Questions

This is a list of all the questions and their associated study carrel identifiers. One can learn a lot of the "aboutness" of a text simply by reading the questions.

identifier question
cord-001116-2yvyiiuyDo multiple outcome measures require p- value adjustment?
cord-001675-9717nzr7: implications for pandemic influenza preparedness Do viral infections mimic bacterial sepsis?
cord-001829-rwnbxmt4or alfa-2a with ribavirin for treatment of hepatitis C infection Deciphering the interleukin 28B variants that better predict response to pegylated interferon- alpha and ribavirin therapy in HCV/ HIV-1 coinfected patients Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance Genome- wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus AU- rich elements and associated factors: are there unifying principles?
cord-001901-2s6hpakkToll- like receptor 10 is involved in induction of innate immune responses to influenza virus infection Differential role of TLR- and RLR- signaling in the immune responses to influenza A virus infection and vaccination Innate immune responses to influenza A H5N1: friend or foe?
cord-002490-kw8psrmzHow do filovirus filaments bend without breaking?
cord-004181-exbs3tz7The Journal of Infectious Diseases Development of Streptococcus agalactiae vaccines for tilapia Streptococcal β protein has separate binding sites for human factor h and IgA- Fc Identification of group B streptococcal Sip protein, which elicits cross- protective immunity Immunotherapy of established( pre)malignant disease by synthetic long peptide vaccines A web resource for designing subunit vaccine against major pathogenic species of bacteria Prospects for control of emergimg infectious dyseases with plasmid DNA vaccines DNA vaccines: ready for prime time?
cord-003490-swlkjtyoYea or nay?
cord-002019-wtnf340pThe postnatal development of the mucosal immune system and mucosal tolerance in domestic animals How informative is the mouse for human gut microbiota research?
cord-001823-v60vv99oA methodology for performing global uncertainty and sensitivity analysis in systems biology American Ebola Quarantine Zones Will Be Genocidal Death Traps How many people infected with ebola die?
cord-001823-v60vv99oReport-25 Ebola vaccination: if not now, when?
cord-002659-566uoozjCell pellets were resuspended in PBS and stained with fluorescein isothiocyanate( FITC)-conjugated anti- CD4( BD Biosciences) and allophycocyanin( APC)-conjugated anti- CD8( BD Biosciences) antibodies; erythrocytes were lysed by the addition of FACS Lysing Solution Epidemiology of 2009 pandemic influenza A( H1N1) deaths in the United States Factors associated with death or hospitalization due to pandemic 2009 influenza A( H1N1) infection in California Fatal cases associated with pandemic influenza A( H1N1) reported in Greece Does glycosylation as a modifier of original antigenic sin explain the case age distribution and unusual toxicity in pandemic novel H1N1 influenza?
cord-003196-fdb6az0vCD14 mediate response to respiratory syncytial virus Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke Effect of carbon dioxide on neonatal mouse lung: a genomic approach Histone chaperones in nucleosome assembly and human disease Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway Histone H2A variants in nucleosomes and chromatin: more or less stable?
cord-003055-88q36g00Developmental neuroinflammation and schizophrenia Schizophrenia and autism: both shared and disorder- specific pathogenesis via perinatal inflammation?
cord-004150-ybikajhhHow many biological replicates are needed in an RNA- seq experiment and which differential expression tool should you use?
cord-004385-xna32qveThe initial intentions of corticosteroid therapy were unclear( was it used as a rescue therapy or due to COPD/ asthma exacerbation or due to pneumonia/ ARDS?).
cord-002673-5a1rfi6kHowever, notwithstanding such promising genetic selection opportunities, there are substantial knowledge gaps about the genetic diversity of NNV among Asian grouper hosts: are there many strains within and between regions, perhaps with different virulence so that each region or NNV strain may then require different selection programs, or not?
cord-002673-5a1rfi6kMoreover, is there evidence that NNV strains vary over time?
cord-004379-91a7sgirinfluenza A virus Can Disproportionality Analysis of Post- marketing Case Reports be Used for Comparison of Drug Safety Profiles?
cord-003444-dmpoy0b1These findings raise the question of can NEI display similar adjuvant activity for vaccines given through other mucosal routes and, possibly non- mucosal vaccines?
cord-004310-hl7fa4af: Is it really different?
cord-002290-wvo22jx2For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection Innate immune gene polymorphisms in tuberculosis Mannan- binding lectin deficiency- Good news, bad news, does n't matter?
