quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram	frequency
severe acute respiratory syndrome	158
acute respiratory syndrome coronavirus	102
in patients with covid	79
of angiotensin converting enzyme	73
in the treatment of	71
for the treatment of	65
angiotensin ii type receptor	65
acute respiratory distress syndrome	59
angiotensin ii receptor blockers	52
in the presence of	52
has been shown to	52
of severe acute respiratory	48
ace inhibitors and arbs	46
and angiotensin ii receptor	45
converting enzyme inhibitors and	44
middle east respiratory syndrome	41
enzyme inhibitors and angiotensin	40
in the absence of	38
as well as the	38
and angiotensin receptor blockers	36
inhibitors and angiotensin receptor	35
the use of ace	33
on the basis of	32
as compared to cont	32
ang ii to ang	31
angiotensin i to angiotensin	30
on the other hand	30
in patients with hae	30
in the united states	29
of ace in the	29
east respiratory syndrome coronavirus	29
angiotensin converting enzyme inhibitors	29
the preprint in perpetuity	28
a license to display	28
the copyright holder for	28
medrxiv a license to	28
to display the preprint	28
who has granted medrxiv	28
copyright holder for this	28
license to display the	28
display the preprint in	28
has granted medrxiv a	28
holder for this preprint	28
granted medrxiv a license	28
use of ace inhibitors	28
in the regulation of	27
the role of ace	27
been shown to be	26
as a result of	26
patients with heart failure	26
patients with coronavirus disease	26
the central nervous system	25
have been shown to	25
the renin angiotensin system	25
ace inhibitors or arbs	25
the severe acute respiratory	24
inhibitors and angiotensin ii	24
of patients infected with	24
in addition to the	23
was significantly increased in	23
compared to cont mice	23
of ang ii to	23
enzyme inhibition and angiotensin	22
a functional receptor for	22
in the case of	22
respiratory syndrome coronavirus infection	21
the risk of covid	21
effects of ace inhibitors	21
the angiotensin converting enzyme	21
and the risk of	21
a retrospective cohort study	21
in spontaneously hypertensive rats	21
european society of cardiology	21
role of ace in	21
the c nh gene	21
was found to be	21
vascular smooth muscle cells	21
early and late stages	21
angiotensin i converting enzyme	20
functional receptor for the	20
a wide range of	20
was not certified by	20
for this preprint this	20
an important role in	20
the world health organization	20
preprint this version posted	20
in db mice at	20
in patients with severe	20
is the author funder	20
this preprint this version	20
which was not certified	20
this version posted june	20
converting enzyme inhibition and	20
not certified by peer	20
certified by peer review	20
the european society of	20
in patients with heart	19
role of the renin	19
in patients with chronic	19
clinical characteristics of coronavirus	19
in patients with hypertension	19
of patients with covid	19
in patients with diabetes	19
the treatment of hypertension	19
of the at receptor	19
inhibition and angiotensin ii	19
characteristics of coronavirus disease	19
at the time of	18
the presence of a	18
converting enzyme is a	18
in the pathogenesis of	18
of ace and ace	18
in the development of	18
of coronavirus disease in	18
ii receptor blockers on	18
systematic review and meta	18
the angiotensin ii type	18
coronavirus disease in china	18
inhibitors in patients with	18
converts angiotensin i to	18
the spike protein of	18
it is important to	18
is a functional receptor	18
with the use of	18
the treatment of covid	18
role of angiotensin converting	17
ace activity in db	17
in a variety of	17
american college of cardiology	17
a role in the	17
of ace inhibitors or	17
receptor for the sars	17
ang i to ang	17
ace inhibitor and arb	16
has been reported to	16
regulator of heart function	16
levels of ang ii	16
converting enzyme protects from	16
conversion of ang ii	16
with novel coronavirus in	16
of the angiotensin ii	16
receptor blockers on cardiac	16
essential regulator of heart	16
significantly increased in db	16
increased in db mice	16
ace ace activity ratio	16
actions of ang ii	16
in the context of	16
of the renin angiotensin	16
for the sars coronavirus	16
blockers on cardiac angiotensin	16
of human angiotensin i	16
of patients with hae	16
and tmprss and is	16
is involved in the	16
of the ras in	16
an essential regulator of	16
enzyme is a functional	16
protects from severe acute	15
there is no evidence	15
the american college of	15
a clinically proven protease	15
efficacy and safety of	15
is an essential regulator	15
cloning and functional expression	15
depends on ace and	15
with severe acute respiratory	15
converting enzyme in the	15
ace and tmprss and	15
by a clinically proven	15
cell entry depends on	15
crucial role of angiotensin	15
blocked by a clinically	15
no reuse allowed without	15
as well as in	15
is blocked by a	15
tmprss and is blocked	15
on ace and tmprss	15
clinically proven protease inhibitor	15
effects of ang ii	15
a systematic review and	15
of ace inhibitors and	15
of ang ii in	15
and is blocked by	15
at increased risk for	15
severe acute lung failure	15
reuse allowed without permission	15
entry depends on ace	15
a crucial role of	15
ace inhibitors and arb	15
mortality in patients with	15
from severe acute lung	15
ang ii in the	14
in the setting of	14
vitro and in vivo	14
play a role in	14
for disease control and	14
increase the risk of	14
the use of arbs	14
a human homolog of	14
disease control and prevention	14
ace protein expression was	14
enzyme is an essential	14
and risk of covid	14
functional expression as a	14
the role of the	14
enzyme protects from severe	14
system blockers and the	14
i to angiotensin ii	14
insulin administration did not	14
in contrast to the	14
ang ii and ang	14
infected with novel coronavirus	14
patients with hereditary angioedema	14
patients with hypertension hospitalized	14
patients with hypertension and	14
in acute respiratory distress	14
db mice at early	14
similar to that of	14
and functional expression as	14
in vitro and in	14
at and at receptors	13
at early and late	13
in the course of	13
it has been suggested	13
for the management of	13
has been suggested that	13
hydrolysis of biological peptides	13
features of patients infected	13
in patients with type	13
expression as a captopril	13
increased risk for covid	13
are patients with hypertension	13
in the management of	13
of middle east respiratory	13
it has been shown	13
mortality of adult inpatients	13
course and risk factors	13
functional receptor for sars	13
adult inpatients with covid	13
i and ang ii	13
patients infected with novel	13
similar to those of	13
diabetes mellitus at increased	13
ii receptor blockers with	13
clinical course and risk	13
risk factors for mortality	13
angiotensin converting enzyme inhibition	13
clinical features of patients	13
in a rat model	13
for mortality of adult	13
in patients with hereditary	13
factors for mortality of	13
biological peptides by human	13
system inhibitors in patients	13
the c inhibitor gene	13
a risk factor for	13
ang i and ang	13
and risk factors for	13
patients with severe covid	13
a key role in	13
regulation of blood pressure	13
of adult inpatients with	13
with left ventricular dysfunction	13
angiotensin i and bradykinin	13
of biological peptides by	13
was associated with a	13
and diabetes mellitus at	13
hypertension and diabetes mellitus	13
is associated with increased	13
of ang ii and	13
used for the treatment	13
critically ill patients with	13
with hypertension and diabetes	13
human homolog of angiotensin	13
mellitus at increased risk	13
patients with left ventricular	12
of the c nh	12
therapy in patients with	12
an angiotensin ii receptor	12
the effects of ace	12
benefits of ace inhibition	12
peptides by human angiotensin	12
c esterase inhibitor deficiency	12
of angiotensin ii type	12
with acute respiratory distress	12
two homologous domains of	12
of the novel coronavirus	12
inhibitors angiotensin receptor blockers	12
of the active site	12
chronic obstructive pulmonary disease	12
components of the ras	12
death in patients with	12
in the central nervous	12
the risk of sars	12
receptor for sars coronavirus	12
