bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
immune responses	351
respiratory syndrome	340
immune response	284
infectious bronchitis	261
influenza vaccine	259
public health	232
acute respiratory	222
severe acute	206
bronchitis virus	204
vaccine development	197
influenza virus	195
influenza vaccination	195
neutralizing antibodies	165
west nile	159
syndrome coronavirus	150
vaccinia virus	143
neutralizing antibody	141
vaccine candidates	133
spike protein	126
dna vaccine	124
vaccine doi	121
cord uid	121
doc id	121
nile virus	117
virus infection	116
antibody response	115
united states	113
respiratory syncytial	111
syncytial virus	110
influenza vaccines	108
amino acid	108
protective immunity	107
clinical signs	107
antibody titers	106
seasonal influenza	104
days post	101
animal models	99
clinical trials	99
vaccine candidate	98
cell responses	97
mtb wcl	95
control group	95
virus vaccine	95
middle east	94
live attenuated	90
immune system	90
clinical trial	89
cell culture	88
influenza viruses	88
infectious diseases	88
east respiratory	87
pandemic influenza	87
cellular immune	86
mvaik rsv	83
antibody responses	82
health care	82
respiratory tract	81
significantly higher	80
otitis media	79
older adults	78
sars coronavirus	76
vaccine efficacy	75
cell line	75
modified vaccinia	75
vesicular stomatitis	75
viral vector	73
avian infectious	73
adverse events	73
age group	72
class i	72
viral rna	72
vaccine safety	72
rift valley	71
disease virus	71
valley fever	71
time pcr	70
vero cells	70
sars vaccine	69
world health	68
mouth disease	68
vaccine strain	67
animal health	67
based vaccine	66
yellow fever	66
serum samples	65
hong kong	65
antibody levels	65
lymph nodes	65
previously described	64
smallpox vaccine	64
age groups	63
viral load	63
immunodeficiency virus	62
protective efficacy	62
vaccination coverage	61
virus type	61
dendritic cells	60
respiratory disease	60
stomatitis virus	60
humoral immune	60
avian influenza	60
working group	58
phase i	58
mhc class	57
monoclonal antibodies	56
cell lines	56
specific igg	56
porcine reproductive	55
vaccinated mice	55
room temperature	54
statistically significant	54
rabies virus	54
live virus	54
present study	54
antibody titres	53
dna vaccines	53
high levels	53
cd cd	52
virus vaccines	52
health organization	51
structural proteins	51
viral replication	51
ck ch	51
negative control	51
developing countries	51
transmissible gastroenteritis	51
nk cells	50
cotton rats	50
vaccine production	50
disease burden	50
siv gag	49
poly iclc	49
healthcare workers	49
income countries	49
protein expression	49
dengue virus	49
mice immunized	48
specific antibodies	48
cell response	48
described previously	48
measles vaccine	48
vaccine effectiveness	48
innate immune	47
recombinant virus	47
virus ankara	47
syndrome virus	47
binding domain	47
based vaccines	47
measles virus	46
inactivated vaccine	46
ebola virus	46
systematic review	45
risk factors	45
embryonated eggs	45
rna replication	45
coronavirus spike	45
monoclonal antibody	45
new zealand	44
human immunodeficiency	44
infected cells	44
vaccinated animals	44
fever virus	44
attenuated vaccine	44
cov infection	44
infectious disease	44
cell epitopes	43
vaccine strains	43
authors declare	42
disease control	42
specific antibody	42
modified live	42
lymph node	42
fusion protein	42
amino acids	42
results showed	42
specific igy	42
visceral leishmaniasis	42
positive control	41
virus strains	41
japanese encephalitis	41
per group	41
mandatory immunization	41
human health	41
viral infection	40
animal model	40
influenza season	40
health centers	40
may also	40
mdck cells	40
inactivated sars	40
mlv mtb	39
influenza pneumonia	39
body weight	39
nucleic acid	39
important role	39
vaccine hesitancy	39
canine parvovirus	39
type i	39
new vaccine	39
protective immune	39
encephalitis virus	39
specific cd	39
time points	38
performed using	38
phase iii	38
fc protein	38
polymerase chain	38
health center	38
confirmed influenza	37
influenza pandemic	37
wild type	37
mouse model	37
nucleocapsid protein	37
ch lhlj	37
respiratory viruses	37
chain reaction	36
escherichia coli	36
like particles	36
mva mers	36
young children	36
molecular weight	36
veterinary medicine	36
vaccine vector	36
recombinant vaccinia	36
significant difference	36
inactivated vaccines	36
attenuated vaccines	36
infectious peritonitis	35
candidate vaccines	35
rna viruses	35
chadox mers	35
bovine serum	35
respiratory infections	35
inactivated virus	35
brighton collaboration	35
flow cytometry	35
previous studies	35
virus challenge	35
epithelial cells	35
years old	35
feline infectious	35
bordetella pertussis	35
novel coronavirus	35
clinical development	34
reverse genetics	34
single dose	34
capsid protein	34
igg antibodies	34
adaptive immune	34
cell fusion	34
virus replication	34
chicken eggs	34
subunit vaccines	33
vaccinia ankara	33
zika virus	33
vaccine coverage	33
human igg	33
vector vaccines	33
vaccine group	33
gem particles	33
adult immunization	33
infectious virus	33
type virus	32
antibody titer	32
insect cells	32
vaccine virus	32
specific immune	32
newcastle disease	32
recombinant protein	32
mouse igg	32
cov spike	32
significant differences	32
subunit vaccine	32
viral infections	32
day post	31
rna virus	31
pcr assays	31
dependent enhancement	31
gene expression	31
virus strain	31
saudi arabia	31
two groups	30
two different	30
significantly lower	30
immunized mice	30
ibv strains	30
new vaccines	30
gastroenteritis virus	30
mammalian cells	30
viral vectors	30
preventable diseases	30
iu ml	30
parainfluenza virus	29
human disease	29
viral titer	29
receptor binding	29
financial interests	29
three times	29
goat anti	29
plasmid dna	29
clinical disease	29
rn protein	29
vsv xn	29
inactivated influenza	29
avian coronavirus	29
lethal challenge	29
vaccine clinical	29
