bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram frequency
inflammatory syndrome291
multisystem inflammatory277
kawasaki disease140
coronavirus disease125
pediatric patients85
acute respiratory76
case series65
coronary artery64
severe covid60
systematic review52
united states51
respiratory syndrome49
new york49
severe acute47
intensive care46
temporally associated44
cardiac involvement43
shock syndrome42
cytokine storm42
clinical characteristics41
syndrome coronavirus39
pediatric covid39
novel coronavirus37
syndrome temporally36
cohort study35
cardiac dysfunction35
inflammatory markers35
respiratory distress33
clinical presentation33
hyperinflammatory shock31
heart failure30
toxic shock30
imaging findings30
inflammatory multisystem29
like disease29
intravenous immunoglobulin29
immune response29
doc id28
clinical features28
cord uid28
reactive protein28
multisystem syndrome28
distress syndrome26
pediatric population25
hospitalized patients25
gastrointestinal symptoms24
macrophage activation23
rights reserved23
disease control23
task force22
respiratory failure22
care unit21
immune system21
associated multisystem21
observational cohort21
respiratory symptoms21
abdominal pain21
pediatric intensive21
activation syndrome20
previously healthy20
immune responses19
pediatric inflammatory19
ng ml19
critically ill19
severe disease18
left ventricular18
natriuretic peptide18
risk factors18
viral load17
mechanical ventilation17
among children17
acute heart17
severe illness17
less severe17
ventricular dysfunction17
severe kawasaki17
mg kg17
york city17
erythrocyte sedimentation16
respiratory tract16
pg ml16
case report16
york state16
social distancing15
italian epicentre15
observational study15
case reports15
healthy children15
polymerase chain15
world health15
sedimentation rate15
elevated inflammatory15
health organization15
acute phase15
ejection fraction15
chain reaction15
mg dl14
system inflammatory14
critical care14
seasonal hcovs14
acute kidney14
artery dilation14
less likely14
data collection14
cytokine release14
global sars14
peer review14
following sars14
paediatric multisystem14
artery aneurysms14
adult covid14
case definition14
syndrome related14
kidney injury14
children presenting13
hemophagocytic lymphohistiocytosis13
severe cases13
vertical transmission13
severe respiratory13
ill children13
organ dysfunction13
granted medrxiv13
reported cases13
author funder13
immune dysregulation13
coronavirus infection13
young children13
laboratory evidence13
upper respiratory13
medical information13
systolic function12
treated patients12
infectious disease12
children may12
infectious diseases12
inflammatory disease12
viral infection12
laboratory findings12
emergency department12
pediatric cases12
positive sars12
confirmed cases12
higher risk12
systemic inflammation12
copyright holder12
care units12
posted june11
type natriuretic11
laboratory markers11
disease severity11
asymptomatic children11
term management11
myocardial dysfunction11
clinical manifestations11
hyperinflammatory syndrome11
version posted11
inflammatory response11
mis medis11
ventricular function11
confirmed covid11
mucosal changes11
heart disease11
physical activity10
blood cell10
like multisystem10
reuse allowed10
median age10
informed consent10
many patients10
septic shock10
organ systems10
like illness10
allowed without10
without permission10
health professionals10
neuropsychiatric symptoms10
hospitalized children10
pediatric multisystem10
acute myocarditis10
clinical symptoms10
magnetic resonance10
cardiac injury10
organ involvement10
increased risk10
scientific statement10
hospital day10
thoracic imaging10
diagnostic criteria9
clinical course9
retrospective cohort9
converting enzyme9
atypical kawasaki9
seasonal coronaviruses9
release syndrome9
pediatric mis9
small number9
health care9
standard deviation9
extracorporeal membrane9
diagnostic evaluation9
organ system9
pandemic multisystem9
oropharyngeal swabs9
immunomodulatory treatment9
child health9
necrosis factor9
paediatric inflammatory9
prospective observational9
without rash9
cardiogenic shock9
membrane oxygenation9
neutralizing activity9
artery aneurysm9
patients infected9
cardiac manifestations9
glass opacities9
young adults9
