trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
as well as	1536
the presence of	1460
the expression of	1311
in patients with	1210
the development of	934
the role of	914
in this study	816
in the presence	808
the effect of	775
in response to	752
role in the	725
the effects of	693
tumor necrosis factor	654
study was to	643
the pathogenesis of	638
been shown to	630
of this study	624
the aim of	618
is associated with	607
the production of	548
in the pathogenesis	547
cd t cells	543
in order to	540
has been shown	536
the treatment of	526
one of the	516
the present study	514
this study was	510
to investigate the	505
involved in the	502
compared to the	475
an important role	470
the activation of	447
the use of	445
the induction of	428
of patients with	426
important role in	405
we found that	402
aim of this	397
found to be	393
results suggest that	386
the number of	376
a role in	361
the formation of	354
was found to	353
it has been	350
cd and cd	349
due to the	348
a number of	343
an increase in	337
there was no	333
the absence of	332
in addition to	330
activation of the	327
blood mononuclear cells	320
was used to	317
by flow cytometry	315
to evaluate the	313
expression of the	312
the release of	311
part of the	308
tumour necrosis factor	305
materials and methods	301
according to the	299
play an important	298
the majority of	298
be involved in	295
the regulation of	292
well as the	288
were treated with	287
peripheral blood mononuclear	285
cells in the	285
of the patients	283
shown to be	282
we investigated the	278
to determine the	278
increase in the	278
used as a	277
appears to be	276
the immune system	275
the innate immune	274
results indicate that	274
as compared to	271
in the lung	269
the importance of	261
on the other	260
t cells in	258
the control group	257
for the treatment	257
associated with a	255
play a role	254
in the treatment	253
in the absence	251
the level of	250
differences in the	250
contribute to the	249
a variety of	248
has been reported	246
was associated with	243
based on the	241
we conclude that	240
have shown that	240
as a result	240
are involved in	239
the immune response	237
the ability of	235
to be a	235
associated with the	232
in contrast to	232
svegf and svegfr	231
the levels of	231
from patients with	227
with and without	226
to study the	225
in the control	224
we show that	223
was measured by	222
innate immune system	220
of the immune	220
there is a	218
in the present	215
the frequency of	215
the other hand	214
were detected in	214
increased levels of	213
was used as	211
in peripheral blood	208
the onset of	208
there was a	207
in the development	207
was determined by	207
blood samples were	207
the inflammatory response	207
be associated with	206
the group of	205
data suggest that	204
production of il	204
a result of	203
present study was	203
levels of il	200
the severity of	197
and in the	197
well as in	197
is an important	197
the risk of	195
to play a	192
of the innate	191
to examine the	190
the concentration of	190
the activity of	189
the influence of	186
of the inflammatory	186
we are currently	185
the results of	185
showed that the	185
high levels of	184
aim of the	184
in vitro and	184
cd t cell	183
herpes simplex virus	183
significant increase in	183
a decrease in	182
of the present	181
cells of the	180
patients with severe	180
this study is	180
before and after	180
the association between	179
acute lung injury	178
to be involved	178
the ability to	177
was observed in	176
resulted in a	176
suggest that the	176
to assess the	175
of the disease	175
will be presented	174
were determined by	173
in the group	173
our results suggest	173
expression of cd	173
than in the	173
the oral mucosa	172
is characterized by	172
vitamin c supplementation	171
a role for	170
when compared to	170
mbl levels and	170
t cells were	170
lactic acid bacteria	169
activity of the	168
been found to	168
of nk cells	168
found in the	168
central nervous system	167
been reported to	167
genes involved in	167
is involved in	167
the lectin pathway	167
may be a	166
release of svegf	165
cytokines such as	165
these results indicate	165
between malaria and	165
were able to	165
analysis of the	164
is one of	164
the binding of	163
significantly higher in	163
in the regulation	163
of dendritic cells	162
of t cells	162
results showed that	162
responsible for the	161
the incidence of	161
the generation of	161
we have shown	161
are associated with	161
a critical role	160
members of the	160
the addition of	160
is dependent on	160
has been demonstrated	159
a significant increase	159
a total of	158
changes in the	158
were significantly higher	158
these results suggest	158
respiratory distress syndrome	157
in the study	157
we have previously	157
serum levels of	156
reported to be	156
reactive oxygen species	156
may contribute to	156
for the development	156
a pivotal role	155
of the study	155
a combination of	155
t cells and	154
was significantly higher	154
was to investigate	154
in terms of	153
is the first	153
were isolated from	153
were determined in	151
the capacity of	151
pivotal role in	150
can be used	150
the time of	150
indicate that the	150
the fact that	150
there were no	149
as in the	149
the lack of	149
of the most	149
study is to	148
t cells from	148
found that the	147
in combination with	147
such as the	147
we demonstrated that	147
samples were collected	146
the most common	146
in both groups	146
higher in the	146
was found in	146
have demonstrated that	146
are capable of	145
to determine whether	145
to be the	145
critical role in	145
present in the	145
observed in the	145
the hypothesis that	145
response to the	145
the degree of	144
be used to	144
the end of	143
increased in the	143
of complement activation	143
with or without	142
seems to be	142
in these patients	142
innate and adaptive	141
at the same	141
were used to	141
were stimulated with	140
were incubated with	140
the secretion of	139
we studied the	139
have been shown	139
in this project	139
compared to corresponding	138
to identify the	138
compared to healthy	138
of the protein	138
of the two	138
and in vivo	138
iga protease activity	137
human collectins in	137
supported by the	137
the amount of	137
detected in the	136
factor h binding	136
to corresponding hc	136
responses in the	136
were found to	136
associated with increased	136
compared to controls	136
may play a	136
alternatively activated macrophages	136
