein	19
respect to the	19
carried out using	19
the frequency of	19
work was to	19
of all the	19
that they are	19
to the c	19
a highly conserved	19
is in the	19
broad range of	19
of biologically active	19
in sialic acid	19
shown to have	19
is also a	19
and the other	19
was performed in	19
acid is a	19
essential amino acid	19
and as a	19
proteins in the	19
vascular endothelial growth	19
aim is to	19
involved in cell	19
the structures of	19
of the gene	19
is dependent on	19
order to investigate	19
of the gm	19
protein in the	19
the nervous system	19
a lot of	19
to act as	19
proteins have been	19
liu et al	19
only in the	19
nuclear magnetic resonance	19
in pr virus	19
was performed using	19
of the complex	19
as a novel	19
the assessment of	19
and has a	19
purification and characterization	19
of recombinant proteins	19
relies on the	19
at a concentration	19
potent inhibitor of	19
the antiviral activity	19
it is necessary	19
orientation of the	19
we will present	19
side chains of	19
amino acid metabolism	19
been used in	19
correlation between the	19
is necessary for	19
can be easily	19
are the main	19
natural amino acids	19
endothelial growth factor	19
the evolution of	19
suitable for the	19
to examine the	19
were incubated with	19
molecular basis of	19
that pomegranate juice	19
the concept of	19
as in the	19
the investigation of	19
we studied the	19
early stages of	19
linear and cyclic	19
order to study	19
the toxicity of	19
in the stomach	19
isolated from pomegranate	19
of the genus	19
free amino acids	19
the content of	19
influenced by the	19
this work is	19
one of these	19
closely related to	19
belong to the	19
in a wide	19
of the non	19
in the body	19
animal models of	19
open reading frame	19
pomegranate juice and	19
order to determine	19
and to the	19
the modulation of	19
conclude that the	19
binding sites in	19
synthesized by the	19
of these two	19
the isolation of	18
is an essential	18
any of the	18
the enzyme was	18
binds to the	18
metabolism in the	18
types of cancer	18
negative ion mode	18
levels in the	18
and it was	18
a role for	18
isolation and characterization	18
were performed on	18
department of chemistry	18
of the rat	18
proteins and peptides	18
not yet been	18
of the role	18
interaction of the	18
there are two	18
and the resulting	18
and identification of	18
review and meta	18
the transfer of	18
positive and negative	18
experiments were performed	18
is a common	18
functional analysis of	18
evidence suggests that	18
the utilization of	18
of the a	18
been reported that	18
for synthesis of	18
amino group of	18
on the presence	18
as inhibitors of	18
is used for	18
to explore the	18
are listed in	18
of phenolic acids	18
the peptide chain	18
plasma amino acid	18
of gum arabic	18
used to determine	18
during the last	18
with the same	18
natural and synthetic	18
bind to the	18
may play a	18
a glutamic acid	18
in most cases	18
acute respiratory distress	18
as a function	18
of lipid a	18
fatty acids on	18
with amino acid	18
been reported in	18
cell lung cancer	18
its effect on	18
can lead to	18
can be detected	18
by increasing the	18
an attempt to	18
effect of pomegranate	18
have been made	18
there was no	18
bound to the	18
a molecular mass	18
the recognition of	18
in the future	18
is not the	18
case of the	18
conformational analysis of	18
by addition of	18
and evaluation of	18
are summarized in	18
indicating that the	18
the goal of	18
as determined by	18
have been characterized	18
was investigated by	18
the last decade	18
our understanding of	18
resulting in the	18
the understanding of	18
data indicate that	18
synthesis and biological	18
mechanism by which	18
to determine whether	18
mass spectrometric analysis	18
in a single	18
depend on the	18
results suggested that	18
information about the	18
the growth and	18
acid residues in	18
many of these	18
used to treat	18
of the tca	18
are used as	18
these compounds are	18
chinese hamster ovary	18
various types of	18
in this review	18
to the control	18
results will be	18
at g l	18
analysis of a	18
may be useful	18
to optimize the	18
of the initial	18
but it is	18
affected by the	18
of the other	18
differences between the	18
the efficacy of	18
with and without	18
more than of	18
bovine serum albumin	18
of the synthesis	18
a component of	18
ic values of	18
relation to the	18
proven to be	18
the innate immune	18
fatty acid composition	18
by binding to	18
we have been	18
before and after	18
be useful in	18
acids can be	18
of the substrate	18
activity has been	18
in a variety	18
respiratory distress syndrome	18
the human genome	18
