bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
older adults	786
risk factors	394
immune system	316
health care	309
mean age	307
older people	298
age groups	295
age group	274
renal failure	256
blood pressure	246
immune response	241
physical activity	226
public health	222
mg kg	220
years old	205
abstract background	184
muscle mass	182
nephrotic syndrome	179
renal function	178
intensive care	176
increased risk	168
mg dl	164
significantly higher	164
risk factor	156
logistic regression	155
infectious diseases	154
skeletal muscle	150
mental health	146
control group	146
urinary tract	144
bone marrow	140
renal disease	140
united states	139
systematic review	137
oxidative stress	136
social distancing	136
cardiovascular disease	135
physical performance	132
old age	130
aged years	129
cohort study	128
ml min	125
acute respiratory	125
elderly patients	124
older persons	124
statistically significant	123
hong kong	117
heart failure	114
related diseases	113
elderly people	112
long term	111
breast cancer	111
innate immune	110
cognitive impairment	109
mitochondrial function	109
mitochondrial dysfunction	108
one patient	108
clinical trials	108
side effects	106
metabolic syndrome	105
gene expression	104
among older	103
body mass	101
two groups	100
kidney disease	99
renal biopsy	99
high risk	98
median age	98
kg day	98
peripheral blood	97
muscle strength	97
heart disease	97
respiratory tract	97
grip strength	97
coronavirus disease	96
significant differences	96
macular degeneration	96
mechanical ventilation	94
bronze age	94
significantly lower	93
mass index	93
immune responses	93
ng ml	91
one year	91
related macular	89
care unit	88
immune cells	87
stem cell	86
present study	86
doc id	85
gait speed	85
subjective age	85
cord uid	85
health services	85
older patients	84
birth weight	84
chronic renal	83
significant difference	82
primary care	82
physical function	82
life expectancy	81
family members	81
new york	80
tract infections	79
cd cd	79
results suggest	79
two patients	79
regression analysis	79
renal transplantation	78
respiratory syndrome	78
year old	78
serum creatinine	77
higher risk	77
older age	76
elderly persons	76
clinical features	75
chronic inflammation	75
body weight	75
pediatric patients	74
general population	74
tract infection	74
family history	74
daily living	74
significantly associated	74
mortality rate	74
stage renal	74
elderly population	73
respiratory failure	73
severe acute	72
mortality rates	72
fatality rate	72
sectional study	71
patients aged	71
important role	70
least one	70
protein intake	70
chronic diseases	70
educational attainment	69
pg ml	69
nk cells	69
may also	69
nitric oxide	69
hematopoietic stem	68
adverse events	68
health status	67
life satisfaction	67
inflammatory response	66
replacement therapy	66
cancer risk	66
cognitive function	66
respiratory distress	65
acute renal	65
novel coronavirus	65
adaptive immune	64
may lead	64
hiv aids	64
age range	63
old boy	63
nervous system	63
children aged	63
infectious disease	63
viral infections	63
inflammatory cytokines	63
young people	63
body composition	62
patients received	62
dwelling older	62
cytokine storm	62
health outcomes	61
term care	61
chronological age	61
clinical practice	60
flow cytometry	60
peritoneal dialysis	60
two years	59
nursing homes	59
primary immunodeficiency	59
cognitive decline	59
asthmatic patients	58
even though	58
findings suggest	58
weight loss	58
first year	57
functional decline	57
clinical trial	57
health promotion	56
lung disease	56
health problems	56
old girl	56
world health	56
stem cells	56
group i	55
reported cases	55
previous studies	55
diabetes mellitus	55
among patients	55
glomerular filtration	55
autosomal recessive	54
care services	54
lung cancer	54
age years	54
data collection	54
immune function	54
healthy children	53
case report	53
nutritional status	53
working group	53
high levels	53
age distribution	53
cardiovascular diseases	53
myocardial infarction	53
developing countries	53
factors associated	52
older women	52
average age	52
uric acid	52
linear regression	52
controlled trial	52
confidence interval	52
three patients	51
end stage	51
family care	51
prospective study	51
cellular senescence	51
randomized controlled	51
renal insufficiency	51
healthy aging	50
social support	50
clinical course	50
liver transplantation	50
university hospital	50
young adults	50
epithelial cells	49
type diabetes	49
chronic kidney	49
assessed using	49
adipose tissue	49
significantly increased	49
filtration rate	49
transplant recipients	49
cardiovascular risk	49
renal transplant	49
growth factor	49
type i	49
significantly different	49
care system	48
patients without	48
adverse effects	48
kidney transplantation	48
european countries	48
one case	48
previously reported	47
health organization	47
home care	47
determine whether	47
healthy controls	47
prospective cohort	47
converting enzyme	47
year period	46
influenza vaccination	46
physical health	46
socioeconomic status	46
control study	46
physical exercise	46
exome sequencing	46
case fatality	46
drug use	46
younger adults	46
aging process	46
blood samples	46
pediatric nephrology	46
age classes	45
acute rejection	45
cssa recipients	45
per year	45
neovascular age	45
emergency department	45
frail older	45
dendritic cells	44
proinflammatory cytokines	44
generational differences	44
later life	44
clinical presentation	44
people aged	44
cardiac surgery	44
cell function	44
combined immunodeficiency	44
cd cells	43
age class	43
nursing home	43
respiratory infections	43
group ii	43
old male	43
made available	43
pulmonary disease	43
physical frailty	43
cell types	42
total number	42
international license	42
white matter	42
disease control	42
lung function	42
author funder	42
stool samples	42
genetic testing	42
patients showed	42
senescent cells	42
standard deviation	42
copyright holder	42
social constructionist	42
granted medrxiv	42
physical examination	41
different age	41
healthy ageing	41
normal range	41