ace inhibitors and at	12
the functional receptor for	12
use of angiotensin converting	12
the two homologous domains	12
administration did not modify	12
in a mouse model	12
that the use of	12
inhibitors and risk of	12
to the use of	12
domains of human angiotensin	12
the efficacy and safety	12
tissue distribution of ace	12
an increased risk of	12
is one of the	12
in patients with coronavirus	12
converting enzyme is an	12
it is possible that	12
homologous domains of human	12
the conversion of ang	11
patients with novel coronavirus	11
and vascular smooth muscle	11
distribution of ace protein	11
also been shown to	11
angiotensin ii receptor blocker	11
first step in understanding	11
the structure of the	11
in understanding sars pathogenesis	11
from the cell surface	11
angiotensin converting enzyme in	11
in addition to its	11
a first step in	11
novel coronavirus in wuhan	11
the active sites of	11
the activity of the	11
it is reasonable to	11
the formation of ang	11
no conflict of interest	11
and the presence of	11
spike protein of sars	11
in the active site	11
the authors declare that	11
the end of the	11
step in understanding sars	11
in the metabolism of	11
studies have shown that	11
the effects of the	11
of critically ill patients	11
the right coronary artery	11
aldosterone system inhibitors in	11
effects of ace inhibition	11
stage as compared to	11
to be associated with	11
converting enzyme inhibitors angiotensin	11
blockers and the risk	11
converting enzyme activity in	11
ace ang ii at	11
in a patient with	11
with ace inhibitors and	11
the risk of severe	11
the clinical course of	11
mice at early and	11
expression profiling of ace	11
have a role in	11
between ace inhibitors and	11
in vascular smooth muscle	10
left ventricular dysfunction after	10
protein expression was significantly	10
crystal structure of the	10
in hospitalized patients with	10
the two active sites	10
of ace inhibitor therapy	10
converting enzyme and angiotensin	10
a mouse model of	10
expression was significantly increased	10
may contribute to the	10
mortality among patients with	10
ang i and ii	10
chinese center for disease	10
to be involved in	10
db as compared to	10
with chronic heart failure	10
of the mas receptor	10
a member of the	10
at receptors in the	10
rats with myocardial infarction	10
a major role in	10
center for disease control	10
may be involved in	10
at the end of	10
on the role of	10
effect of ace inhibition	10
ace and ace in	10
plays an important role	10
with mortality among patients	10
patients infected with sars	10
of angiotensin ii receptor	10
patients with chronic heart	10
is highly expressed in	10
syndrome coronavirus spike protein	10
the c domain of	10
and severe acute respiratory	10
conversion of ang i	10
are both catalytically active	10
as shown in fig	10
angiotensin ii receptor antagonist	10
hypertension and heart failure	10
enzyme inhibitors angiotensin receptor	10
did not modify ace	10
had no effect on	10
ace inhibitors and angiotensin	10
aldosterone system blockers and	10
respiratory syndrome coronavirus spike	10
in patients with left	10
activity in db mice	10
treated with ace inhibitors	10
with an increase in	10
system inhibitors and risk	10
in the brain of	10
the ras in the	10
the discovery of ace	10
of ang i to	10
at the level of	9
effect of ace inhibitors	9
it was shown that	9
a potent inhibitor of	9
of recombinant human angiotensin	9
converting enzyme are both	9
in vascular endothelial cells	9
the discovery of the	9
from the venom of	9
statement addresses concerns re	9
ventricular dysfunction after myocardial	9
hospitalized patients with novel	9
the presence of an	9
of the reninangiotensin system	9
the basis of the	9
of inpatient use of	9
lung injury induced by	9
using raas antagonists in	9
blockers with mortality among	9
for the development of	9
have been reported in	9
by the action of	9
the severity of covid	9
in patients with acute	9
at r c allele	9
among patients with hypertension	9
the n domain of	9
raas antagonists in covid	9
our understanding of the	9
by severe acute respiratory	9
is identical to the	9
declare that they have	9
the chinese center for	9
hypertension hospitalized with covid	9
of the ras and	9
formation of ang ii	9
aldosterone system inhibitors and	9
isolation and characterization of	9
observed in patients with	9
the activation of the	9
and potential therapeutic target	9
of hospitalized patients with	9
a higher risk of	9
activation of factor xii	9
converting enzyme inhibition on	9
effects of the ace	9
the intensive care unit	9
association of inpatient use	9
the sympathetic nervous system	9
associated with an increased	9
with hypertension hospitalized with	9
expression of ace in	9
treatment with ace inhibitors	9
in animal models of	9
is responsible for the	9
that they have no	9
plays a role in	9
of ace inhibition in	9
ace inhibitors or arb	9
position statement of the	9
dysfunction after myocardial infarction	9
associated with a higher	9
the benefits of ace	9
receptor blockers with mortality	9
was shown to be	9
been shown to have	9
angiotensin converting enzyme inhibitor	9
patients with type diabetes	9
of the effects of	9
the regulation of the	9
the regulation of blood	9
of the european society	9
an increase in ace	9
enzyme are both catalytically	9
hyperoxia with normoxic recovery	9
hfsa acc aha statement	9
of angiotensin i and	9
mortality and morbidity in	9
molecular mechanisms and potential	9
by the use of	9
may be associated with	9
mechanisms and potential therapeutic	9
made available under a	8
with a new coronavirus	8
pneumonia outbreak associated with	8
type i and type	8
there were no differences	8
endothelial nitric oxide synthase	8
effects of angiotensin ii	8
a negative regulator of	8
very severe lethal disease	8
i and type ii	8
acc aha statement addresses	8
and angiotensin converting enzyme	8
a better understanding of	8
in the control of	8
increase in blood pressure	8
esc council on hypertension	8
treatment of patients with	8
aha statement addresses concerns	8
at r and at	8
has also been shown	8
which was not peer	8
at the same time	8
of the mitral valve	8
council on hypertension on	8
the presence of ace	8
r and at r	8
ace i d polymorphism	8
quantitative mrna expression profiling	8
available under a author	8
late stage as compared	8
patients with hae have	8
of angiotensin ii receptors	8
the esc council on	8
of probable bat origin	8
of the ang ii	8
heart failure with reduced	8
conversion of angiotensin i	8
outbreak associated with a	8
be due to the	8
it should be noted	8
polymorphism is associated with	8
induced acute lung injury	8
and characterization of a	8
license it is made	8
on the surface of	8
is supplied by the	8
has been identified as	8
one of the most	8
of the esc council	8
the beneficial effects of	8
on the x chromosome	8
activity ratio in db	8
a rat model of	8
is made available under	8
of ace inhibitors on	8
and mortality in covid	8
increased risk of covid	8
it is made available	8
in a number of	8
new coronavirus of probable	8
renin angiotensin system in	8
of ace activity in	8
in the heart and	8
in critically ill patients	8
with chronic kidney disease	8
a new coronavirus of	8
in the c inhibitor	8
coronavirus of probable bat	8
to an increase in	8
the presence of the	8
angiotensin ii receptor type	8
the absence of a	8
homologue of angiotensin converting	8
in hypertensive patients with	8
of women with hae	8
ace activity ratio in	8
that there is no	8
two active sites of	8
have been associated with	8
activity is reduced in	8
on hypertension on ace	8
gp recorded diagnosis of	8
patients with cardiovascular disease	8
international license it is	8
converting enzyme from the	8
that ace inhibitors and	8
and is associated with	8
identical to the c	8
angiotensin receptor blockers and	8
db and cont mice	8
statement of the esc	8
and late stages of	8
has been reported in	8
not been shown to	8
a wide variety of	8
in health and disease	8
authors declare that they	8
by the severe acute	8
a novel homologue of	8
novel homologue of angiotensin	8
in the general population	8
with reduced ejection fraction	8
of angiotensin ii in	8
the use of aceis	8
of the two active	8
of the spike protein	8
high molecular weight kininogen	8
