bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
intensive care	1644
septic shock	958
mechanical ventilation	894
care unit	850
critically ill	846
ill patients	659
patients admitted	576
mortality rate	536
risk factors	518
critical care	514
mean age	464
hospital mortality	458
icu admission	414
two groups	404
cardiac arrest	396
apache ii	387
control group	366
icu stay	356
icu patients	348
acute respiratory	330
respiratory failure	325
mortality rates	320
trauma patients	313
organ failure	310
blood pressure	300
severe sepsis	290
significantly higher	286
ml kg	284
emergency department	279
retrospective study	269
sofa score	260
university hospital	256
mechanically ventilated	256
mg kg	256
respiratory distress	250
observational study	249
cardiac surgery	246
day mortality	242
statistically significant	240
ethics regulations	238
significant difference	228
septic patients	227
cohort study	227
ii score	222
brain injury	220
hospital stay	218
logistic regression	215
care units	214
adult patients	213
study period	212
years old	206
lung injury	205
ng ml	203
renal failure	202
multivariate analysis	196
cardiac output	194
distress syndrome	192
arterial pressure	189
one patient	189
tidal volume	188
significant differences	187
pao fio	183
icu mortality	182
prospective study	182
patients received	181
patients undergoing	180
median age	177
two patients	177
included patients	173
heart rate	171
renal replacement	167
organ dysfunction	166
ventilated patients	166
central venous	164
patients treated	162
replacement therapy	159
traumatic brain	159
statistical analysis	158
kidney injury	157
blood flow	157
saps ii	156
factors associated	155
high mortality	150
arterial blood	149
significantly lower	147
present study	147
acute kidney	144
consecutive patients	143
patients without	140
mean arterial	140
high risk	139
pg ml	138
regression analysis	138
ct scan	136
multiple organ	136
risk factor	135
signifi cant	135
primary outcome	135
higher mortality	133
blood samples	133
antibiotic therapy	133
mg dl	132
signifi cantly	130
critical illness	128
cardiac index	128
among patients	126
within hours	123
prospective observational	122
severity score	122
patients died	121
ards patients	118
heart failure	117
fi rst	117
performed using	117
hospital discharge	117
patients receiving	116
pulmonary artery	115
month period	113
increased mortality	113
shock patients	112
least one	112
inclusion criteria	112
elderly patients	111
body weight	110
independently associated	110
three patients	110
respiratory rate	109
blood gas	109
first hours	108
injury severity	108
icu discharge	108
predictive value	108
year period	107
ml min	105
average age	105
increased risk	105
acute lung	103
retrospective cohort	103
excess mortality	102
univariate analysis	102
overall mortality	101
mortality risk	101
airway pressure	100
cardiogenic shock	100
lactate levels	99
poor outcome	99
abdominal pain	99
systematic review	99
acute renal	98
blood glucose	98
retrospective analysis	97
fl uid	96
blood loss	96
inflammatory response	96
pressure support	95
prognostic factors	95
adverse events	95
myocardial infarction	94
glasgow coma	94
four patients	93
kg min	93
severe ards	92
oxygen saturation	92
associated pneumonia	92
trauma center	92
invasive ventilation	92
surgical patients	91
significant increase	91
head injury	90
patients hospitalized	90
influenza pandemic	90
demographic data	90
surgical treatment	90
reactive protein	90
icu length	89
spontaneous breathing	89
group i	89
public health	89
first days	89
significantly associated	88
patients underwent	88
long term	88
clinical findings	87
odds ratio	87
clinical outcomes	87
confidence interval	86
patients requiring	86
age years	85
gas exchange	84
within days	83
th day	81
randomized controlled	81
clinical practice	81
five patients	81
informed consent	81
clinical characteristics	80
collected data	80
fio ratio	80
emergency surgery	80
hospitalized patients	80
coronary artery	80
mm hg	79
study included	79
postoperative period	78
mortality among	78
health care	78
severe acute	78
membrane oxygenation	77
blood gases	77
measured using	77
patients included	76
prospective cohort	76
diff erence	76
hospital cardiac	76
surgical icu	75
extracorporeal membrane	75
left ventricular	75
care medicine	75
pulmonary embolism	75
independent risk	74
six patients	74
computed tomography	73
plasma levels	73
united states	73
medical icu	72
neurological outcome	72
exclusion criteria	72
endotracheal tube	72
blood transfusion	72
analysis showed	72
survival rate	71
significantly increased	71
roc curve	70
red blood	70
nosocomial infections	70
renal function	69
regression model	69
hospital length	69
receiver operating	68
respiratory system	68
heart disease	68
per patient	68
cause mortality	68
pulmonary disease	68
case history	67
diabetes mellitus	67
stroke volume	67
statistical significance	66
linear regression	66
emergency room	66
invasive mechanical	66
seven patients	66
medical records	66
sex ratio	66
rib fractures	66
year old	66
interquartile range	65
patients aged	65
platelet count	65
ali ards	65
significantly different	65
hemodynamic parameters	65
diff erent	64
controlled trial	64
investigation results	64
severe head	64
coma scale	64
old male	64
oxygen delivery	64
results suggest	64
three groups	64
fluid responsiveness	64
eff ect	64
ischemic stroke	63
specific mortality	63
liver transplantation	63
adverse effects	62
conservative treatment	62
study aimed	62
acute appendicitis	62
blood cultures	62
mean duration	62
nitric oxide	62
fluid resuscitation	62
one case	62
copd patients	62
clinical trials	61
blunt trauma	61
infectious diseases	61
significant decrease	61
side effects	61
patients required	61
systolic blood	61
blood cell	61
significant correlation	60
functional outcome	60
commonly used	60
early diagnosis	60
median time	60
higher risk	59
previous studies	59
chronic obstructive	59
cardiopulmonary bypass	59
kidney disease	59
hospital admission	59
data collection	59
study conducted	59
prognostic value	59
pediatric intensive	59