antibacterial activity against	18
and the results	18
the origin of	18
here we present	18
it was demonstrated	18
a loss of	18
of ph on	18
on the synthesis	17
be carried out	17
to be responsible	17
of in vitro	17
the occurrence of	17
have been investigated	17
the molecular mechanisms	17
of fish oil	17
acid composition of	17
the nucleic acid	17
half of the	17
efficiency of the	17
mass spectrometry for	17
can be a	17
in the immune	17
effect of different	17
be noted that	17
lactic acid production	17
studies were performed	17
antiviral activity against	17
resulting from the	17
result of the	17
enzyme in the	17
pr virus infection	17
the transport of	17
inactivation of the	17
there has been	17
in the current	17
the cell cycle	17
cell proliferation and	17
the antioxidant activity	17
for determination of	17
plasma membrane of	17
which have been	17
been developed for	17
analogues of the	17
was achieved by	17
gene expression and	17
can act as	17
sialic acid on	17
course of the	17
and structure of	17
limited number of	17
biological evaluation of	17
this article is	17
acids and their	17
the sum of	17
be explained by	17
were subjected to	17
mutation in the	17
at the time	17
value of the	17
we showed that	17
faculty of science	17
chlorogenic acid and	17
by up to	17
did not show	17
of the sialic	17
at least one	17
the secretion of	17
with an ic	17
the usefulness of	17
the cell wall	17
secreted phospholipase a	17
shows that the	17
receptors in the	17
product of the	17
of fatty acid	17
out of the	17
on the production	17
may not be	17
of a variety	17
critically ill patients	17
to clarify the	17
is determined by	17
also able to	17
for the formation	17
fraction of the	17
by nmr spectroscopy	17
the roles of	17
amino acids from	17
proteins that are	17
of science and	17
quality of life	17
expressed in a	17
of the influenza	17
of the process	17
in agreement with	17
comparison with the	17
primary and secondary	17
takes place in	17
had no effect	17
sialic acids is	17
a decrease of	17
the possibility to	17
the molecular basis	17
the search for	17
technical university of	17
results were obtained	17
well as their	17
it was also	17
we decided to	17
the initiation of	17
evolution of the	17
in rat plasma	17
the wild type	17
is carried out	17
ability to inhibit	17
occurs in the	17
and so on	17
a prerequisite for	17
a significant increase	17
of phenolic compounds	17
in the cytosol	17
higher than the	17
and the corresponding	17
to the analysis	17
human serum albumin	17
the chemical structure	17
modifi cation of	17
the results were	17
methods have been	17
functions of the	17
to sialic acid	17
acute lung injury	17
under the control	17
of sodium bicarbonate	17
the current study	17
bacteria and fungi	17
on the structure	17
aim of our	17
that in the	17
not able to	17
important in the	17
to interfere with	17
and the role	17
in the reaction	17
sialic acids as	17
of this peptide	17
of acids and	17
the assembly of	17
the interactions of	17
induction of apoptosis	17
analysis of n	17
this suggests that	17
the absorption of	17
for min at	17
programmed cell death	17
in health and	17
the yield of	17
and related compounds	17
and mg kg	17
an amino acid	17
and the presence	16
interactions with the	16
the endoplasmic reticulum	16
tool for the	16
and properties of	16
of the pro	16
able to inhibit	16
as an important	16
unsaturated fatty acids	16
the crystal structure	16
high molecular weight	16
escherichia coli k	16
activity of these	16
to control the	16
peptides can be	16
as a substrate	16
have revealed that	16
are resistant to	16
by measuring the	16
the results suggest	16
carried out to	16
the side chains	16
and fatty acid	16
are essential for	16
use in the	16
for the identification	16
the phenolic acid	16
and biological evaluation	16
goal of this	16
stages of the	16
production of recombinant	16
than in the	16
of chemical and	16
was demonstrated that	16
been found that	16
the university of	16
been carried out	16
incorporated into the	16
and inhibition of	16
of carbohydrates and	16
and its derivatives	16
have demonstrated that	16
synthesis of peptides	16
the inhibitory effect	16
of natural products	16
chronic kidney disease	16
majority of the	16
were compared with	16
on growth and	16
glutamic acid and	16
a role of	16
higher than in	16
in normal and	16
can be produced	16
listed in table	16
in tumor cells	16
the viability of	16
glycoproteins and glycolipids	16
and their derivatives	16
to monitor the	16
of cell surface	16
with the highest	16
we are now	16
sequences of the	16
at the level	16
summarized in table	16
and some of	16
