quadgram

This is a table of type quadgram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

quadgram frequency
severe acute respiratory syndrome444
acute respiratory syndrome coronavirus229
cd and cd t218
in the absence of210
and cd t cells192
has been shown to190
chronic obstructive pulmonary disease163
middle east respiratory syndrome158
cd t cells in150
have been shown to139
of cd t cells136
in the context of130
acute respiratory distress syndrome129
cd t cell responses125
for the treatment of117
in the presence of115
on the other hand113
east respiratory syndrome coronavirus104
specific cd t cells103
been shown to be102
the absence of any101
of severe acute respiratory101
as well as the99
was conducted in the98
that the research was98
the research was conducted98
research was conducted in98
commercial or financial relationships97
that could be construed97
any commercial or financial97
as a potential conflict97
absence of any commercial97
of any commercial or97
potential conflict of interest97
conducted in the absence97
or financial relationships that97
be construed as a97
an important role in97
relationships that could be97
could be construed as97
a potential conflict of97
financial relationships that could97
construed as a potential97
in patients with covid94
memory cd t cells93
in the case of91
the innate immune response90
declare that the research89
authors declare that the89
in the pathogenesis of89
of the immune system87
cd t cell epitopes84
or reproduction is permitted81
comply with these terms81
s in supplementary material81
which does not comply81
distribution or reproduction is81
not comply with these81
is permitted which does81
reproduction is permitted which81
does not comply with81
permitted which does not81
in accordance with accepted80
with accepted academic practice80
accordance with accepted academic80
the authors declare that80
frontiers in immunology www79
t cells in the79
in a mouse model79
this journal is cited77
and that the original77
publication in this journal77
in this journal is77
the original publication in77
that the original publication77
credited and that the77
are credited and that77
it has been shown77
original publication in this77
in vitro and in76
and cd t cell75
and the copyright owner75
provided the original author75
or reproduction in other74
in other forums is74
distribution or reproduction in74
innate and adaptive immune74
of the creative commons74
terms of the creative74
the creative commons attribution74
under the terms of74
creative commons attribution license74
other forums is permitted74
distributed under the terms74
the terms of the74
article distributed under the74
reproduction in other forums74
porcine reproductive and respiratory73
respiratory syncytial virus infection72
reproductive and respiratory syndrome72
on the surface of71
access article distributed under71
cd t cells and71
of type i interferon71
this is an open71
in patients with severe69
in the treatment of68
a mouse model of68
vitro and in vivo68
for the development of67
has been shown that67
the innate immune system64
in cd t cells63
play an important role62
and respiratory syndrome virus62
peripheral blood mononuclear cells60
of influenza a virus59
with severe acute respiratory58
studies have shown that53
as well as in53
figure s in supplementary53
of the immune response52
cd t cells are52
cd t cells were52
of cd t cell52
in the lungs of52
also been shown to51
in addition to the50
of type i ifn50
it is possible that49
in the respiratory tract49
of the innate immune49
porcine epidemic diarrhea virus49
as a result of49
in the united states49
one of the most48
the central nervous system48
in the development of48
the immune response to48
in the regulation of47
has also been shown47
specific cd t cell47
these data suggest that47
in chronic obstructive pulmonary46
the cd t cell46
was found to be46
h n influenza virus45
patients with severe covid44
lag and cd b44
innate and adaptive immunity44
cd t cell response44
the adaptive immune response44
respiratory syndrome coronavirus infection43
in the peripheral blood43
t cells in covid43
and adaptive immune responses43
a critical role in43
play a role in43
systematic review and meta43
a systematic review and42
c a and c42
cd t cells from41
of t cells in41
influenza a virus infection41
it is important to41
it was shown that41
at the time of41
inflammatory cytokines and chemokines40
of chronic obstructive pulmonary40
a wide range of40
patients with severe acute40
in a murine model40
all authors contributed to40
of middle east respiratory40
the expression of the39
were found to be39
been found to be39
the activation of the39
a key role in38
a and c a38
has been reported to38
type i ifn production38
of cd and cd38
is one of the38
authors contributed to the38
of patients infected with37
the supplementary material for37
the role of the37
for this article can37
can be found online37
the severe acute respiratory37
supplementary material for this37
type i interferon signaling37
material for this article37
article can be found37
be found online at37
mhc class i molecules37
this article can be37
type i interferon production36
approved the submitted version36
a murine model of36
and approved the submitted36
contributed to the article35
to the article and35
on cd t cells35
of the nlrp inflammasome35
the article and approved35
article and approved the35
of lag and cd34
as shown in figure34
patients with coronavirus disease34
the expression levels of34
both cd and cd34
type i and iii33
at the same time33
are involved in the33
innate immune response to32
clinical features of patients32
producing cd t cells32
of cd c microglia32
plays an important role32
in severe acute respiratory31
with respiratory syncytial virus31
major histocompatibility complex class31
the development of a31
cd t cells is31
the production of ifn30
a large number of30
reviewed and approved by30
of patients with covid30
it has been demonstrated30
was shown to be30
with novel coronavirus in30
cd t cell epitope30
t cell responses in30
the results showed that30
infected with novel coronavirus29
of respiratory syncytial virus29
patients infected with novel29
by cd t cells29
compared to healthy controls29
of the t cell29
novel coronavirus in wuhan29
macrophage migration inhibitory factor29
it has been reported29
critically ill patients with29
cd t cells to29
