trigram

This is a table of type trigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

trigram	frequency
a h n	107
respiratory syndrome coronavirus	91
p m e	82
east respiratory syndrome	76
middle east respiratory	76
severe acute respiratory	65
cov m protein	64
in this study	62
acute respiratory syndrome	58
the presence of	55
as well as	51
h n influenza	47
h n virus	47
according to the	42
the detection of	42
emerg microbes infect	41
microbes infect doi	41
influenza a h	40
influenza a virus	37
the cells were	36
based on the	36
detected in the	35
hepatitis c virus	34
of influenza a	34
avian influenza a	34
of a novel	31
of respiratory viruses	31
the united states	31
one of the	30
the emergence of	30
due to the	30
was detected in	30
emerging infectious diseases	29
of c a	29
of the virus	27
of h n	27
of severe acute	27
of middle east	27
a total of	26
and characterization of	26
patients infected with	26
in the united	26
a novel coronavirus	26
in our study	26
the development of	25
h n and	25
acute lung injury	24
in addition to	23
role in the	23
the h n	22
the control group	22
has been reported	22
of porcine deltacoronavirus	21
for h at	21
h n viruses	20
characterization of a	20
of zika virus	20
world health organization	20
west nile virus	20
was reported by	20
was performed using	20
were detected in	20
of the viral	20
polymerase chain reaction	20
for the detection	19
most of the	19
in order to	19
a and b	19
of novel coronavirus	19
cells were washed	19
in saudi arabia	19
the middle east	19
been reported in	19
detection of respiratory	19
of avian influenza	18
during the hajj	18
in hong kong	18
as shown in	18
n influenza virus	18
for min at	18
host cell entry	18
avian influenza viruses	18
influenza a viruses	17
in the present	17
potential conflict of	17
samples were collected	17
influenza virus infection	17
e and p	17
and h n	17
there is no	17
for respiratory viruses	17
no potential conflict	17
reported by the	17
closely related to	17
need to be	17
found to be	17
conflict of interest	17
m e and	17
viral rna in	17
novel goose astrovirus	17
of interest was	17
respiratory syncytial virus	17
interest was reported	17
analysis of the	16
the present study	16
in the same	16
of the two	16
to determine the	16
empty expression vector	16
genome sequence of	16
was used to	16
balb c mice	16
m e dna	16
of hepatitis c	16
in the control	16
in the presence	16
of the mers	16
the role of	16
showed that the	16
human monoclonal antibody	16
virus infection in	16
of coronavirus hku	15
the ability of	15
in st cells	15
in patients with	15
patients with a	15
pathogenic avian influenza	15
this study was	15
highly pathogenic avian	15
with h n	15
of viral rna	15
and st cells	15
the number of	15
were infected with	15
isolation and characterization	15
was used as	14
the diagnosis of	14
viral rna was	14
a role in	14
cov and mers	14
of enterovirus d	14
the virus was	14
than that of	14
and incubated for	14
included in the	14
have been reported	14
of the study	14
by highly pathogenic	14
of patients with	14
associated with human	14
upper respiratory tract	14
h n infection	14
data not shown	14
we found that	14
public health laboratories	14
of public health	14
hpai h n	14
avian influenza virus	14
of infectious diseases	14
as previously described	13
the novel goose	13
to evaluate the	13
of a h	13
the time of	13
lower respiratory tract	13
at the time	13
the pathogenesis of	13
were collected from	13
as described previously	13
associated with a	13
admitted to the	13
for detection of	13
clinical characteristics of	13
genbank accession number	13
of the patients	13
supplementary figure s	13
rna was detected	13
for disease control	13
zika virus in	13
respiratory disease in	13
complete genome sequence	13
h n strains	13
respiratory tract infections	13
for influenza a	13
patients with respiratory	13
disease control and	12
in h n	12
at room temperature	12
was associated with	12
the respiratory tract	12
influenza h n	12
b and c	12
were performed using	12
was found to	12
the use of	12
approved by the	12
antiviral immune responses	12
related to the	12
responsible for the	12
that of the	12
to the icu	12
three times with	12
cells transfected with	12
of respiratory infection	12
control and prevention	12
zika virus infection	12
observed in the	12
some of the	12
shown in figure	12
mice in the	12
incubated for h	12
pk and st	12
in the blood	12
performed using the	12
phylogenetic analysis of	12
an important role	12
tested positive for	12
liver and kidney	12
the majority of	12
compared with bar	11
the expression of	11
in dromedary camels	11
induced by highly	11
risk factors for	11
compared to the	11
found in the	11
were found to	11
respiratory viruses in	11
the m protein	11
highly pathogenic virus	11
the world health	11
understanding of the	11
associated with the	11
in the future	11
the identification of	11
respiratory pathogen panel	11
rna was extracted	11
were subjected to	11
from patients with	11
be detected in	11
of the world	11
rna in the	11
n and a	11
novel coronavirus from	11
porcine epidemic diarrhea	11
in the study	11
the lack of	11
for the first	11
lower than that	11
of influenza virus	11
of respiratory pathogens	11
been detected in	11
the outbreak period	11
the risk of	11
m protein was	11
national public health	11
terminal transmembrane domains	11
an outbreak of	11
the patients with	10
influenza viruses in	10
a history of	10
the importance of	10
the m e	10
with pneumonia in	10
been reported to	10
humoral and cellular	10
of the novel	10
to the liver	10
m protein is	10
part of the	10
important role in	10
a number of	10
isolated from a	10
porcine deltacoronavirus strain	10
washed with pbs	10
in the pathogenesis	10
identified in the	10
in humans and	10
nxtag respiratory pathogen	10
is associated with	10
cells were infected	10
suggesting that the	10
the infected goslings	10
virus h n	10
a variety of	10
at least one	10
immune responses in	10
viral load in	10
play a role	10
and phylogenetic analysis	10
pcr products were	10
of the infected	10
in the first	10
morbidity and mortality	10
the viral load	10
with pbs and	10
innate antiviral response	10
a critical role	10
driven host cell	10
by the author	10
with that of	10
that c a	10
of the disease	10
and a h	10
parts of the	10
