bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram frequency
dengue virus826
virus infection294
denv infection289
zika virus185
viral rna177
west nile141
infected cells129
dengue fever124
antiviral activity121
nile virus115
chikungunya virus114
virus replication113
hemorrhagic fever111
viral replication104
dengue viruses102
vero cells102
dengue hemorrhagic98
dengue infection96
public health92
aedes aegypti89
immune response89
virus type84
encephalitis virus76
viral infection71
zikv infection70
denv replication70
yellow fever70
denv serotypes67
immune responses61
japanese encephalitis60
nucleic acid58
rna replication57
pcr assay56
neutralizing antibodies56
dengue vaccine56
reverse transcription55
isothermal amplification55
severe dengue54
host cells53
host factors53
cell lines53
dependent enhancement52
infectious diseases52
time rt51
cell line51
rna viruses50
cord uid50
aedes albopictus50
doc id50
innate immune50
porcupine dates49
respiratory syndrome48
disease severity48
cell culture48
years old48
blood donors48
vector control47
amino acid47
host cell47
denv ns46
nonstructural protein45
four denv45
replication complex45
fever virus45
envelope protein45
dengue disease44
virus infections44
nlrp inflammasome44
denv rna44
inflammasome activation44
fubc protein44
mediated isothermal43
shock syndrome43
inhibitory factor43
dendritic cells43
type i42
rna synthesis41
lamp assay41
structural proteins40
macrophage migration40
dengue infections40
pcr system40
hela cells39
endoplasmic reticulum39
migration inhibitory38
mosquito cells38
performed using38
vascular leakage38
virus serotype38
viral infections38
risk factors38
influenza virus37
dengue shock37
mg ml37
rna virus36
clinical manifestations36
acute respiratory36
denv infections36
binding protein35
virus particles35
rapid detection35
viral protein35
severe acute34
eid agents34
puerto rico33
virus ns33
infectious disease33
ns protein33
phylogenetic analysis33
membrane vesicles33
immune complexes33
previously described33
monoclonal antibodies33
antiviral effect33
flavivirus infections32
virus entry32
denv rt32
monoclonal antibody32
time pcr32
guangdong province32
mass spectrometry32
four serotypes32
dengue type31
clinical samples31
health organization31
well plates31
denv serotype31
cell death31
viral genome31
structural protein30
syndrome coronavirus30
virus transmission30
genotype i30
world health30
membrane fusion30
chain reaction29
based assay29
ns antigen29
sybr green29
ea fraction29
mammalian cells29
endothelial cells29
febrile illness29
borne encephalitis28
human immunodeficiency28
immunodeficiency virus28
dengue viral28
dengue cases28
herpes simplex28
complement activation28
polymerase chain28
pfu ml28
real time28
antibody response28
life cycle27
rna binding27
serum samples27
united states27
domain iii27
mif secretion27
type virus27
ag mice27
gene expression27
severe disease26
protein expression26
infectious virus26
nonstructural proteins26
may also26
flavivirus infection26
dhf dss26
post infection26
viral proteins26
stranded rna25
cells treated25
virus nonstructural25
endemic areas25
days post25
cells infected25
dengue patients25
borne viral25
peripheral blood25
fusion loop24
rna interference24
ns gene24
virus titer24
virus serotypes24
electrode surface24
molecular evolution24
simplex virus24
viral particles24
fully automated23
infected patients23
highly conserved23
induced autophagy23
pregnant women22
acute phase22
inhibitory effect22
room temperature22
severe cases22
rna polymerase22
high mannose22
tetravalent dengue22
ns protease22
virus rna22
protein ns22
taken together22
virucidal activity22
adaptive immune22
results showed22
statistically significant21
aedes mosquitoes21
igg antibodies21
dengue haemorrhagic21
global distribution21
reporter system21
southeast asia21
present study21
haemorrhagic fever21
treated cells21
vaccine development21
viral load21
first time21
antiviral activities21
hepg cells21
impedance signal21
replication complexes20
severe fever20
virus envelope20
chikv infection20
family flaviviridae20
amino acids20
