bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
serum samples	737
mg kg	667
extracellular vesicles	599
summary conclusion	561
immune response	537
ng ml	531
cell lines	525
western blot	511
influenza virus	507
control group	493
flow cytometry	467
present study	462
gene expression	461
significantly higher	443
pg ml	419
blood samples	356
mg ml	352
bone marrow	348
cell line	339
amino acid	335
peripheral blood	332
influenza viruses	311
cd cd	309
linked immunosorbent	297
immunosorbent assay	287
statistically significant	280
specific ige	273
results suggest	272
performed using	272
whole blood	272
significant difference	269
monoclonal antibodies	265
respiratory syndrome	260
cancer cells	258
breast cancer	258
important role	257
significant differences	257
acute respiratory	255
endothelial cells	254
electron microscopy	253
immune responses	253
allergic rhinitis	251
immune system	251
cell culture	248
clinical signs	241
mrna expression	236
time pcr	235
mg dl	232
significantly increased	230
oxidative stress	230
cell proliferation	228
pandemic influenza	226
protein expression	221
inflammatory response	215
monoclonal antibody	213
severe acute	211
specific antibodies	210
antibody responses	208
porcine epidemic	207
seasonal influenza	206
indirect elisa	206
public health	203
western blotting	198
infected cells	198
years old	197
antibody response	197
room temperature	197
cell surface	197
stem cells	197
significantly reduced	196
mean age	192
mass spectrometry	192
significantly lower	189
epithelial cells	189
risk factors	188
commercially available	186
virus infection	186
dependent manner	185
data suggest	184
results indicate	178
epidemic diarrhea	176
molecular weight	173
nitric oxide	171
previously described	171
respiratory tract	171
pregnant women	170
results showed	170
smooth muscle	170
body weight	169
significant increase	168
type i	168
cancer cell	167
cell death	166
blood pressure	166
two groups	165
growth factor	164
stem cell	163
dendritic cells	163
spike protein	162
healthy controls	162
first time	162
high levels	162
infectious diseases	160
avian influenza	159
nucleic acid	159
wild type	157
nucleocapsid protein	157
neutralizing antibodies	156
statistical analysis	155
antibody titers	155
serological assays	154
hong kong	154
united states	153
chain reaction	153
amino acids	153
positive results	152
food allergy	152
cell types	150
cell activation	150
negative control	150
diarrhea virus	150
skin prick	148
cytokine production	147
cell cycle	147
elisa kit	146
derived evs	146
blot analysis	145
polymerase chain	145
cord uid	143
doc id	143
significantly different	142
mast cells	142
serum levels	142
escherichia coli	142
septic shock	141
three times	141
inflammatory cytokines	140
real time	140
nanoparticle tracking	139
prostate cancer	138
determine whether	138
lateral flow	138
igg antibodies	136
tracking analysis	135
class i	134
side effects	134
lg ml	133
widely used	133
mrna levels	132
necrosis factor	132
expression levels	131
lymph nodes	131
author funder	130
granted medrxiv	130
transmissible gastroenteritis	128
significantly decreased	127
cancer patients	127
plasma samples	127
gestational age	126
determined using	126
time points	125
cell responses	124
recombinant protein	124
mouse model	124
samples collected	123
analysis revealed	122
risk factor	122
acute phase	121
days post	121
cd cells	120
clinical trials	120
mononuclear cells	120
measured using	119
copyright holder	118
positive samples	118
may contribute	118
pcr assay	117
differentially expressed	117
may play	116
previous studies	116
findings suggest	115
results obtained	115
specific antibody	115
results show	115
atopic dermatitis	115
surface plasmon	114
tumor necrosis	114
goat anti	114
staphylococcus aureus	114
analyzed using	113
positive control	113
gel electrophoresis	113
elisa method	112
ebola virus	112
culture medium	112
case report	111
version posted	111
transcription factor	111
grass pollen	110
blood flow	110
cell viability	110
median age	110
immune cells	109
specific igg	109
innate immune	109
fold increase	109
commonly used	109
protein levels	109
plasmon resonance	108
current study	108
logistic regression	107
syndrome coronavirus	107
university hospital	107
mast cell	106
healthy volunteers	106
previously reported	106
least one	104
predictive value	104
exclusion chromatography	103
molecular mechanisms	102
patients treated	102
two different	101
analysis showed	101
adhesion molecules	101
organ failure	100
test results	100
may also	100
plasma levels	100
type ii	100
three different	100
human serum	100
influenza vaccine	99
fecal samples	99
ex vivo	99
time rt	99
medical center	99
structural proteins	99
blood donors	98
informed consent	98
fcov type	98
neutralizing antibody	97
total ige	97
endothelial cell	97
year old	96
nervous system	96
taken together	96
bovine serum	95
nkt cells	95
animal models	95
extracellular matrix	94
capillary electrophoresis	94
virus isolation	94
cell cultures	93
transmission electron	93
based elisa	93
recent studies	93
results demonstrate	93
care workers	92
allergic patients	92
adverse events	92
insulin resistance	92
also observed	92
nk cells	92
wound healing	91
optical density	91
infectious bronchitis	91
derived exosomes	91
novel coronavirus	90
total rna	90
well plates	90
specific cd	90
deficient mice	90
weight loss	90
may provide	89
increased risk	89
higher levels	89
gastroenteritis virus	89
statistical significance	89
sandwich elisa	89
mesenchymal stem	89
signal transduction	88
culture media	88
vip aa	88
elisa using	87
iu ml	87
clinical samples	87
may lead	87
binding protein	87
plasma membrane	87
lung cancer	87
viral infections	87
wide range	87
significant reduction	87
sequence analysis	87
inflammatory mediators	86
disease severity	86
igg antibody	86
total protein	86
healthy individuals	86
house dust	85
three groups	85
proinflammatory cytokines	85
tissue culture	85
negative controls	84
rheumatoid arthritis	84
