bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
mg kg	892
control group	751
intensive care	710
significantly higher	646
ng ml	600
blood pressure	569
septic shock	537
gene expression	506
mean age	480
present study	474
two groups	471
oxidative stress	425
significant difference	406
pg ml	403
statistically significant	402
amino acid	402
cell lines	391
risk factors	388
mechanical ventilation	380
care unit	379
critically ill	375
endothelial cells	369
cell line	361
insulin resistance	359
significant differences	358
amino acids	348
type diabetes	345
mg dl	337
metabolic syndrome	331
significantly increased	331
nitric oxide	328
blood flow	323
results suggest	318
blood samples	303
mrna expression	289
important role	288
body weight	281
ill patients	276
significantly lower	265
western blot	258
diabetes mellitus	258
peripheral blood	251
smooth muscle	248
years old	245
inflammatory response	242
significant increase	241
chronic hepatitis	240
organ failure	239
hbv dna	231
emergency department	229
significantly reduced	227
protein expression	227
plasma levels	225
logistic regression	223
cell proliferation	223
cardiac arrest	223
serum levels	221
cell death	221
intravenous immunoglobulin	219
specific ige	218
breast cancer	215
flow cytometry	211
cancer cells	209
growth factor	209
apache ii	205
risk factor	201
heart failure	200
critical care	198
immune response	197
adhesion molecules	197
statistical analysis	194
liver transplantation	192
university hospital	191
cardiac output	191
liver disease	190
side effects	189
heart rate	189
dependent manner	186
results indicate	185
increased risk	181
renal failure	181
icu patients	180
data suggest	180
performed using	178
pregnant women	174
mg ml	174
septic patients	173
one patient	172
dna damage	172
diabetic patients	172
patients undergoing	172
blood glucose	171
respiratory failure	170
ml kg	169
significantly decreased	169
patients admitted	169
cd cd	169
mrna levels	168
ml min	168
adipose tissue	166
body mass	165
myocardial infarction	164
high levels	162
epithelial cells	162
wild type	161
median age	160
cardiac surgery	158
health care	157
necrosis factor	157
molecular weight	157
significantly different	157
renal function	157
cell cycle	155
arterial pressure	155
prospective study	154
gestational age	154
determine whether	154
mass spectrometry	153
group i	152
immune system	152
bone marrow	152
time pcr	149
positive correlation	148
expression levels	148
regression analysis	147
arterial blood	146
study period	145
reactive oxygen	145
cell surface	145
patients treated	145
healthy controls	145
long term	145
significant decrease	144
patients without	143
tumor necrosis	143
lung injury	142
allergic rhinitis	142
severe sepsis	142
coronary artery	142
whole blood	141
multiple organ	141
medical center	139
may contribute	139
mass index	138
measured using	137
fatty acids	136
acute respiratory	136
nervous system	135
kg day	134
high risk	133
endothelial cell	133
hospital mortality	133
previous studies	133
mortality rate	132
higher levels	132
transcription factor	132
results show	132
significant reduction	132
glucose tolerance	131
cohort study	131
pulmonary artery	131
healthy volunteers	130
patients received	129
hepatocellular carcinoma	129
inflammatory cytokines	128
oxygen species	128
analysis revealed	128
protein levels	128
significant correlation	127
results showed	126
findings suggest	125
mechanically ventilated	125
may play	124
among patients	123
three groups	123
least one	122
copies ml	121
stem cells	121
mean arterial	121
cancer cell	121
first time	120
food allergy	120
significantly associated	120
respiratory distress	120
cell viability	119
blood loss	119
acute phase	119
tumor cells	119
two patients	118
uric acid	118
skin prick	117
study group	117
cell types	117
skeletal muscle	116
blot analysis	116
protein kinase	115
muscle cells	114
western blotting	114
clinical trials	114
observational study	112
vascular resistance	112
group ii	112
neopterin levels	112
binding protein	112
real time	111
within hours	111
icu stay	110
adult patients	110
trauma patients	110
left ventricular	110
two different	110
fat diet	109
reactive protein	109
central venous	109
waist circumference	108
pulmonary hypertension	107
informed consent	107
ii score	107
organ dysfunction	107
kg min	107
lg ml	107
molecular mechanisms	106
predictive value	106
analyzed using	106
weight loss	106
widely used	105
retrospective study	105
icu admission	105
patients receiving	104
ms ms	104
healthy subjects	103
cell adhesion	103
increased levels	102
extracellular matrix	101
plasma membrane	101
fatty acid	101
signal transduction	100
liver cirrhosis	100
venous blood	100
public health	100
determined using	100
glucose levels	100
animal models	100
transcription factors	100
spinal cord	99
may also	99
consecutive patients	99
commercially available	99
oxygen saturation	98
inhibitory effect	98
heart disease	98
data indicate	98
may lead	98
platelet count	97
customer service	97
increased significantly	97
mouse model	97
taken together	97
year old	96
distress syndrome	96
weight gain	96
normal range	96
deficient mice	96
ed patients	96
high dose	96
analysis showed	95
lipid peroxidation	95
cardiovascular disease	95
recent studies	94
hospital stay	93
multivariate analysis	93
treatment group	93
pediatric patients	92
commonly used	92
adverse effects	92
showed significant	92
time points	92
patients presenting	92
adhesion molecule	92
physical activity	91
type ii	91
fold increase	91
iu ml	91
inclusion criteria	91
emergency medicine	91
adverse events	91
type i	91
one year	91
case report	90
cardiovascular risk	90
grass pollen	89
protective effect	89
current study	89
cancer patients	89
cytokine production	89
odds ratio	89
three patients	89
platelet activation	89
first hours	88
also found	88
expression level	88
critical illness	88
wistar rats	88
survival rate	87
obese patients	87
platelet aggregation	87
increased expression	87
differentially expressed	87