under a author funder	8
it is difficult to	8
associated with a new	8
as well as their	8
both early and late	8
of angiotensin i converting	8
the at r c	8
angiotensin receptor blockers on	8
for a wide range	8
mrna expression profiling of	8
at late stage as	8
in rats with myocardial	8
of the ace gene	8
a pneumonia outbreak associated	8
at higher risk for	8
a significant role in	8
may be due to	8
converting enzyme inhibition in	8
inpatient use of angiotensin	8
for the use of	8
failure with reduced ejection	8
of the effect of	8
the left and right	8
by the spike protein	8
axes of the renin	8
important role in the	8
of a report of	7
esterase inhibitor deficiency workshop	7
study clinical characteristics of	7
to viral loads and	7
arbs or ace inhibitors	7
is a natural and	7
the function of the	7
diagnosis and treatment of	7
inhibition in patients with	7
ace and ace activity	7
specific substrate of the	7
of the american college	7
db mice at late	7
risk of severe covid	7
been identified as a	7
ii type receptor in	7
of transforming growth factor	7
the hemoregulatory peptide n	7
pro is a natural	7
mice at late stage	7
and important lessons from	7
substrate of the n	7
loads and lung injury	7
the total number of	7
treatment and prevention of	7
infected patients linked to	7
be involved in the	7
converting enzyme gene insertion	7
disease in china clinical	7
natural and specific substrate	7
ace activity in the	7
of the left ventricle	7
patients with diabetes mellitus	7
is likely to be	7
mediates regulated ectodomain shedding	7
risk of icu admission	7
for the first time	7
ii type receptor blockade	7
as compared to the	7
the effect of ace	7
enalapril in patients with	7
identification and characterization of	7
regulated ectodomain shedding of	7
which is replaced by	7
vasoprotective axes of the	7
by bork et al	7
a report of cases	7
of cases from the	7
from the chinese center	7
has been shown that	7
enzyme gene insertion deletion	7
from the coronavirus disease	7
and an increase in	7
an ace inhibitor or	7
by the world health	7
for the recognition of	7
china clinical characteristics of	7
the time of the	7
entry into the host	7
to the development of	7
physiological relevance and therapeutic	7
between the use of	7
with ace inhibitor therapy	7
the development of a	7
risk factors associated with	7
prevention and treatment of	7
entry of the virus	7
the catalytic zinc ion	7
shown to be effective	7
and therapeutic implications in	7
of the b receptor	7
of acute respiratory distress	7
outcomes in patients with	7
was associated with increased	7
lessons from the coronavirus	7
relevance and therapeutic implications	7
ang ii levels were	7
heart failure and ischaemic	7
food and drug administration	7
characteristics and outcomes of	7
shedding of the severe	7
ncov infected patients linked	7
viral loads and lung	7
with the b receptor	7
the components of the	7
to be effective in	7
of and important lessons	7
treatment of hypertension and	7
vivo and in vitro	7
clinical course of sars	7
the therapeutic benefits of	7
of death in patients	7
in the lungs of	7
linked to viral loads	7
a large number of	7
the novel coronavirus from	7
terminal active site of	7
insulin administration significantly decreased	7
of angiotensin i to	7
and specific substrate of	7
in vivo and in	7
and congestive heart failure	7
patients with acquired c	7
in the gastrointestinal tract	7
angiotensin ii receptor subtypes	7
no changes were observed	7
therapeutic implications in cardiovascular	7
angiotensin ii in the	7
characteristics of hospitalized patients	7
mice as compared to	7
angiotensin converting enzyme ii	7
hypertensive and kidney diseases	7
late stages as compared	7
of reactive oxygen species	7
ace expression in the	7
viral entry into the	7
ectodomain shedding of the	7
and ischaemic heart disease	7
the entry of the	7
levels of ang i	7
as part of the	7
levels of ace activity	7
of ace inhibitors arbs	7
of c nh gene	7
in cardiovascular and renal	7
decrease in blood pressure	7
cases from the chinese	7
characteristics of and important	7
mechanism of action of	7
components of the renin	7
clinical and biochemical indexes	7
associated with acute respiratory	7
the at receptor is	7
may play a role	7
of the interventricular septum	7
blockade of the renin	7
and late stages as	7
increased expression of ace	7
hospitalized patients with covid	7
there is evidence that	7
of hereditary angioneurotic oedema	7
have no conflict of	7
stages as compared to	7
role in the regulation	7
summary of a report	7
gene insertion deletion polymorphism	7
the setting of covid	7
it is used for	7
novel coronavirus in the	7
the presence of at	7
induced lung injury angiotensin	7
the treatment of patients	7
the hungarian hae center	7
an at receptor antagonist	7
in the cleavage of	7
clinical trial of recombinant	7
of patients admitted to	7
of the contact system	7
important lessons from the	7
has been associated with	7
report of cases from	7
host cell entry of	7
and biochemical indexes from	7
play a key role	7
the potential influence of	7
the vasoprotective axes of	7
patients linked to viral	7
the effects of angiotensin	7
with an increased risk	7
and smooth muscle cells	7
a natural and specific	7
active site of human	7
clinical characteristics of hospitalized	7
the n and c	7
the action of ace	7
failure and ischaemic heart	7
vascular endothelial growth factor	7
of the use of	6
were exposed to hyperoxic	6
ace activity ratio was	6
effect of angiotensin ii	6
potentiation of the bk	6
studies are required to	6
of these drugs in	6
ill patients with covid	6
morbidity in patients with	6
with the development of	6
are at higher risk	6
in the s subsite	6
important for inhibitor binding	6
late stages of diabetes	6
onset and severity of	6
angiotensin ii at receptor	6
the basis of this	6
on the potential influence	6
this is consistent with	6
ang ii levels in	6
structures reveal a large	6
the b receptor and	6
the formation of the	6
the role of angiotensin	6
of the presence of	6
response to ang ii	6
of novel coronavirus pneumonia	6
of angiotensin ii on	6
to hyperoxic or normoxic	6
that aceis and arbs	6
the effective refractory period	6
characteristics of cases of	6
a role for the	6
disease and icu admission	6
the breakdown of bradykinin	6
generation of reactive oxygen	6
was significantly higher in	6
in combination with the	6
patients receiving ace inhibitors	6
a variety of tissues	6
the renin prorenin receptor	6
severity of severe acute	6
such as ace inhibitors	6
or risk of death	6
the left circumflex artery	6
the plasma membrane of	6
has not yet been	6
highly expressed in the	6
role for ace in	6
blockers as tentative sars	6
of fatal outcomes of	6
angiotensin converting enzyme from	6
ratio in db mice	6
it is associated with	6
the treatment of heart	6
outcomes of patients with	6
has led to the	6
disease in patients with	6
with c inhibitor deficiency	6
a new target for	6
report of the american	6
and function of the	6
fatal outcomes of patients	6
and activation of the	6
in patients with symptomatic	6
is not associated with	6
em structure of the	6
of morbidity and mortality	6
the activity of pgl	6
pilot clinical trial of	6
in angiotensin peptide metabolism	6
the venom of bothrops	6
is a potent inhibitor	6
cardiovascular implications of fatal	6
activity ratio was significantly	6
patients treated with ace	6
of the s protein	6
better understanding of the	6
in the processing of	6
of the m family	6
converting enzyme inhibitors in	6
t t t t	6
an angiotensin converting enzyme	6
the level of the	6
the crystal structure of	6
the receptor binding domain	6
of the virus and	6
the isolated perfused rat	6
angiotensin receptor neprilysin inhibitor	6
study of patients with	6
in the brain and	6
the s and s	6
the conversion of angiotensin	6
is located on chromosome	6
vascular smooth muscle cell	6
left ventricular hypertrophy in	6
either ace inhibitors or	6
of the ras system	6
in the shr kidney	6
reduction of blood pressure	6
the interaction of ace	6
european society of hypertension	6
in db as compared	6
of the n domain	6
to the formation of	6
of ace inhibition on	6
blockers on onset and	6
the expression of ace	6
to a lesser extent	6
therapeutic benefits of ace	6