and healthy controls	136
compared to control	135
a mouse model	135
the response to	135
were observed in	135
vitro and in	135
like domain of	134
we hypothesized that	134
the function of	133
the course of	133
was assessed by	133
mouse model of	133
related to the	133
was evaluated by	133
inflammatory bowel disease	133
increased expression of	132
association between malaria	132
of svegf and	132
sentinel lymph nodes	132
severe acute respiratory	132
endothelial growth factor	131
nitric oxide synthase	131
of the human	131
used in the	131
is the most	130
plays an important	130
vascular endothelial growth	130
has not been	130
the relationship between	130
were measured by	130
a and il	130
c and c	130
the basis of	130
the design of	129
was to evaluate	129
their ability to	129
is produced by	129
was carried out	128
cells in vitro	128
but not in	128
transforming growth factor	128
to increase the	127
of nitric oxide	127
is known to	126
critically ill patients	126
been associated with	126
has also been	126
role of the	125
there is no	125
majority of the	125
most of the	125
with respect to	125
in a dose	125
findings indicate that	125
its ability to	124
intensive care unit	124
was shown to	124
have not been	124
of inflammatory cytokines	124
be detected in	124
results demonstrate that	124
acute respiratory syndrome	123
the increase in	123
compared with the	123
patients with acute	123
the frequencies of	123
patients compared to	123
the study was	122
at the time	122
we examined the	122
such as il	122
in our study	122
have been used	122
is a major	121
systemic lupus erythematosus	121
regulation of the	121
isolated from the	121
in women with	121
in the first	121
in vitro stimulation	121
and activation of	121
the identification of	121
on the basis	120
in vivo and	120
cells and the	120
in the activation	120
the same time	120
were found in	119
for the first	119
any of the	118
the cells were	118
because of the	118
the purpose of	117
necrosis factor alpha	117
are known to	117
expression of human	117
cells were treated	117
associated with an	117
of the gut	116
t cells that	116
are currently investigating	116
of cell death	116
is able to	116
of vitamin e	116
such as tnf	116
our results indicate	116
healthy blood donors	115
cells were found	115
shown that the	115
added to the	115
the complement system	115
acute respiratory distress	115
for up to	114
the site of	114
the form of	114
effect on the	114
and can be	114
were included in	114
we aimed to	114
surface expression of	114
was not altered	114
regulatory t cells	114
been shown that	113
is mediated by	113
have been found	113
have been reported	113
levels of tnf	113
the central nervous	113
only in the	113
be used for	113
is induced by	113
findings suggest that	113
we have investigated	113
cellular immune responses	113
we observed that	112
cell responses in	112
in children with	112
was to determine	112
increased risk of	112
which in turn	111
the cellular immune	111
of the pro	111
and dendritic cells	111
been demonstrated in	111
depending on the	111
t cell activation	111
is likely to	110
a key role	110
stimulation with il	110
in the early	110
gene expression in	109
human peripheral blood	109
the plasma membrane	109
did not induce	109
serve as a	109
mice immunized with	108
higher levels of	108
in the human	108
in the form	108
has been used	108
the kinetics of	108
of bronchial asthma	108
activation of complement	108
the action of	107
effects on the	107
the sera of	107
the amino acid	107
the first time	107
significantly increased in	107
in the horse	107
the impact of	107
we have demonstrated	106
investigate the role	106
no difference in	106
dependent on the	106
in the sera	106
be related to	106
plasma levels of	106
it was found	106
antibodies were detected	105
leads to the	105
balb c mice	105
and cd t	105
a a receptor	105
cell proliferation and	105
lymph nodes were	105
of the cell	105
presented at the	105
known to be	105
to test the	105
we have recently	104
levels in the	104
the management of	104
we have developed	104
the inhibition of	104
th and th	104
be presented at	104
and adaptive immunity	104
special emphasis on	104
resulting in the	104
of tumor necrosis	104
implicated in the	104
was detected in	103
in the expression	103
the capacity to	103
effect of the	103
in presence of	103
in the liver	103
in exon and	103
have been described	103
of factor h	103
of human collectins	103
expression of cla	103
multiple organ failure	103
analysis was performed	103
proliferating cells were	102
prevalence of h	102
pathway of complement	102
ms from sassari	102
lxrs and their	102
iga antibody to	102
of der p	102
western blot analysis	102
were obtained from	102
the factor h	102
of iga protease	102
cancer cell line	102
with special emphasis	102
ms from stockholm	102
mala s for	102
antibody to type	102
h after elicitation	102
the goal of	102
collectins in normal	102
asthma and allergic	102
in comparison to	102
group of divers	102
is required for	102
for factor h	102
these results demonstrate	101
was supported by	101
be due to	101
of the il	101
b and hla	101
no significant difference	101
is due to	101
cytokine tumour necrosis	101
a series of	101
of the gene	101
mbl levels were	101
the results showed	101
were similar in	101
is expressed in	101
in cd b	101
antiviral and immunomodulatory	100
play a key	100
global proteome analysis	100
the rate of	100
lectin pathway of	100
the results will	100
the context of	100
could be used	100
by means of	100
in the mouse	100
studies have shown	100
and expression of	99
complement activation through	99
a set of	99
malaria and malnutrition	99
obstetrics and gynecology	99
patients with a	99
the nk cells	99
mmgl and mmgl	99
results in the	99
is not a	99
included in the	99
bacteria lactobacillus acidophilus	99
this study we	99
development of the	99
capacity of ae	99
leading to the	99
key role in	98
was performed using	98
production of tnf	98
the control of	98
the mechanism of	98
similar to the	98
in breast cancer	97
at the end	97
the transcription factor	97
was not observed	97
play a pivotal	97
cells were isolated	97
a central role	97
cancer cell lines	97
amino acid residues	97
polymorphisms in the	97
we showed that	97
understanding of the	97
no effect on	97
of proinflammatory cytokines	96
of cd t	96
diseases such as	96
mediated by the	96
may be involved	96
of cd and	96
the objective of	96
indicated that the	96