fluid balance	59
atrial fibrillation	58
general surgery	58
acute phase	58
pulmonary edema	58
patients presented	58
serum creatinine	58
care patients	58
nine patients	57
acute pancreatitis	57
abdominal surgery	57
obstructive pulmonary	57
clinical trial	57
acquired pneumonia	57
study group	57
pseudomonas aeruginosa	57
whole blood	57
ventilatory support	57
small bowel	56
teaching hospital	56
surgical intervention	56
leading cause	56
data suggest	56
hemorrhagic shock	55
physical examination	55
data collected	55
epidemiological transition	55
severity scores	55
secondary outcomes	55
ejection fraction	54
head trauma	54
clinical data	54
cancer patients	54
intracranial hypertension	54
ethics committee	54
patients presenting	54
first day	54
international congresses	54
parenteral nutrition	53
abdominal trauma	53
age group	53
medical intensive	53
blood culture	53
right ventricular	53
prone positioning	53
clinical course	53
mean apache	52
eight patients	52
group ii	52
single center	52
scoring system	52
burn patients	52
standard deviation	52
one hundred	52
life support	52
cardiac function	52
artery bypass	52
pulmonary vascular	52
intracranial pressure	52
patients suffering	51
injured patients	51
case report	51
icu admissions	51
blood lactate	51
venous catheter	51
medical center	51
determine whether	51
vascular resistance	51
may lead	51
analyzed using	50
patient characteristics	50
major trauma	50
predictive factors	50
assessed using	50
acute physiology	50
randomly assigned	50
study showed	50
time points	50
success rate	50
eff ects	49
prone position	49
two cases	49
brain death	49
trauma care	49
total number	49
decision making	49
soft tissue	49
retrospective observational	49
common cause	49
patients developed	49
venous pressure	49
pilot study	49
blood volume	48
vital signs	48
enteral nutrition	48
acute care	48
defi ned	48
tertiary care	48
cardiovascular disease	48
sample size	48
surgical procedures	48
blood cells	48
tidal volumes	48
last years	48
urine output	48
multivariate logistic	47
hemodynamic instability	47
venous blood	47
chest wall	47
failure assessment	47
negative predictive	47
postoperative complications	47
operating characteristic	47
enteral feeding	47
one year	47
poor prognosis	47
prospectively collected	47
identifi ed	47
liver failure	47
respiratory tract	47
fl ow	47
inflammatory mediators	47
per day	46
mean values	46
significantly reduced	46
trauma registry	46
obese patients	46
continuous infusion	46
carbon dioxide	46
united kingdom	46
severe trauma	46
primary endpoint	46
study including	46
surgery patients	46
circulatory failure	46
staphylococcus aureus	46
year mortality	46
expiratory pressure	46
study shows	46
healthy volunteers	46
two different	46
lung cancer	46
blood products	46
general anesthesia	45
antibiotic treatment	45
baseline characteristics	45
medical treatment	45
diff erences	45
risk patients	45
coronavirus disease	45
severe tbi	44
patients showed	44
nosocomial infection	44
doc id	44
fluid administration	44
pulmonary hypertension	44
cord uid	44
respiratory mechanics	44
sofa scores	44
study aims	44
sequential organ	43
oxygen therapy	43
open reduction	43
body mass	43
organ donation	43
postoperative day	43
multiple trauma	43
study population	43
controlled trials	43
bacterial infection	42
clinically relevant	42
increased significantly	42
severe traumatic	42
support ventilation	42
clinical signs	42
internal fixation	42
medical care	42
abdominal wall	42
normal range	42
acute myocardial	42
patient outcomes	42
severely injured	42
correlation coefficient	42
surgical procedure	41
center study	41
systemic inflammation	41
compared using	41
general hospital	41
medical history	41
serum albumin	41
free days	41
identify patients	41
healthy subjects	41
general icu	41
may improve	41
independent predictor	41
oxygen consumption	41
higher incidence	41
lg ml	41
patients may	41
systemic inflammatory	40
hoc analysis	40
ten patients	40
cant diff	40
investigate whether	40
endothelial cells	40
emergency medicine	40
pandemic mortality	40
emergency medical	40
influenza mortality	39
widely used	39
related mortality	39
nursing staff	39
every hours	39
important role	39
airway management	39
infected patients	39
second group	39
patient died	39
mass index	39
studied patients	39
disease severity	39
descriptive study	39
therapeutic hypothermia	39
jugular vein	38
table shows	38
mean length	38
oxidative stress	38
infl ammatory	38
chronic kidney	38
considered significant	38
significant improvement	38
ii scores	38
high morbidity	38
clinical features	38
positive predictive	38
partial pressure	38
may also	38
extubation failure	38
mean time	38
per year	38
significantly decreased	38
patient care	38
cell count	38
exact test	38
internal medicine	37
tissue oxygenation	37
tertiary hospital	37
infectious complications	37
patient population	37
square test	37
aged years	37
time series	37
significant reduction	37
male patients	37
chest trauma	37
three days	37
glasgow outcome	37
sepsis patients	37
differ significantly	37
artery catheter	37
lactate level	37
chest pain	36
prolonged mechanical	36
mortality due	36
predict mortality	36
may help	36
pediatric patients	36
median length	36
serum levels	36
relative risk	36
hemodynamically stable	36
cardiopulmonary resuscitation	36
nervous system	36
patient safety	36
heart surgery	36
preliminary results	36
drotrecogin alfa	36
fluid challenge	36
acute brain	36
median duration	36
white blood	36
complication rate	36
groups according	35
one hour	35
nutritional support	35
older age	35
results indicate	35
old man	35
physiology score	35
acute exacerbation	35
hemodynamic monitoring	35
urinary tract	35
significant association	35
ct scans	35
patients using	35
major cause	35
including patients	35
massive transfusion	35
intubated patients	35
may result	35
clinical outcome	35
operating room	35
positive blood	35
case series	35
antimicrobial therapy	35
lower mortality	35
hip fracture	35
treated patients	35
mean value	35
requiring mechanical	35
metabolic acidosis	35
reduce mortality	34
