%^*% $-^^;;tiS^. ^:ii "^k h^' ^'^^> &l^: -5!<, i^>' ~i t, aV''2^Y ■^■ W-f^'^ %^^ fci; . b h \ '9^- t 1 Vi INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Xlcansactions OF SECOND SESSION, HELD IN MELBOURNE, VICTORIA, JANUARY, 1889. PUBLISHED UNDER THE DIRECTION OF THE LITERARY COMMITTEE. LIBRARY OTTRE LOS AlWiELES COUNTY MEDICAL ASSOCIATION 634 SOUTH WEGTLAKE AVE, MELBOURNE: STILLWELL AND CO., PRINTERS, 195A COLLINS STREET. 1889. %' \^ /j.S^-tQl : ClUM ^ INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. SECOND SESSION. PATI^)N8. His Excellenx'y !Sik Hexky Brougham Loch, G.C.M.G., K.C.E., Governoi' of Victoi-ia. His Exckllency the Kkuit Honorable Lord Carrington, G.C.M.U., Governor of New 8outli Wales. His Excellency Sir AV^illiam F. DrumiMond Jervois, G.C.M.G., (xovernor of New Zealand. His E.xcellency 8ir Anthony Musgrave, G.C.M.G., Governor of Queensland (deceased). His Excellency Sir William Cleaver F. Robinson, G.C.M.G., Governor of South Australia. His Excellency Sir Robert Claude Hamilton, K.C.R., (Governor of Tasmania. His Excellency Sir Frederick Napier Bijoome, K.C.M.G., Governor of Western Australia. His Excellency Sir John B. Thurston, K.C.M.G., Governor of Fiji. WITH THE SPECIAL COUNTENANCE AND SUPPORT OF The Hon. Duncan Gillies, Premier of Victoria, and Her Majesty's Ministers in Victoria. iv INTKKCOLONIAL MEDICAL CONGKKSS OF AUSTRALASIA. PRESIDENT OF THE CONGRESS. Thomas Nagiiten FitzGerald, F.?i. C.S.I. VICE-PRESIDENTS OF THE CONGRESS: CiiAKLES Morton Anderson, M.R.C.S. Eat;-., President of the Canterbury Medical Association. Thomas Chambers, F.R.C.P., F.R.C.S. Ed., &c., President of the New South "Wales Branch of the British Medical Association. William Edward Collins, M.B. Lond., M.R.C.S. Eng-., President of the Wellington Medical Association. Daniel Colquhoun, M.D. Lond., M.R.C.P. Lond., M.R.C.S. Eng., President of the Otago Medical Association. The Hon. John Mildred Creed, M.R.C.S. Eng., L.R.C.P. Ed., M.P. (Sydney). Frederick William Edmund Dawson, M.R.C.S. Eng., L.R.C.P. Ed., President of the New Zealand Medical Association and of tlie Auckland Medical Association. Henry Croker Garde, F.R.C.S. Ed., Maryliorough (Queensland). AVilliam Panton Grhjor, L.R.C.S. Ed., President of the Southland Medical Association. John Hugh Harricks, M.R.C.S. Eng., L. et L.M.K.Q.C.P.T., President of the Maryborough (Queensland) Medical Societ}-. Philip Sydney Jones, M.D. liond., F.R.C.S. Eng. (Sydney). Samuel Thomas Knaggs, M.D., Ch. M. Aber., F.R.C.S. L, President of tlie Medical Section of the Royal Society of New South Wales. Joseph Henry Little, M.B. et CM. Edin., President of tlie Medical Society of Queensland. Cosby William Morgan, M.D. Brux., M.R.C.S. Eng., Newcastle (N.S.AV.) Henry Hayton Iiadcliffe, M.R.C.S. Eng., President of the Ballarat District Medical Society. Thomas Rowan, M.D. Sydney, F.R.C.S. Ed., President of the A^ictorian I '.ranch f)f the Ih'itish Medical Association. .Iames Pati;ick Ryan, M.K.Q.C.P.L, L.R.C.S.I., President of the Medical Society of Victoria. Tmomas Christie Smart,«F.R.C.S. Ed. (Hobart). Edward Charles Stirling;, M.A., M.D. Cantab., F.R.C.S. Eng., President of tlie Soutli Australian Branch of the Britisli Medical Association. Joseph Cooke Verco, M.D. Lond., F.R.C.S. Eng. (Adelaide), President of tlie First Session of the Conajress. OFFICE-BKAHERS. TREASURER. George Ckaiiam, M.D. Melb., M.R.C.S. Eng., Riclnnoncl. GENERAL SECRETARY. Pkofessok H. B. Allex, M.D. et B.S. Melb., Melbourne University. ASSOCIATE SECRETARIES. J. W. Barrett, M.D. et M.S. Melb., F.R.C.S. Eng. G. A. Syme, M.B. et M.S. Melb., F.R.C.S. Eng. EXECUTIVE T. (). F. Alsop, M.B. et CM. Edin., M.R.C.S. Eng. W. Balls-Headlev, M.D. et M.C. Cantab., M.R.C.R Lond. A. Bennett, M.D. et CM. Abeixl., M.R.C.S. Eng. F. D. Bird, M.B. et