odds ratio	41
frailty status	41
retrospective study	41
regression model	41
zinc supplementation	41
urinary protein	41
gestational age	41
endothelial cells	40
may help	40
health system	40
complete remission	40
central nervous	40
fatality rates	40
adult patients	40
viral infection	39
performed using	39
data suggest	39
pilot study	39
syndrome coronavirus	39
increasing age	39
autosomal dominant	39
recent years	39
among women	38
immune deficiency	38
intervention group	38
natural history	38
also found	38
much higher	38
health insurance	38
significant increase	38
coronary heart	38
recurrent infections	38
social isolation	38
low muscle	38
cell death	38
related changes	38
nk cell	38
distress syndrome	38
depressive symptoms	38
measured using	37
biological aging	37
results show	37
high prevalence	37
national health	37
immune dysregulation	37
frailty index	37
renal tubular	37
analysis showed	37
clinical characteristics	37
regression models	37
lifespan perspective	37
poster sessions	37
cell transplantation	37
critically ill	37
advanced age	37
controlled trials	37
spinal cord	37
bubonic plague	37
compound heterozygous	37
clinical data	37
handgrip strength	36
air pollution	36
chain cleavage	36
younger age	36
study population	36
older workers	36
polymerase chain	36
sample size	36
constructionist perspective	36
current study	36
per day	36
cohort effects	36
functional capacity	36
iga nephropathy	36
older men	36
machine learning	36
animal models	36
chain reaction	36
statistical analysis	35
several studies	35
fatty acids	35
significant correlation	35
multivariate analysis	35
may play	35
mycophenolate mofetil	35
walking speed	35
magnetic resonance	35
chronic obstructive	35
early diagnosis	35
may contribute	35
york city	35
blood flow	35
demographic data	35
hip fracture	35
hiv infection	35
urban areas	35
cognitive frailty	35
year follow	35
low levels	35
adults aged	35
inclusion criteria	35
united kingdom	35
contact matrices	35
obstructive pulmonary	35
two weeks	35
abdominal pain	35
six months	35
results indicate	35
last decade	34
developmental delay	34
confidence intervals	34
mean duration	34
left ventricular	34
environmental factors	34
total population	34
high level	34
contact patterns	34
women aged	34
preliminary results	34
diagnostic criteria	34
segmental glomerulosclerosis	34
patients admitted	34
wide range	34
lupus nephritis	34
longitudinal study	34
term follow	34
protective effect	34
biological age	33
liver disease	33
folic acid	33
cervical cancer	33
graft survival	33
significant association	33
two cases	33
mri brain	33
recent studies	33
innate immunity	33
palliative care	33
near east	33
clinical manifestations	33
months later	33
pulmonary hypertension	33
muscle function	33
predictive value	33
severe covid	33
community health	33
first time	33
smooth muscle	33
creatinine clearance	33
cytokine production	33
muscle weakness	33
social security	32
graft function	32
alcohol consumption	32
chronic disease	32
serum levels	32
heart rate	32
higher levels	32
systemic inflammation	32
health needs	32
statistical significance	32
associated genes	32
contact matrix	32
mononuclear cells	32
dmsa scan	32
old female	32
three months	32
cell responses	32
within hours	32
alport syndrome	32
psychological distress	32
version posted	32
amino acids	32
cell receptor	32
life span	32
four patients	32
steroid therapy	32
functional status	32
class i	31
may provide	31
study design	31
human lung	31
lung transplantation	31
early detection	31
th percentile	31
control groups	31
nlrp inflammasome	31
drug users	31
multiple sclerosis	31
south africa	31
cell proliferation	31
informed consent	31
coronary artery	31
focal segmental	31
heart age	31
care facilities	31
metabolic acidosis	31
upper respiratory	31
data collected	31
relative risk	31
adaptive immunity	31
confirmed cases	30
immune cell	30
well known	30
one week	30
human bocavirus	30
cell senescence	30
biopsy showed	30
widely used	30
second wave	30
independently associated	30
virus infection	30
telomere length	30
spatial indicators	30
life course	30
serum albumin	30
survival rates	30
infection fatality	30
cause mortality	30
health centre	30
patients treated	30
insulin resistance	30
renal diseases	30
artery disease	30
transplant patients	30
significant improvement	30
better understand	30
immunoglobulin replacement	30
commonly used	30
np swabs	30
polio morbidity	30
clinical studies	30
odds ratios	30
birth cohort	30
disease severity	30
future research	29
per week	29
weight gain	29
disease progression	29
acute phase	29
case series	29
common cause	29
age related	29
adverse outcomes	29
literature review	29
whole exome	29
substance use	29
cell cycle	29
study period	29
signaling pathway	29
reactive protein	29
study showed	29
higher rates	29
renal scarring	29
health service	29
one month	29
urban health	29
mg day	29
cholesterol side	29
inner city	28
signaling pathways	28
mortality risk	28
medical history	28
also associated	28
gut microbiota	28
urine samples	28
mg protein	28
reactive oxygen	28
six patients	28
cell lymphopenia	28
pediatric intensive	28
retrospective analysis	28
older population	28
study group	28
mainland china	28
mixing patterns	28
epidemiological studies	28
among elderly	28
stress resilience	28
eight patients	28
transmission dynamics	28
results showed	28
less likely	28
five patients	28
patients receiving	28
descriptive statistics	28
cvid patients	28
patients developed	28
cell counts	28
beneficial effects	28
respiratory symptoms	28
cells ul	28
response rate	28
social services	27
vascular disease	27
old mice	27
will also	27
study aimed	27
cssa system	27
medical care	27
motor neuron	27
protein excretion	27
school closures	27
primary health	27
severe combined	27
creatinine ratio	27
analyzed using	27
healthcare system	27
electron microscopy	27
among others	27
autoimmune diseases	27
living alone	27
next generation	27
elderly individuals	27
lung injury	27
viral load	27
thymic involution	27
computed tomography	27
low dose	27
younger people	27
average number	27
transcription factor	27
mortality among	26
young children	26
body fat	26
national institute	26
advancing age	26
health effects	26
performance battery	26
cell repertoire	26
min mg	26
multiple regression	26
common variable	26
elderly care	26
older individuals	26
type ii	26
kidney transplant	26
deaths per	26
calorie restriction	26
people living	26
medical records	26
dna methylation	26
last years	26
per patient	26
human aging	26
acute gastroenteritis	26
care providers	26
care needs	26
mean follow	26
regression analyses	26
vesicoureteral reflux	26
clinical symptoms	26
aging research	26
randomly selected	26
organ failure	26
cvd risk	26
mental state	26
amino acid	26
street youth	26
three times	26
infection rates	26
differential diagnosis	26
hospitalized patients	26
rural areas	26
bacterial infections	26
interstitial fibrosis	26
significantly reduced	25
data analysis	25
chronic lung	25
one study	25
expectations regarding	25
clinical diagnosis	25
health professionals	25
social frailty	25
higher prevalence	25
chronic pain	25
will provide	25
among community	25
investigate whether	25
birth year	25
regarding aging	25
colorectal cancer	25
determined using	25
control subjects	25
fi rst	25
younger patients	25
health policy	25
future studies	25
risk groups	25
pregnant women	25
world studies	25
social capital	25
blood levels	25
retrospective cohort	25
mrna expression	25
among children	25
renal dysfunction	25
outcome measures	25
low physical	25
renal involvement	25
chronic inflammatory	25
clinical research	25
cancer patients	25
patients died	25
chart review	25
blood mononuclear	24
oxygen species	24
public transport	24
negative affect	24
general hospital	24
peer review	24
significantly decreased	24
ml kg	24
protein expression	24
waiting list	24
transmission rate	24
resonance imaging	24
infected individuals	24
muscle biopsy	24
fatty acid	24
natural killer	24
blood cells	24
social justice	24
mouse model	24
clinical outcomes	24
south korea	24
many countries	24
short physical	24
disease burden	24
cell subsets	24
per person	24
study aims	24
dietary intake	24
antibody deficiency	24
health survey	24
grade inflammation	24
mitochondrial dna	24
patients may	24
health education	24
patients underwent	24
five years	24
income countries	24
function tests	24
paediatric patients	24
key role	24
reproduction number	24
kidney function	24
random sample	24
first case	24
high mortality	23
slit diaphragm	23
three different	23
renal replacement	23
symptomatic infectious	23
health information	23
influenza vaccine	23
using data	23
median follow	23
paediatric neurology	23
higher mortality	23
muscle cells	23
included studies	23
baseline characteristics	23
risk group	23
prognostic factors	23
private sector	23
inflammatory mediators	23
study sample	23
time period	23
social care	23
high blood	23
months old	23
caloric restriction	23
patients presented	23
selenium deficiency	23
significant reduction	23
focus groups	23
pd patients	23
fat mass	23
patient survival	23
well tolerated	23
soft tissue	23
matched controls	23
dent disease	23
medical center	23
missing data	23
variable immunodeficiency	23
million people	23
high school	23
patient group	23
metabolic alkalosis	23
liver transplant	23
cox proportional	23
older adult	23
may explain	23
mathematical model	23
hospital admissions	23
epidemic threshold	23
patients presenting	23
herpes zoster	23
health issues	23
death rate	23
graft failure	23
hazard ratio	23
two different	23
mitochondrial activity	22
within days	22
much lower	22
african american	22
vaccination coverage	22
service delivery	22
month period	22
total protein	22
first hours	22
mean time	22
mitochondrial biogenesis	22
correlation coefficient	22
demographic characteristics	22
large number	22
term outcome	22
health research	22
seven patients	22
early stages	22
early childhood	22
consecutive patients	22
inflammatory state	22
rating scale	22
cell activation	22
social participation	22
low income	22
disease activity	22
presentation will	22
previously described	22
dna damage	22
urine culture	22
growth retardation	22
may reflect	22
mechanically ventilated	22
child health	22
integrated care	22
clinical phenotype	22
cardiovascular events	22
leading cause	22
examination revealed	22
posted may	22
positive correlation	22
differ significantly	22
last year	22
independent risk	22
genes involved	22
molecular mechanisms	22
marital status	22
epidemiological data	22
subjective well	22
necrosis factor	22
cell exhaustion	22
overall mortality	22
nine patients	22
lower limb	22
western blot	22
without controls	22
calculated using	22
observational study	22
respiratory disease	22
three groups	22
data indicate	22
first months	22
ischemic stroke	21
mg ml	21
patients years	21
first episode	21
important risk	21
dental caries	21
showed normal	21
normal renal	21
underlying disease	21
patient developed	21
mechanisms underlying	21
dna repair	21
care units	21
hiv positive	21
alcohol use	21
pension system	21
may result	21
cases per	21
high incidence	21
postmenopausal women	21
infectious complications	21
significant decrease	21
creative commons	21
evidence suggests	21
incidence rates	21
cell differentiation	21
among adults	21
diabetic patients	21
cumulative number	21
four years	21
blood glucose	21
skin cancer	21
physical fitness	21
successful aging	21
control measures	21
decision making	21
yellow fever	21
south asian	21
signal transduction	21
polio epidemic	21
severe disease	21
years later	21
older person	21
mobility disability	21
sea peoples	21
included patients	21
minimal change	21
significantly correlated	21
perceived stress	21
asymptomatic infectious	21
low birth	21
social media	21
inflammatory markers	21
study shows	21
multivariate logistic	21
health literacy	21
streptococcus pneumoniae	21
related disease	20
reproductive number	20
positive patients	20
premature infants	20
old individuals	20
will need	20
small number	20
social networks	20
ormond street	20
data sets	20
negative impact	20
newborn screening	20
year age	20
increased susceptibility	20
months post	20
vaccination strategies	20
year survival	20
intravenous immunoglobulin	20
many studies	20
closely related	20
cell development	20
chronic stress	20
inflammasome activation	20
uremic syndrome	20
native dutch	20
patients older	20
ray absorptiometry	20
healthy subjects	20
acute pyelonephritis	20
system capacity	20
neurological examination	20
healthy older	20
chronic low	20
heterozygous mutations	20
respiratory diseases	20
service providers	20
cohort studies	20
urban poor	20
old people	20
great ormond	20
greater risk	20
persons aged	20
important factor	20
saharan africa	20
lifestyle factors	20
normal controls	20
systolic blood	20
lung diseases	20
research center	20
cancer registry	20
may affect	20
dialysis patients	20
visual outcomes	20
major risk	20
healthcare professionals	20
per min	20
analysis revealed	20
arterial blood	20
usual care	20
immune functions	20
hearing loss	20
range proteinuria	20
significant risk	20
elderly subjects	20
health problem	20
critical role	20
poor outcome	20
early life	19
carotid artery	19
cell carcinoma	19
frailty among	19
inflammatory cytokine	19
estimated using	19
lower respiratory	19
total cholesterol	19
work ability	19
labor market	19
positive cells	19
steroid resistant	19
angiotensin converting	19
living standards	19
higher incidence	19
smoking cessation	19
age category	19
one child	19
primary outcome	19
american neurological	19
significantly improved	19
study conducted	19
retrospective review	19
protein levels	19
nuclear factor	19
authors declare	19
term survival	19
viral replication	19
randomized clinical	19
ill children	19
better understanding	19
many cases	19
patient presented	19
infectious individuals	19
neurodegenerative diseases	19
severe cases	19
general practice	19
remained stable	19
case presentation	19
organ transplantation	19
lifespan development	19
diastolic blood	19
sexually transmitted	19
time point	19
aged individuals	19
antibody response	19
past years	19
sensitivity analysis	19
neurological association	19
beneficial effect	19
one hundred	19
comprehensive geriatric	19
health conditions	19
monoclonal antibodies	19
chronic allograft	19
resistance training	19
randomised controlled	19
healthy elderly	19
elderly asthmatic	19
many patients	19
cerebrospinal fluid	19
ckd stage	19
congenital heart	19
genetic analysis	19
european working	19
microscopic hematuria	19
trough levels	19
will help	19
univariate analysis	19
population health	19
serial interval	19
risk assessment	19
seizure frequency	19
research team	19
protein synthesis	19
infected patients	19
renal damage	19
retirement age	18
may represent	18
vascular risk	18
primary immune	18
cell transplant	18
oral health	18
damaged mitochondria	18
angiotensin ii	18
assisted living	18
higher among	18
nephrotic range	18
studies suggest	18
ad patients	18
immunosuppressive therapy	18
influenza virus	18
cumulative incidence	18
mental status	18
fold increase	18
tissue damage	18
age structure	18
future directions	18
central role	18
social class	18
medrxiv preprint	18
focus group	18
cross sectional	18
gene mutation	18
gene encoding	18
arterial hypertension	18
ethnic minority	18
gold standard	18
differentially expressed	18
health behaviors	18
patients whose	18
energy intake	18
study demonstrates	18
poor health	18
frailty screening	18
renal impairment	18
high dose	18
prospective studies	18
secretory phenotype	18
disease onset	18
san francisco	18
amyotrophic lateral	18
health systems	18
adult population	18
lipid profile	18
enzyme activity	18
paediatric intensive	18
kidney biopsy	18
young copd	18
hospital stay	18
late bronze	18
significant change	18
cell lines	18
urine protein	18
harm reduction	18
plasma exchange	18
longitudinal studies	18
sarcopenic obesity	18
significantly greater	18
lymph node	18
likely due	18
three years	18
ageing society	18
sex differences	18
incidence rate	18
survival rate	18
different countries	18
emergency departments	18
ct scan	18
within months	18
aged mice	18
street hospital	18
humoral immunity	18
educational level	18
wild type	18
recent study	18
geriatric assessment	18
nutritional support	18
demographic information	18
old rats	18
individuals aged	18
reserve capacity	18
airway inflammation	18
cell line	18
angiotensin system	18
showed significant	18
hospital admission	18
may influence	18
cell count	18
myeloid cell	18
opportunistic infections	18
increased expression	18
clinical information	18
lateral sclerosis	18
influenza pandemic	18
substance abuse	18
previous research	18
may reduce	18
newly diagnosed	18
polyunsaturated fatty	17
alkaline phosphatase	17
dysfunctional mitochondria	17
screening tool	17
specific antibody	17
affected individuals	17
related mortality	17
aging processes	17
similar results	17
middle east	17
general health	17
influenza vaccines	17
social contact	17
nerve conduction	17
developed countries	17
main cause	17
across different	17
adverse health	17
heat shock	17
nephritic syndrome	17
successfully treated	17
related decline	17
patient characteristics	17
may occur	17
ischemic heart	17
overall survival	17
basement membrane	17
may increase	17
protein kinase	17
mouse models	17
study will	17
zinc ion	17
mitochondrial health	17
status epilepticus	17
th day	17
group compared	17
increased significantly	17
research project	17
grade iii	17
ethnic groups	17
statistical analyses	17
gender differences	17
potential role	17
disease transmission	17
patients referred	17
cancer screening	17
organ damage	17
hemolytic uremic	17
individual level	17
immune activation	17
generation sequencing	17
mediterranean diet	17
hittite empire	17
particularly important	17
cells may	17
endoplasmic reticulum	17
data sources	17
creatinine level	17
related differences	17
frail elderly	17
lymph nodes	17
poisson regression	17
muscle quality	17
frailty phenotype	17
also known	17
increased levels	17
pediatric renal	17
major role	17
lupus erythematosus	17
ejection fraction	17
mitochondrial turnover	17
among people	17
communicable diseases	17
population ageing	17
outpatient clinic	17
clinical examination	17
first years	17
higher rate	17
case study	17
different ages	17
informal care	17
two main	17
renal survival	17
case reports	17
prostate cancer	17
one hand	17
aerobic glycolysis	17
drinking water	17
two decades	17
lowe syndrome	17
inversely associated	17
per month	17
economic status	17
weeks gestation	17
partial remission	17
among men	17
disease prevention	17
lymphoid cells	17
will likely	17
treatment group	17
liver function	17
frail women	17
period effects	16
viral hepatitis	16
liver biopsy	16
like receptor	16
vaccine development	16
positively associated	16
nicotinamide riboside	16
health benefits	16
kidney diseases	16
survival analysis	16
salt wasting	16
syncytial virus	16
steroid sensitive	16
cx cl	16
patients undergoing	16
sexual health	16
csa treatment	16
food insecurity	16
epidemiologic studies	16
right place	16
cmv infection	16
combined therapy	16
liver failure	16
sedentary behavior	16
one third	16
preterm infants	16
high doses	16
living conditions	16
chair stand	16
baseline va	16
medical science	16
homozygous mutation	16
neurological symptoms	16
negative correlation	16
patients infected	16
related quality	16
rheumatoid arthritis	16
mitochondrial dynamics	16
cell aging	16
study provides	16
renal artery	16
congestive heart	16
septic shock	16
lipid peroxidation	16
nutritional assessment	16
tubular function	16
mean arterial	16
bone density	16
cerebrovascular disease	16
trace elements	16
biopsy specimens	16
groups according	16
lower extremity	16
unintentional weight	16
proximal tubular	16
infection control	16
neonatal period	16
symptom onset	16
also showed	16
epidemiological characteristics	16
older populations	16
increased mortality	16
years ago	16
arterial stiffness	16
reported symptomatic	16
many older	16
patient data	16
visual acuity	16
myeloid cells	16
target population	16
last months	16
markov chain	16
vascular smooth	16
cell type	16
high frequency	16
study included	16
oral prednisone	16
year mortality	16
mean scores	16
proportional hazards	16
copd patients	16
modelling study	16
poor prognosis	16
allograft nephropathy	16
growth hormone	16
zoster virus	16
studies showed	16
arterial pressure	16
financial situation	16
elevated levels	16
old woman	16
mycobacterium tuberculosis	16
global health	16
increased incidence	16
central venous	16
cell numbers	16
mental retardation	16
muscle wasting	16
idiopathic nephrotic	16
lean mass	16
tubular atrophy	16
key factor	16
observational studies	16
respiratory function	16
mean number	16
different types	16
public sector	16
age matched	16
potential confounders	16
will allow	16
patients will	16
extracellular matrix	16
aging population	16
cell surface	16
middle age	16
tumor necrosis	16
women living	16
cardiac output	16
cerebral palsy	16
strongly associated	16
mutant mice	16
will discuss	16
serum concentrations	16
epidemiological research	16
social factors	16
important cause	16
exclusion criteria	16
preventive measures	16
geriatric syndromes	16
airway obstruction	16
first step	16
ige levels	16
brain injury	16
time points	16
submission id	16
days later	16
last follow	16
mononuclear cell	15
many people	15
inflammatory process	15
psychological stress	15
missense mutation	15
lower risk	15
transcript levels	15
respiratory system	15
showed higher	15
related chronic	15
analysed using	15
decision tree	15
cd cell	15
square test	15
united nations	15
zinc deficiency	15
cancer mortality	15
near future	15
also increased	15
viral respiratory	15
patient groups	15
flow cytometric	15
past decade	15
girl presented	15
second phase	15
bacterial infection	15
step life	15
analysis using	15
allow us	15
renal functions	15
three children	15
muscle quantity	15
public open	15
supplementary section	15
inflammatory disease	15
scoping review	15
roc curve	15
risk patients	15
patient population	15
venous blood	15
blood cell	15
labour force	15
transmission rates	15
urban settings	15
immune senescence	15
average time	15
renal scars	15
health interventions	15
skin lesions	15
role played	15
abdominal obesity	15
inborn errors	15
resistant nephrotic	15
especially important	15
main risk	15
duffy null	15
community services	15
longitudinal data	15
sample sizes	15
elderly men	15
systemic lupus	15
heart transplantation	15
light microscopy	15
early stage	15
pulmonary fibrosis	15
glomerular disease	15
study suggests	15
per se	15
prevalence rates	15
respiratory syncytial	15
several years	15
social determinants	15
significant effect	15
labor force	15
calcineurin inhibitor	15
dengue virus	15
based research	15
population based	15
critical care	15
one another	15
previous reports	15
aerobic exercise	15
across countries	15
mental illness	15
treated patients	15
study examined	15
medical treatment	15
often associated	15
muscle thickness	15
several factors	15
lung infection	15
geriatric medicine	15
chronic conditions	15
renal tissue	15
hemolytic anemia	15
vascular resistance	15
sppb score	15
healthcare services	15
human rights	15
general practitioners	15
blood gases	15
interstitial nephritis	15
data will	15
urinary excretion	15
positive cases	15
taken together	15
antibody production	15
low grade	15
heterozygous mutation	15
renal allograft	15
median duration	15
clinical evidence	15
low serum	15
frail individuals	15
pao fio	15
motor function	15
mental disorders	15
also significantly	15
ex vivo	15
child development	15
prism score	15
pathogenic variants	15
oxidative damage	15
gastrointestinal tract	15
fold increased	15
preliminary data	15
generational groups	15
screening programme	15
per capita	15
broad spectrum	15
granulomatous disease	15
energy expenditure	15
remains unclear	15
mri showed	15
exercise program	15
among young	15
epigenetic changes	15
first days	15
exact test	15
elderly patient	15
clinical picture	15
patient age	15
instrumental activities	15
great deal	15
group patients	15
showed significantly	15
adults may	15
national center	15
older asthmatic	15
los angeles	15
weeks later	15
supplementary table	15
community members	15
disease risk	15
antibiotic therapy	15
across multiple	15
like growth	15
platelet count	15
high quality	15
vaccine efficacy	15
deficient patients	15
also used	15
geriatric syndrome	15
correlation coefficients	15
take care	14
risk communication	14
cell response	14
relatively low	14
chronic respiratory	14
smoking status	14
infant mortality	14
vertical confinement	14
local community	14
growth failure	14
urinary nag	14
aging study	14
social relationships	14
patients compared	14
autoimmune disease	14
matter lesions	14
report two	14
life insurance	14
post transplant	14
african americans	14
frailty syndrome	14
metabolic disorders	14
pivotal role	14
domestic dogs	14
local health	14
lower levels	14
case numbers	14
successful ageing	14
old man	14
ageing population	14
older ages	14
patients diagnosed	14
cultured cells	14
irish journal	14
studies indicate	14
health study	14
asthma control	14
intracellular zinc	14
data available	14
urinary incontinence	14
lymphocyte subsets	14
group included	14
primary vur	14
evoked potentials	14
st century	14
innate lymphoid	14
will increase	14
paper will	14
treatment regimens	14
induction therapy	14
healthy individuals	14
young age	14
evaluated using	14
mosm kg	14
will continue	14
assess whether	14
risk profile	14
selection bias	14
allostatic load	14
icu admission	14
recent advances	14
within normal	14
functional disability	14
skin biopsy	14
remained unchanged	14
state examination	14
among age	14
economic conditions	14
barthel index	14
every weeks	14
homeless people	14
research questions	14
cancer cases	14
intervention program	14
vur grade	14
healthy control	14
healthcare providers	14
colon cancer	14
pediatric population	14
tubular cells	14
mg daily	14
examination showed	14
genetic factors	14
old patients	14
i interferon	14
massage therapy	14
children received	14
adverse reactions	14
cell lymphoma	14
degenerative joint	14
literature search	14
back pain	14
symptomatic infections	14
family member	14
nphs mutations	14
otitis media	14
disease course	14
first week	14
across age	14
observed among	14
showed increased	14
muscle protein	14
immune changes	14
may cause	14
negative self	14
grade i	14
creatinine levels	14
zinc release	14
copy number	14
another important	14
participants completed	14
progressive renal	14
severe renal	14
short term	14
first report	14
ketogenic diet	14
see table	14
related disorders	14
antibody titers	14
human coronaviruses	14
cd ra	14
waist circumference	14
frail patients	14
cells mcl	14
medical conditions	14
security system	14
lower urinary	14
service provision	14
social contacts	14
policy makers	14
calcium excretion	14
eastern europe	14
significant negative	14
crucial role	14
previously healthy	14
complex i	14
laboratory data	14
sars coronavirus	14
lower limbs	14
psychosocial factors	14
intracranial hypertension	14
serious infections	14
grade vur	14
still unclear	14
nphs gene	14
body size	14
higher scores	14
uk objective	14
insulin sensitivity	14
inflammatory effects	14
neurological disorders	14
head injury	14
therapeutic strategies	14
associated diseases	14
death rates	14
metabolic diseases	14
infectious agents	13
memory cd	13
therapeutic intervention	13
evidence indicates	13
least two	13
first reported	13
defined using	13
pulmonary vascular	13
normal aging	13
structured model	13
social life	13
complement activation	13
whole blood	13
diffuse mesangial	13
aging labour	13
lived environments	13
major cause	13
specific age	13
vascular diseases	13
health indicators	13
effective treatment	13
movement disorders	13
movement disorder	13
test results	13
significantly related	13
dock deficiency	13
passive smoking	13
participants also	13
related health	13
uk real	13
general practitioner	13
time spent	13
ethnic minorities	13
dm patients	13
time pcr	13
primary disease	13
school year	13
muscle fibers	13
groups based	13
parenteral nutrition	13
will lead	13
promote healthy	13
tubular dysfunction	13
phase i	13
may improve	13
evaluate whether	13
public policy	13
first wave	13
flow rate	13
animal studies	13
steroid treatment	13
neurological diseases	13
fixed effects	13
inflammatory status	13
increased production	13
atrial fibrillation	13
teaching hospital	13
data show	13
white blood	13
renal ultrasound	13
healthy adults	13
intermittent fasting	13
available data	13
class ii	13
mammalian target	13
highly significant	13
expression patterns	13
single cell	13
seizure onset	13
hand grip	13
cox regression	13
every year	13
well established	13
statistical methods	13
vascular endothelial	13
mean difference	13
increased prevalence	13
collected data	13
fanconi syndrome	13
sleep quality	13
mm hg	13
early onset	13
relapse rate	13
attack rate	13
mhc class	13
older recipients	13
dependent manner	13
clinical management	13
high rate	13
stand test	13
real time	13
ms patients	13
clinical study	13
airway pressure	13
time series	13
rudolph zacher	13
financial crisis	13
child poverty	13
cord blood	13
crp levels	13
male sex	13
cancer incidence	13
study found	13
infected cases	13
inflammatory diseases	13
significant impact	13
asian msm	13
high glucose	13
open access	13
antigen presentation	13
multivariate analyses	13
individual differences	13
children admitted	13
vast majority	13
reticulum stress	13
developed severe	13
human development	13
mean score	13
kg min	13
laboratory findings	13
health related	13
failure due	13
serum calcium	13
urban communities	13
increasing number	13
infected children	13
aging immune	13
host response	13
give rise	13
copd group	13
stress responses	13
cultural groups	13
significant correlations	13
normal levels	13
exercise training	13
cells mm	13
medication use	13
infected people	13
surveillance system	13
positively correlated	13
drug abuse	13
serum uric	13
medical services	13
chronic granulomatous	13
intrauterine growth	13
serious adverse	13
acute myocardial	13
graft loss	13
children presenting	13
functional studies	13
laboratory tests	13
pulmonary artery	13
adjusted cfrs	13
pulmonary tuberculosis	13
global burden	13
retrospectively reviewed	13
motor neurons	13
elderly women	13
binding protein	13
rare disease	13
qualitative study	13
new onset	13
clinically relevant	13
severe asthma	13
adverse effect	13
macroscopic hematuria	13
pulse therapy	13
normal values	13
group differences	13
diabetic nephropathy	13
uncertain significance	13
past year	13
asthma exacerbations	13
inflammatory responses	13
care systems	13
relative survival	13
monoclonal antibody	13
endotracheal intubation	13
evolutionary perspective	13
adults undergoing	13
disease caused	13
vaccine response	13
urinary ph	13
lung inflammation	13
egfr sch	13
potential therapeutic	13
sensory loss	13
injection drug	13
iron age	13
inflammatory processes	13
east respiratory	13
multiple organ	13
recurrent uti	13
two age	13
examine whether	13
rates among	13
personal resources	13
first line	13
lower incidence	13
initial presentation	13
joint disease	13
cigarette smoking	13
icu syndrome	13
drug treatment	13
lean body	13
trough level	13
clinical evaluation	13
life events	13
appendicular skeletal	13
immunosuppressive treatment	13
retrospective chart	13
pathogenic variant	13
immune complex	13
pediatric icu	12
respiratory infection	12
infections among	12
control policies	12
gene polymorphism	12
transmitted diseases	12
virus infections	12
negative effects	12
human immune	12
following criteria	12
much less	12
factors influencing	12
aged rats	12
intravitreal ranibizumab	12
cigarette smoke	12
specific health	12
food intake	12
text messages	12
working age	12
surgical procedures	12
surveillance systems	12
consanguineous parents	12
compared using	12
measles transmissions	12
tcr repertoire	12
major causes	12
acute coronary	12
standard errors	12
primary immunodeficiencies	12
smokers vs	12
heavy proteinuria	12
also examined	12
health behavior	12
also performed	12
positive family	12
also reported	12
studies using	12
basal ganglia	12
raw data	12
high rates	12
recurrent episodes	12
urinary calcium	12
results demonstrate	12
term prognosis	12
overall health	12
direct sequencing	12
provide evidence	12
current research	12
fully understood	12
blood count	12
physical inactivity	12
outcomes among	12
resistance exercise	12
participants aged	12
low education	12
two months	12
cognitive functions	12
treatment options	12
studied patients	12
associated secretory	12
term effects	12
activity level	12
blood urea	12
significant improvements	12
spike protein	12
age may	12
lipid rafts	12
proportional hazard	12
care workers	12
biopsy proven	12
studies will	12
global pandemic	12
enzyme inhibitors	12
plasma levels	12
poorly understood	12
physical functioning	12
specific ige	12
sedentary time	12
per age	12
improved significantly	12
upper limb	12
novel mutation	12
seven countries	12
patient died	12
health disparities	12
generational research	12
introduction background	12
safety profile	12
mediated immunity	12
without significant	12
frozen plasma	12
lifestyle interventions	12
group pathogens	12
health risks	12
oral cyclophosphamide	12
connective tissue	12
inflammatory pathways	12
take place	12
higher number	12
copa syndrome	12
absolute number	12
associated factors	12
bone formation	12
ros production	12
many factors	12
diagnostic tests	12
tertiary care	12
influenza infection	12
clinical findings	12
results will	12
investigated whether	12
afc spatial	12
least months	12
many different	12
mitochondrial cytochrome	12
different groups	12
disease duration	12
year later	12
retrospective case	12
intellectual disability	12
airflow obstruction	12
bone mineral	12
four months	12
human health	12
endothelial cell	12
depression scale	12
children living	12
lipid metabolism	12
cardiac arrest	12
associated changes	12
ten years	12
renal development	12
also measured	12
fresh frozen	12
i will	12
may present	12
mesangial cells	12
chinese population	12
adjusted odds	12
showed mild	12
low level	12
based medicine	12
protective role	12
severe respiratory	12
western countries	12
age structured	12
grounded theory	12
community dwelling	12
mutational analysis	12
healthy volunteers	12
tubular acidosis	12
gender estimation	12
serum total	12
immunosuppressive drugs	12
public intervention	12
inflammatory activity	12
surface expression	12
cleavage activity	12
might also	12
antibody responses	12
host factors	12
muscular dystrophy	12
capacity building	12
based participatory	12
collagen type	12
ill patients	12
control strategies	12
independent living	12
old subjects	12
arterial disease	12
initial evaluation	12
birth cohorts	12
vessel vasculitis	12
many years	12
national institutes	12
based study	12
rs virus	12
aged adults	12
will focus	12
wilms tumor	12
dry weight	12
modulate mitochondrial	12
young non	12
mesangial proliferation	12
medical management	12
red blood	12
study also	12
related atherosclerosis	12
gyeonggi province	12
might lead	12
female ratio	12
old copd	12
data set	12
immunoglobulin levels	12
friendly cities	12
long time	12
new patients	12
may well	12
polycystic kidney	12
health consequences	12
gfr ml	12
older children	12
upper airway	12
reference cohort	12
postoperative complications	12
without evidence	12
spastic paraparesis	12
related loss	12
healthy lifestyle	12
support services	12
partly due	12
treatment strategies	12
latin american	12
mean dose	12
intrinsic capacity	12
incidence among	12
also observed	12
resource utilization	12
schwartz formula	12
aging lung	12
elderly adults	12
may prevent	12
cognitive performance	12
hiv disease	12
clinical immunology	12
ureteric bud	11
diseases including	11
serum samples	11
transplant candidates	11
unclear whether	11
relatively high	11
surveillance data	11
another study	11
allergic diseases	11
activated protein	11
patient education	11