cardiac mri9
mental health8
clinical signs8
different clinical8
immune suppression8
system involvement8
neutralizing antibodies8
like lesions8
platelet count8
hyperinflammatory state8
ill patients8
dose aspirin8
patients without8
authors declare8
met criteria8
clinical trials8
novel virus8
acute pediatric8
lactate dehydrogenase8
positive rt8
lower respiratory8
mimicking kawasaki8
may also8
resonance imaging8
proinflammatory cytokines8
cell count8
elevated levels8
vast majority8
gene expression8
receptor antagonist8
blood pressure8
novel case8
united kingdom8
acute cardiac8
neonates born8
children diagnosed8
information system8
tumor necrosis8
respiratory disease8
lv dysfunction8
seasonal hcov7
initial reports7
mucocutaneous manifestations7
tracheal aspirates7
one patient7
epidemiological characteristics7
typical pediatric7
kg day7
adult patients7
systemic hyperinflammation7
second dose7
liver function7
milder cases7
term outcomes7
cardiac imaging7
possible causes7
public health7
nervous system7
antibody responses7
infection admitted7
years old7
complete blood7
medical conditions7
coronary arteries7
viral loads7
data interpretation7
supportive care7
laboratory values7
disease shock7
affected children7
viral transmission7
expert opinion7
less frequent7
urgent care7
confirmed sars7
chest radiographs7
mildly symptomatic7
american heart7
white blood7
inflammatory cytokines7
canadian pediatric7
treatment guidelines7
future studies7
respiratory viruses7
mortality rate7
systemic inflammatory7
respiratory infection7
gi symptoms7
early infection7
patients may7
persistent fever7
preliminary report7
children aged7
may help7
recent sars7
systematic reviews7
age group7
african american7
single center7
congenital heart7
sample collection7
infection control7
symptomatic infection6
maternal sars6
mean age6
cardiovascular disease6
weight heparin6
reports suggest6
severe symptoms6
artery abnormalities6
social contacts6
overlapping features6
disease pathogenesis6
least one6
may explain6
blood count6
artery dilatation6
function tests6
oral mucosal6
multicenter study6
platelet counts6
mucocutaneous disease6
healthcare providers6
previously reported6
study design6
storm syndrome6
infected children6
samples collected6
viral infections6
elevated troponin6
coronary aneurysms6
immunological features6
assessment tool6
coronary involvement6
immunomodulatory therapy6
inclusion criteria6
ab responses6
multisystem organ6
interquartile range6
accepted article6
requiring hospitalization6
better understanding6
children covid6
respiratory support6
respiratory syncytial6
heart association6
adult population6
center experience6
two patients6
human coronavirus6
many children6
children years6
better prognosis6
cervical lymphadenopathy6
immediately stored6
convalescent plasma6
multicentre cohort6
specimen collection6
computed tomography6
vital signs6
syncytial virus6
patients will6
less frequently6
myocardial involvement6
factors associated6
erythema multiforme6
lessons learned6
pcr testing6
fluid resuscitation6
data regarding6
health center6
first case6
ventricular systolic6
patients presenting6
significantly elevated6
mucocutaneous findings6
north america6
narrative review6
available data6
pulmonary emboli6
american college6
sore throat6
clinical team6
severe course6
underlying medical6
cystic fibrosis6
thrombotic complications6
mental status6
innate immune6
molecular weight6
troponin levels6
pediatric critical6
low molecular6
contact tracing6
one death6
information systems6
age range6
incomplete kd6
typical acute6
existing medical6
kd patients6
children associated6
severe pulmonary5
chronic disease5
seropositive children5
profound lymphopenia5
low dose5
inotropic support5
induced kawasaki5
provide guidance5
central nervous5
response may5
children will5
conduction abnormalities5
shed light5
previously described5
laboratory results5
children shows5
clinical presentations5
chronic patients5
lower platelet5
dysfunction markers5
secondary hemophagocytic5
systolic dysfunction5
epidemiological study5
myocardial damage5
may contribute5
natural killer5
new england5
high levels5
juvenile idiopathic5
reported patients5
severe manifestations5
reverse transcriptase5
will need5
aleksandar milenkovic5