features of patients infected29
has been found to29
and the development of29
cells in patients with28
the innate and adaptive28
important role in the28
cd t cells that28
has been associated with28
a major role in28
a significant increase in28
t cell responses to28
with acute respiratory distress28
that cd t cells28
has been reported that27
cells in the lung27
be involved in the27
influenza a h n27
expression of lag and27
have been reported to27
as compared to the27
in the induction of27
at the site of27
to be involved in27
it has also been26
has been demonstrated that26
regulatory t cells in26
type i and type26
the influenza a virus26
is associated with a26
in a model of26
in the present study26
to the development of26
t cell epitope discovery26
table s in supplementary26
to severe acute respiratory26
cd t cell populations26
is involved in the25
was approved by the25
macrophages and dendritic cells25
of natural killer cells25
a member of the25
play a critical role25
the treatment of covid25
both innate and adaptive25
of the airway epithelium25
the lower respiratory tract25
the host immune response25
in accordance with the25
cells were transfected with25
the world health organization25
may be involved in25
we found that the25
is essential for the25
to the activation of25
to the induction of25
with chronic obstructive pulmonary25
and wrote the manuscript25
influenza a virus ns25
safety and immunogenicity of25
the first line of25
of the s protein24
it should be noted24
type i interferon response24
first line of defense24
the type i interferon24
cd t cells during24
may contribute to the24
a role in the24
cd t cell subsets24
is thought to be24
memory cd t cell24
histocompatibility complex class i24
the severity of the24
in health and disease24
are included in the23
induction of type i23
type i ifn signaling23
of the adaptive immune23
of mhc class i23
it has been suggested23
in a variety of23
during influenza virus infection23
of the complement system23
study are included in23
at least in part23
in balb c mice23
have the potential to23
in airway epithelial cells23
cells as well as23
to influenza a virus23
to cd t cells23
been reported to be23
in response to ifn23
human cd t cells23
specific memory cd t23
has been suggested that23
the immune response against23
in contrast to the23
an increase in the23
have been associated with22
are more susceptible to22
a novel coronavirus from22
in the immune response22
in a number of22
human immunodeficiency virus type22
t and b cell22
by the presence of22
of nk cells in22
in the activation of22
in cells infected with22
h at room temperature22
t cell response to22
should be noted that22
to the production of22
lncisg and lncbst bispr22
the site of infection22
induces the expression of22
expression in cd t22
to the site of22
was used as a22
cd cd t cells22
it has been proposed22
innate immune responses to22
for h at room21
to be associated with21
in the control of21
on cd and cd21
in patients with chronic21
as one of the21
this work was supported21
cells and cd t21
vivo and in vitro21
n and h n21
response in patients with21
analysis was performed using21
class i and ii21
tumor necrosis factor alpha21
associated with acute respiratory21
type i interferon responses21
in the immune system21
it was found that21
production of type i21
in the production of21
chimeric antigen receptor t21
an essential role in21
in the number of21
in vivo and in21
h n and h21
a central role in21
a reduction in the21
of the influenza virus20
work was supported by20
for disease control and20
cytokines and chemokines in20
on the basis of20
it is likely that20
been shown that the20
patients compared to healthy20
has been proposed that20
disease control and prevention20
in the host macrophages20
and the production of20
the production of il20
the early phase of20
activation of the nlrp20
has been demonstrated to20
in a patient with20
the upper respiratory tract20
the surface of the20
these results suggest that20
cytokines such as il20
increase the risk of20
in patients with coronavirus20
have been found to20
of regulatory t cells20
to the plasma membrane20
for the induction of20
over the course of20
of neutrophil extracellular traps20
activated cd t cells20
were shown to be20
of type i interferons20
the presence of ibalt20
also been found to20
the peripheral blood of20
of porcine reproductive and20
of type i and20
the type i ifn19
the article supplementary material19
the spike protein of19
a wide variety of19
be due to the19
to respiratory syncytial virus19
by the innate immune19
signal transducer and activator19
influenza virus infection in19
plays a key role19
the adaptive immune system19
included in the article19
patients infected with sars19
a better understanding of19
for the first time19
in the generation of19
of innate immune cells19
our understanding of the19
transducer and activator of19
the host immune system19
human bronchial epithelial cells19
human airway epithelial cells19
patients with novel coronavirus19
the acute phase of19
a pivotal role in19
cells in the lungs19
infection is associated with19
herpes simplex virus type19
in the central nervous19
in the article supplementary19
the mechanisms by which18
used in this study18
patients with chronic obstructive18
natural killer cells in18
a negative regulator of18
the presence of a18
t cells in patients18
new insights into the18
to the pathogenesis of18
a broad spectrum of18
to the lack of18
of the cytokine storm18
have also been shown18
induce the expression of18
of inflammatory cytokines and18
by severe acute respiratory18
during the course of18
been shown to have18
are listed in table18
type i ifn response18
have shown that the18
results showed that the18
a retrospective cohort study18
the development of the18
the formation of the18
type i interferon and18
has been described in18
a h n virus18
and activator of transcription18
identification and characterization of18
high levels of il18
important to note that18
of hepatitis c virus18
studies are needed to18
may be due to18
would like to thank18
of tumor necrosis factor18
on the one hand18
the total number of18
immune response in patients17
immune responses in the17
express high levels of17
innate immune response in17
plays a role in17
respiratory syncytial virus in17
it is clear that17
stimulator of interferon genes17
and tumor necrosis factor17
nk cells in the17