per day	87
fold higher	87
high fat	86
plasma glucose	86
cell culture	86
mast cells	86
study included	85
patients showed	85
year period	85
central nervous	85
transgenic mice	85
insulin sensitivity	84
animal model	84
kidney injury	84
serum creatinine	84
dendritic cells	84
first trimester	84
total protein	84
atopic dermatitis	83
lipid profile	83
chain reaction	83
mononuclear cells	82
linear regression	82
significant changes	82
blood cells	82
ffas level	82
results demonstrate	82
ca i	82
previously reported	82
acute myocardial	82
brain injury	81
included patients	81
factors associated	81
activated protein	81
inflammatory responses	81
wide range	81
gel electrophoresis	81
clinical course	80
monoclonal antibodies	80
sectional study	80
statistical significance	80
signaling pathway	80
allergic patients	80
liver injury	79
ed visits	79
replacement therapy	79
nk cells	79
plasma concentrations	79
birth weight	79
study design	79
liver failure	79
blood gases	79
fetal growth	79
liver function	78
lung cancer	78
proinflammatory cytokines	78
dawley rats	78
wound healing	78
signaling pathways	78
polymerase chain	78
ang ii	78
elevated levels	77
may provide	77
portal vein	77
tidal volume	77
rheumatoid arthritis	77
house dust	77
control subjects	76
stem cell	76
five patients	76
mm hg	76
fatty liver	76
liver biopsy	76
control groups	75
negative correlation	75
high level	75
clinical practice	75
average age	75
age years	75
dose dependent	74
immune cells	74
serum albumin	74
protein synthesis	74
total cholesterol	74
family members	74
airway pressure	74
significantly elevated	74
respiratory tract	73
angiotensin ii	73
colorectal cancer	73
hydrogen peroxide	73
preliminary results	73
systolic blood	73
primary outcome	73
electron microscopy	73
prick tests	72
key role	72
protein level	72
immune responses	72
also observed	72
artery disease	72
pao fio	71
gas exchange	71
investigate whether	71
care units	71
three different	71
assessed using	70
ventilated patients	70
significant association	70
confidence interval	70
ct scan	70
prospective observational	70
viral load	70
acute pancreatitis	70
four patients	70
receptor antagonist	70
acute kidney	70
ob gyn	70
low levels	70
significant improvement	69
inflammatory diseases	69
pulmonary vascular	69
time course	69
cell cultures	69
plasma samples	69
fasting glucose	69
hemorrhagic shock	69
respiratory rate	68
monoclonal antibody	68
kidney disease	68
cardiac index	68
controlled trial	68
significantly correlated	68
well known	68
data show	68
positive patients	68
chest pain	68
cell activation	68
prick test	68
may result	68
inflammatory mediators	68
abdominal pain	67
lung function	67
ko mice	67
amniotic fluid	67
blood transfusion	67
sofa score	67
different types	67
university medical	67
vascular endothelial	67
hek cells	66
reperfusion injury	66
healthy individuals	66
binding site	66
cell growth	66
control animals	66
united kingdom	66
day mortality	66
decreased significantly	66
clinical data	65
mean values	65
patients died	65
within days	65
low dose	65
high affinity	65
rat model	65
low molecular	65
surgical patients	65
positively correlated	65
see table	64
systemic inflammatory	64
enzyme activity	64
th day	64
urinary tract	64
serum hbv	64
dust mite	64
acute renal	64
total number	64
oxide synthase	64
ex vivo	63
vascular smooth	63
binding sites	63
growth factors	63
evaluated using	63
positive cells	63
superoxide dismutase	63
even though	63
lymph nodes	63
nephrotic syndrome	63
pilot study	63
disease severity	63
pulmonary embolism	63
glucose metabolism	62
study aimed	62
ige levels	62
major role	62
medical students	62
one hour	62
tertiary care	62
study population	62
clinical trial	62
endothelial dysfunction	62
medical records	62
group compared	62
ejection fraction	61
six patients	61
mast cell	61
lower levels	61
biochemical parameters	61
ovarian cancer	61
total ige	61
hbv infection	61
folic acid	61
red blood	61
studies showed	61
patients underwent	61
patients suffering	61
month period	61
cardiac function	60
log copies	60
prostate cancer	60
investor sentiment	60
study showed	60
liquid chromatography	60
liver tissue	60
renal disease	60
serum samples	60
data demonstrate	60
total rna	60
one week	60
may help	59
severe asthma	59
cell type	59
umbilical vein	59
well tolerated	59
regression model	59
cord uid	59
randomized controlled	59
beneficial effects	59
bl mice	59
doc id	59
tumor cell	59
last years	59
treated patients	59
blood cell	59
treated cells	58
recent years	58
venous pressure	58
multiple sclerosis	58
treatment groups	58
coupled receptors	58
dna repair	58
plasminogen activator	58
age groups	58
lactate levels	58
factor viii	58
target genes	58
preterm birth	58
data analysis	58
density lipoprotein	57
high mortality	57
chronic liver	57
general population	57
new zealand	57
cortisol levels	57
background aims	57
bile acid	57
free radical	57
cell migration	57
higher risk	57
compared using	57
cardiovascular diseases	57
risk assessment	57
family history	57
type mice	57
first days	56
renal transplant	56
fasting blood	56
hcv rna	56
previously shown	56
may represent	56
right ventricular	56
three days	56
inflammatory markers	56
significantly improved	56
medical school	56
investigated whether	56
patient care	56
inflammatory cells	56
chronic disease	56
sample size	55
clinical studies	55
one hundred	55
epithelial cell	55
cytokine levels	55
culture medium	55
biological activity	55
two hours	55
critical role	55
descriptive statistics	55
healthy control	55
study shows	55
vital signs	54
cell count	54
old male	54
food intake	54
high concentrations	54
oxygen consumption	54
glycemic control	54
menstrual cycle	54
insulin levels	54
vitro studies	54
blood mononuclear	54
high prevalence	54
mg day	54
clinically relevant	54
membrane potential	54
standard deviation	54
tract infection	54
gold standard	54
crucial role	54
chb patients	54
kg bw	54
postoperative period	54
renal transplantation	54
transplant recipients	54