highly pathogenic viruses	10
as described above	10
the formation of	10
the occurrence of	10
be able to	10
positive for influenza	10
the group of	10
the activation of	10
human infection with	10
human monoclonal antibodies	10
have also been	10
during the outbreak	9
influenza virus a	9
oxygen supply to	9
have been detected	9
c a and	9
in the case	9
of hh in	9
coronavirus hku was	9
the collection of	9
for diagnosis of	9
of emerging infectious	9
in accordance with	9
results suggest that	9
are susceptible to	9
supply to the	9
in pbs bsa	9
avian influenza h	9
against influenza virus	9
the induction of	9
of west nile	9
the viral genome	9
m protein in	9
of m e	9
with or without	9
was supported by	9
innate immune response	9
was performed as	9
used as a	9
promotes pdcov replication	9
respiratory tract infection	9
in the saliva	9
the onset of	9
is the first	9
sequences of the	9
and incubated at	9
h n infections	9
taken from the	9
and ns b	9
porcine deltacoronavirus in	9
the complete genome	9
amino acid residues	9
extracted from the	9
ha and na	9
the context of	9
it has been	9
was found in	9
and treatment of	9
c a antibody	9
in wild chimpanzees	9
on the other	9
science and technology	9
there was no	9
consistent with the	9
cytokines such as	9
be found in	9
in the context	9
it is not	9
cd t cells	9
n and h	9
the novel coronavirus	9
the samples were	9
in the npa	9
in patients infected	9
been shown to	9
were included in	9
trypsin promotes pdcov	9
of the respiratory	9
isolation of a	9
cellular immune responses	9
viral respiratory pathogens	9
the e protein	9
to that of	9
of neutralizing antibodies	8
majority of the	8
the administration of	8
supplementary table s	8
end of the	8
c a is	8
were transfected with	8
led to the	8
of a new	8
cd and cd	8
the other hand	8
the arabian peninsula	8
this work was	8
the supernatant was	8
revealed that the	8
genetic characterization of	8
type i interferon	8
pilgrims during the	8
e dna vaccine	8
after symptom onset	8
identification of a	8
cov s binding	8
to be further	8
neutralizing activity of	8
of the first	8
out of the	8
for a h	8
the discovery of	8
the npa and	8
data suggest that	8
n influenza viruses	8
and public health	8
virus in the	8
the carriage of	8
in contrast to	8
was carried out	8
were obtained from	8
indicating that the	8
are responsible for	8
serum samples were	8
was isolated from	8
at day post	8
influenza virus h	8
c a in	8
samples of pigs	8
the presence or	8
optimized m e	8
to be the	8
present in the	8
isolated from the	8
medical college hospital	8
collected from the	8
round primers lpw	8
and cellular immune	8
comparison of the	8
regions of the	8
there was a	8
with acute respiratory	8
detection of sars	8
of the isolate	8
h n in	8
similar to the	8
respiratory distress syndrome	8
cells were transfected	8
the study was	8
of the most	8
with highly pathogenic	8
cov and sars	8
to be a	8
was set as	8
the causative agent	8
the first time	8
are associated with	8
pdcov replication in	8
at h post	8
the isolation of	8
changes in the	8
from the same	8
the patient had	8
primers lpw lpw	8
to cells expressing	8
high levels of	8
sequence of porcine	8
nile virus in	8
in the putative	8
live bird markets	8
the absence of	8
chronic respiratory disease	8
union medical college	8
a crucial role	8
and c a	8
with influenza a	8
or mutant dpp	8
was approved by	8
was added to	8
critical role in	8
disease in china	8
cells were further	8
could not be	8
the prevalence of	8
avian h n	8
peking union medical	8
may be a	8
for h n	8
or empty expression	8
the spread of	8
can be used	8
presence of the	7
coronavirus hku in	7
virus in a	7
washed three times	7
were washed with	7
and genetic characterization	7
centers for disease	7
results show that	7
severe liver impairment	7
patients with pneumonia	7
the surface of	7
cells were then	7
times with pbs	7
in the lung	7
the binding of	7
of this virus	7
a previous study	7
in the viral	7
viral load and	7
increase in the	7
added to the	7
the severe acute	7
the upper respiratory	7
npa and saliva	7
appears to be	7
contribute to the	7
differences in the	7
memory b cells	7
our understanding of	7
members of the	7
consistent with previous	7
we did not	7
were found in	7
of human origin	7
transfected with expression	7
detection and characterization	7
c a receptor	7
h n avian	7
against zika virus	7
mice infected with	7
clinical management of	7
syndrome coronavirus infection	7
all of the	7
the virus in	7
the treatment of	7
coronavirus associated with	7
results indicate that	7
expression vectors for	7
n influenza a	7
cases of respiratory	7
by the authors	7
adaptive immune response	7
we used a	7
been implicated in	7
neutrophil extracellular traps	7
detection of influenza	7
patients with severe	7
the amino acid	7
zikv infection in	7
infected cells were	7
m e immunization	7
the production of	7
the virus may	7
epidemic diarrhea virus	7
residues in the	7
to those of	7
weeks after the	7
clinical features of	7
on the surface	7
characterization of the	7
cd t cell	7
of patients infected	7
infected with pdcov	7
of hong kong	7
similar to that	7
respiratory viruses and	7
domain of the	7
respiratory virus infection	7
bronchoalveolar lavage fluid	7
respiratory tracts of	7
transmission of the	7
patients whose npa	7
and the cells	7
revealed the presence	7
viral replication and	7
were positive for	7
to investigate the	7
crucial role in	7
of the flaviviridae	7
nature of the	7
and control of	7
coronavirus from a	7
dromedary camels in	7
higher than that	7
and l q	7
possible lrti symptoms	7
of the samples	7
was extracted from	7
a new coronavirus	7
had a history	7
zikv e protein	7
that of sars	7
viral load was	7
results indicated that	7
more than one	7
from a dromedary	7
the course of	7
in emerging infectious	7
clinical signs in	7
disease in humans	7
other parts of	7
in the human	7
specimens from the	7
insights into the	7
and emergence of	7
considered to be	7
viral loads in	7
was performed in	7
and cd t	7
intensive care unit	7
ngogo and kanyawara	7
ns and ns	7
the nxtag respiratory	7
of nipah virus	7
most closely related	7
respiratory viruses by	7
of human infection	7
sparrow cov hku	7
hepatitis b virus	7
cell membrane fusion	7
and the other	7
a result of	7
in response to	7
these results suggest	7
and the relative	7