cord-002290-wvo22jx2another case of heterosis?
cord-002844-jv42o789Chromatin remodeling, histone modifications, and DNA methylation- how does it all fit together?
cord-002844-jv42o789is the eIF4E cap- binding factor required for viral mRNA translation?
cord-002411-iiw878w8Has mortality from acute respiratory distress syndrome decreased over time?
cord-002411-iiw878w8Signaling The mercurial nature of neutrophils: still an enigma in ARDS?
cord-011892-b9zlig0rIs my network module preserved and reproducible?
cord-002474-2l31d7ewWhy, when and how do HVAC- systems pollute the indoor environment and what to do about it?
cord-010328-uxpedpz8The re- emergence of measles in developed countries: Time to develop the next- generation measles vaccines?
cord-004016-iaktm72amodified silver nanoparticles for highly efficient inhibition of respiratory syncytial virus infection Effect of Encapsulation of Curcumin in Polymeric Nanoparticles: How Efficient to Control ESIPT Process?
cord-034746-uxhpufnvmellitus Soluble urokinase plasminogen activator receptor is a predictor of incident non- AIDS comorbidity and all- cause mortality in human immunodeficiency virus type 1 infection Modification of kidney barrier function by the urokinase receptor What is the role of soluble urokinase- type plasminogen activator in renal disease?
cord-012742-lpk6r54iHow good are my data and what is the resolution?
cord-255586-wshvvgxgWill we see protection or reinfection in COVID-19?
cord-003505-qr6ukftiDiagnosis of Parasitic Infections: What's Going On?
cord-002802-594mmlk8humans Molecular characterization of H9N2 influenza viruses: were they the donors of the"internal"genes of H5N1 viruses in Hong Kong?
cord-010140-nl1j2s56The key question is therefore, what is the mechanism of anti- PfRipr antibodies on parasite growth inhibition?
cord-001868-utsvsja0The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza Influenza- induced innate immunity: regulators of viral replication, respiratory tract pathology& adaptive immunity Role of host cellular proteases in the pathogenesis of influenza and influenza- induced multiple organ failure Molecular pathogenesis of influenza A virus infection and virus- induced regulation of cytokine gene expression Induction of proinflammatory cytokines in human macrophages by influenza A( H5N1) viruses: a mechanism for the unusual severity of human disease?
cord-002758-d86hnox1Did tRNA synthetase classes arise on opposite strands of the same gene?
cord-002758-d86hnox1Is there a relationship between DNA sequences encoding peptide ligands and their receptors?
cord-002758-d86hnox1application to the"gene nursery"of deltaretroviruses Evolution of living organisms: evidence for a new theory of transformation Is genetic code redundancy related to retention of structural information in both dna strands?
cord-271602-f14wccj3Does weather confound or modify the association of particulate air pollution with mortality?
cord-004419-81w7apdk25- 28 weeks gestation Current practice in early management of neonatal respiratory distress syndrome: Is it evidence- based?
cord-004222-z4butywipriming a broadly neutralizing antibody response to HIV-1 using a germline targeting immunogen Identification of common features in prototype broadly neutralizing antibodies to HIV envelope V2 apex to facilitate vaccine design High- throughput immune repertoire analysis with IGoR Estimating the population size for capture- recapture data with unequal catchability How many different clonotypes do immune repertoires contain?
cord-004060-nxw5k9y1: What Are the Lessons for Influenza Vaccination?
cord-004060-nxw5k9y1Bayesian estimates of disease maps: how important are priors?
cord-265891-jmpterrjwhat next?
cord-272576-ez731lifIf a common directional change is observed, what types of changes likely reoccur in future epidemics caused by invasions from natural reservoir hosts?
cord-276444-jidvkij5Tom70 mediates Sendai virus- induced apoptosis on mitochondria Respiratory syncytial virus infection sensitizes cells to apoptosis mediated by tumor necrosis factor- related apoptosis- inducing ligand MAP kinases and cell migration Mitogen- activated protein kinase phosphatase 1 as an inflammatory factor and drug target Regulation of innate immune response by MAP kinase phosphatase-1 MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids?
cord-005507-equnyib7: Attempt at an Inventory Immunogenomic screening approach to identify new antigens for the serological diagnosis of chronic Chagas'disease Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc- CTL-1 and Tc- TES-26 Global burden of cancers attributable to infections in 2012: a synthetic analysis Infection as a cause of type 1 diabetes?
cord-005507-equnyib7: Is It Time for a Change?