of type i ifns17
of hospitalized patients with17
of the central nervous17
is dependent on the17
been shown to induce17
virus infection in mice17
pandemic h n influenza17
in the expression of17
a virus ns protein17
is based on the17
hepatitis c virus infection17
as a consequence of17
of porcine epidemic diarrhea17
can be found in17
of the cd t17
incubated for h at17
spike protein of sars17
was added to the17
the immune system and17
in patients infected with17
of the inflammatory response17
has also been reported17
of cytokines and chemokines17
in the lungs and17
be one of the17
was observed in the17
is important to note17
t cells and cd17
this study are included17
is possible that the17
these data indicate that17
plays a critical role17
at a dose of17
we would like to17
the production of type17
i interferon production by17
of patients with severe17
from patients with pneumonia17
these results indicate that17
is mediated by the17
patients with type diabetes16
for the presence of16
the role of cd16
and incubated for h16
with type diabetes mellitus16
cd regulatory t cells16
consider cytokine storm syndromes16
and data not shown16
as part of the16
of high levels of16
t cell epitopes and16
syncytial virus infection in16
the inactive x chromosome16
effects of vitamin d16
care and use committee16
cd t cell effector16
key role in the16
the acute respiratory distress16
cd t cells with16
of innate and adaptive16
coronavirus from patients with16
in the current study16
approved it for publication16
mitochondrial antiviral signaling protein16
the protective role of16
efficacy and safety of16
and is associated with16
both in vitro and16
was supported by the16
were reviewed and approved16
for the generation of16
the expression of several16
i and type iii16
also been observed in16
in the setting of16
in cd t cell16
in mice infected with16
as well as a16
of proinflammatory cytokines and16
the intensive care unit16
cytotoxic cd t cells16
the majority of the16
cytokine storm syndromes and16
patients with pneumonia in16
storm syndromes and immunosuppression16
severity of the disease16
the function of the16
due to the lack16
better understanding of the16
at the end of16
a vital role in16
novel coronavirus from patients16
is associated with the16
and chronic obstructive pulmonary16
studies involving human participants16
the studies involving human16
highly pathogenic avian influenza16
it was demonstrated that16
i and iii ifns16
activation of innate immune16
lag cd b t16
challenged ttp ko mice16
animal care and use16
for this study are16
role of cd t16
with pneumonia in china16
immune response in the16
was associated with a16
regulation of type i15
can also lead to15
that the presence of15
absence or presence of15
and then infected with15
the absence or presence15
regulatory t cells and15
human respiratory syncytial virus15
inducible nitric oxide synthase15
in acute respiratory distress15
for cd t cells15
in mouse models of15
a systematic review of15
for mhc class i15
of immune response in15
human participants were reviewed15
was performed using the15
involving human participants were15
in systemic lupus erythematosus15
studies have demonstrated that15
in hospitalized patients with15
in the bone marrow15
were approved by the15
also found to be15
of t cells and15
it remains to be15
in the absence or15
the ability of the15
and respiratory syncytial virus15
with the use of15
pathological findings of covid15
one of the main15
it is difficult to15
in patients with type15
to the presence of15
and activation of the15
play a key role15
can be induced by15
to contribute to the15
and the expression of15
inflammatory cytokines such as15
regulatory cd t cells15
of duck primary cells15
the stability of the15
of the transcription factors15
in the airways of15
cd t cells can15
in the innate immune15
for the activation of15
the t cell response15
has yet to be15
remains to be determined15
in line with the15
during the acute phase15
of herpes simplex virus15
response to influenza virus15
specific t cell responses15
t cells in a15
for min at rt15
in t dm patients15
regulate the expression of15
has been linked to15
with the development of15
is associated with increased15
participants were reviewed and15
the composition of the15
with the aid of15
of the type i14
of a novel coronavirus14
study was reviewed and14
was reviewed and approved14
regulates the expression of14
cd t cells also14
blocked by a clinically14
types of duck primary14
dysregulated type i interferon14
against influenza virus infection14
by a clinically proven14
a clinically proven protease14
has been observed in14
the early stage of14
of memory cd t14
written informed consent to14
there is evidence that14
in the serum of14
in the lung and14
to an increase in14
similar to that of14
hospitalized patients with covid14
in the recognition of14
cells in response to14
activation in response to14
h n influenza a14
cause lethal pneumonia in14
and immunogenicity of a14
the s protein of14
t and b cells14
the presence of the14
when compared to the14
in the course of14
depends on ace and14
is blocked by a14
foxp regulatory t cells14
and is blocked by14
has been proposed to14
entry depends on ace14
safety and efficacy of14
a pathogenic role for14
the treatment of severe14
in support of this14
patients with multiple sclerosis14
mhc class i and14
to the severity of14
treatment of severe covid14
had a score of14
role of t cells14
clinically proven protease inhibitor14
ace and tmprss and14
cd t cell immunity14
of the novel coronavirus14
on the role of14
cd t cells was14
with an increase in14
characteristics of cases of14
i interferon and inflammatory14
have been implicated in14
cd b t cells14
patients with rheumatoid arthritis14
of interferon regulatory factor14
play important roles in14
in the pathophysiology of14
national health commission of14
mechanism of action of14
cd t cells following14
inhibits type i interferon14
in the lower respiratory14
can lead to the14
cell entry depends on14
activates the nlrp inflammasome14
to the corresponding author14
datasets generated for this14
cells were infected with14
response to viral infection14
tmprss and is blocked14
mice immunized with pref14
responses cause lethal pneumonia14
play a major role14
has the potential to14
t cell response in14
the potential role of14
lethal pneumonia in sars14
and its role in14