M.S. Melb., M.R.C.S. Eng. S. D. Bird, M.D. St. A., M.R.C.S. Eng. T. A. Bo WEN, M.R.C.S. Eng., L.K.Q.C.P.I. A. C Brownless, M.D. St. And., F.R.C.S. Eng. S. J. Burke, M.R.C.S. Eng., L.K.Q.C.P.I. J. G. Carstairs, M.D. Edin., L.R.C.S. Ed. A. CoLQUiiouN, M.B. Glas., L.R.C.S. Ed. J. Cooke, M.R.C.S. Eng. W. H. Cutts, M.D. Edin. R. B. Duncan, F.R.C.S. Ed. C Duret, M.D. Paris. W. H. Embling, L.R.C.P. Lond., L.F.P.S.G. G. H. Fetiierston, M.D. Melb., L.F.P.S.G. J. W. Y. FisiiBOURNE, M.B. et Ch. M. Dub. T. F. Fleetwood, M.B. Dub., F.R.CS.I. F T. West Ford, M.R.C.S. Eng. COMMITTEE. T. Foster, M.R.C.S. Eng. T. M. GiRDLESTONE, F.R.C.S. Eng. C E. GooDALL, M.B., B.S. Melb. D. Grant, M.D. et CM. Edin. A. S. Gray, M.R.C.S. Eng. Professor G. B. Halford, 31. D. St. A., M.R.C.S. Eng. Colin Henderson, M.D. et CM. Aberd. L. Henry', M.D. Wurzbujg, L.R.C.P. Lond. T. Hewlett, M.R.C.S. Eng. E. Hinciicliff, M.D. Edin., M.R.C.S. Eng. J. Jackson, M.D. Lond., M.R.C.S. Eng. E. M. James, M.R.C.S. Eng. J. Jamieson, M.D. et CM. Glas. H. JoNASSON, M.D. Wurzburg. The Hon. G. LeFevre, M.D. et CM. Edin., M.L.C. A. J. R. Lewellin, M.B. et B.S. Melb. P. Moloney, M.B. Melb. W. Moore, M.D. et M.S. Melb. W. Morrison, M.D. et CM. Cilas. J. V. McCreery, L.R.CS.I. W. McCrea, M.B. Lend., M.R.C.S. Eng. P. H. MacGillivray, M.R.C.S. Eng. J. R. MacInerney, L.K.Q.CP.I., L.R.CS.I. INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA J. C. McKee, L.R.C.P. et S. Ed. J. E. Neild, M.D. et B.S. Melb., L.S.A. Loud. J. Nicholson, M.D. Edin., M.R.C.S. Eng. H. M. O'Hara, L.K.Q.C.P.T., L.R. C.S.I. F. Peipers, M.D. Berlin. O. Penfold, M.R.C.S. Eng. A. J. W. PETTIC4REW, M.R.C.S. Eng. R. PiNCOTT, M.R.C.S. Eng. R. D. PiNNOCK, M.B. et CM. Glas. R. Power, L.R.C.P. Ed., L.R.C.S.I. H. H. Radcliffe, M.R.C.S. Eng. W. B. Rankin, F.R.C.S. Ed. J. A. Reid, M.D. et CM. Aber. James Robertson, M.D. Aber., L.R.C.S. Ed. T. Rowan, M.B. Melb., M.D. Sydney, F.R.C.S. Ed. J. T. RuDALL, F.R.C.S. Eng. C S. Ryan, M.B. et CM. Edin. J. P. Ryan, M.K.Q.C.P.I., L.R.C.S.I. A. Shields, M.D. Edin. C Smith, M.D. Lond., M.R.C.S. Ens. D. Skinner, M.B. et CM. Aber. S. Maberly Smith, M.R.C.S. Eng L.R.C.P. Ed. W. Beattie Smith, F.R.C.S. Ed., L.R.C.P. Ed. W. Snowball, M.B. Melb., L.R.C.S. Ed. J. W. Sprin(;thorpk, M.D. et B.S. Melb., M.R.C.P. Lond. W. H. Syme, L.R.C.P. Lend., L.R.CS.L M. B. Thomson, M.B. et CM. Edin. J. Tremearne, M.R.C.S. Eng. D. Turner, L.R.C.P. Lond., L.R.C.S. Ed. W. B. Walsh, M.D. Dub., F.R.CS.L J. H. Webb, M.R.C.S. Eng., L.R.C.P. Lond. W. P. Whitcombe, M.R.C.S. Eng. H. C WiGG, M.D. Edin., F.R.C.S., Eng. J. Williams, M.D. Edin., M.R.C.S. Eng. J. J. E. WiLLMOTT, M.D. Aber., M.R.C.S. Eng. H. WOOLDRIDGE, F.R.C.S. Eng. R. YouL, M.D. St. A., M.R.C.S. Eno-. ORGANISATION SUB-COMMITTEE. The President. A. C Brownless, M.D. G. Graham, M.D. E. M. James, M.R.C.S. J. Jamieson, M.D. P. Moloney, M.B. W. McCrea, M.B. J. E. Neild, M.D. J. Robertson, M.D. J. T. RuDALL, F.R.C.S. J. Williams, M.D. The Secretary. RECEPTION The President. W. Balls-Headlky, M.D. A. C Brownless, M.D. F. T. West Ford, M.R.C.S. COMMITTEE. E. M. James, M.R.C.S. P. Moloney, M.B. C S. Ryan, M.B. R. YouL, M.D. TiiK Secretary, SECTIONAL OFFICERS. LITERARY COMMITTEE. The President. J. H. Webb, M.R.C.S. J. Jamieson, M.D. The Secretary. J. E. Neild, M.D. The Associate Secretaries. The Secretaries of Sections and Sub-Sections. vii LOCAL SECRETARIES. Nexo South Wales Philip Edward Muskktt, L.R.C.P. et S. Ed. (Sydney.) Queensland ... Francis Washington Everard Hare, M.B. Durh., M.R.C.S. Eng. (Brisbane). South Australia ... Ben.jamin Poulton, M.D. Melb., M.R.C.S. Eng. (Adelaide). Neio Zealand ... Joseph Osborne Closs, M.B., CM. Edin. (Invercargill). Western Australia John Rae Menzies Thomson, M.B., B.S. Melb. (York). Tasmania ... James M'Imery Pardey, M.B., B.S. Melb. (Launceston). LIST