cord-293747-ds8rhbkvA Potentially Emerging Epidemic?
cord-286559-y8z0pwgnWalking along the rabies genome: is the large G- L intergenic region a remnant gene?
cord-269270-i2odcsx7x- rays with deep learning Can ai help in screening viral and covid-19 pneumonia?
cord-259794-6qoksn00A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling Nucleophosmin and cancer friends or foes?
cord-259794-6qoksn00The nucleolus-a gateway to viral infection?
cord-302080-fegcf1fuThe impact of differential antiviral immunity in children and adults Infant alveolar macrophages are unable to effectively contain Mycobacterium tuberculosis Comparative immune response in children and adults with H. pylori infection contrasting adult and infant immune responses to HIV infection and vaccination The Immune System of Children: The Key to Understanding SARS- CoV-2 Susceptibility?
cord-312777-5925lvueA report of 1014 cases Diagnosis of the coronavirus disease( COVID-19): rRT- PCR or CT?
cord-031937-qhlatg84Clostridium difficile: an under- recognized cause of reactive arthritis?
cord-031937-qhlatg84how do classical and non- classical HLA alleles modulate immune response to human immunodeficiency virus and hepatitis C virus infections?
cord-269756-tid8a464At this concentration, what are the changes in the structural dynamics, curvature and hydration of the lipids and in the thermodynamic parameters of the membranes that lead to membrane fusion?
cord-269756-tid8a464a hairpin Structure and function of membrane fusion peptides Are fusion peptides a good model to study viral cell fusion?
cord-293505-1t3hg4wiHome care for patients with Middle East respiratory syndrome coronavirus( MERS- CoV) infection presenting with mild symptoms and management of contacts?
cord-294220-ewp1m8jpCan bioactive lipids inactivate coronavirus( COVID-19)?
cord-255511-nk3iyg07Identifying Epidemic Patterns Associated with Superspreading Events in Stochastic Models Are the different layers of a social network conveying the same information?
cord-255511-nk3iyg07Is a bustling train station in a central business district more or less susceptible and vulnerable as compared to teeming bus interchanges in the suburbs?
cord-286413-a7wue2e3What to expect for COVID-19?
cord-305473-w30hsr4mThe global burden of respiratory disease Early administration of oral oseltamivir increases the benefits of influenza treatment Treat or test first?
cord-305031-9ze0097wHow to integrate this finding in timetable design, and balance punctuality against the comfort of the passengers that would need to transfer between two more punctual trains?
cord-308302-5yns1hg9Which are most important for predicting outcome?
cord-303601-o8uk6if2what lessons have we learned?
cord-289932-dsysiefxA( Ile- Pro- Ile) and diprotin B( Val- Pro- Leu) inhibitors or substrates of dipeptidyl peptidase IV?
cord-316983-h4mtpcycVenom proteins from parasitoid wasps and their biological functions Diversity of virus- like particles in parasitoids'venom: viral or cellular origin?
cord-284582-xwedgllwBut does this cfDNA have a physiological role?
cord-284582-xwedgllwThis raises the following question: What is the fundamental role of cfDNA in healthy organisms?
cord-280334-7b7rvr25Could the new rabbit haemorrhagic disease virus variant( RHDVb) be fully replacing classical RHD strains in the Iberian Peninsula?
cord-280334-7b7rvr25Is the new variant RHDV replacing genogroup 1 in Portuguese wild rabbit populations?
cord-254653-4ffuivilPart 2-social and political challenges: 2.1 western democracy in crisis??
cord-254653-4ffuivilPart 2-social and political challenges: 2.1 western democracy in crisis??
cord-254653-4ffuivilWhat types of COVID-19 conspiracies are populated by twitter bots?
cord-004418-08dljap3Does Heterologous Flavivirus Immunity Enhance Zika Disease?
cord-004418-08dljap3What Have We Learned from Animal Models?
cord-004418-08dljap3What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans?
cord-296562-3h2oqb9k: A nationwide analysis Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
cord-296562-3h2oqb9kWhy tocilizumab could be an effective treatment for severe COVID-19? Pathogenic T cells and inflammatory monocytes incite inflammatory storm in severe COVID-19 patients
cord-325657-s2vdazq0( Diptera: Muscidae) to transmit Rift Valley fever virus Nonviremic transmission of West Nile virus Nonviremic transmission of West Nile virus: evaluation of the effects of space, time, and mosquito species Is nonviremic transmission of West Nile virus by Culex mosquitoes( Diptera: Culicidae) nonviremic?