tumor cells	84
capture elisa	84
intensive care	84
control groups	84
experimentally infected	83
one patient	83
secondary antibody	83
plasma cells	83
peer review	83
data indicate	83
high sensitivity	83
size exclusion	83
th cells	83
mhc class	83
blood cells	82
growth factors	82
reactive oxygen	82
sars coronavirus	82
infectious disease	82
prick test	82
closely related	82
extracellular vesicle	82
positive correlation	82
made available	82
usa introduction	82
ige levels	81
also found	81
prick tests	81
viral rna	81
healthy subjects	81
recombinant proteins	81
data show	81
ovarian cancer	81
healthy donors	81
long term	81
nucleic acids	80
age groups	80
united kingdom	80
od values	80
positive sera	79
dna damage	79
increased expression	79
first trimester	79
elisa kits	79
serum albumin	79
elisa test	78
transcription factors	78
inhibitory effect	78
reactive protein	78
dust mite	78
regression analysis	78
antibody levels	78
protective effect	77
serological tests	77
significant decrease	77
antibody titer	77
inflammatory responses	77
antibody detection	77
diagnostic tests	76
amniotic fluid	76
inflammatory diseases	76
study group	76
bronchitis virus	76
reverse transcription	76
international license	76
study design	75
density gradient	75
study period	75
fetal growth	74
platelet activation	74
blood mononuclear	74
health care	74
serum sample	74
positive serum	74
igg elisa	73
clinical trial	73
experimental infection	73
fusion protein	73
neutralization assay	73
elisa assay	73
infected mice	73
viral load	73
per well	73
time point	73
similar results	73
clinical symptoms	73
virus replication	72
expression level	72
platelet aggregation	72
heart rate	72
gold standard	72
mdck cells	72
signaling pathways	72
body mass	71
skeletal muscle	71
allergic reactions	71
blocking elisa	71
high level	71
oxygen species	71
kg day	70
significant correlation	70
autoimmune diseases	70
data demonstrate	70
dose dependent	70
cov infection	70
patients received	70
previously shown	70
derived extracellular	70
muscle cells	70
swine influenza	69
umbilical cord	69
within hours	69
surface markers	69
phage display	69
tested positive	69
receptor binding	69
recipient cells	69
fatty acids	69
key role	69
tract infections	68
detection limit	68
viral infection	68
standard deviation	68
early detection	68
septic patients	68
well tolerated	68
high affinity	68
significantly associated	68
evaluated using	68
highly sensitive	68
preliminary results	68
colorectal cancer	68
liquid chromatography	68
spinal cord	68
study showed	67
respiratory syncytial	67
skin test	67
egg yolk	67
commercial elisa	67
severe disease	67
airway inflammation	67
treated mice	67
infected animals	66
buffered saline	66
increased levels	66
protein kinase	66
using elisa	66
central nervous	66
treatment groups	66
serological assay	66
diabetes mellitus	66
early diagnosis	66
human influenza	66
heart failure	65
control subjects	65
multiple organ	65
type diabetes	65
elisa plates	65
serial dilutions	65
disease control	65
class ii	65
disease virus	65
acid sequence	65
ob gyn	64
target cells	64
control animals	64
phylogenetic analysis	64
faecal samples	64
high risk	64
clinical practice	64
red blood	64
urinary tract	64
physical examination	64
human plasma	64
patients without	63
elisa results	63
even though	63
fatty acid	63
colloidal gold	63
large number	63
low levels	63
group i	63
influenza pandemic	63
cutoff value	63
platelet count	63
liquid biopsy	63
clinical isolates	63
respiratory disease	63
activated protein	63
health organization	63
flow serological	63
world health	63
affinity chromatography	63
molecular biology	63
old female	63
virus strains	62
highly pathogenic	62
conditioned media	62
new york	62
preliminary data	62
medrxiv preprint	62
treatment group	62
higher sensitivity	62
stromal cells	62
potential role	62
crucial role	62
mortality rate	62
expression vector	62
false positive	62
skin tests	62
old male	62
natural killer	62
hepatitis virus	61
detect antibodies	61
sars patients	61
diagnostic methods	61
cell receptor	61
poorly understood	61
cells expressing	61
coronavirus disease	61
prospective study	61
confocal microscopy	61
critical role	61
influenza infection	61
syncytial virus	61
highly conserved	61
surfactant protein	61
ko mice	60
family members	60
rapid detection	60
biological activity	60
also used	60
tgev prcv	60
upper respiratory	60
low dose	60
negative sera	60
skin testing	60
negative results	60
described previously	60
cell adhesion	60
fold higher	60
naturally infected	60
elisa assays	59
genomic dna	59
middle east	59
horseradish peroxidase	59
binding domain	59
preterm birth	59
two weeks	59
receptor antagonist	59
enzyme activity	59
sars cov	59
high dose	59
serum concentrations	59
surface expression	59
cell lysates	58
specific primers	58
samples obtained	58
small rna	58
plasma concentrations	58
ms ms	58
one year	58
cohort study	58
patients undergoing	58
cd expression	58
quality control	58
positive cells	58
study aimed	58
control antigen	58
myocardial infarction	58
serum antibody	58
also tested	57
primary care	57
multiple sclerosis	57
treated patients	57
negative serum	57
virus neutralization	57
bl mice	57
clinically relevant	57
assessed using	57
allergic asthma	57
cell type	57
lung injury	57
research institute	57
adaptive immune	57
naturally occurring	57
luminex assay	57
ev isolation	57
apoptotic cells	57
family history	56
studies showed	56
lipid peroxidation	56
od value	56
recent years	56
humoral immune	56
assay using	56
two patients	56
high specificity	56
inkt cells	56
total number	56
asthma symptoms	56
healthy dogs	56
bronchoalveolar lavage	56
venous blood	56
calculated using	56
university medical	56
isolated using	56
pbs containing	56
mouth disease	55
severe asthma	55
analysis using	55
times higher	55
animal model	55
normal range	55
human coronavirus	55
future studies	55
treated cells	55
critically ill	55
clinical studies	55
disease activity	55