OF SECTIONS AND SECTIONAL OFFICERS. SECTION OF MEDICINE. President ... The Hon. William Frederick Taylor, M.D., Queen's College (Kingston, Canada), M.R.C.S. Eng., M.P. (Brisbane). Vice-Presidents ... Daniel Colquhoun, M.D. Lond,, M.R.C.P. Lond., M.R.C.S. Eng. (Dunedin). John Davies Thomas, M.D. Lond., F.R.C.S. Eng., L.R.C.P. Lond. (Adelaide). Secretary ... James .Jamieson, M.D. (Melbourne). INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. President Vice-Presidents Secretary SECTION OF SURGERY. Edward Charles Stirling, M.A., M.D. Cantab., F.R.C.S. Eng. (Adelaide). Charles Henry Haines, M.A., M.D. Queen's Univ. Ii-el., F.R.C.S.I. (Auckland). Henry Wideniiam Maunsell, M.B. Dub., M.R.C.S. Eng. (Dunedin). Richard Rendle, F.R.C.S. Eng. (Brisbane). Frederick Dougan Bird, M.B., M.S. (Melbourne). SECTION OF HYGIENE, FORENSIC AND STATE MEDICINE. President ... Henry Norman MacLaurin, M.A., M.D. Edin., LL.D. St. A. (Sydney). Vice-Presidents ... Alexander Johnston, M.D. St. A., M.R.C.S. Eng. (Wellington). Thomas Christie Smart, F.R.C.S. Ed. (Hobart). Alfred Robert Waylen, M.D. St. A., M.R.C.S. Eng. (Perth). Secretary ... John William Springtiiorpe, M.D. (Melbourne). SECTION OF ANATOMY AND PHYSIOLOGY. President ... Professor T. P. Anderson Stuart, M.D., CM. Edin. (Sydney). Vice-President ... Professor Archibald AVatson, M.D. Pai-is and Gottingen, F.R.C.S. Eng. (Adelaide). Secretary ... James William Barrett, F.R.C.S. (Melbourne). SECTION OF PATHOLOGY. President ... William Camac Wilkinson, M.D. Lond., M.R.C.P. Lond., M.R.C.S. Eng. (Sydney). Secretary ... Henry Maudsley, M.D. (Melbourne). SECTION OF OBSTETRICS AND GYNECOLOGY. President ... Ferdinand Campion Batchelor, M.D. Durham, F.R.C.P. Ed., M.R.C.S. Eng. (Dunedin). Vice-Presidents ... Richard Stonehewer Bright, M.R.C.S. Eng. (Hobart). James Hill, M.D. Edin., F.R.C.S. Ed. (Brisbane). Edward Willis Way, M.D. Edin., M.R.C.S. Eng. (Adelaide). Secretary ... Felix Meyer, M.B. (Carlton). SECTIONAL OFFICERS. IX SECTION FOR DISEASES OF THE EYE, EAll AiNI) THROAT. President ... -Mai{K Johnston Symons, M.D., CM. Ediii. (Adelaide). Vice-Presidents ... Ciiakles Morton Anderson, M.R.C.S. Eiig. (Cliristcluirch). Andrew John Brady, L.K.Q.C.P.I. et L.R.C.S.I. (Sydney). Thomas Evans, M.R.C.S. Eng. (Sydney). Secretarijfor Diseases of the Eye : .James Jackson, M.D. (Melbourne). Secretary for Diseases of the Ear and Throat: Charles Lesin(;iiam Maynard Iredell, M.R.C.S. (Melbourne). SECTION OF PSYCHOLOGICAL MEDICINE. President ... Frederick Norton Manning, M.D. St. A., M.R.C.S. Eng. (Sydney). Vice-Presidents ... Walter Edward Hacon, L.R.C.P. Lend., M.R.C.S. Eng. (Christchurch). Alexander Stewart Paterson, M.D. Edin., L.R.C.S. Edin. (Adelaide). Richard Battersby Scholes, M.B., CM. Edin. (Brisbane). Secretary ... William Beattie Smith, F.R.C.S. (Ararat). SECTION OF PHARMACOLOGY. President ... Baron Sir Ferdinand Von Mueller, M.D., Ph. D., K.C.M.G., F.R.S. Vice-President ... Thomas Dixson, M.B., CM. Edin. (Sydney), Secretary ... David Grant, M.D. (Melbourne). SECTION FOR DISEASES OF THE SKIN. President ... James Patrick Ryan, M.K.Q.CP.L, L.R.C.S.I. (Melbourne). Secretary ... Robert Andrew Stirling, M.B. (Melbourne). SECTION FOR DISEASES OF CHILDREN. President ... William Snowball, M.B., B.S. Melb., L.R.C.S. Ed. (Melbourne). Secretary ... Arthur Jeffreys AVood, M.B. (Melbourne). ROLL OF MEMBERS OF CONGRESS. Adam, G. Roth well .. Adam, J. Basil Agnew, The Hon. J. W Aitchison, A. S. Aitchison, E. Allen, H. B. Alsop, T. O. Fabian Amess, James Anderson, A. V. M. Anderson, C. M. Anderson, E. W. Anderson, J. Anderson, J. F. Andrews, W. Annand, G. Appleyard, J. Armstrong, G. A. Ax'mstrong, \V. Astles, H. E. Backhouse, J. B. Bage, Charles