This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.
trigram | frequency |
---|---|
supplementary figure s | 249 |
the presence of | 240 |
as well as | 142 |
in the presence | 135 |
the number of | 114 |
structure of the | 102 |
human immunodeficiency virus | 91 |
end of the | 89 |
shown in figure | 86 |
supplementary table s | 84 |
of the rna | 83 |
a and b | 82 |
the role of | 81 |
one of the | 79 |
analysis of the | 79 |
figure a and | 73 |
the absence of | 66 |
c for min | 66 |
based on the | 65 |
data not shown | 65 |
in addition to | 64 |
the use of | 63 |
in this study | 63 |
due to the | 63 |
nucleic acids res | 62 |
acids res doi | 62 |
in order to | 62 |
in the absence | 61 |
of the protein | 58 |
downstream of the | 57 |
immunodeficiency virus type | 57 |
the end of | 56 |
as shown in | 55 |
the amount of | 54 |
dependent rna polymerase | 52 |
hepatitis c virus | 52 |
programmed ribosomal frameshifting | 52 |
can be used | 50 |
and supplementary figure | 50 |
in the human | 50 |
at c for | 50 |
was used to | 50 |
of the two | 48 |
acute respiratory syndrome | 47 |
severe acute respiratory | 47 |
is required for | 47 |
activity of the | 47 |
figure s a | 47 |
in figure a | 47 |
on the other | 47 |
crystal structure of | 46 |
b and c | 46 |
the effect of | 46 |
compared to the | 46 |
the ability of | 46 |
such as the | 45 |
figure b and | 45 |
the efficiency of | 45 |
according to the | 45 |
the other hand | 44 |
consistent with the | 44 |
it has been | 44 |
used as a | 44 |
a set of | 44 |
of the stem | 44 |
the majority of | 43 |
the human genome | 43 |
present in the | 43 |
a number of | 43 |
of the s | 42 |
as previously described | 42 |
stability of the | 42 |
been shown to | 42 |
the stop codon | 42 |
the structure of | 42 |
ribosomal frameshifting in | 41 |
of ribosomal frameshifting | 41 |
the sukh superfamily | 40 |
of the p | 40 |
be used to | 40 |
that of the | 40 |
we found that | 40 |
each of the | 40 |
the expression of | 40 |
the s rrna | 39 |
of the ribosome | 39 |
expression of the | 39 |
part of the | 39 |
in supplementary table | 39 |
at room temperature | 38 |
characterization of the | 38 |
nucleic acids research | 37 |
region of the | 37 |
is consistent with | 37 |
was added to | 37 |
of the human | 37 |
conflict of interest | 37 |
the formation of | 37 |
for h at | 37 |
g s in | 37 |
was used as | 37 |
was carried out | 37 |
of interest statement | 37 |
at nar online | 36 |
the ability to | 36 |
available at nar | 36 |
role of the | 36 |
a role in | 36 |
the importance of | 36 |
the slippery sequence | 35 |
observed in the | 35 |
in the case | 35 |
for min at | 35 |
the development of | 35 |
that can be | 34 |
the case of | 34 |
upstream of the | 34 |
a variety of | 34 |
of the homomorph | 34 |
at the end | 34 |
are available at | 34 |
the context of | 33 |
similar to the | 33 |
s and s | 33 |
supplementary data are | 33 |
data are available | 33 |
in which the | 33 |
of g s | 33 |
has been shown | 33 |
there is a | 33 |
of the sukh | 32 |
the addition of | 32 |
in vitro and | 32 |
to determine the | 32 |
surface of the | 32 |
figure s b | 32 |
as described previously | 32 |
an rna pseudoknot | 31 |
of the hiv | 31 |
of the frameshift | 31 |
suggest that the | 31 |
a series of | 31 |
were used to | 31 |
c for s | 31 |
position of the | 31 |
of the viral | 31 |
added to the | 30 |
a subset of | 30 |
figure c and | 30 |
of sf asf | 30 |
of the genome | 30 |
the size of | 30 |
the activity of | 29 |
structural basis for | 29 |
the human immunodeficiency | 29 |
were carried out | 29 |
in the context | 29 |
rna secondary structure | 29 |
is important for | 29 |
the slippery site | 28 |
the fact that | 28 |
d r t | 28 |
found in the | 28 |
pan et al | 28 |
resulted in a | 28 |
the level of | 28 |
presence of a | 28 |
in figure b | 28 |
of fs m | 28 |
the length of | 28 |
in the same | 28 |
specific and non | 28 |
of the same | 28 |
binding to the | 28 |
a and a | 27 |
in contrast to | 27 |
it is possible | 27 |
respiratory syndrome coronavirus | 27 |
the ratio of | 27 |
was found to | 27 |
to that of | 27 |
by the exosome | 27 |
size of the | 27 |
found to be | 27 |
the effects of | 26 |
unfolded protein response | 26 |
followed by a | 26 |
the detection of | 26 |
and characterization of | 26 |
have shown that | 26 |
mutations in the | 26 |
of the motif | 26 |
in response to | 26 |
levels of frameshifting | 26 |
corresponding to the | 26 |
the position of | 26 |
d and d | 26 |
formation of the | 26 |
the mechanism of | 25 |
reading frame maintenance | 25 |
thermo fisher scientific | 25 |
the production of | 25 |
in escherichia coli | 25 |
of the first | 25 |
we show that | 25 |
showed that the | 25 |
function of the | 25 |
the stability of | 25 |
c and d | 25 |
of the mrna | 25 |
regions of the | 24 |
the identification of | 24 |
are shown in | 24 |
the interaction between | 24 |
of an rna | 24 |
the sequences of | 24 |
was incubated with | 24 |
structure of a | 24 |
a function of | 24 |
relative to the | 24 |
as a result | 24 |
derived from the | 24 |
involved in the | 24 |
for min and | 24 |
infectious bronchitis virus | 23 |
materials and methods | 23 |
the interaction of | 23 |
and function of | 23 |
to determine whether | 23 |
in agreement with | 23 |
in the a | 23 |
in the first | 23 |
of the pseudoknot | 23 |
virus variation resource | 23 |
use of a | 23 |
we observed that | 23 |
the fraction of | 23 |
to assess the | 23 |
between the two | 23 |
in mammalian cells | 23 |
mutational analysis of | 22 |
the synthesis of | 22 |
open reading frame | 22 |
frameshifting in the | 22 |
presence of the | 22 |
sequence of the | 22 |
in the p | 22 |
performed as described | 22 |
min at c | 22 |
insights into the | 22 |
well as the | 22 |
of the n | 22 |
of nucleic acids | 22 |
the frameshift site | 22 |
the digital array | 22 |
of the wt | 22 |
were incubated with | 22 |
k ay a | 22 |
were used for | 22 |
is involved in | 22 |
the csl exosome | 22 |
some of the | 22 |
as a function | 22 |
we sought to | 21 |
figure e and | 21 |
assays were performed | 21 |
of the most | 21 |
of the sars | 21 |
shown to be | 21 |
to be a | 21 |
as described in | 21 |
referred to as | 21 |
most of the | 21 |
base of the | 21 |
located in the | 21 |
the viral genome | 21 |
members of the | 21 |
in saccharomyces cerevisiae | 21 |
when compared to | 21 |
suggests that the | 21 |
a negative control | 21 |
results showed that | 21 |
identified in the | 21 |
a role for | 21 |
ribosomal frameshifting signal | 21 |
amino acid sequence | 21 |
used in the | 21 |
the reading frame | 21 |
the results of | 21 |
depending on the | 21 |
suggesting that the | 20 |
be due to | 20 |
activity of vp | 20 |
can also be | 20 |
were able to | 20 |
is shown in | 20 |
and in vivo | 20 |
identification of a | 20 |
length of the | 20 |
are involved in | 20 |
polymerase chain reaction | 20 |
ribosomal protein l | 20 |
close to the | 20 |
there is no | 20 |
the concentration of | 20 |
appears to be | 20 |
revealed that the | 20 |
the function of | 20 |
data indicate that | 20 |
copy number of | 20 |
mediated isothermal amplification | 20 |
in the mrna | 20 |