generated for this study14
and tmprss and is14
on ace and tmprss14
an important role for14
isolation and characterization of14
units ml of ifn14
a crucial role in13
been shown to inhibit13
neutrophil extracellular traps in13
the case of the13
contribution to the work13
compared to the control13
ethics committee of the13
west nile virus infection13
and approved it for13
for the detection of13
influenza a virus replication13
cells have been shown13
the differentially expressed genes13
exhaustion of t cells13
been shown to activate13
immune response to influenza13
producing lag cd b13
also contribute to the13
heavy and light chain13
the production of pro13
interferon and inflammatory monocyte13
are essential for the13
and the immune system13
is in line with13
type i interferon induction13
used to evaluate the13
the prophylactic activity of13
antiviral innate immune response13
of differentially expressed genes13
which has been shown13
leads to the activation13
the human immune system13
is consistent with the13
through the induction of13
intellectual contribution to the13
is responsible for the13
hospitalized patients with novel13
involved in the regulation13
compared to healthy individuals13
the best of our13
immune response against the13
the humoral immune response13
respiratory syndrome coronavirus and13
identification of a novel13
on the development of13
patients were treated with13
a high level of13
of the influenza a13
center for disease control13
respiratory distress syndrome and13
be used as a13
severe cases of covid13
role for cd t13
cd t cells as13
in the form of13
of reactive oxygen species13
antibody responses to sars13
it was reported that13
five types of duck13
dysregulation of immune response13
animal study was reviewed13
and clinical characteristics of13
to a reduction in13
data suggest that the13
t cell effector functions13
cd t cell exhaustion13
has been reported in13
for the management of13
to better understand the13
role in the development13
expression of inhibitory receptors13
the results show that13
the innate immune responses13
to the best of13
mait cell frequencies in13
the immune response in13
s protein of sars13
these findings suggest that13
be explained by the13
the animal study was13
best of our knowledge13
macrophage responses cause lethal13
cd t cell stimulatory13
innate immunity in the13
a positive regulator of13
it is possible to13
statistical analysis was performed13
immune cells such as13
on the use of13
with the presence of13
in influenza virus infection13
the crude extract containing13
the nature of the13
a broad range of13
the induction of type13
min at room temperature12
could be used to12
clinical characteristics of hospitalized12
with a new coronavirus12
in the human population12
one of the key12
the severity of covid12
participate in this study12
cd t cell population12
the use of a12
authors listed have made12
of nk cells and12
the regulation of il12
may play a role12
and functional exhaustion of12
of the transcription factor12
it is also possible12
a final volume of12
are more likely to12
in a cohort of12
with the expression of12
of the inactive x12
chronic inflammatory lung diseases12
the nlrp inflammasome in12
upper and lower respiratory12
the respiratory tract of12
in patients with sars12
and the number of12
and function of the12
be associated with the12
increased levels of il12
have been found in12
the t cell receptor12
of the spike protein12
on the surfaces of12
may be responsible for12
but not in the12
are responsible for the12
in the lung following12
t cell monocyte cocultures12
cd c microglia in12
of novel coronavirus pneumonia12
in experimental autoimmune encephalomyelitis12
by mhc class i12
review of the literature12
no significant differences in12
responses in patients with12
all authors listed have12
at later time points12
of effector t cells12
the course of infection12
cells and nk cells12
consent to participate in12
these observations suggest that12
and the activation of12
frontiers in immunology microbial12
a single dose of12
an increased risk of12
the expression level of12
and it has been12
by the fact that12
a result of the12
in the tumor microenvironment12
in a phase i12
in immunology microbial immunology12
in the spinal cord12
it is known that12
an animal model of12
our results showed that12
of innate immune responses12
cells of the immune12
restricted cd t cell12
characteristics of hospitalized patients12
cells in the absence12
is known about the12
role in the pathogenesis12
produce high levels of12
innate immune responses in12
of the role of12
may be associated with12
specific cd and cd12
cd t cells have12
on t cells in12
the activity of the12
type i interferons in12
respiratory syncytial virus disease12
associated with disease severity12
was associated with increased12
listed have made a12
studies are required to12
at the peak of12
has also been observed12
a key role for12
an innate immune response12
the expression of genes12
for the recognition of12
also been associated with12
of the respiratory tract12
h n influenza viruses12
and the cells were12
informed consent to participate12
of major histocompatibility complex12
cytokine storm in covid12
play a central role12
to play an important12
as well as for12
the immune response of12
through the use of12
of the university of12
and intellectual contribution to12
crude extract containing coe12
the results of the12
in patients with acute12
the presence of anti12
in critically ill patients12
dendritic cells in the12
have also been found12
characteristics of coronavirus disease12
shown in figure a12
were detected in the12
during respiratory syncytial virus12
has also been found12
stimulated cd t cells12
to participate in this12
in humans and mice12
the cd c microglia12
production of inflammatory cytokines12
the integrity of the12
role in the induction12
morbidity and mortality in12
in influenza a virus12
clinical characteristics of cases12
have made a substantial12
to the generation of12
of the gut microbiota12
death in patients with12
outbreak associated with a11
and lower respiratory tract11
cd t cells may11
the expression of il11
are considered to be11
has been shown in11
of the host immune11
of c a and11
to be able to11
in an animal model11
there were no significant11
associated with a new11
innate immune response by11
of t cell responses11
increases the expression of11