Baird, J. C. Balls-Headley, W. Bancroft, J. Bancroft, T. L. Barker, W. Barnard, C. E. Barr, T. J. Barrett, J. W. M.B., CM. Edin. M.B., Ch. M. Glas. M.D. Glas., M.R.C.S. Eng. M.B., B.S. Melb. M.B., B.S. Melb. M.D., B.S. Melb. M.B., CM. Edin., M.R.C.S. Eng. M.B., B.S. Melb. M.B., B.S. Melb. M.R.C.S. Eng. M.D., B.S. Melb., L.R.C.S. Ed. L R.C.P. et. S. Ed. L.R.C.P. et. S.Ed. M D., B.S. Melb. M.D., B.S. Melb., M.R.C.S. Eng. M.R.C.S. Eng. L. R.C.P. et. S. Ed. M.D., B.S. Melb. M.D. St. A., F.R.CP. Ed. M.B., B.S. Melb. M.D., B.S. Melb. M.B., B.S. Melb. M.D.,C.M.Cantab., F.R.CP. Lond. M.D. St. A., M.R.C.S. Eng. M.B., CM. Edin. M.R.C.S. Eng. M.D., Ch. M., Abei M.R.C.S. Eng. L.R.CP.et.S.Ed. . M.D., M.S. Melb., . F.R.C.S. Enff. Melbourne, Vic. Beaufoi't, Vic. Hobart, Tas. Albert Park, Vic Albert Park, Vic. Melb. Univ., Vic. Hawthorn, Vic. Tungamah, Vic. Prahran, Vic. Christchurch, N.Z. Hawthorn, Vic. Footscray, Vic. Cootamundra,N.S.W. Melbourne, Vic. St. Kilda, Vic. Longford, Tas. East Melbourne, Vic. Fitzroy, Vic. Melbourne, Vic. Brighton, Vic. South Yarra, Vic. Carlton, Vic. Melbourne, Vic. Brisbane, Q. Brisbane, Q. Albert Park, Vic. Hobart, Tas. Hawthorn, Vic Melbourne, Vic UOLL OF MKMBERS. Batchelor, F. C. Bennett, A. Bennett, F. A. Bennie, P. B. Bett, J. W. Bickle, L. W. Bii-ch, L. Bird, E. J. Bird, F. D. Bird, 8. D. Bird, W. J. Black, A. G. Blaxland, E. G. Blaxland, H. Bonnetin, F. H. Borthwick, T. Bowe, F. Bowen, T. Aubrey Bowman, R. Boyd, Dr. Brady, A. J. Branson, G. B. Brennan, J. M. Brett, J. T. Bright, R. S. Brock, E. Brown, H. R. Brown, Valentine Brown, W. Ikown, W. H. M.D. Durh., F.R.C.P. Ed. M.D., Ch. JNI. Aber., L.R.C.P. Lond. M.D., Ch. M. Aber. M.D., B.H. Melb. . M.B,,Cli. M. Aber.. M.R.C.S. Eng., L.R.C.P. Lond. M.B., B.S. Melb. . M.B., B.S. Melb. . M.B., M.S. Melb., . M.R.C.S. Eng. M.D. St. A., L.R.C.P. Lond. M.B., B.S. Melb. . M.B., Ch. M. Gla.s. . M.R.C.S. Eng., L.R.C.P. Lond. M.R.C.S. Eng., L.R.C.P. Lond. M.R.C.S. Eng., L.R.C.P. Lond. M.B., CM. Edin. . M.B. Lond., M.R.C.S. Eng. M.R.C.S. Eng., L.K.Q.C.P.L M.B., CM. Edin., . M.R.C.S. Eno. L.K.Q.C.P.L, L.R.CS.L M.R.C.S. Eng., L.R.C.P. Ed. L.F.P.S.G. M.R.C.S. Eng. M.R.C.S. Eng. M.R.C.S. Eng. L.R.C.P. et S. Ed. M.B. Dub. M.B., CM. Edin. M.R.C.S. Entr. Dunedin, K.Z. Hamilton, \'ic. Bairnsdale, \'ic. Melbourne, Vic. Richmond, Vic. Adelaide, S.A. Tarra\ ille, A'ic. Northcote, Vic. Melbourne, Vic. Melbourne, \io. Boort, ^'ic. Carlton, Vic. Sydney, N.S.W. Sydney, N.S.W. Stockton, New- castle, N.S.W. Kensington, S.A. Maryborough, Q. Melbourne, Vic. Parramatta, N.S.W. United States. Sydney, N.S.AV. Tungamah, Vic. Corryong, Vic. Melbourne, Vic. Hobart, Tas. Kilmore, Vic. Snowtown, S.A. Melbourne, Vic Dunedin, N.Z. Maffra, Vic. XU INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Brownless, A. C. ... M.D. St. A., ... Melbourne, Vic. Brummitt, R. Bryant, H. W. Burke, S. J. Burton, J. Biittner, A. Byrne, W. S. Campbell, W. B. Carrutliers, C. U. Carstairs, J. G. Chambers, T. Chapman, J. T. Chisholm, E. Cliishohn, ^Y. Clarke, C. A. Dagnall Clarke, H. St. John Cleland, W. L. Clenclinnen, F. J. Clcss, J. (). Clubbe, C. P. B. Coane, J. Cobb, F. Cock burn, Hon. J. A. Cohn, M. Cole, F. H. Collingwood, D. Colquhoun, A. M.D. St. A., F.R.C.S. Eng. M.R.C.S. Eng. L.R.C.P. et S. Ed. M.R.C.S. Eng. L.K.Q.C.P.I. M.D.Toronto, M.R.C.S. Eng. M.D. Berlin, F.R.C.S. Ed. M.B., Ch. M., T.C.D L.K.Q.C.P.I., L.R.C.S.I. M.D. Edin., L.R.C.S. Ed. F.R.C.P., F.R.C.S. Ed. L.R.C.P. et S. Ed. M.D. St. A., M.R.C.S. Eng. M.D. Lond., M.R.C.S. Eng. M.B. Lond. F.R.C.S. Eng. M.B., CM. Edin. M.D., D. Ch. Brux L.R.C.P. Lond. M.B., CM. Edin. M.R.C.S. Eng. L.R.C.P. Lond. L.R.C.P. Ed., L.R.CS.L M.R.C.S. Eng., M.D. Lond., M.R.C.S. Eng. M.D. Copenhagen M.B., B.S. Melb. M.D. Lond., F.R.C.S. Eng. M.B. Glas., L.R