the existence of | 20 |
were found to | 20 |
a total of | 20 |
and in the | 20 |
carried out in | 20 |
was performed using | 20 |
to interact with | 20 |
of human immunodeficiency | 20 |
the shift site | 20 |
in the cytoplasm | 19 |
than that of | 19 |
of the target | 19 |
of nucleic acid | 19 |
nsp and nsp | 19 |
effect on the | 19 |
the u a | 19 |
in the hiv | 19 |
figure s c | 19 |
of viral proteins | 19 |
are listed in | 19 |
responsible for the | 19 |
supplementary figures s | 19 |
codon in the | 19 |
large number of | 19 |
the frequency of | 19 |
interacts with the | 19 |
were treated with | 19 |
included in the | 19 |
to identify the | 19 |
a u a | 19 |
rna and dna | 19 |
specific amplification events | 19 |
the rate of | 19 |
listed in supplementary | 19 |
a wide range | 19 |
coronavirus ribosomal frameshifting | 19 |
the discovery of | 19 |
has been reported | 19 |
of the slippery | 19 |
final concentration of | 19 |
stop codon readthrough | 19 |
we observed a | 19 |
interact with the | 19 |
mm hepes ph | 19 |
secondary structure of | 19 |
of the wild | 19 |
c and c | 18 |
of the non | 18 |
of the hairpin | 18 |
abundance of the | 18 |
were determined by | 18 |
were purchased from | 18 |
wide range of | 18 |
in the cell | 18 |
g s are | 18 |
the specificity of | 18 |
of s rrna | 18 |
an important role | 18 |
used in this | 18 |
were transfected with | 18 |
a combination of | 18 |
to this end | 18 |
formation of a | 18 |
the wt and | 18 |
the base of | 18 |
of gene expression | 18 |
of the three | 18 |
addition to the | 18 |
the in vitro | 18 |
the uga codon | 18 |
rna polymerase ii | 18 |
room temperature for | 18 |
e and f | 18 |
structures in the | 18 |
were performed as | 18 |
structures of the | 18 |
residues in the | 18 |
play a role | 18 |
as a negative | 18 |
show that the | 18 |
identity of the | 18 |
of the stop | 18 |
all of the | 18 |
which is a | 18 |
were used as | 18 |
were obtained from | 18 |
the firefly luciferase | 18 |
the influence of | 18 |
the virus variation | 18 |
the possibility that | 18 |
side of the | 17 |
at least one | 17 |
indicating that the | 17 |
the exterior surface | 17 |
activation of the | 17 |
absence of the | 17 |
mcm s u | 17 |
bip and chop | 17 |
of a coronavirus | 17 |
of escherichia coli | 17 |
adjacent to the | 17 |
to improve the | 17 |
frameshifting in hiv | 17 |
is composed of | 17 |
cells were treated | 17 |
have been identified | 17 |
in a single | 17 |
in the sample | 17 |
is one of | 17 |
with or without | 17 |
s in the | 17 |
cells treated with | 17 |
we find that | 17 |
of the full | 17 |
the sars coronavirus | 17 |
t m non | 17 |
in this case | 17 |
mutation of the | 17 |
by addition of | 17 |
this suggests that | 17 |
effect of the | 17 |
thermodynamic stability of | 17 |
context of the | 17 |
in terms of | 17 |
synthesis of the | 17 |
specificity of the | 17 |
west nile virus | 17 |
component of a | 17 |
the interaction with | 17 |
the a site | 17 |
the impact of | 17 |
of the ese | 17 |
segment of the | 17 |
vitro and in | 17 |
is possible that | 17 |
the distribution of | 16 |
results indicate that | 16 |
the l p | 16 |
as described above | 16 |
is essential for | 16 |
buffer containing mm | 16 |
cells were transfected | 16 |
the frameshift efficiency | 16 |
the de novo | 16 |
is based on | 16 |
binds to the | 16 |
the surface of | 16 |
the open access | 16 |
the combination of | 16 |
the cells were | 16 |
is responsible for | 16 |
to the p | 16 |
of the a | 16 |
is able to | 16 |
in cell culture | 16 |
results in a | 16 |
polyacrylamide gel electrophoresis | 16 |
incubated at c | 16 |
for the interaction | 16 |
in reading frame | 16 |
of the nsp | 16 |
of the ebov | 16 |
in vitro transcription | 16 |
the t m | 16 |
structure and function | 16 |
nt in length | 16 |
changes in the | 16 |
to test whether | 16 |
of the g | 16 |
in the spacer | 16 |
of rna pseudoknot | 16 |
version of the | 16 |
using the same | 16 |
majority of the | 16 |
multiple sequence alignment | 16 |
note that the | 16 |
could not be | 16 |
is that the | 16 |
in figure c | 16 |
sequences in the | 16 |
sequences of the | 16 |
in the s | 16 |
the levels of | 15 |
it appears that | 15 |
to the reference | 15 |
that the ntd | 15 |
of the gag | 15 |
have been shown | 15 |
the unfolded protein | 15 |
in the database | 15 |
have also been | 15 |
exterior surface of | 15 |
of the ntd | 15 |
were cloned into | 15 |
comparison of the | 15 |
interaction with the | 15 |
the active site | 15 |
translational frameshifting in | 15 |
described in the | 15 |
increasing concentrations of | 15 |
of saccharomyces cerevisiae | 15 |
melting curve analysis | 15 |
we conclude that | 15 |
the template tunnel | 15 |
ii iii iv | 15 |
and can be | 15 |
member of the | 15 |
on the mrna | 15 |
trna in the | 15 |
the secondary structure | 15 |
was determined by | 15 |
the ltr promoter | 15 |
together with the | 15 |
replication and transcription | 15 |
carried out using | 15 |
national center for | 15 |
a lack of | 15 |
the observation that | 15 |
the involvement of | 15 |
the ntd of | 15 |
activity of nsp | 15 |
identification of the | 15 |
result in a | 15 |
of the mcm | 15 |
dna and rna | 15 |
the identity of | 15 |
associated with the | 15 |
a result of | 15 |
duchenne muscular dystrophy | 15 |
is known to | 15 |
are known to | 15 |
as determined by | 15 |
out of the | 15 |
are consistent with | 15 |
was provided by | 15 |
it is not | 15 |
the binding of | 15 |
importance of the | 15 |
role in the | 15 |
of the sequence | 15 |
specific amplification in | 15 |
component of the | 14 |
presence or absence | 14 |
one or more | 14 |
has not been | 14 |
due to a | 14 |
previous studies have | 14 |
or absence of | 14 |
we were able | 14 |
a coronavirus ribosomal | 14 |
at the exterior | 14 |
determined by the | 14 |
was performed with | 14 |
of the gene | 14 |
center for biotechnology | 14 |
clef zinc finger | 14 |
funding to pay | 14 |
detected in the | 14 |
results suggest that | 14 |
two types of | 14 |
u mis assays | 14 |
pay the open | 14 |
indicate that the | 14 |
the bloom filter | 14 |
are required for | 14 |
of the large | 14 |
contrast to the | 14 |
the regulation of | 14 |
interactions between the | 14 |
murine leukemia virus | 14 |
a large number | 14 |
indicated that the | 14 |
important role in | 14 |
s a and | 14 |
in the literature | 14 |
lys mcm s | 14 |
a slippery sequence | 14 |
r r correspondence | 14 |
identical to the | 14 |
sequence and structure | 14 |
degradation of the | 14 |
interactions with the | 14 |
mcm s uuu | 14 |
stop codon in | 14 |
as described earlier | 14 |
on the same | 14 |
ranging from to | 14 |
a final concentration | 14 |
of the bacterial | 14 |
as a template | 14 |
sg mrna transcription | 14 |
from a single | 14 |
in the yeast | 14 |
rna secondary structures | 14 |
for an rna | 14 |
strand rna viruses | 14 |
because of the | 14 |
open access publication | 14 |
the sequence of | 14 |
the analysis of | 14 |
csfv ns b | 14 |
for a given | 14 |
western blot analysis | 14 |
incubated for min | 14 |
fraction of fs | 14 |
total rna was | 14 |
were used in | 14 |
to investigate the | 14 |
in both the | 14 |