was identified in	7
prevalence of hh	7
patients with acute	7
was used for	7
institute of virology	7
development of vaccines	7
g for min	7
the transmission of	7
wt or mutant	7
the fact that	7
the detection rate	7
of the m	7
e and ns	7
plays a critical	7
of antiviral mabs	7
the amount of	6
a and c	6
in the upper	6
at least two	6
d was the	6
m e group	6
member of the	6
this suggests that	6
n virus in	6
can be found	6
the end of	6
coronaviruses as the	6
infectious diseases in	6
immunized three times	6
in the genus	6
serve as a	6
the case group	6
carried out using	6
positive for respiratory	6
a recent study	6
been found to	6
circulation of a	6
from the infected	6
is essential for	6
specific cd t	6
been tested in	6
likely to be	6
and u l	6
is consistent with	6
center for disease	6
he was transferred	6
to further confirm	6
cause of death	6
the cases of	6
set as and	6
white blood cell	6
resulted in a	6
the isolate was	6
diagnosis of respiratory	6
followed by a	6
st cells were	6
present dromedary wnv	6
should be considered	6
has been tested	6
borne encephalitis virus	6
in balb c	6
human c a	6
the present dromedary	6
presence or absence	6
found that the	6
after viral challenge	6
virus was detected	6
for the diagnosis	6
has not been	6
the ngogo and	6
genomic characterization of	6
involved in the	6
urine and saliva	6
potent neutralization of	6
and avian coronaviruses	6
against h n	6
a man with	6
only a few	6
have been identified	6
of the outbreak	6
of lineage a	6
study was approved	6
antibodies isolated from	6
to assess the	6
outbreak associated with	6
the ha of	6
were used as	6
trypsin for h	6
antibody responses were	6
has also been	6
mammalian and avian	6
open reading frames	6
high prevalence of	6
human infections with	6
of these patients	6
pneumonia in saudi	6
two of the	6
analysis of variance	6
with empty expression	6
used as the	6
further studies are	6
and the first	6
in the respiratory	6
gene source of	6
viral transport medium	6
to interact with	6
antiviral immune response	6
in both the	6
pdcov infection in	6
acquisition of respiratory	6
orf b and	6
with avian influenza	6
contigs assigned to	6
from a man	6
of the genome	6
lead to the	6
as and the	6
in the lungs	6
in recent years	6
from the control	6
the most frequent	6
sequencing of the	6
acute flaccid myelitis	6
for the development	6
viruses detected in	6
is one of	6
and their families	6
and the saliva	6
national health commission	6
vesicular stomatitis virus	6
such as a	6
swab samples were	6
of the new	6
were centrifuged at	6
respiratory tract specimens	6
specimens taken from	6
ranged from to	6
addition to the	6
the gout disease	6
and in the	6
such as the	6
kibale national park	6
the effect of	6
cluster of lineage	6
or absence of	6
the potential to	6
throughout the year	6
in the middle	6
detected in of	6
viruses in the	6
to identify the	6
of infectious disease	6
in the absence	6
to the emergence	6
acute respiratory disease	6
is possible that	6
compared with that	6
shown in table	6
care and use	6
to understand the	6
the gene source	6
work was supported	6
lane compared with	6
virus infection by	6
m e was	6
novel human coronavirus	6
of trypsin at	6
with a novel	6
of unexplained pneumonia	6
the most potent	6
viral n protein	6
such as il	6
human h n	6
that the virus	6
used for the	6
structure of the	6
been associated with	6
day post infection	6
region of the	6
by flow cytometry	6
the release of	6
wuhan institute of	6
vitro and in	6
taxonomy of viruses	6
from all samples	6
carcass wash water	6
should be performed	6
complete genome sequencing	6
expression of the	6
development of a	6
n avian influenza	6
infection in the	6
in the nasopharynx	6
as described in	6
of vaccines and	6
shown in fig	6
induced acute lung	6
way analysis of	6
with expression vectors	6
in vitro and	6
were used for	6
time reverse transcription	6
monoclonal antibody against	6
in the usa	6
it is possible	6
virus may be	6
have not been	6
the genomes of	6
supported by the	6
indicated that the	6
were purchased from	6
to our knowledge	6
in fecal samples	6
was added and	6
a is a	6
transferred to the	6
novel coronavirus in	6
ics made with	6
v g and	6
been reported that	6
suggest that the	6
the saliva specimens	6
in the two	6
severe liver injury	6
pcr for the	6
live poultry markets	6
experimental infection of	6
enterovirus d in	6
were analyzed by	6
man with pneumonia	6
in north america	6
western blot analysis	6
influenzae and m	6
pcr was performed	6
the origin of	6
after h n	6
the pcr products	6
are needed to	6
and subjected to	6
at the hajj	6
humans and animals	6
presence of viral	6
in respiratory samples	6
is a strong	6
of these viruses	6
the dynamics of	6
infection with a	6
whose npa specimens	6
gout disease in	6
to e protein	6
during the same	6
a or b	6
terminal domain of	6
that trypsin promotes	6
g and l	6
binding to dpp	6
the patient was	6
from a patient	6
as the gene	6
were further incubated	6
detection of a	6
transmission to humans	6
the case of	6
because of the	6
with the same	6
the existence of	6
transcription polymerase chain	6
activity of the	6
in which the	6
phylogenetic tree was	6
old goslings were	6
days and and	6
is important for	6
in the second	6
of the h	6
the human population	6
of respiratory disease	6
shortness of breath	6
acute respiratory infections	6
the impact of	6
dpp surface expression	6
this work is	6
the spike protein	6
neutralizing monoclonal antibodies	6
coronavirus hku strains	6
associated with severe	6
pdcov in the	6
four spdcov strains	6
the university of	6
is similar to	6
cloned into the	6
there is a	6
causative agent of	6
molecular and serological	6
our results show	6
analytical diagnostic laboratories	6
of prv m	6
which is a	6
m protein with	6
influenza b virus	6
may not be	6
the international committee	6
molecular characterization of	6
the control groups	6
of antiviral immune	6
remains to be	6
used in this	6
accordance with the	6
the anal swab	6
the evolution of	6
the current study	6
in cultured cells	5
binding to the	5
the plates were	5
a prospective cohort	5
any of the	5
in severe cases	5
in hubei province	5
and evolution of	5
the nasopharyngeal samples	5
in the brain	5
infected patients with	5
pandemic h n	5
pk cells at	5
neutralizing monoclonal antibody	5
is known to	5
samples from a	5