large number	34
esophageal pressure	34
short term	34
ang ii	34
immune response	34
multicenter study	34
minimally invasive	34
coma score	34
damage control	34
subarachnoid hemorrhage	34
systolic function	34
lung volume	34
respiratory support	34
internal jugular	34
creatinine clearance	34
icu los	34
showed significant	34
cardiovascular diseases	34
emergency departments	34
group compared	34
pulmonary arterial	34
first group	34
supine position	33
endotracheal intubation	33
liver function	33
clinical examination	33
predicted mortality	33
incidence rate	33
medical staff	33
ventilator settings	33
average time	33
whitney test	33
assess whether	33
days mortality	33
analysed using	33
age groups	33
data analysis	33
compartment syndrome	33
acinetobacter baumannii	33
pleural effusion	33
high level	33
tbi patients	33
gene expression	33
post hoc	33
patient outcome	33
determined using	33
high dose	33
retrospective review	33
enrolled patients	33
chest tube	32
died within	32
thoracic trauma	32
scientific studies	32
treatment group	32
simplified acute	32
higher rate	32
early postoperative	32
kg day	32
frequently used	32
gas analysis	32
recent studies	32
femoral artery	32
random effects	32
protective effect	32
acute coronary	32
lung disease	32
controlled study	31
renal dysfunction	31
arterial lactate	31
tissue oxygen	31
mortality associated	31
high flow	31
days vs	31
bronchoalveolar lavage	31
quality improvement	31
niv failure	31
eff ective	31
high levels	31
see table	31
volume expansion	31
muscle weakness	31
day survival	31
icu survivors	31
inpatient mortality	31
support scientific	31
research support	31
pelvic fractures	31
rbc transfusion	31
surgical intensive	31
driving pressure	31
central nervous	31
surface area	31
shockable rhythm	31
high incidence	31
mixed venous	31
tract infection	31
surviving sepsis	31
activated protein	31
first time	31
respiratory syndrome	31
novel coronavirus	31
jugular bulb	31
retrospectively reviewed	30
family members	30
european countries	30
confidence intervals	30
decreased significantly	30
positive end	30
may reduce	30
respiratory diseases	30
tracheal intubation	30
selected patients	30
real time	30
prospectively studied	30
first three	30
aki stage	30
group received	30
prospective randomized	30
patients diagnosed	30
lung water	30
every patient	30
neurologic outcome	30
randomized trial	30
non invasive	30
outcome scale	30
previously reported	30
evaluated using	30
hours later	30
gold standard	30
poverty status	30
polytrauma patients	30
flail chest	30
splenic injury	30
required mechanical	30
spontaneous circulation	30
clinical presentation	30
statistically signifi	30
three different	30
male sex	30
minute ventilation	30
surgical management	30
vasoactive drugs	30
one patients	30
acute abdomen	29
patient underwent	29
even though	29
negative pressure	29
gram negative	29
altman analysis	29
world health	29
liver disease	29
fi ndings	29
old female	29
positive correlation	29
femoral neck	29
identify factors	29
recent years	29
inflammatory cytokines	29
labor market	29
study suggests	29
vena cava	29
cardiac surgical	29
primary objective	29
observational cohort	29
glycemic control	29
inotropic support	29
lung ultrasound	29
high rate	29
increased morbidity	29
monocentric study	29
current study	29
early detection	29
pulse pressure	29
multivariable logistic	29
lower respiratory	29
life expectancy	29
early phase	29
inspiratory pressure	29
major surgery	29
intervention group	29
brain tissue	29
co removal	29
surgical site	29
socioeconomic status	29
cerebral perfusion	29
time spent	28
unfavorable outcome	28
evaluate whether	28
brain damage	28
observation period	28
right heart	28
acute abdominal	28
extravascular lung	28
patients years	28
fi brinogen	28
calculated using	28
case fatality	28
pct levels	28
also found	28
response syndrome	28
continuous renal	28
protective ventilation	28
external fixation	28
crp levels	28
average length	28
citrate anticoagulation	28
standard care	28
weaning failure	28
trauma team	28
related complications	28
ischemic heart	28
included studies	28
beneficial effect	28
four groups	28
ecmo support	28
may contribute	28
discharged alive	28
plasma concentrations	28
older patients	28
analysis revealed	28
patients suffered	28
pulmonary oedema	27
hemodynamic stability	27
patient group	27
general population	27
operative management	27
group showed	27
steady state	27
group without	27
renal disease	27
confi rmed	27
days later	27
cirrhotic patients	27
bacterial infections	27
clinical parameters	27
influenza virus	27
functional status	27
times higher	27
intramedullary nailing	27
control study	27
hand hygiene	27
least hours	27
body temperature	27
renal impairment	27
statistically different	27
delayed diagnosis	27
comorbidity index	27
placebo group	27
improved survival	27
strongly associated	27
may provide	27
flow rate	27
transpulmonary thermodilution	27
organ support	27
medical patients	27
patients needed	27
klebsiella pneumoniae	27
mm patients	27
aspiration pneumonia	26
early identification	26
emergency physicians	26
acute circulatory	26
early mortality	26
group versus	26
retrospectively analyzed	26
organ failures	26
independent predictors	26
term outcome	26
immune system	26
time point	26
remaining patients	26
healthy controls	26
patient demographics	26
clinical decision	26
portal vein	26
necrosis factor	26
spinal cord	26
tissue damage	26
status epilepticus	26
trauma centre	26
cognitive dysfunction	26
penetrating trauma	26
considered statistically	26
bypass grafting	26
transthoracic echocardiography	26
icu staff	26
plateau pressure	26
wistar rats	26
lower extremity	26
negative bacteria	26
left ventricle	26
pediatric trauma	26
first week	26
chronic respiratory	26
stroke patients	26
median icu	26
time period	26
ml vs	26
immunocompromised patients	26
data regarding	26
type i	26
scoring systems	26
bed icu	26
burn injury	26
serum concentrations	25
map mmhg	25
artery pressure	25
mortality ratio	25
cantly higher	25
major complications	25
apache score	25
chronic renal	25