trna lys mcm | 14 |
were grown in | 14 |
in frameshift efficiency | 14 |
hek t cells | 14 |
is important to | 14 |
ratio of the | 14 |
shown in supplementary | 14 |
to pay the | 14 |
u a u | 14 |
with ml of | 14 |
viral g s | 14 |
their ability to | 14 |
a decrease in | 14 |
of hepatitis c | 14 |
the replication of | 14 |
locked nucleic acid | 14 |
high levels of | 14 |
we have developed | 14 |
nature of the | 14 |
a j mice | 14 |
and stored at | 14 |
to form a | 14 |
the presence or | 13 |
the possibility of | 13 |
was performed by | 13 |
it can be | 13 |
to the a | 13 |
were subjected to | 13 |
found that the | 13 |
of pip a | 13 |
of the e | 13 |
volume of ml | 13 |
charges for this | 13 |
to have been | 13 |
that in the | 13 |
rna chaperone activity | 13 |
used as the | 13 |
be used as | 13 |
at synonymous sites | 13 |
was shown to | 13 |
data suggest that | 13 |
differences in the | 13 |
the toprim domain | 13 |
for this article | 13 |
the archaeal exosome | 13 |
herpes simplex virus | 13 |
at the c | 13 |
destabilizing activity of | 13 |
at c and | 13 |
resulting in a | 13 |
influenza a virus | 13 |
ese in exon | 13 |
was performed as | 13 |
the reference genome | 13 |
it would be | 13 |
to study the | 13 |
for biotechnology information | 13 |
of protein synthesis | 13 |
indicates that the | 13 |
of the database | 13 |
listed in table | 13 |
remains to be | 13 |
is used to | 13 |
the homomorph is | 13 |
the rna polymerase | 13 |
was observed in | 13 |
provided by the | 13 |
increase in the | 13 |
in the viral | 13 |
was performed in | 13 |
that there is | 13 |
required for efficient | 13 |
are likely to | 13 |
quality control of | 13 |
table and supplementary | 13 |
the nature of | 13 |
in the genome | 13 |
and supplementary table | 13 |
related to the | 13 |
the a u | 13 |
the range of | 13 |
viral replication and | 13 |
of sars coronavirus | 13 |
access publication charges | 13 |
a and c | 13 |
a mixture of | 13 |
were synthesized by | 13 |
during translation of | 13 |
total number of | 13 |
we propose that | 13 |
u a heptamer | 13 |
of a novel | 13 |
h at c | 13 |
t rna polymerase | 13 |
of rna pseudoknots | 13 |
in exon of | 13 |
of chemical probes | 13 |
studies have shown | 13 |
presence of template | 13 |
publication charges for | 13 |
programmed translational frameshifting | 13 |
is present in | 13 |
our understanding of | 13 |
of the sirna | 13 |
caused by the | 13 |
shown that the | 13 |
for s and | 13 |
its ability to | 13 |
were performed using | 13 |
acts as a | 13 |
transfected with a | 12 |
a stop codon | 12 |
c for h | 12 |
with the same | 12 |
in the past | 12 |
used to identify | 12 |
linked to the | 12 |
was used in | 12 |
cell leukemia virus | 12 |
firefly luciferase gene | 12 |
have the same | 12 |
the hepatitis c | 12 |
of the c | 12 |
the ese in | 12 |
gene and protein | 12 |
mechanism of action | 12 |
need to be | 12 |
of the downstream | 12 |
the target cell | 12 |
were incubated at | 12 |
the first step | 12 |
the cyp d | 12 |
we demonstrate that | 12 |
it is likely | 12 |
identification and characterization | 12 |
more than one | 12 |
in the final | 12 |
that sirt is | 12 |
exogenous expression of | 12 |
of the uga | 12 |
yeast saccharomyces cerevisiae | 12 |
used for the | 12 |
cyp d gene | 12 |
led to a | 12 |
we note that | 12 |
this article was | 12 |
are important for | 12 |
some of these | 12 |
cells were seeded | 12 |
elements in the | 12 |
portion of the | 12 |
the final assay | 12 |
role for the | 12 |
whom correspondence should | 12 |
of the virus | 12 |
decrease in the | 12 |
see also supplementary | 12 |
observed that the | 12 |
article was provided | 12 |
conformation of the | 12 |
the ntd and | 12 |
the lack of | 12 |
is highly conserved | 12 |
the terminal loop | 12 |
was used for | 12 |
the highly conserved | 12 |
solution structure of | 12 |
ability of the | 12 |
and analysis of | 12 |
is mediated by | 12 |
orta et al | 12 |
by the presence | 12 |
the total number | 12 |
the mrna and | 12 |
at least in | 12 |
ifn induction by | 12 |
these data indicate | 12 |
pred balb c | 12 |
features of the | 12 |
inhibition of the | 12 |
in most cases | 12 |
to whom correspondence | 12 |
is associated with | 12 |
cells transfected with | 12 |
the removal of | 12 |
inhibition of hiv | 12 |
to address this | 12 |
the predicted stem | 12 |
luciferase assay system | 12 |
of sg mrna | 12 |
observed with the | 12 |
the study of | 12 |
in human cells | 12 |
site of the | 12 |
has been proposed | 12 |
leukemia virus type | 12 |
of figure a | 12 |
would like to | 12 |
terminal loop of | 12 |
the beginning of | 12 |
of g ligands | 12 |
cells were grown | 12 |
depends on the | 12 |
should be addressed | 12 |
t m of | 12 |
we have shown | 12 |
appear to have | 12 |
ml of the | 12 |
amplification in the | 12 |
of viral rna | 12 |
affected by the | 12 |
the hypothesis that | 12 |
the cleavage site | 12 |
binding of the | 12 |
interaction of the | 12 |
was able to | 12 |
presence of g | 12 |
of the exosome | 12 |
genes in the | 12 |
the control of | 12 |
correspondence should be | 12 |
lack of the | 12 |
of the shift | 12 |
of fs z | 12 |
the lacz gene | 12 |
the antisense strand | 12 |
demonstrated that the | 12 |
the amino acid | 12 |
the as rs | 12 |
site and the | 12 |
terminal segment of | 12 |
that have been | 12 |
location of the | 11 |
in this work | 11 |
at least three | 11 |
it is important | 11 |
in vitro translation | 11 |
is supported by | 11 |
residues of the | 11 |
or in the | 11 |
of the primers | 11 |
figure s e | 11 |
the ribosomal a | 11 |
of the corresponding | 11 |
we used the | 11 |
stem of the | 11 |
were analyzed by | 11 |
was confirmed by | 11 |
may play a | 11 |
the degradometer software | 11 |
long terminal repeat | 11 |
required for the | 11 |
by western blotting | 11 |
performed using the | 11 |
our results showed | 11 |
have been used | 11 |
an increase in | 11 |
system for studying | 11 |
de novo initiation | 11 |
amino acid residues | 11 |
ribosomal frameshifting by | 11 |
pcr products were | 11 |
the crystal structure | 11 |
open reading frames | 11 |
dependent rna polymerases | 11 |
have developed a | 11 |
in complex with | 11 |
of the original | 11 |
and the c | 11 |
and evolution of | 11 |
the degradation of | 11 |
was performed on | 11 |
by the viral | 11 |
at the base | 11 |
encoded by the | 11 |
is likely to | 11 |
supplementary tables s | 11 |
of the mirna | 11 |
of messenger rna | 11 |
have been found | 11 |
study of the | 11 |
in figure d | 11 |
treated with mm | 11 |
could be used | 11 |
was purchased from | 11 |
the process of | 11 |
synonymous site conservation | 11 |
with the exosome | 11 |
correlation between the | 11 |
expression levels of | 11 |
coronavirus infectious bronchitis | 11 |
of the ribosomal | 11 |
higher than the | 11 |
extracted from the | 11 |
but not the | 11 |
ribosomal pausing during | 11 |
allowed us to | 11 |
complementary to the | 11 |
the large subunit | 11 |
figure d and | 11 |
of the x | 11 |
quadruplex structures in | 11 |
the ribosome to | 11 |
essential for the | 11 |
structure and mechanism | 11 |
plays an important | 11 |
figure and supplementary | 11 |