syndrome associated5
proposed management5
skin findings5
factors driving5
novel multisystem5
infect dis5
acute covid5
confirmed pediatric5
acute myocardial5
supplementary material5
cardiac magnetic5
storm syndromes5
skin lesions5
fetal development5
sample size5
depressed ejection5
although children5
icu admission5
human coronaviruses5
clinical guidance5
biorepository will5
trained immunity5
worldwide cases5
quality assessment5
mild disease5
common clinical5
hbss minus5
global pandemic5
cdc covid5
increased incidence5
thromboembolic complications5
growing number5
critical cases5
laboratory testing5
multisystem involvement5
institutional review5
royal college5
pediatric acute5
remains unclear5
prothrombin time5
coronary dilation5
paediatric patients5
classic kd5
nk cells5
centers required5
viral susceptibility5
children affected5
disease burden5
high viral5
less vigorous5
four seasonal5
cardiac markers5
shows milder5
multiple organ5
organ failure5
pulmonary disease5
major presentation5
hospital stay5
conical tube5
recent study5
acute infection5
severe systemic5
creatine kinase5
significant difference5
review board5
old girl5
supplemental table5
idiopathic arthritis5
retrospective review5
positive antibodies5
requiring intensive5
late april5
frequently reported5
cardiac function5
ct features5
peripheral blood5
myocardial injury5
aged years5
less commonly5
inflammatory state5
table summarizes5
testing positive5
severe sars5
age groups5
case definitions5
laboratory data5
england journal5
series multisystem5
hypothetical pathogenesis5
cardiac features5
develop mis5
extremity changes5
ground glass5
important lessons5
studies will5
medical care5
may provide5
response team5
lymphocyte ratio5
elevated cardiac5
high fever5
chinese center5
young age5
laboratory tests5
suspected covid5
previous reports5
oxygen saturation5
severe coronavirus5
young adult5
two investigators5
study period5
clinical findings5
distinct clinical5
study multisystem5
novel syndrome5
demographic data4
currently available4
myocardial depression4
city multisystem4
inflammatory cascade4
clinical picture4
much higher4
better understand4
parents guardians4
severely ill4
cell disease4
possible mis4
existing mis4
first reported4
children appear4
herd immunity4
pilot grant4
common symptoms4
shock related4
adaptive immune4
data integrity4
consider cytokine4
quality evidence4
illness requiring4
clinical data4
nasal cannula4
initial presentation4
infectious cytokine4
may lead4
reported data4
temporal association4
almost half4
immune globulin4
therapeutic anticoagulation4
children less4
studies included4
health emergency4
health status4
immune phenotypes4
similar findings4
incomplete kawasaki4
data analysis4
prospective cohort4
primary hlh4
multiorgan involvement4
patient received4
patient presenting4
virus spread4
alert network4
help healthcare4
pandemic continues4
disease associated4
present patients4
springer nature4
positive patients4
robust immune4
hospital protocols4
lower incidence4
immunomodulatory therapies4
prothrombotic coagulopathy4
commonly used4
adolescents multisystem4
family member4
manuscript writing4
hemodynamic instability4
stage iii4
data capture4
recently reported4
rheumatic diseases4
patient data4
severe adult4
patients presented4
symptom onset4
healthcare system4
pediatr doi4
patients present4
inflammatory emerging4
valvular dysfunction4
will allow4
prior infections4
higher rates4
innate response4
cutaneous manifestations4
induced multisystem4
verifying data4
several studies4
cardiac findings4
children infected4
journal pre4
high proportion4
affecting children4
immunoglobulin therapy4
associated pediatric4
imaging features4
ml conical4
funding agencies4
sickle cell4
developing mis4
novel covid4
laboratory studies4
standard deviations4
immunomodulatory effects4
petar rajkovic4
commonly reported4
typical covid4
pregnant women4
nasal gene4
emerging disease4
cellular injury4
milder disease4
elevated ferritin4
mycoplasma pneumoniae4
patients vs4
exponential growth4
presentation component4
newborns born4
children admitted4
see table4
many cases4
recovery trial4
adolescents temporally4
coronavirus pandemic4
six patients4
possibly due4
disease following4
temporally related4
pediatric viral4