the most important	96
is thought to	96
immune response against	95
the synthesis of	95
in the context	95
likely to be	95
could be detected	95
patients with sepsis	95
was found that	95
role for the	94
innate immune response	94
a major role	94
from healthy donors	94
in the brain	94
smooth muscle cells	94
not associated with	94
the patients were	94
to this end	94
the balance between	94
a reduction in	94
in the induction	94
of genes involved	94
of the cellular	94
were higher in	94
protective effect of	93
not due to	93
group of patients	93
for treatment of	93
data indicate that	93
t cells was	93
appeared to be	93
we suggest that	93
a period of	92
the administration of	92
white blood cells	92
activation of macrophages	92
been implicated in	92
of macrophages and	92
release of the	92
may lead to	92
may be associated	92
mhc class ii	92
we propose that	92
this suggests that	92
to understand the	92
during the first	92
to bind to	92
was reduced in	92
t cells are	92
been used for	91
an attempt to	91
in the same	91
these data suggest	91
which may be	91
in the rat	91
of the cd	91
central role in	91
in association with	91
in some cases	91
the efficacy of	91
natural killer cell	91
single nucleotide polymorphisms	91
cells were incubated	90
activated protein kinase	90
major role in	90
a history of	90
expression of il	90
presence of a	90
significantly associated with	90
and compared to	90
the control and	90
and endothelial cells	90
clinical signs of	90
for the presence	90
the prevalence of	90
appear to be	90
showed a significant	90
by western blot	90
is responsible for	89
have to be	89
as demonstrated by	89
is part of	89
influenza a virus	89
in which the	89
the diagnosis of	89
have developed a	89
that there is	89
levels were measured	89
in the patients	89
the analysis of	89
in out of	89
systemic inflammatory response	89
by western blotting	89
the involvement of	89
in an attempt	89
the cell surface	89
difference between the	89
the molecular mechanisms	89
is supported by	88
levels of the	88
was used for	88
of these cells	88
thought to be	88
type i ifn	88
inflammatory cytokines il	88
the percentage of	87
the interaction between	87
in patients of	87
the case of	87
patients with and	87
expression levels of	87
significantly higher than	87
for at least	87
were subjected to	87
in the generation	86
were analyzed by	86
patients with covid	86
we demonstrate that	86
was performed to	86
mrna expression in	86
results show that	86
in critically ill	86
measured by elisa	86
in a significant	86
to be associated	86
the possibility of	86
to healthy controls	86
cytokines in the	86
than that in	85
no significant differences	85
reduced in the	85
were used as	85
after stimulation with	85
large number of	85
objective of this	85
immune response and	85
of these cytokines	85
in a mouse	85
expression of genes	85
the proportion of	85
components of the	85
to measure the	85
was significantly increased	85
stability of the	85
a range of	85
were measured in	85
effects of the	85
consists of a	84
after the operation	84
end of the	84
seem to be	84
member of the	84
samples were obtained	84
a and b	84
expression of tlr	84
the pathophysiology of	84
with a high	84
in patients receiving	84
resulting in a	84
in patients who	84
inhibition of the	83
are able to	83
this work was	83
gd t cells	83
and the ability	83
in horses with	83
has been described	83
the choice of	83
in the cd	83
more frequent in	83
the surface of	82
it is not	82
did not correlate	82
induced release of	82
the complexity of	82
between the two	82
with the disease	82
the loss of	82
by b cells	82
the association of	82
expression in the	82
purpose of this	81
characterization of the	81
but not from	81
a crucial role	81
than in patients	81
c bl mice	81
of the molecule	81
have previously shown	81
production of the	81
have been identified	81
production of inflammatory	81
high amounts of	81
with septic shock	81
in t cells	81
after in vitro	81
are characterized by	80
not correlate with	80
in the cns	80
cytokine production in	80
concentration of the	80
of the complement	80
increased the expression	80
spinal cord injury	80
in the case	80
in cancer patients	80
of ms patients	80
the interaction with	80
a large number	80
the proliferation of	80
to be an	80
to be more	80
increased production of	79
the ratio of	79
major source of	79
did not change	79
the relation between	79
amounts of il	79
has been found	79
apoptotic cell death	79
a has been	79
a cell line	79
specific t cells	79
is based on	79
was performed with	79
of adhesion molecules	79
had no effect	79
needs to be	79
this cytokine is	79
the inflammatory cytokines	79
we used a	79
a patient with	79
the large intestine	79
the gastrointestinal tract	78
mrna expression was	78
nk cells in	78
have a higher	78
vitro stimulation of	78
t cell responses	78
status of the	78
and in vitro	78
in type diabetes	78
of inflammatory cells	78
the process of	78
the duration of	78
oxidative stress and	78
associated with poor	78
in the blood	78
allergic airway inflammation	78
activation of nf	78
is essential for	78
of our study	77
the interaction of	77
b cells and	77
intron of the	77
in this respect	77
respiratory syndrome coronavirus	77
mrna and protein	77
of the large	77
to differences in	77
no production in	77
results will be	77
t cells of	77
goal of the	77
high and low	77
cells were cultured	77
to contribute to	77
cytokines and chemokines	77
in the release	77
effect of these	77
significant difference in	77
up to weeks	77
to the c	77
which was not	76
the relation of	76
be used as	76
were exposed to	76
carcinoma cell line	76
in vitro studies	76
might be used	76
and septic shock	76
subsequent development of	76
examine the effects	76
apoptotic cells in	76
of endothelial cells	76
in healthy individuals	76
were divided into	76
some of the	76
blood cells and	76
human monoclonal antibody	75
a negative feedback	75
of the virus	75
contributes to the	75
regional lymph nodes	75
patients in the	75
resulted in an	75
shown to induce	75
and patients with	75
and production of	75
revealed that the	75
as detected by	75
inflammatory response to	75
was no significant	74
observed in patients	74
we were able	74
were randomized to	74
for cancer treatment	74
currently investigating the	74
be able to	74
with a history	74
previously shown that	74
terminal part of	74
single amino acid	74
ability to respond	74
to define the	74
a significant decrease	74