is in the | 11 |
active site closure | 11 |
small interfering rna | 11 |
s target genes | 11 |
the rna binding | 11 |
efficiency of the | 11 |
r t and | 11 |
in tissue culture | 11 |
we used a | 11 |
rna was extracted | 11 |
of the conserved | 11 |
located at the | 11 |
be involved in | 11 |
in supplementary figure | 11 |
the binding site | 11 |
are able to | 11 |
mhc class i | 11 |
uga stop codon | 11 |
have been described | 11 |
codons in the | 11 |
of a single | 11 |
is predicted to | 11 |
to the s | 11 |
sequence and the | 11 |
in recent years | 11 |
is similar to | 11 |
mouse hepatitis virus | 11 |
of the coronavirus | 11 |
part of a | 11 |
two or more | 11 |
for the detection | 11 |
slippery sequence and | 11 |
of the rdrp | 11 |
is critical for | 11 |
been reported to | 11 |
can be found | 11 |
in the vicinity | 11 |
of the yeast | 11 |
the location of | 11 |
observations suggest that | 11 |
in the ntc | 11 |
similar to that | 11 |
likely to be | 10 |
we reasoned that | 10 |
protease inhibitor cocktail | 10 |
high t m | 10 |
the cirv genome | 10 |
which is the | 10 |
explanation of rna | 10 |
the percentage of | 10 |
like to thank | 10 |
over the past | 10 |
in the following | 10 |
have been reported | 10 |
to trigger ifn | 10 |
sukh superfamily genes | 10 |
see supplementary table | 10 |
a recent study | 10 |
of the base | 10 |
of the correct | 10 |
the sukh domain | 10 |
in accordance with | 10 |
in an rna | 10 |
the local stability | 10 |
edge of the | 10 |
may be a | 10 |
the severe acute | 10 |
the integrity of | 10 |
of the structure | 10 |
parp and parp | 10 |
the slippery codon | 10 |
was due to | 10 |
to generate a | 10 |
to monitor the | 10 |
daudi and sk | 10 |
there was a | 10 |
a part of | 10 |
containing mm hepes | 10 |
of the host | 10 |
majority of fs | 10 |
such that the | 10 |
reactions were performed | 10 |
even though the | 10 |
ends of the | 10 |
the homomorphs of | 10 |
we demonstrated that | 10 |
pattern of cd | 10 |
domain of the | 10 |
demonstrate that the | 10 |
the decoding center | 10 |
of rna viruses | 10 |
can act as | 10 |
position in the | 10 |
for each sample | 10 |
signals in the | 10 |
to maintain the | 10 |
be able to | 10 |
and a u | 10 |
the same as | 10 |
in the frameshift | 10 |
has also been | 10 |
in the input | 10 |
min at room | 10 |
a viral rna | 10 |
these results indicate | 10 |
proteins involved in | 10 |
alternative splicing of | 10 |
and incubated for | 10 |
was observed for | 10 |
been proposed to | 10 |
any of the | 10 |
and chop genes | 10 |
many of these | 10 |
evolution of the | 10 |
frameshifting by antisense | 10 |
new england biolabs | 10 |
been shown that | 10 |
state abundance of | 10 |
we also observed | 10 |
difference between the | 10 |
with respect to | 10 |
the availability of | 10 |
hhge per l | 10 |
sirna and silna | 10 |
we would like | 10 |
by the ribosome | 10 |
so as to | 10 |
of the u | 10 |
of the mean | 10 |
this could be | 10 |
the national center | 10 |
cells were harvested | 10 |
the alternative splicing | 10 |
into account the | 10 |
function in programmed | 10 |
was normalized to | 10 |
the viral g | 10 |
a list of | 10 |
agreement with the | 10 |
been used to | 10 |
number of sequences | 10 |
a template for | 10 |
a small molecule | 10 |
of small molecules | 10 |
predicted to be | 10 |
in combination with | 10 |
the prediction of | 10 |
the rdrp core | 10 |
the basis of | 10 |
in ml of | 10 |
of the major | 10 |
of the dpo | 10 |
amplification of the | 10 |
mechanical explanation of | 10 |
pseudoknot function in | 10 |
to verify that | 10 |
and resuspended in | 10 |
the yeast saccharomyces | 10 |
we decided to | 10 |
the first base | 10 |
is the number | 10 |
the evolution of | 10 |
a u and | 10 |
has been suggested | 10 |
the difference in | 10 |
presence of increasing | 10 |
the genetic code | 10 |
ntd of dnag | 10 |
in a similar | 10 |
there was no | 10 |
prf occurs during | 10 |
proteins encoded by | 10 |
a component of | 10 |
both types of | 10 |
terminal edge of | 10 |
limited number of | 10 |
detection of the | 10 |
were observed in | 10 |
information about the | 10 |
presence of mm | 10 |
mechanical strength of | 10 |
to examine the | 10 |
of exon skipping | 10 |
this type of | 10 |
exon of cd | 10 |
ribosome aligning with | 10 |
differences between the | 10 |
of severe acute | 10 |
level of frameshifting | 10 |
of the template | 10 |
is sensitive to | 10 |
the stimulatory rna | 10 |
rna binding by | 10 |
assay was performed | 10 |
carried out at | 10 |
the structure and | 10 |
the zero frame | 10 |
interaction between the | 10 |
binding site for | 10 |
the vicinity of | 10 |
contribute to the | 10 |
the viral rna | 10 |
and that the | 10 |
the composition of | 10 |
performed as previously | 10 |
rna and rna | 10 |
ribosomal frameshifting a | 10 |
endoplasmic reticulum stress | 10 |
to test this | 10 |
of the eukaryotic | 10 |
be found in | 10 |
gene copy number | 10 |
in some cases | 10 |
supported by the | 10 |
deletion of the | 10 |
in programmed ribosomal | 10 |
dlamp with hrm | 10 |
mm nacl and | 10 |
is not a | 10 |
of the binding | 10 |
gene expression in | 10 |
we hypothesize that | 10 |
frameshifting rna pseudoknots | 10 |
influence of the | 10 |
analysis was performed | 10 |
lna dna mix | 10 |
s rrna transcript | 10 |
the distance between | 10 |
transferred to a | 10 |
the initiation of | 10 |
in this article | 10 |
sequence in the | 10 |
consists of a | 10 |
between madp and | 10 |
which can be | 10 |
are associated with | 10 |
a range of | 10 |
it should be | 10 |
in the frame | 10 |
d exd e | 10 |
a mechanical explanation | 10 |
rna pseudoknot function | 10 |
the value of | 10 |
with a single | 9 |
to understand the | 9 |
within the pseudoknot | 9 |
of a pseudoknot | 9 |
in lysis buffer | 9 |
of this approach | 9 |
produced by the | 9 |
type and mutant | 9 |
as part of | 9 |
d and supplementary | 9 |
based on a | 9 |
the degree of | 9 |
ns b and | 9 |
the catalytic domain | 9 |
in the supplementary | 9 |
at the position | 9 |
increasing amounts of | 9 |
to note that | 9 |
obtained from the | 9 |
leading to the | 9 |
we tested the | 9 |
the genome of | 9 |
interaction between madp | 9 |
proximal to the | 9 |
were resolved by | 9 |
data show that | 9 |
cloned into the | 9 |
nucleic acid binding | 9 |
incubated for h | 9 |
g for min | 9 |
for each of | 9 |
g s have | 9 |
in t cells | 9 |
readthrough of the | 9 |
in a viral | 9 |
to fold into | 9 |
rrp and csl | 9 |
t cells were | 9 |
was mixed with | 9 |
of motif c | 9 |
whether or not | 9 |
on the ribosome | 9 |
was found in | 9 |
genes that are | 9 |
examination of the | 9 |
a and d | 9 |
flock house virus | 9 |
followed by the | 9 |
mcm side chain | 9 |
to the c | 9 |
of recoding events | 9 |
suggested that the | 9 |
the action of | 9 |
frameshift efficiency was | 9 |
a database of | 9 |
on the basis | 9 |
at the n | 9 |
ribosomal frameshifting the | 9 |
agarose gel electrophoresis | 9 |
the start of | 9 |
the base pairs | 9 |
of the codon | 9 |
cells were lysed | 9 |
r r correspondences | 9 |
these results suggest | 9 |
to estimate the | 9 |
the assumption that | 9 |
the thermodynamic stability | 9 |