CS. Ed. Kooringa, S.A. Williamstown, Vic. Melbourne, Vic. Richmond, Vic. Melbourne, Vic. Brisbane, Q. St. Arnaud, Vic. Sydney, N.S.W. Geelong, Vic. Sydney, N.S.W. Drysdale, Vic. Ashfield, Sydney, N.S.W. Sydney, N.S.W. St. Leonard's, Sydney, N.S.W. Richmond, Vic. Adelaide, S.A. Hawksburn, Vic. Invercargill, N.Z. Rand wick, N.S.W. Brighton, Vic. Fitzroy, Vic. Adelaide, S.A. Melbourne, Vic. Carlton, Vic. Sydney, N.S.W. Sandhurst, Vic. UOLL OF MICMHRKS. Colquhouu, A. G. Colti[uhoun, P. Connor, 8. Cooke, J. Cookson, J. Corljin, T. W. Courtenay, J. H. Coutie, W. H. Cox, J. Crago, W. H. Craig, W. J. Crivelli, M. Creed, Hon. J. M. Cross, W. J. Crossen, H. Crowther, F. S. Cunningham, P. H. Curtis, H. C. Cuscaden, G. Cussen, G. E. Cutts, W. H., sen. Daisli, W. C. Davenport, A. J. Davies, T. S. Dawes, R. St. M. Dawson, F. W. E. Dawson, — DeZouche, I. Dick, T. T. Dickinson, G. W. Dixson, T. Dobbin, W. S. Dowlinfj, F. M.B., B.S. Melb. ., M.D. Lond., M.R.C.P. Lond. M.D. Q.U.I. M.R.C.S. Eng. M.P,., B.S. Melb. ., M.R.C.S. Eng. L.R.C.P. Lond. .. M.B., B.S. Melb. . M.D. Melb., M.R.C.S. Eng. M.R.C.S. Eng., L.R.C.P. Lond. M.B., B.S. Melb. .. M.D. Paris M.R.C.S. Eng., L.R.C.P. Ed. M.B.Toronto, L.R.C.P. et S. Ed. L.F.P.S.G. M.B., B.S. Melb. .. M.B., Ch. M. Glas. M.R.C.S. Eng. L.R.C.P. etS. Ed. .. M.B., B.S. Melb. .. M.D. Edin. M.D., B.S. Melb. .. M.B. Lond., M.R.C.S. Eng. L.R.C.P. et S. Ed... M.R.C.S. Eng. M.R.C.S. Eng. M.D.Q.U.L, M.R.C.S. Eng. M.D. Edin., M.R.C.S. Eng. M.B., CM. Edin., M.R.C.S. Eng. M.B., CM. Edin. . M.B., Ch. B. Dul) F.R.CS.L M.Pk.CS. Enir. Melbourne, A'ic. Dunedin, N.Z. Coleraine, Vie. Prahran, Vic. Adelaide, S.A. Adelaide, S.A. Melbourne, Vic. Sydney, N.S.W. Melljourne, Xk-. Woollooniooloo, N.S.W. Melbourne, Xif. Albert Park, Vic. Woollahra, N.S.W. Horsham, Vic. Melbourne, Vic. Melbourne, Vic. Talbot, Vic. Semaphore, S.A. Port Melbourne, Vic. Melbourne, Vic. Hawthorn, Vic. South Melbourne, Vic. St. Kilda, Vic. Benalla, Vic. Gawler, S.A. Auckland, N.Z. s.s. " Massilia " Dunedin, N.Z. Melbourne, Vic. INIoonee Ponds, Vic. Sydney, N.S.W. BruT\swick, Wc. Riclimond, Vic. INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Doyle, Patrick Drake, F. J. Duigan, C. B. Duncan, J. Duncan, R. B. Dyring, C. P. W. Eastwood, F. Eccles, J. V. Elliott, C. B. Ellis, H. H. Embling, H. A. Embling, W. H. Erson, E. G. L. Evans, J. H. Evans, T. Faithfull, R. L. Faulkner, AV. J. Fell, W. Ferguson, H. L. Fetherston, Gr. H. Fetherston, R. H. Fetherstonhaugh, C. Fiaschi, T. Fjeldstad, A. H. Finlay, W. Fischer, C. Fishbourno, J. W. Y. Fisher, A. Fisher, T. C. FitzGerald, T. N. Fleetwood, T. F. M.D., Ch. M. Q.U.T. M.B. Melb. L.R.C.P. et8. Ed. .. M.B., CM. Aber. .. F.R.C.S. Ed. M.B., B.S. Melb. M.B., B.S. Melb. M.D. Michigan L.R.C.P. Ed., M.R.C.S. Eng. M.B., Ch. B. Dub. ... M.B., B.8. Melb., L.R.C.P. Ed. L.R.C.P. Lond., ... L.F.P.S.G. L.R.C.P. Ed. M.B., B.S. Melb. ... M.R.C.S. Eng. M.D. Columbia College, N.Y., L.R.C.P. Lond. M.D., Ch. M. Q.U.I. M.B. Lond. F.R.C.S.I. M.D. Melb., L.F.P.S.G. M.D., CM. Ed., ... L.R.CS.I. M.B., Ch. M. Dub., L.R.CS.I. M.D., Ch. ^l. Pisa... Med. Cand. Univ. ... Christiania M.D. Cooper Med. Coll. San Francisco M.D. Halle et Wur/., M.R.C.S. Eng M.B., M.Ch. Dub.... M.R.C.S. Eng. M.D., M. Ch., T.C.D. F.R.CS.T. M.B. Dub., F.R.C.S.I. Hawthorn, Vic. Kew, Vic. Richmond, Vic. Bairnsdale, Vic. Kyneton, Vic. Coburg, Vic. Ballarat, Vic. Melbourne, Vie. Geraldton, W.A. Double Bay, N.S.W. Hawthorn, Vic. St. Kilda, Vic. Prahran, Vic. Adelaide, S.A. Sydney, N.S.W. Sydney, N.S.W. Kyneton, Vic. Wellington, N.Z. Dunedin, N.Z. Prahran, Vic. Carlton, Vic. Nth. Melbourne, Vic. Sydney, N.S.W. Sydney, N.S.W. Bathurst, N.S.W. Sydney, N.S.W. Moonee Ponds, Vic. Melbourne, Vic. Sydney, N.S.W. Melbourne, Vic. Warrnambool, Vic. ROLL OF MEMBERS. Fleming, H. H. Fletclier, A. A. Fletcher, E. Flett, W. S. Flynn, J, J. Ford, F. T. West Foreman, J. Foster, T. Fox, G. Fox, W. R. Frizelle, T. Fytie, B. Fyffe, E. H. Gamble, H. W. B. Garde, H. C. Gardner, W. Garliek, T. A. Gault, E. L. Gibson, J. Giles, W. A. Girdlestone, T. M. Goodall, C. E. Graham, G. Grant, D. Gray, A. S. Griffith, C. A. Griffith, J. de B. Grigor, W. P. Gurdon, E. J. Hacon, W. E. Haig, W. Haines, C. H. Halford, G. B. M.B., Ch. B. Dub. ... M.D., B.S. Melb., ... M.R.C.8. Eng. .M.R.C.S. Eng. M.D., CM. Edin. ... M.B., Ch. M. R.U.I. M.R.C.S. Eng. L.R.C.P. Ed., M.R.C.S. Eng. M.R.C.S. Eng. ... M.R.C.S. Eng., ... L.R.C.P. Ed. L.R.C.P. etS. Ed.... M.D., M. Ch. Q.U.]