myocardial infarction in patients	6
cells were exposed to	6
the number of deaths	6
omapatrilat and enalapril in	6
modify ace protein expression	6
entry into target cells	6
effect of angiotensin converting	6
increase of ace activity	6
protein expression in db	6
was approved by the	6
in patients with cardiovascular	6
function in patients with	6
role in the pathogenesis	6
levels of ace and	6
imr cells were exposed	6
and morbidity in patients	6
and ang ii levels	6
in db mice in	6
in the formation of	6
have been found to	6
is a potent vasoconstrictor	6
of an ace inhibitor	6
and outcomes of critically	6
treatment of heart failure	6
an essential role in	6
a broad spectrum of	6
in blood pressure regulation	6
it is clear that	6
the levels of ace	6
in a study of	6
inhibitor binding and catalysis	6
the management of arterial	6
task force for the	6
and enalapril in patients	6
ace ace activity in	6
trial of recombinant human	6
viewpoint on the potential	6
and tissue levels of	6
were associated with a	6
of ace expression in	6
should be avoided in	6
potential influence of angiotensin	6
epithelial cells of the	6
with angiotensin converting enzyme	6
hyperoxic or normoxic gas	6
severity or risk of	6
an increase in the	6
of the right ventricle	6
the concentration of c	6
not modify ace protein	6
ii type receptor antagonist	6
of blood pressure and	6
the entry of sars	6
exposed to hyperoxic or	6
and clinical characteristics of	6
for the diagnosis and	6
of blood pressure regulation	6
use of aceis arbs	6
the drosophila ace orthologous	6
for inhibitor binding and	6
i to ang ii	6
with an ace inhibitor	6
used for treatment of	6
domain of somatic ace	6
should be noted that	6
a role in reproduction	6
the left anterior descending	6
there was no evidence	6
domain inhibitors of angiotensin	6
on angiotensin and bradykinin	6
activity of the ace	6
in the generation of	6
the potentiation of the	6
cloning and expression of	6
patients with hae are	6
be used for the	6
is no evidence to	6
a high level of	6
mice in both early	6
of the active sites	6
of the action potential	6
patients were treated with	6
in china clinical characteristics	6
into the rbd ace	6
motion important for inhibitor	6
in the prefusion conformation	6
a single amino acid	6
physiology of local renin	6
on onset and severity	6
d and at r	6
receptor blockers on onset	6
by the presence of	6
with coronary artery disease	6
production of nitric oxide	6
in patients treated with	6
risk of death in	6
with the exception of	6
of the angiotensin i	6
of cardiology american heart	6
c domain of sace	6
a critical role in	6
ratio was significantly increased	6
on mortality and morbidity	6
risk of ischemic stroke	6
in patients with a	6
in the spike protein	6
the ace ang ii	6
implications of fatal outcomes	6
were found to be	6
the levels of ang	6
clinical characteristics of cases	6
as a consequence of	6
increases the risk of	6
management of arterial hypertension	6
with severe coronavirus disease	6
are involved in the	6
blockade of angiotensin ii	6
of aceis and arbs	6
college of cardiology american	6
ace protein expression in	6
of interest the authors	6
between db and cont	6
specific substrate and c	6
conversion of big et	6
the diagnosis and treatment	6
to the pathogenesis of	6
virus entry into the	6
structure of the n	6
of the renin prorenin	6
inhibitors and arbs in	6
been implicated in the	6
the understanding of the	6
ace and neprilysin in	6
a review of the	6
a pilot clinical trial	6
should not be used	6
converting enzyme and its	6
treatment of acute attacks	6
for patients with hae	6
angiotensin receptor blockers have	6
angiotensin receptor blockers as	6
a viewpoint on the	6
was found in the	6
patients with coronary artery	6
and angiotensin ii type	6
a report of the	6
have not been shown	6
it acts as a	6
review of the literature	6
and characteristics of patients	6
expression in db mice	6
inhibitors of the renin	6
patients with chronic kidney	6
with type diabetes and	6
enzyme in acute respiratory	6
stages of diabetes as	6
reprinted with permission from	6
use of these drugs	6
and severity of severe	6
respiratory distress syndrome and	6
cardiology american heart association	6
in acute lung injury	6
the two domains of	6
outcomes of critically ill	6
have been described in	6
converting enzyme gene family	6
a study of patients	6
of ang i and	6
db mice in both	6
it was suggested that	6
receptor blockers as tentative	6
in the pathophysiology of	6
of diabetes as compared	6
diabetes as compared to	6
of the ace inhibitor	6
in both early and	6
in patients who are	6
no differences in ace	6
to increased levels of	6
to the intensive care	6
the protective role of	5
protective role of ace	5
a dose of mg	5
and the cellular protease	5
and middle east respiratory	5
the angiotensin ii at	5
with mild to moderate	5
after myocardial infarction by	5
converting enzyme by the	5
effective in the treatment	5
the stability of the	5
between the two groups	5
patients with acute respiratory	5
jurisdictional claims in published	5
ras in the gastrointestinal	5
the online version of	5
diabetic kidney disease and	5
adjusting for a wide	5
morbidity and mortality in	5
international committee on taxonomy	5
administration of ace inhibitors	5
a central role in	5
angiotensin converting enzyme gene	5
as shown in table	5
and the cardiovascular system	5
on the regulation of	5
of the intestinal wall	5
risk factor for covid	5
in normotensive and hypertensive	5
patients with symptomatic heart	5
a vital role in	5
as a risk factor	5
on the use of	5
likely to have a	5
of amino acids with	5
associated with a significantly	5
was not associated with	5
is located on the	5
the ace d d	5
been reported to be	5
treatment of hereditary angioedema	5
associated with severe acute	5
of patients with coronavirus	5
epidemiological and clinical characteristics	5
gene is located on	5
administered to patients with	5
for angiotensin converting enzyme	5
spike in the prefusion	5
a severe exacerbation of	5
many different cell types	5
domain of human ace	5
and inhibition of ace	5
and ace in the	5
the impact of the	5
the epidemiological characteristics of	5
the discovery of angiotensin	5
a reduced risk of	5
have been identified as	5
management of patients with	5
angiotensin system inhibitors with	5
potential conflict of interest	5
in type i hereditary	5
entry into host cells	5
outbreak of novel coronavirus	5
virus origins and receptor	5
epidemiology of novel coronavirus	5
study in patients with	5
the beginning of the	5
uncarine f and uncaric	5
which is responsible for	5
differences in substrate specificity	5
receptor in angiotensin ii	5
patients with severe acute	5
acting on the ras	5
is an endogenous ligand	5
production and cellular responses	5
administration significantly decreased ace	5
the importance of ace	5
catalytic zinc ion is	5
the creative commons attribution	5
can be activated by	5
is consistent with the	5
with acute myocardial infarction	5
on mortality in patients	5
in a cohort of	5
inhibitors with severity or	5
the american heart association	5
online version of this	5
properties of the angiotensin	5
hypertension of the european	5
interface of the rbd	5
ace and ace enzymes	5
inhibitors and at r	5
at the p position	5
the activity of ace	5
influenza a h n	5
as compared to those	5
presence or absence of	5
beneficial effects of ace	5
risk factors for death	5
associated with increased risk	5
maps and institutional affiliations	5
infarction by blockade of	5
with the novel coronavirus	5
which is available to	5
than the white group	5
activity in patients with	5
the home therapy program	5
interest the authors declare	5
of the creative commons	5
about the role of	5
after acute myocardial infarction	5
at a dose of	5
version of this article	5
the development of nsmis	5
pivotal role of the	5
of a cdna encoding	5
modulator of the renin	5
what is the evidence	5
the majority of patients	5
characteristics of an outbreak	5
the high level of	5
tissue levels of ang	5
harmful in the covid	5
seen in patients with	5
attacks in patients with	5
as well as a	5
is thought to be	5
plays a major role	5
the recognition of the	5
other members of the	5
is not inhibited by	5
enzyme after myocardial infarction	5