of rna integrity | 9 |
on ice for | 9 |
in the n | 9 |
frameshifting at the | 9 |
crystal structures of | 9 |
evaluation of the | 9 |
dual luciferase reporter | 9 |
as it is | 9 |
were added to | 9 |
of the mutation | 9 |
plays a role | 9 |
the course of | 9 |
the ese site | 9 |
consistent with our | 9 |
and frameshift efficiency | 9 |
involved in rna | 9 |
of the samples | 9 |
in vivo studies | 9 |
role of g | 9 |
terminal region of | 9 |
used in a | 9 |
the samples were | 9 |
to test the | 9 |
highly conserved residues | 9 |
activity in the | 9 |
with h o | 9 |
and s l | 9 |
of the various | 9 |
the association of | 9 |
basis for the | 9 |
results of the | 9 |
csl exosome and | 9 |
the activation of | 9 |
resulted in the | 9 |
viral rna synthesis | 9 |
of sirt with | 9 |
function in the | 9 |
of up to | 9 |
at the surface | 9 |
of the toxin | 9 |
the mixture was | 9 |
of decoding rules | 9 |
in the previous | 9 |
with l of | 9 |
may not be | 9 |
of frameshifting in | 9 |
functional analysis of | 9 |
rna polymerase i | 9 |
levels of the | 9 |
was detected in | 9 |
length of nt | 9 |
for probe design | 9 |
the selection of | 9 |
requirement for an | 9 |
to each other | 9 |
the first nucleotide | 9 |
apoptosis in yeast | 9 |
is likely that | 9 |
results show that | 9 |
of the polymerase | 9 |
a and s | 9 |
divided by the | 9 |
sequences can be | 9 |
which has been | 9 |
to evaluate the | 9 |
this is consistent | 9 |
with frameshift efficiency | 9 |
be caused by | 9 |
fact that the | 9 |
of the l | 9 |
the kinetic model | 9 |
recognized by the | 9 |
in the xbp | 9 |
were performed in | 9 |
versions of the | 9 |
the target gene | 9 |
both in vitro | 9 |
of the lacz | 9 |
may also be | 9 |
in the assay | 9 |
to oxidative stress | 9 |
and incubated at | 9 |
be required to | 9 |
shown in the | 9 |
pestivirus ns b | 9 |
in ribosomal frameshifting | 9 |
are summarized in | 9 |
in the protein | 9 |
to reduce the | 9 |
exon skipping in | 9 |
for the presence | 9 |
to the other | 9 |
transfected with the | 9 |
the relative expression | 9 |
of the interaction | 9 |
exon of the | 9 |
ns b constructs | 9 |
for detection of | 9 |
of the in | 9 |
normalized to the | 9 |
transcription and replication | 9 |
for sg mrna | 9 |
of a specific | 9 |
not affected by | 9 |
the cytoplasm of | 9 |
incorporation of the | 9 |
the results were | 9 |
it will be | 9 |
the primers used | 9 |
ribosomal pausing at | 9 |
is crucial for | 9 |
at the same | 9 |
in the synthesis | 9 |
of the data | 9 |
development of a | 9 |
proteins that are | 9 |
hypothesis that the | 9 |
of the treble | 9 |
effects of the | 9 |
rabbit reticulocyte lysate | 9 |
to a final | 9 |
been found in | 9 |
in the expression | 9 |
of a given | 9 |
the generation of | 9 |
site loop is | 9 |
reactions were incubated | 9 |
the abundance of | 9 |
ltr promoter activity | 9 |
nt downstream of | 9 |
of mutations in | 9 |
be attributed to | 9 |
a cocktail of | 9 |
formed by the | 9 |
have demonstrated that | 9 |
to activate ifn | 9 |
of a particular | 9 |
not included in | 9 |
a highly conserved | 9 |
stabilization of the | 9 |
multiple sequence alignments | 9 |
not able to | 9 |
gel electrophoresis and | 9 |
are critical for | 9 |
fetal bovine serum | 9 |
variation in the | 9 |
stimulation of ribosomal | 9 |
by the addition | 9 |
nt of the | 9 |
are present in | 9 |
translation of an | 9 |
fold increase in | 9 |
true and false | 9 |
of the genetic | 9 |
conclude that the | 9 |
rous sarcoma virus | 9 |
ribosomal frameshift signal | 9 |
of in vitro | 9 |
ice for min | 9 |
relationship between the | 9 |
gaba a receptor | 9 |
of rna samples | 9 |
expansion of decoding | 9 |
of the control | 8 |
it may be | 8 |
been implicated in | 8 |
to have a | 8 |
and the sars | 8 |
moloney murine leukemia | 8 |
as the primary | 8 |
of the predicted | 8 |
led to the | 8 |
mobility shift assay | 8 |
the mean of | 8 |
seen in the | 8 |
and incubated with | 8 |
c and supplementary | 8 |
is induced by | 8 |
be observed in | 8 |
of a conserved | 8 |
r r matches | 8 |
interacting with the | 8 |
composed of a | 8 |
sequence of a | 8 |
in light of | 8 |
copy numbers of | 8 |
heterogeneous nuclear ribonucleoprotein | 8 |
pausing during translation | 8 |
to play a | 8 |
small interfering rnas | 8 |
this study was | 8 |
signal in the | 8 |
of stop codon | 8 |
the est mrna | 8 |
orders of magnitude | 8 |
the ebola virus | 8 |
was annealed with | 8 |
of the poly | 8 |
mechanisms by which | 8 |
terminal domain of | 8 |
and the protein | 8 |
with a nt | 8 |
formation of an | 8 |
was performed to | 8 |
of the dna | 8 |
uaa stop codon | 8 |
act as a | 8 |
primer extension activity | 8 |
mm edta and | 8 |
the utr of | 8 |
reading of the | 8 |
and quantified using | 8 |
downstream from the | 8 |
have been developed | 8 |
in l of | 8 |
all of these | 8 |
the performance of | 8 |
r t is | 8 |
the quality of | 8 |
the genome and | 8 |
addition of the | 8 |
were analyzed using | 8 |
by the ntd | 8 |
be present in | 8 |
that the rna | 8 |
an in vivo | 8 |
copies of the | 8 |
new insights into | 8 |
into the p | 8 |
by dna sequencing | 8 |
to provide a | 8 |
in rna metabolism | 8 |
a broad range | 8 |
of the read | 8 |
were infected with | 8 |
by in vitro | 8 |
carried out by | 8 |
properties of the | 8 |
to create a | 8 |
we wanted to | 8 |
determine whether the | 8 |
to examine whether | 8 |
a limited number | 8 |
of frameshift proteins | 8 |
splicing of cd | 8 |
were performed with | 8 |
in the sars | 8 |
to investigate whether | 8 |
these data suggest | 8 |
a member of | 8 |
of recombination events | 8 |
translation of the | 8 |
of the cell | 8 |
to form the | 8 |
the potential to | 8 |
propose that the | 8 |
rna polymerase and | 8 |
role for g | 8 |
has been demonstrated | 8 |
were incubated for | 8 |
the design of | 8 |
on the right | 8 |
each set of | 8 |
of the cleavage | 8 |
b and d | 8 |
cloned into a | 8 |
the correct stoichiometric | 8 |
have not been | 8 |
to make a | 8 |
sites in the | 8 |
is available at | 8 |
present in all | 8 |
is independent of | 8 |
in the reaction | 8 |
reactive oxygen species | 8 |
replication of the | 8 |
and ribosomal frameshifting | 8 |
of these viruses | 8 |
ribosomal frameshifting efficiency | 8 |
gov genome viruses | 8 |
hj secondary structure | 8 |
is dependent on | 8 |
components of the | 8 |
ibdv and ipnv | 8 |
lack of a | 8 |
terminus of the | 8 |
separated from the | 8 |
that the structure | 8 |
frameshifting efficiency and | 8 |
splicing pattern of | 8 |
m and m | 8 |
are indicative of | 8 |
mrna secondary structure | 8 |
was observed with | 8 |
were separated on | 8 |
was incubated for | 8 |
u and a | 8 |
to compare the | 8 |
in most of | 8 |
mediated mrna decay | 8 |
the s and | 8 |
a sliding window | 8 |
expression of sf | 8 |
were introduced into | 8 |
in the u | 8 |
by primer extension | 8 |
in a sequence | 8 |
the escherichia coli | 8 |
takes into account | 8 |
wild type and | 8 |
structural and functional | 8 |
the pattern of | 8 |
been identified in | 8 |
degradation by the | 8 |
expression of cd | 8 |
positions of the | 8 |
in the control | 8 |
the ns b | 8 |
of false positives | 8 |