lc mo	29
lyme disease	29
recent years	28
animal diseases	28
complement activation	28
global health	28
western blot	28
sars cov	28
mucosal immunity	28
spike gene	28
eda ese	28
cell lysate	28
acute otitis	28
personal relationships	28
fc fusion	28
like receptor	27
vaccine delivery	27
placebo group	27
current study	27
side effects	27
emerging infectious	27
commercially available	27
advisory committee	27
recombinant measles	27
rsv vaccine	27
passive immunity	27
cho dhfr	27
antibody production	27
cell surface	27
vaccination rates	27
delivery system	27
human primates	27
virus expressing	27
vaccinated groups	26
significant increase	26
blood samples	26
cellular immunity	26
vaccine may	26
tr protein	26
following vaccination	26
vaccine uptake	26
favn assay	26
oral vaccination	26
statistical analysis	26
vaccination uptake	26
phase ii	26
also observed	26
also found	26
ibv vaccine	26
nk cell	26
rsv subgroup	26
attenuated virus	26
challenge virus	25
mononuclear cells	25
pigs vaccinated	25
well plates	25
ibv vaccines	25
sequence analysis	25
significantly reduced	25
candidate vaccine	25
vaccine vectors	25
cervical lymph	25
transgenic mice	25
vaccination program	25
mg ml	25
new caledonia	25
peripheral blood	25
control groups	25
serially diluted	25
disease enhancement	25
poultry industry	25
viral respiratory	25
mucosal immune	24
haemorrhagic disease	24
ad vector	24
vaccinated chickens	24
virus neutralization	24
vaccinated birds	24
field trial	24
spike glycoprotein	24
vaccine manufacturers	24
clinical symptoms	24
vaccinated dogs	24
kunjin replicon	24
pediatric patients	24
two doses	24
smallpox vaccination	24
three groups	24
coronavirus infection	24
blood cells	24
secondary antibody	24
pdm vaccine	24
study period	24
smallpox vaccines	24
post hatch	23
class ii	23
zoonotic diseases	23
herd immunity	23
treatment groups	23
clinical studies	23
coronavirus vaccine	23
ibv vaccinated	23
egg yolk	23
virus infections	23
adherent cells	23
field strains	23
total rna	23
years post	23
spf chickens	23
adjuvanted vaccine	23
mycoplasma bovis	23
enhanced disease	23
red blood	23
presenting cells	23
culture supernatants	23
herpes simplex	23
dna vaccination	23
known competing	23
bhk cells	23
vaccination campaign	22
see table	22
western blotting	22
sars patients	22
oral administration	22
viral proteins	22
cell cultures	22
vector vaccine	22
antibody titre	22
live vaccine	22
among children	22
last years	22
passive transfer	22
serial passage	22
recombinant vesicular	22
work reported	22
disease prevention	22
equine encephalitis	22
sars vaccines	22
years age	22
competing financial	22
serial passages	22
recombinant viruses	22
canine visceral	22
flow cytometric	22
antibiotic use	22
rabies vaccine	22
mpl tdm	22
pregnant women	22
mammalian cell	22
target cells	22
get vaccinated	21
vaccine expressing	21
strand rna	21
upper respiratory	21
humoral immunity	21
guinea pigs	21
dengue vaccine	21
adverse effects	21
highly pathogenic	21
simian immunodeficiency	21
lactogenic immunity	21
ibv challenge	21
veterinary vaccines	21
venezuelan equine	21
factors associated	21
associated disease	21
immune cells	21
high risk	21
cells infected	21
per year	21
controlled trial	21
mycobacterium tuberculosis	21
viral challenge	21
cov vaccine	21
risk group	21
animal studies	21
results indicated	21
stranded rna	21
adenovirus type	21
log reu	21
cell epitope	21
adjuvanted influenza	21
recombinant vsvs	21
associated coronavirus	21
human monoclonal	21
lower respiratory	21
global vaccine	21
adult vaccine	21
time rt	21
ibv vlps	20
diarrhea virus	20
long term	20
binding affinity	20
control calves	20
vaccine acceptance	20
one dose	20
guinea pig	20
observation period	20
effective vaccine	20
replication incompetent	20
tissue culture	20
recombinant vaccine	20
cell activation	20
reverse transcriptase	20
infectious agents	20
cov rbd	20
neutralization titers	20
virus isolation	20
vector system	20
treatment group	20
vaccines may	20
least one	20
influenza infection	20
mandatory vaccination	20
igm antibodies	20
vaccine adverse	20
memory cells	20
action plan	20
human vaccine	20
host range	20
highly attenuated	20
recombinant vsv	20
prrsv specific	20
coronavirus infectious	20
genetically modified	20
severe disease	20
animals vaccinated	20
fusion ability	20
immunization programs	20
simplex virus	20
hendra virus	20
vaccine research	20
cell immunity	20
humoral response	20
mortality rates	20
th cells	19
th responses	19
adverse reactions	19
mediated immunity	19
vaccinated group	19
secreting cells	19
allantoic fluid	19
broiler chicks	19
purified inactivated	19
four groups	19
pertussis vaccines	19
lg ml	19
embryonated chicken	19
vaccination history	19
challenged pigs	19
virus vectors	19
innate immunity	19
national institutes	19
rhesus monkeys	19
live vaccines	19
bovine coronavirus	19
commercial vaccine	19
previously reported	19
risk groups	19
acute phase	19
wide range	19
pcr amplification	19
one week	19
le poly	19
culture medium	19
viral titers	19
acellular pertussis	19
isa cpg	19
rats immunized	19
review editing	19
adult vaccines	19
vaccination programme	19
healthy adults	19
membrane protein	19
pcr assay	19
adult population	19
buffered saline	19
cd cells	18
bd pharmingen	18
tcid ml	18
rabbit haemorrhagic	18
natural infection	18
fetal bovine	18
vaccine antigen	18
product development	18
general population	18
first time	18
results obtained	18
cell lysates	18
reverse transcription	18
prescribing information	18
currently available	18
hepatitis virus	18
streptococcus pneumoniae	18
viruses expressing	18
ciliary activity	18
igg antibody	18
cd ifn	18
future covid	18
pseudotype assay	18
patient information	18
lung tissues	18
safety issues	18
safety profile	18
nonstructural protein	18
humoral responses	18
vaccine supply	18
rabies vaccination	18
viral diseases	18