due to a	74
to the development	74
served as control	74
show that the	74
capacity to induce	74
are present in	74
is related to	74
could not be	74
presence or absence	74
has been suggested	74
a group of	74
upregulation of cd	74
these findings indicate	74
low levels of	73
due to differences	73
secretion of ifn	73
contrast to the	73
in the oral	73
is important to	73
used in this	73
a marker of	73
were collected and	73
or absence of	73
morbidity and mortality	73
we hypothesize that	73
are found in	73
was not significantly	73
in the joints	73
in modulation of	73
to investigate whether	73
in animal models	73
tnf and il	73
were found among	73
allele at position	73
type i ifns	73
risk of developing	73
in all patients	73
and mode of	73
we tested the	72
induction of cell	72
in the normal	72
a th phenotype	72
included in this	72
the appearance of	72
activity in the	72
is a potent	72
the extent of	72
prior to the	72
not altered by	72
high concentrations of	72
with an increase	72
the recruitment of	72
we have also	72
the range of	72
be attributed to	72
in the gc	72
large amounts of	72
elevated levels of	72
higher than that	72
the ear skin	72
of the host	72
results in a	72
blood donors were	72
in of the	71
result of the	71
to the control	71
the a a	71
and growth of	71
amino acid substitution	71
similarity to the	71
lead to a	71
possible role of	71
a fast and	71
a large panel	71
the regional lymph	71
towards a th	71
the in vitro	71
region of the	71
from healthy blood	71
and alveolar macrophages	71
large panel of	71
phase of the	71
associated with these	71
male and female	71
the small intestine	71
in both the	71
differences were found	71
immune response to	71
and tumor necrosis	71
aim was to	71
when compared with	71
in cultures of	71
immunity in the	71
were associated with	71
protease activity of	70
class i molecules	70
in a patient	70
was induced by	70
cells and platelets	70
the result of	70
which can be	70
which could be	70
the outcome of	70
monocytes and monocyte	70
induced by type	70
bronchial asthma with	70
are currently trying	70
in the last	70
were used for	70
and their related	70
currently trying to	70
of a number	70
their role in	70
mechanism of action	70
levels were significantly	70
and the subsequent	70
concentrations in the	70
of septic shock	70
in the management	70
of the examined	70
we have found	70
response to gram	70
g production in	70
with a th	70
a model of	70
levels of ifn	70
patients presented with	70
e and c	70
the patients with	70
and have no	69
considered to be	69
demonstrated by flow	69
as in healthy	69
of innate immunity	69
sera from healthy	69
levels and activity	69
specific cytotoxic t	69
mode of administration	69
than that of	69
with allergic rhinitis	69
virus nonstructural protein	69
the lcm virus	69
we have characterized	69
cells at all	69
levels of igg	69
antibody against the	69
the combination of	69
compared to ms	69
flow cytometry and	69
strains of lactobacillus	69
formation of mbp	69
activation through the	69
an insight of	69
trying to identify	69
is increasingly used	69
mechanism by which	69
evaluation of the	69
type ifn and	69
for survival and	69
presence of complement	69
to compare the	69
t dm patients	69
immune responses in	69
activate nk cells	69
subset of cd	69
oral mucosa and	69
may be related	69
are pattern recognition	69
increasingly used as	69
possibility to perform	69
respiratory syncytial virus	69
cytokine production and	69
the cysteine protease	69
day of age	69
binding to hla	69
and may be	69
patients of bronchial	69
negative feedback regulation	69
asthma with allergic	69
and activity were	69
provide an insight	69
and may thus	69
hc from stockholm	68
due to its	68
to reduce the	68
led to a	68
are potentially immunogenic	68
attempt to find	68
the noise threshold	68
cell response was	68
evaluated the adjuvant	68
a predisposing factor	68
serum mbl levels	68
s for h	68
of hyperbaric exposure	68
downregulated in crc	68
majority of responses	68
in protected rats	68
associated serine proteases	68
could provide an	68
bind to ospe	68
the examined s	68
of clonally expanded	68
an inflammatory response	68
in mbl ko	68
be responsible for	68
high mbl genotypes	68
as antiviral and	68
for more than	68
in mice immunized	68
iga and iga	68
and hc from	68
of tlr on	68
higher in patients	68
an assay for	68
coli and v	68
in ms from	68
ectopic gc have	68
were directed to	68
at the conference	68
of mt cells	68
by treatment with	68
of control donors	68
frequency of mt	68
the virus nonstructural	68
outside the pressurized	68
first to final	68
lactobacillus and bifidobacterium	68
their related molecules	68
to determine if	68
an increase of	68
mbl double ko	68
and allergic airway	68
of t cell	68
responsiveness ex vivo	68
role in modulation	68
upon recall stimulation	68
in wells with	68
the mt phenotype	68
the concentration in	68
in the frequencies	68
the mbl gene	68
during the dive	68
mucosa and may	68
target bacteria was	68
regions of ospe	68
tlr adaptor molecules	68
dm patients with	68
of gene expression	68
addition of dendritic	68
associated with higher	68
play a major	68
presence of dendritic	68
from sassari had	68
and bifidobacterium spp	68
with autologous bacteria	68
not from sassari	68
the vitamin e	68
mbl genotypes were	68
is difficult and	68
in the normoalbuminuric	68
nephropathy than in	68
presence of clonally	68
involved in ms	68
the normoalbuminuric group	68
the malarial antigen	68
a wide range	68
with nephropathy than	68
macrophages of ms	68
effects of hyperbaric	68
some time to	68
group of control	68
some capsulated s	68
phagocytosis of iga	68
selected on the	68
binding assays for	68
wide range of	68
donor t cells	68
be used in	68
in normal mucosa	68
double ko animals	68
complications in type	68
to activate nk	68
patients with nephropathy	68
to the activation	68
ratio of mt	68
from first to	68
project could provide	68
this project could	68
or the ear	68
in the mbl	68
the human collectins	68
to monitor patients	68
the pressurized chamber	68
lactobacillus rhamnosus gg	68
the gut flora	68
of c a	68
in normal colon	68
major histocompatibility complex	68
tlr on dcs	68
hyperbaric exposure on	68
levels and mbl	68
to final visit	68
for some time	68
of inflammatory mediators	68
of the mbl	68
pathogenesis of ae	68
including ingested probiotics	68
require laborious titrations	67
and antiviral neutralization	67
for antiviral activity	67