are characterized by | 8 |
by changing the | 8 |
the protein was | 8 |
compare lanes and | 8 |
is possible to | 8 |
the dpo system | 8 |
rna pseudoknots and | 8 |
in vitro transcribed | 8 |
of the peptidyl | 8 |
analysis revealed that | 8 |
local stability of | 8 |
the notion that | 8 |
for human immunodeficiency | 8 |
end of s | 8 |
rna interactions in | 8 |
group of the | 8 |
could be due | 8 |
of this domain | 8 |
bind to the | 8 |
and the other | 8 |
the sense strand | 8 |
of pol ii | 8 |
were washed with | 8 |
cellular uptake of | 8 |
the most frequently | 8 |
reported in the | 8 |
of these two | 8 |
as in the | 8 |
the ribosome is | 8 |
distance between the | 8 |
rna by the | 8 |
and quantified by | 8 |
it is known | 8 |
the palindromic sequence | 8 |
consistent with this | 8 |
to be determined | 8 |
c virus rna | 8 |
were maintained in | 8 |
were designed to | 8 |
may be involved | 8 |
is the first | 8 |
and cloned into | 8 |
of ncl to | 8 |
to build a | 8 |
the set of | 8 |
total rna from | 8 |
subset of the | 8 |
frameshifting in decoding | 8 |
in the second | 8 |
temperature for h | 8 |
efficiency of frameshifting | 8 |
these observations suggest | 8 |
t polynucleotide kinase | 8 |
mechanism by which | 8 |
well as a | 8 |
status of the | 8 |
not present in | 8 |
regulate gene expression | 8 |
immediately downstream of | 8 |
independent of the | 8 |
ribosylation of rna | 8 |
with mg ml | 8 |
be noted that | 8 |
expression of full | 8 |
was cloned into | 8 |
d and h | 8 |
in conjunction with | 8 |
presence of an | 8 |
the infected cells | 8 |
only a small | 8 |
of h o | 8 |
resulting in the | 8 |
is required to | 8 |
case of the | 8 |
between pcaf and | 8 |
helicase activity of | 8 |
the time of | 8 |
the x xx | 8 |
with previous studies | 8 |
knockdown of sirt | 8 |
the release of | 8 |
binding of rna | 8 |
lead to the | 8 |
are used to | 8 |
in a given | 8 |
it was shown | 8 |
at the slippery | 8 |
from the a | 8 |
used as templates | 8 |
the present study | 8 |
nucleotides in the | 8 |
to the wild | 8 |
by an rna | 8 |
of the cyp | 8 |
slippery site and | 8 |
the ctd of | 8 |
this process is | 8 |
to associate with | 8 |
in a dose | 8 |
of rna polymerase | 8 |
and found that | 8 |
different from the | 8 |
mouth disease virus | 8 |
the kinetics of | 8 |
and could be | 8 |
has been previously | 8 |
generated using the | 8 |
hepatitis b virus | 8 |
the recoding site | 8 |
s have been | 8 |
that the n | 8 |
of the rt | 8 |
temperature for min | 8 |
of the above | 8 |
on the u | 8 |
were obtained by | 8 |
end labeled with | 8 |
terminal to the | 8 |
the mcm side | 8 |
trnas in the | 8 |
in a number | 8 |
functions as a | 8 |
northern blot analysis | 8 |
the rna chaperone | 8 |
the growth of | 8 |
amount of frameshifted | 8 |
and identification of | 8 |
prior to the | 8 |
may lead to | 8 |
the sum of | 8 |
in the interaction | 8 |
a reduction in | 8 |
the ntd is | 8 |
complex with a | 8 |
were generated using | 8 |
sites of the | 8 |
mechanical stability and | 8 |
the reaction mixture | 8 |
the supernatant was | 8 |
the replacement of | 8 |
conservation at synonymous | 8 |
be explained by | 8 |
of an efficient | 8 |
the authors thank | 8 |
consistent with a | 8 |
also supplementary figure | 8 |
is necessary for | 8 |
copies of a | 8 |
as a positive | 8 |
to the template | 8 |
of the archaeal | 8 |
has previously been | 8 |
the difference between | 8 |
respiratory syncytial virus | 8 |
were identified in | 8 |
half of the | 8 |
for the development | 8 |
and the final | 8 |
of the trailer | 8 |
of cell death | 8 |
to explore the | 8 |
the viral rdrp | 8 |
with the observation | 8 |
studies of the | 8 |
histone h b | 8 |
of the other | 8 |
vicinity of the | 8 |
focused on the | 8 |
of ribosomal rna | 8 |
similar to those | 8 |
to the same | 8 |
belong to the | 8 |
of frameshifting is | 8 |
it possible to | 8 |
at c in | 8 |
figure s d | 8 |
we compared the | 8 |
in cultured cells | 8 |
sequences have been | 8 |
with and without | 8 |
decoding rules enriches | 8 |
of the antisense | 8 |
the frameshifting efficiency | 8 |
its role in | 7 |
for nucleic acid | 7 |
reduction in the | 7 |
maintenance of the | 7 |
binding of ncl | 7 |
construct with the | 7 |
the rna structure | 7 |
were visualized by | 7 |
comparative analysis of | 7 |
in the reference | 7 |
this work was | 7 |
used to generate | 7 |
to allow for | 7 |
sukh superfamily neighborhoods | 7 |
of the role | 7 |
within the homomorph | 7 |
as high as | 7 |
the structurally aligned | 7 |
control of the | 7 |
with the csl | 7 |
is due to | 7 |
both in the | 7 |
cell death in | 7 |
secondary structure prediction | 7 |
function of rna | 7 |
is comparable to | 7 |
ensure synthesis of | 7 |
the illumina results | 7 |
in all cases | 7 |
in the regulation | 7 |
the luciferase activity | 7 |
mouse model of | 7 |
the tertiary structure | 7 |
as rs interaction | 7 |
a proportion of | 7 |
of pcaf in | 7 |
of dna replication | 7 |
to analyze the | 7 |
at a frameshifter | 7 |
each of these | 7 |
stem of sars | 7 |
the application of | 7 |
terminal amino acids | 7 |
of this superfamily | 7 |
the dual luciferase | 7 |
the products were | 7 |
most of them | 7 |
and nucleic acid | 7 |
of the sequences | 7 |
of amino acids | 7 |
the efficacy of | 7 |
derived from a | 7 |
lead to a | 7 |
function of time | 7 |
significant amount of | 7 |
p to p | 7 |
integrity of the | 7 |
to better understand | 7 |
set of probes | 7 |
antiviral activity of | 7 |
formed in the | 7 |
was assessed by | 7 |
are presented in | 7 |
the fidelity of | 7 |
was not observed | 7 |
with the model | 7 |
structurally aligned sequences | 7 |
the silencing activity | 7 |
the potential for | 7 |
folding of the | 7 |
well as in | 7 |
middle east respiratory | 7 |
are predicted to | 7 |
of the effects | 7 |
is found in | 7 |
reading phase but | 7 |
induction by sh | 7 |
coronaviruses ensure synthesis | 7 |
in the in | 7 |
of c for | 7 |
in the ltr | 7 |
complete loss of | 7 |
tables s and | 7 |
cell lines and | 7 |
in the latter | 7 |
is the most | 7 |
pseudoknot is sensitive | 7 |
proteins have been | 7 |
innate immune response | 7 |
from that of | 7 |
substrate was annealed | 7 |
the remaining nucleotides | 7 |
dynamic range of | 7 |
nt from the | 7 |
are stored in | 7 |
of each of | 7 |
nt in the | 7 |
of bip and | 7 |
for min in | 7 |
frame of the | 7 |
secondary structures in | 7 |
ntp entry tunnel | 7 |
prf activity of | 7 |
promoter region of | 7 |
element in the | 7 |
a single copy | 7 |
and treated with | 7 |
distribution of the | 7 |
the renilla luciferase | 7 |
veev and sinv | 7 |
s ribosomal rna | 7 |
studies on the | 7 |
nmr studies of | 7 |
c in the | 7 |
the cut site | 7 |
at the time | 7 |
the rate constant | 7 |
correlation with frameshift | 7 |
in the crystal | 7 |
that the protein | 7 |
based multiplex pcr | 7 |
of the shrna | 7 |
at a time | 7 |
those of the | 7 |
analysis of gene | 7 |
lower aptamer stem | 7 |
in the mdx | 7 |
served as a | 7 |
we examined the | 7 |
this is the | 7 |
mutant and wild | 7 |
followed by incubation | 7 |
table s and | 7 |
gibbs free energy | 7 |
in this report | 7 |
we evaluated the | 7 |