eu ml	18
human infections	18
acid changes	18
vaccine design	18
effector memory	18
data suggest	18
new york	18
lactococcus lactis	18
memory cd	18
nonhuman primates	18
virus disease	18
risk assessment	18
vaccines based	18
day group	18
determine whether	18
animal care	18
signal peptide	18
mediated immune	18
risk conditions	18
female balb	17
low levels	17
weight loss	17
case study	17
control study	17
similar results	17
collaborative study	17
mass vaccination	17
neutralization test	17
neutralising antibodies	17
respiratory illness	17
vaccine preparation	17
health security	17
human cells	17
determined using	17
standardized template	17
pertussis vaccine	17
serum antibody	17
neutralization titer	17
highly immunogenic	17
effective vaccines	17
vaccine administration	17
tr expression	17
confidence intervals	17
national immunization	17
antigen presenting	17
horseradish peroxidase	17
recombinant adenovirus	17
pulmonary viral	17
herpes zoster	17
influenza vaccinations	17
intranasal administration	17
tract infections	17
bd biosciences	17
vectored vaccines	17
african green	17
vaccine based	17
post challenge	17
genetic stability	17
one health	17
ebola vaccine	17
epidemic diarrhea	17
vaccine formulations	17
ibv ck	17
swine fever	17
united kingdom	17
porcine epidemic	17
among health	17
supplementary data	17
inoculated pigs	17
bcg vaccination	17
vaccination status	16
dromedary camels	16
regulatory approval	16
oral delivery	16
canine rabies	16
genomic rna	16
calf diarrhoea	16
accession number	16
multiplex pcr	16
viral vaccines	16
vaccine alone	16
blood mononuclear	16
logistic regression	16
cell wall	16
fold higher	16
reverse genetic	16
equal volume	16
high level	16
field strain	16
linked immunosorbent	16
induce protective	16
iga antibodies	16
avian metapneumovirus	16
whole cell	16
producing cd	16
coding region	16
immunization program	16
first vaccination	16
high titers	16
cattery cats	16
vectored vaccine	16
electron microscopy	16
vaccinated pigs	16
positive samples	16
analyzed using	16
borne encephalitis	16
fever vaccine	16
open reading	16
drug administration	16
haemophilus influenzae	16
tgev vaccine	16
pathogen free	16
peritonitis virus	16
cytopathic effect	16
ev igy	16
million doses	16
health authorities	16
membrane proteins	16
funded health	16
reported immunity	16
vaccine induced	16
culture supernatant	16
vn antibody	15
older age	15
protective effect	15
previous study	15
specific memory	15
spf chicken	15
pregnant sows	15
vaccinia viruses	15
ex vivo	15
mucosal adjuvant	15
natural killer	15
widely used	15
per dose	15
peptide vaccine	15
care workers	15
whole virus	15
elevated activity	15
mouse anti	15
virus capsid	15
conjugated goat	15
cdna clones	15
nasal spray	15
attenuated influenza	15
binary ethylenimine	15
vaccine will	15
lymphoid tissues	15
previous reports	15
vaccine antigens	15
within days	15
significantly increased	15
real time	15
coronavirus infections	15
sample size	15
foreign genes	15
economic losses	15
weeks post	15
nasal discharge	15
attenuated vaccinia	15
maternal antibodies	15
viral genome	15
i ifn	15
pcr using	15
swinepox virus	15
coronavirus disease	15
will need	15
total population	15
statistical significance	15
samples collected	15
oral vaccine	15
vaccine induces	15
well tolerated	15
mice received	15
mdck cell	15
responses induced	15
viral clearance	15
among hcp	15
virus glycoprotein	15
will require	15
antibiotic resistance	15
news media	15
results indicate	15
purified vaccine	15
geometric mean	15
infected animals	15
influenza epidemics	15
ha gene	15
highly effective	15
safety concerns	15
per well	15
coverage among	15
human use	15
polio vaccine	15
increased frequency	15
recent study	15
elsevier ltd	15
human cases	15
delivery systems	15
antigen presentation	15
rabbit anti	15
viral loads	15
different groups	15
node cells	15
ap vaccines	15
old spf	15
cell mediated	15
coronavirus associated	15
cytokine responses	15
membrane fusion	15
closely related	15
lactis gem	15
sars virus	15
protection conferred	15
increased risk	15
mers coronavirus	15
cd expression	14
health emergency	14
virus particles	14
human mhc	14
safety data	14
attenuated viruses	14
health system	14
mortality rate	14
arboviral diseases	14
spike proteins	14
cloned mdck	14
vaccine use	14
virus vector	14
sars subject	14
every year	14
hi antibody	14
virus isolates	14
north america	14
information leaflet	14
central memory	14
cell tropism	14
may contribute	14
naturally infected	14
taken together	14
vaccine response	14
aged years	14
nipah virus	14
efficacy trials	14
minimal epitope	14
antigen units	14
reporter gene	14
higher levels	14
human vaccines	14
affinity maturation	14
coronavirus ibv	14
infected mice	14
cell populations	14
mm sodium	14
acid sequence	14
vaccination among	14
interstitial pneumonia	14
cell subsets	14
mucosal sites	14
primary care	14
cells ml	14
regulatory agencies	14
vaccine manufacturing	14
single immunization	14
west africa	14
pneumococcal disease	14
center patients	14
adjuvant vaccine	14
potent adjuvant	14
peptide pool	14
past years	14
viral particles	14
specific pathogen	14
dcvmn members	14
significantly different	14
post vaccination	14
mosaic virus	14
like illness	14
animal species	14
host cell	14
challenged mice	14
european union	14
mycobacterium bovis	14
molecular diagnosis	14
medical exemptions	14
vaccines used	14
discrete choice	14
cho cell	14
specific iga	14
antigenic sites	14
field trials	14
lung tissue	14
social media	14
ebola zaire	14
serum igg	14
efficacy studies	14
conjugated anti	14
time point	14
oral bait	14
recent studies	14
coronavirus nucleocapsid	14
elispot assay	14
th response	14
emerging diseases	14
pfu ml	14
human medicine	14
rhesus macaques	14
producing cells	14
molecular epidemiology	14
bronchitis coronavirus	14
viral entry	14
candidate sars	14