higher level	54
blood levels	53
heart surgery	53
data collection	53
time point	53
innate immune	53
hepg cells	53
four groups	53
preterm delivery	53
leading cause	53
demographic data	53
studies suggest	53
similar results	53
cd cells	53
trophoblast cells	53
significant change	52
groups according	52
lung tissue	52
bronchial asthma	52
hospital admission	52
also significantly	52
free radicals	52
way anova	52
dm patients	52
chart review	52
medical university	52
kg body	52
infected patients	52
times higher	52
head injury	52
allergic reactions	52
oral glucose	52
tissue factor	51
diabetic rats	51
prospective cohort	51
poorly understood	51
level i	51
different concentrations	51
clinical signs	51
tolerance test	51
patients may	51
may cause	51
causal closure	51
may explain	51
significantly greater	51
severe acute	51
genes involved	51
cirrhotic patients	51
clinical outcome	51
one month	51
escherichia coli	51
tissue damage	51
th cells	51
human umbilical	51
bile duct	50
energy expenditure	50
male wistar	50
staphylococcus aureus	50
eight patients	50
patients compared	50
patients aged	50
dna binding	50
pharmakologie und	50
levels increased	50
test results	50
dna levels	50
body temperature	50
copd patients	50
early diagnosis	50
group showed	50
chronic inflammation	50
function tests	50
response rate	50
alkaline phosphatase	50
host defense	50
two weeks	50
mrna level	50
exact test	50
bile acids	50
retrospective analysis	49
airway inflammation	49
insulin secretion	49
pivotal role	49
also showed	49
cytotoxic effects	49
mean value	49
dna methylation	49
diastolic blood	49
survival rates	49
knockout mice	49
ischemic stroke	49
fat mass	49
cells showed	49
clinical features	49
dose intravenous	49
toxic effects	49
tumor growth	49
ischemia reperfusion	48
acute lung	48
strand breaks	48
renal replacement	48
one case	48
time rt	48
remains unclear	48
parenteral nutrition	48
age group	48
recommendation iia	48
inflammatory process	48
und toxikologie	48
mean duration	48
results obtained	48
two cases	48
independent risk	48
receptor expression	48
growth restriction	48
seven patients	48
shock patients	48
venous thrombosis	48
connective tissue	48
retrospective cohort	48
future studies	47
chronic renal	47
low concentrations	47
tnf production	47
systemic vascular	47
preterm labor	47
promoter activity	47
white blood	47
pregnant rats	47
treated group	47
general hospital	47
heat shock	47
arachidonic acid	47
growth hormone	47
cell membrane	47
acid sequence	47
control study	47
body fat	47
placebo group	47
nuclear factor	47
blood gas	47
showed significantly	47
selectin expression	47
poor prognosis	47
hemodynamic parameters	47
type diabetic	47
serum alt	47
impaired glucose	47
cord blood	47
combination therapy	47
oxygen delivery	47
first step	47
per patient	47
elderly patients	47
disease progression	47
newly diagnosed	47
jugular vein	46
mechanisms underlying	46
cell survival	46
steady state	46
inhibitory effects	46
icu discharge	46
weeks gestation	46
remained unchanged	46
interquartile range	46
mortality rates	46
may affect	46
saps ii	46
two years	46
hours post	46
within minutes	46
much higher	46
different levels	46
tyrosine kinase	46
severe ards	46
protective effects	46
treated animals	46
significantly less	46
continuous infusion	46
human myometrium	46
binding proteins	46
bronchoalveolar lavage	46
beneficial effect	46
chronic inflammatory	46
spontaneous breathing	45
positive control	45
urine samples	45
hospital discharge	45
normal weight	45
confidence intervals	45
clinical chemistry	45
patients diagnosed	45
portal hypertension	45
time period	45
hours later	45
hbeag negative	45
culture media	45
coupled receptor	45
cardiopulmonary bypass	45
respiratory system	45
exclusion criteria	45
ml vs	45
large number	45
metabolic acidosis	45
thrombin generation	45
per year	45
molecular biology	45
apc resistance	44
pulmonary edema	44
differ significantly	44
also increased	44
central role	44
endotracheal tube	44
blood donors	44
carotid artery	44
also known	44
glucose level	44
cd expression	44
crp levels	44
closely related	44
intervention group	44
high incidence	44
genomic dna	44
well established	44
cerebrospinal fluid	43
cardiac hypertrophy	43
clinical symptoms	43
negative patients	43
higher mortality	43
prothrombin time	43
analysis using	43
red cell	43
information regarding	43
single nucleotide	43
patients developed	43
lipid metabolism	43
mean sd	43
blood cultures	43
acute coronary	43
cells treated	43
roc curve	43
free fatty	43
chronic kidney	43
umbilical cord	43
days post	43
cardiogenic shock	43
lung disease	42
randomly divided	42
negative predictive	42
energy metabolism	42
phase ii	42
less likely	42
surface expression	42
better understanding	42
high doses	42
control mice	42
comet assay	42
converting enzyme	42
treated mice	42
receptor activation	42
possible role	42
laboratory tests	42
children aged	42
hepatic failure	42
group iii	42
care medicine	42
blood vessels	42
enzyme activities	42
infectious diseases	42
postoperative day	42
serum level	42
immunoglobulin therapy	42
data showed	42
pulmonary disease	42
fetal membranes	42
allergic asthma	42
clinical characteristics	42
gram negative	42
cell function	42
enzymatic activity	42
congenital heart	42
ic values	41
pet rabbits	41
promoter region	41
independently associated	41
different time	41
quantum moves	41
receiver operating	41
transforming growth	41
normal human	41
success rate	41
antibiotic therapy	41
findings indicate	41
may indicate	41
urine output	41
potential role	41
decision making	41
colon cancer	41
apoptotic cells	41
vitro model	41
four different	41
significant positive	41
study demonstrates	41
circulating levels	41
therapeutic strategies	41
allergic diseases	41
serum concentrations	41
asthma control	41
inflammatory cytokine	41
pediatric intensive	41
several studies	41
mechanisms involved	41
lower level	41
recombinant protein	41
treated rats	40
internal medicine	40
group received	40
aged years	40