the downstream structure | 7 |
conservation of the | 7 |
of genes in | 7 |
trna arg mcm | 7 |
efficiency was calculated | 7 |
pausing at a | 7 |
was extracted from | 7 |
in the structure | 7 |
that the observed | 7 |
dependent on the | 7 |
explanation for this | 7 |
luciferase reporter assay | 7 |
the wobble position | 7 |
the incorporation of | 7 |
human and mouse | 7 |
x xxy yyz | 7 |
to increase the | 7 |
the eukaryotic ribosome | 7 |
to the cytoplasm | 7 |
and a downstream | 7 |
that interact with | 7 |
b and the | 7 |
small number of | 7 |
pseudoknot required for | 7 |
programmed cell death | 7 |
by h o | 7 |
synthesis of a | 7 |
cells were washed | 7 |
in an elp | 7 |
appears that the | 7 |
for expression of | 7 |
by the manufacturer | 7 |
of sirt in | 7 |
defined as the | 7 |
number of non | 7 |
inside the pseudoknot | 7 |
mrna destabilizing elements | 7 |
did not affect | 7 |
correct stoichiometric ratios | 7 |
of which are | 7 |
to reading phase | 7 |
a golden mean | 7 |
the extent of | 7 |
identified as a | 7 |
the copy number | 7 |
only a few | 7 |
achieving a golden | 7 |
bovine viral diarrhea | 7 |
ribosomal frameshifting is | 7 |
the strength of | 7 |
little correlation with | 7 |
the spacer region | 7 |
of the ctd | 7 |
frameshifter rna pseudoknot | 7 |
utr of the | 7 |
bound to the | 7 |
specific recognition of | 7 |
phase but shows | 7 |
characterized by a | 7 |
ribosomal frameshifting on | 7 |
to explain the | 7 |
mrna and the | 7 |
as compared to | 7 |
batch sequence retrieval | 7 |
different levels of | 7 |
the minimal ibv | 7 |
the promotion of | 7 |
the gel was | 7 |
the exosome containing | 7 |
the translation of | 7 |
lower than that | 7 |
c bl j | 7 |
level of the | 7 |
of dnag is | 7 |
that the majority | 7 |
representation of the | 7 |
to the rna | 7 |
absence of a | 7 |
samples were incubated | 7 |
using a typhoon | 7 |
affinity to the | 7 |
have been proposed | 7 |
is an important | 7 |
by which coronaviruses | 7 |
at a frequency | 7 |
to the virus | 7 |
been reported that | 7 |
understanding of the | 7 |
between the slippery | 7 |
appear to be | 7 |
are found in | 7 |
we anticipate that | 7 |
highly conserved in | 7 |
choi et al | 7 |
is the same | 7 |
love et al | 7 |
were generated by | 7 |
in a manner | 7 |
the ebov trailer | 7 |
under the following | 7 |
and s rrna | 7 |
from genomic dna | 7 |
do not have | 7 |
as a consequence | 7 |
its interaction with | 7 |
cloned into pet | 7 |
sukh domain proteins | 7 |
transcription and translation | 7 |
in the terminal | 7 |
wn and denv | 7 |
element of the | 7 |
rules enriches gene | 7 |
insight into the | 7 |
belongs to the | 7 |
to the target | 7 |
the g structure | 7 |
fraction of the | 7 |
there are no | 7 |
characterization of ribosomal | 7 |
between in vitro | 7 |
sh r t | 7 |
of ebola virus | 7 |
motifs a and | 7 |
and inhibition of | 7 |
of the firefly | 7 |
was measured using | 7 |
expression of a | 7 |
the reference sequence | 7 |
final volume of | 7 |
of the stimulatory | 7 |
at least two | 7 |
frameshifting ribosomal pausing | 7 |
except for the | 7 |
homomorph of motif | 7 |
in all three | 7 |
viral diarrhea virus | 7 |
to be an | 7 |
were separated by | 7 |
the rdrp palm | 7 |
luciferase activity of | 7 |
little or no | 7 |
the vast majority | 7 |
of the complex | 7 |
of this article | 7 |
different types of | 7 |
the northern blot | 7 |
was achieved by | 7 |
to enter the | 7 |
the frameshift products | 7 |
have already been | 7 |
of motif a | 7 |
design of a | 7 |
see materials and | 7 |
the input set | 7 |
sensitive to reading | 7 |
driven by the | 7 |
for viral replication | 7 |
upstream from the | 7 |
ge healthcare life | 7 |
corresponds to the | 7 |
east respiratory syndrome | 7 |
as a potential | 7 |
using a single | 7 |
determined by a | 7 |
transcription of the | 7 |
it does not | 7 |
figure s and | 7 |
to in figure | 7 |
to bind to | 7 |
of which is | 7 |
mrna transcription in | 7 |
because they are | 7 |
rna was isolated | 7 |
the rous sarcoma | 7 |
the structures of | 7 |
can be observed | 7 |
of the sh | 7 |
but not in | 7 |
of nsp and | 7 |
recent advances in | 7 |
found in a | 7 |
arg mcm ucu | 7 |
overlaps with the | 7 |
the probability of | 7 |
a family of | 7 |
efficient coronavirus ribosomal | 7 |
determination of the | 7 |
can be a | 7 |
respect to the | 7 |
figures s a | 7 |
specific binding of | 7 |
uniformly labeled samples | 7 |
separated by a | 7 |
figures a and | 7 |
vast majority of | 7 |
in viral rna | 7 |
aligned sequences that | 7 |
were performed at | 7 |
have focused on | 7 |
for translational frameshifting | 7 |
esterified methyl group | 7 |
the expression levels | 7 |
pol ii transcription | 7 |
production of the | 7 |
the s l | 7 |
the ribosome and | 7 |
a frameshifter rna | 7 |
the characterization of | 7 |
to be more | 7 |
h after transfection | 7 |
sequences based on | 7 |
c of the | 7 |
parp catalytic domain | 7 |
by antisense oligonucleotides | 7 |
analogous to the | 7 |
healthcare life sciences | 7 |
in a dna | 7 |
relative to wild | 7 |
rna pseudoknot is | 7 |
specific conjugate d | 7 |
nuclear magnetic resonance | 7 |
nucleotide of the | 7 |
translocational ribosome aligning | 7 |
by using the | 7 |
of the sense | 7 |
the ebov e | 7 |
a minimum of | 7 |
shown in table | 7 |
nef coding region | 7 |
of the cellular | 7 |
as an rna | 7 |
to wild type | 7 |
to the stop | 7 |
uag stop codon | 7 |
structure in the | 7 |
with rna and | 7 |
the requirement of | 7 |
the host cell | 7 |
reported to be | 7 |
by western blot | 7 |
in spite of | 7 |
which correspond to | 7 |
increased expression of | 7 |
residues at the | 7 |
ntd and the | 7 |
used to determine | 7 |
a and supplementary | 7 |
the normalized chi | 7 |
the structural basis | 7 |
only in the | 7 |
the most efficient | 7 |
p and p | 7 |
of the ltr | 7 |
as that of | 7 |
of programmed ribosomal | 7 |
is a major | 7 |
shows little correlation | 7 |
system for the | 7 |
in support of | 7 |
was unable to | 7 |
the primer extension | 7 |
upf d cells | 7 |
was designed to | 7 |
the target cells | 7 |
this is an | 7 |
a correlation between | 7 |
an efficient coronavirus | 7 |
that the presence | 7 |
sequencing of the | 7 |
crucial for the | 7 |
the first time | 7 |
the pestivirus ns | 7 |
important for the | 7 |
no significant differences | 7 |
with some modifications | 7 |
the sample set | 7 |
to produce a | 7 |
the dynamic range | 7 |
was also observed | 7 |
serves as a | 7 |
possible that the | 7 |
to result in | 7 |
characterization of an | 7 |
b and supplementary | 7 |
a fusion protein | 7 |
a critical role | 7 |
frameshift efficiency and | 7 |
was isolated from | 7 |
to validate the | 7 |
are linked to | 7 |
chaperone activity of | 7 |
available at http | 7 |
of the natural | 7 |
which coronaviruses ensure | 7 |
of the est | 7 |
known to be | 7 |
and has been | 7 |
rna binding activity | 7 |
value of the | 7 |
sf asf in | 7 |
activity in vitro | 7 |
attributed to the | 7 |
of a dna | 7 |
the potential of | 7 |
enriches gene expression | 7 |
is known that | 7 |
of the antiviral | 7 |
probing analysis of | 7 |
of the mature | 7 |
quadruplex nucleic acids | 7 |