low tidal	25
least days	25
disseminated intravascular	25
trauma centers	25
perfusion pressure	25
statistical difference	25
new york	25
kg hour	25
filtration rate	25
spontaneously breathing	25
level i	25
well known	25
poor outcomes	25
patients ventilated	25
survival rates	25
infl ammation	25
plasma concentration	25
grant acknowledgement	25
base excess	25
flow cytometry	25
common complication	25
income countries	25
breathing trial	25
significantly improved	25
diaphragm dysfunction	25
significant risk	25
tracheostomy tube	25
results show	25
post operative	25
induced lung	25
rank test	25
main causes	25
critical patients	25
undergoing cardiac	25
clinical studies	25
admitted patients	25
ventricular function	25
time course	24
demographic characteristics	24
patients compared	24
mcg kg	24
intravascular coagulation	24
fluid loading	24
dead space	24
outcome measure	24
foreign body	24
infectious disease	24
chi square	24
prospective studies	24
air pollution	24
peripheral blood	24
normal values	24
identified patients	24
postoperative course	24
thrombin generation	24
acute ischemic	24
inhalation injury	24
ex vivo	24
examination revealed	24
regression models	24
coronary angiography	24
closed reduction	24
adrenal insufficiency	24
normal saline	24
arrest patients	24
venous oxygen	24
health problem	24
eligible patients	24
subgroup analysis	24
positive airway	24
severely ill	24
serum lactate	24
death rates	24
france correspondence	24
months later	24
mean icp	24
endothelial cell	24
ventilator associated	24
twelve patients	24
hours post	24
observational studies	24
health organization	24
ill children	24
improve patient	24
reference introduction	24
charlson comorbidity	24
medical university	24
chronic health	24
target range	24
analysis using	24
expiratory flow	23
patient age	23
cerebral blood	23
host response	23
one third	23
nosocomial pneumonia	23
glucose levels	23
articular surface	23
month mortality	23
ivc diameter	23
adverse outcomes	23
human capital	23
ug ml	23
therapeutic management	23
level trauma	23
vascular injury	23
trauma system	23
burned patients	23
main cause	23
ill patient	23
type ii	23
global mortality	23
inflammatory markers	23
respiratory infections	23
also recorded	23
acinetobacter baumanii	23
shaft fractures	23
animal models	23
mental health	23
infusion rate	23
classified according	23
controlled ventilation	23
regional hospital	23
patients within	23
old woman	23
emergency laparotomy	23
low risk	23
mechanical power	23
chest compressions	23
patient admitted	23
care hospital	23
factors related	23
sepsis septic	23
eff ectiveness	23
sepsis campaign	23
arterial oxygen	23
fold higher	23
saps score	23
study performed	23
overall survival	23
high doses	23
grade iii	23
neurological deficit	23
congestive heart	23
abdominal ct	23
bone marrow	23
children aged	23
outcome data	23
multiple regression	23
significant changes	23
bypass surgery	22
fluid therapy	22
th percentile	22
cervical spine	22
hypovolemic shock	22
following parameters	22
good outcome	22
vein thrombosis	22
multidisciplinary team	22
pulmonary infection	22
twenty patients	22
per cent	22
data obtained	22
associated injuries	22
primary care	22
music therapy	22
artery disease	22
clinically significant	22
elective surgery	22
diagnostic accuracy	22
written informed	22
trauma patient	22
first postoperative	22
average duration	22
hospital icu	22
intestinal obstruction	22
underlying disease	22
patient data	22
body surface	22
poor neurological	22
mechanical ventilator	22
flow nasal	22
mortality data	22
receive either	22
emergency care	22
plasminogen activator	22
health status	22
within minutes	22
mg ml	22
multiorgan failure	22
nitrogen balance	22
organ function	22
major abdominal	22
repeated measures	22
pelvic fracture	22
adult icu	22
noninvasive ventilation	22
small sample	22
case reports	22
laboratory tests	22
cell death	22
right ventricle	22
randomized study	22
clinical study	22
cortisol levels	22
risk score	22
loading dose	22
pulse contour	22
animal model	22
mortality prediction	22
mortality compared	22
defined according	22
patients survived	22
excess deaths	22
low dose	22
peep level	22
fluid overload	22
remains unclear	22
continuous variables	22
well tolerated	22
sublingual microcirculation	22
dependent variable	22
machine learning	21
six months	21
pandemic influenza	21
insulin infusion	21
comatose patients	21
inferior vena	21
fatality rate	21
significantly longer	21
economic history	21
took place	21
mean blood	21
higher levels	21
muscle mass	21
missing data	21
diaphragm thickness	21
patients discharged	21
outcome measures	21
pregnant women	21
published data	21
carotid artery	21
iu ml	21
apache iii	21
weight heparin	21
mean follow	21
several studies	21
icu days	21
serious complications	21
respiratory variations	21
care med	21
treated conservatively	21
negative bacilli	21
severe patients	21
significant morbidity	21
small number	21
linear mixed	21
longer duration	21
major role	21
traumatic stress	21
requiring icu	21
patients whose	21
volume index	21
ecmo patients	21
secondary endpoints	21
blood product	21
phase ii	21
remained unchanged	21
organ dysfunctions	21
infl uence	21
group iii	21
cognitive impairment	21
mean saps	21
categorical variables	21
mesenteric ischemia	21
gastrointestinal tract	21
tract infections	21
higher rates	21
group vs	21
fluid bolus	21
year survival	21
less educated	21
term mortality	21
patients met	21
second day	21
vascular permeability	21
traffic accident	21
systemic vascular	21
frozen plasma	21
cardiac dysfunction	21
identify risk	21
term outcomes	21
previous study	21
tissue perfusion	21
myocardial dysfunction	21
abbreviated injury	21
health system	21
making process	21
head injuries	21
iu kg	21
hospital death	21
initial management	20
propensity score	20
tissue injury	20
therapeutic interventions	20
nasogastric tube	20
dysfunction syndrome	20
antibiotic prophylaxis	20
characteristic curve	20
failure rate	20
laboratory findings	20
plasma lactate	20
tumor necrosis	20
admission diagnosis	20
cerebral artery	20