bioavailability varies with	67
patients and healthy	67
been demonstrated to	67
time to monitor	67
m protein and	67
a control group	67
immune response towards	67
pattern recognition receptors	67
of a a	67
all ifn species	67
assays require laborious	67
in a murine	67
the presence or	67
is regulated by	67
of the central	67
malaria in children	67
did not differ	67
acid substitution in	67
predisposing factor for	67
unique possibility to	67
nk cells may	67
children living on	67
used for some	67
assays for antiviral	67
living on the	67
programmed cell death	67
is crucial for	67
as a marker	67
a and mbl	67
and immunomodulatory therapies	67
used as antiviral	67
on the mddcs	67
in the antitumour	67
the application of	67
nk cells were	67
binding of mbl	67
species are potentially	67
in comparison with	67
mhc i molecules	67
species and mode	67
on ifn biologicals	67
on the coast	67
in mice with	67
laborious titrations making	67
ab and ab	67
novel markers for	67
and better reporter	67
role of mbl	67
used for the	67
mrna in cd	67
have been associated	67
no correlation between	67
making them unsuitable	67
acute myocardial infarction	67
new and better	67
one or more	67
monitor patients on	67
serum resistance of	67
of these genes	67
experimental autoimmune encephalomyelitis	67
a member of	67
ifn species and	67
able to induce	67
titrations making them	67
in the spleen	67
these assays require	67
levels were determined	67
hydrophobic interaction chromatography	67
coast of kenya	67
the coast of	67
inducible nitric oxide	67
cells as well	67
ifn species are	67
with ifn species	67
binding regions of	67
them unsuitable for	67
nk cells with	67
were performed using	67
and all ifn	67
varies with ifn	67
unsuitable for large	67
patients on ifn	67
predictive of pneumonia	66
of sarcoid origin	66
a mrna is	66
after h of	66
the occurrence of	66
g production and	66
invertebrate pattern recognition	66
of fizz and	66
and transduced cell	66
on the presence	66
the database system	66
been reported in	66
interaction chromatography and	66
and after the	66
to obtain tumour	66
aim of our	66
inflammatory cytokines and	66
and svegfr concentrations	66
scale clinical use	66
in sentinel nodes	66
plasma svegf and	66
activation of oas	66
variant tumour cells	66
this is the	66
cell reactivity in	66
of reactive oxygen	66
our observation that	66
and identifies a	66
pattern recognition molecule	66
standard operating procedures	66
a was lower	66
before clinical signs	66
was higher in	66
concentrations of il	66
membrane depolarization in	66
in sentinel lymph	66
survival and growth	66
of c def	66
risk factor for	66
on intercellular contact	66
versus mg l	66
oligoadenylate synthetases are	66
transduced cell lines	66
a hierarchy of	66
for malaria in	66
induced complement activity	66
cells of c	66
response towards a	66
streptococcal m protein	66
mbl and ficolins	66
observation that c	66
soluble vascular endothelial	66
control and transduced	66
the two groups	66
and svegfr from	66
our aim was	66
in one study	66
have no enhanced	66
chain of masp	66
to the same	66
type ii cytokine	66
highthroughput global proteome	66
fizz and ym	66
can be detected	66
a risk factor	66
identification of such	66
induced rantes expression	66
ag a dna	66
species of lab	66
depended on intercellular	66
the mbl pathway	66
which is a	66
simplex virus type	66
have investigated the	66
mbl masp activity	66
a responsiveness ex	66
cutaneous lymphocyteassociated antigen	66
of ae to	66
significant differences in	66
in the lectin	66
a unique possibility	66
nonsentinel lymph nodes	66
blood donors was	66
splenic cd b	66
development of immunological	66
against pulmonary tb	66
hospital of thessaloniki	66
during surgery and	66
domain of ccf	66
novel allergen carriers	66
cultures of sarcoid	66
ae to modulate	66
for use in	66
development of loss	66
mice compared to	66
in this group	66
levels were higher	66
marginal zone macrophages	66
and mbl masp	66
inflammatory response syndrome	66
of the mouse	66
the current study	65
the progression of	65
decrease in the	65
for induction of	65
the detection of	65
little is known	65
to inhibit the	65
compared to normal	65
on the surface	65
role of this	65
linked to the	65
we did not	65
and function of	65
contributing to the	65
involved in this	65
the cell cycle	65
lower levels of	65
were tested for	65
in vitro with	65
to respond to	65
have been observed	65
of these patients	65
between the groups	65
as a control	65
analyses were performed	65
an inhibitor of	64
nk cells and	64
of b cells	64
the protective effect	64
investigation of the	64
mg kg day	64
these findings suggest	64
these cells were	64
as a major	64
results of this	64
may provide a	64
the in vivo	64
the cause of	64
school of medicine	64
were identified by	64
did not show	64
in the skin	64
type i interferon	64
of the cells	64
pcr was performed	64
a and c	64
inflammatory response in	64
are elevated in	64
breast cancer cell	64
regions of the	64
leads to a	63
of this cytokine	63
correlated with the	63
caused by the	63
in the circulation	63
were significantly lower	63
in the range	63
have found that	63
and for the	63
similar in both	63
in the serum	63
it should be	63
the study of	63
exposed to the	63
our findings suggest	63
mechanism for the	63
polymerase chain reaction	63
in human and	63
have also been	62
many of these	62
activation in the	62
an in vitro	62
patients with multiple	62
in relation to	62
was to examine	62
was performed by	62
crucial role in	62
can be found	62
presence of an	62
of mice with	62
to be significantly	62
involvement of the	62
were isolated and	62
juvenile idiopathic arthritis	62
and the development	62
is known about	62
in this regard	62
in in vitro	62
has been implicated	62
were increased in	62
mhc class i	61
be activated by	61
in rheumatoid arthritis	61
stimulation of the	61
as a potential	61
mesenchymal stem cells	61
rheumatoid arthritis and	61
is a key	61
can lead to	61
results of the	61
and duration of	61
to analyze the	61
may not be	61
and has been	61
dendritic cells and	61
we investigated whether	61
duration of the	61
significantly lower in	61
with regard to	61
the determination of	60
of the other	60
a dose of	60
of cytokines in	60
may result in	60
of the three	60
many of the	60
was no correlation	60
compared to those	60
it is important	60
the stability of	60
was lower in	60
of apoptotic cells	60
is capable of	60
expression in human	60