broad range of | 7 |
in the stem | 7 |
number of the | 7 |
of viral genome | 7 |
is separated from | 7 |
for the first | 7 |
as a control | 7 |
in this context | 7 |
structure has been | 7 |
that it is | 7 |
of the reporter | 7 |
of the duplex | 7 |
with the rdrp | 7 |
we did not | 7 |
data structures and | 7 |
of total rna | 7 |
the rin system | 7 |
results demonstrate that | 7 |
significant decrease in | 7 |
does not require | 7 |
mechanical unfolding of | 7 |
observed for the | 7 |
but shows little | 7 |
the pip a | 7 |
change in the | 7 |
a mechanism for | 7 |
that has been | 7 |
an elp mutant | 7 |
compared to a | 7 |
possibility that the | 7 |
of archaeal dnag | 7 |
is determined by | 7 |
of both the | 7 |
that of a | 7 |
the frameshift signal | 7 |
these results are | 7 |
located within the | 7 |
the rna samples | 7 |
illustrated in figure | 7 |
computational binding site | 7 |
sought to determine | 7 |
for the prediction | 7 |
systems such as | 7 |
represented by r | 7 |
or a p | 7 |
the esterified methyl | 7 |
the list of | 7 |
the query sequence | 7 |
the left of | 7 |
probabilistic data structures | 7 |
is regulated by | 7 |
of these proteins | 7 |
relative copy number | 7 |
site in the | 7 |
by a single | 7 |
lower than the | 7 |
increase in fs | 7 |
with high affinity | 7 |
we hypothesized that | 7 |
of the four | 7 |
genes and genomes | 7 |
of a unique | 7 |
the assembly of | 7 |
the folding of | 7 |
stoichiometric ratios of | 7 |
sequences at the | 7 |
were transformed into | 7 |
typified by the | 7 |
no effect on | 7 |
to determine if | 7 |
vp in the | 7 |
b and b | 7 |
the mechanisms of | 7 |
the nucleocapsid protein | 7 |
by the rna | 7 |
used to assess | 7 |
ratios of viral | 7 |
occurs in the | 7 |
nucleic acids in | 7 |
a potential target | 7 |
number of methionines | 7 |
rtsl and ld | 7 |
single nucleotide polymorphisms | 6 |
p ssrna cy | 6 |
critical role in | 6 |
the following conditions | 6 |
thought to be | 6 |
the transfected cells | 6 |
pseudoknots promote efficient | 6 |
assessment of the | 6 |
denaturing polyacrylamide gel | 6 |
a significant amount | 6 |
of a large | 6 |
to address these | 6 |
to investigate this | 6 |
for g s | 6 |
center of the | 6 |
needs to be | 6 |
u a slippery | 6 |
of rna interference | 6 |
under the control | 6 |
bicistronic reporter system | 6 |
x xxz zzn | 6 |
human breast cancer | 6 |
copy number variation | 6 |
is used as | 6 |
in the initiation | 6 |
the results showed | 6 |
the ncm group | 6 |
the cell nucleus | 6 |
the untranslated region | 6 |
the wt ltr | 6 |
lack of mcm | 6 |
of frameshifted ribosomes | 6 |
trna glu mcm | 6 |
that positional clustering | 6 |
required for viral | 6 |
nar gkq sha | 6 |
of the hepatitis | 6 |
using a combination | 6 |
rna in the | 6 |
stalled at the | 6 |
strength of messenger | 6 |
be interesting to | 6 |
of dna g | 6 |
roche applied science | 6 |
step in the | 6 |
the mcm group | 6 |
to the cleavage | 6 |
belonging to the | 6 |
the same genome | 6 |
mcf cells were | 6 |
prokaryotes and eukaryotes | 6 |
in a set | 6 |
coverage of the | 6 |
for in vitro | 6 |
mechanisms of action | 6 |
tertiary structure of | 6 |
the university of | 6 |
the mrna entrance | 6 |
of the individual | 6 |
interactions of the | 6 |
released from the | 6 |
pluc cells were | 6 |
and western blot | 6 |
that were used | 6 |
we generated a | 6 |
for the binding | 6 |
motifs in the | 6 |
sensitivity and specificity | 6 |
in the e | 6 |
subjected to a | 6 |
target for antiviral | 6 |
the contribution of | 6 |
to be highly | 6 |
functions of the | 6 |
reporter system for | 6 |
was consistent with | 6 |
mode of action | 6 |
the most conserved | 6 |
and the ribosome | 6 |
the same time | 6 |
of the anticodon | 6 |
the construction of | 6 |
transfected ft cells | 6 |
overexpression of the | 6 |
containing mm nacl | 6 |
the emergence of | 6 |
we showed that | 6 |
in living cells | 6 |
there are two | 6 |
was subjected to | 6 |
as a novel | 6 |
three independent experiments | 6 |
bloom filter for | 6 |
nucleotide sequence of | 6 |
interaction in the | 6 |
the frameshift product | 6 |
of a new | 6 |
ri rna synthesis | 6 |
t m was | 6 |
to map the | 6 |
values of the | 6 |
a new segment | 6 |
were calculated as | 6 |
supported by a | 6 |
of a slippery | 6 |
amount of protein | 6 |
length in the | 6 |
of the de | 6 |
ribosomal frameshifting and | 6 |
as measured by | 6 |
were employed to | 6 |
specific amplification products | 6 |
in the luciferase | 6 |
of the conjugates | 6 |
this is in | 6 |
prepared as described | 6 |
structures can act | 6 |
number of nucleotides | 6 |
we performed a | 6 |
structures in an | 6 |
in the range | 6 |
classified as reliable | 6 |
is identical to | 6 |
and firefly luciferase | 6 |
role of rna | 6 |
the rt codon | 6 |
a or u | 6 |
ribosomal rna in | 6 |
mapped to the | 6 |
electrophoretic mobility shift | 6 |
the influenza virus | 6 |
large ribosomal subunit | 6 |
h d class | 6 |
domains of life | 6 |
may be due | 6 |
of the is | 6 |
to use a | 6 |
and the pseudoknot | 6 |
a frequency of | 6 |
escherichia coli dnax | 6 |
gene of interest | 6 |
locked nucleic acids | 6 |
the most common | 6 |
a partially double | 6 |
mixture was incubated | 6 |
been reported in | 6 |
not only the | 6 |
higher level of | 6 |
of a gene | 6 |
an example of | 6 |
assays were carried | 6 |
according to manufacturer | 6 |
on the left | 6 |
the primer pairs | 6 |
beet western yellows | 6 |
we determined the | 6 |
the fhv genome | 6 |
telomeric g s | 6 |
in the model | 6 |
sk snrnp complex | 6 |
with an anti | 6 |
ribosomal frameshift in | 6 |
of the type | 6 |
renilla and firefly | 6 |
a positive control | 6 |
result of the | 6 |
mm tris ph | 6 |
to induce ribosomal | 6 |
neuronal cell lines | 6 |
to a set | 6 |
the relative abundance | 6 |
and h pi | 6 |
the nuclease domain | 6 |
of the experimental | 6 |
for binding of | 6 |
no correlation between | 6 |
of a small | 6 |
corresponding to a | 6 |
is illustrated in | 6 |
b and sh | 6 |
to mg ml | 6 |
generation sequencing data | 6 |
group of proteins | 6 |
how mrna pseudoknots | 6 |
pairing of the | 6 |
h o and | 6 |
is linked to | 6 |
existence of a | 6 |
pol ii occupancy | 6 |
fold lower than | 6 |
major histocompatibility complex | 6 |
of the lna | 6 |
studying recoding signals | 6 |
pcr amplification of | 6 |
were normalized to | 6 |
a group of | 6 |
single nucleotide polymorphism | 6 |
mm h o | 6 |
protein data bank | 6 |
and used for | 6 |
small molecules targeting | 6 |
in the target | 6 |
containing mm tris | 6 |
of the homomorphs | 6 |
of the aa | 6 |
the change in | 6 |
pseudoknot enhance mechanical | 6 |
by r t | 6 |
frameshift efficiency is | 6 |
potential to form | 6 |
of the observed | 6 |
g s and | 6 |
was analyzed by | 6 |
stability and frameshift | 6 |
high level of | 6 |
treatment with h | 6 |
there are several | 6 |
shift site and | 6 |
a ratio of | 6 |
bovine serum albumin | 6 |
is the major | 6 |
of motif f | 6 |
the hj secondary | 6 |
version of this | 6 |
we thank dr | 6 |
cytoplasmic polyhedrosis virus | 6 |
replaced by a | 6 |
did not change | 6 |
helix of the | 6 |
to distinguish between | 6 |
and thus the | 6 |