preliminary data	40
dna level	40
reference ranges	40
total body	40
randomly selected	40
acute liver	40
severity score	40
inflammatory processes	40
primary human	40
premature mortality	40
health problem	40
new therapeutic	40
clinical study	40
patients presented	40
small intestine	40
quantitative rt	40
national university	40
first week	40
control cells	40
tissue samples	40
blood volume	40
liver fibrosis	40
specific igg	40
early stage	40
teaching hospital	40
ed visit	40
mitochondrial membrane	40
patients requiring	40
primary care	40
scoring system	40
cesarean section	40
hcv infection	40
expression pattern	40
hbeag positive	40
frequently used	40
hbeag seroconversion	40
short term	40
mg protein	40
obese women	40
confocal microscopy	40
specific antibodies	40
mouse models	40
mental health	39
present work	39
degradation products	39
relative risk	39
three months	39
clinically significant	39
median time	39
surface area	39
blood sample	39
nursing staff	39
may influence	39
mean time	39
autoimmune diseases	39
plasma cortisol	39
ethics committee	39
significant effect	39
cells expressing	39
animal studies	39
statistical difference	39
single dose	39
pressure support	39
probably due	39
previous study	39
days later	39
multiple trauma	39
emergency physicians	38
head trauma	38
antioxidant status	38
fetal brain	38
kidney transplantation	38
six months	38
living cells	38
innate immunity	38
physical examination	38
ige level	38
three times	38
mcg kg	38
medical history	38
research institute	38
united states	38
obese subjects	38
normal saline	38
negative bacteria	38
injury severity	38
high degree	38
vein endothelial	38
previously described	38
increased mortality	38
brain death	38
cytotoxic effect	38
elevated serum	38
significant role	38
control rats	37
endoplasmic reticulum	37
drinking water	37
protein coupled	37
endotracheal intubation	37
positive results	37
may improve	37
square test	37
mammary gland	37
gastrointestinal tract	37
atrial fibrillation	37
among women	37
showed increased	37
trend towards	37
first day	37
human plasma	37
high serum	37
highly expressed	37
food allergies	37
tissue injury	37
important roles	37
therapeutic intervention	37
murine model	37
hcc patients	37
clinical significance	37
computed tomography	37
common cause	37
actin cytoskeleton	37
major cause	37
ards patients	37
flow rate	37
liver diseases	37
xanthine oxidase	37
tract infections	37
major surgery	37
nine patients	37
prognostic value	37
endothelial growth	37
overall mortality	37
low level	37
hospital cardiac	37
women undergoing	37
sepsis syndrome	37
ten patients	37
analysed using	37
related genes	37
university school	37
new york	37
flow cytometric	37
quantitative real	37
follicular fluid	37
clinical use	36
patient groups	36
normal values	36
marked increase	36
study investigated	36
calculated using	36
leptin levels	36
normal controls	36
organ damage	36
postmenopausal women	36
intracellular ca	36
human skin	36
skin tests	36
considered significant	36
white cell	36
hela cells	36
renal biopsy	36
alert level	36
tissue oxygenation	36
group consisted	36
serum il	36
also performed	36
nutritional support	36
food allergens	36
severe head	36
male rats	36
high ffas	36
higher concentrations	36
milk allergy	36
cervical ripening	36
small number	35
better understand	35
liver enzymes	35
high glucose	35
coagulation factors	35
retrospective review	35
provocation test	35
birch pollen	35
inhibitory activity	35
jugular bulb	35
female mice	35
significant increases	35
consecutive days	35
glomerular filtration	35
abdominal obesity	35
disease activity	35
showed higher	35
laboratory data	35
clinical outcomes	35
population exposure	35
mainly due	35
alertness level	35
early stages	35
levels may	35
environmental factors	35
broad spectrum	35
data collected	35
tumor suppressor	35
study aims	35
randomly assigned	35
important factor	35
class ii	35
studied patients	35
experimental model	35
high frequency	35
blood culture	35
collected data	35
data obtained	35
protective role	35
asthma symptoms	35
vein thrombosis	35
nadph oxidase	35
alt levels	35
morphological changes	34
stress response	34
first study	34
also measured	34
old female	34
overall survival	34
different doses	34
glasgow coma	34
hcc cell	34
years ago	34
transit disruptions	34
using elisa	34
matched controls	34
surgical procedures	34
platelet counts	34
complement activation	34
virus infection	34
immune function	34
linked immunosorbent	34
fio ratio	34
antioxidant capacity	34
map kinase	34
diagnostic criteria	34
high blood	34
significantly inhibited	34
acid residues	34
glucose uptake	34
graft survival	34
artery bypass	34
filtration rate	34
reporter gene	34
antioxidant activity	34
mesenchymal stem	34
hepatic fibrosis	34
study groups	34
drug resistance	34
ae years	34
higher rates	34
potential therapeutic	34
chronic diseases	34
first group	34
genes encoding	33
total serum	33
age range	33
statistically different	33
studies using	33
elisa kits	33
airway management	33
immunosorbent assay	33
burn injury	33
enteral nutrition	33
cell differentiation	33
blood coagulation	33
old woman	33
hdl cholesterol	33
correlation coefficient	33
may occur	33
beta cells	33
patients required	33
chronic hbv	33
granulosa cells	33
cytokine release	33
fasting plasma	33
takes place	33
tandem mass	33
study suggests	33
early pregnancy	33
operating characteristic	33
abdominal surgery	33
increasing concentrations	33
positive predictive	33
demographic characteristics	33
response syndrome	33
differential expression	33
kg i	33
glutathione peroxidase	33
human lung	33
model system	33
ad libitum	33
low density	33
selectin gene	33
dose response	33
kg hr	33
estrogen receptor	33
rat liver	33
pollen season	33
specific immunotherapy	33
acute rejection	33
mtt assay	33
cultured human	33
rat brain	33
bacterial infections	33
brain barrier	33
graft function	33
blood count	33
vascular endothelium	32
case reports	32
deep learning	32
following treatment	32