pilot study	55
inflammatory bowel	55
confidence interval	55
cell response	55
innate immunity	55
cell growth	55
menstrual cycle	55
washed three	55
cord blood	55
clinical disease	54
healthy control	54
lung function	54
major role	54
sample size	54
cell function	54
protein content	54
igm antibodies	54
asthma control	54
symptom onset	54
bacterial infections	54
cells treated	54
convalescent plasma	54
viruses isolated	54
low molecular	54
size distribution	54
respiratory symptoms	54
ml min	54
significantly greater	54
vero cells	54
hours post	54
guinea pig	54
culture supernatants	53
also showed	53
increased significantly	53
conditioned medium	53
positive predictive	53
viral replication	53
polyacrylamide gel	53
drug resistance	53
diagnostic accuracy	53
tumour cells	53
patients receiving	53
chronic inflammatory	53
lymph node	53
control mice	53
lower respiratory	53
therapeutic potential	53
type mice	53
elevated levels	53
antigen presentation	53
cytopathic effect	53
trophoblast cells	53
analysed using	52
significantly elevated	52
may result	52
bacterial infection	52
serially diluted	52
viral antigen	52
pseudomonas aeruginosa	52
elisa system	52
care unit	52
inflammatory cytokine	52
considered positive	52
diagnostic performance	52
strains isolated	52
considered significant	52
nasal spray	52
serum dilution	52
placebo group	52
transgenic mice	52
general population	52
one hour	52
allergic diseases	52
blood cell	52
age group	52
different types	52
viral proteins	52
resistant strains	52
early stage	52
patients suffering	52
immunofluorescence assay	51
reverse transcriptase	51
cells showed	51
preterm delivery	51
group compared	51
factor viii	51
treated animals	51
serum antibodies	51
may represent	51
respiratory distress	51
signaling pathway	51
showed significant	51
porcine respiratory	51
infected patients	51
ultrasensitive elisa	51
east respiratory	51
neutralization test	51
negative samples	51
influenza vaccines	50
mycobacterium tuberculosis	50
urine samples	50
respiratory coronavirus	50
protective immunity	50
time course	50
rights reserved	50
leaf curl	50
protein level	50
clinical chemistry	50
cerebrospinal fluid	50
blood glucose	50
hydrogen peroxide	50
polyclonal antibodies	50
vg vd	50
weight gain	50
flow cytometric	50
mouse igg	50
results indicated	50
presenting cells	50
high prevalence	49
bronchial asthma	49
full length	49
compared using	49
three patients	49
growth restriction	49
thermo fisher	49
binding sites	49
also significantly	49
preterm labor	49
mass index	49
mouse hepatitis	48
tnf production	48
one hundred	48
primary human	48
guinea pigs	48
antibiotic therapy	48
cell migration	48
protein synthesis	48
differential ultracentrifugation	48
laboratory mice	48
quantitative rt	48
detected using	48
antigen presenting	48
like particles	48
clinical diagnosis	48
intercellular communication	48
blood plasma	48
blood cultures	48
hospitalized patients	48
healthcare workers	48
last years	48
cellular immune	48
days later	48
patients compared	47
autoimmune disease	47
alkaline phosphatase	47
also performed	47
one week	47
abdominal pain	47
low concentrations	47
phage clones	47
clinical data	47
well known	47
obtained using	47
survival rate	47
small extracellular	47
differential expression	47
study demonstrates	47
sample collection	47
previous study	47
cell count	47
medical records	47
respiratory viruses	47
highly purified	47
blood culture	47
mechanisms underlying	47
epidemiological studies	47
mm nacl	47
food allergens	47
ca i	47
final concentration	47
also known	46
host response	46
ns protein	46
based assay	46
viral antigens	46
tested using	46
different concentrations	46
like receptors	46
protein concentration	46
infectious agents	46
randomly selected	46
performed according	46
western blots	46
investigate whether	46
within minutes	46
specific igy	46
high concentrations	46
enzyme immunoassay	46
six months	46
birth weight	46
may cause	46
central role	46
better understanding	46
using flow	46
human myometrium	46
clinical course	46
retrospective study	46
national institute	46
day post	46
adipose tissue	46
healthy blood	45
study included	45
vp protein	45
lymphocytic choriomeningitis	45
patients showed	45
north america	45
isolation methods	45
cells using	45
elisa tests	45
control cells	45
dna vaccine	45
apoptotic cell	45
study population	45
persistent asthma	45
significant changes	45
cytokine levels	45
host defense	45
pregnant rats	45
significant association	45
expression system	45
dawley rats	45
wistar rats	45
cell membrane	45
vascular endothelial	45
connective tissue	45
detection antibody	45
tissue factor	45
virus antigen	45
induced apoptosis	45
viral shedding	45
ic values	44
tyrosine kinase	44
fluorescence microscopy	44
data analysis	44
uric acid	44
blood loss	44
igg levels	44
first study	44
high degree	44
signalling pathways	44
results demonstrated	44
receptor expression	44
isolated evs	44
single nucleotide	44
vaccine strain	44
respiratory infections	44
like receptor	44
binding site	44
pivotal role	44
ev markers	44
human blood	44
inflammatory cells	44
stranded rna	44
way anova	44
study shows	44
using different	44
several studies	44
adhesion molecule	44
cell population	44
diagnostic test	44
positive result	44
also evaluated	44
single dose	44
apc resistance	44
fisher scientific	44
food allergies	44
inhibitory effects	44
bowel disease	44
may occur	44
superoxide dismutase	44
evs derived	44
cell differentiation	44
data suggests	43
investigated whether	43
ae log	43
organ dysfunction	43
marburg virus	43
systemic inflammatory	43
newly developed	43
heart disease	43
also increased	43
mouse ifn	43
studies suggest	43
levels increased	43
two hours	43
normal human	43
weeks gestation	43
membrane protein	43
detection methods	43
proteomic analysis	43
four different	43
human umbilical	43
arachidonic acid	43
using two	43
nasal congestion	43
ev cargo	43
functional assays	42
correlation coefficient	42
free radical	42
