trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	654
the presence of	556
respiratory syndrome coronavirus	523
in this study	492
middle east respiratory	398
east respiratory syndrome	395
severe acute respiratory	362
the role of	360
acute respiratory syndrome	357
hepatitis c virus	344
been shown to	311
based on the	310
influenza a virus	310
due to the	309
in order to	308
the expression of	300
the number of	298
of the virus	285
according to the	279
respiratory syncytial virus	278
the development of	266
shown in figure	265
of the viral	260
one of the	253
the formation of	250
the use of	245
the cells were	241
it has been	240
infectious bronchitis virus	240
cd t cells	235
was used to	229
and respiratory syndrome	228
were infected with	223
porcine reproductive and	222
reproductive and respiratory	222
in addition to	221
of a novel	211
has been shown	208
as shown in	208
respiratory syndrome virus	205
porcine epidemic diarrhea	205
in the presence	203
the detection of	201
feline infectious peritonitis	201
the absence of	198
analysis of the	195
west nile virus	194
for h at	192
to determine the	182
the authors declare	182
shown to be	181
rift valley fever	181
compared to the	179
epidemic diarrhea virus	179
the production of	176
authors declare no	175
type i interferon	175
cells were infected	173
virus infection in	173
role in the	172
conflict of interest	169
the effect of	167
no conflict of	165
involved in the	164
the activation of	163
type i ifn	163
of viral rna	162
in response to	160
for min at	158
herpes simplex virus	156
hepatitis e virus	156
and characterization of	155
c for min	155
declare no conflict	154
associated with the	154
a total of	153
human immunodeficiency virus	153
in vitro and	152
the plasma membrane	152
is associated with	150
members of the	150
we found that	147
used as a	147
the replication of	146
is required for	146
on the other	144
in the s	144
a number of	142
structure of the	142
the other hand	142
in the absence	139
the case of	139
the majority of	137
as previously described	136
at room temperature	136
the treatment of	135
cells infected with	135
showed that the	134
has been reported	133
found to be	130
the induction of	130
was shown to	129
well as the	128
results showed that	127
was used as	126
an important role	126
expression of the	126
has also been	126
innate immune response	125
was detected in	124
activation of the	121
the present study	121
in the case	121
of middle east	120
of influenza a	119
detected in the	119
the ability of	119
characterization of a	118
have been shown	118
zikv natal rgn	118
the lack of	117
a role in	116
a variety of	115
the cell surface	114
in our study	114
antiviral activity of	112
has not been	112
and in vivo	112
such as the	112
the context of	111
in contrast to	111
vitro and in	111
the release of	110
was performed using	110
the viral genome	110
the endoplasmic reticulum	110
in cell culture	110
have shown that	109
were incubated with	108
related to the	108
were used to	108
of type i	108
of ebola virus	108
important role in	107
most of the	106
were detected in	106
in the context	106
dependent rna polymerase	106
the united states	105
of influenza virus	105
feline immunodeficiency virus	105
have also been	104
the percentage of	103
valley fever virus	103
cells in the	103
the results of	103
the inhibition of	102
to be a	102
have been reported	101
the effects of	101
is essential for	101
part of the	100
the importance of	100
c for h	100
in patients with	100
hek t cells	99
were treated with	99
the addition of	99
and n genes	98
the host cell	98
of the s	98
present in the	98
the innate immune	98
infected with the	97
as a result	96
have been identified	96
in figure a	96
vesicular stomatitis virus	95
the amino acid	95
of hepatitis c	95
similar to the	95
characterization of the	95
the identification of	95
the s subsite	94
for the detection	94
was used for	94
of severe acute	94
in the present	93
observed in the	93
of infected cells	92
activity of the	92
role of the	92
closely related to	91
in the cytoplasm	91
the risk of	90
was observed in	90
member of the	90
can be used	90
the regulation of	90
for peer review	90
was added to	89
cells were fixed	89
the level of	89
in the same	89
peer review of	89
the surface of	88
thermo fisher scientific	88
polymerase chain reaction	88
hepatitis b virus	88
end of the	88
x for peer	87
cd t cell	87
in the united	87
were transfected with	86
cells were washed	86
lower respiratory tract	86
be used to	85
of the host	85
of the sars	85
the n protein	85
identification of a	85
the amount of	85
changes in the	85
used for the	84
central nervous system	84
the s protein	84
immune response to	84
for the treatment	84
the course of	84
of the most	84
of the family	84
as described in	84
are involved in	83
at h post	83
it is possible	83
japanese encephalitis virus	83
h n influenza	83
was found to	83
in which the	83
in vero cells	82
compared with the	82
to that of	82
cells were incubated	82
results suggest that	82
the results showed	82
to determine whether	82
the end of	82
the viral rna	82
the immune system	82
were found to	82
added to the	81
consistent with the	81
of the human	81
in the lungs	81
vero e cells	81
avian infectious bronchitis	80
as described above	80
with or without	80
located in the	80
the control of	80
conditions of the	80
the generation of	79
found in the	79
to evaluate the	79
high levels of	79
the emergence of	79
is the first	79
the interaction between	79
results indicate that	79
sequence of the	79
in infected cells	78
the fact that	78
been reported to	78
to be the	78
the s gene	78
of the n	78
immunodeficiency virus type	78
to identify the	78
be due to	78
article is an	77
there is a	77
the creative commons	77
is an open	77
of a new	77
this article is	77
play a role	77
an open access	77
open access article	77
creative commons attribution	77
and conditions of	77
of the creative	77
under the terms	77
amino acid sequence	77
the terms and	77
access article distributed	77
the impact of	77
distributed under the	77
responsible for the	77
article distributed under	77
a and b	77
terms and conditions	77
t cells were	76
is able to	76
viral rna synthesis	76
upper respiratory tract	76
all of the	76
inhibition of the	76
that can be	76
is involved in	76