in endothelial cells	60
parts of the	60
is increased in	60
as compared with	60
patients treated with	60
expressed in the	60
we have used	60
mouse and human	60
was not associated	60
correlation between the	60
which is associated	60
is independent of	59
was observed for	59
and the activation	59
in the lungs	59
suggests that the	59
of the normal	59
increased susceptibility to	59
independent of the	59
of the receptor	59
randomized to receive	59
influenced by the	59
may help to	59
tnf production in	59
at the site	59
the mechanisms underlying	59
the changes in	59
two types of	59
remains to be	59
the migration of	59
followed by a	59
different time points	59
did not affect	59
significant decrease in	59
is a common	59
we also found	59
days after the	59
of the genes	59
high degree of	59
of these molecules	59
may have a	58
cells into the	58
in septic patients	58
of the target	58
years of age	58
is considered as	58
and it is	58
the presence and	58
age of the	58
the integrity of	58
as shown in	58
the t cell	58
risk factors for	58
we observed a	58
immune response in	58
functions of the	58
on the expression	58
in more detail	58
has been proposed	58
significant difference between	58
maternal and fetal	58
in the course	58
acts as a	58
a cohort of	58
reduction in the	58
have been demonstrated	58
the mechanisms of	58
depends on the	58
by the same	58
cell death in	58
work was supported	57
has previously been	57
are thought to	57
we analyzed the	57
at different time	57
c a and	57
is to evaluate	57
was performed on	57
plays a role	57
using flow cytometry	57
a significant reduction	57
plays a pivotal	57
were present in	57
were added to	57
production of ifn	57
was obtained from	57
belongs to the	57
was able to	57
to find out	57
of cytokines and	57
was independent of	57
differences between the	57
due to their	57
the bone marrow	57
characterized by a	57
have been suggested	57
by the fact	57
and results in	57
molecules in the	57
variation in the	57
class ii mhc	57
after exposure to	57
in the number	57
lead to the	57
not observed in	57
on the cell	56
tested the hypothesis	56
difference in the	56
that expression of	56
and c a	56
function of the	56
the basis for	56
on t cells	56
we sought to	56
it is known	56
significant reduction in	56
at least one	56
was significantly associated	56
previously demonstrated that	56
expression pattern of	56
binding to the	56
to analyse the	56
evidence indicates that	56
are activated by	56
closely related to	56
in the inflammatory	56
specific cd t	56
and control groups	56
control of the	56
was no difference	56
the reduction of	56
recent studies have	56
in septic shock	56
heat shock protein	56
was obtained by	56
and tumour necrosis	56
level in the	56
not fully understood	56
as the most	56
to that of	56
was increased in	56
material and methods	56
nitric oxide production	56
lower than that	55
of the expression	55
the first step	55
after incubation with	55
a consequence of	55
in the immune	55
and maintenance of	55
in cases of	55
for detection of	55
in the plasma	55
crucial for the	55
vascular smooth muscle	55
was defined as	55
statistical analysis was	55
and treatment of	55
was confirmed by	55
the help of	55
in the tnf	55
is a potential	55
a monoclonal antibody	55
of neutrophils and	55
mechanisms underlying the	55
the concept of	55
may be useful	55
inflammatory gene expression	55
which is not	55
of class ii	55
to the severity	55
correlated with a	55
upregulation of the	55
in human monocytes	55
treatment of inflammatory	55
at the onset	55
immune responses to	55
we analysed the	55
were performed with	55
of regulatory t	55
over a period	55
the magnitude of	55
cell growth and	55
studies are required	55
during the acute	54
as a model	54
the sequence of	54
to elucidate the	54
and the risk	54
human and mouse	54
previously reported that	54
is a very	54
is not known	54
and release of	54
for the production	54
in the high	54
the cellular and	54
cells has been	54
resulting in an	54
prove to be	54
human immunodeficiency virus	54
and the presence	54
disease of the	54
myelin basic protein	54
in recent years	54
in the majority	54
have revealed that	54
of the small	54
mast cell degranulation	54
a target for	54
directly or indirectly	54
play a central	54
mrna levels of	54
mrna expression of	54
that can be	54
a and ifn	54
at least in	54
in ra patients	54
the cytokine storm	54
a possible role	53
is that the	53
inactivation of the	53
the differences in	53
of ng ml	53
a high degree	53
department of molecular	53
the need for	53
in mammalian cells	53
and a significant	53
the phenotype of	53
it is possible	53
vivo and in	53
and or the	53
aimed to investigate	53
patients who received	53
in host defense	53
and transforming growth	53
that of the	53
secretion of il	53
of type i	53
derived dendritic cells	53
more pronounced in	53
to have a	53
to the human	53
study was undertaken	53
has a high	53
shown to increase	53
the difference in	53
the maturation of	53
cells with a	53
was noted in	53
in this model	53
inflammatory cytokines such	53
is effective in	53
can act as	53
restricted to the	53
known to play	53
not seem to	52
of inflammatory diseases	52
with those of	52
in the central	52
of the p	52
presence of the	52
macrophage activation syndrome	52
the type of	52
transcription of the	52
gene expression profiles	52
by dendritic cells	52
maintenance of the	52
experiments showed that	52
in agreement with	52
fact that the	52
in the response	52
data not shown	52
the differentiation of	52
the existence of	52
and stimulated with	52
were correlated with	52
the nature of	52
levels are elevated	52
with the help	52
g and il	52
studied the effect	52
patients and normal	52
both types of	52
order to study	52
intercellular adhesion molecule	52
has been associated	52
corresponding to the	52
step in the	52
for patients with	52
its role in	52
is present in	52
of immune cells	52
factors such as	52
compared to patients	52
we aim to	52
have previously demonstrated	52
compared to other	52
knowledge of the	52
in a variety	52
fold increase in	51
are regulated by	51
into the nucleus	51
was significantly lower	51
between patients with	51
mice with the	51
were used in	51
in the host	51
necrosis factor receptor	51
participate in the	51
to the clinical	51
was performed in	51
nature of the	51
the maintenance of	51
recently demonstrated that	51
performed using a	51
in the gut	51
higher concentration of	51
has been observed	51
