bigram

This is a table of type bigram and their frequencies. Use it to search & browse the list to learn more about your study carrel.

bigram	frequency
intensive care	795
mechanical ventilation	520
acute respiratory	479
critically ill	406
care unit	397
respiratory distress	355
septic shock	350
distress syndrome	313
ill patients	305
respiratory failure	243
ethics regulations	238
icu admission	231
patients admitted	207
risk factors	187
lung injury	170
icu stay	139
mortality rate	136
prone positioning	131
multivariate analysis	131
additional file	130
hospital mortality	130
cardiac arrest	123
two groups	123
pao fio	119
retrospective study	116
sofa score	115
ards patients	115
severe acute	107
care units	107
organ failure	105
severe ards	105
observational study	105
replacement therapy	103
renal replacement	103
icu patients	100
study period	98
mechanically ventilated	98
tidal volume	96
university hospital	94
mean age	92
membrane oxygenation	92
ml kg	91
factors associated	90
extracorporeal membrane	88
day mortality	88
critical care	86
prospective study	85
arterial pressure	85
adult patients	84
airway pressure	82
kidney injury	80
associated pneumonia	79
significantly higher	79
expiratory pressure	79
respiratory syndrome	78
invasive ventilation	76
antibiotic therapy	76
independently associated	76
saps ii	76
patients received	74
driving pressure	74
acute kidney	73
control group	73
patients receiving	70
icu mortality	70
ventilated patients	69
univariate analysis	68
pulmonary vascular	68
positive end	68
invasive mechanical	68
novel coronavirus	67
blood flow	67
included patients	66
acute lung	65
cohort study	65
systematic review	63
median age	62
cardiogenic shock	61
ecmo team	60
mg kg	60
respiratory tract	60
logistic regression	60
among patients	59
acquired pneumonia	59
patients treated	59
prone position	58
randomized controlled	58
clinical outcomes	58
risk factor	57
controlled trial	57
brain injury	56
significant difference	56
international congresses	54
spontaneous breathing	53
patients without	53
patients hospitalized	53
fio ratio	53
respiratory rate	52
high risk	52
years old	52
present study	51
sex ratio	50
hospital stay	49
lung volume	49
respiratory support	49
first days	49
nosocomial infections	49
respiratory mechanics	49
ann intensive	49
extradiaphragmatic inspiratory	48
doc id	47
care doi	47
poor outcome	47
severe sepsis	47
prognostic factors	47
heart rate	47
clinical trial	47
cord uid	47
clinical practice	46
regional strain	46
renal failure	46
significantly associated	46
blood pressure	46
pulmonary edema	45
pulmonary disease	45
copd patients	45
noninvasive ventilation	45
cardiac output	45
coronavirus disease	44
central venous	44
east respiratory	44
middle east	44
interquartile range	44
one patient	43
fluid balance	43
respiratory system	43
chronic obstructive	43
medical icu	43
performed using	42
high mortality	42
shock patients	42
obstructive pulmonary	42
flow nasal	41
oxygen therapy	41
least one	41
statistical analysis	41
plateau pressure	41
syndrome coronavirus	41
severe covid	41
organ dysfunction	41
body weight	41
critical illness	40
mortality rates	40
right ventricular	40
vascular resistance	40
pressure support	40
primary outcome	39
fluid administration	39
health care	39
informed consent	39
pediatric intensive	39
arterial blood	39
patients included	39
lung recruitment	38
infected patients	38
family members	38
consecutive patients	38
confidence interval	38
predictive factors	38
pulmonary arterial	38
higher mortality	37
nature remains	37
patients requiring	37
institutional affiliations	37
remains neutral	37
icu discharge	37
two patients	37
springer nature	37
jurisdictional claims	37
muscle activity	37
significant increase	37
cmv reactivation	37
fluid responsiveness	37
lung water	37
emergency department	37
study conducted	37
published maps	37
clinical characteristics	37
icu length	36
hospitalized patients	36
year period	36
increased mortality	36
authors read	36
protective ventilation	35
final manuscript	35
statistically significant	35
nasal cannula	35
adverse events	35
convalescent plasma	35
ii score	34
care medicine	34
nitric oxide	34
traumatic brain	34
lower respiratory	34
significantly lower	34
prospective observational	34
independent risk	34
failure assessment	34
respiratory virus	33
fluid resuscitation	33
public health	33
immunocompromised patients	33
acute physiology	33
tracheal intubation	33
longer duration	33
vps dsi	33
clinical trials	32
fluid therapy	32
icu beds	32
apache ii	32
inspiratory muscles	32
mean arterial	32
life support	32
clinical features	32
current study	32
note springer	32
bal fluid	32
pilot study	32
respiratory viruses	32
gas exchange	32
carbon dioxide	31
increased risk	31
support scientific	31
cardiac surgery	31
predictive value	31
odds ratio	31
berlin definition	31
scientific studies	31
research support	31
hypoxemic respiratory	30
niv failure	30
previous studies	30
kidney disease	30
exclusion criteria	30
randomized clinical	30
intubated patients	30
leading cause	30
pseudomonas aeruginosa	30
elderly patients	29
septic patients	29
neurological outcome	29
study including	29
i ratio	29
average age	29
team group	29
one hundred	29
simplified acute	29
pulmonary embolism	29
tidal volumes	29
significantly different	29
heart failure	29
long term	29
diaphragm dysfunction	29
study aimed	28
partial pressure	28
acute hypoxemic	28
sequential organ	28
ventilator settings	28
serum creatinine	28
ng ml	28
antibiotic treatment	28
cardiac index	28
poor prognosis	28
retrospective analysis	28
pulmonary hypertension	28
significant differences	28
medical intensive	27
multiple organ	27
dead space	27
inflammatory response	27
peep cmh	27
ventilatory support	27
influenza pneumonia	27
poorly recruitable	27
pk pd	27
endotracheal tube	27
authors declare	27
blood gas	27
prospective cohort	27
four patients	27
induced lung	27
release phase	27
retrospective cohort	27
staphylococcus aureus	27
hospital length	26
extubation failure	26
center study	26
compared using	26
body mass	26
severe pjp	26
noninfluenza group	26