may affect	42
human igg	42
capture antibody	42
acute pancreatitis	42
control samples	42
iga elisa	42
genes encoding	42
cell development	42
pcr assays	42
patient sera	42
causative agent	42
differential diagnosis	42
disease progression	42
exact test	42
serum ige	42
arterial blood	42
adverse reactions	42
mg bid	42
high throughput	42
chronic disease	42
cell populations	42
negative correlation	42
clinical specimens	42
hemorrhagic shock	42
lung tissue	42
mouse models	42
fetal membranes	42
potential use	42
human sera	42
specific iga	42
within days	42
epithelial cell	42
viral particles	42
differential centrifugation	42
umbilical vein	42
peanut allergy	42
may explain	41
ug ml	41
specific binding	41
cesarean section	41
studies will	41
first step	41
fusion proteins	41
host immune	41
vaccine development	41
significantly inhibited	41
tissue damage	41
cell subsets	41
producing cells	41
immunochromatographic strip	41
children aged	41
state university	41
tissue samples	41
ev release	41
i molecules	41
adverse effects	41
high mortality	41
virus infections	41
clostridium difficile	41
significantly improved	41
pathogenic avian	41
negative predictive	41
beneficial effects	40
gene segments	40
lactate dehydrogenase	40
murine model	40
diagnostic sensitivity	40
highly specific	40
currently available	40
host cells	40
relatively high	40
chronic urticaria	40
phase i	40
blood count	40
brain tissue	40
conducted using	40
culture supernatant	40
genes involved	40
based elisas	40
nuclear factor	40
reperfusion injury	40
systemic lupus	40
asthmatic patients	40
control serum	40
direct contact	40
oxide synthase	40
leading cause	40
house elisa	40
surface area	40
linear regression	40
new therapeutic	40
associated coronavirus	40
induced thrombocytopenia	40
tumor cell	39
tested negative	39
using specific	39
adaptive immunity	39
quantified using	39
chicken eggs	39
may help	39
positive skin	39
data obtained	39
ige level	39
antibody titres	39
cleavage site	39
decreased significantly	39
antigen capture	39
different doses	39
recombinant nucleocapsid	39
pcr analysis	39
diabetic patients	39
mechanisms involved	39
pcr positive	39
lupus erythematosus	39
acid residues	39
frequently used	39
specific siga	39
fat diet	39
renal failure	39
specific immune	39
multiplex pcr	39
will help	39
effective treatment	39
evs isolated	39
present work	39
large scale	39
identified using	39
different cell	39
heat shock	39
tumor growth	39
virus isolates	39
first wave	39
three days	39
cell survival	39
possible role	39
immune cell	39
streptococcus pneumoniae	39
antibody testing	38
statistical analyses	38
group ii	38
potential therapeutic	38
rapid diagnosis	38
circulating levels	38
peritoneal macrophages	38
rat model	38
particle size	38
university school	38
using standard	38
infected dogs	38
inclusion criteria	38
gram negative	38
folic acid	38
allergic reaction	38
see table	38
choriomeningitis virus	38
much higher	38
ill patients	38
expression pattern	38
viral diseases	38
higher risk	38
remains unclear	38
absorbance values	38
sle patients	38
chronic inflammation	38
different time	38
pcr amplification	38
animal health	38
better understand	38
low level	38
small number	38
pcr using	38
infected individuals	38
cfu ml	38
human ifn	38
progenitor cells	38
antimicrobial resistance	38
mg day	38
total antibody	38
factors associated	38
renal function	38
skin lesions	38
infected pigs	37
recombinant human	37
rabbit anti	37
human lung	37
control study	37
wt mice	37
study suggests	37
expression profiles	37
old woman	37
written informed	37
may serve	37
expression profile	37
promoter activity	37
antimicrobial activity	37
outer membrane	37
purified using	37
two methods	37
laboratory tests	37
target genes	37
pdm virus	37
growth hormone	37
serological testing	37
cells may	37
based assays	37
birch pollen	37
applied biosystems	37
evs released	37
per day	37
human monocytes	37
human cells	37
false positives	37
posted september	37
endoplasmic reticulum	37
medical school	37
vascular smooth	37
animal species	37
conjugated goat	37
common cause	37
influenza surveillance	37
cardiovascular disease	37
milk allergy	37
pandemic virus	37
year period	37
showed higher	37
distress syndrome	37
polyclonal antibody	37
positive elisa	37
elisa based	37
hypersensitivity reactions	37
broad spectrum	37
antibody tests	37
function tests	37
pulmonary disease	37
free ultrasensitive	36
first report	36
nk cell	36
diagnostic assays	36
cervical ripening	36
tract infection	36
hla class	36
diagnostic tool	36
drug delivery	36
cells compared	36
findings indicate	36
showed high	36
ethics committee	36
significantly less	36
available elisa	36
cystic fibrosis	36
scid mice	36
coronavirus spike	36
inflammatory processes	36
influenza vaccination	36
positively correlated	36
veterinary medicine	36
cell communication	36
european countries	36
situ hybridization	36
relatively low	36
converting enzyme	36
pulmonary hypertension	36
well plate	36
positive test	36
four patients	36
like viruses	36
virus ns	36
also determined	36
clinical use	36
live attenuated	36
biologically active	36
dna sequencing	36
immunosorbent assays	36
control sera	35
simultaneous detection	35
significant improvement	35
free radicals	35
antibiotic treatment	35
ge healthcare	35
white blood	35
data support	35
breast milk	35
significant role	35
pcr products	35
women undergoing	35
provocation test	35
significantly correlated	35
barr virus	35
related genes	35
laboratory testing	35
significant effect	35
disease onset	35
binding proteins	35
binding affinity	35
assay results	35
high incidence	35
indirect elisas	35
average age	35
tissue injury	35
rapid test	35
structural protein	35
quantitative real	35
positive reactions	35
phase ii	35
two years	35
induced arthritis	35
specific immunotherapy	35
poor prognosis	35
gradient centrifugation	35
previously demonstrated	35
data showed	35
immunized mice	35
mm tris	35
coronavirus infection	35
well established	35