new coronavirus4
like hyperinflammatory4
inflammatory process4
less common4
echocardiographic findings4
blood culture4
research staff4
skin rash4
like features4
angiotensin converting4
lymphocyte counts4
onset infection4
new syndrome4
type i4
neonatal early4
four weeks4
named multisystem4
less severity4
cardiovascular system4
infected mothers4
high incidence4
million confirmed4
current evidence4
approximately one4
team members4
covid phenotype4
respiratory viral4
old boy4
risk factor4
minimally invasive4
disease progression4
serology testing4
delayed development4
high dose4
research team4
childhood disease4
disease caused4
clinical care4
present cohort4
hyperimmune response4
renal function4
vessel vasculitis4
cardiac biomarkers4
tested positive4
uk tertiary4
cases reported4
open data4
thromboplastin time4
neuropsychiatric manifestations4
kd guidelines4
disease complicated4
reduced mortality4
one month4
mild symptoms4
early phase4
literature search4
health alert4
lymph node4
invasive mechanical4
protective immunity4
patients meeting4
pediatric infectious4
humoral responses4
rna polymerase4
signs symptoms4
moderate coronavirus4
open surgery4
conjunctival injection4
respiratory illness4
results show4
dermatologic manifestations4
may include4
become available4
critical illness4
partial thromboplastin4
dysregulated immune4
dexmedetomidine drip4
insufficient data4
creative commons4
alternative plausible4
like syndrome4
study covid4
liver injury4
elevated crp4
institutional study4
lower levels4
early reports4
states characteristics4
disease clinical4
median duration4
transcriptase polymerase4
positive children4
submitted work4
nasopharyngeal swab4
study clinical4
health service4
brain natriuretic4
three patients4
pediatric beds4
evidence suggests4
hospital course4
features similar4
test positive4
general population4
guidance statements4
term sequelae4
infected pneumonia4
virus disease4
infants born4
cracked lips4
fully understood4
national institutes4
information regarding4
older children3
cell entry3
ml aliquots3
classical kd3
abnormal laboratory3
neonatal exposure3
patients affected3
cases locally3
treat mis3
echocardiogram showed3
july th3
documented thrombosis3
sectional studies3
blood samples3
testing techniques3
initial laboratory3
acute disease3
categorical variables3
spectrum antibiotics3
different points3
plausible diagnosis3
highly elevated3
six days3
help identify3
altered inflammatory3
bilateral peripheral3
positive covid3
scientific evidence3
gadolinium enhancement3
hyperinflammatory response3
leukocyte antigen3
threatening manifestations3
neurological manifestations3
guidance document3
via telephone3
multiorgan dysfunction3
strong initial3
ecmo support3
pediatric cardiology3
jurisdictional claims3
host immune3
inflammatory diseases3
alarming rate3
human leukocyte3
mesenteric adenitis3
study id3
bacterial sepsis3
direct cellular3
mapping systemic3
tract disease3
cases described3
patient management3
high risk3
limited data3
antiviral therapy3
initial treatment3
multiple case3
paediatric hospital3
nonspecific inflammatory3
multiorgan failure3
immune cell3
th may3
center nis3
hospitalization rates3
imaging results3
specialist examinations3
china sars3
approximately half3
reactive antibodies3
shlh mas3
alanine aminotransferase3
acute early3
health system3
novel disease3
patients tested3
emergency departments3
institutional affiliations3
include direct3
bone marrow3
may benefit3
patients received3
reports emerged3
inflammatory agents3
intravenous immune3
big data3
vigorous immune3
clinical follow3
distancing measures3
reported mis3
clinical deterioration3
track covid3
prior infection3
mild illness3
chosen physicians3
staphylococcus aureus3
ml vs3
immunocompromised children3
better characterize3
household contacts3
us children3
inflammatory syndromes3
central role3
potential therapies3
state multisystem3
aged less3
medrxiv preprint3
large case3
also presented3
similar hyperinflammatory3
vasodilatory shock3
currently unknown3
four patients3
infection rates3
recent months3
resemble kawasaki3
states clinical3
prophylactic anticoagulation3
executive functioning3
care medicine3
multicenter studies3
paediatric population3
positive serology3
absolute lymphocyte3