presented in this study11
to acute respiratory distress11
t cells reactive to11
at the level of11
we did not observe11
in the blood of11
be responsible for the11
in line with this11
a new coronavirus of11
in patients with advanced11
influenza a and b11
causes and consequences of11
we have shown that11
cells from patients with11
on the immune system11
cd t cell frequencies11
group innate lymphoid cells11
suppressor of cytokine signaling11
to influenza virus infection11
are also involved in11
is a functional receptor11
the immune response is11
the crystal structure of11
has led to the11
a pneumonia outbreak associated11
and antigenicity of the11
pneumonia outbreak associated with11
of critically ill patients11
the authors showed that11
functional receptor for the11
are associated with the11
the context of the11
in the upper respiratory11
data were analyzed using11
in type diabetes mellitus11
airway epithelial cells and11
in a recent study11
phase i trial of11
in response to infection11
and the risk of11
little is known about11
production of proinflammatory cytokines11
the cytokine storm in11
of h n influenza11
with cd t cells11
related to the severity11
by type i ifn11
expressed on the surface11
to be essential for11
t cell activation and11
the vast majority of11
a decrease in the11
and their role in11
titer and genomic copy11
responses in the lung11
and genomic copy number11
the first trimester of11
approved by the ethics11
total cd t cells11
was also found to11
first trimester of pregnancy11
of th and th11
new coronavirus of probable11
of probable bat origin11
with the help of11
a functional receptor for11
naive cd t cells11
recent studies have shown11
plays a vital role11
will be required to11
plays a major role11
is also able to11
in the human placenta11
the end of the11
to be the case11
the importance of the11
to the control group11
the development of asthma11
the host innate immune11
mait cells in the11
have a role in11
shown to be involved11
and the severity of11
national institutes of health11
prevention and treatment of11
of rlr signaling pathway11
the case of sars11
have been reported in11
it was observed that11
are found in the11
the efficacy and safety11
in addition to these11
for the prevention and11
coronavirus of probable bat11
and neonatal alloimmune thrombocytopenia11
the pathogenesis of severe11
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after the onset of11
cytokine storm and immunopathology11
the immune system in11
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the identification of the11
higher than that of11
reduction and functional exhaustion11
g for min at11
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negative regulation of the11
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antigenicity of the sars11
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n influenza virus infection11
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advanced glycation end products11
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cells in the peripheral10
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material conflict of interest10
with middle east respiratory10
innate immune signaling pathways10
cells were then washed10
and interpretation of data10
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and natural killer cells10
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the inhibition of the10
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origins and receptor binding10
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intravenous immunoglobulin therapy in10
type i ifn in10
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immune response to sars10
implications for virus origins10
in human airway epithelial10
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lung injury in mice10
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t cells and nk10
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increase the expression of10
and adaptive immune cells10
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genomic characterisation and epidemiology10
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epidemiology of novel coronavirus10
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human cord blood igm10
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compared to patients with10
exhaustion of antiviral lymphocytes10
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cd or cd t10
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characterisation and epidemiology of10
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on the type of10
the antiviral immune response10
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have been identified as10
proinflammatory cytokines and chemokines10
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of genes involved in10
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linked ubiquitination of rig10
in peripheral blood mononuclear10
the safety and efficacy10
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of macrophage migration inhibitory9
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cd t cells after9
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challenged ttp myeko mice9
the course of the9
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recognition of viral rna9
live attenuated influenza vaccine9
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cd t cells specific9
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cd t cell counts9
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cellular and molecular mechanisms9
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respiratory syndrome coronavirus vaccine9
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to the use of9
the analysis of the9
a recent report by9
of cases of novel9
a phase clinical trial9
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consequences of cytokine storm9
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epidermal growth factor receptor9
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macrophage colony stimulating factor9
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cd effector t cells9
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viral load in the9
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patients with kawasaki disease9
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adult inpatients with covid8