also demonstrated	35
human peripheral	35
authors declare	35
lower levels	35
antibody production	35
bile acid	34
virus strain	34
biochemical parameters	34
sequence homology	34
cell wall	34
glucose tolerance	34
vaccinated animals	34
good correlation	34
ige binding	34
colon cancer	34
twice daily	34
human macrophages	34
protective effects	34
mean values	34
apache ii	34
major cause	34
using recombinant	34
asthma severity	34
medical history	34
standard curve	34
may influence	34
per year	34
hemorrhagic fever	34
inclusion bodies	34
four times	34
adult patients	34
may reflect	34
standard deviations	34
antibodies specific	34
ev subpopulations	34
fetal brain	34
therapeutic agents	34
insect cells	34
wide variety	34
single cell	34
thrombin generation	34
five patients	34
enzyme linked	34
early stages	34
mitochondrial membrane	34
surveillance system	34
left ventricular	34
studies using	34
results may	34
small intestine	34
plasma evs	34
cytotoxic effect	34
clinical manifestations	34
allergic inflammation	34
important roles	34
follicular fluid	34
antibody test	34
cardiac output	34
antibodies directed	34
asthma patients	34
plasmid dna	34
previously published	33
herpes simplex	33
cytokine expression	33
glucose levels	33
will provide	33
elisa showed	33
kindly provided	33
fast set	33
cancer stem	33
mice treated	33
exosomes derived	33
th day	33
using anti	33
specific antisera	33
purified recombinant	33
elisa format	33
therapeutic strategies	33
immune status	33
economic losses	33
antiviral activity	33
clinical outcome	33
high fat	33
bactericidal activity	33
first case	33
expression analysis	33
developed using	33
human coronaviruses	33
coronary artery	33
model system	33
sodium dodecyl	33
scanning electron	33
hepatocellular carcinoma	33
bacterial growth	33
flow cytometer	33
facs analysis	33
assay kit	33
igg detection	33
mice compared	33
fold change	33
treatment period	33
negative bacteria	33
clinical features	33
analysis indicated	33
complete blood	33
proinflammatory cytokine	33
open reading	33
spleen cells	33
replacement therapy	33
roc curve	33
mcg ml	33
among patients	33
blood levels	33
two distinct	33
seasonal allergic	33
ct scan	33
mean value	33
mouse serum	33
promoter region	32
two major	32
dna methylation	32
genome sequence	32
vitro studies	32
geometric mean	32
sensitive detection	32
mediated immune	32
milk samples	32
protein expressed	32
rotavirus infection	32
oral administration	32
definitive diagnosis	32
young children	32
largely unknown	32
pollen season	32
coating antigen	32
luciferase reporter	32
many different	32
cell carcinoma	32
blood serum	32
susceptibility testing	32
syndrome virus	32
immunocompetent mice	32
egg white	32
epidemic diarrhoea	32
washed times	32
rna extraction	32
consecutive days	32
clinical characteristics	32
science foundation	32
mtt assay	32
coronavirus infections	32
done using	32
serum igg	32
tumour growth	32
purified protein	32
time consuming	32
pathway analysis	32
diagnostic value	32
female mice	32
highly expressed	32
heavy chain	32
matrix metalloproteinases	32
body fluids	32
mice showed	32
biological samples	32
inhibition assay	32
passive immunotherapy	32
emergency department	32
tumour microenvironment	32
values obtained	32
nucleotide sequences	32
clinical efficacy	32
using serum	32
disk diffusion	32
medical research	32
protein cargo	32
early pregnancy	31
plasminogen activator	31
dna vaccines	31
asthma exacerbation	31
performance liquid	31
weeks later	31
immunoblot analysis	31
mice infected	31
teaching hospital	31
male wistar	31
treated rats	31
nuclear translocation	31
gene encoding	31
weeks post	31
virus infected	31
ad libitum	31
inflammatory activity	31
general anesthesia	31
distilled water	31
least two	31
patients diagnosed	31
cardiovascular diseases	31
novel therapeutic	31
vaccinia virus	31
high doses	31
mycobacterium avium	31
small evs	31
nucleotide sequence	31
healthy adult	31
synthetic peptides	31
clinical response	31
hiv infection	31
sera collected	31
clavulanic acid	31
odds ratio	31
microtiter plates	31
following treatment	31
host cell	31
clinical study	31
specific monoclonal	31
treated group	31
dust mites	31
resistant isolates	31
early phase	31
acute myocardial	31
clinical presentation	31
human disease	31
severe sepsis	31
human respiratory	31
blood collection	31
results suggested	31
fetal bovine	31
molecular mass	31
hours later	31
infectious virus	30
hemagglutination inhibition	30
signalling pathway	30
protease inhibitor	30
age years	30
target cell	30
human metapneumovirus	30
protein markers	30
research center	30
per patient	30
kidney disease	30
diarrhoea virus	30
post onset	30
pulmonary function	30
new zealand	30
cytokines il	30
granulosa cells	30
map kinase	30
less likely	30
mice lacking	30
latex agglutination	30
terminal domain	30
serum creatinine	30
symptom score	30
provide evidence	30
nasal swabs	30
cells infected	30
positive patients	30
patient samples	30
linear range	30
type specific	30
cell number	30
transforming growth	30
showed significantly	30
two days	30
infections caused	30
whole virus	30
stress response	30
type iii	30
serologic assays	30
genbank accession	30
resonance imaging	30
fasciola hepatica	30
human endometrial	30
tomato leaf	30
study provides	30
investigated using	30
recombinant baculovirus	30
also shown	30
national university	30
first week	30
challenge test	30
viral protein	30
antioxidant status	30
pedv infection	30
effector cells	30
viral loads	30
therapeutic target	30
acm device	30
enzyme activities	30
within normal	30
currently used	30
included patients	30
proteins involved	30
natural infection	30
nkt cell	30
curve analysis	30
posted july	30
seven days	30
venous thrombosis	30
four groups	29
also studied	29
th cytokines	29
secondary antibodies	29
maternal plasma	29
blood sample	29
per group	29
dna binding	29
platelet counts	29
clinical history	29
eoc cells	29
clinical relevance	29
diagnostic tools	29
inflammatory properties	29
