bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
extracellular vesicles	578
summary conclusion	561
study design	534
blood donors	497
case studies	483
background case	481
summary conclusions	468
whole blood	435
design method	387
results finding	375
red blood	371
nucleic acid	319
blood group	316
blood bank	304
flow cytometry	273
blood transfusion	270
electron microscopy	243
blood cells	243
blood donation	241
red cell	226
blood products	211
blood components	206
bone marrow	203
blood cell	196
positive samples	189
mg kg	181
performed using	179
clinical samples	171
stem cell	171
mg dl	168
blood donor	158
cell lines	158
significantly higher	157
public health	157
chain reaction	152
sample preparation	150
respiratory tract	147
derived evs	147
blood samples	146
results findings	144
polymerase chain	144
blood center	142
western blot	142
nanoparticle tracking	142
mass spectrometry	141
transfusion reactions	139
design methods	138
tracking analysis	138
nucleic acids	136
clinical signs	133
infectious diseases	131
transfusion medicine	130
ng ml	129
see chapter	128
gene expression	125
statistically significant	121
time pcr	120
significant differences	116
significant difference	114
lateral flow	114
red cells	114
influenza virus	112
blood product	112
stem cells	112
mg ml	111
transmission electron	108
isothermal amplification	107
quality control	105
room temperature	103
transfusion service	103
viral load	102
cancer cells	101
blood donations	101
samples collected	101
platelet count	101
united states	100
rbc units	100
control group	99
risk factors	99
determine whether	97
present study	96
total number	96
platelet concentrates	94
peripheral blood	93
blood supply	93
first time	92
adverse events	92
sample collection	92
breast cancer	91
acute respiratory	90
nanopore sequencing	88
histologic study	88
generation sequencing	85
plasma samples	85
doc id	85
cord uid	85
author funder	83
spinal cord	83
fecal samples	83
granted medrxiv	83
extracellular vesicle	81
least one	81
usa introduction	81
blood services	81
clinically significant	80
prostate cancer	80
associated conditions	79
possible associated	78
commercially available	78
exclusion chromatography	78
scanning electron	77
pregnant women	76
see also	76
cell culture	75
medical center	75
cell types	75
specimen preparation	75
cell line	74
derived exosomes	74
may also	73
serum samples	73
genomic dna	73
iu ml	72
significantly lower	72
blood banks	70
significantly different	70
reverse transcription	70
blood centers	70
respiratory syndrome	70
derived extracellular	69
upper respiratory	69
copyright holder	69
body weight	68
escherichia coli	68
expected findings	68
recipient cells	68
sickle cell	68
two different	67
air samples	67
tissue samples	67
two groups	66
viral rna	66
version posted	66
healthy dogs	66
deep sequencing	65
western blotting	65
red cross	65
cancer cell	65
related terms	64
antibody screen	64
amino acid	64
results suggest	63
commonly used	63
differentially expressed	63
size exclusion	63
blood collection	63
mesenchymal stem	62
positive results	62
sample size	62
monte carlo	62
two samples	62
antibody screening	62
world health	61
massive transfusion	61
endothelial cells	61
mean age	61
blood pressure	61
rhce ce	61
analyzed using	61
widely used	60
health organization	60
rbc transfusion	60
made available	60
library preparation	60
blood component	60
external examination	59
sanger sequencing	59
statistical analysis	59
illumina miseq	59
faecal samples	59
diagnostic tests	59
patient samples	59
mediated isothermal	59
antigen expression	59
epithelial cells	58
blood service	58
adverse reactions	58
health care	58
within hours	58
transfusion reaction	58
severe acute	57
ev isolation	57
iron deficiency	57
pcr amplification	57
submit samples	57
clinical practice	57
size distribution	57
false positive	56
national blood	56
transfusion services	56
flow strip	56
negative results	56
immune response	56
hematopoietic stem	56
test results	56
small rna	55
rna sequencing	55
cell disease	55
blood safety	55
age group	55
previous studies	55
study period	55
peer review	54
next generation	54
statistical significance	54
swab samples	54
one sample	54
samples tested	54
blood type	54
acid amplification	54
hemolytic transfusion	53
infectious disease	53
rhd gene	53
respiratory viruses	53
rna extraction	53
rna viruses	53
density gradient	53
abstract withdrawn	53
culture media	52
large number	52
per sample	52
exposed controls	52
blood volume	52
rapid detection	52
total rna	52
pathogen reduction	52
apheresis platelets	51
ferritin levels	51
electron beam	51
negative samples	51
respiratory disease	51
dna sequencing	51
electron microscope	51
ms ms	51
pg ml	51
dna extraction	51
international license	51
standard deviation	51
time donors	50
risk factor	50
viral loads	50
blood loss	50
cancer patients	50
previously described	50
significantly increased	50
clinically relevant	50
hand column	49
medical records	49
cd cells	49
genome sequencing	49
group system	49
viral contigs	49
samples using	49
measured using	49
human plasma	49
heart failure	48
patient blood	48
age groups	48
virus infection	48
blood sample	48
results indicate	48
immune system	48
control samples	48
significantly reduced	48
mental health	48
three different	48
trima accel	48
bacterial contamination	47
data analysis	47
acute samples	47
donor selection	47
surface markers	47
small extracellular	47
blood management	47
female donors	47
ct values	47
differential ultracentrifugation	47
novel coronavirus	47
respiratory samples	47
nervous system	47
negative control	47
important role	47
center background	46
informed consent	46
systematic review	46
sequencing data	46
abo rh	46
molecular diagnostics	46
cfu ml	46
water supply	45
liquid biopsy	45
retrospective study	45
tested using	45
pig farmers	45
analysis revealed	45
drug resistance	45
conditioned media	45
study aimed	45
plasma exchange	45
copies ml	44
high throughput	44
lymph nodes	44
urine samples	44
procedures depend	44
urinary bladder	44
submit sample	44
heart disease	44
viral pathogens	44
evs derived	44
ev markers	44
isolated evs	44
turnaround time	44
cerebrospinal fluid	44
results obtained	44
high risk	44
growth factor	44
multiplex pcr	43
patient care	43
median age	43
monoclonal antibody	43
type i	43
years old	43
based methods	43
clinical specimens	43
ev cargo	43
may occur	43
platelet counts	43
intercellular communication	43
significant increase	43
real time	43
viral reads	43
see table	42
medrxiv preprint	42
terumo bct	42
asian dust	42
isolation methods	42
sequence data	42
cell surface	42
main hydrated	42
immunodeficiency virus	42
hemolytic anemia	42
per year	42
time rt	41
isolated using	41
antiglobulin test	41
patients undergoing	41
metagenomic sequencing	41
data suggest	41
zika virus	41
ev release	41
grossly identified	41
repeat donors	41
lower respiratory	41
pool size	41
healthy controls	41
male donors	41
whole genome	41
intensive care	41
tumour cells	41
platelet function	41
frozen plasma	41
anomaly detection	41
may provide	40
medical record	40
may lead	40
positive sample	40
significantly decreased	40
acid testing	40
reference laboratory	40
results showed	40
university hospital	40
thermo fisher	40
tract infections	40
high sensitivity	40
assessed using	40
identified abnormalities	40
logistic regression	40
wide range	40
blood transfusions	39
biological samples	39
current study	39
bact alert	39
analysis showed	39
blood groups	39
waterborne illness	39
evs isolated	39
plasma units	39
flow cytometric	39
fisher scientific	39
heart rate	39
adverse effects	39
wound healing	39
different types	39
pcr assay	39
diabetes mellitus	39
liver disease	39
cord blood	39
lymph node	39
donor samples	38
reverse transcriptase	38
negative controls	38
treated cells	38
tested positive	38
conditioned medium	38
first step	38
transfusion practice	38
previously reported	38
platelet transfusion	38
hydrated hcqs	38
drinking water	38
antibody identification	38
liquid chromatography	38
year old	38
clinical trials	38
clinical trial	38
future studies	38
urinary tract	38
differential centrifugation	37
evaluated using	37
pilot study	37
may cause	37
determined using	37
respiratory syncytial	37
rhd genotyping	37
platelet aggregation	37
magnetic beads	37
protein content	37
evs released	37
blood units	37
machine learning	37
specific primers	37
even though	37
ex vivo	37
pcr assays	37
high prevalence	37
healthy donors	37
faecal virome	37
lung cancer	37
proteomic analysis	37
platelet units	36
test result	36
cross section	36
pcr products	36
body mass	36
stool samples	36
septal defect	36
case report	36
ml kg	36
results show	36
dna samples	36
patient safety	36
highly sensitive	36
human immunodeficiency	36
scd patients	36
single nucleotide	36
analysis using	36
diagnostic test	36
month period	35
fully automated	35
may result	35
diagnostic testing	35
increased risk	35
based detection	35
contrast material	35
urine sample	35
pig buildings	35
rhd negative	35
relative abundance	35
cell transplantation	35
therapeutic plasma	35
fresh frozen	35
analysed using	35
diagnostic tools	35
expression levels	35
water quality	35
renal failure	35
voluntary blood	34
using two	34
cell proliferation	34
group antigens	34
white blood	34
farmworker families	34
platelet products	34
transfusion safety	34
may help	34
molecular testing	34
also performed	34
pathogen inactivation	34
monoclonal antibodies	34
cd cd	34
safe blood	34
total protein	34
sample pooling	34
ev subpopulations	34
hemolytic disease	34
abo blood	34
bacterial culture	34
syncytial virus	34
side effects	34
growth factors	34
sample processing	34
protein expression	34
plasma evs	34
target enrichment	34
reference genome	33
oxidative stress	33
kidney disease	33
one year	33
recent years	33
additive solution	33
fold increase	33
pooled samples	33
hb levels	33
also found	33
iron supplementation	33
infection control	33
without fip	33
genome sequence	33
per ml	33
procedures described	33
linear regression	33
veterinary medicine	33
particle size	33
viral infections	33
emerging infectious	33
body condition	33
lg ml	32
high level	32
retrospective analysis	32
molecular diagnostic	32
time points	32
patients received	32
contigs singletons	32
complete genome	32
randomly selected	32
capillary electrophoresis	32
small evs	32
information system	32
one patient	32
etiologic agent	32
preliminary data	32
closely related	32
prospective study	32
new york	32
sequencing reads	32
hours post	32
storage period	32
data show	32
among blood	32
odds ratio	32
patients receiving	32
surface area	31
dna amplification	31
serum albumin	31
cell communication	31
clinical data	31
ct value	31
individual samples	31
consensus sequences	31
pediatric patients	31
blood vessels	31
target cells	31
gold standard	31
viral sequences	31
data collected	31
three samples	31
gastrointestinal tract	31
cell units	31
molecular detection	31
resistance genes	31
protein cargo	31
using flow	31
time point	31
time series	31
ill persons	30
bronchoalveolar lavage	30
buffy coat	30
low hb	30
cohort study	30
study population	30
regression analysis	30
positive donations	30
virus detection	30
illumina sequencing	30
nasopharyngeal swabs	30
viral detection	30
staphylococcus aureus	30
genome sequences	30
also tested	30
regional blood	30
transfusion protocol	30
clinical symptoms	30
calculated using	30
relatively high	30
social media	30
apheresis platelet	30
transfused patients	30
left ventricular	30
plasma membrane	30
infectious agents	30
viral families	30
umbilical cord	29
small number	29
central nervous	29
vitro quality	29
virus reads	29
transfusion vol	29
reads mapping	29
last years	29
donor screening	29
shelf life	29
dna barcoding	29
randomized controlled	29
ev production	29
within days	29
stromal cells	29
recent studies	29
toxicologic study	29
tumour microenvironment	29
viral genomes	29
fully integrated	29
mouse model	29
transport medium	29
ebola virus	29
american red	29
surface marker	29
positive control	29
also used	29
antimicrobial resistance	29
family members	29
tract infection	29
human genome	29
reference sequence	29
high frequency	29
tandem mass	29
early detection	28
donate blood	28
supplement iv	28
body fluids	28
nasopharyngeal swab	28
cd expression	28
inclusion criteria	28
physical examination	28
scanning vol	28
diagnostic sensitivity	28
per month	28
packed red	28
control dogs	28
high quality	28
transmitted infections	28
low viral	28
autologous blood	28
false negative	28
ethics committee	28
general population	28
viral infection	28
naturally occurring	28
type ii	28
optical reader	28
high titer	28
acid extraction	28
tube method	28
respiratory pathogens	28
false positives	28
three groups	28
donor population	28
new zealand	28
culture medium	28
samples taken	28
high levels	28
bacterial species	28
rbc transfusions	28
time period	28
year period	28
quality assurance	27
transfusion transmitted	27
electronic medical	27
mitral valve	27
smooth muscle	27
host cells	27
rare donor	27
weak positive	27
higher risk	27
population density	27
exosomes derived	27
high resolution	27
multiple myeloma	27
pcr reaction	27
clinical significance	27
circulating evs	27
prevalence rate	27
water treatment	27
solid phase	27
target dna	27
blood system	27
flow cytometer	27
air embolism	27
molecular weight	27
direct antiglobulin	27
mean ae	27
extracellular matrix	27
quantified using	27
indirect antiglobulin	27
nasal cavity	27
hbv dna	27
incubation period	26
throughput sequencing	26
units transfused	26
transfusion recipients	26
hospital transfusion	26
per day	26
immune cells	26
human serum	26
protein markers	26
one week	26
considered significant	26
cross sections	26
influenza viruses	26
monoclonal anti	26
disease surveillance	26
physical activity	26
samples showed	26
infected individuals	26
normal dogs	26
old female	26
cell transfusion	26
cell carcinoma	26
coronary artery	26
water samples	26
inventory management	26
confidence interval	26
phylogenetic analysis	26
rheumatoid arthritis	26
days post	26
negative blood	26
weight loss	26
human health	26
respiratory infections	26
nasopharynx samples	26
transfusion therapy	26
endothelial cell	26
findings suggest	26
spectra optia	26
fatty acid	26
master mix	26
developing countries	26
specific antibodies	26
dengue virus	26
blot analysis	26
clinical setting	26
also observed	26
sample types	26
affected dogs	26
transfusion practices	26
significantly associated	26
complete blood	25
bacterial growth	25
infected cells	25
blood alcohol	25
blood count	25
tertiary care	25
coronavirus disease	25
disease control	25
column agglutination	25
clinical outcomes	25
wild type	25
environmental dna	25
platelet transfusions	25
will help	25
confocal microscopy	25
cats without	25
hiv urine	25
compared using	25
iron depletion	25
results demonstrate	25
nasopharyngeal flora	25
free dna	25
based assays	25
bowel disease	25
viral genome	25
using different	25
hla antibodies	25
compatible blood	25
vast majority	25
described previously	25
obtained using	25
information regarding	25
platelet content	25
four samples	25
inflammatory response	25
detection methods	25
class i	25
syndrome coronavirus	25
much higher	25
bacillus anthracis	25
may affect	25
donor center	24
blood screening	24
previously shown	24
blood grouping	24
may serve	24
cells treated	24
supplementary table	24
two years	24
sample volume	24
igg antibody	24
mycobacterium tuberculosis	24
detection system	24
gastrointestinal disease	24
serological testing	24
immunosorbent assay	24
human blood	24
blood vessel	24
screening test	24
hiv infection	24
inflammatory cytokines	24
correlation coefficient	24
large scale	24
blood specimens	24
infected dogs	24
nonfarmworker families	24
currently available	24
cell type	24
pulmonary edema	24
canine astrovirus	24
significant decrease	24
six months	24
general anesthesia	24
membrane vesicles	24
cdna synthesis	24
ev numbers	24
cell migration	24
per unit	24
blood culture	24
diagnostic laboratory	24
metagenomic analysis	24
flow cell	24
small dogs	24
blood glucose	24
within minutes	23
skeletal muscle	23
light scattering	23
viral particles	23
studies will	23
ventricular septal	23
critically ill	23
data collection	23
ambient air	23
fatty acids	23
two weeks	23
significant reduction	23
pathogen detection	23
abo typing	23
thermal cycling	23
clinical settings	23
tissue culture	23
amino acids	23
consensus sequence	23
congestive heart	23
carbon monoxide	23
fold change	23
also may	23
care unit	23
exosomes isolated	23
hemoglobin levels	23
serum ferritin	23
microbial load	23
large numbers	23
management system	23
reactive samples	23
stranded dna	23
particles ml	23
gel electrophoresis	23
will provide	23
confirmed positive	23
platelet yield	23
microarray technology	23
creative commons	23
cell viability	23
acute diarrhoea	23
buffered saline	23
arachidonic acid	23
done using	23
durum wheat	23
donor deferral	23
prepared using	23
linked immunosorbent	23
thrombotic thrombocytopenic	23
exact test	23
long term	23
rhd beadchip	23
poorly understood	23
storage time	23
samples obtained	23
may represent	23
method using	23
mononuclear cells	23
genetic analysis	23
dna polymerase	23
handheld optical	23
study demonstrates	23
square test	23
surgical mask	23
mesenchymal stromal	23
transfusion associated	23
blood plasma	23
dependent manner	22
rhd typing	22
large volume	22
colorectal cancer	22
serial dilutions	22
may require	22
ev protein	22
gold nanoparticles	22
way anova	22
evs may	22
protein concentration	22
molecular mechanisms	22
genotyping results	22
authors declare	22
manual tube	22
single ev	22
two days	22
left atrial	22
samples containing	22
ev preparations	22
derived ev	22
nucleotide identity	22
samples per	22
hb content	22
cobe spectra	22
adipose tissue	22
marrow transplantation	22
high incidence	22
laboratory tests	22
different blood	22
posted june	22
retrospective review	22
investigate whether	22
national institute	22
trauma patients	22
rights reserved	22
disease severity	22
donated blood	22
risk assessment	22
serum tt	22
pool testing	22
bovine serum	22
patient population	22
platelet activation	22
outer membrane	22
specimen collection	22
null hypothesis	22
iron stores	22
tumour growth	22
based tests	22
study shows	22
bleeding patients	22
immune responses	22
light microscopy	22
predictive value	22
image processing	22
cell cultures	22
surface water	22
mayo clinic	22
nasal swabs	22
cardiovascular disease	22
water source	22
faecium ncimb	22
inflammatory bowel	22
collected using	22
group testing	22
rhd weak	22
buffy coats	22
cells using	21
allowed without	21
based amplification	21
treated rbcs	21
infected patients	21
many cases	21
based assay	21
antibody titers	21
protein levels	21
flow rate	21
serologic testing	21
quantitative pcr	21
hev rna	21
significant changes	21
quality improvement	21
data demonstrate	21
serum cobalamin	21
lupus erythematosus	21
respiratory viral	21
pooled sample	21
group systems	21
respiratory virus	21
repeated measures	21
prevalence rates	21
evs showed	21
using pcr	21
oral cavity	21
dried blood	21
blood flow	21
thrombocytopenic purpura	21
ev surface	21
broiler chickens	21
pulmonary artery	21
blood ordering	21
ae sd	21
pulse sensing	21
residual risk	21
two dogs	21
patient outcomes	21
better understanding	21
small rnas	21
electrochemical detection	21
platelet concentrate	21
medical research	21
without permission	21
biological material	21
bovine respiratory	21
contaminated water	21
time required	21
hazara virus	21
ev populations	21
patients compared	21
reference range	21
class ii	21
renal disease	21
antibody detection	21
may contribute	21
diagnostic tool	21
ev proteins	21
detection sensitivity	21
filter paper	21
within min	21
therapeutic potential	21
table i	21
sequence reads	21
follow procedures	21
low ferritin	21
host disease	21
lateral recumbency	21
laboratory results	21
detection rate	21
reuse allowed	21
study using	20
cytologic examination	20
patients treated	20
samples may	20
published data	20
control horses	20
rhd positive	20
deferral rates	20
microfluidic device	20
needle aspiration	20
university school	20
storage lesion	20
clostridium difficile	20
cells ml	20
renal function	20
european union	20
detection limit	20
affected samples	20
group antigen	20
sequence analysis	20
donor recruitment	20
readily available	20
cellular uptake	20
human metapneumovirus	20
clinical applications	20
relatively low	20
may play	20
rich plasma	20
closed system	20
exosome secretion	20
hla class	20
skin lesions	20
large evs	20
rhd variant	20
expression level	20
microfluidic devices	20
using blastn	20
first study	20
clinical studies	20
disease progression	20
reactive protein	20
pulmonary fibrosis	20
vena cava	20
cardiac surgery	20
resistive pulse	20
recent advances	20
four different	20
cross blood	20
new automated	20
glass slide	20
additional studies	20
posted april	20
direct rna	20
cell antigens	20
false negatives	20
chronic kidney	20
chlamydia trachomatis	20
hemoglobin level	20
blood spots	20
north carolina	20
extracted using	20
ovarian cancer	20
laboratory testing	20
cell lymphoma	20
febrile illness	20
cervical cancer	20
cd deficiency	20
great potential	20
tumour progression	20
zikv rna	20
also showed	20
times higher	20
canadian blood	20
dry hcqs	20
batrachochytrium salamandrivorans	20
cell concentrates	20
viral species	20
health issues	20
north america	20
dna microarrays	20
beckman coulter	20
low levels	20
recreational water	20
sample vf	20
acid sequence	20
systemic lupus	19
saharan africa	19
analytical sensitivity	19
normally distributed	19
urine testing	19
contact time	19
well known	19
insulin resistance	19
donor health	19
amplicon sequencing	19
lysis buffer	19
hcv rna	19
likely due	19
significantly improved	19
selection criteria	19
hiv positive	19
lung injury	19
post transfusion	19
bacterial cells	19
table shows	19
mammalian viruses	19
io catheter	19
hb level	19
potential biomarkers	19
developed countries	19
will also	19
teaching hospital	19
interstitial pneumonia	19
among different	19
differential diagnosis	19
patient identification	19
taken together	19
one dog	19
catheter insertion	19
different levels	19
surveillance system	19
common cause	19
sectional study	19
research institute	19
national institutes	19
also significantly	19
endemic areas	19
cycle threshold	19
high specificity	19
better understand	19
repeat testing	19
expression analysis	19
mirna expression	19
laboratory data	19
final concentration	19
negative pressure	19
emergency department	19
cd evs	19
indicator organisms	19
regular blood	19
mrna expression	19
ev detection	19
ev secretion	19
new donors	19
minion barcodes	19
low cost	19
routinely used	19
healthy horses	19
cell function	19
hla typing	19
key role	19
amplification reaction	19
large amounts	19
made using	19
potential role	19
conducted using	19
clinical sample	19
years ago	19
preliminary results	19
reactive results	19
apheresis donors	19
hospital blood	19
will enable	19
cancer progression	19
statistical analyses	19
limited settings	19
clinical respiratory	19
average number	19
axenic culture	19
epithelial cell	19
fold higher	19
extraction methods	19
different ev	19
platelet inventory	19
markers cd	19
amotosalen uva	19
two cases	19
automated blood	19
positive result	19
right ventricular	19
sensitive detection	18
storage conditions	18
healthy volunteers	18
significant number	18
routine use	18
pretransfusion testing	18
transfusion related	18
magnetic resonance	18
antibody positive	18
molecular analysis	18
rbc unit	18
cell count	18
probiotic bacterium	18
dtt treatment	18
health dynamics	18
hydration water	18
pooled platelet	18
free water	18
reagent red	18
total evs	18
differential expression	18
two methods	18
health system	18
computed tomography	18
bacterial pathogens	18
several times	18
positive test	18
genome coverage	18
cell death	18
ev size	18
virus sequences	18
com scientificreports	18
nasal swab	18
based method	18
architect i	18
apheresis procedures	18
respiratory panel	18
white matter	18
supervised learning	18
sample type	18
using standard	18
without compromising	18
molecular methods	18
avian influenza	18
cd cell	18
ev biogenesis	18
raman spectroscopy	18
total blood	18
reads per	18
associated proteins	18
study included	18
genetic material	18
next step	18
histologic sections	18
microbiologic study	18
healthy adult	18
complex samples	18
state university	18
antibody titer	18
tube testing	18
institutional review	18
oxford nanopore	18
temporal mental	18
plasma transfusion	18
healthy cats	18
infectious peritonitis	18
current methods	18
spike protein	18
i ii	18
pathogenic viruses	18
data indicate	18
assay time	18
screening tool	18
plasmodium falciparum	18
per patient	18
enzyme activity	18
rhd exon	18
purified evs	18
viral nucleic	18
study aims	18
viral titers	18
hcqs sample	18
tumour cell	18
different methods	18
aortic arch	18
serum concentrations	18
previous study	18
several studies	18
bacterial infections	18
competing interests	18
hematology analyzer	18
antibiotic resistance	18
sample pools	18
msc evs	18
hiv ag	18
rhd variants	18
significant antibodies	18
internal control	18
much lower	18
culture results	18
low level	18
ag ab	18
previously published	18
positive dat	18
feline infectious	18
many different	18
hyperthyroid cats	18
data showed	18
respiratory infection	18
antibody tests	18
drug administration	18
cell wall	17
molecular basis	17
fluorescence microscopy	17
enteric disease	17
platelet additive	17
transport media	17
copies per	17
positive antibody	17
plasma concentrations	17
blood smear	17
delayed hemolytic	17
review board	17
controlled trial	17
triple negative	17
sequencing using	17
genetic diversity	17
wt mice	17
data set	17
sample matrix	17
dendritic cells	17
ev uptake	17
study evaluated	17
early diagnosis	17
i sr	17
direct pcr	17
rejuvenation solution	17
spiked samples	17
ev samples	17
size range	17
three years	17
endotracheal tube	17
ordered hydrated	17
test samples	17
studies using	17
cmv igg	17
may suggest	17
healthy subjects	17
viral transport	17
pcr tests	17
clinical relevance	17
higher levels	17
consecutive days	17
adverse outcomes	17
cell evs	17
crucial role	17
hospital background	17
ae ml	17
detection using	17
one unit	17
antigen tests	17
samples compared	17
hemolytic uremic	17
evs secreted	17
forming units	17
data obtained	17
ml min	17
water molecules	17
irradiated blood	17
three times	17
increased levels	17
rh blood	17
similar results	17
clinical diagnostic	17
study group	17
throat swabs	17
electron microscopic	17
health status	17
virus type	17
tract disease	17
oral administration	17
one another	17
blood smears	17
buffered formalin	17
respiratory diseases	17
herpes simplex	17
pathway analysis	17
time consuming	17
screening tests	17
plasma using	17
low prevalence	17
small sample	17
using rt	17
iron overload	17
collect samples	17
pcr primers	17
characterized using	17
direct naats	17
cell cycle	17
target species	17
gradient ultracentrifugation	17
low sensitivity	17
tangential flow	17
signalling pathways	17
flow filtration	17
sampling methods	17
allogeneic blood	17
culture conditions	17
stored rbcs	17
group received	17
quality management	17
novel viruses	17
rna samples	17
simultaneous detection	17
cell activation	17
prosthetic repair	17
brain barrier	17
middle east	17
wbc count	17
also identified	17
transfusion testing	17
new england	17
different cell	17
three months	17
recent study	17
leucocyte depleted	17
nucleotide polymorphisms	17
donor blood	17
anaplasma phagocytophilum	17
immunoassay cassette	17
pig farmer	17
may indicate	17
guano samples	17
immune cell	17
transfusion center	17
condition score	17
leading cause	17
antigen typing	17
antibody screens	17
blood banking	17
amplification process	17
blood gas	17
replacement therapy	17
serum creatinine	17
cold storage	17
positive donors	16
rare blood	16
poor prognosis	16
observational study	16
antibody avidity	16
six healthy	16
gene deletion	16
blood derived	16
factor viii	16
detection method	16
prepare roentgenograms	16
alkaline phosphatase	16
survival time	16
purified using	16
wide variety	16
binding sites	16
component analysis	16
nat screening	16
clinical disease	16
rhd diiia	16
fresenius kabi	16
genome copies	16
pluripotent stem	16
sequencing approach	16
waterborne disease	16
wore masks	16
nasal discharge	16
supplementary material	16
gel cards	16
one hour	16
rna extracted	16
high expression	16
cell derived	16
blood agar	16
product utilization	16
negative breast	16
exosome isolation	16
least two	16
evs using	16
mott cross	16
will allow	16
rbc alloantibodies	16
record weight	16
cystic fibrosis	16
using high	16
different concentrations	16
therapeutic effect	16
enteric viruses	16
biopsy samples	16
synovial fluid	16
rbc alloimmunization	16
evs containing	16
days prior	16
heavy metal	16
adverse event	16
leucine codon	16
allele frequencies	16
iron status	16
rna molecules	16
concept study	16
volume reduction	16
regenerative medicine	16
test kits	16
surface antigen	16
rbc exchange	16
affected horses	16
virus infections	16
samples contained	16
supply chain	16
lung tissue	16
atomic force	16
breast milk	16
transfusion support	16
dust period	16
tested negative	16
predicted phenotype	16
additional file	16
circulating extracellular	16
new method	16
processing time	16
significant correlation	16
mass index	16
pancreatic cancer	16
san diego	16
marrow aspiration	16
small amounts	16
severe disease	16
improve patient	16
close contact	16
units per	16
using differential	16
nonfarmworker sample	16
clinical presentation	16
short time	16
income countries	16
rbcs stored	16
commonly found	16
microarray data	16
young children	16
amr genes	16
shar peis	16
clinical outcome	16
hbv infection	16
current state	16
uremic syndrome	16
respiratory specimens	16
myocardial infarction	16
viral targets	16
human platelet	16
standard operating	16
rhd alleles	16
contigs assigned	16
blood bags	16
expression patterns	16
series classification	16
gi disease	16
clinical use	16
rapid diagnostic	16
filtration efficiency	16
incubation time	16
feline coronavirus	16
different stages	16
secondary electron	16
national university	16
also determined	16
viral target	16
log ml	16
donor safety	16
mean number	16
testing using	16
donor plasma	16
pathogen reduced	16
much less	16
assess whether	16
controlled trials	16
feature learning	16
well suited	15
time intervals	15
chronic inflammation	15
mini kit	15
dna sequences	15
pcr master	15
jugular vein	15
largely unknown	15
dynamic light	15
coronary arteries	15
experimental data	15
two species	15
sample volumes	15
identified using	15
spinal canal	15
quantitative real	15
liquid nitrogen	15
generated using	15
farmworker sample	15
ev research	15
pcr test	15
sequencing technologies	15
care diagnostics	15
causative agent	15
lavage fluid	15
faecal viromes	15
glass slides	15
must also	15
clinically important	15
blood mononuclear	15
many countries	15
west africa	15
healthcare workers	15
sample sizes	15
seven days	15
predicted locations	15
saliva samples	15
lung disease	15
potential risk	15
laboratory information	15
pcr results	15
cd monoclonal	15
old male	15
activation energy	15
based approach	15
increased expression	15
human pathogens	15
ev quantification	15
may vary	15
relative abundances	15
higher number	15
wastewater workers	15
detection range	15
positive patients	15
nucleotide polymorphism	15
routine diagnostic	15
ms analysis	15
abdominal cavity	15
foreign body	15
pcr reactions	15
small ev	15
rapid identification	15
blood stem	15
gradient centrifugation	15
timely manner	15
case definition	15
rbc products	15
blood processing	15
standard tube	15
water bath	15
data sets	15
biological activity	15
type unspecified	15
limited number	15
positive correlation	15
thrombus formation	15
novo assembly	15
id rhd	15
carlo simulation	15
unaffected samples	15
force microscopy	15
random hexamers	15
world samples	15
autoimmune hemolytic	15
fluorescence detection	15
ev treatment	15
pcr testing	15
national cancer	15
vivo studies	15
operatory surfaces	15
days later	15
based blood	15
viral diversity	15
donor return	15
per cell	15
normal rhd	15
saline solution	15
bacterial evs	15
cell counts	15
rhd xt	15
first two	15
surface plasmon	15
clinical evaluation	15
donor retention	15
human urine	15
intranasal administration	15
using either	15
pulmonary valve	15
dna analysis	15
literature review	15
autopsy procedures	15
two patients	15
well established	15
probe sets	15
response rate	15
human cd	15
fluorescent dyes	15
clinical impact	15
full genome	15
significant effect	15
water sources	15
situ hybridization	15
evidence based	15
two types	15
brain stem	15
imaging flow	15
hla antibody	15
plant viruses	15
amplification assay	15
see note	15
platelet antigens	15
hb deferral	15
type diabetes	15
tpe procedures	15
displacement amplification	15
low dose	15
evs produced	15
high concentration	15
gene sequencing	15
ev concentration	15
data samples	15
small cell	15
centrifugal microfluidic	15
human coronavirus	15
different isolation	15
patients requiring	15
south africa	15
viral proteins	15
dna damage	15
sudden death	15
signalling pathway	15
miseq sequencing	15
incubation periods	15
slightly lower	15
transfusion guidelines	15
data points	15
methyl groups	15
microfluidic systems	15
test sample	15
well plates	15
past years	15
adult cats	15
progenitor cell	15
canine parvovirus	15
correlation among	15
biological fluids	15
ferritin testing	15
pcr using	15
new approach	15
frequently used	15
respiratory distress	15
slightly higher	15
specific markers	15
mast cells	15
cd exo	15
case study	15
antibody test	15
neg rbc	14
day post	14
free plasma	14
showed significant	14
using spss	14
may reflect	14
nucleotide sequences	14
mitral valves	14
two units	14
cell collection	14
newly developed	14
cell antibodies	14
single donor	14
routine blood	14
surface protein	14
rna virus	14
also detected	14
multiplex real	14
replacement fluid	14
normal saline	14
dna sequence	14
new blood	14
liver biopsy	14
bacterial community	14
single unit	14
human brain	14
chloroquine phosphate	14
ionized calcium	14
cancer institute	14
dna microarray	14
virus genome	14
platelet cd	14
clinical diagnostics	14
reaction mixture	14
sampling results	14
typing results	14
fda approved	14
cardiac disease	14
tube methods	14
comparator assay	14
regression models	14
acute kidney	14
african american	14
relatively small	14
cell antibody	14
medical care	14
emergency release	14
fungal infections	14
results indicated	14
standard methods	14
iv iron	14
htlv i	14
previously identified	14
positive controls	14
control sample	14
antigen negative	14
decision making	14
hepatocellular carcinoma	14
obese dogs	14
procedures performed	14
proteomic profiling	14
hong kong	14
patient received	14
healthy individuals	14
genetic variants	14
protective equipment	14
acquired immunodeficiency	14
nat yield	14
blood testing	14
stored platelets	14
component preparation	14
also demonstrated	14
clinical cases	14
sample pretreatment	14
deferral rate	14
abo genotyping	14
gel card	14
phosphate buffered	14
control study	14
connective tissue	14
plt count	14
lower concentrations	14
useful tool	14
respiratory illness	14
drug delivery	14
allogeneic donors	14
ml syringe	14
data suggests	14
environmental conditions	14
away time	14
donor program	14
thawed plasma	14
volume processed	14
rna sequences	14
storage duration	14
well plate	14
western blots	14
month deferral	14
labelled evs	14
group ab	14
reads aligning	14
microarray analysis	14
data management	14
different regions	14
chemical composition	14
laser scanning	14
brain tissue	14
recently demonstrated	14
rrna gene	14
regular donors	14
sample introduction	14
comparative analysis	14
gis gps	14
taxonomic profiles	14
single sample	14
transfusion strategies	14
west nile	14
target sequence	14
venous blood	14
emergency blood	14
mycoplasma spp	14
rna library	14
prevalence antigen	14
risk management	14
copy numbers	14
medical history	14
strand displacement	14
iron metabolism	14
dg gel	14
often used	14
assay kit	14
molecular typing	14
right ventricle	14
one case	14
quantitative analysis	14
gauge needle	14
statistical difference	14
study provides	14
septic transfusion	14
negative rbcs	14
training period	14
circulatory overload	14
two distinct	14
study showed	14
cell adhesion	14
gram stain	14
amniotic fluid	14
integrated microfluidic	14
image analysis	14
available data	14
incidence rate	14
significant impact	14
study suggests	14
method used	14
flow strips	14
positive rate	14
evaluate whether	14
split rate	14
one month	14
united kingdom	14
bone metastasis	14
major role	14
sample testing	14
adult patients	14
recurrent group	14
sampling method	14
typhoid fever	14
none required	14
pcr method	14
ev yield	14
early stage	14
stranded rna	14
sterile saline	14
biothreat agents	14
rbc antigens	14
highly variable	14
cognitive impairment	14
based transfusion	14
irradiated rbcs	14
pcr positive	14
colony forming	14
microfluidic platform	14
treatment groups	14
opportunistic pathogens	14
pivotal role	14
clinical laboratory	14
training set	14
clinical diagnosis	14
donating blood	14
microbial communities	14
mirna cargo	14
genetic testing	14
water bodies	14
blood systems	14
cost savings	14
phase contrast	14
study demonstrated	14
amplification method	14
human medicine	14
take place	14
cells expressing	14
sample collected	14
differential abundance	14
different sources	14
igg antibodies	13
casein micelles	13
chronically transfused	13
database using	13
low number	13
among patients	13
studies showed	13
caudal cranial	13
methionine codon	13
poc devices	13
supplementary file	13
stool sample	13
critical role	13
independently associated	13
see disease	13
kernel density	13
clinical features	13
mean hb	13
overall survival	13
magnetic force	13
molecular cargo	13
cells kg	13
ev released	13
compatibility testing	13
classified using	13
lactate levels	13
acid test	13
fluorescently labelled	13
known viruses	13
strongly associated	13
maternal plasma	13
help us	13
using nanoparticle	13
based dna	13
genetic variation	13
highly expressed	13
biodefense applications	13
copy number	13
shotgun sequencing	13
primary care	13
healthcare system	13
panel cells	13
arterial blood	13
another study	13
total population	13
specific gravity	13
lower risk	13
times per	13
virus rna	13
six sigma	13
positive specimens	13
blood supplier	13
differentially abundant	13
dna testing	13
platelet recovery	13
bioaerosol exposure	13
genome amplification	13
chronic disease	13
ap activity	13
random sampling	13
antitrypsin deficiency	13
abo discrepancy	13
without agitation	13
virus species	13
evs compared	13
simplex virus	13
log reduction	13
preoperative anemia	13
fetal rhd	13
cross match	13
basic anomaly	13
training samples	13
i will	13
strand synthesis	13
personal protective	13
quality indicators	13
host cell	13
patients without	13
pregnant woman	13
rural areas	13
comparative study	13
trauma center	13
pooling strategy	13
small size	13
total volume	13
left ventricle	13
duke university	13
complex biological	13
rh antigens	13
several different	13
small intestine	13
viral respiratory	13
health effects	13
drug abuse	13
five different	13
clinical course	13
emergency use	13
european countries	13
aortic valve	13
sequencing run	13
less likely	13
human respiratory	13
short period	13
normal horses	13
provide information	13
continuous flow	13
autopsy room	13
null phenotype	13
significantly less	13
biopsy punch	13
high viral	13
operating procedures	13
small volumes	13
principal component	13
screening assays	13
high cost	13
great ape	13
one group	13
rna cargo	13
acute pancreatitis	13
vox sanguinis	13
heme iron	13
platelet components	13
pulmonary arteries	13
salmonella sp	13
entire genome	13
phase i	13
second step	13
detected using	13
plasma concentration	13
platelet concentration	13
deep learning	13
findings indicate	13
factors associated	13
cell processor	13
water sample	13
using anti	13
laboratory staff	13
isothermal nucleic	13
human tissues	13
cost effective	13
low titer	13
highest number	13
transfusion laboratory	13
donor unit	13
rh phenotype	13
vasovagal reactions	13
dna viruses	13
health agencies	13
ko mice	13
england biolabs	13
proteomics data	13
cranial fossa	13
exosomal rna	13
well tolerated	13
adult dogs	13
plastic bags	13
alloimmunized patients	13
see section	13
expression data	13
retrospective cohort	13
active metabolite	13
sevs isolated	13
increased significantly	13
south korea	13
transfusion sample	13
allergic reactions	13
membrane proteins	13
normal cats	13
plasmon resonance	13
cells may	13
enzymatic amplification	13
infective endocarditis	13
biological processes	13
first report	13
cell populations	13
standard lateral	13
barr virus	13
five years	13
specific primer	13
variant alleles	13
clerical errors	13
various types	13
central blood	13
around time	13
disease patients	13
animal models	13
end reads	13
donation frequency	13
window predictions	13
authors report	13
among first	13
unsupervised anomaly	13
squamous cell	13
negative donors	13
molecular assays	13
breed dogs	13
amplification technologies	13
adverse reaction	13
platelet storage	13
patient sample	13
human papillomavirus	13
transplant recipients	13
neural networks	13
methylene blue	13
allowed us	13
months post	13
member states	13
significant proportion	13
clinical real	13
heavy metals	13
flow cells	13
domestic animals	13
clot formation	13
study also	13
like illness	13
therapeutic target	13
high degree	13
prbc units	13
diagnostic assay	13
commons attribution	13
remained stable	13
genetic data	13
adult foxes	13
species identification	13
enveloped viruses	13
tof ms	13
intestinal tract	13
flow rates	13
decreased significantly	13
coagulation parameters	13
raman spectra	12
posted september	12
current status	12
term storage	12
reverse type	12
omeprazole treatment	12
ab plasma	12
great apes	12
viral titer	12
dissection techniques	12
immature platelet	12
east respiratory	12
acute lung	12
may therefore	12
lymphocyte count	12
airway obstruction	12
tap water	12
liver failure	12
kidney injury	12
photochemical treatment	12
induced pluripotent	12
echinococcus granulosus	12
surface proteins	12
associated protein	12
transfusion transmission	12
error rate	12
one hand	12
additional information	12
using nanopore	12
ribosomal rna	12
based testing	12
rna sequence	12
titer results	12
effective treatment	12
remains unknown	12
proteomics analysis	12
polyethylene glycol	12
swarm detection	12
buccal swab	12
pcr system	12
plasma sample	12
prospective cohort	12
extraction method	12
lifestyle factors	12
also compared	12
bacterial strains	12
detection dogs	12
also included	12
immunohematology reference	12
direct detection	12
cytokine production	12
biomedical research	12
negative pregnant	12
surgical procedures	12
tranexamic acid	12
environmental samples	12
among data	12
using commercial	12
ferritin ng	12
host immune	12
vesicles introduction	12
abo discrepancies	12
exosomal markers	12
muscle cells	12
biomarker discovery	12
minion sequencer	12
rbc storage	12
chagas disease	12
ev characterization	12
gene ontology	12
ev concentrations	12
blood establishments	12
software version	12
last decade	12
oxygen species	12
blood utilization	12
related adverse	12
high numbers	12
liver transplantation	12
crispr cas	12
virus genomes	12
soft tissues	12
recursive method	12
frequently detected	12
true positive	12
may become	12
cd count	12
san francisco	12
based test	12
following treatment	12
rbc blood	12
fever virus	12
rh typing	12
coding rnas	12
enzyme immunoassay	12
part ii	12
total ev	12
testing laboratory	12
cell membrane	12
data may	12
plasma volume	12
nosocomial transmission	12
fluorescence intensity	12
air sampling	12
zeta potential	12
also present	12
tapestry pooling	12
batrachochytrium dendrobatidis	12
publicly available	12
platelet loss	12
test food	12
cell growth	12
urea nitrogen	12
five days	12
sample pool	12
cytometry analysis	12
large volumes	12
results also	12
muscular dystrophy	12
post collection	12
blood collected	12
recombinase polymerase	12
thermo scientific	12
wastewater treatment	12
samples will	12
engineered evs	12
first months	12
without clinical	12
incidence rates	12
upper limit	12
polymerase amplification	12
dat positive	12
much greater	12
interquartile range	12
diatom species	12
cmnc protocol	12
health problem	12
abbott alinity	12
pcr detection	12
five samples	12
risks associated	12
viral peptides	12
autoimmune diseases	12
dogs received	12
laboratory operations	12
powerful tool	12
detection module	12
log iu	12
transfused units	12
treatment group	12
nile virus	12
big data	12
reportable disease	12
specific ev	12
may influence	12
adverse transfusion	12
weeks later	12
pneumatic tube	12
second sample	12
three methods	12
allele frequency	12
collection time	12
diffuse alveolar	12
dna using	12
one positive	12
higher sensitivity	12
abdominal wall	12
several days	12
nitric oxide	12
testing method	12
exosomal mirna	12
particle analysis	12
three dogs	12
alcohol concentration	12
post thaw	12
molecular changes	12
high accuracy	12
microscope slide	12
widely available	12
infected cats	12
potential sources	12
patient management	12
tissue factor	12
one day	12
fluorescent signal	12
management systems	12
basecalling model	12
patient plasma	12
streptococcus pneumoniae	12
accession numbers	12
sequencing technology	12
cell lung	12
clinical manifestations	12
care hospital	12
estimated using	12
body temperature	12
parental cells	12
one donor	12
stomach tube	12
ev analysis	12
diagnostic procedures	12
oral contamination	12
murine macrophages	12
randomly assigned	12
cells showed	12
immunodeficiency syndrome	12
rna input	12
alert level	12
novel method	12
broad range	12
sewage samples	12
clinical laboratories	12
specific proteins	12
alpha diversity	12
ae standard	12
quality assessment	12
nanopore reads	12
sputum samples	12
serum sample	12
direct amplification	12
exosome markers	12
health workers	12
water supplies	12
jaccard distance	12
prediction error	12
tests performed	12
johns hopkins	12
nt database	12
rare donors	12
virus circulation	12
individual sample	12
clinical information	12
regression model	12
community transmission	12
phase ii	12
owned dogs	12
unlabeled data	12
ductal artery	12
research laboratory	12
pcr based	12
preparation methods	12
rhd exons	12
older adults	12
neurodegenerative diseases	12
nanopore metagenomic	12
testing methods	12
specific detection	12
assay using	12
central venous	12
beneficial effects	12
negative result	12
clinical decision	12
healthy control	12
average cellularity	12
immucor neo	12
cell debris	12
pd patients	12
wb units	12
give blood	12
scattering cross	12
dental operatory	12
clinical utility	12
working group	12
recovery medium	12
cobalamin deficiency	12
reference sequences	12
academic medical	12
aplastic anemia	12
hydrated sample	12
mirasol prt	12
carbon dioxide	12