children and their	5
of the pcr	5
in line with	5
spread of the	5
complete blood count	5
pigs in hong	5
in combination with	5
were collected for	5
tested negative for	5
of contact with	5
we performed a	5
to a h	5
h n isolates	5
a study of	5
the host immune	5
mutant dpp was	5
activity of hnigga	5
influenza virus infections	5
the s subunit	5
detected in respiratory	5
or a p	5
of the manuscript	5
c a might	5
the c a	5
agnostic hts analysis	5
implications for pathogenesis	5
days after symptom	5
is likely to	5
s binding to	5
total rna was	5
the two nasopharyngeal	5
and in vivo	5
chinese academy of	5
the innate immune	5
dilution in pbs	5
viruses of human	5
outbreaks in the	5
previous studies have	5
the extent of	5
of viruses that	5
evolutionary genetics analysis	5
at an moi	5
the phylogenetic tree	5
these results indicate	5
mice immunized with	5
a descriptive study	5
the complement system	5
located in the	5
the putative e	5
in t cells	5
the culture medium	5
by grants from	5
is the most	5
only detected in	5
goose hemorrhagic polyomavirus	5
further incubated for	5
in the cell	5
patients who tested	5
in the infected	5
positive for sars	5
for arbovirus control	5
leading cause of	5
resuspended in pbs	5
high degree of	5
national reference laboratory	5
viruses have been	5
further confirm the	5
management of severe	5
highly pathogenic viral	5
the most effective	5
viruses that infect	5
the negative control	5
in acute lung	5
history of contact	5
on days and	5
in the field	5
day after h	5
nucleic acid test	5
may lead to	5
the aim of	5
the effectiveness of	5
a dromedary calf	5
pk cells were	5
a novel human	5
the ha and	5
disease in wild	5
of wnv in	5
with respect to	5
stage of the	5
protective efficacy of	5
and target cells	5
phylogenetic trees were	5
n virus infection	5
the influenza virus	5
emergence of new	5
second part of	5
cov spike protein	5
to pdcov infection	5
molecular evolutionary genetics	5
viruses that are	5
virus isolation and	5
were washed three	5
in this article	5
subtracted from all	5
and a p	5
in oral swabs	5
ability of the	5
monoclonal antibodies against	5
with zika virus	5
than that in	5
the most recent	5
human transmission of	5
no significant difference	5
in out of	5
isolation and propagation	5
respiratory infections in	5
alone or in	5
cell responses in	5
personal protective equipment	5
in live bird	5
were defined as	5
play a crucial	5
serological evidence of	5
for the presence	5
t cells were	5
syndrome coronavirus and	5
with the novel	5
of variance with	5
the cell surface	5
in vero cells	5
the novel human	5
of cases of	5
cov s to	5
irf and nf	5
h n challenge	5
viruses and bacteria	5
compared with lane	5
the species barrier	5
to in the	5
the neutralizing activity	5
but not in	5
contributed to the	5
titers in the	5
acute respiratory distress	5
of the ev	5
igm and igg	5
contributes to the	5
like circular virus	5
that zikv can	5
animal models of	5
none of the	5
h n pandemic	5
effector cells were	5
among hajj pilgrims	5
were admitted to	5
zika virus and	5
human immunodeficiency virus	5
the second part	5
open reading frame	5
academy of sciences	5
protein is a	5
infection in mice	5
of sars coronavirus	5
were treated with	5
mpv and hrv	5
cell entry and	5
human a h	5
nucleic acid amplification	5
that in the	5
icu patients with	5
infected with highly	5
load in the	5
japanese encephalitis virus	5
republic of china	5
hepatitis e virus	5
and clinical characteristics	5
and the cellular	5
shown to be	5
infection has been	5
avian influenza strains	5
which is consistent	5
prevention and control	5
was calculated accordingly	5
broadly neutralizing antibodies	5
m e protein	5
for s and	5
be due to	5
of the p	5
and the effect	5
of acute respiratory	5
the vast majority	5
the two patients	5
were incubated at	5
and pathogenesis of	5
is able to	5
in sars patients	5
were observed in	5
length genome sequence	5
absence of trypsin	5
the possibility that	5
diagnosis and treatment	5
from to in	5
died within days	5
for the binding	5
polymorphisms in dpp	5
sequence of the	5
a virus m	5
inflammatory cytokines such	5
host innate antiviral	5
could also be	5
of the following	5
bird markets in	5
are likely to	5
immunized with p	5
as a h	5
two patients with	5
in the serum	5
with human ace	5
first isolated in	5
of human infections	5
no role in	5
the four spdcov	5
there were no	5
of s protein	5
the genbank database	5
of dpp surface	5
was defined as	5
neutralizing antibodies and	5
genomes of the	5
that the isolate	5
in the region	5
between respiratory pathogens	5
an moi of	5
trypsin was added	5
the convalescent sera	5
in cell culture	5
samples collected from	5
the addition of	5
to further investigate	5
of virus rna	5
the common cold	5
role of c	5
the differences in	5
public health reference	5
h post transfection	5
influenza viruses were	5
pathogens in the	5
we demonstrated that	5
to be infected	5
the other two	5
infected with h	5
in one of	5
the interaction of	5
transfected with empty	5
identification of the	5
for each sample	5
amino acid substitutions	5
to enhance the	5
discovery of a	5
the virus is	5
in these samples	5
were added to	5
features of patients	5
porcine deltacoronavirus from	5
during the study	5
at the cell	5
respiratory illness associated	5
different types of	5
specific antibody responses	5
the antiviral immune	5
to the viral	5
of the positive	5
and supplementary table	5
was able to	5
illness associated with	5
of respiratory virus	5
in the country	5
e and e	5
from march to	5
virus associated with	5
hepatitis g virus	5
the sequences of	5
did not show	5
in the ns	5
a creative commons	5
swabs were collected	5
in upper respiratory	5
respiratory syndrome and	5
a lack of	5
from the national	5
of antibody responses	5
in the last	5
in the non	5
for min and	5
obtained from the	5
reported in the	5
virus m protein	5
infections in humans	5
with respiratory infections	5
npa and the	5
was detected by	5
high level of	5
under a creative	5
infection in a	5
critically ill patients	5
to the lack	5
and found that	5
this is the	5
outbreaks of respiratory	5
the lungs of	5
the nature of	5
clinical signs and	5
heavy and light	5
of the nasopharyngeal	5
are expressed as	5
to test whether	5
the susceptibility of	5
patient had a	5
amino acid sequence	5