data collection	26
nosocomial infection	26
median duration	25
space fraction	25
regression model	25
pneumocystis jirovecii	25
three patients	25
ethics committee	25
acute exacerbation	25
acute renal	25
extravascular lung	25
mers patients	25
patients undergoing	25
cirrhotic patients	25
study included	25
higher risk	25
within days	25
mass index	25
esophageal pressure	25
fluid management	24
shock index	24
mcg ml	24
lymphocyte count	24
bronchoalveolar lavage	24
burn patients	24
cancer patients	24
circulatory failure	24
primary endpoint	24
bacterial infection	24
clinical presentation	24
human metapneumovirus	24
pulmonary artery	24
france correspondence	24
reactive protein	24
competing interests	24
co removal	24
collected data	23
patients presenting	23
monocentric study	23
respiratory drive	23
mean duration	23
arterial ph	23
myocardial infarction	23
nasogastric tube	23
enteral nutrition	23
computed tomography	23
polymerase chain	23
rescue therapy	23
randomized trial	23
liver transplantation	23
left ventricular	23
chronic respiratory	23
ct scan	23
hoc analysis	23
pressure release	23
severe respiratory	23
supine position	23
healthcare workers	23
release ventilation	23
continuous variables	23
severe influenza	23
physiology score	23
chain reaction	23
blood gases	23
required mechanical	22
severe hypoxemia	22
five patients	22
lactate levels	22
prognostic value	22
regression analysis	22
recruitable patients	22
healthy subjects	22
patients required	22
chest wall	22
ngt insertion	22
infection prevention	22
month period	22
severity scores	22
post hoc	22
clinical signs	22
six patients	22
side effects	22
intracranial hypertension	22
including patients	22
preliminary cohort	22
success rate	22
status epilepticus	22
infectious complications	22
inclusion criteria	22
endotracheal intubation	21
pulmonary dead	21
standard care	21
per year	21
low tidal	21
chronic kidney	21
hemodynamic instability	21
pandemic influenza	21
associated infection	21
expiratory flow	21
general anesthesia	21
highly recruitable	21
requiring mechanical	21
european society	21
sample size	21
first attempt	21
dynamic driving	21
median time	21
descriptive study	21
support ventilation	21
inspiratory muscle	21
age years	21
glasgow coma	20
trauma patients	20
exact test	20
ill children	20
adult respiratory	20
study showed	20
ischemic stroke	20
multidisciplinary team	20
aki stage	20
severe infections	20
fluid overload	20
antimicrobial therapy	20
mm hg	20
severity score	20
assessed using	20
patients aged	20
tract infections	20
data suggest	20
clinical data	20
inhaled nitric	20
jirovecii pneumonia	20
saudi arabia	19
results suggest	19
positive airway	19
ml min	19
data analysis	19
high morbidity	19
transpulmonary thermodilution	19
lung disease	19
infectious diseases	19
predicted body	19
prospectively collected	19
per day	19
pulmonary infection	19
deep sedation	19
blood cultures	19
weak recommendation	19
free days	19
inspired oxygen	19
pulmonary syndrome	19
blood culture	19
hemodynamic parameters	19
therapeutic management	19
patients presented	19
may lead	19
may result	19
tcav method	19
medical records	19
expert opinion	19
extracorporeal life	19
eight patients	18
analyzed using	18
extracorporeal co	18
single center	18
respiratory effort	18
peep level	18
supplementary information	18
medical history	18
microcirculatory blood	18
patients died	18
corresponding author	18
overall mortality	18
study performed	18
frequency oscillatory	18
significantly increased	18
significant decrease	18
defined according	18
system compliance	18
patients infected	18
early intubation	18
direct examination	18
respiratory infection	18
viral infection	18
acinetobacter baumannii	18
hospital cardiac	18
information accompanies	18
support outside	18
high flow	18
minute ventilation	18
validation cohort	18
oscillatory ventilation	18
health problem	18
kg min	18
flow oxygen	18
even though	17
continuous renal	17
seven patients	17
roc curve	17
average length	17
alveolar recruitment	17
associated ards	17
negative patients	17
optimal mpaw	17
coronavirus pneumonia	17
study population	17
median length	17
dynamic hyperinflation	17
weaning process	17
institutional review	17
reasonable request	17
impedance tomography	17
care workers	17
multidisciplinary approach	17
identify factors	17
organ support	17
unfavorable outcome	17
infection control	17
tube insertion	17
patient characteristics	17
airway closure	17
vasoactive drugs	17
hazard ratio	17
sofa scores	17
creatinine clearance	17
patients developed	17
electrical activity	17
virus infection	17
teaching hospital	17
right ventricle	17
icu los	17
infectious disease	17
parenteral nutrition	17
discharged alive	17
liver failure	17
data regarding	16
retrospective observational	16
multicenter study	16
cd lymphocyte	16
acute circulatory	16
baseline characteristics	16
lactate level	16
review board	16
onset vap	16
negative bacilli	16
hospital discharge	16
alae nasi	16
stem cell	16
vascular dysfunction	16
klebsiella pneumoniae	16
results patients	16
clinical course	16
prospective multicenter	16
ecmo patients	16
data acquisition	16
international guidelines	16
incidence rate	16
considered significant	16
nine patients	16
hepatic encephalopathy	16
lung tissue	16
sort maneuver	16
aspiration pneumonia	16
early stage	16
patients underwent	16
shockable rhythm	16
volume expansion	16
oxygen saturation	16
derivation cohort	16
control study	16
ecmo group	16
weaning failure	16
practice guidelines	16
ventilation distribution	15
main objective	15
hfnc failure	15
hsv cmv	15
previously described	15
vasopressor support	15
cranial trauma	15
sepsis campaign	15
group versus	15
cov infection	15
medical staff	15
burned patients	15
respiratory muscles	15
median sofa	15
standard deviation	15
cor pulmonale	15
hand hygiene	15
cox model	15
groups according	15
pleural effusion	15
patients intubated	15
medical care	15
missing data	15
clinical outcome	15
surviving sepsis	15
icu alos	15
peep levels	15
blood samples	15
last years	15
intellectual content	15
electrical impedance	15
acute pancreatitis	15
per patient	15