challenge studies	14
quality control	14
cytometric analysis	14
day old	13
antimicrobial resistance	13
rights reserved	13
may provide	13
neutralising antibody	13
mucosal immunization	13
virus inactivation	13
kunjin virus	13
beaudette strain	13
attenuated strains	13
human influenza	13
fold dilutions	13
transmissible vaccines	13
different time	13
global public	13
pigs inoculated	13
three cities	13
recombinant human	13
neutralizing activity	13
clinical data	13
ibv vaccination	13
based vectors	13
two weeks	13
graphpad prism	13
european countries	13
adults aged	13
protective effects	13
mammary secretions	13
rotavirus vaccine	13
serial dilutions	13
domesticated animals	13
transfected cells	13
key considerations	13
intranasal delivery	13
siv uptake	13
secondary antibodies	13
field conditions	13
uptake among	13
human population	13
standard error	13
peptide sequence	13
results show	13
kidney cells	13
will also	13
oral polio	13
epidemic preparedness	13
cov strains	13
valent pneumococcal	13
way anova	13
mouse sera	13
expression levels	13
infectious cdna	13
ebola vaccines	13
serum antibodies	13
relatively low	13
san diego	13
may lead	13
standard curve	13
human cd	13
specific neutralizing	13
adult vaccination	13
endoplasmic reticulum	13
cellular responses	13
protein expressed	13
transmissible vaccine	13
gene therapy	13
vero cell	13
vaccine developers	13
tissue tropism	13
inactivation process	13
influenza immunization	13
inflammatory responses	13
based influenza	13
mice vaccinated	13
plasmodium falciparum	13
ebola outbreak	13
vaccine protects	13
secretory iga	13
vaccination may	13
pbl hu	13
neutralisation assays	13
regulatory authorities	13
wild animals	13
peptide pools	13
th immune	13
time period	13
wnv infection	13
lactis cells	13
copy number	13
respiratory virus	13
five mice	13
significant reduction	13
cell monolayers	13
total number	13
well microtiter	13
vaccine evaluation	13
data indicate	13
cold chain	13
complement receptor	13
novel vaccine	13
sf cells	13
vaccinated calves	13
fusion inhibition	13
measured using	13
human services	13
treated mice	13
study showed	13
diphtheria toxoid	12
virus neutralizing	12
cynomolgus macaques	12
igg anti	12
serological responses	12
preventive services	12
central nervous	12
vaccination strategies	12
signal sequence	12
prrsv mn	12
vaccination policy	12
oral immunisation	12
confirmed cases	12
weeks later	12
policy makers	12
bcg vaccine	12
disease incidence	12
virus titers	12
passive immunization	12
mucosal adjuvants	12
pbs containing	12
elispot assays	12
protects mice	12
cell population	12
neonatal calf	12
incubation period	12
considered significant	12
protein concentration	12
kidney samples	12
vaccines expressing	12
domestic animals	12
cell produced	12
nt antibodies	12
vaccination group	12
killer cells	12
vaccination campaigns	12
immunized animals	12
specific ifn	12
clinical manifestations	12
complete protection	12
achieved using	12
universal influenza	12
recombinant dna	12
human clinical	12
rotavirus vaccines	12
mdck pf	12
different doses	12
human adenovirus	12
attribute levels	12
inoculated intranasally	12
human metapneumovirus	12
ive estimates	12
trivalent vaccine	12
lung mnc	12
final concentration	12
influenza activity	12
slightly lower	12
corona virus	12
plasma samples	12
rapid detection	12
cells expressing	12
envelope glycoprotein	12
also reported	12
young infants	12
viral disease	12
days old	12
recovered individuals	12
virus suspension	12
alveolar macrophages	12
existing vaccines	12
corynebacterium parvum	12
specific cytotoxic	12
pathogenic avian	12
risk benefit	12
oral rabies	12
igg titers	12
igm antibody	12
bronchitis viruses	12
results demonstrate	12
nervous system	12
gov identifier	12
newborn calves	12
human rotavirus	12
coding sequence	12
serum albumin	12
systems biology	12
homologous recombination	12
vaccination arrangement	12
parvovirus type	12
major histocompatibility	12
health workers	12
tested positive	12
whole inactivated	12
also showed	12
treated group	12
expressing cells	12
reading frame	12
respiratory diseases	12
spleen cells	12
measles vaccines	12
draining lymph	12
vaccine studies	12
spf eggs	12
veterinary medical	12
one study	12
host cells	12
large scale	12
health professionals	12
cohort study	12
healthy children	12
vaccine constructs	12
per mouse	12
bovis infection	12
bone marrow	12
cov replication	12
adcho cells	12
protein gene	12
like receptors	12
rna polymerase	12
maternal immunization	12
health systems	12
strong immune	12
viral shedding	12
virus transmission	12
expression system	12
replicon rna	12
south america	12
coverage rates	12
vaccine immunogenicity	12
virus genome	12
reference preparations	12
adjuvant effect	12
genome sequence	12
vaccine administered	12
infected patients	12
calculated using	12
commercial broiler	11
recombinant baculovirus	11
virus stock	11
recombinant swinepox	11
pertussis toxin	11
core protein	11
rsv infection	11
economic impact	11
future research	11
risk populations	11
conjugate vaccine	11
secondary bacterial	11
chickens inoculated	11
pig lungs	11
dc replicon	11
adherent fraction	11
infected cell	11
days later	11
neutralizing titers	11
signal peptides	11
adjuvant system	11
per capita	11
pneumococcal conjugate	11
binding ability	11
many countries	11
young calves	11
vaccine dose	11
protect mice	11
immunization practices	11
inflammatory response	11
three weeks	11
information regarding	11
cytokine production	11
serious adverse	11
boost vaccination	11
viral antigens	11
lower levels	11
emerging infections	11
natural host	11
induces protective	11
vaccination groups	11
weight gain	11
purification process	11
old embryonated	11
standard deviation	11
highest dilution	11
quantitative real	11
days prior	11
rates among	11
dna fragments	11
classical swine	11
hi titers	11
challenge model	11