complement system	29
confirmed cases	29
first days	29
good agreement	29
ha gene	29
many studies	29
data collection	29
thermal injury	29
roc analysis	29
cytokine secretion	29
vaccine candidates	29
ev production	29
indirect immunofluorescence	29
sialic acid	29
plaque assay	29
cell epitopes	29
platelet function	29
samples taken	29
surface marker	29
bile acids	29
elisa plate	29
body condition	29
molecular characterization	29
antigenic sites	29
patients admitted	29
medium supplemented	29
southern china	29
white matter	29
drug allergy	29
also detected	29
lavage fluid	29
antigen detection	29
vitro activity	29
diagnostic laboratory	29
pulmonary fibrosis	29
square test	29
vascular resistance	29
synovial fluid	29
one case	29
antibody binding	29
also investigated	29
pcr testing	29
regression model	29
ra patients	29
clinical laboratory	29
human cd	29
normal pregnancy	29
culture conditions	29
bacterial translocation	29
soft tissue	29
samples showed	29
plasma glucose	29
berne virus	29
flow rate	29
separation capillary	29
confidence intervals	29
recent study	29
study groups	29
plaque reduction	29
gp i	28
stool samples	28
allergic symptoms	28
decidual cells	28
patienten mit	28
infected cell	28
inflammatory disease	28
clinical setting	28
control dogs	28
viral genome	28
two types	28
brain injury	28
different species	28
ischemia reperfusion	28
isothermal amplification	28
tumor suppressor	28
evidence suggests	28
markers cd	28
pcr method	28
bacterial cells	28
research council	28
liver disease	28
environmental factors	28
dose response	28
epidermal growth	28
ml kg	28
human endometrium	28
clinical applications	28
probably due	28
study using	28
rna sequencing	28
mosaic virus	28
matched controls	28
positive controls	28
cell derived	28
calf serum	28
brain barrier	28
samples tested	28
biological materials	28
ml vs	28
neutralization assays	28
study revealed	28
genetically modified	28
infection control	28
arterial pressure	28
light scattering	28
tumour cell	28
hela cells	28
enzymatic activity	28
operating characteristic	28
igm elisa	28
significant increases	28
commercial kit	28
significant change	28
different stages	28
among women	28
cells express	28
receiver operating	28
dynamic range	28
showed similar	28
using primers	28
anaphylactic reaction	28
myeloid cells	28
virus detection	28
significantly enhanced	28
crp levels	28
knockout mice	28
like illness	28
serum concentration	28
serum il	28
secretory phase	28
fetal plasma	28
human infection	28
mean ae	27
vitro experiments	27
inflammatory conditions	27
hek cells	27
cytokine il	27
new insights	27
cellular uptake	27
chart review	27
thrombus formation	27
recent advances	27
also present	27
contact dermatitis	27
classical swine	27
treg cells	27
phosphate buffer	27
samples using	27
potential biomarkers	27
inflammatory process	27
findings may	27
gastrointestinal disease	27
mouse colonies	27
mic values	27
antibiotic resistance	27
beneficial effect	27
human placenta	27
pollen allergy	27
specific elisa	27
lung disease	27
days pos	27
six patients	27
vivo studies	27
biological fluids	27
high density	27
among children	27
fever virus	27
proteolytic activity	27
time period	27
normal dogs	27
cells mm	27
roc curves	27
recently reported	27
cervical cancer	27
fold lower	27
infected vero	27
activation markers	27
therapeutic approach	27
liver injury	27
antigen test	27
affected dogs	27
expressed genes	27
repeated measures	27
therapeutic targets	27
point mutation	27
control measures	27
leydig cells	27
clinical improvement	27
method using	27
aureus strains	27
days prior	27
assays using	27
medical university	27
culture system	27
mouse strains	27
adjuvanted vaccine	27
antigen processing	27
coat protein	27
tandem mass	27
mortality rates	27
life technologies	27
general hospital	27
whole genome	27
villous explants	27
per ml	27
aged years	27
less sensitive	27
detecting antibodies	27
study demonstrated	27
studies show	27
circulating evs	27
pancreatic cancer	27
drinking water	27
may suggest	27
reverse genetics	27
gastrointestinal tract	27
play important	27
small molecules	27
retrospective analysis	27
small animal	27
sera obtained	27
results revealed	27
mirna expression	27
diluted serum	27
acquired pneumonia	27
los angeles	27
acid sequences	27
serologic testing	27
trauma patients	27
elisa methods	27
survival time	27
log cfu	26
therapeutic approaches	26
allergic disease	26
marker vaccines	26
previous reports	26
prothrombin time	26
age range	26
fowl adenovirus	26
virus particles	26
test using	26
short term	26
serum total	26
higher concentrations	26
viral disease	26
plasma volume	26
clotting time	26
tlr ligands	26
erk activation	26
using monoclonal	26
specific detection	26
antiviral treatment	26
powerful tool	26
nasal washings	26
cells ml	26
maternal age	26
antimicrobial susceptibility	26
delivery system	26
cytokine response	26
old man	26
membrane potential	26
limited number	26
may indicate	26
total antioxidant	26
fetal sheep	26
direct elisa	26
newcastle disease	26
normal controls	26
african green	26
cytokine release	26
ige mediated	26
infection status	26
avian infectious	26
endothelial growth	26
lipid rafts	26
mice received	26
steady state	26
also reduced	26
additional studies	26
endemic areas	26
candidate genes	26
kg body	26
blood vessels	26
dendritic cell	26
north american	26
binding activity	26
companion animals	26
inflammatory effect	26
inflammatory effects	26
years ago	26
ae lg	26
medication use	26
one day	26
respiratory pathogens	26
clinical significance	26
safety profile	26
plasma concentration	26
quantitative pcr	26
major allergen	26
forming units	26
large numbers	26
mesenteric lymph	26
one sample	26
animal studies	26
intrauterine growth	26
microtiter plate	26
mediated immunity	26
many countries	26
lesser extent	26
mesenchymal stromal	26
large amounts	26
equine sera	26
regulatory role	26
exhaled breath	26
expression patterns	26
acute lung	26
noise ratio	26