neutralizing antibody20
dependent manner20
respiratory syncytial20
zika fever20
cell surface20
life technologies20
innate immunity20
denv igm20
results suggest20
residual spraying20
indoor residual20
virus production20
disease control20
positive selection19
severe denv19
envelope glycoprotein19
reduction neutralization19
human monocytes19
high levels19
quantitative rt19
middle east19
authors declare19
selection pressure19
measles virus19
binding proteins19
blood safety19
arboviral diseases19
membrane rearrangements19
rna genome19
reporter systems19
cells transfected19
automated pcr19
clinical trials19
french polynesia19
blood samples19
plaque assay19
strand rna19
chikungunya fever19
sample size19
solomon islands19
animal models18
recombinant fubc18
western blotting18
open reading18
reporter gene18
heart diseases18
thrombocytopenia syndrome18
human serum18
time reverse18
semliki forest18
syncytial virus18
different genotypes18
new guinea18
clinical trial18
samples collected18
phylogenetic tree18
serially diluted18
systematic review18
hcv infection18
cell monolayers18
immune system18
dependent rna18
electron microscopy18
analysis using18
capsid protein18
control measures18
live attenuated17
lipid droplets17
immune cells17
clinical diagnosis17
denv transmission17
bovine serum17
wnv infection17
per year17
mm cbx17
acute febrile17
secondary denv17
cell responses17
denv particles17
folic acid17
plaque reduction17
domain ii17
plasma membrane17
significantly decreased17
dengue outbreak17
genus flavivirus17
age group17
reverse transcriptase17
different concentrations17
dengue epidemics17
early clinical17
copies reaction17
replication factories17
reading frame17
cell viability17
flaviviridae family16
virus attachment16
sars coronavirus16
virus vaccine16
indicated time16
another study16
forest virus16
virus strains16
higher proportion16
tannic acid16
progeny virions16
vertical transmission16
swine fever16
er stress16
serotype specific16
ns proteins16
described previously16
houttuynia cordata16
human mobility16
cbx treatment16
various concentrations16
sindbis virus16
visceral leishmaniasis16
virus infectivity16
borne diseases16
disease virus16
aegypti mosquitoes15
determined using15
rna rna15
tannic acids15
global public15
acute dengue15
selective autophagy15
vesicular stomatitis15
viral disease15
mouse model15
age groups15
classical swine15
virus particle15
laboratory diagnosis15
significantly higher15
closely related15
antigen presentation15
tissue culture15
clinical symptoms15
primary human15
antiviral drugs15
time points15
fusion protein15
culture medium15
endemic area15
specific rt15
secretory pathway15
rna copies15
cytokine storm15
agarose gel15
membrane structures15
flow cytometry15
ms identified15
important role15
nucleotide sequences15
stomatitis virus15
sri lanka15
recent study15
tropical medicine15
transcription loop15
infectious viral15
three structural15
prospective study15
east respiratory14
nervous system14
way anova14
plasma leakage14
dengue activity14
blood mononuclear14
neutralization test14
informed consent14
two different14
wnv kun14
south america14
also observed14
virus neutralization14
antiviral response14
molecular epidemiology14
denv diii14
several studies14
additional file14
reporter virus14
membranous replication14
maturation process14
diagnostic tests14
blood transfusion14
nets formation14
independent experiments14
mononuclear cells14
based reporter14
bc loop14
mouse models14
infected individuals14
dengue antibodies14
ifitm protein14
mosquito vectors14
negative control14
com scientificreports14
broadly neutralizing14
fetal bovine14
mosquito control14
endemic countries14
cellular proteins14
human monoclonal14
genotype ii14
replication cycle14
linked immunosorbent14
automated pockit13
neutrophil extracellular13
vascular permeability13
immunosorbent assay13
risk factor13
control group13
latin america13
virucidal effect13
forming assay13
syndrome virus13
recent studies13
methanol crude13
gel electrophoresis13
pockit central13
lateral flow13
membrane protein13