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n influenza virus in8
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clinical course and risk8
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blockade of clec a8
of familial mediterranean fever8
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the ubiquitin ligase trim8
of t cell exhaustion8
cd t cell subpopulations8
of type diabetes mellitus8
to be the most8
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and middle east respiratory8
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adaptive immune response in8
the exact role of8
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of proinflammatory cytokines in8
parts of the world8
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early stage of infection8
important roles in the8
activation of the transcription8
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responses in the respiratory8
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highly pathogenic h n8
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clec a and tlr8
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cellular and humoral immunity8
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cell stimulatory mer peptides8
lymphocyte subsets in patients8
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cells in the pathogenesis8
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their role in the8
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role of dendritic cells8
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humoral and cellular immunity8
in human bronchial epithelial8
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goblet cell hyperplasia and8
formation of neutrophil extracellular8
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a high degree of8
to play a role8
recent study showed that8
food and drug administration8
class i and class8
course and risk factors8
patients with middle east8
of neutrophils in the8
it is noteworthy that8
treatment of patients with8
dipeptidyl peptidase iv in8
the release of inflammatory8
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the production of proinflammatory8
contribute to the induction8
activation and recruitment domains8
factors for mortality of8
it is worth noting8
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breadth of concomitant immune8
cord blood igm library8
patients with diabetes mellitus8
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one of the major8
and is involved in8
those induced by ifn8
were obtained from the8
that vitamin d supplementation8
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the remaining authors declare8
a mechanism by which8
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immunogenicity and safety of8
the rough endoplasmic reticulum8
chinese center for disease8
of pattern recognition receptors8
humoral and cellular immune8
a mouse model for8
significantly higher levels of8
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through the activation of8
t cell exhaustion during8
in human cd t8
host response to sars8
in the prefusion conformation8
infants and young children8
it is unknown whether8
suppressive activity of il8
one of the mechanisms8
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of dendritic cells and8
antibody germline maturation hypothesis8
human umbilical vein endothelial8
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acute respiratory syndrome in8
to the identification of8
of the severe acute8
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the antiviral activity of8
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coronavirus disease in china8
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cd cd regulatory t8
the inflammatory response to8
is reported to be8
high levels of ifn8
and characterization of the8
mhc class i peptide8
the important role of8
similar to those of8
the declaration of helsinki8
t cells and b8
is believed to be8
significant differences in the8
in c bl mice8
have also been used8
a significant reduction in8
the e ubiquitin ligase8
of the efficacy of8
cells were found to8
a consequence of the8
the author declares that8
the peripheral blood and8
at an early stage8
memory b cell responses8
shown to correlate with8
have been shown in8
in addition to their8
to determine whether the8
protein of influenza a8
was carried out in8
in the inhibition of8
is worth noting that8
of human influenza a8
the chinese center for8
resulted in a significant8
to the surface of8
the treatment of rheumatoid8
of different cell types8
by the severe acute8
might be due to8
t cells has been8
of this study was8
a variety of diseases8
with the potential to8
of the most common8
play a pivotal role8
outcomes in patients with8
targeting potential drivers of8
was performed as previously8
have been detected in8
cytotoxic t cell responses8
and memory cd t8
evolution of pathogenic coronaviruses8
was associated with the8
that are involved in8
derived human dendritic cells8
a key regulator of8
t cells contribute to8
the nuclear translocation of8
the main source of8
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activation of t cells8
t cells and the8
was carried out using8
that there is a8
mhc class i presentation8
immunology molecular innate immunity8
t cells that are8
have been used to8
malaria patients compared to8
cytokines such as tnf8
prior to patient recovery8
needed in order to8
replication of middle east8
of concomitant immune responses8
statistical analyses were performed8
type i ifn induction8
as a positive control8
infected with drv or8
myeloid differentiation primary response8
cells and b cells8
in the lower airways8
cd t cells has8
distress syndrome and death8
concomitant immune responses prior8
for the study of8
is the most common8
the female reproductive tract8
can be explained by8
by the novel coronavirus8
with fetal bovine serum8
has been correlated with8
and the generation of8
t lymphocyte subsets in8
found to be the8
of innate immune signaling8
innate immune system and8
antibody responses in covid8
and plasmacytoid dendritic cells8
that can be used8
risk factors for mortality8
card and rd regions8
in any of the8
to the maintenance of8
in the maintenance of8
to that of the8
for mortality of adult8
the s protein is8
and the control of8
the ethics committee of8
