bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
bcg vaccination	747
trained immunity	309
bcg vaccine	272
immune response	197
bacillus calmette	161
universal bcg	151
innate immune	142
immune responses	132
vaccination policy	126
clinical trials	118
mycobacterium tuberculosis	113
immune system	112
per million	108
bacille calmette	102
bladder cancer	102
author funder	99
copyright holder	99
granted medrxiv	99
respiratory syndrome	95
version posted	94
acute respiratory	92
coronavirus disease	84
made available	82
international license	77
mycobacterium bovis	74
severe acute	72
protective effect	70
dendritic cells	62
doc id	61
cord uid	61
syndrome coronavirus	61
lymph nodes	60
immune cells	60
bovis bcg	60
respiratory tract	58
viral infections	58
infectious diseases	58
vaccination policies	58
world health	57
million population	57
innate immunity	54
health organization	53
medrxiv preprint	52
novel coronavirus	51
peer review	50
cell responses	50
systematic review	48
cytokine production	48
severe covid	48
income countries	48
vaccine development	47
mortality rate	46
deaths per	46
health care	45
primary immunodeficiency	45
live attenuated	45
mortality rates	44
bcg coverage	43
bone marrow	43
risk factors	43
gene expression	43
viral infection	41
specific effects	41
inflammatory response	41
induced trained	41
randomized controlled	41
autoimmune diseases	39
total number	38
salmonella enterica	38
clinical trial	38
attenuated salmonella	37
age group	37
inflammatory cytokines	37
tract infections	37
listeria monocytogenes	36
posted may	36
adverse events	36
bcg strains	36
adaptive immune	35
respiratory infections	35
bcg immunization	35
national bcg	35
enterica serovar	34
leprosy patients	34
statistically significant	33
protective immunity	33
years old	33
controlled trial	33
side effects	33
influenza vaccination	33
lymph node	33
epithelial cells	33
bcg administration	32
cases per	32
mg dl	32
virus infection	32
influenza virus	32
united states	32
posted june	31
immunodeficiency virus	31
vaccination coverage	30
south africa	30
combined immunodeficiency	30
epidemiological study	29
cervical lymph	29
nk cells	29
cvid patients	29
controlled trials	29
public health	29
cd cd	29
bcg policy	29
median age	29
increased risk	29
immune memory	29
statistical significance	28
escherichia coli	28
middle east	28
vaccine candidate	28
disease severity	27
tuberculosis infection	27
reduced morbidity	27
helicobacter pylori	27
yellow fever	27
prostate cancer	27
different countries	27
population size	27
intravesical bcg	27
bcg infection	27
antibody responses	26
per capita	26
table i	26
case fatality	26
cohort study	26
human immunodeficiency	26
rights reserved	25
vaccine coverage	25
fatality rate	25
respiratory syncytial	25
guinea pigs	25
flow cytometry	25
bovine lactoferrin	25
tuberculosis vaccine	25
dna vaccine	25
recent study	25
linear regression	25
regression discontinuity	25
syncytial virus	25
coronavirus infection	24
randomized clinical	24
upper respiratory	24
neutralizing antibodies	24
protective effects	24
sars coronavirus	24
primary immunodeficiencies	23
vaccine strains	23
vaccine candidates	23
severe combined	23
high risk	23
million inhabitants	23
nonspecific effects	23
specific cd	23
vaccine efficacy	23
epigenetic reprogramming	22
hematopoietic stem	22
exposure prophylaxis	22
kawasaki disease	22
mediated immunity	22
serovar typhimurium	22
world atlas	22
cell carcinoma	22
born just	22
significantly lower	22
bcg world	22
recombinant bcg	22
care workers	22
leprosy control	22
east respiratory	22
global bcg	22
pid patients	21
household contacts	21
vaccination status	21
tca cycle	21
family history	21
peripheral blood	21
single dose	21
salmonella typhimurium	21
invasive bladder	21
production capacity	21
healthcare workers	21
chronic granulomatous	21
age groups	21
adult patients	20
million people	20
animal models	20
memory cd	20
th th	20
mouse model	20
ex vivo	20
intensive care	20
natural killer	20
antibody response	20
human monocytes	20
alveolar macrophages	20
bcg reactivation	20
bcg vaccines	20
vaccination protects	20
infectious disease	20
high levels	20
cell immunity	20
granulomatous disease	20
th responses	20
cell surface	19
experimental viral	19
bcg countries	19
mediated immune	19
urothelial carcinoma	19
factors associated	19
autoimmune disease	19
case report	19
related complications	19
past years	19
two groups	19
stem cell	19
inflammatory responses	19
presenting cells	19
vaccine vector	19
cytokine expression	19
per inhabitants	19
among patients	19
spike protein	18
cancer patients	18
recurrent infections	18
vaccine strain	18
previous studies	18
based vaccines	18
vaccination program	18
replacement therapy	18
metabolic pathways	18
like receptor	18
adherent cells	18
three months	18
available data	18
trained innate	18
rheumatoid arthritis	18
cohorts born	18
across countries	17
cytokines associated	17
superficial bladder	17
clinical features	17
cytokine storm	17
may also	17
mice infected	17
immune reconstitution	17
class ii	17
severe disease	17
antibody deficiency	17
protein kinase	17
dna vaccines	17
lupus erythematosus	17
important role	17
human lactoferrin	17
protective efficacy	17
infectious agents	17
cd cells	17
renal cell	17
viral load	17
data suggest	17
fatality rates	17
healthy volunteers	17
clinical characteristics	17
bacterial vectors	17
murine model	17
influenza vaccine	17
lower respiratory	16
social distancing	16
many countries	16
nonspecific protection	16
clinical immunology	16