protease tmprss for entry	5
for the formation of	5
f and uncaric acid	5
of human and drosophila	5
of cases of novel	5
bound to captopril and	5
at r and the	5
reported in patients with	5
has been implicated in	5
member of the m	5
in heart failure patients	5
of the follicle wall	5
cellular responses to renin	5
the posterior descending artery	5
on the cell membrane	5
to captopril and lisinopril	5
coronavirus pneumonia in wuhan	5
ace inhibition may be	5
transmission dynamics in wuhan	5
the rupture of the	5
of nitric oxide and	5
angiotensin system in human	5
in accordance with the	5
the frequency and severity	5
ligand for the g	5
with severity or risk	5
the loss of ace	5
of the role of	5
by the fact that	5
springer nature remains neutral	5
a key modulator of	5
with a mortality rate	5
for virus origins and	5
conflict of interest the	5
on the cell surface	5
have an important role	5
of cardiology and the	5
with the ace inhibitor	5
captopril on mortality and	5
of at receptor blockade	5
of ace inhibitor and	5
has been demonstrated in	5
in the last decade	5
a randomized clinical trial	5
of the disease and	5
of left ventricular dysfunction	5
hypertension hospitalized for coronavirus	5
been reported in patients	5
in the human heart	5
alone or in combination	5
drugs and risk of	5
to the human ace	5
the clinical manifestations of	5
key modulator of the	5
by blockade of angiotensin	5
renin angiotensin system and	5
blocking drugs perhaps be	5
the complexity of the	5
site of human angiotensin	5
distributed under the terms	5
sodium and water retention	5
for treatment of covid	5
by ace inhibition in	5
no effect on the	5
patients hospitalized with covid	5
inhibition on angiotensin and	5
counts per million reads	5
an acute attack therapy	5
implications for virus origins	5
were shown to be	5
have not yet been	5
disease and ulcerative colitis	5
committee on taxonomy of	5
of pneumonia associated with	5
for the g protein	5
is usually associated with	5
the conversion of big	5
of ace and the	5
converting enzyme inhibitory peptides	5
role of angiotensin ii	5
structure of the human	5
in the risk of	5
a small number of	5
of the sympathetic nervous	5
the use of either	5
in patients who have	5
for ace and ace	5
studies are needed to	5
of the actions of	5
the balance between the	5
structure of the angiotensin	5
and arbs in the	5
converting enzyme in acute	5
the effects of ang	5
deduced amino acid sequences	5
the hypotensive effect of	5
after the onset of	5
the aim of this	5
its homologue ace and	5
american heart association task	5
as ace inhibitors and	5
and blood pressure in	5
in patients presenting with	5
blood flow to the	5
reduced risk of covid	5
that some of the	5
comorbidities in patients with	5
and the severity of	5
of acute lung injury	5
is released into the	5
a potential target for	5
there was a significant	5
on taxonomy of viruses	5
ace and the cellular	5
heart failure and reduced	5
major role in the	5
of the two domains	5
at present there is	5
the ratio of ang	5
a novel coronavirus associated	5
admitted to the intensive	5
association task force on	5
of the components of	5
in the degradation of	5
or normoxic gas as	5
ncov spike in the	5
as well as other	5
side effects associated with	5
of the severe acute	5
ace in individuals with	5
and ace activity in	5
clinical characteristics of patients	5
with severe aortic stenosis	5
of left ventricular hypertrophy	5
to be increased in	5
be harmful in the	5
myocardial infarction by blockade	5
of the c inhibitor	5
hospitalized for coronavirus disease	5
cardiovascular morbidity and mortality	5
ace is highly expressed	5
and mortality in patients	5
are similar to those	5
two domains of sace	5
plays a key role	5
as described in figure	5
van kats et al	5
the involvement of the	5
of sodium and water	5
ace inhibitor therapy in	5
of angiotensin ii and	5
is a key modulator	5
associated with an increase	5
the vascular smooth muscle	5
antihypertensive drugs and risk	5
more likely to have	5
the safety and efficacy	5
patients at high risk	5
in the cardiovascular system	5
ace in the renal	5
present there is no	5
be related to the	5
angiotensin i into angiotensin	5
could be prevented by	5
ace d d genotype	5
by the novel coronavirus	5
reveal a large hinge	5
system inhibitors with severity	5
gas as described in	5
or in combination with	5
be a risk factor	5
of blood pressure in	5
of c and c	5
may be increased by	5
the presence or absence	5
the harmful effects of	5
of novel coronavirus diseases	5
involvement of ace in	5
the effect of the	5
of acute myocardial infarction	5
manipulation of the ras	5
genomic characterisation and epidemiology	5
in the lcz group	5
of ace inhibitors in	5
might contribute to the	5
for entry into target	5
human renin and human	5
the treatment of sars	5
expression of ace and	5
calcium channel blockers are	5
angiotensin ii to angiotensin	5
reported in the literature	5
may serve as a	5
activation of the mas	5
we found that ace	5
these data suggest that	5
perhaps be harmful in	5
the binding of the	5
effects of these drugs	5
tmprss for entry into	5
the specificity of the	5
activation of the at	5
the deduced amino acid	5
in the clinical course	5
an analysis of the	5
treatment expert group for	5
of the classical ras	5
the ace inhibitor captopril	5
prorenin receptor in angiotensin	5
effect of ang ii	5
of the ras are	5
activation of the angiotensin	5
been found to be	5
the task force for	5
were no differences in	5
cellular protease tmprss for	5
use of either ace	5
frequency and severity of	5
in patients infected with	5
the antihypertensive effects of	5
outside of blood pressure	5
in the process of	5
overexpression of hnrnp f	5
of the ace axis	5
of recombinant human c	5
patients with mild to	5
an endogenous ligand for	5
n domain of human	5
the cleavage of angiotensin	5
the at receptor gene	5
characterisation and epidemiology of	5
cases of novel coronavirus	5
angiotensin converting enzyme is	5
has been detected in	5
distress syndrome and death	5
homologue ace and neprilysin	5
type i hereditary angioedema	5
endothelial and smooth muscle	5
the use of these	5
this work was supported	5
activity correlated inversely with	5
of the central nervous	5
of hypertension and heart	5
syndrome and death in	5
of the classical pathway	5
for ace in the	5
receptor ace and the	5
without eliciting reflex tachycardia	5
is present in the	5
via the at receptor	5
in support of this	5
different structural requirements for	5
with a history of	5
the first time that	5
in relation to covid	5
the treatment of chronic	5
no effect on ace	5
by angiotensin ii type	5
a proxy measure of	5
of angiotensin receptor blockers	5
a systematic review of	5
heart association task force	5
angiotensin ii production and	5
society of cardiology and	5
is implicated in the	5
factors associated with acute	5
is associated with a	5
patients admitted to the	5
are responsible for the	5
in the present study	5
a recent report by	5
the treatment of hae	5
the use of the	5
role in blood pressure	5
patients with diabetes and	5
as a receptor for	5
characteristics of patients infected	5
of angioedema associated with	5
of an outbreak of	5
shown as sticks with	5
among patients with coronavirus	5
bending motion important for	5
in new york city	5
accumulation of ang ii	5
the active site of	5
on the risk of	5
and cellular responses to	5
in the levels of	5
ang ii levels and	5
arbs and ace inhibitors	5
drugs perhaps be harmful	5
inhibitors and arbs have	5
to jurisdictional claims in	5
renin prorenin receptor in	5
the cellular protease tmprss	5
centers for disease control	5
the rbd of sars	5
the mechanism by which	5
the upper respiratory tract	5
ii production and cellular	5
does not seem to	5
the generation of angiotensin	5
is the most common	5
and at r c	5
inhibitors and arbs are	5
under the terms of	5
origins and receptor binding	5
medical treatment expert group	5
neprilysin in angiotensin peptide	5
in a hospital setting	5
the basic reproduction number	5
normoxic gas as described	5
epidemiological characteristics of an	5
in ad compared with	5
with hypertension hospitalized for	5
remains neutral with regard	5
novel coronavirus pneumonia in	5
in congestive heart failure	5
arbs are associated with	5