using either	26
drug administration	26
respiratory diseases	26
czech republic	26
celiac disease	26
patient groups	26
reactive antibodies	26
trend towards	25
gene silencing	25
passive immunity	25
protease inhibitors	25
fetal weight	25
western immunoblot	25
biomedical research	25
transfected cells	25
factor receptor	25
generation sequencing	25
ige reactivity	25
jugular vein	25
stimulating factor	25
inhaled corticosteroids	25
ang ii	25
healthy cats	25
allergen immunotherapy	25
phosphate buffered	25
showed positive	25
virus type	25
molecular markers	25
group received	25
school children	25
post infection	25
recombinant antigen	25
pcr results	25
resistance genes	25
human parechovirus	25
barrier function	25
fully understood	25
vein endothelial	25
methods used	25
eosinophil count	25
nasal symptoms	25
surface protein	25
antimicrobial agents	25
clinically significant	25
suspect results	25
icu patients	25
normal pregnancies	25
convalescent serum	25
density lipoprotein	25
membrane fusion	25
systemic inflammation	25
humoral response	25
sectional study	25
inhibitory concentration	25
onset preeclampsia	25
mean serum	25
cancer progression	25
protein bands	25
increased il	25
epitope mapping	25
saudi arabia	25
antibiotic use	25
elderly patients	25
cigarette smoke	25
molecular mechanism	25
lps stimulation	25
health problem	25
resistant staphylococcus	25
also measured	25
strong positive	25
miu ml	25
antioxidant capacity	25
previous work	25
therapeutic effect	25
dengue virus	25
health sciences	25
increasing concentrations	25
antiviral drugs	25
protective role	25
observation period	25
three weeks	25
four weeks	25
cellular processes	25
next generation	25
infectious peritonitis	25
nucleotide polymorphisms	25
experimental animals	25
two months	25
lymphocyte count	25
patch test	25
groups according	25
cd positive	25
kg bw	25
late gestation	25
protein production	25
observational study	25
ab elisa	25
systematic review	25
human myometrial	25
reporter gene	25
patients may	25
pearson correlation	25
vitro model	25
young adults	25
chi square	25
au ml	25
old boy	25
cancer therapy	25
adult mice	25
cytokine profile	25
porcine circovirus	25
cells cultured	25
remained unchanged	25
patients died	25
also positive	25
adult horses	25
degradation products	25
high concentration	25
minute virus	25
anaplasma phagocytophilum	25
active site	25
mammalian cells	25
urea dissociation	24
breda virus	24
immune function	24
developed elisa	24
equal volume	24
organ injury	24
screening test	24
clinically ill	24
two dogs	24
three months	24
different methods	24
asthmatic children	24
trophoblast cell	24
ev numbers	24
cells play	24
direct detection	24
microvascular endothelial	24
graphpad prism	24
study also	24
embryo transfer	24
lipid metabolism	24
might also	24
carcinoma cells	24
posted june	24
rrna gene	24
correlated well	24
mrna level	24
cells also	24
high molecular	24
immune complexes	24
mitral valve	24
mdck pf	24
patients using	24
influenza season	24
surface receptors	24
arteritis virus	24
stress conditions	24
common elisa	24
incubated overnight	24
nitrocellulose membrane	24
intranasal administration	24
exchange chromatography	24
patients underwent	24
chronic obstructive	24
cytotoxic effects	24
cell numbers	24
particles ml	24
pediatric patients	24
concentration range	24
two doses	24
cell index	24
obtained results	24
controlled trial	24
membrane vesicles	24
remains unknown	24
idexx elisa	24
south africa	24
copy number	24
bacterial pathogens	24
vero cell	24
clinical outcomes	24
provide new	24
induced cytokine	24
two times	24
obstetrics gynecology	24
reference range	24
studied using	24
diffusion method	24
encephalomyelitis virus	24
glioma cells	24
allergic airway	24
magnetic beads	24
equine arteritis	24
positive blood	24
levels may	24
reading frame	24
may therefore	24
five different	24
tissue sections	24
positive cases	24
elevated serum	24
total body	24
cell biology	24
simplex virus	24
pandemic vaccine	24
persistent infection	24
decreased expression	24
asthma medication	24
swine serum	24
listeria monocytogenes	24
bicarbonate buffer	24
among different	24
purified virus	24
conserved among	24
rna virus	24
glucose uptake	24
lps challenge	24
laboratory diagnosis	24
inflammatory reaction	24
dna polymerase	24
patients infected	24
induced il	24
adoptive transfer	24
different times	24
national institutes	24
severe cases	24
inflammatory reactions	24
ae sd	24
sera samples	24
group consisted	24
mean od	24
specific igm	24
inhibitory activity	24
embryonated chicken	24
san diego	24
severe allergic	24
ligand binding	24
cross reactivity	24
cell interactions	24
computed tomography	24
azelastine nasal	24
higher rate	23
great potential	23
many patients	23
fruit bats	23
newborn offspring	23
elevating virus	23
antibody concentrations	23
evs may	23
assess whether	23
induced activation	23
baseline values	23
peritoneal cavity	23
gene sequence	23
incubation period	23
staphylococcal enterotoxin	23
energy metabolism	23
obstructive pulmonary	23
virus shedding	23
nasal polyps	23
cycle arrest	23
ae ae	23
serum level	23
bovine viral	23
biological activities	23
test samples	23
low concentration	23
also examined	23
virus titers	23
immunodeficiency virus	23
toxoplasma gondii	23
body temperature	23
cultured human	23
fetal lung	23
canine parvovirus	23
diseases including	23
high expression	23
gnrh ii	23
recently identified	23
school closure	23
complement activation	23
binding capacity	23
hr post	23
immunohistochemical analysis	23
scoring system	23
dependent increase	23
paraffin embedded	23
negative sepsis	23
polyethylene glycol	23
cd high	23
two independent	23
rna polymerase	23
urgent need	23
feline infectious	23
quantitative analysis	23
examined using	23
nude mice	23
laboratory animals	23
postoperative day	23
five times	23
squamous cell	23
nasal discharge	23
allowed us	23
shear stress	23
every hours	23
highly immunogenic	23
chicken egg	23
important factor	23