in the viral	76
understanding of the	76
of zika virus	76
as described previously	75
the pathogenesis of	75
are shown in	75
the mechanism of	75
the binding of	75
data not shown	74
cells were transfected	74
found that the	74
suggesting that the	74
that of the	74
have not been	74
to investigate the	74
was determined by	74
of the two	73
zika virus infection	73
cells were treated	73
were used for	73
was isolated from	73
associated with a	73
each of the	73
c for s	72
our understanding of	72
respiratory tract infections	72
are associated with	72
cell lysates were	72
innate immune responses	72
phylogenetic analysis of	72
binding to the	71
of the cell	71
the e protein	71
remains to be	71
than that of	71
of marburg virus	70
h n pdm	70
the function of	70
of these viruses	70
the immune response	70
the orf protein	70
the type i	70
the antiviral activity	70
virus replication in	70
a result of	69
resulting in the	69
is shown in	69
the prevalence of	69
the study of	69
amino acid sequences	69
the levels of	69
addition to the	69
an increase in	69
incubated for h	69
region of the	69
influenza virus infection	69
suggest that the	69
of the manuscript	69
wide range of	69
was carried out	69
of the genome	69
were analyzed by	68
a wide range	68
of ns a	68
is possible that	68
fetal bovine serum	68
immune responses in	68
cd and cd	68
mutations in the	68
identified in the	68
the activity of	68
and h n	68
been associated with	68
ebola virus disease	68
the respiratory tract	68
used in the	67
and immunogenicity of	67
were purchased from	67
samples were collected	67
cats with fip	67
interferon regulatory factor	67
used in this	67
of feline infectious	67
h n and	67
newcastle disease virus	67
a recent study	67
formation of the	67
is an important	67
open reading frame	67
for detection of	66
on the surface	66
likely to be	66
viral replication and	66
and in the	66
mice infected with	66
there was no	66
has been demonstrated	66
required for the	66
the combination of	65
known to be	65
contribute to the	65
when compared to	65
revealed that the	65
the spike protein	65
virus in the	65
of porcine epidemic	65
g for min	65
the time of	65
sy y cells	65
the central nervous	65
crystal structure of	65
nm in diameter	65
the ability to	65
indicated that the	65
black flying fox	65
components of the	64
are known to	64
sequences of the	64
differences in the	64
development of a	64
the evolution of	64
were able to	64
of infectious bronchitis	64
by western blot	64
t cell responses	63
a member of	63
have been described	63
were obtained from	63
cells treated with	63
it is important	63
of cd t	63
were added to	63
increase in the	62
were shown to	62
depending on the	62
some of the	62
isolated from the	62
to study the	62
the synthesis of	62
at least one	62
resulted in a	62
at the time	62
of porcine reproductive	62
is important to	62
of this study	61
the site of	61
demonstrated that the	61
which is a	61
was associated with	61
studies have shown	61
lymphocytic choriomeningitis virus	61
it is not	61
were collected from	60
be involved in	60
cellular immune responses	60
of the protein	60
of infectious virus	60
pedv n protein	60
were subjected to	60
viral rna was	60
an moi of	60
balb c mice	60
none of the	60
and incubated for	60
n and h	60
for min and	60
of the disease	60
a novel coronavirus	59
cells were seeded	59
s and s	59
in the field	59
is one of	59
dh ond pi	59
world health organization	59
the interaction of	59
infection of the	59
plays an important	59
of viral infection	59
to assess the	59
were cultured in	59
borne encephalitis virus	59
been detected in	59
mouse hepatitis virus	59
of the study	59
in this review	59
in combination with	59
in cats with	58
of west nile	58
porcine circovirus type	58
are required for	58
did not affect	58
a review of	58
in agreement with	58
of viral proteins	58
large number of	58
in a dose	57
of the three	57
is responsible for	57
to the virus	57
were determined by	57
innate and adaptive	57
rna was extracted	57
led to the	57
leading to the	57
for the development	57
indicating that the	57
the design of	57
the supernatant was	57
the severe acute	57
belonging to the	56
were positive for	56
were performed using	56
could not be	56
the most important	56
dependent on the	56
of dengue virus	56
derived from the	56
of neutralizing antibodies	56
suggested that the	56
the b protein	56
western blot analysis	56
in recent years	56
appears to be	56
of the genus	56
at the end	56
in mammalian cells	56
of feline coronavirus	56
the viral replication	56
feline leukemia virus	56
resulted in the	56
were observed in	55
in comparison to	55
to interact with	55
and cd t	55
available online at	55
these results suggest	55
at an moi	55
supplementary table s	55
the following are	55
in terms of	55
are available online	55
shown that the	55
were fixed with	55
interacts with the	55
semliki forest virus	55
following are available	55
influenza a viruses	55
the middle east	54
analysis was performed	54
a combination of	54
the virus to	54
the discovery of	54
unfolded protein response	54
in the regulation	54
this is the	54
as seen in	54
presence of the	54
the host immune	54
shown in table	54
transmissible gastroenteritis virus	53
this study was	53
in the formation	53
many of the	53
the need for	53
the result of	53
no significant difference	53
the h n	53
been reported that	53
in the cell	53
an outbreak of	53
weeks of age	53
of rift valley	53
to the cytoplasm	53
of cats with	53
the loss of	53
indicate that the	53
the virus was	52
belong to the	52
regions of the	52
airway epithelial cells	52
were found in	52
the efficacy of	52
infection in the	52
syncytial virus infection	52
of the er	52
with the same	52
included in the	52
immune responses to	52
seems to be	52
type i ifns	52
a previous study	52
in the er	52
of the coronavirus	51
in saudi arabia	51
referred to as	51
at the same	51
to the nucleus	51
from patients with	51
mediated by the	51
vero cells were	51
thought to be	51
the most common	51
or in the	51
to the cell	51
there is no	51
due to a	51
natal rgn srips	51
in the future	51
been reported in	51
their ability to	51
leads to the	51
be associated with	51
is the most	51
been shown that	51
isolated from a	51
in the nucleus	50
risk factors for	50
data indicate that	50