of the control	51
the data were	51
ability to produce	51
activity may be	51
not significantly different	51
carried out to	51
the clearance of	51
cell line was	51
in the production	51
the acute phase	51
the peripheral blood	51
addition to the	51
primary and secondary	51
with a lower	51
the inflammatory process	51
values of the	51
in the innate	51
c mice were	51
the distribution of	51
structure of the	51
admitted to the	51
from ms patients	51
determined by the	51
in colorectal cancer	51
was undertaken to	51
cytokine production by	51
also known as	51
in the pathophysiology	51
expression of a	51
that may be	51
the viability of	51
of chronic inflammatory	51
cell adhesion molecules	51
is caused by	51
located at the	51
monoclonal antibodies to	50
are expressed in	50
study was carried	50
it can be	50
derived from the	50
our data suggest	50
were significantly increased	50
which leads to	50
molecules involved in	50
polymorphism in the	50
a murine model	50
mainly in the	50
was a significant	50
the increase of	50
of the tnf	50
samples were drawn	50
are responsible for	50
determined in the	50
a subset of	50
may be the	50
as a consequence	50
department of surgery	50
higher risk of	50
inflammatory cytokines in	50
was examined by	50
important role for	50
in diabetic patients	50
to promote the	50
vascular endothelial cells	50
has been established	50
the uptake of	50
in ms patients	50
all of the	50
p and p	50
of mg kg	50
may be an	50
the requirement for	50
in plasma and	50
that these cells	50
was measured in	50
observed in a	50
of the proteins	50
method for the	50
course of the	50
mice infected with	50
and severity of	50
with increased levels	50
expression of several	50
it is also	50
bei patienten mit	50
signal transduction pathways	50
critical for the	50
intensity of the	50
growth and development	50
group than in	49
proinflammatory cytokines such	49
which are the	49
been observed in	49
especially in the	49
seen in the	49
in cd t	49
was compared to	49
confined to the	49
at the level	49
and intensive care	49
leads to increased	49
propose that the	49
results in increased	49
domain of the	49
an association of	49
this group of	49
could be an	49
data of the	49
was seen in	49
effect was observed	49
been used as	49
the study and	49
essential for the	49
may influence the	49
be observed in	49
human endothelial cells	49
the light of	49
tended to be	49
for this purpose	49
the possibility to	49
cells and is	49
to those of	49
the p mapk	49
measured by a	49
on the same	49
these cytokines are	49
in a single	49
t cells into	49
the last decade	49
content of the	49
previously been shown	49
similar to those	49
we previously reported	49
in the light	49
in the adult	49
in macrophages of	49
endothelial cells and	49
consistent with the	48
samples were taken	48
human and murine	48
act as an	48
such as ifn	48
sera from patients	48
first line of	48
were observed for	48
was analyzed by	48
was added to	48
treatment in the	48
of no production	48
levels may be	48
within the first	48
study was designed	48
hepatitis c virus	48
the contribution of	48
and survival of	48
the impairment of	48
a and a	48
that the use	48
content in the	48
patients suffering from	48
and to investigate	48
of epithelial cells	48
were no significant	48
murine and human	48
is critical for	48
which has been	48
to predict the	48
are crucial for	48
in our laboratory	48
insights into the	48
infection is the	48
component of the	48
the proinflammatory cytokine	48
studies have demonstrated	48
time pcr was	48
of innate and	48
is known that	48
animal models of	48
the growth of	48
applied to the	48
of the population	48
in patients and	48
our study was	48
antibodies in the	48
to the virus	48
activation of inflammatory	48
demonstrated that the	48
to be activated	48
have examined the	48
first step in	48
response was observed	48
data show that	48
could lead to	48
and on the	48
not to be	48
molecular and cellular	48
association of the	48
can be applied	48
the modulation of	48
increase of il	48
of cell cycle	48
cell surface markers	47
at day of	47
point of view	47
led to the	47
does not seem	47
infection with the	47
the vast majority	47
cells may be	47
in the gastric	47
cell lines in	47
indicates that the	47
light of the	47
play a critical	47
dose of mg	47
molecules of the	47
cell proliferation was	47
be noted that	47
we evaluated the	47
to be able	47
was not influenced	47
should be considered	47
be applied to	47
on peripheral blood	47
will be discussed	47
with multiple sclerosis	47
none of the	47
the intensive care	47
these cells in	47
with a significant	47
considered statistically significant	47
induction of the	47
increases in the	47
the possibility that	47
inflammatory effects in	47
been reported that	47
be considered as	47
released by activated	47
target for the	47
result of a	47
in the design	47
examined the expression	47
in the upper	47
at a dose	47
inhibitory effect of	47
in this process	47
obtained from the	47
immune status of	47
development of a	47
p and tnf	47
of the known	47
induced by the	47
a systematic review	47
based on a	47
it was shown	47
incubated with the	47
infections in the	47
in case of	47
is sufficient to	47
it would be	47
has been postulated	47
phases of the	47
activated by the	47
to the controls	47
cell cycle and	47
used to determine	47
of the first	47
b cells from	47
suggesting that the	47
apache ii score	47
in parallel with	47
were stained with	47
sepsis and septic	47
in accordance with	47
were evaluated by	47
could play a	47
as tnf and	47
were cultured with	47
or in combination	47
pregnant women with	46
required for the	46
stimulated in vitro	46
to improve the	46
is the major	46
peripheral blood samples	46
was significantly reduced	46
was inhibited by	46
a regulatory role	46
point to a	46
inflammation in the	46
in the formation	46
cell response to	46
gene expression and	46
to the cells	46
treatment did not	46
no statistically significant	46
and mg kg	46
which is the	46
is induced in	46
were generated by	46
vast majority of	46
studies revealed that	46
was considered statistically	46
important for the	46
from healthy volunteers	46
at this time	46
in group a	46
did not inhibit	46
were collected from	46
belonging to the	46
patients with sle	46
should be noted	46
immune responses against	46
type diabetes and	46
present study we	46
alone or in	46
in a clinical	46
the capability of	46
in production of	46
have been implicated	46