therapeutic effect	32
ed physicians	32
serum neopterin	32
nutritional status	32
bariatric surgery	32
wide variety	32
male patients	32
von willebrand	32
also investigated	32
arterial hypertension	32
may serve	32
receive either	32
stromal cells	32
expression profiles	32
inflammatory disease	32
alertness levels	32
igg levels	32
phase i	32
viral infection	32
septic complications	32
recommendation iib	32
cell membranes	32
fluorescence microscopy	32
secondary analysis	32
carcinoma cells	32
asthmatic patients	32
results support	32
will provide	32
two days	32
serum concentration	32
adrenergic receptor	32
apoptotic cell	32
conducted using	32
surgical icu	32
animal experiments	32
serum calcium	32
levels decreased	32
general anesthesia	32
renal allograft	32
soluble adhesion	32
mitochondrial dysfunction	32
laboratory parameters	32
gastric bypass	32
per se	32
regression models	32
provide evidence	32
ivig may	32
intravenous immunoglobulins	32
stage renal	32
oxidative damage	32
portal venous	32
artery catheter	32
mammalian cells	32
mice showed	32
chronic obstructive	32
controlled study	32
blood lactate	32
gene transcription	31
seven days	31
matrix metalloproteinases	31
recently shown	31
viral infections	31
thermal injury	31
correlated well	31
iga nephropathy	31
induced apoptosis	31
outcome measures	31
morbidly obese	31
blood sampling	31
inflammatory effects	31
study using	31
respiratory symptoms	31
plasma concentration	31
intercellular adhesion	31
per group	31
dna synthesis	31
increased blood	31
ill children	31
progenitor cells	31
evidence suggests	31
time dependent	31
trauma center	31
secondary outcomes	31
stroke volume	31
creatinine ratio	31
per week	31
study conducted	31
cells compared	31
renal tubular	31
every day	31
first year	31
therapeutic approaches	31
control patients	31
poor outcome	31
data suggests	31
chronic urticaria	31
induced dna	31
peanut allergy	31
host response	31
nmda receptor	31
observation period	31
mice lacking	31
complement system	31
mixed venous	31
effective treatment	31
model group	31
artery pressure	31
enteral feeding	31
fluid resuscitation	31
healthy children	31
virologic response	31
convenience sample	31
total antioxidant	30
prospectively studied	30
ventilatory support	30
body composition	30
orthotopic liver	30
surgery patients	30
glucose homeostasis	30
significant negative	30
relatively low	30
cardiovascular events	30
two types	30
alanine aminotransferase	30
community area	30
ion channels	30
asthma patients	30
level classification	30
human health	30
challenge test	30
highly significant	30
quantified using	30
novel therapeutic	30
cell carcinoma	30
disseminated intravascular	30
intravascular coagulation	30
acid composition	30
bleeding complications	30
early detection	30
may increase	30
polycystic ovary	30
natural killer	30
assess whether	30
quantitative analysis	30
play important	30
gene promoter	30
peritoneal macrophages	30
protein kinases	30
selectin levels	30
human endometrial	30
hyaluronic acid	30
sentiment index	30
mean serum	30
recombinant human	30
right ventricle	30
willebrand factor	30
inverse correlation	30
therapeutic agents	30
human keratinocytes	30
may reflect	30
repeated measures	30
also demonstrated	30
allergic reaction	30
allergic inflammation	30
results will	30
cholesterol levels	30
blood collection	30
femoral artery	30
oral administration	30
traumatic brain	30
rank test	30
increased serum	30
th percentile	30
lower respiratory	30
performance liquid	30
urinary protein	30
major risk	30
vivo studies	30
renal dysfunction	30
skin lesions	30
blood urea	30
emergency departments	30
adverse reactions	30
differential diagnosis	30
hepatic dysfunction	29
brain tissue	29
old boy	29
using specific	29
false positive	29
higher percentage	29
vascular tone	29
different cell	29
terminal domain	29
molecular level	29
retrospective chart	29
results demonstrated	29
normal pregnancy	29
fetal plasma	29
pcr analysis	29
risk patients	29
studies revealed	29
relatively high	29
fusion protein	29
might contribute	29
molecular mechanism	29
univariate analysis	29
edema formation	29
inflammatory reaction	29
dental disease	29
biological systems	29
statistically significantly	29
obstructive pulmonary	29
creatinine clearance	29
odds ratios	29
skin test	29
stimulating factor	29
multivariable logistic	29
receptor binding	29
maternal age	29
surgical treatment	29
dna adducts	29
hepatic arterial	29
written informed	29
decreased expression	29
also reduced	29
pseudomonas aeruginosa	29
liver cancer	29
respiratory syndrome	29
gestational diabetes	29
dependent increase	29
autoimmune disease	29
reduced expression	29
high sensitivity	29
wt mice	29
clotting time	29
neurodegenerative diseases	29
response element	29
blood products	29
world health	29
also studied	29
colon carcinoma	29
active site	29
higher incidence	29
following trauma	29
dependent protein	29
cell responses	29
second group	29
increased compared	29
signalling pathways	29
eoc cells	29
vena cava	29
also determined	29
serum leptin	29
contact dermatitis	29
tg mice	29
prospectively collected	29
naturally occurring	28
human placenta	28
i trauma	28
decidual cells	28
organ injury	28
treg cells	28
different groups	28
antithrombin iii	28
using different	28
human endometrium	28
old man	28
multivariate logistic	28
patients whose	28
samples obtained	28
also used	28
immune activation	28
four times	28
treatment period	28
nocturnal enuresis	28
cardiac fibroblasts	28
drug development	28
brain regions	28
whole genome	28
cell counts	28
emergency room	28
group patients	28
adverse effect	28
preventive behaviours	28
congestive heart	28
induced changes	28
renal insufficiency	28
coma scale	28
take place	28
liver damage	28
cerebral blood	28
time spent	28
social systems	28
baseline characteristics	28
binding activity	28
plasma leptin	28
human serum	28
inflammatory bowel	28
experimental animals	28
leydig cells	28
life support	28
affinity chromatography	28
i levels	28
sequence analysis	28