lead to the	50
tbk and irf	50
a role for	50
and incubated at	50
multiplicity of infection	50
there was a	50
of rna viruses	50
ebola and marburg	50
the degradation of	50
of the rna	50
are able to	50
antiviral activity against	50
the structure of	50
between the two	50
need to be	50
but not in	50
viral life cycle	50
were analyzed using	50
the ebola virus	50
and evolution of	49
study showed that	49
we did not	49
assays were performed	49
were stained with	49
to understand the	49
three times with	49
the genome of	49
this suggests that	49
is mediated by	49
the in vitro	49
online at http	49
these results indicate	49
t cells in	49
was analyzed by	49
in the design	49
a range of	48
of viral replication	48
the accumulation of	48
ebola virus infection	48
isolation of a	48
component of the	48
study of the	48
virus replication and	48
a mouse model	48
swine fever virus	48
to inhibit the	48
replication in the	48
ns a protein	48
in the brain	48
viruses have been	48
those of the	48
has been proposed	48
play an important	48
any of the	48
the same time	48
of h n	48
localization of the	48
the possibility of	47
interact with the	47
in the lung	47
regulation of the	47
there have been	47
morbidity and mortality	47
three independent experiments	47
infection in a	47
i and ii	47
adaptive immune responses	47
of the innate	47
to better understand	47
coronavirus infectious bronchitis	47
previous studies have	47
of human coronavirus	47
effect on the	47
equine encephalitis virus	47
washed three times	47
molecular characterization of	47
data suggest that	47
of the immune	47
in the human	47
for the presence	47
were significantly higher	47
viral rna in	47
low levels of	47
was able to	47
the diagnosis of	47
of the same	46
were used as	46
be used as	46
the sars coronavirus	46
comparison of the	46
specific cd t	46
acts as a	46
were performed in	46
was found in	46
in humans and	46
protein is a	46
strand rna viruses	46
the severity of	46
identification and characterization	46
also been shown	46
cells were cultured	46
open reading frames	46
simplex virus type	46
infected cells were	46
syndrome coronavirus infection	46
the n gene	46
essential for the	46
no role in	46
the viral life	46
the ratio of	46
was supported by	46
suggests that the	46
effect of the	46
genetic diversity of	45
conjugated goat anti	45
was performed to	45
of hepatitis e	45
insights into the	45
human coronavirus oc	45
is a major	45
reported to be	45
performed using the	45
obtained from the	45
were present in	45
terminal region of	45
mouth disease virus	45
a large number	45
of the recombinant	45
of the type	45
well as in	45
described in the	45
type i and	45
the decision to	45
coronavirus nucleocapsid protein	45
appear to be	45
at a concentration	45
the cytoplasm and	45
the unfolded protein	45
would like to	45
to confirm the	45
in association with	45
virus infection and	45
ebola virus glycoprotein	45
taxonomy of viruses	44
in the current	44
were washed with	44
safety and immunogenicity	44
a concentration of	44
into the cytoplasm	44
is important for	44
listed in table	44
did not show	44
had no role	44
the analysis of	44
with fetal bovine	44
nsp and nsp	44
c virus replication	44
of avian infectious	44
linked immunosorbent assay	44
cells were then	44
the occurrence of	44
were incubated at	44
the nucleocapsid protein	44
in figure b	44
it is likely	44
replication and transcription	44
from the same	44
host immune response	44
binding of the	44
followed by the	44
of the orf	44
evaluation of the	44
the concentration of	44
with acute respiratory	44
mice immunized with	44
similar to those	43
the process of	43
from cats with	43
proteins in the	43
of the spike	43
has been observed	43
is thought to	43
followed by a	43
that the virus	43
at least three	43
and function of	43
the virus in	43
green fluorescent protein	43
ns and ns	43
a series of	43
yellow fever virus	43
over the past	43
immune responses and	43
total number of	43
infected with ibv	43
is consistent with	43
the ns a	43
the spread of	43
in line with	43
cloned into the	43
writing of the	43
on the cell	43
in the study	43
domain of the	43
to examine the	43
has been suggested	43
viral replication in	43
human respiratory syncytial	43
humoral and cellular	43
s and n	43
its ability to	43
could be used	42
based on a	42
the potential for	42
to be determined	42
the influenza virus	42
for viral replication	42
of lassa fever	42
results of the	42
used as the	42
to reduce the	42
to increase the	42
reduction in the	42
the existence of	42
in southern china	42
were identified in	42
and that the	42
not required for	42
significantly higher than	42
the distribution of	42
of the influenza	42
to viral infection	42
and stored at	42
interaction with the	42
washed with pbs	42
sensitivity and specificity	42
the secretory pathway	42
been identified in	42
corresponding to the	42
and cellular immune	42
kindly provided by	42
function of the	42
results in the	42
genome sequence of	42
it is also	42
ns a and	42
was extracted from	42
the current study	42
in the development	42
due to their	41
were detected by	41
can also be	41
bovine serum albumin	41
have been found	41
is based on	41
supported by the	41
have been developed	41
in the respiratory	41
the viral envelope	41
of porcine circovirus	41
immune response in	41
respiratory tract disease	41
relative to the	41
as compared to	41
the samples were	41
of sars coronavirus	41
to play a	41
as a vaccine	41
were carried out	41
in a mouse	41
the plates were	41
for the first	41
in c cells	41
and n proteins	41
of amino acid	41
and have been	41
of the viruses	41
in accordance with	41
with the exception	41
the active site	41
venezuelan equine encephalitis	41
protein in the	41
the s and	41
viruses such as	41
the recruitment of	41
supplemented with fetal	41
respiratory tract infection	41
the origin of	40
and amino acid	40
as a consequence	40
also known as	40
considered to be	40
the causative agent	40
limit of detection	40
antiviral activities of	40
in the number	40
replication of the	40
the infection of	40
in the replication	40
that had been	40
the secretion of	40
the bone marrow	40
there are no	40
of the e	40
used to identify	40
in the decision	40
the range of	40
international committee on	40
no effect on	40
the potential of	40