with symptomatic heart failure	5
and epidemiology of novel	5
inverse relationship between ace	5
regard to jurisdictional claims	5
ray structures reveal a	5
influenza h n virus	5
rupture of the follicle	5
in published maps and	5
in chronic heart failure	5
patients with hae with	5
ace and ace expression	5
neutral with regard to	5
of the activation of	5
the development of the	5
published maps and institutional	5
and its role in	5
endogenous ligand for the	5
and neprilysin in angiotensin	5
the severity of the	5
note springer nature remains	5
the treatment and prevention	5
of ang ii by	5
is based on the	5
of the sars coronavirus	5
increased ang ii levels	5
in agreement with the	5
with diabetic kidney disease	5
is often associated with	5
angiotensin ii type a	5
in the production of	5
venom of bothrops jararaca	5
is yet to be	5
avian influenza a h	5
has been found to	5
a great deal of	5
structure and function of	5
to assess the efficacy	5
nature remains neutral with	5
the epithelial cells of	5
functional conservation of the	5
both ace and ace	5
has been linked to	5
for the generation of	5
ang i or ang	5
ang ii and aldosterone	5
by binding to the	5
china medical treatment expert	5
and death in patients	5
are present in the	5
with regard to jurisdictional	5
the context of covid	5
an outbreak of novel	5
both ace inhibitors and	5
novel coronavirus associated with	5
of ace and ang	5
ace and ace activities	5
at the position of	5
and expression of an	5
in patients with coronary	5
in angiotensin ii production	5
between ace and ace	5
ace insertion deletion polymorphism	5
nonproteolytic activation of prorenin	5
does not appear to	5
the effect of angiotensin	5
sodium and water absorption	5
a crucial role in	5
of the risk of	5
the most common symptoms	5
kidney proximal tubular cells	5
claims in published maps	5
significantly higher in the	5
significant increase of ace	4
the terms of the	4
in heart failure and	4
have been used in	4
to be responsible for	4
and bradykinin peptide levels	4
the ras system and	4
the active site is	4
ace inhibitors correlates with	4
role for the enzyme	4
patients with severe disease	4
ace d d and	4
the association of sars	4
neither ace inhibitors nor	4
approved for treatment of	4
changes in blood coagulation	4
elevated ang ii levels	4
activation of the ace	4
in the control group	4
i arbs therapy was	4
infected pneumonia in wuhan	4
an important determinant of	4
right ventricular outflow tract	4
role of bradykinin in	4
the novel coronavirus sars	4
role in the treatment	4
small airway epithelia of	4
concentrate in patients with	4
mice at early stage	4
severe or very severe	4
a significant reduction of	4
in the inactivation of	4
the virus in the	4
the molecular basis of	4
follow up and p	4
a clinical trial of	4
no significant differences in	4
captopril on mortality in	4
it is necessary to	4
were found to have	4
properties and enzymatic specificities	4
as well as for	4
both in vitro and	4
hae with normal c	4
caused by severe acute	4
these two drug classes	4
the wuhan wet market	4
the role of ras	4
in engineered human tissues	4
that the majority of	4
and ace inhibitors correlates	4
been shown to reduce	4
may be found under	4
clinical trials are currently	4
contributes to the antihypertensive	4
a recent study by	4
of amino acid residues	4
angiotensin ii and the	4
of use of angiotensin	4
a total of physicians	4
the spontaneously hypertensive rat	4
of patients dying in	4
have shown that ace	4
renin angiotensin system blockers	4
purification and characterization of	4
the recognition of sars	4
lethal avian influenza a	4
ace differentially and only	4
turn is cleaved by	4
those who were infected	4
due in part to	4
first case of novel	4
unless otherwise advised by	4
be kept in mind	4
on the potentiation of	4
ace is not inhibited	4
and arbs in covid	4
withdrawn in patients with	4
in pancreas from db	4
and management of patients	4
of angiotensin ii to	4
for ace inhibitors and	4
to ang ii by	4
of randomized controlled trials	4
clinical course and outcomes	4
released into the circulation	4
after adjusting for a	4
coronavirus receptor ace and	4
rat kidney proximal tubular	4
lung injury in mice	4
to the antihypertensive effects	4
signs and symptoms of	4
coronavirus associated with severe	4
studies of sars coronavirus	4
effect on ace ace	4
the bars indicate the	4
mediator of nonallergic angioedema	4
as opposed to ace	4
tmprss and adam cleave	4
in the form of	4
the catalytic activity of	4
and the number of	4
less likely to have	4
parameters of left ventricular	4
with a variety of	4
and the role of	4
the inhibition of ace	4
blockers in patients with	4
of c esterase inhibitor	4
deletion polymorphism in the	4
to the fact that	4
db mice as compared	4
shown to be the	4
in the small airway	4
enzyme inhibits lung injury	4
and its relation to	4
binding sites in the	4
acute lung injury in	4
broad substrate specificity and	4
be one of the	4
conservation of the active	4
ang ii binds to	4
the generation of ang	4
higher levels of ace	4
heart failure survival study	4
presence of ace in	4
role of the ace	4
the angiotensin ii receptor	4
use in the treatment	4
to act as a	4
leads to the late	4
animals followed for days	4
to the late development	4
of the new coronavirus	4
in the rat brain	4
i by neutral endopeptidase	4
on the spike protein	4
and the onset of	4
between its two active	4
action of angiotensin ii	4
mediates influenza h n	4
at least in part	4
in a retrospective study	4
have been able to	4
cov and ace induces	4
the basis of these	4
potent inhibitor of angiotensin	4
all patients with hae	4
upper and lower respiratory	4
is also present in	4
ace is expressed in	4
plasma levels of ace	4
proven to be effective	4
the formation of plasmin	4
infection in younger subjects	4
angiotensin system be withdrawn	4
effect of captopril on	4
be useful in the	4
spectrophotometric assay and properties	4
of ang ii as	4
examined the effects of	4
help to explain the	4
expressed on many different	4
the results of a	4
is the most important	4
i and arb in	4
amino acids from the	4
ang ii has been	4
i and arbs in	4
on ace ace activity	4
patients receiving ace inhibitor	4
a competitive inhibitor of	4
micrograms of total protein	4
heterogeneous nuclear ribonucleoprotein f	4
system in health and	4
a gene duplication event	4
contribute to the therapeutic	4
and the immune system	4
the heart and the	4
et al found that	4
are members of the	4
a single active site	4
there is evidence of	4
catalytic domains of ace	4
pecuniary value of life	4
inhibitory effect of tgf	4
may also lead to	4
risk factors for severe	4
of ace and ece	4
of drosophila angiotensin i	4
and bradykinin peptides in	4
amino acid sequences from	4
can be used as	4
deletion polymorphism is associated	4
users of ace inhibitors	4
for ang ii and	4
inhibits lung injury induced	4
role in regulating the	4
on the severity and	4
ace has been shown	4
with increased risk of	4
the heart and kidneys	4
the use of anti	4
circulating and tissue levels	4
with a lower risk	4
ace inhibitor or arbs	4
with the cell membrane	4
acquired c inhibitor deficiency	4
axis of the renin	4
development and progression of	4
characteristics of novel coronavirus	4
be examined against sars	4
induced by respiratory syncytial	4
a comparison of the	4
effects of candesartan in	4
ace and ace have	4
in lungs from db	4
to play a role	4
the survival and ventricular	4
and cerebral amyloid angiopathy	4
have been attributed to	4
r and the ace	4
a furin cleavage site	4
and the gastrointestinal tract	4
potentiating peptides on the	4
drugs for treatment of	4
and drosophila angiotensin i	4
expression of the ace	4
a median age of	4
losartan heart failure survival	4
new roles in inflammation	4
the absence of ace	4
the cardiac action potential	4
the putative receptor of	4
the absence or presence	4
chronic use of ace	4
of severe lethal covid	4
are at increased risk	4
angiotensin system in the	4
gene expression of ace	4
patients with acute myocardial	4
and clinical implications in	4
of insect biochemistry and	4
cardiac angiotensin converting enzyme	4
the relationship between the	4
has been proposed that	4
are not recommended for	4
generation of ang ii	4
different from that of	4