proinflammatory cytokine	28
ug ml	28
cell population	28
baseline values	28
chief complaint	28
underlying disease	28
treatment option	28
term follow	28
many patients	28
medical intensive	28
maternal plasma	28
took place	28
phosphorylation sites	28
secretory phase	28
using standard	27
mean difference	27
medical care	27
pulmonary function	27
sequence homology	27
significant higher	27
sepsis patients	27
new cases	27
strongly associated	27
recommendation i	27
classification network	27
cortisol production	27
situ hybridization	27
thromboplastin time	27
cells may	27
primary endpoint	27
per hour	27
ct scans	27
villous explants	27
bovine serum	27
immune cell	27
markedly increased	27
group without	27
patient group	27
patients using	27
peritoneal cavity	27
study provides	27
oxygen tension	27
ige binding	27
blood serum	27
alt normalization	27
past years	27
evaluate whether	27
polyclonal antibodies	27
peritoneal dialysis	27
obese children	27
soluble fibrin	27
lavage fluid	27
vascular permeability	27
investigated using	27
celiac disease	27
cancer stem	27
may reduce	27
drug administration	27
chemokine receptor	27
independent predictors	27
hepatic artery	27
increased il	27
pain management	27
metabolic control	27
immunohistochemical analysis	27
dna double	27
patient outcomes	27
low serum	27
diabetic subjects	27
blood transfusions	27
therapeutic hypothermia	27
kinase inhibitor	27
high density	27
leukocyte adhesion	27
stage i	27
positive blood	27
carbon dioxide	27
urea nitrogen	27
liver tissues	27
expressed genes	27
energy transfer	27
receptor potential	27
serum total	27
acid levels	27
survival time	27
bacterial translocation	27
natriuretic peptide	27
ovary syndrome	27
cellular processes	27
single cell	27
therapeutic approach	27
transient receptor	27
hiv infection	27
like growth	27
persistent pulmonary	27
mass spectrometer	27
inflammatory conditions	27
young adults	27
deep vein	27
steroid hormones	27
pathological conditions	27
intravenous administration	27
rats received	27
patient safety	27
bacterial infection	27
research center	27
blood sugar	27
care patients	27
clinical relevance	27
inotropic support	27
molecular mass	27
also evaluated	27
second messenger	27
cellular uptake	27
biologically active	27
lupus erythematosus	27
guinea pig	27
levels compared	27
plasma volume	27
still unknown	26
antiviral therapy	26
multiple logistic	26
identified using	26
postoperative complications	26
border restrictions	26
neurological outcome	26
low hdl	26
results indicated	26
table shows	26
clinical efficacy	26
ventricular function	26
serine protease	26
following parameters	26
fetal weight	26
severe respiratory	26
medical treatment	26
luciferase reporter	26
service level	26
serum ige	26
nitrogen balance	26
statistical differences	26
wilcoxon rank	26
correlation coefficients	26
nucleotide polymorphisms	26
patients following	26
months post	26
ae vs	26
significantly enhanced	26
laboratory findings	26
fasting insulin	26
higher rate	26
prone position	26
drug delivery	26
available elisa	26
done using	26
minute ventilation	26
adefovir dipivoxil	26
severity scores	26
fresh frozen	26
icu mortality	26
chronic pain	26
surface receptors	26
oxygen radicals	26
might play	26
expression analysis	26
pulmonary arterial	26
acid transport	26
low risk	26
neuronal cells	26
human liver	26
mean blood	26
studies will	26
essential role	26
largely unknown	26
shear stress	26
expression patterns	26
trpc channels	26
lymph node	26
sprague dawley	26
hydrocortisone therapy	26
experimental group	26
pain scores	26
adult respiratory	26
useful tool	26
highly sensitive	26
generalized anxiety	26
fetal sheep	26
remaining patients	26
admitted patients	26
facs analysis	26
studies show	26
coronary angiography	26
respiratory disease	26
increasing evidence	26
studies indicate	26
dendritic cell	26
cross sectional	25
platelet function	25
will also	25
nafld patients	25
decreased levels	25
hepatic function	25
angiotensin converting	25
viral hepatitis	25
asthmatic children	25
hemodynamic changes	25
test whether	25
differed significantly	25
two major	25
clinical decision	25
fold lower	25
using two	25
supine position	25
normal pregnancies	25
onset preeclampsia	25
change significantly	25
induced il	25
intrauterine growth	25
medical record	25
hepatic encephalopathy	25
emergency medical	25
healthy donors	25
cortisol concentrations	25
end stage	25
findings may	25
endothelial function	25
full length	25
enrolled patients	25
male sprague	25
cancer therapy	25
pregnancy outcome	25
target gene	25
proteins involved	25
human myometrial	25
protein content	25
mesangial cells	25
patient population	25
expression may	25
cell transformation	25
academic ed	25
four weeks	25
gene polymorphism	25
hours following	25
scanning electron	25
cerebral ischemia	25
hepatic blood	25
collagen type	25
oleic acid	25
directed mutagenesis	25
vitro assays	25
protein complexes	25
bowel disease	25
stably transfected	25
clinical history	25
paraffin embedded	25
colony formation	25
patient characteristics	25
therapeutic target	25
medical centre	25
will allow	25
clinical examination	25
myocardial ischemia	25
fetal lung	25
science foundation	25
clinical manifestations	25
studies demonstrated	25
guinea pigs	25
elisa method	25
different stages	25
pollen allergy	25
free amino	25
women without	25
intracranial pressure	25
show significant	25
cancer risk	25
white matter	25
levels within	25
mice compared	25
treatment response	25
good correlation	25
proteolytic activity	25
magnetic stimulation	25
without affecting	25
least two	25
normal control	25
factor vii	25
likert scale	25
ros production	25
also present	25
emergency care	25
mean sem	25
results revealed	25
multiple regression	25
like receptors	25
descriptive study	25
mda levels	25
receptor mrna	24
serum glucose	24
visceral fat	24
internal jugular	24
pg kg	24
activation markers	24
ml respectively	24
surgical procedure	24
clinical parameters	24
two main	24