cord-288451-npefpo3tA comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special?
cord-288451-npefpo3tBat rotaviruses in humans?
cord-343302-g9vcchrhthe beginning of another SARSlike pandemic?
cord-318187-c59c9vi3Can we use CFD to improve targeted drug delivery in throat?
cord-318187-c59c9vi3The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction Assessment of the influence factors on nasal spray droplet velocity using phase- doppler anemometry External characteristics of unsteady spray atomization from a nasal spray device Measurements of droplet size distribution and analysis of nasal spray atomization from different actuation pressure Automated actuation of nasal spray products: Determination and comparison of adult and pediatric settings On point vortex models of exotic bluff body wakes Exploring the dynamics of'2P'wakes with reflective symmetry using point vortices On the motion of two point vortex pairs with glide- reflective symmetry in a periodic strip Dynamics of vortices in complex wakes: modeling, analysis, and experiments A mathematical model of 2P and 2C vortex wakes On angled bounce- off impact of a drop impinging on a flowing soap film What is normal nasal airflow?
cord-331775-iaxkfszq: what is the current state of the art?
cord-334228-n69iewmxwhen multiple strategies for enzyme activity regulation are available?
cord-339973-kj56zi59Specifically, we asked, could noninvasive bioaerosol sampling detect respiratory viruses in Singapore's MRT network?
cord-344344-q32b742aWhat is the fundamental ion- specific series for anions and cations?
cord-342676-ykog278jvitro RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae Interaction of hepatitis C virus core protein with viral sense RNA and suppression of its translation Selective binding of hepatitis C virus core protein to synthetic oligonucleotides corresponding to the 5′ untranslated region of the viral genome Specific in vitro association between the hepatitis C viral genome and core protein Detection of Cellular Proteins and Viral Core Protein Interacting with the 5′ Untranslated Region of Hepatitis C Virus RNA Role of RNA structures in genome terminal sequences of the hepatitis C virus for replication and assembly Down- regulation of the internal ribosome entry site( IRES)-mediated translation of the hepatitis C virus: critical role of binding of the stem- loop IIId domain of IRES and the viral core protein Hepatitis C virus RNA: molecular switches mediated by long- range RNA- RNA interactions?
cord-342782-xty16m8wSevere Community- Acquired Pneumonia Caused by Human Adenovirus in Immunocompetent Adults: A Multicenter Case Series Severe Infections with Human Adenovirus 7d in 2 Adults in Family Etiology of severe pneumonia in Ecuadorian children Severe community- acquired adenovirus pneumonia treated with oral ribavirin: a case report Antiadenovirus drug discovery: potential targets and evaluation methodologies Repurposing of Anticancer Drugs for the Treatment of Bacterial Infections Drug Repurposing: New Treatments for Zika Virus Infection?
cord-350957-10wcqgaqMultichain immune recognition receptor signaling: different players, same game?
cord-340781-z348xbn0Worldwide burden of cancer attributable to HPV by site, country and HPV type Estimate of the global burden of cervical adenocarcinoma and potential impact of prophylactic human papillomavirus vaccination HPV vaccination: the promise& problems Pros, cons, and ethics of HPV vaccine in teens- Why such controversy?
cord-299605-j1ewxk4qThe malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum Is Plasmodium vivax malaria a severe malaria?
cord-356027-ckdx56j1Cui bono?
cord-329155-ddpfox68Could intermittent energy restriction and intermittent fasting reduce rates of cancer in obese, overweight, and normal- weight subjects?
cord-329155-ddpfox68The connection for cancer therapy?
cord-322486-qwl7nzkr, China Are children less susceptible to COVID-19?
cord-322486-qwl7nzkrWhy are dengue virus serotypes so distantly related?
cord-321667-jkzxjk54The early history of infectious bronchitis Global distributions and strain diversity of avian infectious bronchitis virus: a review Characterization of turkey coronavirus from turkey poults with acute enteritis Identification of a novel coronavirus from a beluga whale by using a panviral microarray Discovery of a novel bottlenose dolphin coronavirus reveals a distinct species of marine mammal coronavirus in Gammacoronavirus Viral respiratory diseases( ILT, aMPV infections, IB): are they ever under control?
cord-321667-jkzxjk54Why do RNA viruses recombine?
cord-342122-certy2v8Still's disease: Evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three centers Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers Life- threatening complications of adult- onset Still's disease Adult haemophagocytic syndrome Reaching the threshold: A multilayer pathogenesis of macrophage activation syndrome Macrophage activation syndrome in the era of biologic therapy Macrophage activation syndrome: Different mechanisms leading to a one clinical syndrome Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: Toward new therapeutic targets?