clinical judgment3
emergency use3
morphologic patterns3
small percentage3
kdss patients3
disease covid3
lower prevalence3
chest radiograph3
stool samples3
massachusetts general3
aneurysm formation3
table i3
markedly elevated3
include fever3
close contact3
multidisciplinary team3
kd includes3
smart healthcare3
pediatric sars3
organ damage3
infected people3
available evidence3
future treatment3
mri images3
cord blood3
two entities3
will continue3
host response3
cardiac ventricular3
patient groups3
reserved table3
medical data3
highly increased3
picu admission3
china coronavirus3
tool published3
nan doi3
adjunctive therapy3
symptoms consistent3
fulminant myocarditis3
fold increase3
possible vertical3
study found3
common findings3
controlled trial3
sag motif3
children compared3
vaccination strategies3
antiviral therapies3
scientific brief3
nature remains3
bcg vaccination3
term follow3
pulmonary phase3
inflammatory conditions3
present results3
giant coronary3
hospitalized cohort3
clinical trial3
pcr negative3
either acute3
acid dehydrogenase3
complex immune3
may need3
immunomodulatory agents3
key words3
physical distancing3
managing mis3
patients diagnosed3
ferritin ng3
multisystem inflammation3
protocols included3
known entities3
corticosteroid treatment3
atrioventricular block3
ab profile3
least days3
milder symptoms3
provide insight3
significantly higher3
phase trial3
likely due3
requiring icu3
lactic acid3
organ injury3
stimulating factor3
city experience3
general hospital3
innate immunity3
published maps3
disease course3
worse outcomes3
cdc criteria3
old male3
disease mechanisms3
potentially infected3
standardized manner3
cardiac impairment3
adhesion molecule3
patients treated3
blood group3
laboratory evaluation3
children date3
often associated3
treated successfully3
vasopressor support3
pediatric rheumatology3
study provides3
underlying pathophysiology3
tertiary care3
chronic diseases3
pleural effusions3
regarding mis3
severe clinical3
lower gene3
children required3
right ventricular3
canonical kd3
serum inflammatory3
postinfectious multisystem3
pediatric multi3
block type3
will provide3
single centre3
th pandemic3
influenza pandemic3
art review3
another potential3
normal systolic3
clinical teams3
positive sera3
imaging characteristics3
school reopening3
clinical outcomes3
results suggest3
clinically severe3
compassionate use3
data become3
high prevalence3
children sars3
type iii3
emerging reports3
related inflammatory3
weeks prior3
neurological symptoms3
targeted therapies3
edta tube3
detailed descriptions3
respiratory virus3
shock requiring3
pcr positive3
relatively uncommon3
increasingly recognized3
delayed immunological3
become infected3
raised concern3
table compares3
invasive surgery3
patients required3
exact incidence3
collection cup3
theatre staff3
prevalence rate3
pericardial effusion3
tiered approach3
fat stranding3
psychiatric patients3
observational studies3
well established3
severe pneumonia3
humoral immune3
care medical3
healthier respiratory3
control clinic3
possible atypical3
review clinical3
treatment protocol3
viral pneumonia3
european countries3
quality biospecimens3
inflammatory biomarkers3
january st3
myocardial inflammation3
epidemiological features3
medical informatics3
neurological disorders3
prior exposure3
nih recommends3
high antibody3
ventricular ejection3
reported world3
kd findings3
care teams3
granulocyte colony3
kd shock3
active infection3
blood draws3
children multisystem3
room temperature3
related mis3
nasopharyngeal swabs3
kg intravenous3
mothers infected3
pediatric septic3
data collected3
antifungal therapy3
tertiary paediatric3
rare presentation3
procalcitonin level3
state department3
face shield3
also reported3
dermatol doi3
least two3
ards cases3
eligible patients3
questions remain3
recent reports3
dragan jankovic3
strawberry tongue3
serbia government3
nasal colonization3
termed multisystem3
cytokine levels3
patients included3
online version3
side effects3
response syndrome3
medical center3
statistical analyses3
remains undetermined3
profound acute3
il pg3
epidemiologic link3
coronary aneurysm3
working group3
obtain informed3
right lower3
medical condition3
kawasaki syndrome3
pandemic kawasaki3