patient satisfaction	24
inflammatory effect	24
obtained results	24
room temperature	24
cell infiltration	24
showed similar	24
nude mice	24
also shown	24
anhepatic stage	24
studied using	24
serum insulin	24
three years	24
whitney test	24
using flow	24
physiological conditions	24
apache iii	24
lactate dehydrogenase	24
eligible patients	24
severe trauma	24
trophoblast cell	24
bypass grafting	24
epidemiological studies	24
egg white	24
urinary neopterin	24
many studies	24
strong correlation	24
five years	24
human blood	24
systemic inflammation	24
transcriptional regulation	24
mean score	24
expression profile	24
insulin resistant	24
lps challenge	24
case series	24
stock market	24
vascular disease	24
lymphocyte ratio	24
positive effect	24
four days	24
drug allergy	24
transduction pathways	24
high grade	24
clinical improvement	24
cultured cells	24
factor alpha	24
underlying mechanisms	24
data provide	24
reverse transcription	24
thrombolytic therapy	24
total bilirubin	24
cells express	24
volatility index	24
using real	24
ige reactivity	24
human endothelial	24
expression vector	24
increasing doses	24
months later	24
signalling pathway	24
systemic lupus	24
placental tissue	24
programmed cell	24
curriculum development	24
higher doses	24
jak stat	24
undergoing elective	24
single center	24
pathway analysis	24
double strand	24
next step	24
first three	24
pediatric emergency	24
gene regulation	24
normal subjects	24
completely abolished	24
therapeutic potential	24
training program	24
tubular epithelial	24
endothelial activation	24
obstetrics gynecology	24
vitro experiments	24
within normal	24
two times	24
published data	24
health status	24
lesser extent	24
like receptor	24
data support	24
retinoic acid	24
normal alt	24
elective surgery	24
two studies	24
month follow	24
examined whether	24
therapeutic targets	24
inflammatory activity	24
medical college	24
monocytes macrophages	24
central obesity	24
late gestation	24
rats fed	24
resource utilization	24
correlation analysis	24
young children	24
miu ml	24
alternative splicing	24
class i	24
higher prevalence	24
independent predictor	24
inversely correlated	24
old girl	24
early phase	24
cells using	24
matrix proteins	24
study demonstrated	24
normal levels	24
alcoholic fatty	23
phase proteins	23
analysis indicated	23
cerebral oxygenation	23
cellular level	23
newborn offspring	23
fulminant hepatic	23
months old	23
antimicrobial activity	23
hazard ratio	23
organ system	23
female rats	23
ligand binding	23
present results	23
point mutation	23
kinase activity	23
underlying mechanism	23
body surface	23
health organization	23
elisa kit	23
intravenous injection	23
multiple linear	23
fluid balance	23
academic medical	23
one hand	23
capillary permeability	23
non invasive	23
ridesourcing demand	23
recent data	23
sum test	23
one group	23
well characterized	23
cell lysates	23
possible mechanism	23
epidermal growth	23
method using	23
selected patients	23
ace activity	23
every min	23
receptor agonist	23
increased plasma	23
adiponectin levels	23
within one	23
randomized study	23
right atrial	23
time periods	23
intracranial hypertension	23
soft tissue	23
model assessment	23
thrombus formation	23
aea levels	23
gnrh ii	23
health sciences	23
activator inhibitor	23
ca influx	23
triglyceride levels	23
every hours	23
immunoglobulin treatment	23
previous reports	23
polyacrylamide gel	23
recent study	23
neutrophil infiltration	23
low doses	23
controlled trials	23
parathyroid hormone	23
image analysis	23
i min	23
partial thromboplastin	23
metabolic disorders	23
open reading	23
study indicates	23
prognostic factors	23
results suggested	23
developmental stages	23
ng kg	23
ventricular ejection	23
patch test	23
chronic heart	23
markedly reduced	23
human neutrophils	23
immune globulin	23
bacterial growth	23
within months	23
adverse drug	23
venous catheter	23
cycle arrest	23
higher values	23
experimental conditions	23
respiratory insufficiency	23
hypertensive patients	23
herpes simplex	23
one third	23
research group	23
highly conserved	23
risk stratification	23
nan title	23
squamous cell	23
host cells	23
liver cells	23
cigarette smoke	23
target cells	23
previously demonstrated	23
successful treatment	23
concentration range	23
experimental models	23
negative sepsis	23
cerebral cortex	23
abdominal sepsis	23
classified according	23
also associated	23
obtained using	22
biological activities	22
camp levels	22
hours prior	22
diabetic mice	22
neuropathic pain	22
allele frequencies	22
caloric intake	22
mean pulmonary	22
induced activation	22
cgmp signaling	22
high expression	22
diagnostic accuracy	22
endotoxic shock	22
ic value	22
dust mites	22
less sensitive	22
bile ducts	22
infection control	22
cardiac failure	22
adult male	22
resistance index	22
lps injection	22
main cause	22
free cortisol	22
high resolution	22
adverse event	22
first two	22
cox regression	22
calcium levels	22
well understood	22
one day	22
extracorporeal circulation	22
treatment failure	22
patient demographics	22
preterm infants	22
induced cell	22
recently identified	22
last months	22
reported cases	22
fold increased	22
regarding covid	22
molecular basis	22
cecal ligation	22
median duration	22
considered statistically	22
resonance energy	22
study suggest	22
detected using	22
detection limit	22
early onset	22
inflammatory properties	22
laser desorption	22
uncontrolled asthma	22
hypersensitivity reactions	22
calcium channel	22
curve analysis	22
two methods	22
much lower	22
transcriptional level	22
tissue sections	22
vs control	22
reference range	22
clostridium difficile	22
study investigates	22
cell apoptosis	22
expressing cells	22
data regarding	22
coagulation system	22
international cases	22
receptor antagonists	22
levels correlated	22
histological examination	22
brain damage	22
lipoprotein cholesterol	22
bypass surgery	22
right heart	22
dna strand	22
significant impact	22
common sentiment	22
risk group	22
vitro study	22
membrane protein	22