the severity of	16
of chlorogenic acid	16
amino acids that	16
could also be	16
insights into the	16
have been obtained	16
to the high	16
widely distributed in	16
are expected to	16
in cancer patients	16
sites in the	16
amino acid and	16
for the activation	16
of naturally occurring	16
tian et al	16
our results show	16
that the peptide	16
flight mass spectrometry	16
limited by the	16
we developed a	16
at physiological ph	16
the cancer cells	16
of a high	16
well as its	16
peptides in the	16
the characteristics of	16
compounds such as	16
the antimicrobial activity	16
of the lipid	16
p and p	16
the basis for	16
ranging from to	16
on solid support	16
were obtained in	16
administration of the	16
the infl uence	16
shown to inhibit	16
also play a	16
hepatitis c virus	16
a library of	16
we have isolated	16
of one or	16
is not clear	16
the elucidation of	16
analysis of carbohydrates	16
of the novel	16
terms of the	16
severe acute respiratory	16
of skeletal muscle	16
the method of	16
with those of	16
the optimization of	16
cells and tissues	16
was assessed by	16
effects of pomegranate	16
analysis revealed that	16
residue in the	16
were purchased from	16
peptide derived from	16
observed for the	16
and purification of	16
secretory phospholipase a	16
consists of a	16
with a molecular	16
biological activities of	16
application to the	16
infected mice at	16
studies revealed that	16
the hypothesis that	16
can be obtained	16
of the acid	16
associated with an	16
the authors declare	16
of prostate cancer	16
determined by the	16
purpose of this	16
and characterized by	16
they have been	16
are likely to	16
sambucus formosananakai extract	16
the oxidation of	16
to cross the	16
drug delivery systems	16
amino acids as	16
the objective of	16
in regulation of	16
study is to	16
groups of the	16
important roles in	16
immune response to	16
in all cases	16
to use the	16
and glutamic acid	16
induced by the	16
by the action	16
act as a	16
in fl ammation	16
in the host	16
coupled to the	16
of the overall	16
features of the	16
in the medium	16
and the effect	16
affi nity and	16
we believe that	16
from patients with	16
the change in	16
to the protein	16
of pr virus	16
accumulation in the	15
the kinetics of	15
terminal sialic acid	15
human prostate cancer	15
was determined as	15
expression in the	15
of glucose and	15
protective effect of	15
recent advances in	15
to each other	15
as an example	15
of the interactions	15
identified as a	15
acute respiratory syndrome	15
of the extracellular	15
play a crucial	15
correlated with the	15
with high affinity	15
concluded that the	15
see for references	15
uptake of the	15
this may be	15
and stability of	15
the order of	15
this method is	15
we designed and	15
instead of the	15
enzymatic hydrolysis of	15
in other words	15
fold higher than	15
experiments were carried	15
considered as a	15
the solid support	15
comparison to the	15
capacity of the	15
substrate specificity of	15
one of them	15
leading to a	15
preparation of the	15
the fi nal	15
the adsorption of	15
thin layer chromatography	15
fold increase in	15
the effectiveness of	15
is considered to	15
our previous study	15
in the next	15
and activation of	15
can be seen	15
the lumen of	15
be useful for	15
based on this	15
to a lesser	15
in rats fed	15
also found in	15
of protein palmitoylation	15
and prevention of	15
lumen of the	15
with pngase f	15
amino acids of	15
the intestinal mucosa	15
was higher than	15
the results are	15
target for the	15
high content of	15
in the s	15
food and drug	15
of the drug	15
acid as a	15
of some of	15
of our study	15
have found that	15
the early stages	15
maldi mass spectrometry	15
to remove the	15
ph on the	15
separation of the	15
to the human	15
of the core	15
there are several	15
are thought to	15
only a few	15
the site of	15
and release of	15
in plants and	15
vein endothelial cells	15
more than one	15
the help of	15
model of the	15
which has a	15
a potent inhibitor	15
to be able	15
approach for the	15
report the synthesis	15
to modulate the	15
their effect on	15
it has also	15
stimulation of the	15
the affinity of	15
or more of	15
is accompanied by	15
discussed in the	15
not only in	15
oxidative stress and	15
for in vivo	15
a change in	15
was the most	15
compounds have been	15
in a concentration	15
this class of	15
in any case	15
from natural sources	15
coronary heart disease	15
inhibitory activity against	15
from punica granatum	15
is the only	15
well as to	15
has led to	15
in in vitro	15
been demonstrated to	15
of reactive oxygen	15
on a solid	15
was measured by	15