burn center	20
median sofa	20
vt ml	20
general intensive	20
results patients	20
patient groups	20
experimental study	20
mortality patterns	20
frequent cause	20
i trauma	20
female patients	20
clinical variables	20
one month	20
requiring intensive	20
respiratory insufficiency	20
site infection	20
severe brain	20
good correlation	20
syndrome coronavirus	20
sepsis group	20
molecular weight	20
septic complications	20
breathing pattern	20
first months	20
randomized clinical	20
clinical diagnosis	20
distal radius	20
serum samples	20
pelvic ring	20
chart review	20
control groups	20
suspected infection	20
beneficial effects	20
drug resistant	20
polymerase chain	20
bed medical	20
open abdomen	20
hazard ratio	20
community acquired	20
continuous monitoring	20
severe respiratory	20
trauma cases	20
three months	20
oxygen transport	20
future studies	20
acute stroke	20
worse outcomes	20
significantly correlated	20
variables associated	20
growth factor	20
also associated	20
several factors	20
randomised controlled	20
catheter related	20
potential risk	20
thirty patients	20
rapid response	20
life care	20
ca patients	20
past years	20
postoperative care	20
prognostic factor	20
patients submitted	20
kg hr	20
successful weaning	20
clinical condition	20
failure requiring	20
findings suggest	20
trend towards	20
early stage	20
xa activity	20
without significant	20
negative correlation	20
diabetic ketoacidosis	20
control patients	20
diaphragmatic hernia	20
respiratory infection	20
retrospective case	20
two hours	20
cerebral oxygenation	19
mean sd	19
market share	19
undergoing ssrf	19
cardiopulmonary arrest	19
health evaluation	19
patients according	19
clinical conditions	19
clinical status	19
functional outcomes	19
mean hospital	19
trauma mechanism	19
odds ratios	19
four cases	19
predicted body	19
roc curves	19
improve survival	19
supportive care	19
carbon monoxide	19
single centre	19
medical students	19
hospital los	19
oxygenation index	19
hemodynamically unstable	19
thromboembolic diseases	19
ventilation time	19
initial treatment	19
high energy	19
hypoxemic patients	19
hemodynamic variables	19
often associated	19
bloodstream infection	19
healthcare professionals	19
gastric emptying	19
hemodynamic status	19
prothrombin time	19
one week	19
sectional study	19
icu setting	19
transition theory	19
head ct	19
international guidelines	19
chronic liver	19
false positive	19
daily living	19
risk stratification	19
right side	19
low levels	19
trauma surgery	19
median iss	19
isolated bacteria	19
may cause	19
oxygen extraction	19
decompressive craniectomy	19
aki patients	19
volume resuscitation	19
cardiac arrests	19
probably due	19
days post	19
patient presented	19
two days	19
therapeutic intervention	19
neutropenic patients	19
severe complications	19
multivariate regression	19
infection rate	19
electronic medical	19
died due	19
great depression	19
high rates	19
ards group	19
baseline values	19
investigated whether	19
resistant bacteria	19
data show	19
spontaneous ventilation	19
directed therapy	19
external fixator	19
chronic diseases	19
survival analysis	19
ammatory response	19
organ injury	19
chain reaction	19
icu physicians	19
better outcome	19
airway pressures	19
fracture healing	19
remains high	19
excluded patients	19
coronary syndrome	19
stress disorder	18
center retrospective	18
pulmonary function	18
total body	18
main objective	18
weight loss	18
pressure mmhg	18
age range	18
independent factors	18
university hospitals	18
frequent complication	18
prospectively included	18
middle cerebral	18
type diabetes	18
blood transfusions	18
highly significant	18
group patients	18
icu population	18
gestational age	18
nutritional status	18
complications related	18
previously described	18
percutaneous tracheostomy	18
cohort studies	18
injury scale	18
traffic accidents	18
secondary outcome	18
icu readmission	18
preliminary data	18
th century	18
mass casualty	18
transit time	18
serious adverse	18
assessment method	18
systolic arterial	18
high frequency	18
inhaled nitric	18
protocol group	18
operating characteristics	18
younger patients	18
hematological malignancies	18
group treated	18
vessel density	18
liver injury	18
glucose level	18
phase i	18
acetabular fractures	18
using two	18
normal subjects	18
icu nurses	18
patients enrolled	18
male gender	18
two studies	18
york city	18
dawley rats	18
main reason	18
clinical setting	18
routine use	18
mv duration	18
multiple myeloma	18
underwent surgery	18
three times	18
worse prognosis	18
available data	18
hospital care	18
blunt chest	18
life decisions	18
arterial hypertension	18
humeral fractures	18
factors affecting	18
arterial ph	18
skeletal muscle	18
different groups	18
nasal cannula	18
cox model	18
global burden	18
diffi cult	18
peep cmh	18
year follow	18
elective cardiac	18
active bleeding	18
treatment options	18
arterial catheters	18
glomerular filtration	18
bowel obstruction	18
single dose	18
valve replacement	18
venous thrombosis	18
insulin therapy	18
escherichia coli	18
study found	18
neurological complications	18
different types	18
pass success	17
fresh frozen	17
rate among	17
statistical differences	17
current practice	17
tertiary referral	17
injury score	17
prolonged icu	17
mortality inequalities	17
secondary infections	17
preliminary study	17
solid organ	17
acute liver	17
diabetic patients	17
peep levels	17
burn unit	17
tube placement	17
higher apache	17
infection control	17
one study	17
bacterial resistance	17
pk pd	17
vasopressor support	17
cantly lower	17
acquired weakness	17
fibrinogen concentrate	17
venous catheters	17
days following	17
low molecular	17
primary repair	17
death rate	17
many patients	17
patients studied	17
associated risk	17
may occur	17
life threatening	17
angiotensin ii	17
lactic acid	17
stable patients	17
two years	17
i min	17
mainly due	17
maternal mortality	17
invasive procedures	17
phase iii	17
unfractionated heparin	17
fecal peritonitis	17
cardiac failure	17
operative treatment	17
total mortality	17
study patients	17
septic group	17