can be used for8
has been used to8
and are associated with8
entry of the virus8
to be important for8
seems to be a8
shown in figure b8
a protective role in8
in immunology molecular innate8
t cells play a8
responses prior to patient8
of which have been8
the protective effects of8
rd regions of zbrig8
disease is associated with8
are associated with increased8
with severe coronavirus disease8
human peripheral blood mononuclear8
in mhc class i8
group was injected with8
shown to be expressed8
an urgent need to8
in patients with kawasaki8
in the liver and8
adults hospitalized with severe8
compared to healthy donors8
in vitro studies have8
correlated with disease severity8
type i interferon in8
of angiotensin converting enzyme8
is a key factor8
t cell responses and8
with type i ifn8
mortality associated with influenza8
effective treatment of severe8
cells as compared to8
of chimeric antigen receptor8
might contribute to the8
with the supernatants from8
a therapeutic target in8
response to influenza vaccination8
between innate and adaptive8
subsequent development of asthma8
cd effector t cell8
blood of ms patients8
frontiers in immunology molecular8
involved in the pathophysiology8
and malaria patients compared8
to interfere with the8
multiple organ dysfunction syndrome8
at years of age8
that cd t cell8
in the bronchoalveolar lavage8
immunopathology on challenge with8
of th cells in8
in the antiviral response8
been identified as a8
of the designed vaccine8
the central role of8
cd t cells play8
has not yet been8
an increased production of8
following influenza virus infection8
of plasmacytoid dendritic cells8
as well as increased8
been shown to promote8
t cells to the8
c bl j mice8
was identified as the8
total rna was extracted8
and evolution of pathogenic8
the upper and lower8
has been attributed to8
in the lung tissue8
as a target for8
upregulated in response to8
cd t cells compared8
are highly susceptible to8
is known to be8
been detected in the8
em structure of the8
we and others have8
by respiratory syncytial virus8
case report of non8
for the initiation of8
the viral load in8
were significantly reduced in8
compared to the corresponding8
results suggest that the8
to note that the8
and type iii ifn8
found to be increased8
the start of the8
in the frequency of8
prevention and control of8
also be associated with8
by a variety of8
pathogenesis of severe acute8
protect the host from8
by the world health8
support corticosteroid treatment for8
increase in the number8
follicular helper t cells8
immune responses prior to8
as well as an8
hospitalized with severe covid8
response to the virus8
immunity to influenza a8
the antiviral effects of8
of sex hormones on8
dendritic cells and macrophages8
in patients with diabetes8
are the most abundant8
data are presented as8
of t cells reactive8
is a positive regulator8
for the design of8
in a subset of8
results indicate that the8
response against the virus8
may be able to8
centrifuged for min at8
clinical evidence does not8
vascular endothelial growth factor8
for the prevention of8
potential drivers of covid8
play a crucial role8
we will focus on8
used for the treatment8
patients with metastatic melanoma8
the potential use of8
be noted that the8
immune response against sars8
to the host cell8
written informed consent was8
diagnosis and treatment of8
effector memory cd t8
not support corticosteroid treatment8
shown to be a8
of patients with sars8
as well as il8
patients with t dm8
is considered to be8
the treatment of patients8
the development of new8
on monocytes and macrophages8
in the inflammatory response8
were washed three times8
observed in patients with8
data related to sars8
was used to determine8
antigen receptor t cells8
and an increase in8
does not support corticosteroid8
in the composition of8
acute lung injury and8
activation of nuclear factor8
of nontypeable haemophilus influenzae7
all authors approved the7
in response to virus7
the inflammatory response and7
risk factor for the7
accumulate preferentially in the7
specific memory t cells7
the datasets generated for7
the first months of7
the adoptive transfer of7
data indicate that the7
and important lessons from7
further studies are required7
and cd b in7
epitopes and their hla7
i ifn production by7
a vicious circle of7
as a positive regulator7
to be safe and7
human cd t cell7
the formation of a7
implications for pathogenesis and7
of vitamin d in7
in peripheral blood and7
for the identification of7
of the mechanisms by7
immunogenicity and protective efficacy7
of vitamin d supplementation7
which results in the7
an analysis based on7
with increased susceptibility to7
in mice with ibalt7
course and outcomes of7
the time course of7
syndrome and death in7
present on the surface7
young children with covid7
in multiple sclerosis and7
that are able to7
and mhc class ii7
the scope of this7
of genetics and physiology7
as well as cd7
of a combination of7
or in combination with7
form a complex with7
t cells are required7
a new coronavirus associated7
the subsequent development of7
of the ns protein7
plasma inflammatory cytokines and7
in the liver of7
laboratory of genetics and7
in mice and humans7
in the past years7
of natural killer cell7
we review the current7
a human monoclonal antibody7
type i ifn and7
for middle east respiratory7
the recruitment of neutrophils7
the extent to which7
for min on ice7
cases from the chinese7
the mavs signaling pathway7
studies have revealed that7
has a role in7
is not able to7
the critical role of7
against porcine reproductive and7
tumor necrosis factor receptor7
in multiple sclerosis lesions7
cd foxp regulatory t7
a vaccine based on7
of an inactivated vaccine7
production of inflammatory mediators7
of both innate and7
only a small proportion7
sex differences in the7
further research is needed7
accordance with the declaration7
there is an urgent7
propagation of infectious tolerance7
in the cerebrospinal fluid7
are known to be7
the role of nk7
has been previously shown7
t cells were not7
be directed to the7
peripheral blood of ms7
by innate immune cells7
the activation of innate7
new coronavirus associated with7
receptors on t cells7
the reduction of the7
cells are able to7
at high risk of7
for the emerging human7
immunized with pref advax7
macrophages or dendritic cells7
inflammatory responses in the7
of mortality due to7
t cells in both7
