trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
stem cell transplantation	1965
in patients with	1259
hematopoietic stem cell	1192
as well as	664
of the patients	615
of patients with	566
the use of	530
conflict of interest	526
of conflict of	480
disclosure of conflict	479
allogeneic hematopoietic stem	467
allogeneic stem cell	430
with a median	427
for patients with	408
the incidence of	398
the time of	396
a total of	395
stem cell transplant	391
the presence of	379
a median of	358
at the time	355
the treatment of	327
nothing to declare	316
the most common	315
the development of	311
is associated with	308
a median follow	308
there was no	304
bone marrow transplantation	300
in order to	299
the number of	293
peripheral blood stem	289
cumulative incidence of	284
the risk of	280
was associated with	273
versus host disease	269
graft versus host	267
at a median	260
associated with a	259
according to the	253
the role of	251
cd t cells	249
morbidity and mortality	247
the median age	243
the majority of	243
median age of	241
patients who received	238
in this study	237
study was to	233
of this study	232
autologous stem cell	231
median age was	227
due to the	226
the impact of	224
acute myeloid leukemia	220
hematopoietic cell transplantation	219
there were no	216
the aim of	211
one of the	211
years of age	210
was observed in	210
median time to	209
the outcome of	209
in patients who	208
were treated with	206
in all patients	200
to evaluate the	198
the diagnosis of	198
risk factors for	196
cd and cd	194
the median time	193
acute lymphoblastic leukemia	193
this study was	192
mg kg day	191
median age at	191
patients who underwent	188
in children with	187
of these patients	186
is a rare	184
stem cell source	183
after allogeneic hematopoietic	183
patients with a	182
reduced intensity conditioning	180
the conditioning regimen	177
the patient was	174
a patient with	174
in terms of	173
blood stem cell	171
median follow up	169
of patients who	168
all patients received	167
in the first	166
quality of life	165
for the treatment	165
the absence of	165
in addition to	164
there was a	161
respiratory syncytial virus	160
to determine the	160
age was years	157
all patients were	156
in of patients	155
increased risk of	154
of cd cells	154
aim of this	154
based on the	153
blood stem cells	153
haematopoietic stem cell	153
has not been	152
the patients with	152
total of patients	151
patients treated with	151
united states background	150
and chronic gvhd	150
acute and chronic	150
the age of	149
up of months	148
compared to the	148
in the setting	147
included in the	147
the setting of	147
were included in	147
by flow cytometry	146
as compared to	145
of acute gvhd	144
were associated with	144
the effect of	144
median number of	143
was found to	143
after a median	142
patients who had	141
median time of	140
bone marrow transplant	140
should be considered	137
patients in the	137
and in the	136
a history of	136
in combination with	136
of the disease	135
was defined as	134
the cumulative incidence	134
cell transplantation in	132
abstract case report	132
case report text	132
at time of	132
total body irradiation	131
found to have	131
in the treatment	131
found to be	130
follow up of	130
was diagnosed with	130
pediatric patients with	130
was treated with	129
age of years	127
in these patients	127
been shown to	126
cell transplant recipients	124
have been reported	124
patients with acute	124
in both groups	123
with or without	123
median of days	123
at least one	122
to assess the	122
of patients were	122
majority of patients	121
been associated with	121
in pediatric patients	121
cohort of patients	120
a median age	119
there is no	119
was used to	118
the efficacy of	118
of the study	117
in a patient	117
there is a	116
and overall survival	116
patients had a	115
are associated with	115
lung transplant recipients	115
in the absence	115
is the most	114
sickle cell disease	114
number of patients	113
year overall survival	113
has been reported	112
blood and marrow	112
allogeneic hematopoietic cell	112
conditioning regimen was	112
patients with high	112
disclosure of interest	111
risk factor for	110
lower respiratory tract	110
at our institution	110
was performed in	109
cells in the	109
the results of	109
the patients who	109
the most frequent	109
after allogeneic stem	108
the end of	108
patients who were	108
are needed to	107
in the study	107
was detected in	107
matched unrelated donor	107
a median time	106
the frequency of	106
in of the	106
in complete remission	106
be associated with	105
to be a	105
patients received a	105
whole exome sequencing	105
group of patients	104
none of the	104
bone marrow failure	104
the need for	103
who did not	103
umbilical cord blood	103
the importance of	102
after hematopoietic stem	102
associated with the	102
all patients had	101
was used in	101
of stem cells	100
and bone marrow	100
between january and	100
cell transplantation for	100
in hsct recipients	100
in the literature	99
as part of	99
is the first	99
has been shown	99
this is the	99
patients were treated	99
t cells and	98
during the first	98
of hematopoietic stem	98
incidence of relapse	97
hematopoietic stem cells	97
a diagnosis of	97
number of cd	96
shown to be	96
the first year	96
no significant difference	96
patients with aml	96
a case of	95
iv acute gvhd	95
out of patients	95
full donor chimerism	95
the rate of	94
months of age	94
mutations in the	94
the addition of	94
significant difference in	94
of chronic gvhd	93
we performed a	93
in multivariate analysis	93
in patients undergoing	93
the median follow	93
in case of	92
a cohort of	91
we report the	91
the management of	91
in peripheral blood	91
in our center	90
before and after	90
safety and efficacy	89
cause of death	89
we present a	89
was started on	89
a number of	89
retrospective chart review	89
adult patients with	89
patients are alive	89
and nk cells	89
the first days	88
in our cohort	88
chronic gvhd was	88
were diagnosed with	87
t cells were	87
neutrophil and platelet	87
to have a	87
and treatment of	86
analysis of the	86
the patients were	86
is characterized by	86
acute gvhd was	86
significantly associated with	86
for the first	86
occurred in patients	86
were used to	85
is one of	85
all patients with	85
median duration of	85
we report a	85
at the age	84
of children with	84
did not have	84
in the presence	83
been reported in	83
was significantly higher	83
when compared to	83
t cells in	83
a retrospective study	83
we aimed to	82