that have been	40
a virus infection	40
the involvement of	40
been isolated from	40
similar to that	40
in dromedary camels	40
can lead to	40
it will be	40
and it is	40
pcr products were	39
early stages of	39
effects of the	39
e ubiquitin ligase	39
to the plasma	39
on taxonomy of	39
the infected cells	39
when compared with	39
h n virus	39
the er and	39
of human papillomavirus	39
was performed with	39
were isolated from	39
committee on taxonomy	39
the first time	39
of the first	39
the zikv natal	39
likely due to	39
coronavirus spike protein	39
its interaction with	39
binds to the	39
is dependent on	39
in the early	39
of innate immune	39
has been described	39
activity of irf	39
seen in figure	39
an inhibitor of	39
parts of the	39
of the zikv	39
with respect to	39
it was shown	38
tested positive for	38
was detected by	38
pedv and tgev	38
activity of ire	38
of patients with	38
from the er	38
in comparison with	38
i ifn signaling	38
nucleocapsid protein of	38
and adaptive immune	38
we used a	38
to the cells	38
the proportion of	38
proteins involved in	38
the frequency of	38
in some cases	38
may not be	38
primary biliary cirrhosis	38
cytokines and chemokines	38
are responsible for	38
approved by the	38
is likely that	38
the possibility that	38
ch lsc i	38
ck ch lsc	38
the exception of	38
by using the	38
higher levels of	38
surface of the	38
adaptive immune response	38
of the ifn	38
the writing of	38
of ghv g	38
compared to other	38
well plates were	38
have been detected	38
with the viral	38
in the central	38
the virus is	38
because of the	37
those in the	37
during viral infection	37
the university of	37
to generate a	37
of the four	37
are essential for	37
h k ac	37
and incubated with	37
coronavirus infections in	37
infectious peritonitis virus	37
been implicated in	37
in the writing	37
were inoculated with	37
been described in	37
in previous studies	37
which can be	37
decision to publish	37
the introduction of	37
is known to	37
are the most	37
caused by the	37
for h and	37
the international committee	37
min at room	37
and identification of	37
bind to the	37
pattern recognition receptors	37
to the er	37
to test the	37
cells were co	37
and can be	37
results indicated that	36
the influenza a	36
have demonstrated that	36
due to its	36
a lack of	36
terminal domain of	36
after h of	36
focused on the	36
been observed in	36
viruses in the	36
more likely to	36
under the control	36
of the hepatitis	36
the degree of	36
size of the	36
the cell culture	36
during the first	36
then incubated with	36
the hepatitis c	36
t cell response	36
carried out in	36
s protein of	36
stages of the	36
virus infections in	36
amino acid residues	36
assay was performed	36
a systematic review	36
in cell cultures	36
antiviral effects of	36
to those of	36
in another study	36
a significant increase	36
can be found	36
innate immune system	36
the relationship between	36
fixed with paraformaldehyde	36
h and h	36
the assembly of	36
ranging from to	36
use of the	36
genbank accession number	36
may contribute to	36
be able to	36
the onset of	36
the efficiency of	36
may be a	36
were maintained in	36
was performed as	36
of respiratory syncytial	36
nature of the	36
that do not	36
of the b	35
be related to	35
it can be	35
the potential to	35
and the cells	35
flying fox cells	35
by using a	35
transferred to a	35
in the usa	35
with and without	35
as the mean	35
incubated with the	35
the capsid protein	35
to publish the	35
and has been	35
were stored at	35
presence of a	35
is capable of	35
be found in	35
cells were lysed	35
was found that	35
was shown that	35
protein of sars	35
in the collection	35
of immune responses	35
of viral infections	35
was removed and	35
the total number	35
show that the	35
the diversity of	35
like to thank	35
degradation of the	35
interpretation of data	35
transcription and replication	35
publish the results	35
the golgi apparatus	35
a critical role	35
proteins have been	35
to analyze the	35
classical swine fever	35
at least two	35
in the us	35
the sequence of	35
in young children	35
of the total	35
are listed in	35
ond pi cells	35
viruses of the	35
results in a	35
plasmacytoid dendritic cells	35
this study were	35
samples from cats	35
we observed a	35
in hong kong	35
the rate of	35
design of the	35
control of the	35
to the control	35
in vero e	34
the republic of	34
at the indicated	34
protein and the	34
of herpes simplex	34
been used to	34
evolution of the	34
sialic acid binding	34
of the ebola	34
it should be	34
cells of the	34
and subjected to	34
m and n	34
infection in humans	34
was confirmed by	34
stat and stat	34
in healthy adults	34
the isolation of	34
to bind to	34
summarized in table	34
possible that the	34
as part of	34
in clinical trials	34
only a few	34
infected cells and	34
and marburg viruses	34
was performed by	34
the m protein	34
roles in the	34
hcq and rfifn	34
influenza d virus	34
serve as a	34
host immune responses	34
s gene mutations	34
but not the	34
republic of congo	34
for virus replication	34
identification of the	34
use of a	34
its role in	34
by centrifugation at	34
as a model	34
differences between the	34
were seeded in	34
vp and vp	34
cov s protein	34
better understand the	34
have been used	34
infected with feline	34
it was found	34
or interpretation of	34
correlated with the	33
to our knowledge	33
the s subunit	33
be detected in	33
structure and function	33
is critical for	33
rpm for min	33
the virus and	33
this indicates that	33
with that of	33
the antiviral response	33
to detect the	33
that has been	33
of the ns	33
for at least	33
some of these	33
important for the	33
influenza a and	33
the size of	33
sars and mers	33
a decrease in	33
and the other	33
positive and negative	33
protective efficacy of	33
has been used	33
is supported by	33
be noted that	33
should be noted	33
transfected with the	33
b and c	33
endoplasmic reticulum stress	33
viral rna replication	33
be important for	33
cells transfected with	33
did not have	33
high level of	33
with feline immunodeficiency	33
is necessary for	33
new england biolabs	33
virus infection of	33
it is well	33
were incubated for	33
the association of	33
prior to the	33
viral rna and	33
were collected and	33
in cells infected	33
are capable of	33