reduction in ang ii	4
angiotensin and bradykinin peptide	4
the need for a	4
due to inhibition of	4
is shown as a	4
ace inhibitors have been	4
ace inhibitors versus arbs	4
and ace induces tnf	4
structure of drosophila angiotensin	4
of its spike protein	4
differences in ace ace	4
of the ace angiotensin	4
of oc or hrt	4
transforming growth factor beta	4
enzyme protects from lethal	4
is more likely to	4
the diverse range of	4
component of the renin	4
ace inhibition in heart	4
failure society of america	4
the course of the	4
ace activity was significantly	4
it was found to	4
gain entry into the	4
central role in the	4
grade soluble human ace	4
blood glucose levels in	4
of action of angiotensin	4
range of functions of	4
the association between the	4
not associated with a	4
effects of captopril on	4
and characterization of novel	4
the increase in ang	4
through activation of the	4
with aceis and arbs	4
protects against lung fibrosis	4
they have no competing	4
and ang ii are	4
influenza a virus and	4
of ace inhibition may	4
of ang ii were	4
the action potential and	4
of both ace and	4
potentiate the effects of	4
in the late phase	4
it is unclear whether	4
ace is a type	4
the small airway epithelia	4
may increase the risk	4
that the potentiation of	4
blood pressure and renal	4
through the inhibition of	4
may be useful in	4
of the tomato moth	4
expression of ace is	4
its two active sites	4
with the discovery of	4
ace inhibitor therapy was	4
active sites of human	4
not included in the	4
the use of acei	4
these data demonstrate that	4
of the present study	4
in cardiac and renal	4
their potential role in	4
related to increased levels	4
of losartan compared with	4
available to authorized users	4
enzyme inhibition on angiotensin	4
ferrario et al b	4
c nh gene anomalies	4
independent predictors of severe	4
the mas receptor in	4
in the ace gene	4
and mortality associated with	4
days after myocardial infarction	4
proxy measure of ace	4
also known as insulin	4
in hypertensive patients may	4
of severe disease and	4
inhibitory effect on the	4
epithelia of smokers and	4
infarction in patients with	4
the enzymatic activity of	4
as discussed in the	4
injury induced by respiratory	4
outcomes among patients hospitalized	4
cardiovascular complications in covid	4
and at receptor antagonists	4
a receptor for the	4
is believed to be	4
binding domain complexed with	4
clinical characteristics of novel	4
long structural studies of	4
archives of insect biochemistry	4
higher as compared to	4
the cardiovascular effects of	4
a reduction in the	4
and the at receptor	4
the existence of an	4
roles of the two	4
in patients with advanced	4
by tmprss augments entry	4
to be the most	4
enzyme and neutral endopeptidase	4
of patients with severe	4
recognition of the sars	4
be more susceptible to	4
the rest of the	4
difference between the two	4
due to the lack	4
one of the main	4
view of the ras	4
is associated with an	4
little is known about	4
is mediated by angiotensin	4
r a c polymorphism	4
management of heart failure	4
increase in cardiac output	4
arbs treatment during the	4
have significant effects on	4
is a risk factor	4
of patients in the	4
of patients with heart	4
pharmacokinetics and pharmacodynamics of	4
to the proximal tubule	4
and expression of angiotensin	4
otherwise advised by their	4
the context of the	4
inhibitors correlates with ace	4
with captopril on mortality	4
the authors note that	4
of the cardiac action	4
sites of human and	4
rate and characteristics of	4
binding to the ace	4
characterization of renal angiotensin	4
of recombinant human ace	4
are yet to be	4
the spread of the	4
ii type receptor stimulation	4
and transforming growth factor	4
type ii integral membrane	4
slope of phase depolarization	4
actions of angiotensin ii	4
even in the absence	4
crystal structure of drosophila	4
and cytokine release syndrome	4
head to head studies	4
in human fetal lung	4
have been linked to	4
as well as to	4
blood pressure and cardiac	4
the food and drug	4
enzyme in the cleavage	4
of the virus into	4
the right ventricular outflow	4
omapatrilat cardiovascular treatment vs	4
and institutional affiliations key	4
at high risk of	4
as indicated by the	4
mas receptor in the	4
at the cell surface	4
be responsible for the	4
converting enzyme bound to	4
for the novel coronavirus	4
course and outcomes of	4
proteolysis by tmprss augments	4
of severe heart failure	4
or angiotensin receptor blockers	4
in the majority of	4
can be assessed by	4
of the ace ang	4
amino acid from the	4
of total protein extracts	4
its expression in the	4
has been demonstrated to	4
is converted to ang	4
can be observed in	4
type i hereditary angio	4
the omapatrilat cardiovascular treatment	4
potential harmful effects of	4
is associated with severe	4
on the cardiovascular system	4
left ventricular outflow tract	4
was higher as compared	4
of the receptor binding	4
n and c domains	4
converting enzyme and the	4
from lethal avian influenza	4
arrival of a vaccine	4
ill patients with sars	4
as a model for	4
production and facilitates viral	4
hormone replacement therapy on	4
patients may be increased	4
is similar to that	4
of ang ii on	4
patients dying in relation	4
should not be discontinued	4
was reported to be	4
enzyme in diabetic nephropathy	4
bilateral renal artery stenosis	4
but insulin administration had	4
may be beneficial in	4
would be expected to	4
it was thought that	4
active sites of somatic	4
binding to human ace	4
b and b receptors	4
the lower respiratory tract	4
did not find any	4
compared to their respective	4
isolated from the venom	4
of the viral genome	4
with a median age	4
and human coronavirus nl	4
ace is located on	4
and the united states	4
the increased risk of	4
of bradykinin by angiotensin	4
prone spontaneously hypertensive rats	4
is associated with the	4
amino acids with a	4
a blood meal and	4
the late phase of	4
in a study conducted	4
the lack of a	4
in the first place	4
may result in the	4
as compared to their	4
plays a vital role	4
analysis based on decade	4
novel coronavirus from wuhan	4
in other physiological processes	4
downregulation of the ace	4
has been given to	4
in the s and	4
adam cleave ace differentially	4
converting enzyme in diabetic	4
that the active site	4
of a duplicated gene	4
a significant increase of	4
expert group for covid	4
entry into the cells	4
required in patients with	4
normotensive and hypertensive subjects	4
force for the management	4
cells of the kidney	4
the ace to ace	4
is available to authorized	4
receptor recognition by the	4
engineered human tissues using	4
changes were observed between	4
was based on the	4
of the t wave	4
case of novel coronavirus	4
in the late s	4
to evolutionary steps of	4
and facilitates viral entry	4
an increase in cardiac	4
of the at r	4
in the hope and	4
has been described to	4
indicate the mean value	4
structural basis for the	4
on blood pressure and	4
in the kidney of	4
coronary blood flow and	4
system be withdrawn in	4
the structure and function	4
associated with a reduced	4
amounts of micrograms of	4
found to be associated	4
of coronavirus spike proteins	4
with renin angiotensin system	4
left ventricular systolic dysfunction	4
evaluation and management of	4
on many different cell	4
which in turn is	4
in a range of	4
airway epithelia of smokers	4
study was approved by	4
systematic reviews and meta	4
is expressed on many	4
ad compared with age	4
expression and activity of	4
increase in ace activity	4
protective arms of ras	4
converting enzyme in rat	4
in two patients with	4
the basis of their	4
sites of somatic angiotensin	4
in the epithelial cells	4
in the urine of	4
effects are similar to	4
should not be administered	4
hope and europa studies	4
sequence identity with human	4
stimulation of aldosterone secretion	4
novel coronavirus infection in	4
c esterase inhibitor in	4
and in patients with	4
more than years ago	4
enzyme of rabbit lung	4
type diabetes and nephropathy	4
and the american heart	4
in patients taking ace	4
human and drosophila angiotensin	4
and chronic kidney disease	4
the first evidence of	4
and at r blockers	4
the metabolism of ang	4
with heart failure and	4
to the lack of	4
within and beyond the	4