untranslated region13
previous study13
ns ag13
clinical features13
antiviral drug13
genotype iii13
maximum likelihood13
statistical analysis13
emerging infectious13
subtropical regions13
ns serotype13
measured using13
four dengue13
clinical management13
neutralizing activity13
i ifn13
type ii13
selected studies13
chronic comorbidities13
denv envelope13
reporter protein13
recent years13
study demonstrated13
infection enhancement13
crucial role13
complement receptor13
chinese blood13
antibody responses13
cdc real12
hr post12
human macrophages12
infected cell12
autochthonous dengue12
blood cells12
day post12
i i12
dengue severity12
uprt cells12
cell membranes12
dengue serotypes12
central nervous12
dengue ns12
prm protein12
phase i12
standard plaque12
plasma samples12
secondary infection12
simultaneous detection12
genome replication12
based biosensor12
clinical signs12
replication sites12
viral particle12
global health12
molecular evolutionary12
scorpion venom12
fever dengue12
spectrum antiviral12
enveloped viruses12
epidemiological data12
immune complex12
dengue vaccines12
may lead12
detect denv12
copy number12
secondary infections12
lipase activity12
vaccine candidates12
among blood12
pcr systems12
dengue serotype12
strains isolated12
denv genome12
positive control12
cell lysates12
denv induced12
huvec cells12
ifitm proteins12
antiviral effects12
mice infected12
virus detection12
billion people12
congenital zika12
suckling mice12
bhk cells12
autophagy machinery12
dna vaccine12
tertiary care12
two viral11
acid extraction11
amplification assay11
different lineages11
supplementary material11
immune evasion11
pcr assays11
exosomes derived11
csp bj11
serum specimens11
rapid spread11
insect cells11
signal response11
mtt assay11
health problem11
fisher scientific11
dengue envelope11
early stage11
antiviral therapy11
crude extracts11
control study11
virus outbreak11
molecular mechanisms11
viral amplification11
infection dengue11
infected patient11
zikv infections11
unfolded protein11
dengue pathogenesis11
also found11
specific antibodies11
mm tris11
clinical presentation11
abv illness11
ngc strain11
dates extracts11
denv activity11
culture supernatant11
sample preparation11
specific primers11
protein response11
clinical isolates11
creative commons11
recombinant protein11
dhf epidemics11
confirmed cases11
flavivirus diseases11
virus yield11
denv infected11
viral variants11
dengue vector11
subunit vaccine11
cytokine production11
mosaic virus11
inhibit denv11
i interferon11
small interfering11
competing interests11
afi cases11
molecular biology11
genotype iv11
general population11
detection limit11
serial dilutions11
accession number11
signaling pathways11
infection among11
rna helicase11
endothelial cell11
genomic rna11
two viruses11
target cells11
least two11
serotype denv11
virus adsorption11
mosquito cell11
neutralising antibodies11
intracellular pathogens10
viral envelope10
replication organelles10
dengue viremia10
case report10
blotting analysis10
fc receptor10
congenital anomalies10
secreted ns10
also used10
autophagy pathway10
severe clinical10
complement receptors10
disease burden10
mouth disease10
using denv10
small number10
virus genome10
weight loss10
based assays10
positive dengue10
er membranes10
viral entry10
neutralization assay10
deficient mice10
barr virus10
smp peptide10
infection may10
borne viruses10
mosquito vector10
well plate10
immunofluorescence assay10
secondary structure10
host factor10
endemic regions10
will occur10
results indicate10
host proteins10
infection induces10
cells using10
weeks old10
endogenous ifitm10
also reported10
antibodydependent enhancement10
future studies10
thermo fisher10
zika syndrome10
growth medium10
new insights10
virus strain10
hcv replication10
luciferase activity10
suspected cases10
rna levels10
acid sequence10
rna decay10
increased risk10
previous studies10
warning signs10
viral diseases10
host immune10
symptomatic abv10
cells via10
sequence alignment10
lipid metabolism10
er lumen10
clinical performance10
conserved regions10
gene sequences10
denv serotyping10
intradomestic controls10
glycosylation site10
congenital zikv10
host innate10
membrane alterations10
inflammatory cytokines10
green i10
previously shown10
abv infection10
autochthonous cases10
data showed10
determine whether10
active surveillance10
regression analysis10
abv transmission10
er membrane10
infection model10
epidemiological impact10
acute denv10
epithelial cells9
overlay medium9
urgently needed9
double membrane9
blood centers9
symptom onset9
severe forms9
blood meal9
dengue prevention9
dhf cases9
primary dengue9
secondary dengue9
denv strains9
ebola virus9
institutional review9
visualized using9
acid sequences9
rna copy9
whole blood9
protective immunity9
subgenomic replicon9
reported cases9
binding lectin9
cell entry9
feline infectious9
red blood9
assembly sites9
extracellular traps9
will also9
day pos9
trial will9
response pattern9
replicon rna9
online version9
medical university9
applied biosystems9
human dendritic9
uninfected cells9
global spread9
lamp product9
induced autophagosomes9
viral strains9
population controls9
recipient hela9
like receptor9
antiviral agent9
differential diagnosis9
ifitm expression9
class ii9
inflammatory response9
natural compounds9
evolutionary genetics9
washed twice9
per well9
borne disease9
transmission electron9
dengue transmission9
control sirna9
cohort study9
throughput screening9
copy numbers9
previously reported9
clinical outcomes9
vaccine candidate9
multiplex real9
infected mice9
findings suggest9
different denv9
crispr cas9
symptomatic cases9
analyzed using9
viremia titer9
controlled trial9
extracellular environment9
human cytomegalovirus9
poc pon9
wnv cases9
infectious peritonitis9
may contribute9
genotypes i9
dengue dengue9
potential risk9
clinical course9
infectious agents9
identified factors9
viral factors9
human complement9
stimulated genes9
dengue diagnosis9
borne flaviviruses9
incubation period9
epidemic potential9
antiviral immunity9
sequence diversity9
electron microscopic9
goat anti9
hours post9
progeny denv9
vaccinia virus9
sanofi pasteur9
denv host9
eye pain9
commercially available9
human disease9
effective antiviral9
fubc gene9
viral replicase9
emory university9
containing exosomes9
serotype correlate9
inhibitory concentration9
innate antiviral9
obtained using9
medium containing9
graphpad prism9
se asia9
mammalian cell9
american journal9
yucatan state9
i clinical9
denv amplification9
human immune8
publication bias8
protein band8
among patients8
mif rna8
pcr using8
denv igg8
pockit combo8
persistent infection8
enhancing antibodies8
vero cell8
negative controls8
affinity maturation8
highest concentration8
igg antibody8
inhibits denv8
total rna8
zikv rna8
pr peptide8
bone marrow8
prevalence rate8
positive samples8
cellular immune8
cell type8
study reported8
mif transcription8
single open8
geographic distribution8
humoral immune8
antibody dependent8
chronic disease8
mortality rate8
crystal structure8
albopictus mosquitoes8
virus disease8
rna extraction8
drug development8
ros production8
serine protease8
human diseases8
like illness8
encephalomyocarditis virus8
proteins ns8
estimated million8
niclosamide treatment8
western blot8
cases reported8
phylogenetic trees8
dna vaccines8
viral protease8
different serotypes8
transcription factors8
southern france8
envelope domain8
virus life8
igg titer8
post transfection8
induces autophagy8
data analysis8
two independent8
carbon electrode8
foci forming8
urban areas8
mononuclear phagocytes8
million people8
calculated using8
imported cases8
stimulated gene8
protease activity8
impedimetric cell8
using reverse8
santa cruz8
positive cells8
pcr amplification8
core protein8
significant reduction8
igm elisa8
recipient cells8
critical review8
virus isolation8
antiviral agents8
coding region8
oxidative stress8
denv cases8
heparan sulfate8
cell cultures8
early stages8
phase ii8
significantly reduced8
induced membrane8
low levels8
severe form8
standard curve8
analysis showed8
yap island8
cell immunity8
complement system8
critical role8
golgi apparatus8
viral titers8
statistical analyses8
biological control8
high sensitivity8
brucella spp8
large outbreak8
fold serial8
step rt8
review board8
diabetes mellitus8
control groups8
three times8
antiviral efficacy8
buffered saline8
nonhuman primates8
dengue illness8
inflammatory responses8
national university8
sense rna8
antiviral compounds8
care hospital8
complex glycans8
equal volume8
insulated isothermal8
commons attribution8
lethal infection8
virus infected8
participants years8
vicenza province8
laboratory testing8
abdominal pain8
type lectin8
infectious denv8
single dose8
known denv8
study participants8
chronic diseases8
high throughput8
virus titers8
many viruses8
recorded waypoints8
dengue endemic8
viruses using8
intracellular viral8
humidified incubator8
disease outcome8
virus inhibition8
mosquito species8
tcid assay8
till hr8
i ii7
expression vector7
mosquito bites7
protective efficacy7
epidemic arboviral7
geographical distribution7
study found7
specific virus7
late stage7
igg immune7
rhesus monkeys7
final concentration7
pcr reactions7
measles vaccine7
rapid diagnostic7
glycosylation sites7
continuous treatment7
cinanserin hydrochloride7
infected human7
mosquito breeding7
reaction denv7
culture supernatants7
ii ifn7
genotype database7
similar clinical7
transfusion risk7
polypyrimidine tract7
endothelial permeability7
also showed7
rubella virus7
south korea7
denv outbreaks7
combo system7
viral titer7
currently available7
recombinant virus7
graphpad software7
human skin7
integral membrane7
denv protein7
crude venom7
elevated levels7
abv cases7
enhances virus7
forming units7
dengue epidemic7
joint pain7
nucleic acids7
four days7
febrile illnesses7
hcv activity7
disease outbreak7
causes dengue7
natural products7
crystal violet7
limited settings7
rnai pathway7
family members7
potential therapeutic7
small sample7
viral translation7
structural basis7
transmission cycle7
central role7
flavivirus kunjin7
cellular rna7
viral life7
ns hexamer7
disease prevention7
ifn production7
induced cytopathogenesis7
significant difference7
infected vero7
southern china7
health care7
cycle sequencing7
indirect immunofluorescence7
human igg7
article distributed7
inflammatory macrophages7
coronavirus replication7
zikv particles7
global burden7
takes place7
secondary antibody7
mouse igg7
bc peptides7
hcv rna7
two types7
arbovirus infection7
newly synthesized7
ko cells7
multiplex rt7
interfering rna7
human blood7
experimental design7
mosquito populations7
renilla luciferase7
laboratory confirmation7
novel reporter7
viral foci7
disease pathogenesis7
denv antibodies7
human population7
mediated endocytosis7
specific antiviral7
extracellular milieu7
clinical characteristics7
exclude concomitant7
final manuscript7
blood donation7
derived macrophages7
hepatitis virus7
incubated overnight7
mediated enhancement7
mouse monoclonal7
ifn receptor7
enhance dengue7
epidemic areas7
pacific region7
induce autophagy7
protects mice7
time spent7
cleavage site7
fold reduction7
chikungunya viruses7
sialic acid7
virion surface7
hek cells7
complex formation7
neurological complications7
associated protein7
global threat7
virus neutralizing7
rna polymerases7
randomized controlled7
bl mice7
genetics analysis7
pcr amplicons7
pcr products7
hcv ns7
ns region7
care diagnostics7
ade infection7
different stages7
will provide7
breast milk7
selection pressures7
endosomal acidification7
concomitant infections7
four antigenically7
dimensional architecture7
high resolution7
widely used7
south pacific7
virus replicon7
different cell7
following infection7
mini kit7
high level7
specific detection7
single strand7
disease outbreaks7
antibody titers7
induced inflammasome7
authors read7
virus output7
early diagnosis7
phylogenetic relationships7
antigenic sin7
polyprotein processing7
chikv infections7
insecticide resistance7
fatty acid7
isothermal pcr7
protein interactions7
vero slam7
human peripheral7
interests include7
first year7
endothelial glycocalyx7
scientificreports www7
human movement7
denv may7
mediated neutralization7
flavivirus ns7
vascular leak7
surveillance system7
plaque forming7