treated with the	33
reported that the	33
was incubated with	33
of the samples	33
neutralizing antibodies against	33
transmission electron microscopy	33
in both the	33
virus replication by	33
infectious cdna clone	33
entry into the	33
sequencing of the	33
shown to inhibit	33
serum samples were	32
in viral replication	32
rna polymerase ii	32
during the course	32
needs to be	32
to the sars	32
increased expression of	32
of which are	32
proteins of the	32
also been reported	32
resulting in a	32
and then incubated	32
west african bagv	32
total rna was	32
as in the	32
experimental infection of	32
a subset of	32
been found to	32
the beginning of	32
and infected with	32
the complete genome	32
vaccinated challenged birds	32
tumor necrosis factor	32
syndrome coronavirus in	32
in table s	32
t cells and	32
of human immunodeficiency	32
used to detect	32
avian influenza virus	32
is composed of	32
out of the	32
higher than those	32
detected in a	32
a h n	32
of the c	32
broad range of	32
induced by the	32
of lassa virus	32
as a negative	32
of the antiviral	32
contrast to the	32
to the development	32
cell culture supernatants	32
a key role	32
plays a role	32
was performed on	32
the dynamics of	32
linked to the	32
complete genome sequence	32
of a human	32
human papillomavirus type	32
figure s a	32
of the novel	32
immunized via the	32
causative agent of	32
antiviral effect of	32
to investigate whether	32
human and animal	32
production of infectious	32
mechanism of action	32
is likely to	32
it would be	31
by means of	31
not detected in	31
as a control	31
room temperature for	31
and activation of	31
along with the	31
can be detected	31
that they are	31
the kinetics of	31
of the replication	31
detection of the	31
the limit of	31
of l vdna	31
in case of	31
h at room	31
sequence of a	31
years of age	31
infection in mice	31
result in the	31
viral and host	31
spike protein of	31
together with the	31
at the cell	31
supported by a	31
to compare the	31
e and e	31
be explained by	31
complete genome sequences	31
with severe acute	31
depends on the	31
to be an	31
of interferon regulatory	31
funders had no	31
to generate the	31
is sufficient to	31
led to a	31
experiments were performed	31
to be involved	31
these data indicate	31
receptor for the	31
the interaction with	31
processing of the	31
in the n	31
which is the	31
was performed in	31
rna and dna	31
may also be	31
by flow cytometry	31
and of the	31
in viral rna	31
the most abundant	31
yet to be	31
change in the	31
the outcome of	31
the past decade	31
interfere with the	31
to the viral	31
virus nonstructural protein	31
the funders had	31
the influence of	31
that there is	30
experimentally infected with	30
infected dh cells	30
of infection in	30
used as an	30
have been isolated	30
used to determine	30
response to infection	30
replication in vitro	30
collected from the	30
was obtained from	30
are grateful to	30
genomic characterization of	30
the nature of	30
reported in the	30
the pathogenicity of	30
the human population	30
acute respiratory distress	30
steps of the	30
of the cells	30
and pathogenesis of	30
for treatment of	30
plp dub activity	30
residues in the	30
of the virion	30
binding domain of	30
and in vitro	30
the entry of	30
in a cells	30
infection has been	30
immune responses against	30
virus and the	30
to have a	30
is characterized by	30
the replicative structures	30
the zika virus	30
of the full	30
the presence or	30
in hek t	30
cells per well	30
has been identified	30
n protein is	30
patients infected with	30
expression of a	30
serial dilutions of	30
we used the	30
compared to wt	30
is crucial for	30
extracted from the	30
or absence of	30
not affect the	30
integrity of the	30
able to induce	30
on viral replication	30
higher than that	30
we demonstrated that	30
course of infection	30
washed twice with	30
pandemic influenza a	30
upper and lower	30
difference in the	30
the localization of	30
are susceptible to	29
for h with	29
to determine if	29
pcr assay for	29
may have been	29
ion channel activity	29
democratic republic of	29
studies on the	29
the appearance of	29
has recently been	29
protein of the	29
were susceptible to	29
key role in	29
was identified as	29
amino acids in	29
for s and	29
consistent with previous	29
these data suggest	29
has been found	29
and mortality in	29
natal rgn replicon	29
the first report	29
is also a	29
significant difference in	29
nucleotide sequences of	29
clinical features of	29
or rb c	29
the f protein	29
has been associated	29
compared to those	29
with a high	29
to the presence	29
isolation and characterization	29
majority of the	29
dna and rna	29
to the same	29
license the authors	29
canine distemper virus	29
the suppression of	29
around the world	29
presence or absence	29
in the first	29
a negative control	29
the transmission of	29
review of the	29
be required to	29
and lower respiratory	29
decrease in the	29
supplemented with fbs	29
respiratory disease in	29
and control of	29
of n protein	29
result of the	29
was replaced with	29
we show that	29
in the infected	29
the transport of	29
of action of	29
mice immunized via	29
innate immunity and	29
associated with an	29
of viral particles	29
times with pbs	29
expression in the	29
using graphpad prism	29
h post transfection	29
into the host	29
which have been	29
compared to mock	29
as determined by	29
is necessary to	29
to form the	29
of west african	29
the basis of	29
is similar to	29
host and viral	29
associated with severe	29
as a potential	29
the structural proteins	29
of a viral	29
african bagv isolates	29
the sites of	29
to each other	29
the mechanisms of	29
which has been	28
in figure c	28
immunodeficiency virus infection	28
characteristics of the	28
disruption of the	28
leading to a	28
one or more	28
for vaccine development	28
viral genomic rna	28
of these two	28
by the host	28
influenza virus hemagglutinin	28
there has been	28
was measured by	28
is not required	28
that could be	28
and release of	28
in mice and	28
of antibodies against	28
in host cells	28
the recombinant viruses	28
respiratory distress syndrome	28
in the virus	28
cells and the	28
mapped to the	28
inhibition of viral	28
were compared to	28
were used in	28
by the addition	28
was significantly higher	28
neutrophils and monocytes	28