was subtracted from	5
the outbreak of	5
by the national	5
susceptible to pdcov	5
belonging to the	5
an h n	5
ali induced by	5
of the immune	5
were reported in	5
gosling gout disease	5
in the p	5
a systematic review	5
based on a	5
the prevention of	5
respiratory tract of	5
that it is	5
was not detected	5
in the current	5
to be positive	5
routine clinical testing	5
replication in llc	5
from children with	5
from species a	5
than in the	5
the host innate	5
of the sars	5
emerging viral diseases	5
had no role	5
in the anal	5
was first isolated	5
from the united	5
lunar new year	5
in the spike	5
infection in humans	5
respiratory viral pathogens	5
in south america	5
nucleic acid extraction	5
cohort of patients	5
ha of h	5
from infected cells	5
a causative agent	5
was obtained from	5
the host cell	5
well as the	5
our study is	5
h at room	5
the difference in	5
astrovirus associated with	5
has been implicated	5
outbreak of severe	5
c a signaling	5
the digestive tract	5
for the prevention	5
alternatively known as	5
clades a and	5
plays an important	5
a set of	5
of the supernatant	5
predicted to encode	5
public health laboratory	5
saliva specimens were	5
the same period	5
health commission of	5
of all samples	5
the flaviviridae family	5
cov strain hku	5
respiratory virus infections	5
ethics committee of	5
of respiratory symptoms	5
were able to	5
was identified as	5
h n cases	5
further investigate the	5
the sensitivity of	5
cases were detected	5
analysis of porcine	5
carried out in	4
the distribution of	4
also been reported	4
the inhibition of	4
for patients with	4
the s protein	4
may be able	4
of the human	4
as a result	4
be associated with	4
goose astrovirus gd	4
with those of	4
to viruses that	4
to investigate whether	4
efficacy of a	4
had been vaccinated	4
comparative analysis of	4
a p and	4
dromedaries in the	4
has been widely	4
a high prevalence	4
natural science foundation	4
e gene sequences	4
new coronavirus of	4
the possibility of	4
with other known	4
characterization of an	4
second round primers	4
molecular epidemiology of	4
signs of disease	4
and risk factors	4
should not be	4
mice were immunized	4
the hospital stay	4
virus could be	4
samples tested positive	4
have the potential	4
pandemic influenza a	4
an intermediate host	4
and anal swab	4
consent was obtained	4
the npa specimens	4
coronavirus infection in	4
coronavirus from patients	4
for quantification of	4
the isolation and	4
of the total	4
all the infected	4
confirmed to be	4
loads in the	4
and detection of	4
in cluster of	4
inflammatory cell migration	4
among pilgrims during	4
significantly lower than	4
early transmission dynamics	4
obstructive pulmonary disease	4
of differences in	4
amino acid sequences	4
the structure of	4
prospective cohort of	4
difference in the	4
domain of sars	4
during the hospital	4
admission to the	4
from the group	4
of the influenza	4
simultaneous outbreaks of	4
first round primers	4
detected during the	4
copies per ml	4
in the ctb	4
the reaction was	4
nested pcr using	4
structural proteins ns	4
oral swabs positive	4
caused by the	4
neutralizing human monoclonal	4
public health diagnostic	4
be used as	4
role in study	4
international committee on	4
receptor binding domain	4
to note that	4
strains identified in	4
in most of	4
medium was added	4
interact with mers	4
incidence of hh	4
antigen presentation by	4
pdcov replication at	4
a better understanding	4
we developed a	4
a patient with	4
the brain and	4
saliva in addition	4
of infected individuals	4
influenza a and	4
studies demonstrated that	4
from the cases	4
in anal swab	4
needs to be	4
analysis was performed	4
this is in	4
of the three	4
detectable viral rna	4
without trypsin for	4
catarrhalis carriage was	4
strains in the	4
leading to the	4
two nasopharyngeal strains	4
and staphylococcus aureus	4
on illness day	4
of this license	4
viral titer in	4
in anal swabs	4
functional receptor for	4
of inflammatory cytokines	4
french pilgrims during	4
the cell culture	4
was transferred out	4
cases of middle	4
the enhancement of	4
has been associated	4
pdcov replication by	4
pcr using first	4
of a pandemic	4
of severe liver	4
each of the	4
that there were	4
by using the	4
h n patients	4
chronic heart disease	4
considered to have	4
syndrome caused by	4
significant difference in	4
state of the	4
did not have	4
in humans in	4
considered statistically significant	4
of which were	4
the cytoplasm of	4
and influenza viruses	4
minimum essential medium	4
proportion of patients	4
studies are needed	4
the idea that	4
because it is	4
and challenges for	4
the next pandemic	4
result in the	4
is predicted to	4
was the only	4
coronavirus hku may	4
in the family	4
pcr in the	4
demonstrated that the	4
is a major	4
to the hospital	4
control g liang	4
virus infection a	4
and rectal swabs	4
depends on the	4
h avian influenza	4
of avian nephritis	4
of the control	4
with respiratory virus	4
coronavirus study group	4
were identified by	4
sequence of a	4
more than two	4
respiratory syndrome virus	4
viruses such as	4
liang et al	4
min at room	4
better understanding of	4
university of hong	4
adult patients with	4
the liver and	4
effect of c	4
cells expressing dpp	4
the notion that	4
forward and reverse	4
cov m proteins	4
added and incubated	4
first transmembrane domain	4
the first isolation	4
in the past	4
in the world	4
the goose astrovirus	4
pbs and then	4
was analyzed by	4
m e immunized	4
low pathogenic avian	4
were responsible for	4
was amplified by	4
were inoculated with	4
of bat origin	4
of zikv infection	4
vectors for wt	4
antibodies targeting the	4
the african continent	4
permeability of the	4
d was detected	4
necessary to develop	4
g liang et	4
were mixed with	4
viral infections and	4
respiratory illness in	4
is a type	4
the three patients	4
c a induces	4
is highly conserved	4
science foundation of	4
diseases such as	4
severe respiratory illness	4
with novel coronavirus	4
the same time	4
in the pharyngeal	4
a cytokine storm	4
the likelihood of	4
emerging infectious disease	4
as described for	4
mouse model of	4
health laboratories in	4
high viral loads	4
to zikv e	4
benefit of testing	4
virus was identified	4
been found in	4
genome sequences were	4
in the clinical	4
in the supernatant	4
of porcine epidemic	4