tested negative3
prognostic value3
patients seen3
bsl safety3
questions relating3
suppression may3
phenotypes among3
tissue damage3
coronavirus pneumonia3
continuous variables3
following bsl3
treatment strategies3
care clinics3
disease development3
proposed mechanisms3
mis disease3
two independent3
findings included3
include acute3
continuous data3
middle east3
ethics approval3
intravenous immunoglobulins3
systemic hyper3
coronavirus diseases3
refractory kawasaki3
psychiatry team3
laboratory features3
infection among3
easysep direct3
dissecting kawasaki3
signaling pathways3
potentially lethal3
broader age3
european adhd3
cutaneous findings3
highly resilient3
current covid3
crp levels3
positive mothers3
health advisory3
commons licence3
colleagues found3
recent report3
may develop3
clinical approach3
york approach3
new cases3
pandemic pediatric3
published data3
frequently used3
multiracial male3
symptoms improved3
direct viral3
terminal pro3
mp igg3
illness onset3
develop severe3
step commands3
arthritis rheumatol3
studies may3
complete recovery3
severe inflammation3
search strategy3
hyperinflammatory condition3
initial diagnosis3
higher crp3
biospecimen collection3
sustained production3
including acute3
outcome data3
laboratory characteristics3
patients admitted3
imaging study3
covid pcr3
therapeutic strategies3
infection multisystem3
may represent3
pulmonary embolism3
angiotensinconverting enzyme3
abdominal ultrasound3
pediatric centers3
review date3
long term3
geographic region3
cotton balls3
remains neutral3
late gadolinium3
several case3
guidance provided3
cell activation3
five days3
typical chest3
series published3
bilateral ground3
hyperinflammatory process3
may serve3
children without3
will present3
ivig resistance3
weeks following3
suspected case3
rapidly emerging3
viral testing3
disease abnormalities3
infected mother3
rna extraction3
systemic juvenile3
western new3
two weeks3
may aid3
characteristics associated3
manifestations may3
helper cells3
brake activated3
east respiratory3
pandemic week3
airspace opacities3
pediatric emergency3
diagnosed children3
days following2
medical attention2
descriptive terminology2
adults sars2
vasoactive agents2
received immunomodulatory2
adult viral2
known whether2
cross protection2
elevated interleukin2
tract symptoms2
collecting high2
fewer outdoor2
adverse cardiac2
units clinical2
significantly reduced2
several reported2
perinatal aspects2
potential mechanisms2
typically experience2
complicating systemic2
wilcoxon rank2
prior research2
stroke nursing2
rapid prospective2
illness necessitating2
phenomenon caused2
preferred reporting2
epidemiologic characteristics2
clinical questions2
associated inflammatory2
data will2
igg positivity2
economic impacts2
abnormal echocardiogram2
scheduling module2
lr xr2
academic health2
italian epicenter2
class ii2
paediatric case2
typically characterized2
extremely elevated2
condition may2
centers including2
sick contacts2
preliminary evidence2
icu patients2
diagnosed cases2
multicentre trial2
ifn responses2
still scarce2
pcr tests2
learned regarding2
alternative diagnosis2
patients testing2
experienced less2
artery evaluation2
developed phase2
mild cases2
supplies required2
kawasakilike disease2
serbia open2
guidelines group2
world federation2
neutrophil rna2
dilatation compared2
artery changes2
table ii2
cognitive assessment2
pediatric sepsis2
major health2
buffered saline2
prolonged prothrombin2
blood urea2
disease transmission2
first dose2
demographic trends2
responder status2
lower viral2
us reported2
different countries2
children show2
blood processing2
infectious rather2
complications including2
emergency room2
delayed immune2
one recent2
olanzapine mg2
peripheral edema2
concurrent respiratory2
related multisystem2
human subjects2
positive serologic2
disease manifestations2
recent epidemiological2
chronic neurological2
myocardial fibrosis2
dimer levels2
epidemiologic evidence2
evolving nature2
completely novel2
cardiac chamber2
african americans2
children experienced2
others regarding2
likely represent2
well infant2
neurological diseases2
picu stay2
uk cohort2
demographic information2
lower hemoglobin2
disease recognition2
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