late development of angiotensin	4
augments entry driven by	4
domain of the mammalian	4
of hereditary angioedema with	4
results of a randomized	4
potential beneficial effects of	4
correspond to evolutionary steps	4
the hope and europa	4
enzyme bound to captopril	4
the first cases of	4
in the current study	4
that is responsible for	4
enzyme inhibition in patients	4
entry into the cell	4
first time that the	4
the bradykinin b receptor	4
ang ii from ang	4
of the bradykinin receptor	4
receptor blockers with testing	4
angioedema in patients with	4
increased risk of severe	4
smooth muscle cells and	4
inflammatory cytokines such as	4
effect of hyperoxia on	4
as a second messenger	4
blood pressure in ace	4
the at receptor in	4
the high mortality rate	4
bars indicate the mean	4
angiotensin system in health	4
in an increase in	4
in ang ii levels	4
domain of human somatic	4
able to interact with	4
patients with lung cancer	4
a measure of the	4
these data suggest a	4
obstructive pulmonary disease and	4
insect biochemistry and physiology	4
clinical implications in patients	4
functions of this enzyme	4
the international committee on	4
increased ace activity in	4
were less likely to	4
domain of angiotensin i	4
type i hereditary angioneurotic	4
and adam cleave ace	4
an acute abdominal attack	4
involved in the metabolism	4
slowing the progression of	4
d d and at	4
a protective role of	4
fetal human lung fibroblasts	4
enzyme inhibitors or angiotensin	4
that the expression of	4
to die of covid	4
hae caused by c	4
inhibition may be due	4
of heart function angiotensin	4
they have no conflict	4
of free peritoneal fluid	4
agt and ang ii	4
have shown that the	4
associated with increased mortality	4
infection with sars cov	4
converting enzyme able to	4
updated information may be	4
control of blood pressure	4
presence of an ace	4
an intensive care unit	4
in the aorta of	4
insulin administration had no	4
effect of losartan compared	4
should inhibitors of the	4
cleavage site in the	4
angiotensin converting enzyme and	4
alternate promoters correspond to	4
and disseminated intravascular coagulation	4
the at b receptor	4
an open circulatory system	4
reduced ratio of ace	4
or mortality of covid	4
associated with a lower	4
chronic heart failure and	4
of either ace inhibitors	4
b and b sheets	4
in association with increased	4
in vitro substrate specificity	4
recognition by the novel	4
opposed to ace inhibitors	4
the promoter activity of	4
cd and cd t	4
only proteolysis by tmprss	4
those of ang ii	4
tmprss augments entry driven	4
as shown in figure	4
is also associated with	4
spontaneously hypertensive rats angiotensin	4
low molecular weight heparin	4
survival study elite ii	4
inhibitor of angiotensin i	4
ang ii levels are	4
with testing positive for	4
the left and the	4
the classical ras pathway	4
activity was significantly increased	4
studies were performed in	4
the treatment of acute	4
hypertensive patients may be	4
was not confirmed in	4
cardiovascular disease and covid	4
of the immune system	4
a result of the	4
cleave ace differentially and	4
in the presence or	4
of the ras with	4
retrospective cohort study clinical	4
the proximal ascending aorta	4
effects of at receptor	4
hypertension in patients with	4
to be the main	4
the function of ace	4
sites of angiotensin i	4
angiotensin system blockers and	4
the binding interface of	4
of the angiotensin converting	4
inhibitors and at receptor	4
during the course of	4
may be related to	4
compared with the white	4
deaths due to covid	4
of the left ventricular	4
is mediated by the	4
national institutes of health	4
ventricular hypertrophy in men	4
is no evidence that	4
the degradation of the	4
a treatment of covid	4
dying in relation to	4
in an effort to	4
at r a c	4
the arrival of a	4
ang ii and its	4
in patients with cirrhosis	4
to their respective cont	4
between the two classes	4
in patients with hfref	4
c nh gene mutations	4
the structure of tace	4
into the host cell	4
spike protein of the	4
in the early stage	4
inh concentration and function	4
ace inhibitors and or	4
protein of amino acids	4
the immune system of	4
presence of at least	4
system the role of	4
in ace ace activity	4
positive for coronavirus disease	4
binding interface of the	4
likely to die of	4
drosophila ace orthologous gene	4
patients with pneumonia in	4
of ang peptide formation	4
in ace activity levels	4
active sites of angiotensin	4
conversion of angiotensin ii	4
the classical pathway of	4
the spike glycoprotein of	4
of the general population	4
the reason for the	4
population reaches herd immunity	4
driven by the severe	4
contraindications to the use	4
i into angiotensin ii	4
ace inhibitors nor arbs	4
management of acute myocardial	4
steps of a duplicated	4
localization of ace in	4
correlates with ace c	4
the ace gene were	4
in the light of	4
i arbs treatment during	4
of patients with hypertension	4
angiotensin ii angiotensin ii	4
at the site of	4
blockers and the covid	4
mean incubation period of	4
arm of the ras	4
patients with hae to	4
be increased by olmesartan	4
ii from ang i	4
heart failure society of	4
of spontaneously hypertensive rats	4
two alternate promoters correspond	4
testing positive for coronavirus	4
i converting enzyme able	4
losartan compared with captopril	4
implications in patients with	4
its mechanism of action	4
at early stage as	4
angiotensin i and ii	4
promoters correspond to evolutionary	4
been shown to inhibit	4
of blood pressure lowering	4
in the proximal tubules	4
the mean value and	4
the late development of	4
is located in the	4
by ace inhibitor therapy	4
and functional characterization of	4
to the recommendation that	4
et al conducted a	4
the wall of the	4
to a decrease in	4
administration significantly increased ace	4
associated with the use	4
release of nitric oxide	4
of acute and chronic	4
is part of the	4
insertion deletion polymorphism in	4
novel coronavirus and the	4
play an important role	4
female patients with hae	4
was discovered in the	4
the influence of potentiating	4
enzyme in hypertensive patients	4
inhibitor and arb drugs	4
ang ii is a	4
converting enzyme after myocardial	4
blockers with testing positive	4
basis for the recognition	4
is shown in figure	4
bradykinin potentiation by angiotensin	4
cardiovascular and renal protection	4
dysfunction in patients with	4
entry driven by the	4
cleavage of angiotensin i	4
on the development of	4
by respiratory syncytial virus	4
i hereditary angioneurotic edema	4
converted to ang ii	4
ang ii at r	4
of the human angiotensin	4
converting enzyme as a	4
with hae type iii	4
is highly selective for	4
characterization of a new	4
as a therapeutic target	4
these data indicate that	4
converting enzyme and male	4
susceptibility of the elderly	4
diabetes is associated with	4
of these enzymes in	4
for the study of	4
the onset of the	4
evolutionary steps of a	4
the gene encoding ace	4
the ace d allele	4
harmful effects of discontinuing	4
with regard to the	4
of ace deletion polymorphism	4
absence or presence of	4
early transmission dynamics in	4
of the included studies	4
that ace inhibitors or	4
an important role of	4
have proven to be	4
on cardiovascular events in	4
the inhibitory effect of	4
other components of the	4
and activity of ace	4
was associated with an	4
an analysis based on	4
mean value and sem	4
the actions of ace	4
that the administration of	4
located on the x	4
some patients with hae	4
a diagnosis of hae	4
it is postulated that	4
short duration of action	4
induced by a blood	4
the major mediator of	4
with a reduced risk	4
ace acts as a	4
ii type a receptor	4
the gene coding for	4
of the ace ace	4
angiotensin and bradykinin peptides	4
and oxidative stress in	4
has been suggested as	4
formation in the heart	4
ace inhibitor or arb	4
to the mineralocorticoid receptor	4
a new class of	4
increasing the risk of	4
the number of cases	4
reasonable to conclude that	4
localization and expression of	4
arrival of herd immunity	4
administration had no effect	4
in turn is cleaved	4
it has been reported	4
left and the right	4
have been found in	4
angiotensin ii receptor antagonists	4
ii type receptor antagonists	4
survival and ventricular enlargement	4
to the b receptor	4