autophagosome formation7
ns rt7
antiviral responses7
prevalence rates7
pbs buffer7
written informed7
seven nonstructural7
cd spectrum7
study also7
including denv7
wide range7
molecular weight7
denv viral7
autophagic vesicles7
original antigenic7
patients may7
least three7
denv life7
cells per7
expressing cells7
children aged7
analysis revealed7
receptor type7
whole cell7
sirnas targeting7
luciferase gene7
orv illness7
genomic sequences7
mhc class7
th day6
human cells6
may play6
zikv transmission6
molecular diagnosis6
fluorescent protein6
central system6
virus subgenomic6
sirna transfection6
live denv6
epidemiological characteristics6
cell activation6
viremic patients6
four different6
autophagosomal membranes6
assay showed6
genbank af6
depth analysis6
beet yellows6
golgi network6
clinical specimens6
linear correlation6
cytotoxic effects6
similar results6
proteasome pathway6
blood products6
less conserved6
selectivity index6
cruz biotechnology6
human antibodies6
protein production6
denv outbreak6
like particles6
virus molecular6
borne transmission6
asian genotype6
clinical isolate6
zikv epidemic6
highly specific6
nonspecific amplification6
essential medium6
containing exosome6
access article6
proinflammatory cytokines6
seven non6
terminal complement6
evans blue6
leishmania major6
igg elisa6
potent antiviral6
serotypes denv6
female mice6
east africa6
rna molecules6
slam cells6
targeted indoor6
sequence analysis6
reactive antibodies6
national center6
recombinant dengue6
presenting cells6
virus using6
small rna6
viral antigens6
using primers6
type envelope6
human herpesvirus6
medical research6
perinatal transmission6
emerging viruses6
mobility patterns6
nm diameter6
denv replicates6
protease cleavage6
nonstructural glycoprotein6
envelope proteins6
sars cov6
may explain6
essential role6
study protocol6
viral loads6
aedes spp6
vast majority6
seven days6
reporter cell6
post transfusion6
membrane compartments6
accession numbers6
flavivirus genus6
co choco6
denv production6
rna samples6
cell fitness6
abv case6
monoclonal anti6
wnv replication6
rna processing6
case definitions6
coronavirus disease6
molecular characterization6
ade assay6
anti denv6
broad spectrum6
signal transduction6
intracellular pools6
residual insecticides6
cerebrospinal fluid6
multiple comparison6
disulfide bonds6
specific anti6
soluble protein6
patients presenting6
conjugated goat6
heterogeneous nuclear6
inhibits dengue6
enveloped virus6
newly developed6
cells dengue6
imported dengue6
green iebased6
equine encephalitis6
one study6
infected mosquitoes6
automated sample6
rna detection6
rna translation6
dhf epidemic6
papua new6
hela uprt6
hamster kidney6
increased viral6
highly immunogenic6
serological tests6
denv induces6
denv patients6
homology search6
brain barrier6
chikv vaccine6
molecular clock6
protein gene6
factors may6
specific monoclonal6
receptor binding6
fatty acids6
vertebrate hosts6
natural killer6
louis encephalitis6
murray valley6
reduce dengue6
ifn signaling6
brazil zika6
genetic diversity6
denv genotype6
ms ms6
automated system6
bc loops6
first week6
strain isolated6
possible association6
tight junctions6
selected based6
reverse primer6
replicon cells6
mutant viruses6
infected aedes6
san diego6
patients infected6
viral ns6
master mix6
gene transcription6
lamp reaction6
kindly provided6
global spatial6
cell membrane6
sequence identity6
ribosome entry6
results demonstrated6
two major6
late stages6
protein domain6
commonly used6
sample collection6
enhance viral6
entry site6
mycobacterium tuberculosis6
new england6
transmission season6
fc receptors6
million dengue6
human parvovirus6
linked glycosylation6
inner mongolia6
denv diiis6
proteomic analysis6
medium supplemented6
glycoprotein ns6
including dengue6
possible role6
million cases6
cbx inhibits6
disease progression6
local health6
internal ribosome6
mean age6
microplate reader6
mouse hepatitis6
acid binding6
also tested6
leukemia virus6
also demonstrated6
neutralizing monoclonal6
centralized location6
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