yz strains	11
ng ml	11
strong neutralizing	11
recombinant proteins	11
antibiotic treatment	11
dogs vaccinated	11
without tpa	11
million people	11
neutralizing activities	11
i molecules	11
sequence changes	11
conducted using	11
chickens infected	11
different age	11
sialic acid	11
virus production	11
analysis showed	11
igg isotype	11
virus infected	11
error bars	11
ug ml	11
denv infection	11
lethal dose	11
regulatory cells	11
high mortality	11
vaccine elicits	11
survey participants	11
control mice	11
disease vaccine	11
days postvaccination	11
bl mice	11
institutional animal	11
nasal delivery	11
vaccines will	11
acid substitutions	11
respiratory pathogens	11
viral protein	11
naturally occurring	11
dual route	11
full length	11
pg ml	11
control animals	11
national institute	11
igg fc	11
framework ii	11
optical density	11
causative agent	11
technical assistance	11
relative importance	11
fatality rate	11
potential vaccine	11
per ml	11
propionibacterium acnes	11
region ii	11
th cytokines	11
igm levels	11
faecal samples	11
adaptive immunity	11
children aged	11
another study	11
neutralizing titer	11
term protection	11
may result	11
virus induces	11
bovine viral	11
take siv	11
different approaches	11
much lower	11
vaccines safety	11
vaccination programs	11
immune complexes	11
health impact	11
safety working	11
growth kinetics	11
host population	11
enteric coronavirus	11
tissue samples	11
vector expressing	11
production capacity	11
gag protein	11
vaccination decision	11
virulence factors	11
ctl vaccine	11
rabbit populations	11
igg response	11
surface antigen	11
protein peptides	11
cells well	11
american indian	11
global burden	11
pcr analysis	11
vaccine containing	11
host factors	11
supplementary table	11
vaccine elicited	11
convalescent serum	11
pbs control	11
personalized vaccinology	11
also used	11
informed consent	11
mouse hepatitis	11
attenuated measles	11
bait vaccine	11
pandemic vaccine	11
vlp vaccines	11
infectious particles	11
will likely	11
fusion proteins	11
vector organism	11
hemorrhagic fever	11
nile vaccine	11
mice serum	11
vaccine action	11
genbank accession	11
human immune	11
gross lesions	11
vn titers	10
microtiter plate	10
cell immune	10
treated virus	10
dairy calves	10
chitosan nanoparticles	10
microtiter plates	10
cov challenge	10
cytokine il	10
influenza cases	10
nasal colonization	10
exon splicing	10
adjuvanted vaccines	10
increase vaccination	10
among healthcare	10
food safety	10
vaccine trials	10
may cause	10
health organisation	10
aedes mosquitoes	10
dna sequence	10
sodium phosphate	10
white leghorn	10
case definitions	10
pneumonia patients	10
clinical evaluation	10
incubated overnight	10
inactivated whole	10
infected chickens	10
ad vaccine	10
household income	10
host response	10
biological properties	10
rsv periods	10
region i	10
climate change	10
advisory group	10
wild rabbit	10
public trust	10
vaccination regimen	10
detected using	10
field isolates	10
respondent countries	10
adenovirus vector	10
bacterial pathogens	10
unpublished data	10
well plate	10
adenovirus serotype	10
vaccines containing	10
influenza infections	10
old female	10
two major	10
respiratory infection	10
slightly higher	10
vaccine doses	10
intranasal vaccination	10
also demonstrated	10
developed countries	10
viral pathogens	10
human sera	10
effector cells	10
preventive medicine	10
forming units	10
enhancing effect	10
vaccine approaches	10
microplate reader	10
i clinical	10
trivalent influenza	10
elisa plates	10
length cdna	10
study design	10
measles viruses	10
washed twice	10
recombinant viral	10
annual influenza	10
may require	10
adjuvant systems	10
cleavage site	10
vaccine groups	10
rbd mf	10
regulatory convergence	10
based adjuvant	10
commercial vaccines	10
ad libitum	10
virus neutralisation	10
animal rule	10
large numbers	10
clinical samples	10
many years	10
hpv vaccine	10
rsv subgroups	10
alaska native	10
washed three	10
critical role	10
vaccine prepared	10
years ago	10
protein antigen	10
alkaline phosphatase	10
two years	10
beef herds	10
adventitious agents	10
vaccination probability	10
direct vaccination	10
vaccination location	10
adverse event	10
randomized clinical	10
green monkeys	10
immunized group	10
task force	10
high incidence	10
histocompatibility complex	10
south africa	10
national health	10
intensive care	10
memory responses	10
ampv subtype	10
antigen delivery	10
lung disease	10
veterinary vaccine	10
rbd binding	10
pcr products	10
diagnostic tests	10
pneumococcal vaccination	10
st century	10
fc mf	10
acid sequences	10
using two	10
five days	10
confer protection	10
virulent virus	10
complement receptors	10
positive results	10
cells via	10
ctl epitopes	10
online version	10
groups showed	10
adjuvanted group	10
zikv infection	10
virus shed	10
animal vaccines	10
replication kinetics	10
target population	10
experimental infection	10
six months	10
immunosorbent assay	10
vaccine trial	10
among adults	10
expression vector	10
respiratory viral	10
human serum	10
elisa using	10
vaccine encoding	10
pcr system	10
protective antibody	10
purified rha	10
case fatality	10
group showed	10
neutralisation assay	10
fip cases	10
inactivated ibv	10
nucleotide sequence	10
circulating ifn	10
arrangement procedure	10
laboratory animal	10
virus growth	10
activity periods	10
malaria vaccine	10
ifn signaling	10
pf cells	10
experimental conditions	10
indian alaska	10
human coronavirus	10
perceived risk	10
igg titres	10
including vaccines	10
vaccine cross	9
vaccines induced	9
like virus	9
human pathogens	9
envelope protein	9
simultaneous detection	9
clinical specimens	9
rabies vaccines	9
randomized controlled	9
disease severity	9
veterinary research	9
combination vaccines	9
mucosal iga	9
medically attended	9
wild animal	9
one group	9
kb region	9
molecular characterization	9