cord-342122-certy2v8Toward new therapeutic targets?
cord-302459-grs2x26lDoctors'approaches to PSA testing and overdiagnosis in primary healthcare: a qualitative study Time trends and local variation in primary treatment of localized prostate cancer Prostate cancer biomarkers: Are we hitting the mark?
cord-302459-grs2x26lRe: The prostate specific antigen era in the United States is over for prostate cancer: what happened in the last 20 years?
cord-302459-grs2x26lSynthetic essentiality of chromatin remodelling factor CHD1 in PTEN- deficient cancer ProsCan for men: randomised controlled trial of a decision support intervention for men with localised prostate cancer Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer Stability of Circulating Blood- Based MicroRNAs-Pre- Analytic Methodological Considerations Potential pitfalls in microRNA profiling Normalization strategies for microRNA profiling experiments: a'normal'way to a hidden layer of complexity?
cord-302459-grs2x26lcell- cell communication function?
cord-324696-htx0ul4oCurrent opinion in virology Middle East respiratory syndrome coronavirus in bats, Saudi Arabia Bats as'special'reservoirs for emerging zoonotic pathogens Bats are a major natural reservoir for hepaciviruses and pegiviruses Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses?
cord-324696-htx0ul4oMass extinctions, biodiversity and mitochondrial function: are bats'special'as reservoirs for emerging viruses?
cord-324696-htx0ul4oWhile the role of bats in IAV evolution is not yet known, recent evidence raises a primary question,"can bats support co- infection of avian and human IAVs?".
cord-308687-wrzzb9cyCanada( ECCC)'s import restrictions on salamanders Will trade bans stop a deadly salamander plague from invading the US?
cord-308687-wrzzb9cyThe question in this paper is therefore: can pooling swab samples or using eDNA place routine surveillance in reach?
cord-308687-wrzzb9cyTrends in US imports of amphibians in light of the potential spread of chytrid fungus,( Bd), and implications for conservation Qualitative risk analysis of introducing Batrachochytrium dendrobatidis to the UK through the importation of live amphibians Can environmental dna be used for aquatic biosecurity in the aquarium fish trade To pool or not to pool?
cord-308687-wrzzb9cyhow can global spread be prevented?
cord-265211-a7whyds8Can induction of miR-36 by KSHV infection prevent infected cells from being superinfected with KSHV and other related herpesviruses, in vivo?
cord-265211-a7whyds8Does it physically bind KSHV envelope- associated protein and facilitate endocytosis?
cord-265211-a7whyds8How does IFITM1 enhance KSHV infection of cells?
cord-265211-a7whyds8If that is the case, how can IFITM1 enhance infection of not just KSHV; but also of EBV and HSV-2?
cord-265211-a7whyds8What is the dynamics between the expression pattern of IFITM1 and 3 in regulating KSHV infection of cells?
cord-265211-a7whyds8What is the role of host cell receptors in the IFITM1-facilitated virus entry?
cord-338588-rc1h4drdChemotherapy in the treatment of Leukemia and Wilms'tumor Women in academic medicine leadership: has anything changed in 25 years?
cord-338588-rc1h4drdHow has healthcare research performance been assessed?
cord-338588-rc1h4drdThe gender gap in peer- reviewed publications by physical therapy faculty members: a productivity puzzle Comparison of evidence of treatment effects in randomized and nonrandomized studies Can the pharmaceutical industry reduce attrition rates?
cord-338588-rc1h4drdWhy are n't there more women leaders in academic medicine?
cord-326868-3az13h1hA new standardized paradigm to assess trust in romantic relationships Heuristics guide the implementation of social preferences in one- shot Prisoner's Dilemma experiments Does telling white lies signal pro- social preferences?
cord-326868-3az13h1hBut is helping you worth the risk?
cord-326868-3az13h1hCan someone's task- free neurophysiological processing reveal information on someone's prosociality?
cord-326868-3az13h1hGo/ NoGo task performance Brain- to- brain synchronization across two persons predicts mutual prosociality Are strong empathizers better mentalizers?
cord-326868-3az13h1hHow can we interpret the association of microstate A's coverage with prosociality based on previous research examining the functional significance of the four canonical EEG resting networks( for reviews, see 20, 31)?
cord-326868-3az13h1hWhen is giving an impulse?