base deficit	17
sepsis syndrome	17
severe septic	17
death among	17
acute pulmonary	17
early sepsis	17
femoral vein	17
acute mesenteric	17
trend toward	17
median apache	17
venous thromboembolism	17
patients respectively	17
low mortality	17
qsofa score	17
time interval	17
emergency surgical	17
thrombolytic therapy	17
related infections	17
three cases	17
first two	17
hospital survival	17
nerve palsy	17
first pass	17
term survival	17
using spss	17
male patient	17
information system	17
first study	17
predict fluid	17
acquired infections	17
abdominal cavity	17
risk group	17
acute poisoning	17
remained stable	17
grade iv	17
early recognition	17
inhospital mortality	17
liver cirrhosis	17
laboratory data	17
final diagnosis	17
low cardiac	17
trochanteric fractures	17
penetrating abdominal	17
fixed effects	17
wedge pressure	17
curve analysis	17
intensive insulin	17
neuromuscular blockade	17
uid balance	17
within months	17
onset vap	17
pulmonary complications	17
clinical results	17
cord injury	17
predicting mortality	17
emergency service	17
among hospitalized	17
medical service	17
icu day	17
upper extremity	17
much higher	17
healthcare costs	17
undergoing elective	17
reduced mortality	17
invasive aspergillosis	17
viral infection	17
motor vehicle	17
sensitivity analysis	17
mean difference	17
road traffic	17
icu treatment	17
often used	17
right atrium	17
screw fixation	17
ml cmh	17
significant higher	17
old patients	17
may benefit	17
plate osteosynthesis	16
pulmonary tuberculosis	16
wide range	16
survivor group	16
small intestine	16
mg day	16
first attempt	16
electronic health	16
lung compliance	16
depression scale	16
months period	16
developing countries	16
converting enzyme	16
extracorporeal life	16
related factors	16
surgical emergencies	16
per group	16
care admission	16
acute heart	16
past medical	16
induced pulmonary	16
patients experienced	16
seven days	16
antibiotic prescription	16
hiv aids	16
continuous positive	16
following criteria	16
acute severe	16
drug administration	16
amino acids	16
higher among	16
pivotal role	16
lower extremities	16
invasive candidiasis	16
data base	16
patients older	16
organ systems	16
hospitalized covid	16
weaning protocol	16
blood fl	16
ultrasound guidance	16
ventilator days	16
empirical antibiotic	16
induced coagulopathy	16
respiratory effort	16
hepatic encephalopathy	16
early vap	16
lv systolic	16
kdigo criteria	16
tranexamic acid	16
lung elastance	16
routinely used	16
main reasons	16
prediction model	16
constant flow	16
tissue hypoxia	16
first hour	16
natriuretic peptide	16
early pn	16
physiological parameters	16
years period	16
thoracic surgery	16
penetrating injuries	16
initial dose	16
gas flow	16
low doses	16
infection rates	16
clinical use	16
study groups	16
care system	16
male wistar	16
increasingly used	16
significantly elevated	16
ventricular ejection	16
rater reliability	16
electrical activity	16
risk assessment	16
th postoperative	16
care center	16
useful tool	16
fluid management	16
mean total	16
epidemiological characteristics	16
using data	16
four times	16
laboratory parameters	16
rst hours	16
years ago	16
care department	16
cerebral ischemia	16
icu care	16
cerebral oxygen	16
also significantly	16
using standard	16
energy expenditure	16
neck fractures	16
nursing care	16
antibiotic susceptibility	16
lung protective	16
venous return	16
data included	16
higher severity	16
neurological status	16
hospital outcome	16
patients will	16
femoral fracture	16
transfusion requirements	16
months follow	16
response rate	16
rv function	16
without sepsis	16
every day	16
differential diagnosis	16
whole body	16
patient comfort	16
treatment results	16
bloodstream infections	16
non survivors	16
respiratory disease	16
tracheal pressure	16
patients operated	16
glucose control	16
adhesion molecules	16
main results	16
recruitment maneuver	16
early warning	16
following variables	16
better survival	16
results showed	16
unstable patients	16
human albumin	16
surgical technique	16
influenza infection	16
among covid	16
human serum	16
remains controversial	16
higher number	16
among icu	16
icu patient	16
mean airway	15
reactive oxygen	15
prospective data	15
adult trauma	15
randomized trials	15
mean sofa	15
diagnostic criteria	15
lung mechanics	15
severe aecopd	15
total patients	15
young people	15
severe complication	15
mixed effects	15
chest injuries	15
adverse outcome	15
outcomes included	15
standard therapy	15
daily mortality	15
mean icu	15
intravenous infusion	15
regression analyses	15
oleic acid	15
appropriate treatment	15
interval ci	15
poorly understood	15
passive leg	15
ill adults	15
weight bearing	15
tb patients	15
therapeutic strategy	15
multicenter cohort	15
study using	15
partial thromboplastin	15
inspiratory effort	15
icu ventilators	15
femoral head	15
sixteen patients	15
using logistic	15
air bronchogram	15
mean pulmonary	15
serum pct	15
neurological deterioration	15
continuous data	15
postoperative days	15
mortality benefit	15
cerebrospinal fluid	15
mean number	15
complications associated	15
severe hypoxemia	15
ideal body	15
respiratory acidosis	15
experimental sepsis	15
conventional ventilation	15
failure due	15
kidney function	15
literature review	15
lung regions	15
reach statistical	15
cranial trauma	15
blunt abdominal	15
statistical significant	15
patients infected	15
chronic pain	15
clinical experience	15
palliative care	15
lung biopsy	15
hemodynamic measurements	15
care setting	15
alcohol consumption	15
antimicrobial resistance	15
microcirculatory perfusion	15
hospital anxiety	15
important cause	15
anova test	15
brain trauma	15
predictive values	15
period patients	15
candida albicans	15
subclavian vein	15
secondary analysis	15
following icu	15
results obtained	15
weaning process	15
identified using	15
also collected	15
cardiac troponin	15
modifi ed	15
sedative drugs	15
oral anticoagulants	15
patients introduction	15
first episode	15
mixed icu	15
vascular tone	15
control measures	15
postoperative morbidity	15
worse outcome	15
functional results	15