the pathogenicity of	4
characteristics of cases	4
to support the	4
the newly identified	4
first isolation of	4
performed using a	4
and did not	4
acute respiratory tract	4
visceral urate deposition	4
from h n	4
innate immune cells	4
to develop a	4
which has been	4
the virus and	4
play an important	4
in a human	4
are similar to	4
analyzed by flow	4
t cells and	4
described in fig	4
evidence for a	4
respiratory disease outbreak	4
who tested positive	4
interact with the	4
respiratory viral pathogen	4
impact on the	4
the specimens from	4
cells were seeded	4
creative commons license	4
the membranes were	4
protein and the	4
for virus shedding	4
genetic diversity and	4
have already been	4
or in combination	4
fecal samples of	4
it is important	4
of the main	4
pdcov infection than	4
detected in a	4
addition to npa	4
evaluation of the	4
carriage of h	4
relative to the	4
domain complexed with	4
consisted of patients	4
potential of antiviral	4
over the past	4
were infected by	4
the association between	4
dynamics in wuhan	4
upper and lower	4
effector and target	4
unexplained cases of	4
of the causative	4
a negative control	4
a source of	4
the dromedary wnv	4
increased levels of	4
tree was constructed	4
these samples were	4
respiratory viruses was	4
fragment of the	4
neutralizing activities against	4
identification and characterization	4
the viral propagation	4
patients with sars	4
to play a	4
with the indicated	4
performed as previously	4
prophylactic and therapeutic	4
data analysis was	4
preclinical models of	4
the data suggest	4
to the fc	4
from each group	4
viral rna mini	4
listed in table	4
the funders had	4
transmission caused by	4
from the diseased	4
association between the	4
brain and spleen	4
is not a	4
view a copy	4
and second round	4
of the coronavirus	4
assay for detection	4
individual preventive measures	4
work is licensed	4
and antibody responses	4
we thank all	4
in the structural	4
m e to	4
reported that the	4
medium was replaced	4
detection of antibodies	4
implicated in neuroinvasiveness	4
the preparation of	4
on the arabian	4
e protein was	4
in different mammalian	4
ncov infected patients	4
e or a	4
complete genome of	4
amplified by pcr	4
against mers coronavirus	4
antibodies were detected	4
with a respiratory	4
responses by ics	4
a final extension	4
the e gene	4
by h n	4
and reverse primers	4
by a novel	4
the cellular receptor	4
cell fusion in	4
fever and rash	4
of the international	4
e and a	4
of dengue virus	4
even though the	4
the first cohort	4
was the most	4
lpw lpw and	4
were further cultivated	4
to each well	4
of the negative	4
challenges for arbovirus	4
c virus infection	4
the ns protein	4
the patients were	4
neonatal scid mice	4
by blastn analysis	4
from the clinical	4
the ability to	4
the avian influenza	4
highly pathogenic h	4
retrieved from the	4
for more than	4
has been detected	4
were approved by	4
conjugated secondary antibody	4
the protective effects	4
receptor binding site	4
the united arab	4
in samples from	4
of the national	4
soon as possible	4
hepaciviruses and pegiviruses	4
infect eukaryotic organisms	4
emergence of these	4
as previously reported	4
a late stage	4
could be identified	4
for avian influenza	4
the availability of	4
in southern china	4
samples were also	4
nasopharyngeal samples of	4
role in viral	4
the nature and	4
of severe respiratory	4
obtained from all	4
was performed by	4
s and s	4
of liver injury	4
blood cell counts	4
samples were positive	4
divergent h n	4
blockade of c	4
the diversity of	4
of cynomolgus macaques	4
rna mini kit	4
the antibody response	4
potential role in	4
identified by hts	4
pneumonia in china	4
the results indicated	4
lung injury induced	4
fused to the	4
with enterovirus d	4
a cluster of	4
pdcov n gene	4
committee of the	4
in the cytoplasm	4
pneumoniae carriage increased	4
coronaviruses in the	4
at least three	4
of ali induced	4
an increase in	4
has been shown	4
samples positive for	4
torque teno virus	4
a decrease in	4
may result in	4
of influenza viruses	4
united arab emirates	4
in icu patients	4
licensed under a	4
viral titers in	4
qiaamp viral rna	4
was performed with	4
infected with a	4
emerging microbes and	4
of antibodies against	4
neutralizing antibodies in	4
structural basis of	4
from the survival	4
respiratory tract disease	4
committee on taxonomy	4
the above results	4
directly interact with	4
is required for	4
respiratory viral panel	4
is licensed under	4
a novel avian	4
three patients with	4
as indicated by	4
strategies and challenges	4
with sterile pbs	4
patients admitted to	4
to encode a	4
of the host	4
of the data	4
and light chain	4
are required to	4
children with respiratory	4
the intensive care	4
to the same	4
for wt or	4
be used for	4
antibody targeting the	4
were then incubated	4
and so on	4
isolation of wnv	4
as a control	4
with pdcov at	4
funders had no	4
therapeutic potential of	4
membrane attack complex	4
zikv and denv	4
were confirmed by	4
its emergence in	4
of m protein	4
on day after	4
two weeks after	4
preparation of the	4
days after the	4
the patients whose	4
to years old	4
have been found	4
course of mers	4
derived from a	4
pneumonia outbreak associated	4
with gout symptom	4
the appearance of	4
severe respiratory disease	4
of the complete	4
the potential of	4
in the specimens	4
were observed for	4
it is also	4
in the sera	4
zikv isolated from	4
well as a	4
for transmission of	4
a series of	4
and identification of	4
rna extracted from	4
pathogenic h n	4
a copy of	4
clinical features and	4
causative agent for	4
and lower respiratory	4
cultivated without trypsin	4
were tested positive	4
human coronavirus infections	4
were incubated with	4
ns a protein	4
imported case of	4
new insights into	4
infected with sars	4
trends in emerging	4
associated with enterovirus	4
interaction between the	4
epidemiology and clinical	4
of the polymorphic	4
is based on	4
a pneumonia outbreak	4
wt was set	4
materials and methods	4
positive for zikv	4
of alphacoronavirus and	4
b and orf	4
microbes and infections	4
was capable of	4
emergence of novel	4
have a role	4
entry of mers	4
transmission of prv	4
hepatitis b patients	4
n protein was	4
humans and other	4
nasopharyngeal specimens are	4
implications for the	4
from humans to	4
h n antibodies	4
are presented as	4