specific pathogen	23
sepsis syndrome	23
results provide	23
extracted using	23
cells derived	23
actin cytoskeleton	23
first line	23
alveolar macrophages	23
least days	23
igg igm	23
within one	23
neurodegenerative diseases	23
found positive	23
one group	23
last decade	23
eight patients	23
blood lymphocytes	23
marrow derived	23
laboratory findings	23
many diseases	23
fluid samples	23
thromboplastin time	23
matrix metalloproteinase	23
genetic diversity	23
using spss	23
protein assay	23
ige antibodies	23
purified sars	23
acid changes	23
antithrombin iii	23
vein thrombosis	23
two strains	23
mean arterial	23
one month	23
hours following	23
nasal mucosa	23
exosomes isolated	23
bovine coronavirus	23
natural history	23
placental tissue	23
recently demonstrated	23
nasal washes	23
cells transfected	23
mm edta	23
immunodeficient mice	23
factor alpha	23
rhinitis symptoms	23
pedv antibodies	23
virus vaccine	23
reference ranges	23
liver failure	23
patients aged	23
high yield	23
cell transplantation	23
sequence identity	23
antibacterial activity	23
viral pathogens	23
consecutive patients	23
dairy products	23
st cells	23
spike polypeptide	23
aea levels	23
lps injection	23
hearing loss	23
coli bl	23
avium subsp	23
will allow	23
antimicrobial therapy	23
patients developed	23
showed increased	23
assay sensitivity	23
helicobacter pylori	22
technical assistance	22
molecular epidemiology	22
analysis demonstrated	22
study aims	22
mhc i	22
vaccine candidate	22
reproductive tract	22
persistent pulmonary	22
agar plates	22
related viruses	22
detection method	22
coagulation parameters	22
previously identified	22
expressed proteins	22
associated proteins	22
single ev	22
blocking solution	22
laboratory data	22
derived ev	22
also confirmed	22
active metabolite	22
reduced expression	22
neutralizing activity	22
conventional elisa	22
ae ng	22
derived macrophages	22
specific antigen	22
pedv specific	22
intraperitoneal injection	22
versus ae	22
transplant recipients	22
length polymorphism	22
recently described	22
checkerboard titration	22
monoclonal anti	22
solid phase	22
image analysis	22
agarose gel	22
diagnostic laboratories	22
developing countries	22
sensor surface	22
biomarker analyzer	22
monocytes macrophages	22
constitutively expressed	22
fluorescence intensity	22
antigen specific	22
south korea	22
coagulation factors	22
patient serum	22
antioxidant activity	22
foxn nu	22
highly correlated	22
reuse allowed	22
soluble non	22
elisa antibody	22
microplate reader	22
also seen	22
surface antigen	22
disease diagnosis	22
rna isolation	22
i ifn	22
medium containing	22
liver tissue	22
well understood	22
mice using	22
vaccine strains	22
test result	22
substrate solution	22
experimental conditions	22
cytotoxic activity	22
also able	22
clinical microbiology	22
dodecyl sulfate	22
days following	22
cd foxp	22
studies demonstrated	22
calibration curve	22
mice immunized	22
iga antibodies	22
positive rate	22
test serum	22
differ significantly	22
statistically significantly	22
much lower	22
allowed without	22
ev preparations	22
blood sampling	22
fluorescent protein	22
endothelial dysfunction	22
small rnas	22
inactivated vaccine	22
xanthine oxidase	22
mean duration	22
fluorescent antibody	22
lactation period	22
patient developed	22
ev protein	22
circulating antibodies	22
high resolution	22
inflammatory markers	22
normal values	22
electron microscope	22
cd ratio	22
blood coagulation	22
household contacts	22
humoral immunity	22
serum tt	22
der patienten	22
study indicates	22
imi cis	22
patient presented	22
igm antibody	22
based methods	22
hospital stay	22
normal levels	22
tree pollen	22
strongly suggest	22
data provide	22
blot assay	22
liver function	22
active form	22
virus disease	22
na genes	22
without permission	22
marked increase	22
total cholesterol	22
cell membranes	22
fold serial	22
left atrial	22
bartonella spp	22
cells grown	22
sequence data	22
target antigen	22
normal limits	22
ad patients	22
alveolar epithelial	22
lamina propria	22
kg iv	21
collagen type	21
insulin levels	21
intravenous administration	21
group showed	21
rank test	21
study suggest	21
macrophage activation	21
corona diferencial	21
preliminary study	21
primary outcome	21
differed significantly	21
isolation rate	21
respiratory failure	21
household transmission	21
despite enhanced	21
ev proteins	21
low prevalence	21
ev surface	21
ingezim corona	21
protective immune	21
healthy women	21
regression models	21
expressing cd	21
tumour progression	21
signal peptide	21
immune regulation	21
sublingual immunotherapy	21
secondary bacterial	21
throughout pregnancy	21
using real	21
acid use	21
ii score	21
test performance	21
gene transcription	21
cell degranulation	21
hi test	21
human population	21
biological function	21
antigenic drift	21
dna sequence	21
health research	21
results support	21
specific anti	21
whole body	21
present data	21
internal genes	21
selective cox	21
different groups	21
experimental group	21
uterine emg	21
adverse event	21
neutralising mabs	21
cells stimulated	21
cell mediated	21
antibiotic susceptibility	21
neuronal cells	21
complement fixation	21
pregnant mice	21
higher expression	21
female balb	21
human health	21
surface proteins	21
transduction pathways	21
healthy horses	21
tgev strain	21
will also	21
mechanical ventilation	21
protein kinases	21
blood results	21
time reverse	21
well defined	21
vitro stimulation	21
cell counts	21
cecal ligation	21
similar pattern	21
chronic kidney	21
slightly lower	21
rt pcr	21
therapeutic effects	21
regenerative medicine	21
per week	21
following incubation	21
inhibition elisa	21
sendai virus	21
potential target	21
microarray analysis	21
capillary blood	21
slightly higher	21
using quantitative	21
vice versa	21
polycystic ovary	21
disease caused	21
soluble fibrin	21
human seasonal	21
tests showed	21
patients presented	21
first day	21
virus neutralizing	21
high frequency	21
molecular techniques	21