specifi city	15
negative impact	15
positive culture	15
left side	15
line treatment	15
japan introduction	15
smooth muscle	15
reperfusion injury	15
smartcare ps	15
upper gi	15
ganz catheter	15
comparative study	15
log rank	15
study demonstrated	15
pain evaluation	15
significant proportion	15
adult respiratory	15
clinical criteria	15
health outcomes	15
strong correlation	15
four hours	15
retrospective single	15
significant relationship	15
randomly allocated	15
two methods	15
multivariable analysis	15
pain management	15
urea nitrogen	15
per minute	15
important factor	15
deep vein	15
different levels	15
female ratio	15
consecutive adult	15
lactic acidosis	15
study design	15
female sex	15
regional citrate	15
contour analysis	15
thirteen patients	15
five cases	15
explanatory variables	15
cox regression	15
group included	15
least two	15
fatty acids	15
myocardial ischemia	15
first line	15
patient management	15
severe infections	15
invasive method	15
prospective multicenter	15
serum na	15
bronchial secretions	15
month follow	15
children admitted	15
lower limb	15
data concerning	15
hemoglobin level	15
first dose	15
lung tissue	15
care services	15
volume controlled	15
slightly higher	15
literature search	14
good neurological	14
epidural analgesia	14
epidemiological data	14
introduction acute	14
better understanding	14
shock requiring	14
room air	14
ventilation duration	14
induced changes	14
total respiratory	14
underlying malignancy	14
white cell	14
preload responsiveness	14
developed vap	14
packed red	14
noncancer patients	14
end point	14
also noted	14
newly developed	14
favorable neurologic	14
statistical analyses	14
associated factors	14
coronary heart	14
type iii	14
diagnostic performance	14
infant mortality	14
retrospectively analysed	14
biological data	14
temperature management	14
sigmoid volvulus	14
receiving mechanical	14
potential donors	14
uric acid	14
clot formation	14
cd cd	14
trauma centres	14
myocardial injury	14
three years	14
last decades	14
differed significantly	14
femur fractures	14
adverse effect	14
fourteen patients	14
rv lv	14
diagnostic value	14
statistically significantly	14
proximal femoral	14
similar results	14
may represent	14
elevated renin	14
mean score	14
outcomes among	14
wound infection	14
lipid peroxidation	14
clinical suspicion	14
effective treatment	14
organ donors	14
consecutive days	14
peptic ulcer	14
evidence suggests	14
decision support	14
review board	14
care management	14
showed good	14
care team	14
successfully treated	14
treatment groups	14
open heart	14
chest radiograph	14
clinical impact	14
operative complications	14
conventional treatment	14
study demonstrates	14
less likely	14
red cell	14
french icus	14
lps group	14
newly diagnosed	14
stay days	14
ethical committee	14
procedural sedation	14
prehospital setting	14
adverse event	14
pct level	14
data showed	14
two independent	14
exogenous surfactant	14
secondary objective	14
septic animals	14
significant impact	14
sepsis induced	14
immediate postoperative	14
rescue therapy	14
continuous veno	14
multiple logistic	14
ventricular dysfunction	14
cecal ligation	14
massive pulmonary	14
retrospectively collected	14
total hip	14
rat model	14
rank correlation	14
oral care	14
found significant	14
infrared spectroscopy	14
leg raising	14
patients following	14
antimicrobial treatment	14
fracture type	14
function tests	14
northern italy	14
past pandemics	14
care physicians	14
good predictor	14
patient days	14
fluid removal	14
global health	14
patient populations	14
ohca patients	14
median number	14
study based	14
hospital admissions	14
critical ill	14
retrospective chart	14
analysis demonstrated	14
crit care	14
term follow	14
mixed medical	14
therapeutic range	14
healthcare use	14
oxygen supply	14
systolic dysfunction	14
bleeding complications	14
data set	14
pearson correlation	14
patients due	14
following data	14
platelet counts	14
serum concentration	14
antibiotic administration	14
underwent surgical	14
may influence	14
positive results	14
fungal infection	14
hypoxemic respiratory	14
tracheal tube	14
healthy people	14
squared test	14
stem cell	14
pulse oximetry	14
benefi ts	14
south africa	14
hemodynamic effects	14
traumatic injuries	14
study introduction	14
underwent cardiac	14
splenic injuries	14
rate variability	14
inhibitory concentration	14
mortality trends	14
oxygen tension	14
hepatic failure	14
medical team	14
also compared	14
also performed	14
identifi cation	14
postoperative patients	14
direct examination	14
medical record	14
rib fracture	14
bronchogram sign	14
colon anastomosis	14
intravascular volume	14
also showed	14
increased levels	14
improve outcomes	14
significantly greater	14
study protocol	14
longer hospital	14
risk surgical	14
coagulation factors	14
main outcome	14
significant mortality	14
chest radiography	14
weaning criteria	14
liquid chromatography	14
femur fracture	14
term effects	14
early goal	14
general wards	14
analysed data	14
high blood	14
pulmonary contusion	14
pulse rate	14
computerized tomography	14
general anaesthesia	14
fungal infections	14
brain dysfunction	14
adipose tissue	13
inspiratory flow	13
mean iss	13
operative period	13
bone defect	13
endothelial function	13
favorable outcome	13
initial resuscitation	13
retrospective audit	13
hematologic malignancies	13
neutrophil activation	13
bowel sounds	13
icu team	13
binding protein	13
troponin i	13
among critically	13
clinical significance	13
may play	13
early mobilization	13
term exposure	13
blood urea	13
living conditions	13
effects model	13
inspired oxygen	13
acquired infection	13
ankle fractures	13
first year	13
thromboplastin time	13
kidney transplantation	13
cerebral performance	13
two consecutive	13
common practice	13
humeral shaft	13
blood sugar	13
cardiovascular risk	13
stage renal	13
cerebrovascular disease	13
continuously monitored	13
transplant recipients	13
plate fixation	13
hospital acquired	13
benefi cial	13
good results	13
chest compression	13
gas parameters	13
online survey	13
high quality	13