also detected in	4
excluded based on	4
are necessary to	4
we thank dr	4
samples from patients	4
indicate that the	4
origin influenza a	4
in bronchoalveolar lavage	4
pooled liver and	4
the diagnosis and	4
healthy control group	4
of the mice	4
deposited in genbank	4
that the presence	4
isolation of the	4
our study were	4
flow cytometry and	4
the results of	4
for the treatment	4
antibody against zika	4
risk of human	4
the immune system	4
virus infections among	4
suggest that c	4
in the icu	4
with the exception	4
reverse transcription pcr	4
and weight loss	4
viruses by dfa	4
as soon as	4
viral diversity in	4
implicated in the	4
coronavirus m protein	4
identified in this	4
the deutsche forschungsgemeinschaft	4
probable bat origin	4
in study design	4
in infected patients	4
the mice in	4
the exception of	4
viral s protein	4
detection of the	4
it difficult to	4
by western blot	4
syndrome coronavirus in	4
of these studies	4
cells infected with	4
enterovirus d infection	4
then incubated with	4
anal swab samples	4
fecal samples were	4
spike protein of	4
were present in	4
poultry workers in	4
dromedary wnv genome	4
in the detection	4
may play a	4
a highly pathogenic	4
patients who were	4
the coronavirus study	4
we thank the	4
vaccination against ipd	4
in vitro studies	4
complete genome sequences	4
global trends in	4
hku in respiratory	4
the investigation of	4
mice treated with	4
close contact with	4
hospitalized patients with	4
by the fc	4
constructed using the	4
h n were	4
as mentioned above	4
in previous studies	4
acute flaccid paralysis	4
to reduce the	4
similar to those	4
to other wnvs	4
caused by a	4
a higher viral	4
of viral n	4
of the middle	4
the two strains	4
residues in dpp	4
derived from the	4
were the most	4
of the emerging	4
its inhibitory effect	4
mabs b and	4
human metapneumovirus infection	4
as the template	4
the form of	4
from april to	4
have been described	4
the concentration of	4
zikv can be	4
late stage of	4
th and th	4
results of the	4
of clinical signs	4
to compare the	4
chronic obstructive pulmonary	4
a novel group	4
higher viral load	4
acid sequences of	4
the level of	4
of probable bat	4
first part of	4
and their potential	4
that m e	4
therapeutic efficacy of	4
in children and	4
the mfi value	4
centre cohort of	4
of dengue fever	4
human parainfluenza virus	4
the proportion of	4
genome sequences of	4
that can be	4
the incidence of	4
culture medium was	4
the most common	4
measures such as	4
in the pei	4
as compared to	4
before and during	4
of trypsin on	4
may be the	4
like h n	4
innate and adaptive	4
of the goose	4
effects of p	4
confocal laser scanning	4
progressive multifocal leukoencephalopathy	4
treated with mab	4
coronavirus s protein	4
confirmed that the	4
vast majority of	4
mortality rate of	4
with previous reports	4
among french pilgrims	4
the route of	4
copy of this	4
and na genes	4
the result of	4
by multiplex pcr	4
k e or	4
of patients whose	4
known viral respiratory	4
supernatants were collected	4
using first round	4
to view a	4
a mouse model	4
assigned to viruses	4
have shown that	4
foundation of china	4
during the first	4
luciferase reporter assay	4
african green monkeys	4
first affiliated hospital	4
vaccine based on	4
were maintained in	4
and during the	4
at a late	4
in mainland china	4
patients with mild	4
increase virus replication	4
can be detected	4
prior to admission	4
we report the	4
virus rna in	4
data indicate that	4
detection and genetic	4
clinical signs of	4
the in vitro	4
as determined by	4
strains isolated from	4
ics formed with	4
emergence of enterovirus	4
virus in china	4
intranasal application of	4
account for the	4
and dengue virus	4
multiple sequence alignment	4
was admitted to	4
host range of	4
in cases of	4
as in the	4
the acquisition of	4
were considered to	4
formation of ics	4
antiviral response by	4
and anal swabs	4
and severe acute	4
protein of the	4
have been shown	4
was funded by	4
after the initial	4
could be detected	4
infection in llc	4
all the children	4
lpw and second	4
avian nephritis virus	4
of the art	4
s protein of	4
of genetically diverse	4
be related to	4
sequences were generated	4
protection against influenza	4
with respiratory symptoms	4
was present in	4
the materials and	4
poultry drinking water	4
was transferred to	4
and n genes	4
cases in wuhan	4
to be developed	4
was quantified by	4
reported in different	4
lr region of	4
the saliva samples	4
influenza a rna	4
infected with zikv	4
mechanism by which	4
further cultivated without	4
cell entry of	4
of the present	4
infected mdck cells	4
virus replication and	4
increased circulation of	4
with severe acute	4
injury induced by	4
the putative ns	4
be positive for	4
on taxonomy of	4
not result in	4
the first affiliated	4
creative commons attribution	4
of the mabs	4
to experimental infection	4
surface expression of	4
transmission dynamics in	4
with a new	4
of more than	4
of a family	4
coronavirus of probable	4
grants from the	4
the influenza a	4
the lr region	4
virus isolated from	4
the first part	4
included in this	4
human respiratory disease	4
clustered with the	4
ncov spike protein	4
in the form	4
genbank accession numbers	4
and methods section	4
related to hepatitis	4
human respiratory syncytial	4
type i ifn	4
information on the	4
by dfa or	4
of the cases	4
followed by cycles	4
a combination of	4
mortem analysis of	4
of at least	4
a public health	4
anal swabs and	4
the isolated virus	4
neutralizing antibodies isolated	4
in these patients	4
associated with fatal	4
not detected in	4
was significantly higher	4
the potential for	4
arbovirus control g	4
were seeded in	4
in an fc	4
that infect eukaryotic	4
emergence of multiple	3
patients with influenza	3
is important to	3
immunosuppressive activity of	3
for at least	3
were analyzed using	3
collected samples from	3
v and l	3
the mn chimera	3
there are no	3
of binding to	3
closely related wnv	3
during acute infection	3
s dpp interaction	3
are able to	3
b cells of	3
n strains from	3
of novel hepaciviruses	3
that trypsin significantly	3
visceral gout in	3
recognized by the	3
and can be	3
differed from those	3
and the usa	3
the fc fragment	3
sparrow cov strain	3
betacoronavirus and avian	3
we observed that	3
in this regard	3
and incubated with	3
sichuan s from	3