hypercapnic respiratory	15
rank test	15
ten patients	15
primary objective	15
respiratory acidosis	14
observational cohort	14
high rate	14
chest tube	14
neuromuscular blockers	14
significant association	14
may help	14
epidemiological characteristics	14
organ donation	14
ventilation strategy	14
icu team	14
lung recruitability	14
open access	14
adverse effects	14
prognostic impact	14
diastolic shock	14
demographic data	14
healthcare use	14
unfractionated heparin	14
commonly used	14
inspiratory effort	14
influenza infection	14
lung regions	14
receiver operating	14
failure requiring	14
ml cmh	14
venous catheter	14
recruited lung	14
recent studies	14
independent predictors	14
whole population	14
analysis showed	14
influenza patients	14
acquired weakness	14
flow rate	14
respiratory samples	14
metabolic acidosis	14
relative risk	14
continuous positive	14
inspiratory time	14
interstitial lung	14
acinetobacter baumanii	14
spontaneously breathing	14
alveolar damage	14
early phase	14
ill adults	14
study shows	14
negative predictive	14
ecmo support	14
time spent	14
secondary outcomes	14
biological data	14
important intellectual	14
united states	14
herpesviridae reactivation	14
tissue perfusion	14
categorical variables	14
beneficial effect	13
lung ultrasound	13
transthoracic echocardiography	13
experts suggest	13
volume ventilation	13
randomized trials	13
systolic blood	13
immune system	13
del lili	13
secondary objectives	13
enteral feeding	13
systolic function	13
ventricular failure	13
lung strain	13
antibiotic prophylaxis	13
preliminary results	13
antibiotic prescription	13
slope fe	13
surgical intensive	13
glasgow score	13
datasets used	13
care med	13
hematological malignancies	13
study design	13
diabetic ketoacidosis	13
intravenous fluid	13
weaning protocol	13
fluid loading	13
controlled trials	13
health workers	13
hiv infection	13
factors independently	13
platelet count	13
survival rate	13
identify patients	13
may also	13
year survival	13
receiving respiratory	13
invasive aspergillosis	13
previously reported	13
emg peak	13
atrial fibrillation	13
regional lung	13
hematologic malignancies	13
assess whether	13
world health	13
clinical pulmonary	13
written informed	13
study protocol	13
cpis value	13
first day	13
cpap phase	13
lung protective	13
coronavirus infection	13
arterial oxygen	13
mers cases	13
urinary tract	13
refractory cardiac	13
gold standard	13
pulmonary oedema	13
severe patients	13
invasive fungal	13
acute poisoning	13
valle del	13
multivariate logistic	13
studies reported	13
hypoxic pulmonary	13
acute brain	13
patients experienced	13
respiratory infections	12
french icus	12
recruitment maneuver	12
urinary output	12
refractory cardiogenic	12
significantly reduced	12
diffuse alveolar	12
statistical analyses	12
induced changes	12
common cause	12
pulmonary manifestations	12
resistant bacteria	12
least days	12
determined using	12
abdominal surgery	12
positive predictive	12
clinical manifestations	12
icu teams	12
loading dose	12
end expiratory	12
sodium lactate	12
hsv reactivation	12
care department	12
arterial lactate	12
blood cell	12
linear mixed	12
following criteria	12
antibiotic susceptibility	12
injury severity	12
surface emg	12
blood volume	12
pulmonary vasoconstriction	12
mesenteric ischemia	12
rr adjustment	12
multidisciplinary ecmo	12
making process	12
bacterial pneumonia	12
inhibitory concentration	12
susceptibility testing	12
stroke volume	12
bed icu	12
renal function	12
lopinavir ritonavir	12
independent predictor	12
patients suffering	12
pneumocystis carinii	12
urine output	12
operating room	12
positive fluid	12
average time	12
bed medical	12
moderate ards	12
quantitative variables	12
requiring icu	12
solid tumors	12
fluid challenge	12
lower tidal	12
high peep	12
transplant recipients	12
scatter plot	12
worse outcomes	12
herpes simplex	12
health organization	12
failure rate	12
ill covid	12
prospective studies	12
blood products	12
brain death	12
working group	12
ali ards	12
intubated early	12
hypoxemic patients	12
myocardial dysfunction	12
peak airway	12
prognostic factor	12
prolonged mechanical	12
days following	12
influenza virus	12
lower mortality	12
steady state	12
higher rate	12
sort group	12
breathing trial	12
related ards	12
surgical patients	12
vascular tone	12
mechanical ventilator	12
blood transfusion	12
infection score	12
nasal oxygen	12
space ventilation	12
patients still	12
previous study	12
associated events	12
nervous system	12
pg ml	12
plot depicting	12
secondary infection	11
ibn rochd	11
thymosin alpha	11
diastolic dysfunction	11
cardiopulmonary resuscitation	11
simplex virus	11
acute cor	11
disease severity	11
multivariate regression	11
poor outcomes	11
task force	11
clinical studies	11
coma scale	11
icu staff	11
study suggests	11
see additional	11
male gender	11
prone ventilation	11
ncip patients	11
multicenter cohort	11
median delay	11
immunodeficiency virus	11
early sepsis	11
surgical site	11
carbon monoxide	11
lst limitation	11
chronic health	11
mait cells	11
survival analysis	11
financial support	11
infected pneumonia	11
balanced solutions	11
therapeutic hypothermia	11
heart disease	11
children aged	11
neutropenic patients	11
diagnostic criteria	11
severe pneumonia	11
higher peep	11
poor neurological	11
pulmonary aspergillosis	11
independent factors	11
significant correlation	11
solid organ	11
large number	11
french intensive	11
endothelial cells	11
statistical significance	11
protective effect	11
hospital admission	11
nosocomial pneumonia	11
diastolic arterial	11
artery catheter	11
bacterial resistance	11
carinii pneumonia	11
observational studies	11
pd target	11
refractory hypoxemia	11
pulmonary blood	11
respiratory variations	11
volumetric strain	11
clinically relevant	11
high level	11
successful insertion	11
lung collapse	11
first pass	11
early diagnosis	11
center effect	11
much higher	11
fresenius medical	11
tract infection	11
children admitted	11
continuous infusion	11
ventilator associated	11
first study	11
immune response	11
acquired infections	11
associated tracheobronchitis	11
acute phase	11
patients discharged	11
bacterial coinfection	11
clinical examination	11
viral pneumonia	11
lumbar puncture	11
secondary objective	11
suspected infection	11
acute pulmonary	11
transpulmonary pressure	11
isolated bacteria	11
human immunodeficiency	11
critical revision	11
evaluated using	11
local signs	11
linear regression	11
opportunistic infections	11
fungal infection	11
positive patients	11
systemic inflammatory	11
underlying disease	11
receiving prone	11
main causes	11
endotracheal aspirate	10
main reason	10
oxygen fraction	10
demographic characteristics	10
early acute	10
flow curve	10
standard oxygen	10
limited number	10
delta pco	10
intubation rate	10
ventricular dysfunction	10
patients within	10
prospective randomized	10
study group	10
vital signs	10
pulmonary fibrosis	10
major adverse	10
widely used	10
end point	10
primary end	10
lung cancer	10
high levels	10
hemoglobin level	10
severe traumatic	10
resuscitation department	10
resuscitation fluids	10
disk diffusion	10
icu bed	10
cell count	10
fr annals	10
early use	10
health evaluation	10
patient outcomes	10
high dose	10
personal fees	10
patients diagnosed	10
acute mesenteric	10
dosing regimens	10
decompressive craniectomy	10
year mortality	10
antiviral therapy	10
several studies	10
per ventilator	10
flow distribution	10
mv duration	10
circulatory shock	10
respiratory parameters	10
thirty patients	10
lavage fluid	10
igs ii	10
viral co	10
endothelial dysfunction	10
ventilation strategies	10
dsi values	10
venous extracorporeal	10
venous blood	10
access correspondence	10
case series	10
prospectively included	10
average duration	10
every patient	10
fio decreases	10
neuromuscular blocking	10
group compared	10
also collected	10
diffusion method	10
beneficial effects	10
respiratory depression	10
investigate whether	10
eligible patients	10
admitted patients	10
converting enzyme	10
positive culture	10
mean saps	10
atrial pressure	10
iv infection	10
phase i	10
good outcome	10
hd tgc	10
lung aeration	10
final version	10
pediatric ards	10
hiv patients	10
bloodstream infections	10
pneumonia severity	10
ami patients	10
rel rs	10
data collected	10
chest trauma	10
severe brain	10
first weeks	10
niv hfnc	10
gas exchanges	10
body temperature	10
dysfunction failure	10
sublingual microcirculation	10
coronary artery	10
considered statistically	10
general population	10
venous pressure	10
prior antibiotic	10
clinical study	10
cardiac function	10
head trauma	10
cytokine storm	10
clinical impact	10
ps level	10
cox regression	10
per minute	10
mental health	10
acute myocardial	10
expiratory time	10
open lung	10
ab vap	10
following icu	10
several limitations	10
increased significantly	10
oxygen consumption	10
mortality among	10
expiratory duration	10
com annals	10
group without	10
early identification	10
kdigo criteria	10
eadi peak	10
mortality risk	9
sweep gas	9
organ failures	9
mg dl	9
low flow	9
head injury	9
normally distributed	9
drug monitoring	9
transition period	9
plateau pressures	9
approval number	9
study confirms	9
dosage regimen	9
twelve patients	9
abdominal infections	9
plasma therapy	9
validation cohorts	9
systolic dysfunction	9
large prospective	9
fisher exact	9
rescue therapies	9
antimicrobial susceptibility	9
two methods	9
qsofa score	9
first episode	9
hemorrhagic shock	9
antiretroviral therapy	9
another hospital	9
high doses	9
endexpiratory pressure	9
cardiac dysfunction	9
alveolar lavage	9
ivc diameter	9
major cause	9
similar results	9
frequent complication	9
also associated	9
prolonged icu	9
male predominance	9
low peep	9
better survival	9
performance status	9
identify risk	9
favorable outcome	9
fungal infections	9
preventive measures	9
pneumocystis pneumonia	9
positive endexpiratory	9
pulmonary syndromes	9
clinical cure	9
determine whether	9
fluid creep	9
one third	9
predict fluid	9
clinical parameters	9
receiving invasive	9
delta nlr	9
term outcomes	9
retrospective nature	9
severe bronchiolitis	9
purulent discharge	9
chest radiograph	9
personal protective	9
rheumatoid arthritis	9
plasma exchange	9
patient died	9
main reasons	9
mechanical power	9
blood glucose	9
extracorporeal blood	9
chest radiography	9
one patients	9
induced pulmonary	9
muscle weakness	9
protocol group	9
renal impairment	9
qualitative variables	9
acute exacerbations	9
overall survival	9
term survival	9
lung units	9
without significant	9
icu survivors	9
strong association	9
median saps	9
care patients	9
patients compared	9
respiratory muscle	9
related organ	9
enrolled patients	9
patients ventilated	9
pulmonary infections	9
large cohort	9
may contribute	9
term mortality	9
directed therapy	9
coma score	9
functional residual	9
inflammatory myopathies	9
residual capacity	9
continuous veno	9
protective equipment	9
controlled mode	9
receiving mechanical	9
statistically different	9
chest physiotherapy	9
hospital charges	9
normal lung	9
charlson comorbidity	9
general hospital	9
square test	9
multicenter prospective	9
operating characteristic	9
good neurological	9
vascular cause	9
fluid bolus	9
underlying malignancy	9
difficult intubation	9
regional deformation	9
antisynthetase syndrome	9
lung damage	9
severe tbi	9
care resources	9
severe infection	9
regional ventilation	9
heart association	9
secondary infections	9
global strain	9
flow cytometry	9
severe mers	9
therapeutic drug	9
pulmonary haemodynamics	9
clinical research	9
severe cases	9
ventilatory settings	9
remains high	9
following data	9
treatment failure	9
healthy volunteers	9
related infections	9
respiratory viral	9
viral infections	9
multivariable logistic	9
oral care	9
specialized advice	9
left ventricle	9
viral documentation	9
monocentric retrospective	9
systemic inflammation	9
brain damage	9
igs score	9
among critically	9
immune responses	9
resistant strains	9
pulmonary circulation	9
breathing patients	9
mixed icu	9
common risk	8
patients will	8
icu respiratory	8
obese patients	8
passive leg	8
first admission	8
developed vap	8
associated aki	8
early start	8
icu management	8
patient management	8
leg raising	8
significantly longer	8
survival rates	8
ionized calcium	8
initial severity	8
acute coronary	8
tertiary care	8
study day	8
ulcerative colitis	8
hemodynamic monitoring	8
hemodynamic profile	8
predict mortality	8
patient without	8
significantly related	8
central nervous	8
significantly decreased	8
closely related	8
main outcome	8
normal saline	8
clinical evidence	8
selected patients	8
retrospectively studied	8
lung infection	8
recent study	8
first week	8
copd exacerbation	8
severe aki	8
median value	8
healthcare system	8
chronic liver	8
pressure rooms	8
factors related	8
inspiratory flow	8
improving global	8
site infection	8
groups regarding	8
shock population	8
regional volumetric	8
study reported	8
dioxide removal	8
hematological malignancy	8
severe community	8
month mortality	8
confounding factors	8
corticosteroid therapy	8
bone marrow	8
eeg reactivity	8
nutritional support	8
time points	8
early vap	8
time course	8
hospital center	8
small sample	8
patients older	8
prehospital setting	8
right heart	8
chronic heart	8
oxygen concentrator	8
opening pressure	8
ventilator support	8
author information	8
ecmo program	8
emergency room	8
host response	8
chu angers	8
blocking agents	8
citrate anticoagulation	8
glucocorticoid therapy	8
significantly improved	8
hypercapnic acidosis	8
full list	8
ventilation may	8
hemorrhagic stroke	8
global outcomes	8
invasive respiratory	8
fluid volume	8
well known	8
volumetric capnography	8
deeply sedated	8
twenty patients	8
generating procedures	8
fisher paykel	8
differentiate vat	8
score ii	8
tunisia correspondence	8
adverse drug	8
microbiological documentation	8
burn intensive	8
cardiogenic pulmonary	8
cell transplantation	8
ultraprotective ventilation	8
therapeutic strategies	8
simplified score	8
high respiratory	8
improve survival	8
drug administration	8
fio mmhg	8
bacterial meningitis	8
intervention group	8
dose tigecycline	8
feeding tube	8
antiviral drugs	8
lactate clearance	8
inspiratory pressure	8
randomised controlled	8
risk patients	8
mpaw step	8
spearman rho	8
continuous intravenous	8
required invasive	8
retrospective monocentric	8
diaphragm activity	8
chi square	8
older age	8
antimicrobial resistance	8
diagnostic accuracy	8
improved survival	8
confirmed cases	8
venous ecmo	8
small number	8
assessment score	8
high prevalence	8
results one	8
antiviral treatment	8
lung mechanics	8
days vs	8
postoperative infections	8
kg pbw	8
mpaw titration	8
previously published	8
peak pressure	8
respiratory disease	8
respiratory syncytial	8
remains controversial	8
measured using	8
case report	8
association study	8
patients showed	8
neuromuscular blockade	8
ventilation duration	8
patients whose	8
parasternal intercostals	8
line therapy	8
ill adult	8
high incidence	8
may explain	8
functional status	8
cytomegalovirus reactivation	8
health insurance	8
expiratory muscle	8
french law	8
secondary endpoints	8
roc curves	8
acute stroke	8
regression models	8
significant changes	8
baseline serum	8
systolic arterial	8
injured lung	8
ill patient	8
intravenous fluids	8
multicenter observational	8
mixed model	8
antiviral activity	8
identify variables	8
ventilation time	8
pass success	8
oxygenation parameters	8
rv failure	8
surgical icu	8
bacterial infections	8
clinical efficacy	8
incidence density	8
arrest related	8
rel gene	8
pjp diagnosis	8
missing baseline	8
whitney test	8
organ transplantation	8
berlin criteria	8
retrospective descriptive	8
vap diagnosis	8
intermediate care	8
red blood	8
american heart	8
stroke patients	8
antibiotic use	8
propensity score	8
future studies	8
injured lungs	8
community acquired	8
supportive care	8
therapeutic failure	8
inclusion period	8
target non	8
control practices	8
patients may	8
intracranial pressure	8
clinical decision	8
coronary intervention	8
one case	8
viral load	8
weaning criteria	8
related problems	8
using logistic	8
volume curve	8
minimum inhibitory	8
severe sars	8
study aims	8
rv dysfunction	8
important role	8
reduce mortality	8
recently reported	8
microvascular blood	8
controlled study	8
center retrospective	8
ill cancer	8
medical conditions	8
total peep	8
final diagnosis	8
individual patient	8
death occurred	8
liver cirrhosis	8
type i	8
invasive support	7
ventilation perfusion	7
streptococcus pneumoniae	7
ckd lps	7
testosterone levels	7
prognosis factors	7
vena cava	7
every min	7
decreasing peep	7
variables associated	7
mic values	7
early recognition	7
conventional ventilation	7
final model	7
surface area	7
decreased mortality	7
ards model	7
hemodynamic effects	7
advance directives	7
chest ct	7
vessels perfused	7
organ dysfunctions	7
high rates	7
diaphragmatic paralysis	7
persistent aki	7
ill cirrhotic	7
musical intervention	7
compartment syndrome	7
available data	7
patients group	7
wilcoxon rank	7
spss software	7
ards criteria	7
might allow	7
protective mechanical	7
prognostic significance	7
virus disease	7
drug intoxication	7
patients due	7
main comorbidities	7
confidence intervals	7
oxygen flow	7
care system	7
pulse pressure	7
therapy alone	7
oxygen delivery	7
thyrotropic insufficiency	7
pressure mmhg	7
macintosh laryngoscope	7
venoarterial extracorporeal	7
late vap	7
respiratory insufficiency	7
induced acute	7
serum albumin	7
ohca patients	7
aged years	7
requiring hospitalization	7
systolic shock	7
resuscitation room	7
ards mortality	7
selection bias	7
identified patients	7
ventilator weaning	7
ventilator acquired	7
identified using	7
national health	7
introduction acute	7
remaining patients	7
acute ph	7
internal medicine	7
sublingual mucosa	7
average hospital	7
higher incidence	7
perioperative fluid	7
traditional medicine	7
data concerning	7
traditional tidal	7
hydroxyethyl starch	7
retract system	7
hospital outbreak	7
airway pressures	7
attending physicians	7
pediatric trauma	7
influenza pandemic	7
excluded patients	7
ventilator circuit	7
related complications	7
first time	7
phase ii	7
kg day	7
ards according	7
intravascular coagulation	7
gas flow	7
results obtained	7
died within	7
percutaneous coronary	7
neurological recovery	7
inlet cannula	7
mpaw level	7
sniffing position	7
mottling score	7
icu acquired	7
first three	7
lv diastolic	7
french university	7
henri mondor	7
longer icu	7
early detection	7
standard criteria	7
care society	7
retrospectively reviewed	7
statistical power	7
tavem study	7
factors influencing	7
tissue infections	7
acutely injured	7
psychological consult	7
cov outbreak	7
diabetic patients	7
severe pediatric	7
developed ards	7
refractory shock	7
control ventilation	7
spontaneous ventilation	7
median icu	7
cardiac arrests	7
hemodynamic failure	7
minimal inhibitory	7
respiratory frequency	7
hematopoietic stem	7
lung edema	7
care group	7
tracheal secretions	7
may provide	7
overdistended regions	7
macrophage recruitment	7
prospective single	7
dynamic compliance	7
baumannii vap	7
performed according	7
blood lactate	7
diabetes mellitus	7
randomly assigned	7
segment elevation	7
syndrome acute	7
invasive procedures	7
also found	7
receive either	7
miserable outcome	7
two hospitals	7
practice guideline	7
inspiratory support	7
acinetobacter spp	7
ecmo duration	7
positive blood	7
invasively ventilated	7
increased morbidity	7
past medical	7
neurologic outcome	7
oxygenation strategy	7
dynamic strain	7
weaning induced	7
wide association	7
required icu	7
microbiological sampling	7
different levels	7
initial dose	7
study demonstrates	7
also performed	7
among icu	7
critical patients	7
ethical committee	7
arterial partial	7
negative pressure	7
attributable mortality	7
physiological dead	7
severely ill	7
ngt placement	7
placebo group	7
multicenter retrospective	7
attending physician	7
acute cdi	7
rsv patients	7
french icu	7
successful weaning	7
icu physicians	7
comatose patients	7
syncytial virus	7
secondary analysis	7
received ecmo	7
mainly related	7
frequently used	7
peep setting	7
infections due	7
first line	7
co production	7
xa activity	7
clinical variables	7
guidelines recommend	7
airway opening	7
producing gnb	7
still alive	7
tracheal aspirates	7
flow index	7
rv systolic	7
icu ventilators	7
describe organ	7
viscoelastic behavior	7
ecls implantation	7
may allow	7
vasopressor infusion	7
invasive pulmonary	7
pao mmhg	7
team approach	7
term prognosis	7
algeria correspondence	7
supplementary material	7
lung fibrosis	7
critical covid	7
preliminary study	7
adverse effect	7
retrospective single	7
acute asthma	7
subgroup analysis	7
severe disease	7
hour urine	7
acute pe	7
hmpv infection	7
first hour	7
potential therapeutic	7
cardiac failure	7
also recorded	7
pressure ventilation	7
observational prospective	7
microcirculatory dysfunction	7
emergency departments	7
mean length	7
multivariate cox	7
insertion site	7
patients enrolled	7
clinical findings	7
receiving nmba	7
resistance profile	7
neurological disorders	7
total bilirubin	7
already discharged	7
bacterial ecology	7
dsi ne	7
stenotrophomonas maltophilia	7
venous return	7
unit patients	7
developing countries	7
comorbid medical	7
retrospective review	7
gnb infection	7
umbilical vein	7
diaphragm thickness	7
peep start	7
induced ards	7
per point	7
sapsii score	7
met criteria	7
gas infection	7
patients supported	7
patients according	7
median interquartile	7
previous reports	7
extracorporeal carbon	7
lung biopsy	7
serum concentrations	7
less severe	7
oxygen mask	7
main etiologies	7
immune function	7
care protocol	7
clinical suspicion	7
bacterial clearance	7
spontaneous circulation	7
transient aki	7
multivariable analysis	7
palliative care	7
kg predicted	7
platelet counts	7
severe complication	7
iu ml	7
orotracheal intubation	7
several factors	7
whole group	7
three different	7
care syndrome	7
cytokine release	7
cerebrospinal fluid	7
sedative drugs	7
clavulanic acid	7
care setting	7
pneumonia caused	7
conventional methods	7
recently published	7
capillary leak	7
shock populations	7
control measures	7
clinical situations	7
higher icu	6
medical surgical	6
strongly related	6
lung safe	6
exhaled co	6
steroid therapy	6
ventilated children	6
inferior vena	6
experienced hfnc	6
disseminated intravascular	6
cardiac injury	6
new technique	6
postoperative complications	6
maternal mortality	6
target attainment	6
studies suggest	6
different methods	6
lille university	6
resistant staphylococcus	6
metapneumovirus infection	6
strongly correlated	6
two different	6
resistance index	6
different time	6
polymicrobial sepsis	6
multicenter randomized	6
larger cohort	6
va ecmo	6
dzp bup	6
positron emission	6
biomechanical analysis	6
respiratory variables	6
serum vancomycin	6
plasma levels	6
consensus conference	6
experimental study	6
adverse event	6
isotonic saline	6
paediatric intensive	6
patients carrying	6
adaptive ventilation	6
electronic medical	6
infection due	6
viral loads	6
specific population	6
recipients admitted	6
confirmed mers	6
controlled adaptive	6
severity index	6
cci patients	6
life threatening	6
ancillary study	6
dead patients	6
light sedation	6
sessions performed	6
drug resistant	6
cpis values	6
sixteen patients	6
icu admissions	6
lower rate	6
trial registration	6
per log	6
caring relationship	6
min group	6
cell disease	6
gastric content	6
severe hypoxia	6
ritonavir group	6
performance category	6
abdominal sepsis	6
analysis identified	6
factor associated	6
lymphopenic patients	6
bacterial culture	6
mean sofa	6
moderate hypokalemia	6
systolic pressure	6
saps score	6
may reduce	6
local sign	6
chinese traditional	6
day one	6
results highlight	6
china clinical	6
children treated	6
muscular pressure	6
baseline creatinine	6
total number	6
associated acute	6
refeeding hypophosphoremia	6
severity factors	6
effective treatment	6
evlw changes	6
systolic excursion	6
plasma concentration	6
vt ml	6
full access	6
oral nutrition	6
participating centers	6
ethics approval	6
convulsive status	6
may affect	6
day survivors	6
liver dysfunction	6
term outcome	6
urine samples	6
different clinical	6
predictive values	6
secondary outcome	6
diseases society	6
ddd dh	6
alveolar collapse	6
cumulative fluid	6
early mortality	6
ventilated icu	6
i error	6
study also	6
serum pct	6
severe ae	6
respiratory diseases	6
alveolitis profile	6
unidentified etiology	6
patients complicated	6
parenchymal tethering	6
major risk	6
cause mortality	6
unit mortality	6
traumatic intracranial	6
white blood	6
ejection fraction	6
ventilation settings	6
strong agreement	6
epinephrine group	6
threatening organ	6
positive pressure	6
days iqr	6
another study	6
years period	6
abdominal hypertension	6
preliminary data	6
ventilated critically	6
better understand	6
resistant pathogens	6
creatine kinase	6
tracheal aspirate	6
care hospital	6
ic patients	6
acquired peritonitis	6
evaluation ii	6
low vt	6
study patients	6
standard therapy	6
among non	6
significant morbidity	6
ventilatory parameters	6
sepsis patients	6
lung lesions	6
arterial oxygenation	6
hospital refractory	6
research committee	6
renal clearance	6
immunosuppressive drugs	6
female predominance	6
limb ischemia	6
year old	6
changes induced	6
creatinine level	6
studies showed	6
upper airway	6
intravenous infusion	6
infusion rate	6
also showed	6
influenza group	6
cardiopulmonary bypass	6
specialized journals	6
per group	6
arrest patients	6
regional anticoagulation	6
mainly due	6
may influence	6
internal jugular	6
machine learning	6
septic cardiomyopathy	6
severe trauma	6
fit testing	6
lung inflation	6
mdr bacteria	6
routine use	6
many patients	6
medical literature	6
underlying diseases	6
viral clearance	6
intrinsic peep	6
ionized calcemia	6
pregnant women	6
norepinephrine group	6
consensus definitions	6
group vs	6
icu capacity	6
arterial hypertension	6
intercostal muscles	6
occlusion pressure	6
rate variability	6
membrane thrombosis	6
included children	6
crs changes	6
intravascular volume	6
oxygen administration	6
mv weaning	6
mean value	6
sedated patients	6
main cause	6
empirical treatment	6
filter lifespan	6
lower risk	6
short term	6
mean total	6
confirmed covid	6
pp session	6
cmv group	6
immune cells	6
significant impact	6
dependent regions	6
mechanical breath	6
base deficit	6
chest pain	6
analytical study	6
two hundred	6
critical cases	6
safe study	6
median iqr	6
organ function	6
ecmo center	6
false positive	6
total costs	6
ebola virus	6
outcome measure	6
derecruited volume	6
international consensus	6
daily clinical	6
hospital staff	6
sectional study	6
dap values	6
allowed us	6
major public	6
mean airway	6
received mechanical	6
endothelial glycocalyx	6
dysfunction syndrome	6
predicting mortality	6
definite probable	6
trend toward	6
care facilities	6
support organization	6
improve patient	6
random effect	6
mixed effect	6
nucleic acid	6
intravenous immunoglobulins	6
frequent cause	6
hemodynamic tolerance	6
low level	6
common reason	6
cov patients	6
fluid cytology	6
icu survival	6
tissue hypoperfusion	6
fatality rate	6
saudi ministry	6
normal distribution	6
severe cap	6
wall elastance	6
ct images	6
short time	6
parasternal intercostal	6
symptomatic treatment	6
differ significantly	6
gram negative	6
interval ci	6
antimicrobial stewardship	6
well described	6
pressure transducer	6
decision making	6
requiring intensive	6
endothelial cell	6
severe head	6
fatal poisoning	6
vessel density	6
empiric antibiotic	6
immune suppression	6
lung homogeneity	6
altitude pulmonary	6
prevention program	6
clinical breakpoints	6
ei group	6
opposition rate	6
salbutamol nebulization	6
findings suggest	6
vital status	6
oxygen partial	6
protection des	6
vulnerable patients	6
negative fluid	6
medical charts	6
modified sofa	6
standard method	6
french hospitals	6
gene expression	6
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patients characteristics	6
medical resources	6
cardiovascular events	6
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cannula group	6
respiratory status	6
strain progression	6
bed availability	6
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recent years	6
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recumbent position	6
worse outcome	6
intubation procedure	6
withdrawal syndrome	6
non invasive	6
affiliations none	6
wide range	6
ecmo implementation	6
study date	6
biological parameters	6
cardiovascular dysfunction	6
major bleeding	6
associated factors	6
remains unknown	6
cox proportional	6
last decade	6
rbc transfusion	6
pain assessment	6
hospital ibn	6
venous hemofiltration	6
cd group	6
inflammatory conditions	6
venous catheterization	6
small vessels	6
cell transplant	6
viral treatment	6
trend towards	6
th percentile	6
conservative fluid	6
improve arterial	6
using univariate	6
base equilibrium	6
critical opening	6
hr values	6
validation study	6
methods retrospective	6
empirical antibiotic	6
calculated just	6
two independent	6
larger studies	6
ards severity	6
based indices	6
outcome scale	6
syndrome secondary	6
first draft	6
high probability	6
strong recommendation	6
icu healthcare	6
viral shedding	6
pulmonary microvascular	6
psychological disorders	6
systolic pulmonary	6
healthcare professionals	6
exact tests	6
strain maps	6
epidemiological profile	6
treated medically	6
delivery room	6
therapeutic interventions	6
accelerate pheno	6
peep titration	6
acute ischemic	6
diastolic pressure	6
without mv	6
fatal carbon	6
mean risk	6
requiring invasive	6
results show	6
epithelial cells	6
respiratory assistance	6
emission tomography	6
statistical difference	6
study clinical	6
negative impact	6
january st	6
lung protection	6
cell deficiency	6
regional hospital	6
vascular access	6
study found	6
tranexamic acid	6
nssh patients	6
may impact	6
qualitative data	6
microbiologically confirmed	6
using clinical	6
control patients	6
line treatment	6
glasgow outcome	6
minor allele	6
one icu	6
results among	6
vasopressor start	6
early stages	6
french society	6
artery bypass	6
thyroid storm	6
adults admitted	6
last decades	6
ards group	6
organ donor	6
using different	6
per cent	6
measured fio	6
radiological findings	6
similar findings	6
filter ionized	6
better understanding	6
may occur	6
least two	6
march th	6
support levels	6
surgical resuscitation	6
weight loss	6
using two	6
medical center	6
second part	6
cerebral performance	6
made using	6
dendritic cells	6
ineffective triggering	6
lps animals	6
significant improvement	6
sars patients	6
assistance publique	6
observational retrospective	5
endobronchial intubation	5
renal dysfunction	5
shock following	5
management strategies	5
patient care	5
peep decrease	5
microbiologically documented	5
functional outcome	5
initial lactate	5
oran hospital	5
initial treatment	5
ecmo insertion	5
proper use	5
congestive heart	5
severe illness	5
clinical use	5
lung volumes	5
effects related	5
recruitment pattern	5
icu specialized	5
remains challenging	5
vasopressor dose	5
serum concentration	5
gas analysis	5
lung compliance	5
icu nurses	5
absolute value	5
perfused vessel	5
nutric score	5
common practice	5
ventilatorassociated pneumonia	5
patient comfort	5
gastric tube	5
isolated microorganisms	5
antimicrobial treatment	5
cerebral edema	5
see table	5
three days	5
central line	5
rnapol autoantibodies	5
table shows	5
experimental models	5
female gender	5
phase duration	5
two main	5
dilution method	5
substantial contribution	5
severely burned	5
ards caused	5
predict outcome	5
hypoxic vasoconstriction	5
pancreatic surgery	5
likely due	5
positive expiratory	5
hospital setting	5
central catheter	5
diaphragm function	5
iu kg	5
ventilator days	5
spectrum antibiotics	5
new simplified	5
study assessing	5
may benefit	5
artificial ventilation	5
neurosurgical care	5
cell death	5
massive influx	5
samples taken	5
acquiring mers	5
time curve	5
including pneumonia	5
cicu stay	5
liquid chromatography	5
invasive method	5
jc sessions	5
ventricular afterload	5
hfnc oxygen	5
ventilation parameters	5
ino alone	5
therapeutic decisions	5
brief expiratory	5
independent prognostic	5
synthetase syndrome	5
early administration	5
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retrospectively included	5
imv ae	5
increased duration	5
concern patients	5
ventilation mode	5
ards complicating	5
also considered	5
medical file	5
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hospital anxiety	5
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adult icu	5
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sfm guidelines	5
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autonomic nervous	5
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frozen plasma	5
experimental studies	5
groups using	5
oxygen circuit	5
clinical criteria	5
also studied	5
psychological support	5
traumatic aki	5
skin samples	5
neck flexion	5
drug users	5
dead organ	5
testosterone gel	5
bl overdosing	5
statistical software	5
arterial extracorporeal	5
multiorgan failure	5
bypass graft	5
burn care	5
preload dependence	5
strain heterogeneity	5
also used	5
france full	5
lung pathology	5
european north	5
patients suffered	5
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children hospitalized	5
third international	5
many studies	5
healthcare team	5
non survivors	5
piriform sinus	5
therapeutic strategy	5
assist may	5
new treatments	5
confounding variables	5
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first cause	5
resistance rates	5
dioxide gap	5
insulin resistance	5
th day	5
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oussama jaoued	5
bed mixed	5
depression scale	5
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human beings	5
upper airways	5
second period	5
regional citrate	5
sepsis admitted	5
better outcome	5
crossover study	5
low molecular	5
nutrition support	5
specific treatment	5
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acute severity	5
vv ecmo	5
emergency resuscitation	5
well tolerated	5
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associated infections	5
experimental data	5
esbls producing	5
theoretical immediate	5
last follow	5
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patient admitted	5
burnout syndrome	5
immune dysfunction	5
clinical relevance	5
aki patients	5
hemolytic anemia	5
put forward	5
therapeutic targets	5
evaluate whether	5
inflammatory markers	5
french guidelines	5
hospital workers	5
difference regarding	5
elevated pulmonary	5
medical ethics	5
eighteen patients	5
acquired infection	5
experimental ards	5
pressure cmh	5
patients alive	5
predict poor	5
frequently identified	5
ventricular systolic	5
clinical evaluation	5
nosocomial enterococcus	5
two university	5
sustaining therapy	5
corporeal membrane	5
nmo attacks	5
intracranial hemorrhage	5
four groups	5
contralateral rotation	5
ventricular function	5
oxygen titration	5
lung stress	5
cerebral insults	5
hypnosis sessions	5
randomly allocated	5
trough concentration	5
traumatic cause	5
tertiary referral	5
showed significant	5
bal samples	5
median number	5
prognostic marker	5
calcium channel	5
arf revealing	5
taken together	5
common complication	5
high blood	5
multicentre study	5
malignancies admitted	5
aged less	5
ss patients	5
time reverse	5
frequent among	5
inflammatory state	5
breakpoints according	5
myocardial involvement	5
important part	5
severe dyspnea	5
progressively higher	5
complement activation	5
weaning success	5
aerosol delivery	5
cpc score	5
kg per	5
sensitivity analysis	5
five cases	5
venous thrombosis	5
require mechanical	5
plasma protein	5
worse sofa	5
mental status	5
general electric	5
community peritonitis	5
high volume	5
also similar	5
peep increases	5
also demonstrated	5
dialysis sessions	5
scls attacks	5
mechanisms involved	5
corrected age	5
liver disease	5
therapeutic limitation	5
sickle cell	5
massive transfusion	5
including ventilator	5
viral copathogen	5
ventilated lung	5
mechanical properties	5
mean apache	5
published data	5
hyperammonemic encephalopathy	5
probably due	5
strong ion	5
anoxic comatose	5
hemorrhagic complications	5
sepsis diagnosis	5
medical systems	5
initial antibiotic	5
underwent mechanical	5
nephrotoxic drugs	5
spectrum antiviral	5
modified rankin	5
north american	5
venous access	5
severe organ	5
visual analogic	5
multivariate model	5
target range	5
artery pressure	5
catheter related	5
appropriate antimicrobial	5
fluid removal	5
study groups	5
ten cases	5
submitted work	5
plasma concentrations	5
young children	5
one study	5
treatment initiation	5
study spread	5