lower respiratory tract of7
an increased expression of7
health commission of the7
may play an important7
associated with an increase7
were added to the7
request to the corresponding7
can be attributed to7
cd t cells by7
in central nervous system7
in antiviral innate immunity7
dendritic cell subsets in7
be attributed to the7
of the disease is7
in the following sections7
trial of lopinavirritonavir in7
function of dendritic cells7
as severe acute respiratory7
tnf production in the7
has been used as7
groups were compared using7
the late stage of7
cell responses in the7
evade recognition by the7
the immune system to7
supplemented with fetal bovine7
for influenza virus replication7
and adaptive immune response7
modified vaccinia virus ankara7
h n infection in7
was inserted into the7
mechanisms of action of7
an increase in il7
on the s protein7
the incidence and severity7
risk of multiple sclerosis7
have the ability to7
of bronchoalveolar lavage fluid7
significantly higher than that7
the cell culture supernatants7
from patients with ild7
ncov spike in the7
inactivated severe acute respiratory7
the five types of7
with the severity of7
higher levels of il7
in the modulation of7
in the lung of7
high levels of the7
treatment of type diabetes7
available on request to7
were significantly lower than7
and transforming growth factor7
levels of proinflammatory cytokines7
in response to a7
a role for the7
a phase i study7
patients with mild covid7
study are available on7
alone and pref alum7
to the release of7
more common in the7
but not cd t7
to the ace receptor7
both human and mouse7
the use of an7
cd t cells mediate7
has been estimated that7
can be affected by7
to the nucleus and7
for the severity of7
and function of dendritic7
has proven to be7
at a concentration of7
of the inflammasome in7
over the past years7
induce the activation of7
also play a role7
outcomes of patients with7
from the chinese center7
as compared to lps7
of mice infected with7
against middle east respiratory7
a strong trend toward7
of the final vaccine7
infected with respiratory syncytial7
in response to different7
recognition by the host7
with a mortality rate7
feline infectious peritonitis virus7
samples were collected from7
supplemented with fbs and7
with the declaration of7
as well as other7
adaptive immune response to7
significant differences were observed7
in severely ill patients7
further inquiries can be7
and chemokines in severe7
differences between groups were7
our findings suggest that7
huh cells treated with7
more susceptible to the7
on the spike protein7
was further confirmed by7
for the evaluation of7
from patients with chronic7
gain access to the7
systemic inflammatory response syndrome7
infection was associated with7
is the first report7
nlrp inflammasome mediates in7
the production of cytokines7
the iuis vic toolkit7
cells were seeded in7
vivo innate immunity to7
may be mediated by7
novel coronavirus from wuhan7
case fatality rate of7
exacerbation of chronic obstructive7
in secondary lymphoid organs7
of caa and ccg7
innate immune cells in7
into the role of7
of mesenchymal stem cells7
of adaptive immune responses7
in the late stage7
in intestinal epithelial cells7
and revised the manuscript7
by japanese encephalitis virus7
presence of high levels7
to the expression of7
approved for the treatment7
the data showed that7
on taxonomy of viruses7
and rd regions of7
the t cell epitopes7
to the effects of7
and the supernatant was7
inflammation in patients with7
the propagation of infectious7
igg memory b cells7
for cd and cd7
the effects of vitamin7
receptor for the emerging7
a rat model of7
have also been observed7
a trial of lopinavirritonavir7
respiratory disease in china7
has been proposed as7
with severe respiratory failure7
of the plasma membrane7
both male and female7
human plasmacytoid dendritic cells7
rna pol iii alu7
effector memory t cells7
was supported by a7
associated with human respiratory7
a higher risk of7
during the early phase7
viral infection of the7
a pandemic by the7
was also detected in7
and functional characterization of7
were significantly higher than7
shown to contribute to7
the novel coronavirus from7
were incubated for min7
directed to the corresponding7
out in accordance with7
in addition to this7
binding to its receptor7
the length of the7
syndrome coronavirus infection in7
cells of patients with7
inflammasome mediates in vivo7
type i interferon antiviral7
as well as by7
and the control group7
proteases tmprss and hat7
this study are available7
the specificity of the7
pref alone and pref7
production as well as7
increased serum levels of7
in the female reproductive7
consent was obtained from7
cd t cell depletion7
the effect of the7
in the lower airway7
the activation of th7
chinese academy of sciences7
both type i and7
shown to be upregulated7
was used to predict7
shown to increase the7
and adaptive immune system7
both p and jnk7
t cells have been7
tlr and tlr are7
and b cell epitopes7
ar and c ar7
the airway epithelium is7
of the epithelial barrier7
cells such as macrophages7
committee on taxonomy of7
the vitamin d receptor7
human respiratory disease in7
we demonstrated that the7
course of siv infection7
in the lung airways7
virus through recognition of7
cells in vitro and7
which can lead to7
resident memory cd t7
i ifn production in7
of science and technology7
clinical course and outcomes7
systemic juvenile idiopathic arthritis7
c ar and c7
h after lps challenge7
in light of the7
of activated cd t7
n or h n7
may be related to7
heavy and light chains7
the international committee on7
the chinese academy of7
the neonatal immune system7
of nk cells to7
is the result of7
cells treated with ifn7
the immunomodulatory effects of7
may be beneficial in7
in the control group7
no serious adverse events7
nk cells and cd7
tlr and tlr in7
and one of the7
of human bronchial epithelial7
the induction of the7
blood mononuclear cells in7
the false discovery rate7
dna and rna viruses7
of the upper respiratory7
in the field of7
our data suggested that7
structural studies of sars7
the outcome of the7
can be activated by7
cell epitopes and their7
sepsis and septic shock7
cells are activated by7
of lopinavirritonavir in adults7
to the hypothesis that7
in the prevention of7
haddock clustered structures in7
production by cd t7
mode of action of7
these results indicated that7
coronavirus associated with human7