adhesion molecules in	46
and environmental factors	46
by activated macrophages	46
and the cytokine	46
of th and	46
in the peripheral	46
in the supernatants	46
the most potent	46
important implications for	46
the cytokine production	46
t cell response	46
the frequency and	46
and increased the	46
healthy control subjects	46
cytokine response to	46
of cell proliferation	46
susceptibility to infections	46
been found in	46
a useful tool	46
the immune status	46
t cells during	46
a predictor of	46
is the predominant	46
may account for	46
may be due	46
our understanding of	46
the pattern of	46
during infection with	46
increased significantly in	46
studies showed that	46
more likely to	46
in the low	46
we have examined	46
in normal human	46
of the tlr	46
receptor expression in	46
and regulation of	46
response to infection	46
was designed to	46
has demonstrated that	46
to find a	46
referred to as	46
in these studies	46
as a therapeutic	46
higher than in	45
production in response	45
located in the	45
of response to	45
formation of the	45
portion of the	45
stage renal disease	45
when it is	45
the cytokine response	45
molecular mechanisms of	45
not influenced by	45
acute renal failure	45
to produce the	45
characterized by increased	45
macrophages and lymphocytes	45
the observation period	45
a reduction of	45
be useful in	45
the first hours	45
to the disease	45
epithelial cell line	45
efficacy and safety	45
expression was evaluated	45
oxidative stress in	45
antibodies specific for	45
from whole blood	45
and safety of	45
of the anti	45
produced by the	45
were shown to	45
by use of	45
our results show	45
the surface expression	45
to the first	45
in these cells	45
data demonstrate that	45
that they are	45
differential expression of	45
and development of	45
compared to wildtype	45
protein that is	45
and b cells	45
that both the	45
of the intestinal	45
after the last	45
indicating that this	45
the alternative pathway	45
to a lesser	45
to monitor the	45
total rna was	45
was isolated and	45
of this molecule	45
with a molecular	45
also capable of	45
cell cultures were	45
is believed to	45
murine model of	45
an involvement of	45
we have tested	45
further studies are	45
specific for the	45
response in the	45
both innate and	45
overexpression of the	45
a higher risk	45
of the model	45
a th response	45
processes in the	45
concentrations were significantly	45
of the binding	45
it is difficult	45
in a horse	45
genes were significantly	45
by type i	45
patients with septic	45
is not fully	45
a dose dependent	45
cell activation in	45
is still unclear	45
cause of death	45
led to increased	45
used to identify	45
these data indicate	45
in the current	45
a family of	45
and mortality in	45
and healthy individuals	45
recently reported that	45
by virtue of	45
positive cells in	44
been used to	44
were analysed using	44
production of pro	44
believed to play	44
expansion of cd	44
the initial phase	44
of inflammation and	44
the immune responses	44
that the majority	44
there is increasing	44
cells that are	44
is accompanied by	44
is increasing evidence	44
for management of	44
is an autoimmune	44
colon cancer cell	44
after treatment with	44
fusion of the	44
inflammation of the	44
in a model	44
by the induction	44
this may be	44
at increased risk	44
of disease and	44
no association between	44
similar to that	44
of allergic asthma	44
disseminated intravascular coagulation	44
a form of	44
lower risk of	44
a naturally occurring	44
patients infected with	44
and stimulation of	44
was present in	44
and the concentration	44
of the hla	44
used to investigate	44
an upregulation of	44
receptors of the	44
and characterization of	44
the cytokine profile	44
there is an	44
control group was	44
of the total	44
in a cohort	44
by these cells	44
in the n	44
also been found	44
family history of	44
genes can be	44
an increased risk	44
fold higher in	44
is not due	44
on the host	44
to the group	44
the selection of	44
to the pathogenesis	44
in the following	44
characterized by the	44
be explained by	44
are needed to	44
of a patient	44
in the whole	44
on cell proliferation	44
studies indicated that	44
h after the	44
of the lung	44
effects of this	44
is recognized by	44
with rheumatoid arthritis	44
might be a	44
may be attributed	44
implications for the	44
to play an	44
the presentation of	43
known for their	43
been identified as	43
in sera of	43
plasma samples were	43
plasma concentrations of	43
during the period	43
we explored the	43
suggest a possible	43
cells in peripheral	43
antibodies against the	43
blood sample was	43
healthy individuals and	43
lung injury in	43
mutations in the	43
the accumulation of	43
inflammatory response and	43
layer of the	43
on a single	43
were performed in	43
circulating levels of	43
specific immune response	43
studies suggest that	43
in an increased	43
to be directly	43
were assayed for	43
p map kinase	43
statistically significant differences	43
to optimize the	43
proteins such as	43
are not yet	43
it is a	43
ability to activate	43
in group b	43
should be further	43
our data provide	43
increased release of	43
production induced by	43
preliminary results suggest	43
production in macrophages	43
from healthy controls	43
the prevention of	43
surface plasmon resonance	43
a major source	43
increase of the	43
were cultured in	43
in each group	43
of adaptive immunity	43
and exposed to	43
were capable of	43
we identified a	43
these results may	43
in infected cells	43
stimulated with il	43
in serum of	43
and in addition	43
of the novel	43
were measured using	43
we found a	43
for the expression	43
percentage of cells	43
as part of	43
analysis showed that	43
chronic inflammatory disease	43
treatment of covid	43
proliferation of the	43
no differences in	43
in type diabetic	43
of cardiovascular disease	43
of this gene	43
t cells showed	43
mice were immunized	43
examined the effects	43
will also be	43
used to assess	43
induced by an	43
result in a	43
other autoimmune diseases	43
activated t cells	43
complexity of the	43
of cd by	43
in the icu	43
and characterized by	43
the phosphorylation of	43
were measured on	43
to increase in	43
significant increase of	43
beneficial effects on	43
direct effect of	43
further characterization of	43
would be a	43
but not cd	43
coding for the	43
compared to baseline	43
expression in both	43
were immunized with	43
with poor prognosis	42
initial phase of	42