we retrospectively analyzed	82
associated with an	82
associated with increased	82
study is to	81
minimal residual disease	81
median time from	81
of the immune	81
the course of	81
the occurrence of	81
patients with hematological	80
to reduce the	80
p disclosure of	80
for all patients	80
part of the	80
it has been	79
in one patient	79
incidence of acute	79
overall survival was	79
well as the	79
no evidence of	79
no difference in	79
of t cells	79
observed in patients	79
the prevalence of	79
to investigate the	78
and efficacy of	78
dose of mg	78
died due to	78
in response to	78
severe combined immunodeficiency	78
for treatment of	78
respiratory tract infections	78
cd t cell	77
shown in table	77
and platelet engraftment	77
we conducted a	77
idiopathic pneumonia syndrome	77
chronic granulomatous disease	77
a dose of	77
case of a	77
patients with severe	77
the overall survival	77
analysis was performed	77
was seen in	76
of the patient	76
because of the	76
transplant related mortality	76
an increase in	76
significantly higher in	76
more likely to	76
in patients receiving	76
as a result	76
patients with hematologic	76
were observed in	75
in patients and	75
risk of relapse	75
a variety of	75
time to neutrophil	75
in all cases	74
compared to those	74
high risk of	74
a year old	74
central nervous system	74
with multiple myeloma	74
the case of	73
common variable immunodeficiency	73
data suggest that	73
myeloablative conditioning regimen	73
the study was	73
may be a	73
after stem cell	73
we found that	72
studies are needed	72
the only curative	72
the two groups	72
acute gvhd grade	72
in immunocompromised patients	72
the combination of	72
standard of care	72
no significant differences	72
an increased risk	72
the median number	72
at our center	72
did not receive	71
patients and methods	71
cd cells kg	71
of bone marrow	71
a combination of	71
of morbidity and	71
there are no	71
one patient with	71
after the first	71
this is a	71
of allogeneic hematopoietic	71
at high risk	71
the immune system	71
was diagnosed in	70
compared to patients	70
allogeneic bone marrow	70
in lung transplant	70
the proportion of	70
prophylaxis consisted of	70
at the end	70
and cd t	70
be considered in	70
was no significant	70
with hematologic malignancies	70
patients were transplanted	70
cord blood transplantation	70
all of them	70
the patient is	70
with a history	70
is important to	70
and mortality in	69
related to the	69
are shown in	69
in this patient	69
with hematological malignancies	69
t and b	69
acute graft versus	69
with and without	69
the bone marrow	69
of patients had	69
retrospective analysis of	69
at years of	69
of peripheral blood	69
in the group	69
higher risk of	69
was to evaluate	69
the control group	69
higher incidence of	68
to declare background	68
is the only	68
was achieved in	68
were found to	68
the start of	68
from diagnosis to	68
in our study	68
in pts with	68
to our knowledge	68
patients were included	68
a retrospective analysis	68
seems to be	67
one patient had	67
was no difference	67
the onset of	67
the outcomes of	67
higher in the	67
factors associated with	67
at years was	67
the lack of	67
autologous hematopoietic stem	66
between the two	66
in recipients of	66
with a high	66
causes of death	66
patients were in	66
extensive chronic gvhd	66
in a single	66
at a dose	66
of our patients	66
in hematopoietic stem	66
specific t cells	66
in the last	66
outcome of patients	66
with high risk	66
was found in	66
the context of	66
as gvhd prophylaxis	66
failure to thrive	65
due to a	65
within the first	65
to analyze the	65
age at diagnosis	65
patients with scd	65
the probability of	65
was the most	65
proportion of patients	65
mutation in the	65
the percentage of	65
months after hsct	65
disease status at	65
the most important	64
and the median	64
was used for	64
matched sibling donor	64
cd cd cd	64
and marrow transplantation	64
the safety and	64
median age years	64
prior to hsct	64
from january to	64
in our series	63
polymerase chain reaction	63
age at transplant	63
significant differences in	63
only one patient	63
among patients with	63
of all patients	63
a single center	63
the administration of	62
the type of	62
with respect to	62
for patients who	62
or chronic gvhd	62
can be used	62
after bone marrow	62
the purpose of	62
in the context	62
this retrospective study	62
used as a	62
and patients with	62
was present in	61
cause of morbidity	61
in the early	61
we describe a	61
was performed by	61
role in the	61
source of stem	61
and mycophenolate mofetil	61
was higher in	61
most of the	61
in this population	61
was used as	61
to compare the	61
and management of	61
was performed on	61
with acute leukemia	61
in children and	61
this study is	60
the united states	60
cd cell dose	60
was assessed by	60
acute or chronic	60
has been associated	60
patients with multiple	60
in comparison with	60
in this cohort	60
of stem cell	60
patients with primary	60
in the patients	60
and one patient	60
and the other	59
major cause of	59
associated with higher	59
resulted in a	59
s of s	59
old male with	59
the duration of	59
have not been	59
it is important	59
was performed with	59
the quality of	59
the incidence and	59
a result of	59
appears to be	59
patients diagnosed with	59
and severity of	59
further studies are	58
haploidentical stem cell	58
in those with	58
cell source was	58
is an effective	58
of nk cells	58
after allogeneic hsct	58
need to be	58
we hypothesized that	58
of the most	58
here we report	58
for the patients	58
patients with relapsed	58
the stem cell	58
the remaining patients	57
an important role	57
results suggest that	57
on the other	57
one patient died	57
age of the	57
matched related donor	57
of patients in	57
intensive care unit	57
for the development	57
the present study	57
respiratory viral infections	57
was performed using	57
performed a retrospective	57
can lead to	57
in bone marrow	57
days after hsct	57
are alive and	57
of the first	56
respiratory virus infections	56
followed by autologous	56
and safety of	56
for children with	56
depending on the	56
fludarabine mg m	56
included in this	56
the expression of	56
has been used	56
an unrelated donor	56
all the patients	56
could not be	55
of cd cd	55
been reported to	55
who received a	55
option for patients	55
the day of	55
no statistically significant	55
were performed in	55
were detected in	54
of the liver	54
between the groups	54
the patient had	54
in adult patients	54
we conclude that	54
we analyzed the	54
the effects of	54