infected cells	16
systemic lupus	16
even though	16
randomised controlled	16
disseminated bcg	16
standard deviation	16
amino acid	16
binding domain	16
vaccination programs	16
physical examination	16
lower mortality	16
confounding factors	16
cell types	16
vaccine antigens	16
total population	16
high prevalence	16
fatty acid	16
antiviral activity	16
population density	16
inflammatory syndrome	16
randomized trial	16
first year	16
environmental factors	16
necrosis factor	16
secretion system	15
high income	15
inoculation site	15
reported cases	15
host cells	15
bcg immunisation	15
nitric oxide	15
respiratory distress	15
antibody deficiencies	15
tissue damage	15
significant difference	15
molecular patterns	15
vaccinated subjects	15
convalescent plasma	15
mg ml	15
current universal	15
cell wall	15
bcg strain	15
authors declare	15
adaptive immunity	15
bacterial infections	15
mycobacterial infection	15
immunodeficiency diseases	14
medical history	14
one study	14
cardiovascular disease	14
european countries	14
health system	14
immune cell	14
nan doi	14
cell activation	14
virulence factors	14
bcg inoculation	14
higher mortality	14
without permission	14
scid patients	14
cell transplantation	14
healthy individuals	14
recent bcg	14
attributable mortality	14
candida albicans	14
ecological studies	14
causal reasoning	14
childhood vaccination	14
autosomal recessive	14
african countries	14
cell populations	14
statistical analysis	14
immunity effects	14
epigenetic changes	14
dose rifampicin	14
stem cells	14
common variable	14
case reports	14
cell function	14
neutralizing antibody	14
risk disease	14
confidence interval	14
associated molecular	14
vaccination rate	14
bcg induced	14
new york	14
allowed without	14
reuse allowed	14
risk factor	14
node cells	14
based vaccine	14
study showed	14
gov identifier	14
lung injury	13
old boy	13
new coronavirus	13
bcg induces	13
distress syndrome	13
mortality per	13
rhesus macaques	13
received bcg	13
cell cultures	13
time point	13
bcg vaccinated	13
hiv infection	13
correlation hypothesis	13
clinical manifestations	13
oral vaccine	13
attenuated vaccine	13
recombinant human	13
hbv vaccine	13
mm nacl	13
specific memory	13
present study	13
beneficial effects	13
lasting effects	13
heat killed	13
like receptors	13
young adults	13
ivig therapy	13
past medical	13
six months	13
reduced covid	13
attenuated strain	13
world bank	13
antigen presentation	13
tb prevalence	13
publicly available	13
higher risk	13
highly significant	13
tract infection	13
older individuals	13
antigen presenting	13
clinical studies	13
severe infections	13
bcg may	13
vaccine design	13
phase iii	13
post vaccination	13
omenn syndrome	13
new leprosy	13
epidemiological studies	12
vaccination may	12
case detection	12
subunit vaccines	12
young age	12
alignment date	12
com scientificreports	12
cov infection	12
patients diagnosed	12
measles virus	12
posted september	12
bcg mimics	12
old girl	12
salmonella typhi	12
tumor necrosis	12
university hospital	12
time points	12
antiretroviral therapy	12
adverse reactions	12
confidence intervals	12
cytokine responses	12
marrow transplantation	12
two patients	12
tests per	12
mycobacterial disease	12
lactococcus lactis	12
igg subclass	12
several studies	12
salmonella vaccine	12
corynebacterium parvum	12
oral immunization	12
binding protein	12
whole blood	12
heat shock	12
lpep program	12
adverse effects	12
key hubs	12
increased production	12
streptococcus pneumoniae	12
patients receiving	12
diagnostic tests	12
offer protection	12
pilot study	12
disease progression	12
widely used	12
mg kg	12
control group	12
null hypothesis	12
protective role	12
lung tissue	12
global health	12
cell response	12
clinical outcomes	12
vaccine program	12
pseudomonas aeruginosa	12
colep study	12
humoral immune	12
patients treated	12
intravesical therapy	12
host defense	12
control study	12
type i	12
low income	12
genomic dna	12
performed using	12
neonatal period	12
calmette guerin	12
another study	12
connective tissue	11
reduced mortality	11
propionibacterium acnes	11
heterologous th	11
infections per	11
human papillomavirus	11
mm hepes	11
countries without	11
mm cacl	11
unrelated pathogens	11
confirmed cases	11
significant factors	11
trained immune	11
scatter plot	11
via epigenetic	11
mean age	11
current evidence	11
common logarithm	11
data analysis	11
significantly higher	11
negative correlation	11
ivig treatment	11
heterogeneous immunity	11
pulmonary disease	11
adherent fraction	11
april st	11
stimulation index	11
beneficial effect	11
strong correlation	11
acute upper	11
severe respiratory	11
metastatic renal	11
life expectancy	11
clinical presentation	11
dendritic cell	11
also found	11
vaccinia virus	11
observational studies	11
bcg revaccination	11
innate trained	11
variable immunodeficiency	11
bcg therapy	11
general population	11
indian population	11
laboratory findings	11
individuals born	11
syndrome induced	11
measles infection	11
tetanus toxoid	11
mycobacterial antigens	11
bcg expressing	11
significant differences	11
coverage rate	11
type immune	11
upper middle	11
attenuated bacterial	11
natural experiment	11
activated protein	11
class i	11
multiple sclerosis	11
fusion protein	11
dependent enhancement	10
multivariable analysis	10
patients hospitalized	10
chronic inflammatory	10
locally advanced	10
reinfection via	10
lg ml	10
bovis bacillus	10
biochemical recurrence	10
cancer immunotherapy	10
live bcg	10
developing countries	10
different strains	10
year follow	10
cell counts	10
radical prostatectomy	10
whose equation	10
non specific	10
vaccine safety	10
months post	10
middle age	10
hospitalized patients	10
adjuvant effect	10
serovar typhi	10
environmental mycobacteria	10
kidney cancer	10
disease burden	10
protective action	10
new vaccine	10
inflammatory cytokine	10
progenitor cells	10
lung disease	10
studies suggest	10
care unit	10
asia syndrome	10
significant association	10
closely related	10
vaccination enhances	10
tract urothelial	10
acid synthesis	10
critical role	10
seasonal influenza	10
may lead	10
clinical course	10
infected individuals	10
early stages	10
protective immune	10
heterologous effects	10
urgent need	10
immunological memory	10
model whose	10
regression model	10
first time	10
virus type	10
human coronaviruses	10
vaccine delivery	10
regression analysis	10
mass bcg	10
growth factor	10
knockout mutants	10
phase clinical	10
limited number	10
herpes simplex	10
high level	10
ebola virus	10
one year	10
di george	10
immune function	10
last years	10
vaccine vectors	10
tb vaccine	10
mhc class	10
mycobacterial infections	10
described previously	10
converting enzyme	10
active cases	10
viral replication	10
hiv vaccine	10
modified vaccinia	10
new cases	10
determine whether	9
spike glycoprotein	9
suppressor cells	9
discontinuity design	9
mucosal immune	9
oral administration	9
whether bcg	9
heterologous pathogens	9
highly attenuated	9
family members	9
coronavirus vaccines	9
contact tracing	9
induce trained	9
beneficial nonspecific	9
considering bcg	9
cell lines	9
survival outcomes	9
human immune	9
host immune	9
recognition receptors	9
attenuated vaccines	9
mycobacterium leprae	9
bcg use	9
death reports	9
based case	9
acute lung	9
patients showed	9
dependent nonspecific	9
recurrent respiratory	9
narrative review	9
discontinuity designs	9
serine protease	9
positive effect	9
binding site	9
th response	9
diabetes mellitus	9
genetic analysis	9
viral vector	9
unvaccinated young	9
significant associations	9
positive correlation	9
active surveillance	9
bcg vaccinations	9
also known	9
contact screening	9
using bcg	9
birth cohorts	9
mmr vaccine	9
analysis revealed	9
celiac disease	9
leprosy prevention	9
shock protein	9
gene signature	9
induces nod	9
ecological study	9
individuals infected	9
global pandemic	9
respiratory disease	9
phase ii	9
pneumococcal vaccination	9
autoimmune inflammatory	9
programmed death	9
leprosy chemoprophylaxis	9
lower levels	9
type diabetes	9
old friends	9
gastrointestinal tract	9
viral rna	9
specific effect	9
draining lymph	9
urinary tract	9
muramyl dipeptide	9
production following	9
infected macrophages	9
vaccinated group	9
staphylococcus aureus	9
universal vaccination	9
aids vaccine	9
following vaccination	9
patients infected	9
proinflammatory cytokines	9
monoclonal antibodies	9
specific protection	9
epidemiological impact	9
death due	9
also reported	9
protease inhibitor	9
significant correlation	9
vaccine administration	9
innate cells	9
vaccine expressing	9
south korea	9
provided protection	9
odds ratio	9
subsequent influenza	9
months old	9
following influenza	9
hospital admission	9
neoadjuvant adt	9
high incidence	9
mammary gland	9
cell deficiency	9
bcg immunotherapy	9
viral clearance	9
bacillus subtilis	9
immunization program	9
mucocutaneous candidiasis	9
results suggest	9
results showed	9
trained macrophages	9
host cell	9
may result	9
membrane fusion	9
inflammatory mediators	9
prevent leprosy	9
delayed intervention	9
fever virus	9
penile cancer	9
immune deficiency	9
deficient mice	8
deficient patients	8
age years	8
risk groups	8
release syndrome	8
two different	8
nw adherent	8
vaccination strategies	8
several factors	8
guerin induces	8
among bcg	8
pediatric patients	8
immune phenotype	8
vaccine use	8
virulence genes	8
guerin vaccinations	8
may help	8
killer cell	8
old age	8
attenuated listeria	8
inflammatory diseases	8
bcg policies	8
guinea pig	8
coronavirus infections	8
immunocompromised patients	8
recombinant mycobacterium	8
leprosy post	8
subclass deficiency	8
rotavirus infection	8
among individuals	8
study suggests	8
experimental model	8
cellular responses	8
van der	8
different types	8
renal masses	8
polynomial growth	8
tests performed	8
genome sequence	8
united kingdom	8
lower covid	8
rank correlation	8
tlr agonists	8
tuberculosis knockout	8
immune suppression	8
mortality attributed	8
relatively low	8
cell defects	8
clinical symptoms	8
high mortality	8
primary infection	8
live vaccine	8
clinical study	8
exponential growth	8
may protect	8
posted august	8
systemic therapy	8
close contacts	8
induced mkp	8
large number	8
less likely	8
primary antibody	8
immunological examination	8
salmonella infection	8
bcg scar	8
retrospective analysis	8
congenital heart	8
specific mortality	8
new tb	8
mononuclear cells	8
pep administration	8
induces trained	8
signaling pathways	8
immunoglobulin replacement	8
middle high	8
phase trial	8
healthy subjects	8
european association	8
april th	8
cytokine response	8
weight children	8
well known	8
antigen synthesis	8
lamina propria	8
recent vaccination	8
boost vaccination	8
drug administration	8
potential impact	8
immunity induced	8
treat effects	8
findings suggest	8
pharmacological inhibition	8
stat phosphorylation	8
different time	8
immunization policies	8
death rates	8
leukocytoclastic vasculitis	8
cellular immune	8
year old	8
elderly population	8
mrna expression	8
strong association	8
care systems	8
histone modifications	8
may provide	8
trained cells	8
pattern recognition	8
muscle invasive	8
phop mutant	8
cell membrane	8
mucosal surfaces	8
small intestine	8
implementing sdr	8
infections caused	8
explanatory variables	8
vaccination score	8
significantly reduced	8
controlled pilot	8
recent reports	8
th immune	8
type iii	8
viral loads	8
balanced lethal	8
countries like	8
intradermal bcg	8
swedish population	8
modelling study	8
human volunteers	8
provide protection	8
phase i	8
increased cytokine	8
years ago	8
cellular immunity	8
phosphate dehydrogenase	8
sanger sequencing	8
bronchoalveolar lavage	8
disease control	8
iii secretion	8
chain reaction	8
transcriptional changes	8
vaccine protection	8
bcg treatment	8
time since	8
killer cells	8
specific vaccine	8
south african	8
post alignment	8
fungal infections	8
tissue disease	8
older age	8
intestinal epithelial	8
stage i	8
population structure	8
polymerase chain	8
springer nature	8
recovered patients	8
retrospective cohort	8
tuberculous meningitis	8
natural infection	8
cytokine release	8
systematic reviews	8
virus infections	8
key role	8
vaccination reduces	8
live vector	8
nervous system	8
web site	7
strain cvd	7
targeted therapies	7
trough levels	7
confirmed measles	7
entamoeba histolytica	7
latent tb	7
eligibility threshold	7
epidemiological data	7
population may	7
corona viruses	7
mortality among	7
positive control	7
supplementary table	7
specific antibodies	7
mucosal immunity	7
testing capacity	7
developed countries	7
may play	7
recent years	7
plasmid dna	7
york city	7
studies assessing	7
pylori infection	7
estimated using	7
risk populations	7
immunol doi	7
strain expressing	7
shown using	7
two weeks	7
antimicrobial activity	7
vaccine induces	7
leprosy research	7
prospective clinical	7
transcription factors	7
therapeutic options	7
cell death	7
wide range	7
naked dna	7
tb infections	7
disease patients	7
cells also	7
infected patients	7
low levels	7
also showed	7
transcription factor	7
ethnic groups	7
pnp deficiency	7
low cd	7
creative commons	7
several countries	7
chronic fatigue	7
calculate rho	7
type hypersensitivity	7
post auricular	7
mortality due	7
effective vaccine	7
clinical findings	7
fully understood	7
hyper igm	7
patients received	7
recombinant bacillus	7
universal policy	7
respiratory burst	7
acute infection	7
older people	7
severe coronavirus	7
leukocyte antigen	7
using three	7
five years	7
food allergy	7
without bcg	7
specific protective	7
epigenetic enzymes	7
indian sars	7
significant effect	7
resulting effect	7
molecular mimicry	7
critically ill	7
may reduce	7
federated states	7
immunological disorders	7
skin lesions	7
simian immunodeficiency	7
intravenous bcg	7
radical cystectomy	7
month old	7
glucan trained	7
institutional affiliations	7
current pandemic	7
time period	7
mucosal sites	7
letter country	7
immunomodulatory effects	7
early diagnosis	7
since bcg	7
disease caused	7
reconstitution inflammatory	7
cell mediated	7
current covid	7
days post	7
took place	7
including bcg	7
previously described	7
significant reduction	7
nature remains	7
molecular mechanisms	7
might also	7
autoimmune disorders	7
tb infection	7
see table	7
ii deficiency	7
skin infections	7
vitro assays	7
gulf war	7
antimycobacterial treatment	7
myeloid cells	7
liver function	7
increased il	7
effective treatment	7
staphylococcal mastitis	7
two cases	7
barr virus	7
regulated delayed	7
positive connections	7
remains neutral	7
recombinant attenuated	7
later stages	7
immodulon therapeutics	7
around april	7
systems biology	7
following bcg	7
viral entry	7
receptor binding	7
death rate	7
mammalian cells	7
countries according	7
demonstrated increased	7
one week	7
confer protection	7
target effects	7
vaccination scores	7
positive cases	7
west germany	7
among others	7
infant mortality	7
intravenous immunoglobulin	7
efficacy trials	7
childhood mortality	7
clinical research	7
vibrio cholerae	7
virus vaccine	7
influenza vaccines	7
two months	7
high confidence	7
superior protection	7
clinical use	7
mandatory immunization	7
therapeutics ltd	7
transplant bcgosis	7
using countries	7
surface expression	7
test results	7
vector vaccines	7
exclusion criteria	7
combined immunodeficiencies	7
posted march	7
eluted fractions	7
induced protection	7
higher prevalence	7
enhanced cytokine	7
first case	7
birth weight	7
immune mechanisms	7
gross domestic	7
country codes	7
infected mice	7
human leukocyte	7
yersinia pestis	7
injected animals	7
phagocytic cells	7
disorder characterized	7
active tuberculosis	7
neonatal bcg	7
pam cys	7
mucosal iga	7
vaccine strategies	7
higher bcg	7
miliary tuberculosis	7
antigen expression	7
major histocompatibility	7
jurisdictional claims	7
published maps	7
polio vaccine	7
mm edta	7
may offer	7
th cells	7
viral pathogens	7
mycobacterium obuense	7
two variables	6
mucosal delivery	6
flattened curves	6
target cells	6
population share	6
preventing covid	6
medical center	6
bcg delivery	6
herpes zoster	6
test positivity	6
national immunization	6
normal distribution	6
rcts will	6
ct scan	6
significant effects	6
vaccinated population	6
induced cross	6
obstructive pulmonary	6
therapeutic action	6
lethal system	6
possible role	6
lactoferrin protects	6
genes encoding	6
coronavirus covid	6
cd hla	6
isotype control	6
george syndrome	6
antibiotic therapy	6
aged years	6
different vaccines	6
cases reported	6
tb genome	6
broad range	6
less affected	6
severely affected	6
leprosy vaccine	6
granuloma formation	6
also induce	6
born residents	6
coverage rates	6
four patients	6
host defence	6
workers absenteeism	6
bullous pemphigoid	6
higher incidence	6
human peripheral	6
negative association	6
oral polio	6
cell entry	6
outpatient clinic	6
early phase	6
targeted therapy	6
immune activation	6
leprosy cases	6
measles vaccine	6
vector vaccine	6
pathogenic bacteria	6
healthy controls	6
chronic inflammation	6
national health	6
chronic obstructive	6
bcg programs	6
intravesical bacillus	6
rna polymerase	6
sample size	6
vaccines may	6
female patient	6
child survival	6
vaccine trials	6
high precision	6
atopic dermatitis	6
protein antigens	6
intradermal administration	6
additional data	6
pathogenic microbes	6
old female	6
cgd patients	6
energy production	6
central nervous	6
also suggested	6
early bcg	6
biomedical literature	6
immunity benefits	6
simplex virus	6
vaccinated countries	6
real time	6
without universal	6
world population	6
transmission dynamics	6
increasing age	6
vaccination predicts	6
taken together	6
blood mononuclear	6
primary immune	6
gaussian function	6
heterologous prime	6
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igm level	6
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mw vaccine	6
bovis bacille	6
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preliminary data	6
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two siblings	6
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control programs	6
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clinical condition	6
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urothelial cancer	6
oxygen species	6
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four months	6
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university medical	6
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primary human	6
among countries	6
track covid	6
within normal	6
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enterotoxigenic escherichia	6
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ige syndrome	6
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rd index	6
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igg mg	6
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cell line	6
saharan africa	6
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leprosy patient	6
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mycobacterial growth	6
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igm syndrome	6
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total cholesterol	6
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leprosy incidence	6
ill patients	6
respiratory viruses	6
pregnant women	6
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one patient	6
sign binding	6
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shigella flexneri	6
inflammatory processes	6
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tb vaccines	6
wasp gene	6
patients without	6
three age	6
immune dysregulation	6
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systemic immune	6
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neonatal sepsis	6
including sars	6
chronic lung	6
protein expression	6
scientificreports www	6
statistical precision	6
bp deletion	6
serious adverse	6
per population	6
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human primates	6
immunomodulatory properties	6
aldrich syndrome	6
acute lower	6
quarterly birth	6
reactive oxygen	6
overall mortality	6
tuberculosis vaccines	6
critical importance	6
western blot	6
immunity might	6
human primary	6
assess whether	6
small molecule	6
infections including	6
stat activation	6
linked glycosylation	6
blf treatment	6
currently underway	6
distancing measures	6
specific th	5
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trials will	5
cellular components	5
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cord blood	5
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east germany	5
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blood monocytes	5
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peritonitis virus	5
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eau guidelines	5
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leprosy contacts	5
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iu ml	5
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heterologous immunity	5
last months	5
rare autosomal	5
results demonstrated	5
versus bcg	5
data set	5
leishmania major	5
care system	5
policies due	5
tlr signaling	5
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paediatric tuberculosis	5
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mycobacterium vaccae	5
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tlr activation	5
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strains expressing	5
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human respiratory	5
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defining trained	5
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lactic acid	5
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guerin vaccination	5
expression level	5
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regular ivig	5
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study shows	5
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tuberculosis incidence	5
eukaryotic expression	5
glycolytic metabolism	5
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myeloid progenitor	5
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ige levels	5
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molecular genetic	5
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ace receptors	5
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adverse pathologic	5
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acute viral	5
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reducing susceptibility	5
viral challenge	5
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density lipoprotein	5
gaussian functions	5
vaccine production	5
bordetella pertussis	5
serum igg	5
diagnostic delay	5
medical care	5
antimicrobial properties	5
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human macrophages	5
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pid registry	5
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nature reviews	5
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vaccination affecting	5
systemic infections	5
clinical evaluation	5
peritoneal macrophages	5
protein sequence	5
bcg draining	5
targeting innate	5
next generation	5
case presentation	5
recombinant lactococcus	5
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related systemic	5
fatigue syndrome	5
agents may	5
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diagnostic criteria	5
grade disease	5
cytokines including	5
deletion within	5
cumulative number	5
switched memory	5
infectious peritonitis	5
based cohort	5
least squares	5
therapeutic vaccine	5
published data	5
blf displayed	5
infections may	5
differential covid	5
attenuated strains	5
human cells	5
modulatory effects	5
kinase phosphatase	5
global scale	5
genome sequencing	5
ic vaccine	5
dna methylation	5
possible explanation	5
johns hopkins	5
dependency ratio	5
free survival	5
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data used	5
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analyzed using	5
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rates per	5
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glycosylation sites	5
immune evasion	5
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delayed type	5
total covid	5
low cost	5
acid bacteria	5
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signal transduction	5
van den	5
infection may	5
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matched sibling	5
virus ankara	5
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highly enriched	5
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following exposure	5
higher temperatures	5
pulmonary tuberculosis	5
several reports	5
sequence polymorphisms	5
young group	5
alaska natives	5
vaccination causes	5
bcgosis patients	5
mutations found	5
protein interaction	5
significantly associated	5
proliferative response	5
related morbidity	5
designing mucosal	5
phase trials	5
cd expression	5
statistical methods	5
bowel disease	5
comparative genomics	5
nk cell	5
clostridium difficile	5
multiple linear	5
intravesical treatment	5
effector functions	5
circulating monocytes	5
health expenditure	5
central role	5
chronic bronchitis	5
rb deficiency	5
outcome variable	5
late diagnosis	5
may increase	5
reduce mortality	5
i interferon	5
young children	5
response following	5
possible association	5
three different	5
expressed genes	5
latent tuberculosis	5
chronic mucocutaneous	5
immunoprophylactic agents	5
health agency	5
vaccine policies	5
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antiphospholipid syndrome	5
linear model	5
age distribution	5
statistical computing	5
viral interference	5
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bcg training	5
pathologic outcomes	5
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neonatal mortality	5
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gene transcription	5
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study group	5
animal model	5
ordinary least	5
position paper	5
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evidence suggests	5
hopkins university	5
care units	5
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cell count	5
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statistical analyses	5
possible mechanism	5
pentose phosphate	5
adult volunteers	5
rapid development	5
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per country	5
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particular importance	5
bcg years	5
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surgical intervention	5
study also	5
tetanus toxin	5
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component system	5
risk reduction	5
pid cases	5
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scid mice	5
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systemic infection	5
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disease among	5
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dysfunctional immune	5
relative incidence	5
observational study	5
phase study	5
bcg injected	5
policy led	5
induce humoral	5
among adults	5
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virus replication	5
long lasting	5
substantial protection	5
increased expression	5
among contacts	5
sars patients	5
type responses	5
associated lymphoid	4
elderly people	4
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epigenetic mechanisms	4
years post	4
delayed resection	4
sequence analysis	4
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intercellular adhesion	4
infected people	4
kda lipoprotein	4
lung pathology	4
significant protection	4
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vaccinated children	4
severe infection	4
nontuberculous mycobacteria	4
studies showed	4
may reflect	4
experimental design	4
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medical faculty	4
coronavirus pneumonia	4
short duration	4
tiling array	4
rdrobust stata	4
persian gulf	4
authors thank	4
vaccine adjuvants	4
first group	4
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control cells	4
neoadjuvant chemotherapy	4
positive coefficient	4
genetic diversity	4
existing drugs	4
residual virulence	4
treated patients	4
emerging novel	4
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parasitic pathogens	4
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study predicting	4
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endothelial cell	4
adults aged	4
educates hematopoietic	4
global covid	4
disease prevention	4
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scientific brief	4
antibodies directed	4
older adults	4
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national program	4
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western blotting	4
component regulatory	4
born around	4
mycobacterial loads	4
incomplete kd	4
current study	4
high affinity	4
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edged sword	4
will need	4
genomic analysis	4
innate response	4
mice treated	4
mapk phosphorylation	4
brain tissue	4
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reverse transcriptase	4
much less	4
disease characterized	4
approximately one	4
polyarteritis nodosa	4
vectored vaccine	4
monocytes trained	4
immune complex	4
one hundred	4
cell arteritis	4
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kg dose	4
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coronavirus spike	4
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hsct bcg	4
response regulator	4
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irradiated bcg	4
like protease	4
response associated	4
crude covid	4
ethical issues	4
site erythema	4
cell clones	4
nationwide analysis	4
viral spread	4
new tuberculosis	4
smooth muscle	4
increased cd	4
structural proteins	4
dna vaccination	4
mtb antigens	4
pcr test	4
flow cytometric	4
immune effects	4
reviews microbiology	4
kda chaperonin	4
functional responses	4
following stimulation	4
mapks activation	4
mucosal antibodies	4
plasmodium falciparum	4
spread rapidly	4
significant bias	4
attenuated tuberculosis	4
oral vaccination	4
small renal	4
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coronavirus sars	4
vivo effects	4
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antiretroviral drugs	4
patients suffer	4
low birth	4
der heijden	4
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table contains	4
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mucosal vaccines	4
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genetic background	4
regulatory proteins	4
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correlation coefficient	4
platelet count	4
bcg disease	4
results indicate	4
generate protective	4
negative bacteria	4
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significant increase	4
kir ds	4
broad spectrum	4
underlying health	4
novel betacoronavirus	4
sirna transfected	4
adverse outcomes	4
transplant disease	4
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bcgosis group	4
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tuberculosis control	4
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universal bacillus	4
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autoimmune phenomena	4
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derived macrophages	4
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typhi vaccine	4
vs cells	4
patients undergoing	4
cells may	4
salmonella enteritidis	4
june th	4
individuals aged	4
five weeks	4
ii clinical	4
ng ml	4
oral cancer	4
confounding variables	4
secretion signal	4
key date	4
connecting bcg	4
recent data	4
case increase	4
specific survival	4
disease compared	4
four years	4
cytotoxic lymphocytes	4
past decade	4
low incidence	4
dpm outcome	4
negative control	4
induced mapk	4
antibody production	4
chemokine receptor	4
cells infected	4
american indians	4
atherosclerotic plaque	4
files human	4
underivatised sepharose	4
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detection rate	4
epithelioid cell	4
nucleic acid	4
oligomerization domain	4
listeria infection	4
first days	4
specific antigen	4
following mmr	4
opportunistic pathogen	4
patients reported	4
sars cov	4
stable expression	4
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cell immune	4
systemic immunization	4
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medical facilities	4
increased susceptibility	4
igg level	4
confident conclusion	4
following hbv	4
examination findings	4
pandemic across	4
infection rate	4
led us	4
neutrophil influx	4
currently available	4
among indians	4
immune thrombocytopenic	4
stk deficiency	4
healthy children	4
high temperature	4
median follow	4
vaccine steel	4
studies show	4
error term	4
four weeks	4
mycobacterial granulomas	4
one country	4
computed tomography	4
previously vaccinated	4
congenital infections	4
two populations	4
developed bcgosis	4
immunized mice	4
well accepted	4
vaccine will	4
salmonella infections	4
disseminated encephalomyelitis	4
hill criteria	4
leprosy case	4
th century	4
commons license	4
blf decreased	4
homozygous mutation	4
oxygen consumption	4
also considered	4
large cohort	4
glycolytic enzymes	4
lepromatous leprosy	4
new live	4
study reported	4
current policies	4
stat mutation	4
children clinical	4
deprivation therapy	4
many people	4
high grade	4
unvaccinated group	4
several different	4
mycobacterial diseases	4
potential utility	4
recurrent sinopulmonary	4
limited data	4
il rg	4
robust data	4
asymptomatic cases	4
appropriate treatment	4
also possible	4
reproduction numbers	4
increased protection	4
molecule bcg	4
receive bcg	4
recurrent bacterial	4
vaccination protect	4
following nonspecific	4
muscle cells	4
disease outcome	4
expressing ag	4
novel viruses	4
systematic literature	4
protective factor	4
earlier studies	4
two studies	4
lactoferrin lactoferrin	4
colonization factor	4
multiple doses	4
detailed analysis	4
testing rate	4
mg day	4
showed normal	4
respiratory system	4
years follow	4
type immunity	4
lps challenge	4
confounders like	4
study aimed	4
bank data	4
phop promoter	4
number nct	4
viral antigen	4
several hypotheses	4
significantly increased	4
breakage syndrome	4
complement deficiencies	4
lung function	4
untreated units	4
higher morbidity	4
susceptible individuals	4
new clinical	4
supporting evidence	4
disease virus	4
immunosuppressed mice	4
rheumatic diseases	4
skin biopsy	4
breast milk	4
cells expressing	4
unpublished report	4
vaccine initiative	4
per year	4
type infection	4
diagnostic ureteroscopy	4
patient presented	4
full term	4
pandemic restriction	4
stata command	4
vitro evolution	4
unrelated stimuli	4
three patients	4
viruses like	4
merit fc	4
indirect effect	4
also normal	4
safety data	4
potential confounders	4
parental bcg	4
targeted pathogens	4
inhibit sars	4
bcg complications	4
descriptive meta	4
binding oligomerization	4
respiratory illness	4
prevent covid	4
novel deletions	4
manufacturing capacity	4
significant influence	4
study population	4
viral protein	4
antiviral drugs	4
often present	4
autoimmune hepatitis	4
improve protection	4
macrophagic myofasciitis	4
mrna levels	4
pediatric department	4
drug interactions	4
foreign antigens	4
clinical response	4
vaccine mtbvac	4
hong kong	4
experimental animals	4
population age	4
acute disseminated	4
overall survival	4
rare disease	4
united nations	4
mycobacterial cell	4
bcg exposure	4
competing interests	4
received ivig	4
elevated serum	4
lymphocyte count	4
tuberculosis complex	4
lymphocyte subpopulations	4
immunization induces	4
experimental animal	4
soluble mycobacterial	4
great impact	4
supportive therapy	4
pathological findings	4
fatty acids	4
day post	4
local immune	4
commonly used	4
immunization may	4
cause mortality	4
mouse models	4
multiple studies	4
patients following	4
cmap positive	4
prospective study	4
rhode island	4
total deaths	4
since vaccination	4
two data	4
cd counts	4
protect mice	4
protects mice	4
network meta	4
negatively associated	4
viral antigens	4
leprosy protection	4
specific beneficial	4
cell infiltration	4
challenge model	4
study included	4
transgenic mice	4
mammalian target	4
data available	4
mucosal pathogens	4
immunological studies	4
equilibration buffer	4
induced signaling	4
human dendritic	4
cell deficiencies	4
preliminary results	4
glutamine metabolism	4
vaccination provides	4
strong positive	4
best fit	4
body mass	4
interferon gamma	4
hemolytic anemia	4
global partnership	4
convalescent phase	4
demystifying bcg	4
specific intercellular	4
protective innate	4
bcg reduced	4
intraperitoneal route	4
permutation tests	4
structural basis	4
supporting information	4
reducing covid	4
high morbidity	4
asymptomatic patients	4
universal vaccine	4
last five	4
infected mother	4
thrombocytopenic purpura	4
reproduction number	4
viral genome	4
global tuberculosis	4
pathogenic human	4
published studies	4
gdp per	4
intraperitoneal administration	4
lymphocyte populations	4
spectrum anti	4
individual countries	4
isolated human	4
heritable influences	4
normal range	4
well documented	4
groups representing	4
live recombinant	4
phor locus	4
adult pneumococcal	4
vaccines like	4
germ cell	4
pid center	4
mutation leading	4
human milk	4
immunosorbent assay	4
potential vaccine	4
future research	4
human use	4
last decade	4
antiviral immunity	4
small number	4
important factor	4
mucosal tibvs	4
candidate vaccine	4
study period	4
trial participants	4
clinical experience	4
responses elicited	4
study date	4
ulcerative colitis	4
patients compared	4
vector strain	4
mass spectrometry	4
prick test	4
toxoplasma gondii	4
disease outbreak	4
salmonella spp	4
tb disease	4
shigella spp	4
rapid onset	4
tuberculosis cases	4
active tb	4
orally administered	4
low covid	4
old male	4
vaccine repurposing	4
chronic gvhd	4
allowing us	4
known whether	4
another strength	4
modulatory effect	4
enhanced innate	4
herpes virus	4
data regarding	4
research center	4
mast cells	4
type vii	4
antigens may	4
defined syndromes	4
also reduced	4
four novel	4
integral component	4
infect dis	4
mice models	4
infusion rate	4
interaction database	4
iv method	4
vaccine based	4
requiring intensive	4
prospective cohort	4
following heterologous	4
remained significant	4
rd method	4
macrophage enriched	4
studied factor	4
case series	4
improved covid	4
vaccines provide	4
variant histology	4
mycobacterium avium	4
unvaccinated subjects	4
clinical phenotype	4
factors like	4
three cases	4
cell proliferation	4
endemic country	4
reported following	4
children born	4
low level	4
national bacille	4
testing strategy	4
reject fairly	4