. M.R.C.S. Eng. L.R.C.P. Lond. M.B., Ch.M. Glas.... L.R.C.S. Ed. F.R.C.S. Ed. M.D., Ch.M. Glas. ... M.B., B.S. Melb. ... M.B., B.S. Melb. ... M.B., CM. Edin. ... F.R.C.S. Eng. M.B., B.S. Melb. ... M.D. Melb., M.R.C.S. Eng. M.D., CM. Edin. ... M.R.C.S. Eng. M.R.C.S. Eng. M.B., M.Ch. Dub.... L.R.CS. Ed. M.R.C.S. Eng., L.R.C.P. Ed. M.R.C.S. Eng. L.R.C.P. Lond. M.D. Maryland, U.S. M.D. Q.U. L, F.R.CS.I. M.D. St. A., M.R.C.P. Lond., M.R.C.S. Eng. Donald, Vic, Carlton, Vic. Carlton, Vic. Fitzroy, Vic. Bairnsdale, Vic. Melbourne, Vic. Sydney, N.S.W. Colac, Vic. Ruthergleii, Vic. Fitzroy, Vic. Roebourne, W.A. Fitzroy, Vic. Fitzroy, Vic. Walhalla, Vic. Maryborough, Q. Adelaide, S.A. Murtoa, Vic. Alfred Hospital, Vic. Windsor, N.S.W. Adelaide, S.A. Melbourne, Vic. St. Kilda, Vic. Richmond, Vic. Melbourne, Vic. Melbourne, Vic. Elsternwick, Vic. Balaclava, Vic. Invercargill, X.Z. Brighton, Vic. Christchurch, N.Z. Melbourne, Vic. Auckland, N.Z. Melbourne, Vic. INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Hamilton, A. A. Hamilton, J. A. G. . Hamilton, T. K. Haiicock, R. Hankins, G. T. Hardy, C. H. W. Hare, F. W. E. Harkness, E Harricks, F. M. Harricks, J. H. Harrison, W. A. Harvey, R. R. Hayman, F. D. Hay ward, W. T. Heffernan, E. B. Hendei'son, A. V. Henderson, C. Henry, L. Henry, T. J. Hewlett, T. Hill, J. Hinchcliti; E. Hocken, T. M. Hodi^son, T. Honman, A. Hood, A. J. Hooper, J. W. Dunbar Hope, J. W. Hope, T. C. Home, G. Howard, G. Howitt, G. M.B., Ch. B. Dub. .. M.B. Dub., L.R.C.S. Ed. M.D. Dub., F.R.C.S.I. M.R.C.S. Eng. M.R.C.S. Eng. M.B., B.S. Melb. .. M.B. Durh., M.R.C.S. Eng. L.R.C.R etS. Ed. .. M.K.Q.C.P.I., L.R.C.8.T. M.R.G.S. Eng., L.K.Q. C.P.I. M.B., CM. Edin. .. M.B., B.S. Melb. .. M.R.C.S. Eng. M.R.C.S. Eng., L.K.Q.C.P.I. M.D., B.S. Melb. .. M.B., B.S. Melb. .. M.D., Ch. M. Aber., L.R.C.S. Ed. M.D. Wjirz., L.R.C.P. Lond. L.R.C.P. et S. Ed.... M.R.C.S. Eng. M.D. Edin., F.R.C.S. Ed. M.D. Edin., M.R.C.S. Eng. M.R.C.S. Eng. M.B., B.S. Melb. .. M.R.C.S. Eng. M.B., Ch. M. Glas.... L.R.C.P. et S. Ed. M.R.C.P. Ed. M.B., Ch. M. Glas. M.B., B.S. Melb. M.D., B.S. Melb. M.B., B.S. Melb. Adelaide, S.A. Kapunda, S.A. Laura, S.A. Brisbane, Q. Sydney, N.S.W. Ballarat, Vic. Brisbane, Q. Surrey Hills, Vic. St. Kilda, Vie. Maryborough, Q. Hawthorn, Vic. Creswick, Vic. Harrow, Vic. Norwood, S.A. Fitzroy, Vic. Camberwell, Vic. Castlemaine, Vic. Brunswick, Vic. Sydney, N.S.W. Fitzroy, Vic. Brisbane, Q. Sandhurst, Vic. Dunedin, JST.Z. Sunbury, Vic. Williamstown, Vic. Clarence River, N.S.W. Melbourne, Vic. Fremantle, W.A. Geelong, Vic. Clifton Hill, Vic. North Fitzroy, Vic. Melbourne, Vic. KOLL OF MEMBERS. Hudson, J. M.I 5. Loud., M.R.C.8. Eng. Nelson, N.Z. Hudson, R. F. M.D. St. A., L.F.P.S.a. Ballarat, Vic. Hull, W. M.D. Loud., M.R.C.S. Sydney, KS.W. Hurst, G. M.B. Lond., M.B., CM. Edin. Sydney, N.S.W. Ick, T. E. M.B., B.S. Melb. ... Albert Park, Vic. Inglis, E. M. . M.B., CM. Edin., ... L.R.CS. Ed. Kew, Vic. Iredell, C. L. M. M.R.C8. Eng., L.R.CP Ed. Melbourne, Vic. Irving, J. M.D. Edin., M.R.CS. Eng. Christchurch, N.Z. Irving, J. A. L.R.CP. Ed., L.R.CS.I. Caulfield, Vic. Jack, R. K