mice per	9
international collaborative	9
whole genome	9
cell expression	9
systemic immunity	9
type vaccine	9
previous infection	9
well known	9
vlp vaccine	9
outer membrane	9
attenuated strain	9
pcr positive	9
vaccine used	9
total igg	9
sectional study	9
high dose	9
colleagues intending	9
may play	9
iii trials	9
phase clinical	9
pt igg	9
intranasal immunization	9
mlv alone	9
vaccinated cows	9
novel recombinant	9
least two	9
fmd vaccine	9
virus core	9
vaccine preventable	9
based subunit	9
nm nm	9
services administration	9
available vaccines	9
samples tested	9
investigate whether	9
supplementary material	9
disease vaccines	9
health research	9
oral immunization	9
endemic area	9
rabies dna	9
product labeling	9
flavivirus infection	9
potential impact	9
infectious agent	9
specific anti	9
randomly selected	9
yz strain	9
vaccines administered	9
bovine rotavirus	9
serum dilution	9
respiratory coronavirus	9
total protein	9
choice experiment	9
antibodies induced	9
even though	9
two types	9
use committee	9
deficient mice	9
ovo vaccination	9
highest antibody	9
emc strain	9
antibody assays	9
igg levels	9
competing interests	9
th type	9
important factor	9
target cell	9
old group	9
fisher scientific	9
lister strain	9
ribyz strain	9
several vaccines	9
pathogen areas	9
mrna vaccines	9
kindly provided	9
ampv vaccinated	9
viral growth	9
cytoplasmic domain	9
heat shock	9
leading cause	9
leader sequence	9
bacillus calmette	9
received gb	9
chronic diseases	9
virus envelope	9
disease following	9
phase proteins	9
vaccine preparations	9
serum institute	9
response elicited	9
table shows	9
barr virus	9
efficacy study	9
also induced	9
current status	9
phase trials	9
nonstructural proteins	9
large number	9
mice developed	9
week intervals	9
health resources	9
better understand	9
expression plasmid	9
original draft	9
relatively high	9
virus titer	9
dengue hemorrhagic	9
polio eradication	9
vaccine immunity	9
splicing enhancers	9
intranasal route	9
virus induced	9
immune complex	9
virus recombinant	9
institutional review	9
protein vaccine	9
may help	9
part i	9
meningococcal meningitis	9
excess prescriptions	9
based tgev	9
older adult	9
middle income	9
health problems	9
samples taken	9
significantly associated	9
th th	9
healthy volunteers	9
blot analysis	9
trial sites	9
igy treated	9
primary vaccination	9
excess mortality	9
three consecutive	9
small intestine	9
short time	9
nucleic acids	9
using reverse	9
results suggest	9
cpg adjuvant	9
several studies	9
vaccine recipients	9
neutralization assay	9
rbd sera	9
phosphate buffered	9
regulatory pathways	9
younger age	9
bacterial infections	9
mucosal surfaces	9
neuronal necrosis	9
aedes aegypti	9
world bank	9
pseudovirus neutralization	9
dairy herds	9
negative design	9
cells per	9
data associated	9
passive protection	9
guangdong province	9
control serum	9
studies suggest	9
single vaccination	9
broiler chickens	9
disease caused	9
observed daily	9
total cell	9
reported cases	9
surveillance system	9
one hundred	9
dependent immune	9
two influenza	9
phase iib	9
murine model	9
first immunization	9
key stakeholders	9
saponin vaccine	9
complement system	9
one sample	9
sectional survey	9
plaque reduction	9
gene sequences	9
intramuscular injection	9
stimulation index	9
developing vaccines	9
virus detection	9
protein formulated	9
ibv infection	9
neutralization antibody	9
experimental vaccine	9
benefit assessment	9
coronavirus vaccines	9
ensemble modeling	9
virus vaccination	9
fc immunized	9
double stranded	9
vectors expressing	9
data demonstrate	9
dose vaccine	9
expanded programme	9
based recombinant	9
elevated levels	9
working groups	9
rna recombination	9
flavivirus cps	9
review board	9
product characteristics	9
manufacturing process	9
surveillance data	9
field virus	9
challenged group	9
experimental group	9
cells using	9
serum sample	9
murine antisera	9
licensed vaccine	9
pertussis antigens	9
hiv gag	9
see text	9
alveolar damage	9
polyclonal antibodies	9
co incubator	9
publicly available	9
enhanced respiratory	9
following challenge	9
mean titer	8
chronic lung	8
murine coronavirus	8
improve vaccine	8
reported pertussis	8
immunization group	8
study group	8
th cytokine	8
plasminogen activator	8
ctl responses	8
recombinant myxoma	8
primary immunization	8
fluorescence intensity	8
target product	8
newly discovered	8
probably due	8
induced protection	8
influenza among	8
cell entry	8
culture media	8
immunized monkeys	8
efficacy trial	8
strategic advisory	8
chicken embryos	8
developing world	8
hu mice	8
must also	8
youngest age	8
brain tissues	8
blocking buffer	8
foreign gene	8
population groups	8
care personnel	8
recombinant strain	8
promising vaccine	8
rabbits inoculated	8
cytopathic effects	8
healthy individuals	8
pneumococcal vaccine	8
recombinant sars	8
unvaccinated controls	8
tissue plasminogen	8
higher level	8
body temperature	8
binding protein	8
global action	8
virus recovery	8
inserted genes	8
mf group	8
future outbreaks	8
infection rate	8
regression model	8
novel vaccines	8
recombinant vp	8
virus used	8
virus isolated	8
purified sars	8
polysaccharide vaccine	8
rational design	8
evidence suggests	8
vpd control	8
childhood vaccination	8
positive cells	8
essential role	8
old broiler	8
clinical features	8
using anti	8
cell receptor	8
high yielding	8
enveloped virus	8
associated mortality	8
tlr agonist	8
lesser extent	8
adventitious viruses	8
available data	8
scientific knowledge	8
vaccine given	8
experimental animals	8
primary vaccinees	8
low cost	8
attenuated live	8
confidence interval	8
quantitative virology	8
preliminary results	8
found online	8
new developments	8
national vaccine	8
antibiotic prescriptions	8
coronavirus neutralization	8
mers vaccines	8
urgent need	8
fcov antibody	8
various time	8
life cycle	8
trial design	8
adult focus	8
sequence data	8
cmi response	8
month period	8
provide protection	8
murine hepatitis	8
suppressor cells	8
transmission cycle	8
remains unclear	8
chemically inactivated	8
please provide	8
ace cells	8
global pandemic	8
clinical applications	8
rbd protein	8
gag gene	8
signal sequences	8
elongation rate	8
preparedness innovations	8
influenza periods	8
three major	8
mm tris	8
oral immunisations	8
th percentile	8
dendritic cell	8
nuclear localization	8
peptide complex	8
provided protection	8
cber criteria	8
ciliostasis scores	8
antibodies directed	8
rna genome	8
live recombinant	8
mm nacl	8
leishmania infantum	8
laboratory tests	8
previously shown	8
sanofi pasteur	8
vg ga	8
ml pbs	8
first week	8
also help	8
porcine respiratory	8
antiviral activity	8
human cell	8
laboratory conditions	8
vaccination messages	8
pathogens including	8
egg produced	8
cell vaccine	8
inactivated rsv	8
fold serial	8
diagnostic assays	8
type ibv	8
developed using	8
higher neutralizing	8
differences among	8
experimental challenge	8
cdna clone	8
phylogenetic trees	8
total serum	8
dengue viruses	8
inoculated chickens	8
trivalent inactivated	8
first year	8
lessons learned	8
animal vaccination	8
adjuvanted treatment	8
take rates	8
specific secondary	8
animal reservoir	8
response may	8
sendai virus	8
combination vaccine	8
specific humoral	8
vaccinal strains	8
medical center	8
rabbit igg	8
pathological changes	8
adult patients	8
heterologous prime	8
vaccine viruses	8
lymphocyte subsets	8
different species	8
vaccine formulation	8
avian flu	8
chickens vaccinated	8
ev infection	8
neutralizing epitopes	8
nested pcr	8
mucosal vaccine	8
children ages	8
dna encoding	8
high income	8
virus rna	8
type vsv	8
severe cases	8
cellular immunogenicity	8
different virus	8
health policy	8
animal populations	8
virus specific	8
health officials	8
virus identification	8
restriction sites	8
rna transcripts	8
sera obtained	8
vaccine adjuvants	8
animal human	8
cell function	8
large proportion	8
brome mosaic	8
calf serum	8
fold increase	8
protein contains	8
severe outcomes	8
necessarily represent	8
elisa assay	8
prime immunization	8
preclinical development	8
nucleotide sequences	8
virus stocks	8
among pediatric	8
igy treatment	8
clinical protection	8
chicken embryo	8
small number	8
medium containing	8
also developed	8
mh promoter	8
laboratory parameters	8
virus encephalitis	8
disease surveillance	8
yz group	8
two days	8
gb specific	8
effective protection	8
research institute	8
cell proliferation	8
systemic immune	8
drug delivery	8
recombinant vaccines	8
i i	8
emergency vaccines	8
regulatory agency	8
study vaccines	8
research council	8
emphasis framing	8
elderly adults	8
medical research	8
uptake rate	8
maternal antibody	8
neonatal pigs	8
southern china	8
growth medium	8
day vaccinated	8
proteins expressed	8
excess deaths	8
improving health	8
induced immune	8
per million	8
human complement	8
molecular biology	8
per chick	8
surface proteins	8
pet cats	8
sputum samples	8
stomatitis viruses	8
terminal region	8
inflammatory cytokines	8
highly contagious	8
elisa kit	8
health services	8
acute viral	8
previous work	8
i ii	8
human papillomavirus	8
related hospitalization	8
viral antigen	8
antigen dose	8
day vaccination	8
maternally derived	8
broad spectrum	8
viral vaccine	8
third vaccination	8
minor groove	8
expression systems	8
cellular receptor	8
nasal route	8
serum protein	8
total igy	8
manufacturing capacity	8
infectious clone	8
first isolated	8
randomly divided	8
genomic sequence	8
large amounts	8
virus showed	8
commonly used	8
cell pools	8
state university	8
rbd proteins	8
pandemic preparedness	8
indirect elisa	8
ad hdpp	8
cats showed	8
adjuvant activity	8
thermo fisher	8
field isolate	8
mucosal vaccines	8
fc receptor	8
vaccine using	8
biological characteristics	8
pneumococcal polysaccharide	8
edmonston strain	8
ml recombinant	8
statistical analyses	8
primary health	8
tested negative	8
myxoma virus	8
vaccine information	8
rapid development	8
immunization strategies	8
mandatory elements	8
pandemic vaccines	8
signaling pathway	8
growth curves	8
virus proteins	8
influenza illness	8
neonatal diarrhoea	8
saharan africa	8
avidity index	8
previously vaccinated	8
five weeks	8
potential use	8
case studies	8
virus may	8
community engagement	8
using different	8
mucosal vaccination	8
bcg induced	8
studies using	8
nw adherent	8
emerging pathogens	8
regulatory criteria	8
one animal	8
human dpp	8
per day	8
influenza strains	8
three months	8
respiratory tracts	7
high binding	7
young pet	7
vaccines include	7
vaccine regimen	7
biomedical research	7
adenylate cyclase	7
total volume	7
immunization schedule	7
elicit protective	7
severe respiratory	7
safe vaccine	7
receptor type	7
milk antibody	7
week old	7
groove binder	7
new smallpox	7
will allow	7
proinflammatory cytokines	7
injected animals	7
pbs group	7
virus concentration	7
cell death	7
immunological assays	7
virulent ibv	7
test samples	7
ctl epitope	7
dpp receptor	7
human host	7
rna vaccines	7
multimethods study	7
beaudette strains	7
borne diseases	7
developing new	7
lung pathology	7
heat killed	7
data obtained	7
higher frequency	7
last century	7
vaccination trial	7
first days	7
preventive care	7
one year	7
ibv strain	7
vertical coordinate	7
vaccination arguments	7
military population	7
analysis using	7
center patient	7
protein induces	7
pdvac meeting	7
respiratory distress	7
arkdpi vaccine	7
vivo rna	7
genetic diversity	7
clinical course	7
international standard	7
pac i	7
incubation time	7
gene encoding	7
bp intron	7
data collection	7
conjugated secondary	7
mild signs	7
sr proteins	7
also noted	7
human transmission	7
prrsv challenged	7
ha protein	7
three samples	7
group received	7
regression models	7
become available	7
clinical characteristics	7
ml penicillin	7
endemic areas	7
veterinary practice	7
clinical scores	7
immunogenicity data	7
cystic fibrosis	7
mer peptide	7
transmissible protection	7
flu vaccination	7
live sars	7
chitosan derivatives	7
different serotypes	7
free medium	7
fcov infection	7
clinical chemistry	7
highly specific	7
new ap	7
mers vaccine	7
perfect cross	7
boost immunization	7
general public	7
chronic conditions	7
four times	7
like strain	7
high vaccination	7
vaccination schedule	7
mandatory influenza	7
vaccines using	7
molecular mechanism	7
pseudotype assays	7
among different	7
zoonotic disease	7
titres achieved	7
vaccine licensure	7
strain used	7
warp speed	7
specific human	7
sense rna	7
clinical testing	7
different live	7
new cases	7
approximately one	7
biological standards	7
provides protection	7
elderly people	7
ebola vaccination	7
south african	7
different methods	7
placebo controlled	7
one way	7
much higher	7
united nations	7
induces sars	7
polio vaccines	7
genetically engineered	7
us government	7
rna transcript	7
vnab titres	7
hiv vaccine	7
rabies glycoprotein	7
assay using	7
control measures	7
inducing protective	7
oral cholera	7
inflammatory cytokine	7
fmd virus	7
attenuated smallpox	7
porcine transmissible	7
urgently needed	7
factors influencing	7
table i	7
see section	7
experimental animal	7
mucosal immunisation	7
vaccine components	7
recent research	7
antigen processing	7
point mutations	7
annual production	7
healthy aging	7
challenge groups	7
preventing human	7
attenuated vsv	7
flavivirus vaccines	7
vaccine markets	7
i study	7
high rates	7
effective means	7
gag dx	7
systemic igg	7
cell activity	7
containing vaccines	7
cows vaccinated	7
immune protection	7
higher igg	7
murine antiserum	7
vaccine compared	7
cv vaccine	7
times higher	7
vesicular lesions	7
new england	7
sedimentable particles	7
vaccines targeting	7
assays using	7
intron addition	7
ii clinical	7
target antigen	7
vaccination programmes	7
using specific	7
challenge study	7
effective strategy	7
prime boost	7
virus field	7
virus entry	7
old embryos	7
transduced mice	7
birds vaccinated	7
early vaccination	7
significantly greater	7
five chicks	7
protease inhibitor	7
post auricular	7
flow cytometer	7
income level	7
technology transfer	7
passaged virus	7
children hospitalized	7
passage virus	7
national regulatory	7
mediated protection	7
showed high	7
reactive antibodies	7
antibodies specific	7
denv cp	7
associated lymphoid	7
seven days	7
vaccinated individuals	7
arkga vaccine	7
nasal mucosa	7
rna vaccine	7
will continue	7
vaccine delivered	7
fold lower	7
higher risk	7
online survey	7
induces protection	7
development efforts	7
showed seroconversion	7
health concern	7
adjuvant effects	7
indirect immunofluorescence	7
matrix protein	7
lethal infection	7
protein expressing	7
currently used	7
highly efficient	7
fmd vaccines	7
severe adverse	7
significantly less	7
poisson model	7
pcr methods	7
healthcare professionals	7
safety evaluation	7
tracheas removed	7
vector systems	7
dependent manner	7
transgene expression	7
statin use	7
following immunization	7
danger signals	7
mouse models	7
inactivation protocols	7
different vsvs	7
contextual factors	7
sars corona	7
mucosal antibody	7
binding site	7
new infectious	7
light microscope	7
inactivation rate	7
second half	7
ampv vaccine	7
mosquito vectors	7
high prevalence	7
towards vaccination	7
tests performed	7
heterologous virus	7
oil adjuvant	7
milk samples	7
poorly immunogenic	7
orally administered	7
antigen expression	7
marburg virus	7
year period	7
endothelial cells	7
padlock probes	7
log tcid	7
purified rn	7
studies showed	7
i interferon	7
healthcare personnel	7
protein concentrations	7
vsvs expressing	7
immunosorbent assays	7
vaccine showed	7
formaldehyde inactivation	7
collaboration viral	7
gene gun	7
two distinct	7
position paper	7
vaccination services	7
immunity following	7
may prove	7
molecular beacons	7
showed higher	7
vaccination choice	7
siv mac	7
splicing enhancer	7
general adult	7
close contact	7
human cytomegalovirus	7
will lead	7
healthy human	7
cells may	7
pertussis infection	7
ii study	7
dry pharynx	7
inactivation procedures	7
bacterial pneumonia	7
newly emerging	7
pediatric health	7
international reference	7
increased levels	7
successful vaccination	7
broad range	7
tlr agonists	7
time reverse	7
virulent strains	7
process development	7
pathogenic field	7
reduction neutralization	7
green fluorescent	7
test groups	7
complete genome	7
younger adults	7
temperature sensitivity	7
eid per	7
scan statistic	7
rna stability	7
protein antigens	7
expressing rsv	7
avf full	7
tropical medicine	7
literature review	7
dose regimen	7
contingent valuation	7
public perceptions	7
simple method	7
virulent challenge	7
cytotoxicity assay	7
plate reader	7
graphpad software	7
capsid gene	7
glycoprotein gene	7
billion people	7
human diseases	7
horizontal transmissible	7
embryonated spf	7
sac ii	7
framing theory	7
rsv antigen	7
tcid per	7
human dose	7
wcl inoculated	7
helper cells	7
vaccinated chicks	7
fetal calf	7
antiviral drugs	7
neonatal calves	7
generation vaccine	7
virus hemagglutinin	7
sera collected	7
tracheal rales	7
appropriate animal	7
active surveillance	7
like particle	7
high proportion	7
acid vaccines	7
patient survey	7
rotavirus infections	7
cell clones	7
serum neutralization	7
uk government	7
vaccines encoding	7
currently licensed	7
two times	7
four different	7
potent neutralization	7
induced humoral	7
elisa plate	7
ts phenotype	7
public acceptance	7
vaccinations among	7
cilia beating	7
immune enhancement	7
recombinant modified	7
virus nucleocapsid	7
vaccine manufacture	7
tract infection	7
biosafety level	7
immunosuppressed rabbits	7
health departments	7
transgenic mouse	7
display system	7
mouse serum	7
cd foxp	7
previously unknown	7
old chicks	7
mouse monoclonal	7
diluted mouse	7