study was supported	15
linked to a	15
was evaluated by	15
of the virion	15
to be associated	15
well known that	15
angiotensin converting enzyme	15
small number of	15
in this way	15
on the development	15
but not by	15
design and synthesis	15
but also the	15
ellagic acid and	15
antimicrobial properties of	15
provided by the	15
umbilical vein endothelial	15
our results indicate	15
the specifi c	15
blood mononuclear cells	15
in an attempt	15
amino acid derivatives	15
when compared with	15
of the latter	15
by inhibiting the	15
acid is an	15
is capable of	15
the percentage of	15
study the effect	15
found to inhibit	15
of a highly	15
i and ii	15
figure shows the	15
protein with a	15
with or without	15
the leaves of	15
as a tool	15
side of the	15
of arachidonic acid	15
of the enzymes	15
sole carbon source	15
to the presence	15
in situ hybridization	15
is difficult to	15
polymerase chain reaction	15
to be due	15
of the original	15
fatty acids are	15
gives rise to	15
design of new	15
the enzyme is	15
we are interested	15
are considered as	15
inhibitory effects on	15
which results in	15
the products of	15
along with the	15
to the same	15
high level of	14
in the dog	14
the improvement of	14
to the inhibition	14
their biological activity	14
of the t	14
of the growth	14
included in the	14
the diversity of	14
t and b	14
two of the	14
to the membrane	14
polyacrylamide gel electrophoresis	14
concentrations of the	14
proteomic analysis of	14
is to develop	14
degradation of the	14
difference between the	14
better understanding of	14
patients with acute	14
by circular dichroism	14
to be present	14
protein palmitoylation in	14
in amino acid	14
had to be	14
hydrophobic interaction chromatography	14
inhibitor of the	14
directly involved in	14
produced in the	14
ministry of education	14
are derived from	14
the possibility that	14
the aim to	14
amino acid analysis	14
independent of the	14
we synthesized a	14
have been determined	14
the pharmaceutical industry	14
also be used	14
as long as	14
been isolated from	14
of synthetic peptides	14
different stages of	14
was purified by	14
study we have	14
to provide the	14
compared to a	14
number of the	14
is the use	14
we observed that	14
on the solid	14
binding affi nity	14
the click chemistry	14
innate and adaptive	14
in accordance with	14
has been investigated	14
order to improve	14
sequence analysis of	14
chemical and biological	14
the seeds of	14
we designed a	14
proteins of the	14
to generate a	14
conflict of interest	14
dependence of the	14
the human body	14
of the use	14
were investigated in	14
should be noted	14
been implicated in	14
as the major	14
this enzyme is	14
on the molecular	14
details of the	14
activities of the	14
with the help	14
can be divided	14
of the fl	14
was comparable to	14
present study we	14
both in vitro	14
its application to	14
acid binding sites	14
was replaced by	14
lipid peroxidation and	14
the study was	14
delivery of sirna	14
acids and the	14
or absence of	14
the food industry	14
fatty acid metabolism	14
membrane of the	14
is a well	14
produced by streptomyces	14
is a promising	14
a limited number	14
hairy roots and	14
of a small	14
acids on the	14
fatty acid oxidation	14
a subset of	14
the lipid bilayer	14
for development of	14
for the determination	14
and excretion of	14
of the product	14
been widely used	14
on the expression	14
in the biosynthesis	14
supported by a	14
root cultures of	14
essential amino acids	14
properties of a	14
was to determine	14
extract of pomegranate	14
were expressed in	14
plasma membrane and	14
of the central	14
approach to the	14
are expressed in	14
cell adhesion molecule	14
acid content of	14
that could be	14
of which is	14
be detected in	14
has been widely	14
at the cell	14
example of a	14
of the production	14
proteins such as	14
able to induce	14
the rational design	14
of hairy root	14
has recently been	14
of the compound	14
and the most	14
little or no	14
the consequences of	14
concentrations in the	14
consists of two	14
was also found	14
amino acids into	14
taken up by	14
activity against gram	14
but also in	14
of the molecular	14
known about the	14
well as for	14
the most promising	14
work is to	14
of the presence	14
systematic review of	14
even in the	14
significant effect on	14
loss of the	14
this can be	14
of the individual	14
mass spectrometry of	14
to show that	14
consisting of a	14
the peptide was	14
of peptides with	14
potential of the	14
we want to	14
with the exception	14
and risk of	14
of the mechanism	14
factors such as	14
acid side chains	14
a reduction of	14
in complex with	14