L.R.CP. etS. Ed. ... Stawell, Vic. Jackson, H. W. M.R.CS. Eng., L.R.CP. Ed. Sydney, N.S.W. Jackson, J. M.D. Lond., M.R.CS. Eng. Melbourne, Vie. Jakins, W. V. M.R.CS. Eng., ... L.R.CP. Ed. Melbourne, Vic. James, E. IVI. M.R.CS. Eng. Melbourne, Vic. James, T. M.R.CS. Eng. Moonta, S.A. Jamieson, J. M.D., Ch. M. Glas. Melbourne, Vic. Jay, Melville R. H. ... M.R.CS. Eng., ... L.R.CP. Lond. Adelaide, S.A. Jee, H. C. M.R.CS. Eng. L.R.CP. Ed. Alexandra, Vic. Jenkins, E J. M.D. Oxon., M.R.CP. Lond., M.R.CS. Eng. Sydney, N S. W Jermaine-Lulham, F. S. M.R.CS. Eng L.R.CP. Lond. Melbourne, Vic Johnston, A. M.D. St. A., M.R.CS. Eng Wellington, N.Z Johnston, A. A. M.K.Q.CP.L, LR.CS. Ed. Moruya, N.S.W Johnston, J. Couper ... M.H., CM. Edin. ... St. Kilda, Vic. John.ston, J. M.B., Cli. M. Glas. Williamstown, Vic Jonasson, H. M.I). Wur/.. Melbourne, Vic. Jone.s, P. Sydney M.D. Lond., F.R.CS. Eng. Sydney, N.S.W. XVUl INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Joske, A. Joyce, J. F. Keenan, A. J. W. Kennedy, J. \V. Kennedy, P. Kenny, A. L. Keogh, A. G. Kerr, J. Kilpatrick, W, Kingsbury, J. Kirtikar, K. R. Knaggs, S. T. Lalor, J. Lane, C. T. Lane, T. Lawrence, Dr. Le Fevre, Hon. G. Lenipriere, C. L. Lejidon, A. Lethbridge, C. F. Lewellin, A. J. R. Liddle, P. H. Lilie, H. Lillies, H. Little, J. H. Lloyd, F. Long, M. H. Longden, F. R. Loosli, R. J. M.B., B.S. Melb. ... L.R.C.P. etS. Ed. ... M.D., Ch. D. Brux., L.R.C.S. Ed. F.R.C.S.L, M.K.Q.C.P.I. L.R.C.S.L, L.K.Q.C.P.L M.B., B.S. Melb. ... M.B., Ch. M. Glas.... M.B., Ch. M. Glas.... M.B., B.S. Melb. ... M.D. Univ. Pennsyl- vania M.R.C.S. Eng., L.R.C.P. Lond. M.D., Ch. M. Aber., F.R.C.S.L M.D.,Ch.D. Brux.,... L.R.C.S.L M.B., B.S. Melb. ... L.R.C.S.L, L.K.Q.C.P.I. M.D., CM. Edin., M.L.C. M.B., CM. Edin. M.D. Lond., M.R.C.S. Eng. M.R.C.S. Eng. M.B., B.S. Melb., L.K.Q.C.P.L M.B., B.S. Melb. M.D. Univ. Bonn. M.R.C.S. Eng., L.R.C.P. Ed. M.B., CM. Edin. M.D. Syd.,L.R. C.S.I M.D. (Univ. City .. of New York), L.K.Q.C.P.I. L.R.C.P. etS. Ed... M.B., B.S. Melb. .. Prahran, Vic. Fitzroy, Vic. "Windsor, Vic. Hay, N.S.W. Albury, N.S.W. Melbourne, Vic. St. Kilda, Vic. Newcastle, N.S.W. Yarra Glen, Vic. Sydney, N.S.W. Thana (Bombay), India Sydney, N.S.W. Richmond, Vic. Camberwell, Vic. Inverell, N.S.W. Malvern, Vic. Melbourne, Vic. South Yarra, Vic. Adelaide, S.A. Alexandra, Vic. Melb. Hospital, Vic. Beechworth, Vic. Moree, N.S.W. Armadale, Vic. Brisbane, Q. Melbourne, Vic. Sydney, N.S.W. Buninyong, Vic. Camberwell, Vic. ROLL OP MEMBERS. Lynch, p. McAllister, J . F. McCartliy, C. McCartliy, C. L. MacColl, D. S. MjicCorniick, A. McCrea, W. McCreery, .J. V. M'Culloch, S. H. MacDoiiald, Archibald MacDonald, il. Gordon M'Donnell, E. P. McFarlane, C. C. MacFarlane, W. H. ... MacGibbon, W. MacGillivray, P. H. ... MacGregor, 8ir W. Maclnerney, J. R. Maclntyre, J. M. McKee, J. C. MacKenzie, J. H. M'Killop, H. Mackintosli, J. S. MacKnight, C. M. MacLaiirin, H. N. Maclean, H. K. McMillan, T. L. Maclellan, J. N. E. ... McMullen, H. L.R.C.P. etS. Ed. ... M.B., B.S. Melb. ... ]\l.D. Melb., L.F.P.8.G. M.B., B.S. Melb. ... M.B., Ch. M. Glas. M.B., CM. Edin., ... M.R.C.8. Eng. :M.B. Lond., M.R.C.S. Eng. L.R.C.S.I. M.B., CM. Edin. ... M.D. Med. Coll. ... Pennsylvania L.R.CR Ed., L.F.P.S.G. L.K.Q.CP.L, L.R.CS.I. L.R.CP. et S. Ed.... M.B., B.S. Melb. ... M.D. Brux., L.R.CP. et S. Ed. M.R.CS. Eng. M.D. Aber., L.R.CP. Ed., K.CM.G. L.K.Q.CP.L, L.R.CS.I. L.R.CS. Ed. L.R.CP. et8. Ed.... F.R.CS. Ed. F.R.CS. Ed., L.R.CP. Ed. M.D. Edin., M.R.CS. Eng. M.B., B.S. Mell). ... M.D. Edin., L.R.C.S. Ed. M.B., CM. Edin. ... M.D. St. A., L.R.CP. et S. Ed. M.B., Ch. M. Aber. M.B. Dub., L.R.CS.L Carlton, Vic. Sydney, N.S.W. N^orthcote, Vic. Footscray, Vic. Richmond, Vic. Sydney, N.S.W. East Melbourne, Vic. Kew Asylum, Vic. Sydney, N.S.W. Sale, Vic. Dunedin, X.Z. Forbes, N.S.W. Mentone, Vic. New Norfolk, Tas. Fitzroy, Vic. Sandhur.st, Vic. New