in the uk	28
correlation between the	28
analyses were performed	28
in the blood	28
the nlrp inflammasome	28
in animal models	28
magnetic bead rna	28
in the spleen	28
a significant reduction	28
are critical for	28
in the induction	28
transmission of the	28
cleavage of the	28
assembly of the	28
the cause of	28
the in ovo	28
to be important	28
are presented as	28
been identified as	28
amino acid identity	28
hemorrhagic fever virus	28
of the central	28
mechanism by which	28
that there was	28
the depletion of	28
mhc class i	28
of extracellular vesicles	28
identified as a	28
accordance with the	28
recent advances in	28
major histocompatibility complex	28
been found in	28
and phylogenetic analysis	28
were performed with	28
via the tc	28
the stability of	28
at different time	28
amino acid changes	28
similar results were	28
infected with a	28
the integrity of	28
immune response against	28
be responsible for	28
by plaque assay	28
virus entry into	28
lassa fever in	28
on the s	28
belongs to the	28
to interfere with	28
the mutant virus	28
insight into the	28
is not clear	28
cells were grown	28
marburg hemorrhagic fever	28
have been associated	28
activity in vitro	28
results demonstrated that	28
of the world	28
cell lines were	28
the most commonly	28
pnt and mnt	28
immune response and	28
in cultured cells	28
infection of human	28
it is a	28
we sought to	27
in the past	27
with an anti	27
of the interferon	27
compared to non	27
of the epidemic	27
proteolytic processing of	27
attachment and entry	27
viral gene expression	27
of the membrane	27
identified in this	27
high prevalence of	27
the novel coronavirus	27
with the host	27
were grown in	27
the viral protein	27
is a highly	27
to form a	27
cell lines and	27
by western blotting	27
of tbk and	27
is the only	27
the adaptive immune	27
hstat ki mice	27
that in the	27
infected with mers	27
coronavirus infection in	27
are needed to	27
studies have demonstrated	27
genetic characterization of	27
at the plasma	27
transcriptional activity of	27
of a virus	27
of virus replication	27
the host cells	27
could be observed	27
of novel coronavirus	27
for up to	27
the medium was	27
were included in	27
antiviral activity in	27
than those in	27
of host cell	27
the antiviral effects	27
to a lesser	27
may play a	27
evidence for the	27
results show that	27
dmem supplemented with	27
the age of	27
contributes to the	27
and analysis of	27
as a positive	27
i ifn response	27
of the cellular	27
in the range	27
of cd and	27
two of the	27
n influenza virus	27
in the late	27
responses in mice	27
cov and mers	27
the safety and	27
of zikv natal	27
are required to	27
is a member	27
cells compared to	27
of the different	27
for the generation	27
with the highest	27
of a large	27
wide variety of	27
there is evidence	27
which in turn	27
the upper respiratory	27
many of these	27
act as a	27
type i interferons	27
the mice immunized	27
which may be	27
and found that	27
an overview of	27
interaction of the	27
comparative analysis of	27
and stained with	27
for the diagnosis	27
it has also	27
shown in the	27
at a moi	27
were collected at	27
to explore the	27
increased risk of	27
a lesser extent	27
a reduction in	27
viral infection and	27
a positive control	27
of a recombinant	27
in this regard	27
by interfering with	27
patients with severe	27
was reported to	27
the immunogenicity of	27
for the study	27
in the last	27
plates were incubated	27
tlr and tlr	26
better understanding of	26
the length of	26
avian coronavirus infectious	26
is required to	26
an in vitro	26
in the pathogenesis	26
in the americas	26
amino acid level	26
the cleavage of	26
were identified as	26
may lead to	26
in this context	26
systematic review and	26
were expressed as	26
to the host	26
human coronavirus e	26
been proposed that	26
analysis showed that	26
and development of	26
with pbs and	26
was also observed	26
expression levels of	26
activated protein kinase	26
of the autophagy	26
with the indicated	26
basis for the	26
critical for the	26
used to treat	26
compared with those	26
in any of	26
rna synthesis and	26
the gfp gene	26
at days post	26
dendritic cells and	26
gene expression in	26
of eef a	26
seem to be	26
a consequence of	26
the mixture was	26
a broad range	26
it may be	26
expression of nsp	26
of the infection	26
neutralizing antibody titers	26
cells were harvested	26
supplementary figure s	26
by the presence	26
different from the	26
i interferon response	26
interaction between the	26
sense rna viruses	26
in the two	26
in this region	26
la and aa	26
risk factor for	26
viral infection in	26
induction of the	26
of cells with	26
is known about	26
complete protection against	26
mouse model of	26
be used for	26
of the p	26
cov infection in	26
inhibitors of the	26
recruited to the	26
the location of	26
significant increase in	26
could also be	26
bars represent the	26
emerging infectious diseases	26
virus in a	26
could be a	26
equine arteritis virus	26
supernatants were collected	26
of amino acids	26
infection in vitro	26
a multiplicity of	26
for the expression	26
clinical signs of	26
conformational changes in	26
had no effect	26
i and mda	26
shown to have	26
spread of the	26
well as a	26
for h in	26
virus life cycle	26
different concentrations of	26
not result in	26
the human immunodeficiency	26
and do not	26
host innate immune	26
added to each	26
of a single	26
more than one	26
replication and pathogenesis	26
of the hiv	26
has been detected	26
encoded by the	26
disease control and	26
a moi of	26
acute respiratory tract	26
of human metapneumovirus	26
are thought to	26
tbk or irf	26
the world health	26
well plates and	26
the er membrane	26
to the human	26
virus was detected	26
in the genus	26
virus isolated from	26
the z protein	26
presented as the	25
high degree of	25
for ebola virus	25
by targeting the	25
of rabies virus	25
was detected using	25
agreement with the	25
the roles of	25
of the other	25
with an increased	25
of the capsid	25
virus from the	25
orf and orf	25
used to generate	25
of natural products	25
was defined as	25
different time points	25
on the viral	25
been demonstrated to	25
in virus replication	25
have been observed	25
and transmission of	25
we are grateful	25
determined by the	25
there were no	25
for use in	25
each other and	25
the early stages	25
a wide variety	25
from the endoplasmic	25
in the production	25
inhibitory effect of	25
is not known	25
that it is	25
in the host	25
reactive oxygen species	25
the antiviral effect	25
i interferon signaling	25
and replication of	25
on the basis	25
were washed three	25
weight loss and	25
the cell lysates	25
were tested for	25
with the virus	25
each of these	25
titers were determined	25
features of the	25
of the l	25
analysis revealed that	25
control and prevention	25
genome sequences of	25
detection of a	25
implications for the	25
carried out using	25
a family of	25
of an outbreak	25
in nonhuman primates	25
a receptor for	25
bound to the	25
to this end	25
of lymphocytic choriomeningitis	25
in this case	25
a high level	25
gene expression and	25
in the family	25
we evaluated the	25
the transcriptional activity	25
appeared to be	25
analysis of a	25
all of them	25
does not affect	25
of nipah virus	25
of the ha	25
of the complete	25
within the same	25
virus infection by	25
republic of the	25
properties of the	25
functions of the	25
i and type	25
genes involved in	25
virus as a	25
a highly conserved	25
fcov type and	25
in the control	25
disease in humans	25
were pretreated with	25
of the infected	25
error bars represent	25
the in vivo	25
m and m	25
to test this	25
the membrane was	25
development of the	25
of vaccinia virus	25
into the nucleus	25
cell entry of	25
in pregnant women	25
have been proposed	25
determination of the	25
viruses and their	25
the most potent	25
at the nucleotide	25
are important for	25
cov n protein	25
to sites of	25
of japanese encephalitis	25
histone h acetylation	25
and ns b	25
c virus infection	25
of infectious diseases	24
expressed in the	24
released into the	24
amino acid change	24
study was to	24
in the cells	24
site of the	24
inoculum was removed	24
was measured using	24
of three independent	24
the negative control	24
there are several	24
we measured the	24
inhibitory effects of	24
inhibitory activity of	24
orders of magnitude	24
the observation that	24
serves as a	24
at a multiplicity	24
is due to	24
of the gp	24
assessment of the	24
virus titers were	24
to the s	24
sensitivity of the	24
viral infections in	24
dengue virus infection	24
this is a	24
in more detail	24
with poly i	24
the endocytic pathway	24
was no significant	24
perk signaling pathway	24
in the rhbm	24
were harvested and	24
electron microscopy of	24
in the sars	24
and expression of	24
peripheral blood mononuclear	24
the lungs of	24
is caused by	24
to test whether	24
of innate immunity	24
the rest of	24
emerging and re	24
also showed that	24
vaccines have been	24
implicated in the	24
indicated by the	24
expression of cd	24
the abundance of	24
of the congo	24
especially in the	24
is present in	24
in insect cells	24
was applied to	24
of mers coronavirus	24
could be due	24
associated molecular patterns	24
borne zoonotic dis	24
infected c cells	24
caused by a	24
novel coronavirus from	24
we would like	24
transfected packaging cells	24
into the cytosol	24
the performance of	24
innate lymphoid cells	24
are shown as	24
the nucleus and	24
neutralizing antibodies in	24
in the cns	24
serum samples from	24
been linked to	24
not yet been	24
nucleotide and amino	24
vg plus poly	24
isa vg plus	24
knowledge of the	24
the infected cell	24
host immune system	24
in the c	24
a set of	24
than those of	24
infection with a	24
but it is	24
human coronavirus nl	24
of this protein	24
the th day	24
most closely related	24
to each well	24
in dh ond	24
shown to induce	24
blood mononuclear cells	24
are summarized in	24
expression level of	24
increasing concentrations of	24
the construction of	24
antiviral innate immunity	24
independent of the	24
in the mouse	24
the genomes of	24
critical role in	24
the family of	23
molecular evolutionary genetics	23
resulted in an	23
fusion of the	23
in the upper	23
not significantly different	23
be present in	23
discovery of a	23
as a novel	23
findings suggest that	23
and viral rna	23
positively selected sites	23
of cell surface	23
standard error of	23
modulation of the	23
of equine coronavirus	23
to the formation	23
although it is	23
the tc route	23
production of the	23
influenza virus a	23
mrna levels of	23
at least in	23
ebola hemorrhagic fever	23
it is worth	23
based on their	23
of irf and	23
further studies are	23
the two viruses	23
half of the	23
in the transmission	23
in the bone	23
species in the	23
and dengue virus	23
the type of	23
of infection and	23
at rpm for	23
protective immunity against	23
been proposed to	23
infectious bronchitis viruses	23
cdna clone of	23
in south korea	23
of the new	23
to the reference	23
stages of infection	23
only in the	23
expression of ifn	23
days post infection	23
with those of	23
response to the	23
the susceptibility of	23
in the activation	23
to measure the	23
the percentages of	23
infection results in	23
mutation in the	23
are found in	23
in the non	23
od value of	23
been suggested that	23
nuclei were stained	23
length of the	23
from infected cells	23
in the mice	23
plates were washed	23
efficacy of a	23
u ml penicillin	23
to characterize the	23
as shown by	23
viral proteins in	23
in the trachea	23
of the h	23
infection and the	23
are present in	23
essential for virus	23
the reduction of	23
viral proteins and	23
no significant differences	23
disease in the	23
located at the	23
signs of disease	23
close to the	23
little is known	23
were determined using	23
rna viruses that	23
associated with acute	23
provided by dr	23
and the virus	23
is difficult to	23
this work was	23
the backbone of	23
importance of the	23
was analyzed using	23
in balb c	23
syncytial virus in	23
coronavirus associated with	23
e virus infection	23
was the most	23
seen in the	23
the dub activity	23
vector borne zoonotic	23
important roles in	23
cell culture and	23
was purchased from	23
human airway epithelial	23
of the mean	23
efficacy of the	23
feline enteric coronavirus	23
double membrane vesicles	23
small number of	23
at h p	23
the nucleotide level	23
by binding to	23
infection with the	23
and cloned into	23
with a single	23
levels of the	23
virus interacting proteins	23
reservoir hosts of	23
in the nasal	23
of viruses in	23
be attributed to	23
the life cycle	23
association of the	23
detection of fcov	23
for disease control	23
no evidence of	23
were fixed and	23
of windowed averages	23
explained by the	23
humoral immune response	23
and the viral	23
in this process	23
the application of	23
a and ns	23
virus disease in	23
it was not	23
immunogenicity of the	23
acid sequences of	23
evolutionary genetics analysis	23
infected a cells	23
and used to	23
influenza virus in	23
the infectivity of	23
are likely to	23
is not a	23
defined as the	23
in a similar	23
at day post	22
bead rna extraction	22
in conjunction with	22
the supernatants of	22
and ns a	22
of mice with	22
in bats in	22
structural and functional	22
part of a	22
virus has been	22
information on the	22
their role in	22
in this work	22
and to the	22
effects on the	22
of the flavivirus	22
functional receptor for	22
in the republic	22
h n viruses	22
using the same	22
also been described	22
as it is	22
min at rt	22
of rsv infection	22
was not observed	22
final concentration of	22
mechanisms of action	22
into host cells	22
the increase of	22
influenza a h	22
been reported for	22
of infection by	22
not been reported	22
of the vaccine	22
be interesting to	22
the supernatants were	22
in hepatitis c	22
which leads to	22
the evaluation of	22
the quality of	22
the basis for	22
included in this	22
is regulated by	22
the phosphorylation of	22
acid sequence of	22
there is little	22
were measured by	22
the lower respiratory	22
with pneumonia in	22
windowed averages for	22
in vivo and	22
did not observe	22
incubated overnight at	22
copy numbers of	22
the ecology of	22
of mouse hepatitis	22
used to evaluate	22
the sensitivity of	22
genogroup i strains	22
the selection of	22
summary of windowed	22
has to be	22
of the small	22
synthesis of the	22
to the best	22
the epidemiology of	22
in west africa	22
can result in	22
activation of caspase	22
in complex with	22
pandemic h n	22
has shown that	22
conflicts of interest	22
was extracted using	22
was not detected	22
in this way	22
we determined the	22
detection of feline	22
from the cell	22
evidence of a	22
of these proteins	22
cells were maintained	22
were then incubated	22
n genes of	22
of the m	22
levels of viral	22
the aim of	22
induction of ifn	22
prevention and control	22
is needed to	22
by interacting with	22
a proportion of	22
except for the	22
has been a	22
of the golgi	22
the difference in	22
stability of the	22
mediated inhibition of	22
of at least	22
to block the	22
of hr p	22
protein of porcine	22
regardless of the	22
a study of	22
patients with acute	22
we showed that	22
of the major	22
stranded rna viruses	22
to virus infection	22
to the genus	22
in a single	22
as a loading	22
formation of a	22
cells were collected	22
may be due	22
we examined the	22
proteins that are	22
interactions with the	22
with each other	22
we analyzed the	22
formed by the	22
the increase in	22
version of the	22
to the family	22
only a small	22
is independent of	22
epithelial cells and	22
statistical analyses were	22
rest of the	22
not able to	22
to the cytosol	22
ability to induce	22
a loading control	22
live attenuated vaccines	22
a panel of	22
we investigated the	22
strand rna virus	22
sites of the	22
the cmv promoter	22
a better understanding	22
each sample was	22
transmissible gastroenteritis coronavirus	22
in north america	22
followed by cycles	22
the parental virus	22
in the feces	22
molecular epidemiology of	22
humans and animals	22
cats infected with	22
was identified in	22
antibody response to	21
minor capsid protein	21
to rsv infection	21
an essential role	21
in mosquito cells	21
and treatment of	21
cells were stained	21
we compared the	21
in the liver	21
the viral infection	21
the transcription factor	21
most of these	21
viruses can be	21
been suggested to	21
the relevance of	21
the t cell	21
terminus of the	21
cellular receptor for	21
for the formation	21
virus was isolated	21
compared to a	21
virus entry and	21
role in viral	21
in rhesus macaques	21
of the cd	21
infections in children	21
as one of	21
by electron microscopy	21
for h before	21
of human respiratory	21
the west african	21
to facilitate the	21
against ebola virus	21
at and dpi	21
in the population	21
is a functional	21
of the mutant	21
absence of the	21
in living cells	21
was sufficient to	21
type and type	21
sites of viral	21
a comparison of	21
this was not	21
protein levels of	21
replication and assembly	21
several studies have	21
fever virus in	21
or infected with	21
direct rna sequencing	21
human monoclonal antibody	21
african green monkey	21
all samples were	21
in tissue culture	21
of wdnhbe cells	21
in china and	21
by cycles of	21
specificity of the	21
origin of the	21
a major role	21
it was also	21
to infection with	21
the perk inhibitor	21
induction of apoptosis	21
data were analyzed	21
cov and sars	21
was consistent with	21
of zikv infection	21
in support of	21
reduction in viral	21
in the previous	21
in the middle	21
inhibitor of the	21
ibv infected cells	21
the incubation period	21
de novo assembly	21
from the plasma	21
ectopic expression of	21
the expression level	21
fold increase in	21
the form of	21
studies of the	21
does not require	21
the cells and	21
in the treatment	21
performed as previously	21
the virus life	21
rna extracted from	21
of this virus	21
is a novel	21
influenza h n	21
the brains of	21
a functional receptor	21
the viral proteins	21
induced type i	21
tract infections in	21
to improve the	21
also found in	21
rna was detected	21
after infection with	21
development of vaccines	21
that expression of	21
in south africa	21
the sialic acid	21
by incubation with	21
fcov type s	21
the phylogenetic trees	21
the lassa virus	21
the probability of	21
rna in the	21
ffv and felv	21
with b c	21
of the nucleocapsid	21
virus with a	21
and h post	21
internal ribosome entry	21
cell surface hs	21
association with the	21
nucleic acid extraction	21
from three independent	21
depend on the	21
amino acid substitution	21
is the main	21
translation initiation factor	21
it is the	21
indicates that the	21
in vitro studies	21
the dengue virus	21
with regard to	21
response in the	21
the inhibitory effect	21
were washed twice	21
to obtain a	21
the previous study	21
has previously been	21