they had been	3
detection of zika	3
between wt and	3
were used to	3
testing showed that	3
the national health	3
dpp wt was	3
technology major project	3
approach identifies a	3
of chicken astrovirus	3
the effects of	3
was dependent on	3
sample on day	3
independent positive mutual	3
spillover of prvs	3
the protective efficacy	3
and evidence of	3
effects by antiviral	3
pdcov and sparrow	3
in wuhan outbreak	3
of respiratory tract	3
on the basis	3
confirmed cases of	3
and blood samples	3
immunized with empty	3
tested negative by	3
the fourth passage	3
public health capacity	3
within days of	3
genome sequencing and	3
and characteristics of	3
macrophages and neutrophils	3
the endemic hcovs	3
phylogenetic analyses of	3
the outbreak in	3
modulation of antiviral	3
were cloned into	3
mice injected with	3
a cause of	3
a novel astrovirus	3
ground glass opacity	3
of antiviral cytokines	3
the state of	3
at rt for	3
glycoproteins e and	3
temporary left ventricular	3
both cell types	3
transport medium for	3
of the detection	3
has spread to	3
in many cases	3
independently associated with	3
wide range of	3
the v g	3
lung viral titer	3
different epitopes on	3
health diagnostic laboratories	3
strains associated with	3
in the virus	3
of amino acids	3
two individual pneumonia	3
of avian h	3
between the viral	3
to determine whether	3
that did not	3
pandemic influenza virus	3
the influence of	3
with the potential	3
after the onset	3
cloacal swabs were	3
incremental benefit of	3
in cell lysates	3
of proinflammatory cytokines	3
that such viruses	3
the ace receptor	3
the rate of	3
for these viruses	3
also susceptible to	3
saliva and urine	3
confirmed the presence	3
for h in	3
distinct from the	3
innate immune system	3
were tested by	3
emergence in the	3
chronic hepatitis c	3
coronavirus in dromedary	3
group immunized three	3
the minelute pcr	3
activation of the	3
we also demonstrated	3
on the same	3
to be reported	3
disposable handkerchiefs was	3
by antiviral mabs	3
the relatively high	3
our knowledge of	3
the pellet was	3
but not nf	3
of hnigga against	3
against prv m	3
the generation of	3
to zikv infection	3
trachea lung samples	3
from dromedaries in	3
sequencing was performed	3
cov s dpp	3
the guidelines for	3
avian coronaviruses as	3
with respiratory failure	3
floating and necrotic	3
factors for mortality	3
samples from the	3
or in the	3
outbreak in the	3
hh patients with	3
was noted in	3
astrovirus as a	3
negative results in	3
is critical to	3
by a grant	3
a single orf	3
into target cells	3
characterized in this	3
and propagation of	3
necrotic cells were	3
activities of these	3
the antigenic drift	3
the advantage of	3
the humoral and	3
take into account	3
evidence for the	3
alignment of the	3
were also observed	3
neutralization of sars	3
of viral infection	3
salt bridge with	3
history of chronic	3
virus m gene	3
in of samples	3
group of respiratory	3
antigen detection assay	3
infectious disease emergence	3
expression vector for	3
coronavirus in wuhan	3
central nervous system	3
the serum samples	3
lungs of mice	3
source of alphacoronavirus	3
for additional h	3
of children with	3
distribution of ace	3
genetics analysis version	3
infection in children	3
patients with avian	3
pan american health	3
database in genbank	3
goose chn sd	3
histologic examination revealed	3
and clinical management	3
the neutralization assay	3
zika virus zika	3
mers coronavirus in	3
viruses were detected	3
of an outbreak	3
transmission of infectious	3
national science and	3
the ns gene	3
outbreak of middle	3
and evaluation of	3
the virus lifecycle	3
for pathogenesis and	3
potential risk of	3
protein with traf	3
effects of trypsin	3
by immune complex	3
general medical ward	3
release of histones	3
the epidemiology of	3
a type i	3
with influenza virus	3
the secondary antibody	3
the basis of	3
clinical signs during	3
first reported in	3
the receptor binding	3
protein by trypsin	3
pathogenic viral infections	3
were selected for	3
studies on the	3
out using the	3
patients should be	3
the introduction of	3
transmembrane domains of	3
detection and phylogenetic	3
between family members	3
genome characterization of	3
on the complete	3
source of gammacoronavirus	3
which may have	3
of the luminex	3
of the strains	3
their potential role	3
binding domain complexed	3
activities in the	3
to infect humans	3
in their npa	3
cov strains from	3
the largest single	3
promoter activity was	3
that they were	3
was observed for	3
protective effects of	3
maximum likelihood method	3
to minimize the	3
and characterisation of	3
were analysed using	3
accession numbers mh	3
lung and kidney	3
with hbsag anti	3
apn cells were	3
and technology major	3
but also to	3
infection than st	3
and infected cells	3
cells were observed	3
such as tnf	3
multiplex reverse transcription	3
compared to pre	3
antibodies were purchased	3
and then the	3
the epidemic season	3
it is difficult	3
of deltacoronavirus in	3
of the antibodies	3
viral propagation and	3
zoonotic betacoronavirus causing	3
a potential therapeutic	3
several studies have	3
a family cluster	3
to the human	3
pcr based on	3
human whole blood	3
but not with	3
informed consent was	3
robust immunocompetent small	3
id and pact	3
of the irf	3
the forward and	3
underlying risk factors	3
the mice were	3
receptor for pdcov	3
influenza virus isolated	3
is due to	3
used in the	3
and necrotic cells	3
isu and isu	3
concentration of viral	3
were constructed using	3
vaccines and antiviral	3
target for developing	3
low levels of	3
rate of detection	3
the stimulation of	3
combined data of	3
de novo software	3
pros and cons	3
pathogenic coronavirus isolated	3
e immunized groups	3
as severe acute	3
two different mers	3
written informed consent	3
clinical microbiology laboratory	3
hbv ics to	3
to the novel	3
added to each	3
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after the first	3
denv ediii protein	3
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c a also	3
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the virus to	3
a virus h	3
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respiratory viruses of	3
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isolated in other	3
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patients who had	3