Guinea. Fitzroy, Vic. St. Kilda, Vic. Eaglehawk, Vic. Wodonga, Vic. Goulburn, N.S.W. Glanville, N.S.W. Melbourne, Vic. Sydney, N.S.W. WilIiam.stown, Vic. South Yarra, Vic. Sydney, N.S.W. Hawthorn, Vic. XX INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. JNIacMuUen, J. Carnegie MacNaniara, P. J. M'NisIi, J. MacRoberts, W. K. ... Macvean, P. INIacan.sli, W. Magill, M. Malier, W. Odillo Malioney, L. F. Mailer, M. Main, H. M alone J, W. E. N. . . Manning, Hon. F. N.... Mansou, J. F. W. Marano, G. Y. Marten, Pv. H. Martin, J. W. Mason, J. B. Massey, E. H. C. Maudsley, H. Maun.sell, H. W. Menzies, E. Meyer, F. Milford, F. Miller, J. J. Mitchell, H. St. J. Mitchell, J. Mitcliell, J. T. Mullisori, C. H. L.K.Q.C.P.L, L.R.aS.L L.R.C.S.I. M.D., T.C.D., L.R. C.S.I. M.B., L.K.Q.C.P.L... M.D. Glas., L.R.C.S. Ed. M.B., CM. Edin., ... L.E.C.P. et S. Ed. M.B., B S. Melb. ... M.D., Ch.M. Q.U.L, M.R.C.S. Eng. M.B. Durh., M.R.C.S. Eng. M.B., B.S. Melb. ... M.B., B.S. Melb. ... M.R.C.S. Eng. M.D. St. A., M.R.C.S. Eng. ... M.B., B.S. Melb. ... M.D. Nai>les M.B. Cantab., M.R.C.S. L.R.C.P. et S. Ed.... M.R.C.S. Eng., L.R.C.P. Ed. L.R.C.P. et S. Ed. ... M.D. Lond., M.R.C.P. Lond., M.R.C.S. Eng. M.B. Dub., M.R.C.S. Eng. M.R.C.S. Eng. M.B., B.S. Melb. ... M.D. Heidelberg, ... M.R.C.S. Eng. M.B., B.S. Melb. ... L.R.C.P. Ed., L.F.P.S.G. M.B., Ch. M. Aber. M.D., Ch. M. Aber., M.R.C.S. Eng. M.B., B.S. Melb., ... M.R.C.S. Enff. Melbourne, Vic. Warrnambool, Vic. Myall River, N.S.W. Newcastle, JS'.S.W. Wedderljurn, Vic. Brighton, Vic. Thargomiiidah. Q. Sydney, N.S.W. St. Kilda, Vic. Carlton, Vic. Mabnsbury, A'ic. Melbourne, Vic. Sydney, N.S.W. Mahasbury, Vic. Sydney, N.S.W. Adelaide, S.A. Ci-eswick, Vic. Longford, Tas. Daylesford, Vic. Melbourne, Vic. Dunedin, N.Z. Napier, N.Z. Carlton, Vic. Sydney, N.S.W. Melbourne, Vic. Kyneton, Vic. Narandera, N.S.W. Port Adelaide, S.A. Malvern, Vic. ROLL OF MKMBEHS. 3Ionoy, C. H. Moloney, P. Molyneux, J. F. Moore, G. Morgan, Cosby W. Moore, T. D. Moore, W. 3Ioore, W. F. Morgan, I). C. Morrison, A. Morrison, "W. Morton, F. W. W. Mueller, A. Mueller, Baron Sir F. von Mullen, W. L. Munro, A. Watson Muskett, P. E. Naylor, H. G. H. Neild, J. E. Nelly, F. J. Newman, F. J. New inarch, B. J. Nickoll, J. S. Nicoll, A. Nolan, L. A. Nonnan, W. Noriie, A. Noyes, A. W. F. Nutting, P. Nyulasy, F. A. O'Brien, J. A. O'Brien, J. W. Ochiltree. E. G. M.B., B.S. Melb. ... M.B. Melb. M.R.C.S. Eng., L.K.C.P. Ed. M.D. Syd., M.R.C.S. Eng. M.D. Brux., M.R.C.S. Eng. L.R.C.S.I. M.D., M.S. Melb. ... L.R.C.P. Ed. M.R.C.S. Eng., L.R.C.P. Ed. L.R.C.P. et S. Ed.... M.D., Ch.M. Glas.... L.R.C.P. etS. Ed.... M.D., Ch. D. Giessen M.D., Ph. D., F.R.S., K.C M.G. M.B., B.S. Melb. ... M.B., CM. Edin. ... L.R.C.P. etS. Ed.... L.R.C.P. et S.Ed. ... M.D., B.S. Melb. ... L.R.C.P. et S.Ed. ... M.B., B.S. Melb. ... M.R.C.S. Eng., L.R.C.P. Lond. M.R.C.S. Eng. M.B., Ch.M. Aber.... L.K.Q.C.P.I., L.R.C.S.L M.R.C.S. Eng., L.R.C.P. Ed. M.D., Ch.M. Aber. ... M.R.C.S. Eng. M.R.C.S. Eng., L.R.C.P. Lond. M.B., B.S. Melb. ... M.B., Ch.M. Glas.... M.B., Ch. B. Dub.,... F.R.C.S.L M.B., Ch.M. Glas., ... M.R.C.S. Eng. Prahran, Vic. Melbourne, Vic. Willianistown, Vic. St. Kilda, A^ie. Newcastle, N.S.W. Queenscliff, Vic. Melbourne, Vic. Strathalbyn, S.A. Bairnsdale, Vic. Melbourne, Vic. Ballarat, Vic. Fitzroy, Vic. Yackandandah, Vic. South Yarra. Vic. Kew, Vic. Sydney, N.S.W. Sydney, N.S.W. Launceston, Tas. Melbourne, Vic. Fitzroy, Vic. Geelong, Vic. Sydney, N.S.W. Hawthorn, Vic. Tambo, Q. Wari-agul, Vic. Adelaide, S.A. Sydney, N.S.W. Deniliquin, N.S.W. Caul field, Vic. Toorak, Vic. Sunbury, Vic. Carlton, Vic. Ballarat, Vic. INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. O'Connell, J. O'Donnell, N. M. O'Haia, H. M. O'Neill, G. J. L. Oram, A. Murray O'Sullivan, M. U. Owen, F. J. Owen, W. H. ' Palmer, G. Pardey, J. M. Park, J. H. