bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
acute respiratory	8874
intensive care	8199
coronavirus disease	6711
critically ill	6408
risk factors	6163
novel coronavirus	5802
respiratory syndrome	5148
mechanical ventilation	4930
severe acute	4805
ill patients	4765
health care	4752
care unit	4685
respiratory distress	4148
stem cell	3912
mg kg	3777
severe covid	3629
respiratory failure	3430
mean age	3303
distress syndrome	3290
systematic review	3279
bone marrow	3248
clinical characteristics	3148
control group	3105
cancer patients	3012
hospitalized patients	2955
significantly higher	2949
one patient	2886
cord uid	2876
doc id	2876
clinical trials	2851
septic shock	2784
cohort study	2763
united states	2714
critical care	2708
blood pressure	2663
respiratory tract	2605
increased risk	2599
two groups	2582
high risk	2525
statistically significant	2507
cell transplantation	2495
patients admitted	2482
significant difference	2417
heart failure	2414
syndrome coronavirus	2397
mortality rate	2365
median age	2350
among patients	2291
peripheral blood	2277
public health	2244
clinical features	2230
immune response	2229
patients received	2197
case report	2193
emergency department	2179
two patients	2121
clinical trial	2093
adverse events	2083
infectious diseases	2057
years old	2032
risk factor	2032
patients treated	2028
clinical practice	2013
ng ml	1999
mg dl	1975
lung injury	1967
retrospective study	1953
patients undergoing	1930
acquired pneumonia	1913
lung cancer	1867
side effects	1865
may also	1851
patients receiving	1845
adult patients	1824
significant differences	1811
patients without	1805
infection control	1805
breast cancer	1804
clinical course	1771
controlled trial	1765
renal failure	1727
icu admission	1704
case series	1684
cytokine storm	1683
infected patients	1681
observational study	1673
lung disease	1628
computed tomography	1621
organ failure	1605
immune system	1602
logistic regression	1593
present study	1588
world health	1583
informed consent	1571
diabetes mellitus	1560
performed using	1553
patients infected	1545
epithelial cells	1543
icu patients	1540
university hospital	1528
hospital stay	1525
inflammatory response	1501
randomized controlled	1501
ct scan	1498
hospital mortality	1493
pulmonary disease	1477
health organization	1458
disease severity	1444
higher risk	1443
reactive protein	1430
viral infections	1429
nervous system	1411
myocardial infarction	1407
hematopoietic stem	1404
stem cells	1392
clinical outcomes	1390
patients may	1375
overall survival	1362
heart disease	1346
least one	1345
pg ml	1336
respiratory symptoms	1335
three patients	1332
viral load	1332
severe disease	1330
prospective study	1329
chest ct	1327
cardiac arrest	1317
significantly lower	1316
patient care	1316
transplant recipients	1314
liver disease	1310
pediatric patients	1306
rights reserved	1302
viral infection	1299
whole blood	1290
cardiovascular disease	1277
flow cytometry	1259
differential diagnosis	1252
cd cd	1252
virus infection	1247
blood transfusion	1241
blood donors	1235
blood flow	1227
cystic fibrosis	1211
gene expression	1207
pulmonary embolism	1207
renal function	1204
healthcare workers	1199
factors associated	1199
retrospective cohort	1199
chain reaction	1191
lymph nodes	1185
care units	1180
study period	1178
convalescent plasma	1177
important role	1177
protective equipment	1176
coronary artery	1172
heart rate	1167
converting enzyme	1165
elderly patients	1163
staphylococcus aureus	1159
polymerase chain	1157
hospital admission	1154
lung function	1152
general population	1152
disease control	1150
four patients	1147
chronic obstructive	1145
statistical analysis	1140
lymph node	1140
middle east	1137
cell lines	1132
median time	1131
patients underwent	1129
rheumatoid arthritis	1125
new york	1124
blood samples	1120
red blood	1118
liver failure	1115
primary care	1110
blood cell	1101
endothelial cells	1101
infectious disease	1100
adverse effects	1098
previous studies	1097
oxygen saturation	1089
signifi cant	1087
nk cells	1086
within days	1075
personal protective	1071
brain injury	1070
cd cells	1070
clinical data	1070
severe sepsis	1068
long term	1066
obstructive pulmonary	1065
multivariate analysis	1061
type diabetes	1061
platelet count	1057
five patients	1055
severe cases	1046
body weight	1044
kidney injury	1044
replacement therapy	1036
abdominal pain	1036
consecutive patients	1035
mental health	1035
medical center	1032
study design	1031
coronavirus pneumonia	1028
antibiotic therapy	1028
critical illness	1016
clinical presentation	1016
east respiratory	1013
urinary tract	1010
sample size	1001
physical examination	992
acute kidney	992
cardiac surgery	991
acute lung	990
medical records	988
clinical manifestations	987
blood cells	986
liver transplantation	983
magnetic resonance	982
immune responses	979
associated pneumonia	974
nucleic acid	970
positive patients	968
inflammatory cytokines	968
ischemic stroke	964
pregnant women	959
care workers	944
regression analysis	943
within hours	937
hand hygiene	935
central nervous	934
mechanically ventilated	932
lower respiratory	930
clinical symptoms	927
confirmed covid	926
mortality rates	925
ml kg	923
tract infections	921
significantly increased	919
type i	918
influenza virus	917
poor prognosis	915
may lead	915
data suggest	914
patients hospitalized	913
trauma patients	913
disease progression	913
kidney disease	912
organ dysfunction	905
year old	904
host disease	902
patients presenting	899
prostate cancer	895
lopinavir ritonavir	895
growth factor	893
patients showed	891
author funder	880
apache ii	878
granted medrxiv	877
study group	877
many patients	876
included patients	876
retrospective analysis	872
copyright holder	871
family members	870
median follow	869
upper respiratory	868
one case	868
left ventricular	868
icu stay	866
chronic hepatitis	864
healthy controls	862
results suggest	860
symptom onset	860
commonly used	859
case reports	857
significantly associated	855
multiple organ	850
nitric oxide	849
inclusion criteria	849
old male	848
venous thromboembolism	848
body mass	847
randomized clinical	847
respiratory rate	846
predictive value	843
membrane oxygenation	840
atrial fibrillation	839
day mortality	838
risk patients	837
ml min	836
patients requiring	831
coronavirus infection	828
data collection	825
tract infection	823
clinical signs	822
myocardial injury	819
determine whether	819
imaging findings	817
per day	817
signifi cantly	817
high levels	815
extracorporeal membrane	813
necrosis factor	813
free survival	811
six patients	809
significant increase	809
may occur	805
controlled trials	803
high mortality	801
multiple sclerosis	797
blood products	796
fi ndings	793
social distancing	791
acute gvhd	789
central venous	787
pao fio	785
sickle cell	783
mass index	782
invasive ventilation	781
pilot study	780
age years	779
kg day	777
older adults	774
one year	774
primary outcome	773
chronic gvhd	773
conditioning regimen	770
patient population	768
patients died	766
clinical outcome	765
weight loss	763
operating room	762
respiratory disease	752
monoclonal antibody	751
pulmonary hypertension	751
respiratory viruses	751
oxidative stress	750
blood group	744
significantly reduced	744
significantly different	742
respiratory infections	741
white blood	741
colorectal cancer	739
patients developed	737
may result	735
minimally invasive	733
serum levels	733
two cases	730
medical history	729
fi rst	727
clinical studies	726
patients will	726
cardiac output	721
acute phase	721
tumor necrosis	721
chest pain	718
confirmed cases	716
cell count	714
red cell	711
may cause	710
blood loss	710
soft tissue	709
design method	707
oxygen therapy	706
bronchoalveolar lavage	705
ventilated patients	705
innate immune	703
viral rna	703
respiratory syncytial	702
recent studies	702
liver function	701
odds ratio	699
arterial blood	699
confidence interval	699
widely used	697
hong kong	697
older patients	696
analysis showed	695
national health	693
pulmonary function	693
renal replacement	692
old female	691
even though	686
authors declare	686
pulmonary fibrosis	684
high dose	683
version posted	682
age group	679
severe pneumonia	677
study showed	675
clinical management	675
statistical significance	674
syncytial virus	674
respiratory infection	674
seven patients	672
peer review	669
poor outcome	667
cardiac injury	667
immunocompromised patients	666
spinal cord	666
smooth muscle	664
severe patients	664
viral pneumonia	664
palliative care	663
early diagnosis	663
ct scans	662
may help	660
cell carcinoma	660
pseudomonas aeruginosa	659
blood components	659
patients presented	652
electron microscopy	651
image quality	646
higher mortality	646
artery disease	646
antibiotic treatment	645
total number	645
renal disease	644
year period	644
test results	643
treated patients	642
clinical improvement	641
medical care	641
blood glucose	640
blood cultures	639
identifi ed	638
immune cells	636
cytokine release	636
well tolerated	635
recent study	635
first case	634
increased mortality	633
blood donation	632
prospective cohort	631
eight patients	631
invasive mechanical	630
normal range	629
bacterial infection	629
cord blood	629
first time	629
large number	627
old man	627
pulmonary artery	627
physical activity	626
patients diagnosed	625
incubation period	625
several studies	625
serum creatinine	624
cell proliferation	623
multiple myeloma	623
tidal volume	623
bacterial infections	622
care providers	621
extracellular vesicles	621
may contribute	621
resonance imaging	620
gastrointestinal tract	619
gold standard	619
surgical procedures	616
patient safety	614
pleural effusion	614
previously reported	614
results showed	613
infected pneumonia	610
medical staff	609
hospital discharge	609
supportive care	609
combination therapy	608
outcome measures	606
early stage	605
nk cell	601
acute renal	601
decision making	600
significant reduction	599
standard deviation	599
severe respiratory	597
type ii	595
single center	594
pet ct	594
per patient	594
vital signs	593
small bowel	592
sars coronavirus	592
liver injury	591
mg ml	591
mm hg	590
ethics committee	590
monoclonal antibodies	590
randomized trial	589
traumatic brain	588
mg day	588
patients aged	588
chronic kidney	587
measured using	587
univariate analysis	585
prognostic factors	585
allogeneic hematopoietic	585
intravenous immunoglobulin	584
made available	584
body temperature	583
laboratory tests	583
average age	581
one study	581
laboratory findings	581
cell line	580
recent years	580
american college	576
marrow transplantation	576
ct findings	576
per year	575
study population	575
lupus erythematosus	574
two different	574
summary conclusion	573
fatality rate	572
exclusion criteria	570
old woman	570
amino acid	570
hepatocellular carcinoma	569
also found	568
hbv dna	568
antiviral therapy	567
preliminary results	567
metabolic syndrome	565
last years	565
data analysis	564
diagnostic criteria	561
cell transplant	559
cumulative incidence	558
older age	557
dendritic cells	557
nosocomial infections	557
disseminated intravascular	557
case studies	556
acute myocardial	555
wide range	555
surgical treatment	554
septic patients	554
survival rate	552
treatment options	552
intravascular coagulation	552
systemic lupus	552
descriptive study	551
health system	550
healthcare professionals	549
pulmonary edema	549
healthy volunteers	549
higher levels	548
high incidence	547
inflammatory markers	547
month period	545
respiratory support	545
time pcr	543
tumor cells	543
care medicine	543
may play	542
sore throat	542
literature review	542
another study	542
independently associated	541
tested positive	541
sofa score	541
ebola virus	540
emergency room	539
independent risk	539
high prevalence	538
chest radiograph	537
cov infection	537
treatment group	537
diabetic patients	536
arterial pressure	534
animal models	534
antimicrobial therapy	533
mr imaging	532
new coronavirus	532
regression model	532
patients suffering	531
continuous variables	531
retrospective review	530
streptococcus pneumoniae	529
common cause	528
complete remission	528
nine patients	525
kidney transplant	524
chart review	524
surgical intervention	524
effective treatment	524
age groups	523
sars patients	523
observational studies	522
task force	522
inflammatory bowel	521
cell death	521
current study	521
mononuclear cells	521
infl ammatory	520
endotracheal intubation	519
negative pressure	518
three groups	518
severely ill	516
clinically significant	516
tertiary care	515
lung transplantation	515
randomised controlled	514
twice daily	514
allogeneic stem	514
cell surface	514
may provide	513
surgical patients	511
will also	510
low risk	509
patient outcomes	508
supplemental oxygen	506
hiv infection	506
prone positioning	506
airway pressure	505
first days	505
learning objectives	505
transplant patients	504
lymphocyte count	503
clinical findings	502
early detection	500
machine learning	500
study aimed	499
aged years	499
blood gas	499
study included	497
allergic rhinitis	497
autoimmune diseases	497
patients included	497
family history	496
summary conclusions	496
acute care	496
time points	494
protein expression	494
interquartile range	494
analyzed using	493
asymptomatic patients	493
insulin resistance	493
virus disease	492
two weeks	491
control study	491
lung tissue	491
significantly decreased	490
disease activity	490
categorical variables	490
small number	488
baseline characteristics	488
function tests	487
blood bank	487
infection prevention	487
mental status	487
interstitial lung	487
practice guidelines	487
medrxiv preprint	486
real time	486
bowel disease	485
venous thrombosis	485
plasma levels	485
molecular weight	484
white matter	484
prospective observational	484
chronic liver	484
cancer cells	483
nasal cannula	483
may require	482
significant correlation	482
bacterial pneumonia	482
background case	481
infl ammation	480
results indicate	480
clinically relevant	480
previously described	479
overall mortality	478
viral replication	478
high level	478
control measures	478
diagnostic accuracy	478
findings suggest	477
united kingdom	476
significant improvement	476
release syndrome	476
mrna expression	475
may increase	474
assessed using	473
multicenter study	473
related mortality	473
gastrointestinal symptoms	472
exact test	472
higher incidence	471
cell activation	470
natural killer	470
young children	470
western blot	470
low dose	469
cognitive impairment	469
lactate dehydrogenase	469
china clinical	468
phase ii	468
analysis revealed	467
obese patients	467
patient characteristics	466
subarachnoid hemorrhage	465
ex vivo	465
see table	464
escherichia coli	464
endothelial cell	464
electronic medical	463
infectious complications	462
solid organ	461
significant decrease	461
international license	460
patient developed	460
healthcare system	460
general hospital	459
will need	459
fungal infections	458
systemic inflammation	458
three months	458
patients compared	458
systemic inflammatory	457
postoperative complications	457
congenital heart	457
future studies	457
endothelial dysfunction	456
class i	456
diffuse alveolar	455
mesenchymal stem	455
sectional study	454
right ventricular	453
positive results	453
vein thrombosis	452
patients required	451
iu ml	451
different types	451
ii score	451
national institute	449
phase iii	449
severe illness	448
days post	447
ejection fraction	447
angiotensin ii	446
dimer levels	445
cell lung	445
gvhd prophylaxis	445
york city	444
cerebrospinal fluid	444
patient management	443
adverse reactions	443
two years	443
ards patients	443
skeletal muscle	443
study clinical	442
cardiovascular risk	440
glass opacities	440
human immunodeficiency	440
ill covid	439
healthcare providers	439
immunodeficiency virus	439
acute rejection	438
leading cause	438
response rate	436
underlying disease	436
results show	435
respiratory system	434
drug administration	434
group i	434
one hundred	433
disease patients	433
red cells	433
healthy subjects	433
graft failure	432
medical treatment	432
review board	431
status epilepticus	428
institutional review	428
well known	427
term follow	426
adipose tissue	426
fl uid	426
pandemic influenza	426
proinflammatory cytokines	426
less likely	426
viral shedding	425
commercially available	424
interstitial pneumonia	424
related complications	424
cell lymphoma	423
th day	422
radiation therapy	422
mean arterial	422
months post	421
copd patients	421
cardiogenic shock	421
elevated levels	420
male patients	419
demographic data	419
adult inpatients	418
noninvasive ventilation	418
acute liver	417
cytokine production	416
spike protein	416
laboratory data	413
hospitalized covid	413
quality control	412
retrospectively reviewed	411
positive correlation	411
severe ards	411
clinical diagnosis	409
cell disease	409
blood count	408
care facilities	407
blood vessels	405
renal transplant	405
serum samples	404
aft er	404
scoring system	404
thrombotic complications	404
close contact	404
disease course	404
nosocomial infection	403
general anesthesia	403
connective tissue	403
days later	402
also observed	402
mouse model	402
survival rates	401
selected patients	401
written informed	400
ace expression	400
gastric cancer	400
patients using	399
ten patients	399
linear regression	399
myeloid leukemia	398
natural history	398
adverse event	398
severe asthma	398
diagnostic tests	398
antiviral treatment	397
currently available	397
prognostic value	397
resistant staphylococcus	397
en el	397
allogeneic hsct	396
chronic diseases	396
primary endpoint	396
working group	395
collected data	395
elective surgery	395
pulmonary vascular	395
median duration	395
three cases	394
data collected	394
blood culture	394
creative commons	394
neurocritical care	393
congestive heart	393
critical patients	393
drug interactions	393
first year	393
cell counts	392
risk assessment	392
adverse outcomes	392
first hours	392
cardiovascular diseases	391
three times	391
medical record	391
case fatality	390
remains unclear	390
mortality among	390
may reduce	390
high rate	390
newly diagnosed	390
squamous cell	389
acute coronary	389
gas exchange	389
cell types	389
chest radiography	389
term outcomes	388
dry cough	388
respiratory illness	388
patients reported	387
internal medicine	387
primary immunodeficiency	387
six months	386
early stages	386
one month	385
liver cirrhosis	385
nephrotic syndrome	385
may present	385
healthy individuals	384
viral clearance	384
grade ii	384
unrelated donor	383
symptomatic patients	383
immunosuppressive therapy	383
health services	383
infectious agents	383
acute myeloid	382
significant association	382
prone position	382
amino acids	381
small sample	381
flow nasal	381
innate immunity	380
female patients	380
poor outcomes	380
phase i	380
control subjects	380
corticosteroid therapy	380
study conducted	379
one week	379
acute ischemic	379
patient received	378
intracranial pressure	378
identify patients	377
main outcome	377
first step	377
surgical mask	376
hearing loss	376
results finding	376
covid patients	375
risk stratification	375
health status	375
suspected covid	375
neurological symptoms	374
transfusion medicine	373
remaining patients	373
determined using	373
copies ml	373
american society	373
european society	373
defi ned	372
time period	372
nasopharyngeal swab	372
preliminary data	371
alveolar damage	371
individual patient	371
patient died	371
ventilatory support	370
patients affected	370
blood stem	370
age range	369
broad spectrum	369
corona virus	369
arterial hypertension	368
liver transplant	368
icu mortality	367
platelet counts	367
increased levels	366
young adults	366
organ damage	365
potential risk	365
grade iii	365
serious adverse	365
study protocol	365
key role	364
will help	363
blood volume	363
compared using	362
class ii	362
antimicrobial resistance	362
prothrombin time	361
graft versus	361
lung biopsy	361
study shows	360
low levels	360
data regarding	360
cell responses	360
ground glass	360
clinical significance	359
human coronavirus	359
studies suggest	359
chronic disease	359
showed significant	359
airway management	358
antiviral drugs	358
least two	358
also showed	358
bariatric surgery	358
may affect	357
mycophenolate mofetil	357
cd cell	357
abstract background	357
ct imaging	357
small cell	357
adaptive immune	357
emergency medicine	356
idiopathic pulmonary	356
inflammatory mediators	356
interim guidance	356
patients whose	354
may improve	354
much higher	354
endotracheal tube	354
mg twice	354
studies showed	353
medical conditions	353
expression levels	353
acute exacerbation	353
chest radiographs	353
higher rate	352
also reported	351
mortality risk	351
respiratory viral	351
cerebrovascular disease	350
care system	350
patient presented	350
coronavirus infections	349
negative predictive	349
high frequency	349
acute lymphoblastic	349
chronic renal	349
neutropenic patients	348
stage renal	348
antibiotic resistance	348
major cause	348
laparoscopic surgery	347
emergency departments	347
antiviral activity	347
otitis media	347
group ii	346
months later	346
immune deficiency	345
birth weight	345
control groups	345
significantly improved	345
may represent	344
health systems	344
bile duct	343
neurological manifestations	343
kidney transplantation	343
peritoneal dialysis	343
cancer treatment	343
lg ml	343
also known	343
plasminogen activator	343
hematologic malignancies	343
clinical study	342
healthy donors	341
evidence suggests	341
many cases	341
treatment strategies	341
health commission	341
three different	341
respiratory virus	341
springer nature	341
antimicrobial agents	340
care patients	340
lung diseases	340
healthcare systems	339
reverse transcription	339
jurisdictional claims	338
negative patients	338
institutional affiliations	338
imaging features	338
blood donor	338
quality improvement	338
published maps	338
remains neutral	337
nature remains	337
infl uenza	337
care settings	336
stimulating factor	336
available data	336
cell culture	336
less common	336
corticosteroid treatment	336
three days	336
parenteral nutrition	335
higher rates	335
mean duration	335
first line	335
including patients	335
line treatment	335
radiation dose	334
potential therapeutic	334
operative time	334
evaluated using	334
secondary outcomes	334
cell function	333
room air	333
may include	333
vascular endothelial	333
lung transplant	333
adhesion molecules	333
randomized trials	333
carbon dioxide	333
year survival	333
clinical status	332
nursing staff	332
cell therapy	332
versus host	332
deep vein	332
respiratory diseases	332
treatment option	332
clinical examination	332
pcr testing	332
drug therapy	331
kg min	331
clinical research	331
younger patients	331
clinical response	330
herpes simplex	330
mg daily	330
clinical decision	330
teaching hospital	330
mass spectrometry	330
patient satisfaction	330
acute pulmonary	330
specific ige	329
virus infections	329
prospective studies	329
will require	329
controlled study	329
global pandemic	329
protective effect	329
will provide	328
patient age	328
patient groups	328
vast majority	328
fatty acids	327
health professionals	327
hematopoietic cell	326
blood supply	326
limited data	326
neurological complications	325
chronic pain	325
partial pressure	325
hubei province	325
pathological findings	325
colon cancer	325
per minute	325
square test	325
propensity score	325
infection may	324
statistical analyses	324
cardiovascular system	324
thoracic surgery	324
observational cohort	323
expiratory pressure	323
infected individuals	323
data indicate	323
antibiotic use	323
may develop	323
early phase	323
study aims	323
cancer care	322
clinical setting	322
single dose	322
rectal cancer	322
growth factors	322
tyrosine kinase	321
retrospective observational	321
sars cov	321
surgical procedure	321
protein levels	321
global health	320
year follow	320
molecular mechanisms	320
macrophage activation	319
supplementary material	319
potential role	319
nutritional status	319
may need	319
skin lesions	319
patients also	319
fio ratio	319
receptor antagonist	318
hazard ratio	318
retrospective chart	318
calculated using	318
thoracic society	318
host cells	318
systolic blood	318
center study	318
consensus statement	318
clinical evidence	318
airway epithelial	317
renal impairment	317
chronic inflammatory	316
pacientes con	316
life support	316
kawasaki disease	316
autologous stem	315
hepatic encephalopathy	315
children aged	315
patient data	315
regression models	315
higher prevalence	315
generation sequencing	315
pulmonary arterial	315
high sensitivity	315
clinical care	315
transcription factor	314
functional outcome	314
thrombotic events	314
tissue damage	314
fl ow	314
significant changes	314
well established	313
brain tissue	313
community acquired	313
severe coronavirus	313
patient group	313
also associated	312
mean time	312
postoperative day	312
common symptoms	311
underlying diseases	311
positive pressure	311
term outcome	310
chronic lung	309
clinical use	309
diseases society	309
significant risk	309
wild type	309
care services	309
therapeutic strategies	309
inflammatory responses	309
complement activation	309
laboratory parameters	308
preventive measures	308
group compared	308
influenza infection	308
angiotensin converting	308
direct contact	308
exome sequencing	308
avian influenza	307
cohort studies	307
acute exacerbations	307
autoimmune disease	307
competing interests	307
routine use	306
intervention group	306
high doses	306
cmv reactivation	306
lymphoblastic leukemia	306
recently published	306
years ago	305
metabolic acidosis	305
hodgkin lymphoma	305
chronic respiratory	305
high resolution	305
troponin i	304
organ transplant	304
patient underwent	304
cause mortality	304
requiring mechanical	303
standard treatment	303
discharged home	303
retrospective case	303
health emergency	303
glasgow coma	303
cell cycle	302
clinical information	302
ct images	302
within months	302
tracheal intubation	302
whole body	301
negative results	301
control patients	301
coronary heart	301
wound healing	300
affected patients	300
developing countries	300
beneficial effects	300
bloodstream infections	299
pcr test	299
animal model	299
postoperative period	298
mycoplasma pneumoniae	298
clinical suspicion	298
previous study	298
care setting	297
barr virus	297
without permission	297
atopic dermatitis	297
pleural effusions	297
marrow transplant	297
analysed using	297
pressure ventilation	297
specific antibodies	296
study will	296
receptor blockers	296
total body	296
thromboembolic events	296
factor viii	296
induced lung	295
positive end	295
organ transplantation	295
risk group	295
fold increase	295
cox regression	294
cell receptor	294
placebo group	294
portal vein	294
multidisciplinary team	294
lung ultrasound	294
chest wall	293
reported cases	293
better understanding	293
relative risk	293
kidney function	293
emergency surgery	293
intensity conditioning	293
therapy may	293
general surgery	292
mild symptoms	292
renal dysfunction	292
hospitalised patients	292
ct angiography	292
pain management	292
acute leukemia	292
cmv infection	291
immune reconstitution	291
positive predictive	291
allowed without	291
reuse allowed	291
reactive oxygen	291
hepatic failure	291
medical university	290
therapeutic options	290
positive airway	290
platelet concentrates	290
care professionals	290
confidence intervals	289
severe cap	289
fungal infection	289
first months	289
safety profile	289
every patient	289
autosomal recessive	289
independent predictor	289
radiation exposure	289
oxygen delivery	289
successfully treated	288
host immune	288
systematic reviews	288
hematological malignancies	288
first week	288
plasma therapy	288
hemophagocytic lymphohistiocytosis	287
note springer	287
positive cells	287
time point	287
reduced intensity	287
cardiopulmonary bypass	286
one third	286
negative bacteria	286
myeloablative conditioning	286
inflammatory cells	286
hcv rna	286
table shows	286
mast cells	285
severe symptoms	285
disease caused	285
pulmonary infection	285
adverse drug	284
patients experienced	284
beneficial effect	284
multivariate logistic	284
brain death	283
whenever possible	283
similar results	283
surgical resection	283
severe infection	282
plasma samples	282
intubated patients	282
hemolytic anemia	282
female patient	282
qt interval	282
increased significantly	282
complete blood	282
muscle mass	282
medical students	282
immune function	282
transfusion reactions	282
times higher	281
data show	281
small intestine	281
outcomes among	281
severity score	280
saudi arabia	280
ace receptor	280
male patient	280
flow rate	279
ulcerative colitis	279
diagnostic testing	279
median number	279
enrolled patients	279
cerebral edema	279
hospital admissions	278
deceased patients	278
aspiration pneumonia	278
multiorgan failure	278
cancer cell	278
opportunistic infections	278
carotid artery	278
frozen plasma	277
two days	277
radiological findings	277
past years	277
frequently used	277
standard care	277
blood mononuclear	277
renal transplantation	277
receiver operating	277
taken together	276
laboratory testing	276
human metapneumovirus	276
serum ferritin	276
imaging studies	276
solid tumors	276
fresh frozen	276
intracerebral hemorrhage	276
advanced age	276
low molecular	276
crp levels	276
crucial role	275
success rate	275
lower risk	275
acute pancreatitis	275
treatment failure	275
clinical picture	275
abdominal wall	275
study reported	275
weight heparin	274
may explain	274
south korea	274
missing data	274
graft survival	274
intravenous drip	274
umbilical cord	274
independent predictors	273
strongly associated	273
clinical evaluation	273
least days	273
relatively low	273
examination revealed	273
worse outcomes	273
social media	273
severe hepatitis	272
glomerular filtration	272
better understand	272
altered mental	272
immune cell	272
past medical	272
clinical experience	272
clinical benefit	272
rank test	272
prognostic factor	272
liver biopsy	272
invasive aspergillosis	272
matched unrelated	271
data will	271
short term	271
plasma cells	271
pulmonary complications	271
lower extremity	271
term survival	271
antibody responses	271
hospital length	271
coagulation parameters	271
clostridium difficile	271
pulmonary infiltrates	271
results obtained	271
correlation coefficient	271
nuclear medicine	270
room temperature	270
older people	270
false positive	270
common cold	270
line therapy	269
high rates	269
improve patient	269
greater risk	269
airway obstruction	269
failure assessment	268
hospital death	268
retrospectively analyzed	268
new zealand	268
imaging modalities	268
intracranial hemorrhage	268
laparoscopic approach	267
study using	267
descriptive statistics	267
increased incidence	267
european countries	267
asthma control	267
may become	267
immune dysregulation	267
results demonstrate	267
hemodynamic instability	267
oxygen species	267
risk score	266
electronic health	266
portal hypertension	266
serum albumin	266
chinese center	265
renal insufficiency	265
mortality due	265
pediatric population	264
neutrophil count	264
within weeks	264
first day	264
increased expression	264
current evidence	264
severe forms	264
angiotensin system	264
higher proportion	264
pulse oximetry	264
performance status	264
current pandemic	263
blood tests	263
trend towards	263
saps ii	263
closely related	262
complete response	262
patients present	262
gastric bypass	262
elevated serum	262
inflammatory diseases	262
vascular disease	262
considered statistically	261
face mask	261
stroke patients	261
severe infections	261
clinical condition	261
invasive fungal	260
lessons learned	260
progressive disease	260
international guidelines	260
please specify	260
th cells	260
drug resistance	260
among children	260
information regarding	260
outpatient clinic	259
th percentile	259
million people	259
many countries	259
clinical deterioration	259
tidal volumes	259
inflammatory cytokine	259
urine output	259
upper airway	259
functional status	259
significantly elevated	259
vena cava	259
confl ict	259
old girl	259
early treatment	258
randomized study	258
relatively high	258
study found	258
plasma exchange	258
treatment groups	258
care team	258
time spent	258
severe complications	258
severe sars	258
ill patient	258
steroid therapy	257
fi brosis	257
old boy	257
admitted patients	257
successful treatment	257
also performed	257
diagnostic tool	257
complication rate	257
every hours	257
icu discharge	256
glucose levels	256
previous reports	256
chronic inflammation	256
clinical parameters	256
hbv infection	256
days prior	256
study also	256
published data	255
high grade	255
acute graft	255
plasma concentrations	255
acute stroke	255
antiretroviral therapy	255
physical exam	255
like symptoms	255
extracellular matrix	255
combined immunodeficiency	255
signal intensity	254
en pacientes	254
investigate whether	254
team members	254
uric acid	254
clinical efficacy	254
accepted article	254
ace inhibitors	254
organizing pneumonia	254
abstract type	254
clinical relevance	253
clinical impact	253
host cell	253
reverse transcriptase	253
often associated	253
peripheral neuropathy	253
may benefit	253
pediatric intensive	253
will continue	253
inflammatory drugs	253
may reflect	253
less severe	253
north america	252
vascular resistance	252
individual patients	252
cd expression	252
clinical presentations	252
cardiac function	251
dependent manner	251
respiratory pathogens	251
enteral nutrition	251
host response	250
within normal	250
platelet aggregation	250
three years	250
surgery patients	250
among covid	250
roc curve	250
foreign body	250
gene therapy	250
clinical isolates	250
glycemic control	250
viral loads	250
significantly correlated	250
protease inhibitor	249
generating procedures	249
bacterial pathogens	249
blood product	249
activated charcoal	249
epithelial cell	249
clinical conditions	249
also present	249
heart association	249
coronavirus pandemic	249
included studies	249
analysis using	249
neutralizing antibodies	249
thrombotic microangiopathy	249
spontaneous breathing	249
liver enzymes	249
cox proportional	248
blood collection	248
nursing home	248
gestational age	248
pcr assay	248
klebsiella pneumoniae	248
treat patients	248
airway inflammation	248
term care	248
confi rmed	247
health insurance	247
based study	247
inspired oxygen	247
will allow	247
pulmonary rehabilitation	247
creatinine clearance	247
fluid resuscitation	246
early identification	246
fluid balance	246
icu care	246
unrelated donors	246
group received	246
month follow	246
income countries	246
brain mri	246
imaging techniques	245
increasing number	245
study suggests	245
also used	245
increased susceptibility	245
cardiovascular events	244
several days	244
recombinant human	244
laboratory results	244
urgent need	244
following criteria	244
infections caused	244
useful tool	244
trauma center	243
also significantly	243
lymphocyte subsets	243
disease status	243
infected cells	243
lung parenchyma	243
prospectively collected	243
among hospitalized	243
improved survival	243
host defense	242
important factor	242
four cases	242
sleep apnea	242
hypertonic saline	242
clinical assessment	242
seasonal influenza	242
financial support	242
coagulation factors	242
conditioning regimens	241
coma scale	241
studies reported	241
therapeutic option	241
demographic characteristics	241
false negative	241
venous catheter	241
cardiac involvement	241
several limitations	241
cardiac disease	241
biopsy specimens	241
filtration rate	241
contact tracing	241
gastrointestinal bleeding	240
prospective randomized	240
submitted work	240
natriuretic peptide	240
medical therapy	240
lower mortality	240
per week	240
donor chimerism	240
icu length	240
critical role	240
resistant bacteria	240
risk groups	240
viral hepatitis	240
ethics regulations	239
right heart	239
young patients	239
diagnostic value	239
compassionate use	239
cerebral blood	239
surgical management	239
next generation	239
disease process	239
high flow	239
initial treatment	239
drug reactions	238
activation syndrome	238
metastatic disease	238
poorly understood	238
fold higher	238
side effect	238
healthcare facilities	238
extremely rare	238
body fluids	238
failure due	238
medical management	237
cardiovascular complications	237
high quality	237
hypercoagulable state	237
respiratory function	237
among others	237
antiphospholipid antibodies	236
spectrum antibiotics	236
lung damage	236
cfu ml	236
influenza viruses	236
seven days	235
first report	235
los pacientes	235
study demonstrated	235
health outcomes	235
first study	235
health service	235
acute cardiac	235
coronary syndrome	235
comorbid conditions	235
diffi cult	235
mean follow	235
respiratory secretions	234
university medical	234
signaling pathway	234
genetic testing	234
chronic rhinosinusitis	234
alanine aminotransferase	234
cell entry	234
national institutes	233
cell subsets	233
creatine kinase	233
significant impact	233
therapeutic approach	233
blood transfusions	233
differ significantly	233
lymphocyte counts	233
bladder cancer	232
less frequently	232
transplanted patients	232
chronic bronchitis	232
randomly assigned	232
significantly greater	232
care delivery	232
platelet activation	232
med doi	232
adhesion molecule	232
comparative study	232
renal biopsy	232
contrast enhancement	231
major role	231
treated group	231
germ cell	231
blood banks	231
platelet transfusion	231
graft function	231
patient demographics	231
rna polymerase	231
mean value	231
neck cancer	231
previously healthy	230
sequential organ	230
predictive factors	230
stromal cells	230
current covid	230
groups according	230
pneumonia caused	230
significantly less	230
requiring hospitalization	230
mycobacterium tuberculosis	230
improve outcomes	230
life threatening	230
american heart	230
important lessons	230
early recognition	230
paediatric patients	230
surgical masks	230
healthcare personnel	230
hypoxemic respiratory	230
artery bypass	229
open access	229
antibody response	229
five years	229
appropriate treatment	229
blood sample	229
viral entry	229
initial presentation	229
disease onset	229
transmission dynamics	229
infection rates	228
oral cavity	228
pressure support	228
many studies	228
moderate covid	228
relapse mortality	228
patients often	228
will likely	228
response syndrome	228
grade i	228
preliminary report	228
assess whether	228
injured patients	227
cirrhotic patients	227
patient populations	227
autosomal dominant	227
common causes	226
laboratory values	226
new onset	226
readily available	226
eligible patients	226
mild disease	226
positive cases	226
mean difference	226
patients enrolled	226
patient survival	226
cancer surgery	225
five cases	225
data obtained	225
immune checkpoint	225
incidence rate	225
pulmonary involvement	225
kg iv	225
medical patients	225
thromboembolic complications	225
days following	225
positively correlated	225
lower levels	225
critical covid	224
imaging modality	224
surface area	224
cardiac troponin	224
limited number	224
active disease	224
differentially expressed	224
target cells	224
invasive procedures	224
mainly due	224
time course	224
positive blood	224
several factors	224
recurrent infections	223
se recomienda	223
leydig cells	223
operating characteristic	223
cd ra	223
progenitor cells	223
adult respiratory	223
reperfusion injury	223
significant morbidity	223
guidelines recommend	222
coronavirus outbreak	222
hernia repair	222
case study	222
cell depletion	222
massive transfusion	222
one patients	222
transfusion service	222
staff members	222
pneumonia patients	222
patients within	221
hospital setting	221
rheumatic diseases	221
cytokine levels	221
available evidence	221
chest tube	221
treatment response	221
eye protection	221
statistical difference	221
resistant strains	221
susceptibility testing	221
plasma membrane	221
controlled clinical	221
secondary bacterial	220
severe clinical	220
treatment may	220
considered significant	220
disease may	220
different clinical	220
receptor binding	220
central role	220
center experience	220
daily living	220
venous blood	220
previously published	220
patients referred	220
two months	219
continuous infusion	219
like receptor	219
angiotensin receptor	219
face shield	219
first reported	219
lung involvement	219
worse prognosis	219
head injury	219
healthcare settings	219
specific cd	219
day post	219
shock patients	218
antiviral agents	218
infection risk	218
glucose tolerance	218
expert consensus	218
weight gain	218
surviving sepsis	218
healthy control	218
hydrogen peroxide	218
first two	218
partial thromboplastin	218
coronary angiography	218
signaling pathways	217
western blotting	217
conservative treatment	217
flow oxygen	217
viral particles	217
tissue factor	217
interventional radiology	217
consecutive days	217
liver damage	217
two independent	217
cardiac index	217
cell adhesion	217
patient selection	216
clinical settings	216
using standard	216
low level	216
injury severity	216
high fever	216
targeted therapy	216
studied patients	216
positive result	216
lymphocyte ratio	215
identified patients	215
clinical history	215
renal cell	215
artificial intelligence	215
ischemic heart	215
additional information	215
sedimentation rate	215
therapeutic hypothermia	215
large cohort	214
lavage fluid	214
liver dysfunction	214
blood gases	214
probably due	214
mhc class	214
systemic sclerosis	213
wide variety	213
cardiopulmonary resuscitation	213
healthy children	213
hemorrhagic shock	213
diagnostic test	213
thromboplastin time	213
associated infections	213
fatty acid	213
radiographic findings	213
two studies	213
immunosuppressed patients	213
syndrome associated	213
blood donations	213
nursing homes	213
bronchiolitis obliterans	213
antiphospholipid syndrome	213
person transmission	212
quality assurance	212
ncov infection	212
likely due	212
abdominal surgery	212
obstructive sleep	212
human coronaviruses	212
american thoracic	212
care hospital	212
fatty liver	212
suspected cases	212
life expectancy	212
food allergy	212
second group	212
dose reduction	212
inflammatory process	211
higher level	211
simplex virus	211
alveolar macrophages	211
health problem	211
lower limb	211
thrombocytopenic purpura	211
routine clinical	211
mcg kg	211
ill adults	211
cancer center	211
using spss	211
residual disease	211
infection rate	211
allergic reactions	211
fdg pet	210
time reverse	210
may indicate	210
dose chemotherapy	210
five days	210
mean number	210
management strategies	210
good outcome	210
accurate diagnosis	210
liver fibrosis	210
specific treatment	210
neurologic manifestations	209
ace receptors	209
patients years	209
febrile neutropenia	209
data set	209
many years	209
igg antibodies	209
igg levels	209
also important	209
muscle cells	209
hiv patients	209
related quality	209
data available	208
severe combined	208
patienten mit	208
cells may	208
health authorities	208
may serve	208
loading dose	208
care facility	208
cell source	208
median survival	208
significantly better	208
viral respiratory	208
significant proportion	208
activated protein	207
gel electrophoresis	207
first group	207
serum concentrations	207
neutrophil extracellular	207
surgical site	207
cell membrane	206
vitro studies	206
liver diseases	206
situ hybridization	206
spontaneous pneumothorax	206
transplant recipient	206
average time	206
common clinical	206
chronic lymphocytic	206
influenza pneumonia	206
none declared	206
sepsis campaign	206
one day	206
therapeutic anticoagulation	206
brain barrier	205
study demonstrates	205
randomly selected	205
sputum samples	205
cerebral artery	205
high morbidity	205
asthmatic patients	205
promising results	205
unclear whether	205
contrast agent	205
influenza vaccination	205
adverse effect	205
haematopoietic stem	205
pulmonary tuberculosis	204
bacterial contamination	204
time rt	204
protein kinase	204
studies will	204
antibody titers	204
significant effect	204
induction therapy	204
chest computed	204
every day	204
oral administration	203
new cases	203
abnormal coagulation	203
tumor size	203
smoking cessation	203
sleeve gastrectomy	203
develop severe	203
protease inhibitors	203
bal fluid	203
might also	203
final diagnosis	203
cases per	203
blood units	203
also occur	203
low grade	203
hcv infection	203
serious complications	203
tertiary hospital	202
close monitoring	202
first patient	202
patients due	202
cancer therapy	202
respiratory specimens	202
respiratory droplets	202
confirmed sars	202
emergency use	202
hsct recipients	202
bloodstream infection	202
clinical severity	202
intracranial hypertension	202
stable patients	202
odds ratios	201
negative impact	201
partial response	201
year os	201
remains controversial	201
patient showed	201
last decade	201
post transplant	201
developed acute	200
highest risk	200
oral health	200
must also	200
recent data	200
treatment protocol	200
adults hospitalized	200
within one	200
done using	200
outcome measure	200
high number	200
cardiac dysfunction	200
march th	200
nucleic acids	200
peripheral nerve	200
medical school	200
normal saline	200
within minutes	200
needle aspiration	199
often used	199
aspartate aminotransferase	199
short period	199
tissue samples	199
glass opacity	199
therapeutic approaches	199
acute appendicitis	199
may vary	199
health problems	199
continuous positive	199
acute physiology	199
clinical manifestation	199
postoperative pain	199
may influence	199
decreased significantly	198
higher among	198
protective measures	198
lower lobe	198
back pain	198
severe form	198
health workers	198
presenting symptoms	198
primary pulmonary	198
ovarian cancer	198
cell response	198
two types	197
current guidelines	197
patients must	197
stage iii	197
mean values	197
important cause	197
maintenance therapy	197
con covid	197
commonly seen	197
emergency medical	197
main cause	197
sample collection	197
hiv aids	197
practice guideline	197
narrative review	197
last months	197
physical therapy	197
urine samples	197
four groups	197
therapeutic strategy	197
gi tract	196
binding protein	196
type iii	196
patient outcome	196
signal transduction	196
induced thrombocytopenia	196
drug use	196
acute bronchitis	196
gut microbiota	196
future research	196
effi cacy	196
therapeutic target	196
new therapeutic	196
patients taking	196
nosocomial pneumonia	196
investigated whether	196
enteral feeding	195
alkaline phosphatase	195
observation period	195
treatment guidelines	195
negative correlation	195
related adverse	195
cells expressing	195
neuromuscular blockade	195
mcg ml	195
epidemiological characteristics	194
usual care	194
retrospective studies	194
patient may	194
outcome data	194
highly sensitive	194
treating patients	194
genomic dna	194
test result	194
operation time	194
data sets	194
tested negative	194
special attention	194
severe community	194
haemophilus influenzae	194
giant cell	194
pulmonary aspergillosis	193
spatial resolution	193
data showed	193
reduce mortality	193
severe influenza	193
therapeutic interventions	193
introduction background	193
throat swab	193
upper limit	193
face masks	193
iron deficiency	193
median length	193
muscle strength	193
one hour	193
supine position	193
human transmission	193
least months	193
cell viability	192
cd count	192
death rate	192
good clinical	192
ill icu	192
epidemiological data	192
relatively small	192
bowel obstruction	192
erythrocyte sedimentation	192
standard therapy	192
without evidence	191
clinical criteria	191
subgroup analysis	191
nationwide analysis	191
findings may	191
remained stable	191
without significant	191
well documented	191
short time	191
ventricular dysfunction	191
high degree	191
treatment modalities	191
stage i	190
wide spectrum	190
required mechanical	190
less frequent	190
multivariable logistic	190
adaptive immunity	190
urea nitrogen	190
large vessel	190
tissue injury	190
survival benefit	190
results may	190
gram negative	190
factor receptor	190
nutritional support	190
multivariable analysis	190
patients transplanted	190
died due	189
failure requiring	189
studies using	189
last follow	189
male sex	189
patients following	189
per cent	189
american academy	189
inflammatory disease	189
phase trial	189
major risk	189
nerve conduction	189
group patients	189
chest imaging	189
showed significantly	189
kg body	189
extracellular traps	188
treatment strategy	188
will discuss	188
thromboembolic disease	188
studies show	188
transcription factors	188
lactate levels	188
adjuvant chemotherapy	188
end stage	188
venous catheters	188
muscle weakness	188
limited resources	188
environmental factors	188
previously shown	188
right ventricle	188
binding domain	188
venous pressure	188
particularly important	188
significant change	188
complications associated	188
head ct	188
laparoscopic cholecystectomy	188
hospital day	187
clinical specimens	187
significant number	187
negative bacilli	187
mechanisms underlying	187
using two	187
examination showed	187
recently reported	187
treat covid	187
procedure details	187
common complication	187
response rates	187
literature search	187
transforming growth	187
patients develop	187
hospital cardiac	187
arterial oxygen	187
hand washing	187
fatal outcome	187
ms patients	187
skin prick	186
factors may	186
specific antibody	186
developed severe	186
ischaemic stroke	186
study including	186
northern italy	186
blood center	186
younger age	186
disease transmission	186
oncology patients	185
left ventricle	185
ventricular function	185
sertoli cells	185
therapeutic intervention	185
anticoagulant therapy	185
severe pulmonary	185
highly contagious	185
family member	185
asthma exacerbations	185
icu beds	185
ferritin levels	185
diagnostic yield	184
suspected patients	184
enzyme inhibitors	184
illness severity	184
best practices	184
cell populations	184
pneumococcal pneumonia	184
coronavirus sars	184
operating rooms	184
decreased mortality	184
african american	184
emergency physicians	184
therapeutic effect	183
atypical pneumonia	183
classified according	183
locally advanced	183
expression level	183
deep venous	183
skull base	183
expert opinion	183
information system	183
acinetobacter baumannii	183
stroke volume	183
nasopharyngeal swabs	183
eleven patients	183
took place	183
following treatment	183
infection among	183
qt prolongation	183
normal values	183
group showed	183
haematological malignancies	183
best practice	183
cases showed	183
take place	183
normal controls	182
endoplasmic reticulum	182
mm patients	182
lung volume	182
secondary infection	182
aldosterone system	182
study provides	182
medical personnel	182
treatment regimens	182
several clinical	182
daily dose	182
continuous renal	182
cells showed	181
blood component	181
possible role	181
mast cell	181
immune complexes	181
antifungal therapy	181
many different	181
multiplex pcr	180
head trauma	180
higher doses	180
parainfluenza virus	180
standard precautions	180
also included	180
medical education	180
significant role	180
ibd patients	180
long time	180
middle ear	180
one hand	180
invasive surgery	180
deficient mice	180
supplementary table	180
proportional hazards	180
published studies	180
hours post	179
single centre	179
academic medical	179
animal studies	179
widespread use	179
organ systems	179
coronary arteries	179
experimental studies	179
activated partial	179
different levels	179
neutralizing antibody	179
clinic visits	179
mri findings	179
traditional chinese	178
lower extremities	178