cancer treatment	22
quality control	22
adverse outcomes	22
cytometric analysis	22
respiratory mechanics	22
well documented	22
inflammatory cell	22
life span	22
pressure monitoring	22
whole body	22
insulin signaling	22
days following	22
lactation period	22
diabetic nephropathy	22
inspiratory pressure	22
candidate genes	22
serum lactate	22
base excess	22
patient presented	22
mice fed	22
side effect	22
mean follow	22
new insights	22
experimental groups	22
mean ae	22
alt level	22
barrier function	22
complex i	22
cell damage	22
metabolic risk	22
rats treated	22
asthma exacerbation	22
protease inhibitors	22
using high	22
chi square	22
less pronounced	22
potent inhibitor	22
infectious disease	22
differentially regulated	22
cdna library	22
renal injury	22
experimental study	22
ischemic heart	22
statistical analyses	22
autologous blood	22
allergen immunotherapy	22
ischemic injury	22
fusion proteins	22
mcg ml	22
high pressure	21
uterine emg	21
tail vein	21
clinical laboratory	21
dependent inhibition	21
hospitalized patients	21
liver transplant	21
high performance	21
neonatal outcome	21
magnetic resonance	21
small molecules	21
infectious complications	21
found significantly	21
cationic amino	21
deleterious effects	21
despite enhanced	21
binding domain	21
pcr products	21
tidal volumes	21
silver nanoparticles	21
vitro methods	21
angiogenic factors	21
damage response	21
total cost	21
first episode	21
results provide	21
stimulating hormone	21
mass spectrometric	21
alcohol consumption	21
transit time	21
test system	21
rater reliability	21
additional information	21
coagulation factor	21
creatine kinase	21
organ donation	21
upper airway	21
higher serum	21
induced platelet	21
tree pollen	21
older age	21
medical sciences	21
term outcome	21
healthy women	21
tissue hypoxia	21
small cell	21
negatively correlated	21
reading frame	21
glucose concentration	21
nmol mg	21
showed high	21
northern blot	21
negative controls	21
shed blood	21
end products	21
increased incidence	21
might also	21
reduced glutathione	21
experiments revealed	21
pediatric nephrology	21
light microscopy	21
liver regeneration	21
specific expression	21
year follow	21
groups showed	21
serum protein	21
acid use	21
beta cell	21
long time	21
clinical diagnosis	21
induced oxidative	21
assay using	21
specific antibody	21
data sets	21
arrest patients	21
allograft recipients	21
new method	21
dna samples	21
also assessed	21
pcr amplification	21
acid metabolism	21
angiotensin system	21
received either	21
hoc analysis	21
using spss	21
patients included	21
psychological stress	21
injured patients	21
among children	21
pleural effusion	21
surgical intervention	21
age matched	21
five days	21
metabolic abnormalities	21
gas analysis	21
may therefore	21
negative control	21
transcript levels	21
cell populations	21
fully understood	21
prospective randomized	21
higher among	21
grade iii	21
tested whether	21
future research	21
continuous variables	21
melanoma cells	21
endothelial damage	21
lung compliance	21
mortality risk	21
surface antigen	21
induced liver	21
retrospectively reviewed	21
recently developed	21
positive rate	21
observations suggest	21
cardiac myocytes	21
advanced glycation	21
ml lps	21
coronavirus disease	21
remained stable	21
cerebral artery	21
least hours	21
calcium concentrations	21
pregnancies complicated	21
transcriptional activation	21
caesarean section	21
downward causation	21
many different	21
carbohydrate metabolism	21
supply chain	21
spontaneous circulation	21
pelvic organ	21
albumin levels	21
previously published	21
mean total	21
preliminary study	21
examine whether	21
granulosa cell	21
lps induced	21
acute inflammatory	21
findings show	21
intraperitoneal injection	21
frozen plasma	21
wedge pressure	21
animal testing	21
inos expression	21
hong kong	21
also decreased	21
nucleic acids	21
pcr using	20
term effects	20
platelet surface	20
cell mediated	20
tree nut	20
russian science	20
dimensional gel	20
one study	20
results may	20
treatment significantly	20
rank sum	20
treatment may	20
macrophage activation	20
large numbers	20
dependent variable	20
quality improvement	20
head ct	20
therapeutic strategy	20
human fetal	20
inferior vena	20
significant correlations	20
great importance	20
lipid peroxide	20
allele frequency	20
positively associated	20
new approach	20
serum cholesterol	20
leading causes	20
adult rats	20
open heart	20
late onset	20
patients suffered	20
ventricular fibrillation	20
two independent	20
physiological functions	20
also examined	20
kda protein	20
desorption ionization	20
joint inflammation	20
lung inflammation	20
apoptotic effects	20
mean body	20
attending physician	20
metabolic alterations	20
pancreatic beta	20
yrd region	20
adaptive immunity	20
significant risk	20
study will	20
plasma exchange	20
meconium passage	20
increasing number	20
glioma cells	20
without significant	20
left ventricle	20
opioid receptor	20
related changes	20
among others	20
higher compared	20
population health	20
cell signaling	20
induced increase	20
tumor tissue	20
health insurance	20
strong association	20
molecular dynamics	20
following surgery	20
one way	20
pulse oximetry	20
gene polymorphisms	20
systematic review	20
ca concentration	20
many cases	20
level ii	20
oxidized ldl	20
coagulation parameters	20
pediatric renal	20
oxygen extraction	20
china objective	20
outcome measure	20
paraffin sections	20
found significant	20
one patients	20
stress conditions	20
middle east	20
cardiopulmonary resuscitation	20
gastric cancer	20
tnf levels	20
differences among	20
catalytic activity	20
widely distributed	20
two months	20
los angeles	20
potential target	20
adult ed	20
human heart	20
analyses revealed	20
will help	20
meld score	20
mg daily	20
unclear whether	20
continuously monitored	20
laboratory rabbits	20
daily dose	20
independent variables	20
cell injury	20
lung diseases	20
free survival	20
human il	20
two children	20
mean number	20
severe allergic	20