financial support	11
single centre	11
muscle volume	11
endothelial growth	11
studies show	11
functional outcome	11
may differ	11
signalling pathway	11
positive predictive	11
daughter caring	11
communitydwelling older	11
emerging evidence	11
low risk	11
aged people	11
bartter syndrome	11
childhood cancer	11
study indicated	11
department visits	11
housing affordability	11
recent data	11
wide resnet	11
dawley rats	11
obstructive uropathy	11
also evaluated	11
organ dysfunction	11
ethics committee	11
systematic reviews	11
table shows	11
skin test	11
population aging	11
interquartile range	11
diabetes patients	11
studies reported	11
acute stress	11
inflammatory profile	11
thrombotic microangiopathy	11
anthropometric measurements	11
significant clinical	11
will include	11
chronic infection	11
gray matter	11
th cells	11
accelerated aging	11
commons attribution	11
van der	11
cardiac transplantation	11
early phase	11
negative outcomes	11
essential hypertension	11
cell culture	11
sex hormones	11
frail scale	11
propensity score	11
transplanted patients	11
age distributions	11
missense mutations	11
copd subjects	11
routine clinical	11
igd igm	11
primary prevention	11
barr virus	11
degree relatives	11
group received	11
gender difference	11
adults living	11
female patients	11
comorbid conditions	11
normal blood	11
sensitive nephrotic	11
antihypertensive drugs	11
kong government	11
analysis included	11
steroid withdrawal	11
cognitive aging	11
gastroenteritis viruses	11
twelve patients	11
showed similar	11
renal stones	11
cardiovascular health	11
common among	11
subjects aged	11
quadriceps muscle	11
cd ro	11
entering approach	11
steroid resistance	11
obese older	11
calcineurin inhibitors	11
research process	11
based case	11
conservative treatment	11
reproductive health	11
sustainable development	11
twice daily	11
young patients	11
common diseases	11
economic factors	11
severely affected	11
cr ratio	11
hd patients	11
wide variety	11
sarcopenic older	11
royal manchester	11
multicenter study	11
perspective offers	11
pain relief	11
agerelated diseases	11
baseline data	11
patients also	11
higher probability	11
age cohorts	11
least years	11
primary healthcare	11
rate variability	11
venous thrombosis	11
unreported cases	11
social exclusion	11
older veterans	11
around age	11
endothelial dysfunction	11
basic reproduction	11
primary endpoint	11
gene therapy	11
statistical difference	11
mitochondrial stress	11
progressive loss	11
mini nutritional	11
outcome data	11
acute lung	11
daily life	11
incubation period	11
design methods	11
modifiable risk	11
coronavirus infection	11
throughout life	11
icu stay	11
will contribute	11
generational thinking	11
intervention studies	11
bone turnover	11
protective effects	11
tissue injury	11
patients hospitalized	11
age differences	11
term outcomes	11
single dose	11
larger number	11
brachial plexus	11
social inclusion	11
renal injury	11
physical functions	11
immunodeficiency virus	11
ang ii	11
positive association	11
autoimmune cytopenias	11
drug therapy	11
deficient mice	11
varicella zoster	11
cardiovascular system	11
urea nitrogen	11
ventricular hypertrophy	11
rhgh therapy	11
human coronavirus	11
times higher	11
muscle contraction	11
telomerase activity	11
significant morbidity	11
normal population	11
related factors	11
elevated serum	11
stress response	11
crb tbr	11
fi nancial	11
i i	11
high degree	11
young adult	11
people may	11
mathematical models	11
study entry	11
mri scans	11
critical illness	11
tested positive	11
mild cognitive	11
weak social	11
cellular immune	11
control studies	11
th th	11
skin infections	11
month old	11
labour market	11
gray wolves	11
younger respondents	11
especially among	11
predicted ifrs	11
health centres	11
social health	11
telomere shortening	11
medical record	11
physiological changes	11
rate among	11
good health	11
higher proportion	11
pathogenic role	11
liver enzymes	11
immune aging	11
may enhance	11
diagnostic accuracy	11
limited data	11
care professionals	11
oxidative phosphorylation	11
total ige	11
body height	11
systemic inflammatory	11
also contribute	11
mean sd	11
otherwise healthy	11
transcription factors	11
side effect	11
among different	11
controlled study	11
lumbar spine	11
humoral immune	11
urban area	11
journal pre	11
asymptomatic individuals	11
calf circumference	11
social constructions	11
average annual	11
acute care	11
functional ability	11
cystic fibrosis	11
herpes simplex	11
study revealed	11
physical limitations	11
care service	11
past months	11
ambulatory blood	11
human immunodeficiency	11
unwanted sexual	11
main outcome	11
body temperature	11
tobacco smoke	11
conducted using	11
information regarding	11
underlying mechanisms	11
ventricular mass	11
first patient	11
sustained remission	11
kg bw	11
high percentage	11
research agenda	11
missing values	11
free mass	11
serum vitamin	11
also important	11
marrow failure	11
three cases	11
sectional survey	11
mitochondrial membrane	11
mixed infections	11
purpura nephritis	11
congenital anomalies	11
clonal hematopoiesis	11
different stages	11
representative sample	11
positron emission	11
dravet syndrome	11
incident cases	11
antibody levels	11
immune dysfunction	11
tibialis anterior	11
electronic medical	11
genetic diagnosis	11
lower extremities	11
th century	11
useful tool	11
associated infections	11
community capacity	11
left leg	11
climate change	11
world outcomes	11
molecular weight	11
unknown origin	11
mineral density	11
home environment	11
well described	11
plasma creatinine	11
genetic counseling	11
screening program	11
younger generations	11
random forest	11
clinically meaningful	10
generational stereotypes	10
caenorhabditis elegans	10
treatment period	10
findings support	10
publicly available	10
renal toxicity	10
muscle atrophy	10
small sample	10
multiple linear	10
intravascular coagulation	10
mean bmi	10
lessons learned	10
cell cytotoxicity	10
important implications	10
functional outcomes	10
rank test	10