longer icu	13
patients require	13
higher doses	13
whole population	13
activated partial	13
chronic heart	13
venous catheterization	13
care nurse	13
medical surgical	13
solid tumors	13
treatment protocol	13
received mechanical	13
diastolic volume	13
drug monitoring	13
groups i	13
random forest	13
urinary catheter	13
unit patients	13
high grade	13
ct head	13
lower risk	13
particulate matter	13
recombinant human	13
standardized mortality	13
pain score	13
resistant staphylococcus	13
neuromuscular blockers	13
plasma samples	13
hong kong	13
experimental model	13
may develop	13
prognostic models	13
oslo university	13
vegetative state	13
clinical severity	13
aki group	13
blunt splenic	13
national trauma	13
laboratory values	13
advanced age	13
gastrointestinal bleeding	13
allowed us	13
hours following	13
immune responses	13
endothelial damage	13
proximal femur	13
mortality following	13
post traumatic	13
still remains	13
every minutes	13
hiv infection	13
low flow	13
qs qt	13
insulin resistance	13
screening tool	13
also observed	13
early post	13
committee approval	13
per hour	13
ct scanning	13
necrotizing pancreatitis	13
quality control	13
cfu ml	13
open surgery	13
demographic variables	13
injury mechanism	13
identifying patients	13
prowess trial	13
kcal kg	13
year average	13
porcine model	13
acid levels	13
developed septic	13
tube thoracostomy	13
aortic cross	13
traumatic injury	13
clinical manifestations	13
major adverse	13
extracorporeal circulation	13
apache scores	13
performance category	13
last months	13
radial nerve	13
therapeutic drug	13
blood coagulation	13
significantly better	13
igs ii	13
methods used	13
clinical evaluation	13
respiratory depression	13
spiking mortality	13
transesophageal echocardiography	13
candida species	13
serum sodium	13
first period	13
delta pco	13
volume ventilation	13
post cardiac	13
family satisfaction	13
early administration	13
treated surgically	13
surgical emergency	13
descriptive statistics	13
severe infection	13
less severe	13
vascular access	13
primary end	13
immune cells	13
treatment option	13
sodium lactate	13
platelet aggregation	13
patients remains	13
future research	13
renal insufficiency	13
broad spectrum	13
susceptibility testing	13
hospital setting	13
breathing patients	13
lactate clearance	13
gram positive	13
pain intensity	13
pandemic period	13
consecutively admitted	13
dead patients	13
known risk	13
energy trauma	13
institutional review	13
effective method	13
hospital universitario	13
individual patient	13
volume curve	13
mean pao	13
score ii	13
hypercapnic respiratory	13
resuscitation room	13
may impact	13
video laryngoscope	13
hemorrhagic stroke	13
conventional mechanical	13
young patients	13
copd exacerbation	13
hematological malignancy	13
flow oxygen	13
patient required	13
good clinical	13
retrospectively studied	13
common reason	13
baseline measurements	13
urinary output	13
per se	13
total bilirubin	13
emergent surgery	13
pao mmhg	13
new zealand	13
medical literature	13
drug therapy	13
organ damage	13
median value	13
circulatory shock	13
cvd mortality	13
thrombotic complications	13
fl uids	13
inversely correlated	13
refractory cardiac	13
clinical symptoms	13
treated using	13
predict outcome	13
last decade	13
sham group	13
anticoagulant therapy	13
organ system	13
conducted using	13
min vs	13
secondary objectives	13
abdominal injuries	13
influenza vaccination	13
received either	13
haematological malignancy	13
ct findings	13
done using	13
lv dysfunction	13
distal humeral	12
patients scheduled	12
crypt cells	12
requiring renal	12
treatment modality	12
nasal oxygen	12
total parenteral	12
stimulating factor	12
arterial oxygenation	12
analyzed patients	12
major risk	12
much lower	12
population density	12
patients including	12
individual patients	12
ill adult	12
general surgeon	12
activity assay	12
results among	12
recent data	12
lung function	12
early stages	12
anatomical reduction	12
using clinical	12
orotracheal intubation	12
antibiotic use	12
false negative	12
coeffi cient	12
cardiac injury	12
almost half	12
primary survey	12
larger studies	12
sedated patients	12
seventeen patients	12
spectrum antibiotics	12
young adults	12
treat patients	12
good functional	12
immune suppression	12
two pts	12
vascular resistances	12
clot microstructure	12
prognostic marker	12
open lung	12
particle flow	12
year study	12
bypass graft	12
antithrombotic drugs	12
medical conditions	12
cell surface	12
mann whitney	12
significant change	12
study comparing	12
combination therapy	12
one day	12
performed within	12
performance status	12
pg kg	12
dosing regimens	12
urban areas	12
assisted ventilation	12
sum test	12
daily practice	12
mean dose	12
superoxide dismutase	12
urine samples	12
training course	12
hemodynamic data	12
leading causes	12
non parametric	12
cumulative mortality	12
local ethics	12
cardiothoracic surgery	12
administered intravenously	12
transfusion requirement	12
major public	12
systolic pressure	12
clinical pulmonary	12
pulmonary gas	12
icu beds	12
consensus conference	12
frail patients	12
kingdom critical	12
using different	12
one group	12
albumin group	12
severe aki	12
alcohol abuse	12
hip fractures	12
frequently associated	12
fi eld	12
standard treatment	12
surgically treated	12
disease control	12
also studied	12
serious infections	12
showed increased	12
pressure monitoring	12
st january	12
third day	12
found statistically	12
quantitative analysis	12
transcranial doppler	12
estimated using	12
mathematical model	12
late mortality	12
patients reported	12
positive fluid	12
respiratory complications	12
polytraumatized patients	12
wet dry	12
commercially available	12
initial rhythm	12
magnetic resonance	12
national institutes	12
hour period	12
ischemia reperfusion	12
invasive fungal	12
systemic infl	12
lst limitation	12
early albumin	12
still alive	12
significantly shorter	12
recent study	12
first admission	12
time constant	12
mechanical properties	12
cutoff value	12
electronic patient	12
likely due	12
initial blood	12
head injured	12