have been described	54
progression free survival	54
at last follow	54
to patients with	54
in transplant recipients	54
donor t cells	54
for these patients	54
we evaluated the	54
disease free survival	54
males and females	54
used in the	54
acute gvhd and	54
were able to	54
the median duration	54
was significantly lower	54
absolute neutrophil count	54
patients who developed	54
we present the	54
a retrospective chart	54
with sickle cell	54
one patient developed	54
clinical and laboratory	54
and outcomes of	54
mg m day	53
a and b	53
to declare p	53
matched unrelated donors	53
who underwent hsct	53
high rate of	53
of patients and	53
patients with agvhd	53
allogeneic haematopoietic stem	53
to be associated	53
with an increased	53
and outcome of	53
we did not	53
not statistically significant	53
peripheral blood mononuclear	53
did not differ	53
memory b cells	53
on day and	53
gvhd prophylaxis was	53
from patients with	52
secondary graft failure	52
the patients had	52
we observed a	52
we investigated the	52
may lead to	52
to identify the	52
high dose chemotherapy	52
difference in the	52
patients undergoing allogeneic	52
at day and	52
aim of the	52
was referred to	52
in the majority	52
neutrophil engraftment was	52
cell transplantation is	52
and the patient	52
regimen consisted of	52
and stem cell	51
increase in the	51
bronchiolitis obliterans syndrome	51
hsct recipients with	51
the other hand	51
for gvhd prophylaxis	51
of t cell	51
during the study	51
cyclophosphamide mg kg	51
gvhd prophylaxis consisted	51
at months of	51
the severity of	51
of acute and	51
hematopoietic cell transplant	51
in the patient	51
who underwent allogeneic	51
a role in	51
the study period	51
safe and effective	51
the pathogenesis of	51
in this setting	50
from an hla	50
bone marrow and	50
memory t cells	50
up was months	50
is based on	50
with acute myeloid	50
bone marrow in	50
diffuse large b	50
unrelated cord blood	50
followed by a	50
the level of	50
resulting in a	50
upper respiratory tract	50
a prospective study	50
a group of	50
the last years	49
and peripheral blood	49
were transplanted in	49
time of diagnosis	49
inflammatory bowel disease	49
the objective of	49
diagnosis and treatment	49
blood mononuclear cells	49
t cells with	49
conditioning regimen consisted	49
who presented with	49
for at least	49
cd cells were	49
car t cells	49
been described in	49
donor lymphocyte infusion	49
in out of	49
important role in	49
the general population	49
in this group	49
treatment option for	49
in comparison to	49
were no significant	49
patients with pid	49
was well tolerated	49
with bone marrow	49
not associated with	49
incidence of grade	49
were the most	49
objective of this	48
the prevention of	48
are the most	48
os and pfs	48
t cell receptor	48
patients undergoing hsct	48
risk of developing	48
to describe the	48
conducted a retrospective	48
clinical trial registry	48
contribute to the	48
a risk factor	48
viral infections in	48
stem cell mobilization	48
chronic graft versus	48
of them were	48
were found in	48
were used for	48
from peripheral blood	48
virus infections in	48
high risk patients	48
is needed to	48
peripheral blood in	48
in univariate analysis	48
on day after	48
in the united	48
from unrelated donors	48
two patients with	47
to improve the	47
of the cases	47
patients who have	47
a reduced intensity	47
we sought to	47
results of the	47
x cd cells	47
respiratory tract infection	47
bone marrow biopsy	47
in the two	47
a decrease in	47
of the skin	47
marrow transplant recipients	47
patients with chronic	47
patients with mm	47
data on the	47
time from diagnosis	47
in the immunocompromised	47
the first time	47
national institute of	47
next generation sequencing	47
at transplant was	47
for blood and	47
the identification of	47
a matched unrelated	47
the fi rst	47
high levels of	47
reported in the	47
in patients after	47
in the pediatric	47
patients have been	47
the primary endpoint	46
in hsct patients	46
of grade ii	46
of cmv infection	46
melphalan mg m	46
involved in the	46
of our study	46
patients with refractory	46
and cd cells	46
patients who did	46
all patients who	46
chronic gvhd and	46
not significantly different	46
prior to the	46
in patients treated	46
of pediatric patients	46
and in patients	46
be considered as	46
and may be	46
of the conditioning	46
in two patients	46
in a cohort	46
is a common	46
t cell depletion	46
conditioning regimen and	46
of mg kg	46
respiratory tract disease	46
chart review of	46
was carried out	46
primary graft failure	46
the peripheral blood	46
follow up was	46
in the control	45
of patients was	45
signs and symptoms	45
combined immune deficiency	45
all of the	45
year os was	45
overall survival and	45
at a single	45
impact on the	45
and months after	45
patient is a	45
patients with cancer	45
intensity conditioning regimen	45
purpose of this	45
the possibility of	45
two patients had	45
all patients engrafted	45
high incidence of	45
among the patients	45
differences in the	45
sinusoidal obstruction syndrome	45
is an important	45
report text introduction	45
stem cell transplants	45
and cord blood	45
little is known	44
medical records of	44
patients had received	44
of patients undergoing	44
national institutes of	44
platelet engraftment was	44
showed that the	44
invasive fungal infections	44
patients did not	44
institutes of health	44
history of recurrent	44
up to of	44
a significant increase	44
at the university	44
is caused by	44
conditioning regimen for	44
the degree of	44
increased risk for	44
engraftment was days	44
compared with the	44
of patients received	44
the analysis of	44
of cmv reactivation	44
in cases of	44
conditioning regimens were	43
patients who are	43
age at hsct	43
caused by mutations	43
with a higher	43
in association with	43
the first months	43
time of transplant	43
patients with an	43
and b cell	43
and risk factors	43
has been described	43
a reduction in	43
the cause of	43
red blood cell	43
in our institution	43
were no differences	43
it is not	43
of overall survival	43
of death were	43
is a major	43
statistically significant difference	43
patients suffering from	43
in of cases	43
to be the	42
was complicated by	42
at the same	42
in the hsct	42
the same time	42
the group of	42
after hsct and	42
to determine if	42
defined as the	42
of them had	42
we retrospectively reviewed	42
of age with	42
overall survival of	42
was peripheral blood	42
year cumulative incidence	42
performed in patients	42
the detection of	42
patients were diagnosed	42
is safe and	42
was to assess	42
risk factors and	42
related or unrelated	42
from a matched	42
b cells and	42
old female with	42
significant increase in	42
on days and	41
patients with advanced	41
the risk factors	41
in the development	41
and should be	41
stem cells in	41
adverse events were	41
of graft failure	41
were used in	41
significantly lower in	41
development of a	41
compared to healthy	41
in patients without	41
increased susceptibility to	41
in contrast to	41
primary immune deficiency	41
overall survival in	41
of the graft	41
relapsed or refractory	41
a trend towards	41
and marrow transplant	41
seen in patients	41
in the general	41
patient with a	41
from healthy donors	41
treatment related mortality	41
and of patients	41
likely to be	40
in our experience	40
clinical features of	40
aim was to	40
donor lymphocyte infusions	40
one or more	40
hsct in our	40
severe chronic gvhd	40
there have been	40
allogeneic hsct recipients	40
review of the	40
donor and recipient	40
in a large	40
by mutations in	40
with high dose	40
transplantation in patients	40
prior to transplant	40
of a patient	40
to be effective	40
to the development	40
the dose of	40
autologous peripheral blood	40
the patient with	40
patients with cgd	40
with a mean	40
efficacy and safety	40
may contribute to	40
is known about	40
regulatory t cells	40
have been associated	40
successfully treated with	40
the association between	40
in our patient	40
of the ebmt	40
were enrolled in	40
and t cell	40
a bone marrow	40
stem cells from	40
the potential to	40
from the same	40
infections in patients	40
time of the	40
mesenchymal stem cells	40
to determine whether	40
the source of	40
we found a	40
of gvhd and	40
no differences in	40
a subset of	40
family history of	40
more than one	40
who underwent allo	40
response to treatment	39
chronic gvhd were	39
be effective in	39
has also been	39
at months after	39
end of the	39
here we present	39
in recent years	39
found in the	39
total number of	39
findings suggest that	39
severe aplastic anemia	39
play a role	39
in multiple myeloma	39
of pts with	39
a matched sibling	39
of cd t	39
the patients was	39
gvhd grade ii	39
of the clinical	39
have been shown	39
cd cd ra	39
were more likely	39
complete donor chimerism	39
children and adolescents	39
expression of cd	39
the patients received	39
the fact that	39
suggest that the	39
risk of gvhd	39
in the second	39
to of patients	39
days after transplantation	39
at risk of	39
patients transplanted from	39
and duration of	39
may not be	39
were used as	39
was admitted to	39
for the prevention	38
the basis of	38
patient had a	38
in allogeneic stem	38
be due to	38
were transplanted from	38
half of the	38
main cause of	38
retrospective review of	38
in the other	38
developed acute gvhd	38
with history of	38
was not statistically	38
immunoglobulin replacement therapy	38
mg kg d	38
these patients were	38
associated with high	38
understanding of the	38
and b cells	38
overall response rate	38
no signs of	38
red blood cells	38
to study the	38
solid organ transplant	38
patients were enrolled	38
is a well	38
known to be	38
of cd and	38
and number of	38
be used to	38
in this case	38
of invasive fungal	38
a major cause	38
he was diagnosed	38
used in patients	38
cd cells in	38
differences between the	38
stem cells were	38
at risk for	38
cd cell count	38
invasive fungal infection	38
interstitial lung disease	37
in the present	37
were identified in	37
year old male	37
of death in	37
out of the	37
we report on	37
and has been	37
acute myeloid leukaemia	37
of allogeneic hsct	37
on the outcome	37
was reported in	37
moderate to severe	37
and did not	37
the influence of	37
over the last	37
on the use	37
likely to have	37
needs to be	37
this study we	37
results of a	37
we report our	37
children with scd	37
have been used	37
patients at risk	37
higher in patients	37
was identified in	37
autologous and allogeneic	37
of which were	37
in the non	37
and of the	37
significant difference between	37
and for the	37
were classified as	37
approved by the	37
on day of	37
presence of a	37
to be an	37
the association of	37
hsct in patients	37
patients died of	36
in patients at	36
of allogeneic stem	36
conflicts of interest	36
and autologous stem	36
and can be	36
at increased risk	36
were collected from	36
the relationship between	36
and quality of	36
the beginning of	36
the main cause	36
t cells from	36
a higher risk	36
was performed to	36
white blood cell	36
the patient and	36
related mortality was	36
of primary immunodeficiency	36
the era of	36
for hematologic malignancies	36
observed in the	36
the introduction of	36
a significantly higher	36
only curative treatment	36
reported to be	36
may have a	36
of infectious complications	36
chemotherapy followed by	36
patients with all	36
with primary immunodeficiency	36
high risk for	36
according to our	36
treatment for patients	36
were in cr	36
switched memory b	36
who had a	36
was based on	35
a statistically significant	35
occurred in of	35
therapy in patients	35
significant differences between	35
and disease free	35
was consistent with	35
age of patients	35
a matched related	35
the patients in	35
is feasible and	35
have shown that	35
a myeloablative conditioning	35
event free survival	35
more common in	35
the first case	35
recurrent sinopulmonary infections	35
he was treated	35
group and in	35
in the era	35
mg kg and	35
and chronic graft	35
single center experience	35
mobilized peripheral blood	35
transplanted in cr	35
was the only	35
in patients transplanted	35
who had received	35
respiratory distress syndrome	35
one of them	35
treated with a	35
cell transplantation with	35
with the same	35
significant impact on	35
the infectious diseases	35
low incidence of	35
developed chronic gvhd	35
did not show	35
patients with mds	35
of the cd	35
expression of the	35
at this time	35
have been identified	35
for more than	35
chronic myeloid leukemia	35
the entire cohort	35
patient was diagnosed	35
were conditioned with	35
may be an	35
tumor necrosis factor	35
we describe the	34
at diagnosis was	34
other respiratory viruses	34
than in the	34
compared to controls	34
incidence of chronic	34
of acute graft	34
did not respond	34
outcomes of patients	34
the mean age	34
conditioning regimen with	34
patients transplanted with	34
present a case	34
of the pts	34
in the same	34
such as the	34
data were collected	34
mg kg on	34
with acute gvhd	34
detected in the	34
was bone marrow	34
no difference between	34
months after transplantation	34
igg mg dl	34
with acute lymphoblastic	34
remains to be	34
to that of	34
were obtained from	34
chronic gvhd in	34
in the multivariate	34
the efficacy and	34
ikbkb immune deficiency	34
abstract already published	34
with newly diagnosed	34
for high risk	34
with a low	34
colony stimulating factor	34
could be a	34
transplant recipients with	34
in this retrospective	34
first complete remission	34
in a multivariate	34
free survival was	34
a primary immunodeficiency	34
the other patients	34
in neutropenic patients	34
our data suggest	34
following hematopoietic stem	34
of consecutive patients	34
had to be	34
more than of	34
with regard to	34
the spectrum of	34
was not associated	34
patients in cr	34
we compared the	34
changes in the	34
a series of	34
b and nk	34
time of days	34
to understand the	34
at that time	33
age at transplantation	33
were reported in	33
and lack of	33
and infectious diseases	33
diffuse alveolar hemorrhage	33
were in complete	33
and young adults	33
patients with the	33
report text background	33
acute respiratory distress	33
school of medicine	33
high rates of	33
at mg kg	33
in vitro and	33
the median of	33
were divided into	33
summarized in table	33
patients affected by	33
any of the	33
survival in patients	33
kg cd cells	33
of b cells	33
time of transplantation	33
and fungal infections	33
up to years	33
ranging from to	33
to the hospital	33
patients with non	33
who had undergone	33
incidence of agvhd	33
was able to	33
in the future	33
were significantly higher	33
cytokine release syndrome	33
cell dose was	33
referred to our	33
on the basis	33
majority of the	33
significant morbidity and	33
nk cells were	33
independently associated with	33
a child with	33
autoimmune hemolytic anemia	33
engraftment was achieved	33
and response to	33
report a case	33
the evaluation of	33
curative treatment for	33
of relapse was	33
study of the	33
or unrelated donor	32
donor chimerism and	32
and hematopoietic stem	32
enrolled in the	32
a significant difference	32
median dose of	32
overall survival at	32
considered to be	32
patients with sickle	32
cd cd t	32
the multivariate analysis	32
on the day	32
a retrospective review	32
in the pathogenesis	32
we observed that	32
do not have	32
received myeloablative conditioning	32
in adults with	32
to neutrophil engraftment	32
one patient who	32
for the entire	32
found in patients	32
with a lower	32
and months post	32
is to evaluate	32
evaluation of the	32
for a median	32
reduction in the	32
with median age	32
was determined by	32
all but one	32
treatment of patients	32
graft failure was	32
small number of	32
pediatric hematology oncology	32
will be presented	32
of allergy and	32
early diagnosis and	32
was significantly associated	32
the goal of	32
of the following	32
no impact on	32
organ transplant recipients	32
t cell lymphopenia	32
of relapse and	32
of the two	32
in our centre	32
were identified as	32
was evaluated by	32
is known to	32
to increase the	32
and cd cd	32
we aim to	32
of them received	31
for acute myeloid	31
between patients with	31
solid organ transplantation	31
and use of	31
with the use	31
treated with high	31
may be considered	31
patients from the	31
allogeneic hsct in	31
january and december	31
an average of	31
with the development	31
pfs and os	31
no conflict of	31
in accordance with	31
risk factors of	31
consecutive patients with	31
was confirmed by	31
retrospective study of	31
increase the risk	31
similar in both	31
was negative for	31
the infusion of	31
bone marrow was	31
can be considered	31
os and dfs	31
had at least	31
in mm patients	31
analyses were performed	31
pediatric oncology patients	31
months after transplant	31
months after the	31
the clinical and	31
diagnosis and management	31
our cohort of	31
b cell lymphoma	31
well tolerated and	31
samples were collected	31
in high risk	31
and the presence	31
were excluded from	31
with at least	31
gvhd occurred in	31
is a potentially	31
was a significant	31
and the use	31
were defined as	31
infection in the	31
cd cells was	31
at hsct was	31
percent of patients	31
peripheral blood and	31
d and d	31
a multivariate analysis	31
correlated with the	31
was not significantly	31
year after hsct	31
graft failure and	31
and type of	31
of patients treated	31
used for the	31
of patients are	31
characteristics of the	31
in vivo t	31
on behalf of	31
gvhd was observed	31
acute chest syndrome	31
and nk cell	31
those who did	31
a safe and	31
mean age of	31
working party of	31
of respiratory syncytial	31
of the donor	31
this patient population	31
with relapsed refractory	31
patients with haematological	30
the underlying disease	30
children and adults	30
mg m for	30
patients transplanted in	30
and treated with	30
evaluate the impact	30
there has been	30
in the diagnosis	30
at least months	30
an effective treatment	30
the oral cavity	30
we hypothesize that	30
conditioning regimen in	30
are known to	30
median time between	30
first days after	30
or in combination	30
our study was	30
from an unrelated	30
two of them	30
was given to	30
was myeloablative in	30
alive and well	30
studies have shown	30
less than years	30
in the number	30
in the high	30
was in the	30
mg m on	30
time of hsct	30
and platelet recovery	30
the amount of	30
a mutation in	30
should be performed	30
up of days	30
and of them	30
is a curative	30
was a trend	30
of patients receiving	30
hla identical sibling	30
was to analyze	30
infection in patients	30
upper and lower	30
cd cells from	30
two of the	30
reduce the risk	30
iga and igm	30
the ability to	30
in partial remission	30
had a significantly	30
the mechanism of	30
time to platelet	30
party of the	30
appear to be	30
proved to be	30
complication of allogeneic	30
virus infection in	30
was to determine	30
consistent with the	30
was similar in	30
presented with a	30
the feasibility of	30
reported in patients	30
to define the	30
cell transplantation from	30
to neutrophil and	30
dose chemotherapy and	30
to examine the	30
the date of	30
primary immunodeficiency diseases	30
a poor prognosis	30
day and day	30
results in a	30
from bone marrow	30
described in the	30
there were patients	30
in allogeneic hematopoietic	30
t cell depleted	29
we developed a	29
and is associated	29
in the past	29
were not significantly	29
thought to be	29
for the management	29
t cell proliferation	29
of patients at	29
be an effective	29
hsct from a	29
area under the	29
syncytial virus infection	29
in some cases	29
present in the	29
mean age at	29
samples from patients	29
test was used	29
use of a	29
of the european	29
infections in hematopoietic	29
impact of the	29
year os and	29
an autosomal recessive	29
due to its	29
the rest of	29
in the post	29
play an important	29
is not well	29
on day was	29
stem cells transplantation	29
patient was treated	29
subset of patients	29
with r r	29
of at least	29
are summarized in	29
and patients were	29
be related to	29
a significant reduction	29
two patients were	29
lead to a	29
disorder characterized by	29
is a frequent	29
status of the	29
efficacy of the	29
these data suggest	29
in allogeneic hsct	29
one patient was	29
a trend for	29
and had a	29
incidence and severity	29
b and t	29
noninfectious pulmonary complications	29
in the management	29
is a primary	29
has to be	29
the patient developed	29
recurrent infections and	29
we were able	29
the ability of	29
or bone marrow	29
of donor t	29
chart review was	29
leading cause of	29
detected in patients	29
were transplanted with	29
three patients with	29
were compared to	29
regimen was myeloablative	29
x kg cd	28
specific cd t	28
lower in the	28
in first complete	28
be considered for	28
in the cd	28
loss of function	28
course of the	28
and total body	28
led to a	28
to those of	28
of cvid patients	28
in solid organ	28
with the exception	28
this was a	28
these patients are	28
was approved by	28
occurred in the	28
univariate and multivariate	28
prospective studies are	28
with increased risk	28
at the last	28
acute kidney injury	28
received a myeloablative	28
the most frequently	28
seem to be	28
absolute lymphocyte count	28
in the blood	28
at transplantation was	28
at the start	28
and grade iii	28
between and were	28
a lack of	28
in hematopoietic cell	28
with a diagnosis	28
curative option for	28
it can be	28
in group a	28
groups of patients	28
addition to the	28
analysis showed that	28
when compared with	28
in the case	28
a high risk	28
infections in the	28
in one case	28
and mortality after	28
the most commonly	28
associated with better	28
of sos vod	28
mg m d	28
at the moment	28
that patients with	28
were analyzed by	28
length of stay	28
is a significant	28
this group of	28
received an allogeneic	28
the donor was	28
incidence of cmv	28
identical sibling donor	28
median overall survival	28
of hsct recipients	28
of adult patients	28
associated with poor	28
the study is	28
between and at	28
blood samples were	28
a stem cell	28
treatment of acute	28
or unrelated donors	28
chemotherapy and autologous	28
patients who died	28
in the peripheral	28
considered as a	28
were compared with	28
a high rate	28
seen in the	28
may result in	28
median cd cell	28
be used as	28
from matched unrelated	28
patients receiving a	28
median time for	28
patients were alive	28
associated with improved	28
were similar in	28
large b cell	28
liposomal amphotericin b	28
significant decrease in	28
she was started	28
t cell development	28
and at years	28
cells and cd	28
and the development	28
consecutive patients who	28
a significant decrease	28
was significant for	28
as stem cell	28
large cohort of	27
all patients in	27
older than years	27
and a median	27
serve as a	27
neutropenic patients with	27
pts received a	27
for pts with	27
poor graft function	27
as a treatment	27
be able to	27
especially in the	27
showed a significant	27
not respond to	27
associated with lower	27
recipients of allogeneic	27
nk cells in	27
survival at years	27
we retrospectively evaluated	27
higher rate of	27
peripheral blood was	27
gvhd of the	27
patient presented with	27
were performed at	27
herpes simplex virus	27
results indicate that	27
achieved complete remission	27
was notable for	27
the current study	27
successful treatment of	27
a mean of	27
cell receptor excision	27
for patients in	27
children with cancer	27
continued to have	27
as a consequence	27
was started at	27
was due to	27
these patients had	27
associated with significant	27
chimeric antigen receptor	27
male and female	27
these results suggest	27
study was conducted	27
the prognosis of	27
data show that	27
incidence of gvhd	27
for diagnosis and	27
of uncertain significance	27
for the diagnosis	27
the second patient	27
and in vivo	27
significantly higher than	27
should be used	27
has the potential	27
associated with severe	27
t cell counts	27
performed in the	27
were isolated from	27
first year of	27
alloreactive t cells	27
university medical center	27
source was peripheral	27
a second transplant	27
after hsct in	27
is a severe	27
multiple myeloma patients	27
allogeneic hsct for	27
received peripheral blood	27
of the same	27
led to the	27
cell transplantation recipients	27
mean number of	27
stem cell collection	27
and patients had	27
more frequent in	27
with chronic gvhd	27
difference between the	27
as the first	27
based gvhd prophylaxis	27
who received hsct	27
to be safe	27
allergy and infectious	27
patient was started	27
noted to have	27
the result of	27
identified in the	27
hsct in the	27
an attempt to	27
who do not	27
stem cell infusion	27
a consequence of	27
the availability of	27
institute of allergy	27
patient died of	27
the last follow	27
of treatment with	27
of unknown significance	27
in a significant	27
fungal infections in	27
significant reduction of	27
mean age was	27
therapy in the	27
is a life	27
after initiation of	27
low levels of	27
b cells were	27
a period of	26
have also been	26
patients were followed	26
as high as	26
the group with	26
and myelodysplastic syndrome	26
patients with low	26
the characteristics of	26
of febrile neutropenia	26
of choice for	26
for the whole	26
increased incidence of	26
to describe a	26
and at the	26
cd ra cd	26
that can be	26
we report here	26
in the course	26
report our experience	26
patients were identified	26
was to compare	26
in our patients	26
after the second	26
due to disease	26
in relation to	26
of this retrospective	26
she was diagnosed	26
in the bone	26
days after the	26
in the transplant	26
is thought to	26
primary endpoint was	26
the response to	26
no cases of	26
following allogeneic hematopoietic	26
one year after	26
with a reduced	26
matched sibling donors	26
and cd cell	26
mismatched unrelated donor	26
the risk for	26
higher number of	26
and multiple myeloma	26
but not in	26
lower incidence of	26
donor chimerism was	26
in aml patients	26
percentage of patients	26
which may be	26
were performed using	26
the immunocompromised host	26
and high risk	26
survival rate was	26
with aml in	26
acute gvhd in	26
respiratory viruses in	26
cord blood in	26
stem cells was	26
admitted to the	26
more than months	26
were positive for	26
in both patients	26
in up to	26
kg body weight	26
patients presented with	26
she was treated	26
after autologous stem	26
course was complicated	26
retrospectively analyzed the	26
who were treated	26
even in the	26
to explore the	26
reported to the	26
for patients receiving	26
statistically significant differences	26
alive and disease	26
chronic lymphocytic leukemia	26
did not develop	26
this case highlights	26
no history of	26
from to years	26
t cell therapy	26
the ci of	26
patients and their	26
analysis of patients	26
the exception of	26
been used in	26
to characterize the	26
part of a	26
patients with and	26
patients had an	26
of conditioning regimen	26
different time points	26
and it is	26
in cvid patients	26
wide range of	26
in most cases	26
three patients had	26
first year after	26
disease in the	26
for hematopoietic stem	26
the first month	26
primary immune deficiencies	26
there is an	26
has been demonstrated	26
a higher incidence	26
conditioning regimens and	26
similar to those	26
were performed with	25
in pts and	25
at least days	25
mg kg for	25
after allogeneic sct	25
data was collected	25
ranged from to	25
our experience with	25
hematopoetic stem cell	25
who received an	25
he had a	25
patients were evaluated	25
our understanding of	25
of t and	25
factors for the	25
or peripheral blood	25
hsct between and	25
the clinical features	25
of care for	25
at one year	25
bacterial and fungal	25
group for blood	25
role of the	25
been used for	25
was years old	25
cd b cells	25
all pts received	25
marrow transplantation in	25
host disease in	25
and hsct recipients	25
have been performed	25
very good partial	25
effect on the	25
the cd cd	25
between both groups	25
the production of	25
adults and children	25
in the analysis	25
used to compare	25
and development of	25
retrospective cohort study	25
allogeneic and autologous	25
a part of	25
in elderly patients	25
he was found	25
was noted in	25
as early as	25
should not be	25
based on these	25
result in a	25
not statistically different	25
our results suggest	25
in group b	25
gvhd prophylaxis in	25
the gastrointestinal tract	25
of high risk	25
with active disease	25
decrease in the	25
vitro and in	25
underwent allogeneic hsct	25
known about the	25
group compared to	25
statistical analysis was	25
complete resolution of	25
and reduced intensity	25
it is a	25
five patients had	25
of hsct in	25
and there was	25
t cells was	25
stem cell grafts	25
after months of	25
transplantation in children	25
transplant recipients and	25
of clinical immunology	25
case series of	25
cells from the	25
is a safe	25
inborn errors of	25
are required to	25
were eligible for	25
study aimed to	25
from day to	25
haploidentical hematopoietic stem	25
the cost of	25
was performed and	25
in three patients	25
relapse or progression	25
recipients of hematopoietic	25
median day of	25
a review of	25
and viral infections	25
cells per kg	25
during the last	25
had a higher	25
at and months	25
patients should be	25
and young adult	25
the university of	25
as an alternative	25
peripheral stem cell	25
deficiency is a	25
in of them	25
is difficult to	25
the last decade	25
describe a case	25
cord blood transplant	25
was supported by	25
to healthy controls	25
of days after	25
in line with	25
data indicate that	25
it is unclear	25
significant difference was	25
for acute leukemia	24
the recovery of	24
one patient received	24
in the haplo	24
in two cases	24
at diagnosis of	24
the moment of	24
more than years	24
undergoing allogeneic hematopoietic	24
the immune response	24
did not reach	24
in the graft	24
patients in our	24
may be used	24
and the number	24
host disease and	24
clinical manifestations of	24
nothing to disclose	24
the first day	24
with autologous stem	24
the clinical presentation	24
was performed at	24
the period of	24
of minimal residual	24
dose chemotherapy with	24
with haematological malignancies	24
in spite of	24
patients with suspected	24
to identify patients	24
a patient who	24
the application of	24
cd cd cells	24
prior to transplantation	24
within days after	24
at different time	24
stem cell sources	24
the normal range	24
were not statistically	24
diseases working party	24
was no statistically	24
after days of	24
to better understand	24
for bone marrow	24
been previously reported	24
european group for	24
more than days	24
the pediatric population	24
t cells to	24
patients compared to	24
in stem cell	24
allogeneic peripheral blood	24
obtained from the	24
each of the	24
mortality after allogeneic	24
after hsct was	24
it is possible	24
years overall survival	24
to the ebmt	24
pulmonary function tests	24
nature of the	24
overall survival for	24
and days after	24
be used in	24
in some patients	24
time of months	24
in a child	24
under the curve	24
all patients achieved	24
for those with	24
characterized by a	24
the first report	24
risk of graft	24
january to december	24
not been previously	24
similar to the	24
progression to lrti	24
classified according to	24
retrospective study was	24
common cause of	24
a treatment option	24
at diagnosis and	24
duration of neutropenia	24
of immune reconstitution	24
for multiple myeloma	24
who underwent asct	24
the university hospital	24
is an autosomal	24
in a pediatric	24
differences were observed	24
a single institution	24
between and in	24
source was bone	24
of immune dysregulation	24
defined as a	24
received a second	24
of the oral	24
based conditioning regimen	24
died because of	24
mainly due to	24
was positive for	24
present the case	24
received a median	24
patients aged years	24
the extent of	24
in cr and	24
number of days	24
therapy for patients	24
age at the	24
haploidentical hsct with	24
months to years	24
up to months	24
is not clear	24
hsct is a	24
due to relapse	24
were male and	24
at months was	24
a partial response	24
by autologous stem	24
study of patients	24
in the table	24
of graft versus	23
the generation of	23
no differences were	23
that did not	23
allogenic hematopoietic stem	23
year old female	23
in blood and	23
the rates of	23
it may be	23
day for days	23
compared with those	23
be explained by	23
function mutations in	23
marrow transplantation for	23
the need of	23
immune reconstitution and	23
was shown to	23
a large cohort	23
in paediatric patients	23
the time to	23
may also be	23
in the period	23
considered in patients	23
found that the	23
incidence of cgvhd	23
four patients were	23
is a retrospective	23
our institution between	23
the t cell	23
to patients who	23
included patients with	23
side effects were	23
with the aim	23
in the donor	23
the same donor	23
cd cells infused	23
were analyzed for	23
records of patients	23
treatment in patients	23
x cd kg	23
for up to	23
patients with cd	23
complete blood count	23
response rate was	23
relapse free survival	23
an allogeneic hsct	23
flow cytometry and	23
of the current	23
alone or in	23
in the remaining	23
without evidence of	23
in the conditioning	23
cumulative incidences of	23
leading to a	23
number of infused	23
of respiratory viral	23
is a feasible	23
cmv infection in	23
goal of this	23
hsct in children	23
the patient received	23
patients with r	23
show that the	23
a high incidence	23
our aim was	23
first line therapy	23
were males and	23
gain of function	23
in four patients	23
activation of the	23
and hsct patients	23
cell transplantation and	23
time to engraftment	23
cells in patients	23
which can be	23
mortality in patients	23
patients received myeloablative	23
haematopoietic cell transplantation	23
virus infections after	23
during the period	23
lost to follow	23
patients died due	23
a single dose	23
those who received	23
two or more	23
abdominal pain and	23
in the pre	23
these patients is	23
mechanism of action	23
characterized by the	23
as compared with	23
were present in	23
heterozygous mutation in	23
of hsct for	23
dose chemotherapy followed	23
were seen in	23
significant reduction in	23
of the transplant	23
department of hematology	23
and gvhd prophylaxis	23
with no evidence	23
can result in	23
we retrospectively analysed	23
received bone marrow	23
series of patients	23
to confirm the	23
of disease relapse	23
which has been	23
patients were male	23
university hospital of	23
heterozygous mutations in	23
significantly different between	23
last follow up	23
was documented in	23
dose of cd	23
patients suffered from	23
in adults and	23
evaluate the efficacy	23
and associated with	23
be used for	23
mild to moderate	23
higher than the	23
between day and	23
one hundred and	23
risk of cmv	23
after weeks of	23
patients with cgvhd	23
in older patients	23
complication after allogeneic	23
stem cell transplantations	23
therapeutic option for	23
patients with no	23
nk cells and	23
after hematopoietic cell	23
related and unrelated	23
appeared to be	23
the relapse rate	23
cmv reactivation and	23
the patient has	23
not seem to	23
in cases and	22
patient did not	22
our center between	22
a marker of	22
levels were measured	22
prevention and treatment	22
not been reported	22
as shown in	22
a high mortality	22
all patients and	22
in the atg	22
of the initial	22
and could be	22
an increase of	22
cells were isolated	22
during the follow	22
pneumonia syndrome after	22
at any time	22
is required to	22
with relapsed or	22
limited number of	22
the median day	22
were significantly associated	22
percentage of cd	22
years in the	22
at day after	22
of the literature	22
were within normal	22
it is also	22
many of the	22
regimen consisting of	22
effective treatment for	22
cd cells and	22
the choice of	22
were as follows	22
and symptoms of	22
a median number	22
of the chest	22
not have a	22
with common variable	22
are still alive	22
cmv reactivation was	22
at the beginning	22
higher rates of	22
m for days	22
data of patients	22
of those who	22
were determined by	22
the emergence of	22
institutional review board	22
and all patients	22
fever and neutropenia	22
we reviewed the	22
patients responded to	22
the field of	22
the initiation of	22
and those with	22
four patients with	22
this may be	22
ci of relapse	22
to those with	22
outcomes in patients	22
treatment of choice	22
a haploidentical donor	22
at days and	22
as measured by	22
in this analysis	22
the diagnosis and	22
no conflicts of	22
in the incidence	22
infection in hsct	22
adenovirus infection in	22
out of pts	22
of gvhd in	22
cytotoxic t cells	22
of life of	22
the incidences of	22
of viral infections	22
our center from	22
or absence of	22
is consistent with	22
patients in this	22
were retrospectively analyzed	22
a panel of	22
to the patient	22
had significantly higher	22
due to infection	22
median of months	22
of life and	22
of relapse after	22
occurred at a	22
of this approach	22
patients with cvid	22
in cancer patients	22
are alive with	22
with more than	22
with the addition	22
had a history	22
hsct recipients and	22
these findings suggest	22
she had a	22
x kg and	22
duration of treatment	22
past medical history	22
intensity conditioning regimens	22
the timing of	22
disease of the	22
the overall response	22
in those patients	22
months post transplant	22
obliterans organizing pneumonia	22
following allogeneic stem	22
none of them	22
authors declare no	22
at months post	22
especially in patients	22
very high risk	22
in of pts	22
negative impact on	22
all patients was	22
use of plerixafor	22
results of this	22
in those who	22
responsible for the	22
acute respiratory failure	22
was not different	22
acute gvhd of	22
average number of	22
use of the	22
the ebmt registry	22
number of previous	22
moderate and severe	22
day after hsct	22
she did not	22
first case of	22
patients with recurrent	22
the clinical course	22
considered in the	22
the distribution of	22
majority of cases	22
available for patients	22
the follow up	22
after completion of	22
objective was to	22
prior to allo	22
bronchiolitis obliterans organizing	22
patients was months	22
a cause of	22
as soon as	22
diagnosed in patients	22
development of allo	22
these results are	22
total dose of	22
early diagnosis of	22
in cases with	22
were tested for	22
had a significant	22
aim of our	22
outcome of allogeneic	22
been treated with	22
from matched related	22
peripheral stem cells	22
index of suspicion	22
of acute or	21
prospective study of	21
has resulted in	21
the study group	21
to the best	21
and as a	21
relapse after allogeneic	21
adoptive transfer of	21
in a larger	21
chronic lung disease	21
is defined as	21
hsct was performed	21
patients developed acute	21
with cmv reactivation	21
invasive pulmonary aspergillosis	21
developed in patients	21
the major cause	21
stem cell graft	21
would like to	21
influenza a and	21
and it was	21
in our hospital	21
which is a	21
of graft rejection	21
data from the	21
of unknown origin	21
os and efs	21
potential risk factors	21
transplant was years	21
due to an	21
of infused cd	21
a significant proportion	21
for prevention of	21
to patients without	21