of the small	14
acid and the	14
interfere with the	14
to mimic the	14
the inactivation of	14
derived from a	14
the development and	14
there have been	14
the enzymatic hydrolysis	14
enzymatic synthesis of	14
to the plasma	14
the results indicate	14
need to be	14
supported by grants	14
effects of different	14
conversion of the	14
of the sequence	14
treatment of the	14
and in a	14
the focus of	14
in the low	14
cd and nmr	14
of the synthesized	14
small interfering rna	14
lead to a	14
for the binding	14
into the cytoplasm	14
to the results	14
an increase of	14
has been associated	14
and the binding	14
it is now	14
amino acids by	14
the liver and	14
chen et al	14
in aqueous solutions	14
this effect was	14
pomegranate fl ower	14
was monitored by	14
of the fermentation	14
sialic acid was	14
is required to	14
protein of the	14
and neu gc	14
found in a	14
not only the	14
citric acid production	14
source of energy	14
the subject of	14
an effi cient	14
evidence that the	14
mass of kda	14
tend to be	14
to the peptide	14
this is not	14
kim et al	14
activity was observed	14
of food and	14
coupling of the	14
in the cns	14
recent studies have	14
based on their	14
production of a	13
in this presentation	13
colon cancer cells	13
acid is the	13
are interested in	13
are difficult to	13
the enzymatic activity	13
for the generation	13
similar results were	13
and amino acids	13
for sialic acid	13
be one of	13
effi cacy of	13
is the main	13
be required for	13
the intestinal tract	13
studies have been	13
as shown by	13
in vitro by	13
results demonstrated that	13
in clinical trials	13
of great interest	13
of breast cancer	13
of the products	13
and at the	13
existence of a	13
view of the	13
of organic acids	13
in many cases	13
purity of the	13
disulfi de bonds	13
and the c	13
the united states	13
the mixture was	13
to their ability	13
performed on a	13
for identification of	13
of the conjugates	13
the spinal cord	13
each of these	13
and fatty acids	13
of up to	13
in humans and	13
amino acid peptide	13
of both the	13
be regarded as	13
amino acid in	13
are consistent with	13
could be achieved	13
this kind of	13
and department of	13
of inflammatory cytokines	13
structure activity relationship	13
been proposed that	13
that the n	13
of the in	13
the mixture of	13
under these conditions	13
been proposed as	13
orders of magnitude	13
has been performed	13
of the literature	13
of monoclonal antibodies	13
response of the	13
to be very	13
to give a	13
were purified by	13
fl uorescence spectroscopy	13
and application of	13
of the key	13
also in the	13
and biosynthesis of	13
the center of	13
the venom of	13
of the mouse	13
and is the	13
department of biotechnology	13
may be involved	13
the experiments were	13
a powerful tool	13
a signifi cant	13
by a single	13
taking into account	13
very similar to	13
applications in the	13
infl uence on	13
in the laboratory	13
the complexity of	13
of them are	13
simplex virus type	13
as low as	13
in the serum	13
in the concentration	13
is critical for	13
to be related	13
of acid ceramidase	13
innate immune system	13
a small number	13
intrinsically disordered proteins	13
give rise to	13
leukotriene a hydrolase	13
mass spectrometry analysis	13
functions as a	13
first step in	13
ic value of	13
tumor cell lines	13
peptide synthesis in	13
up to of	13
a model for	13
it was reported	13
the need to	13
introduction of the	13
acylation of the	13
of the h	13
were obtained with	13
order to test	13
from aspergillus niger	13
order to identify	13
the measurement of	13
was due to	13
a very high	13
findings suggest that	13
of this approach	13
cell lines and	13
in a way	13
a substrate for	13
integrity of the	13
was prepared by	13
compounds in the	13
is an attractive	13
and will be	13
implicated in the	13
renal tubular acidosis	13
to calculate the	13
times higher than	13
and biological activities	13
molecular mechanisms of	13
the dynamics of	13
synthesized and tested	13
li et al	13
saturated fatty acids	13
are capable of	13
peptides and the	13
human umbilical vein	13
in rat liver	13
an anticancer drug	13
binding domain of	13
in aqueous media	13
in the colon	13
synthesis of new	13
total number of	13
the replacement of	13
the gm activator	13
a significant effect	13
was observed with	13
peripheral blood mononuclear	13
they do not	13
in normal human	13
in the extracellular	13
the coupling of	13
cd and cd	13
has been established	13
by virtue of	13
purifi ed by	13
gene expression of	13
in this communication	13
was based on	13
each amino acid	13
aim was to	13
the recovery of	13
of the expression	13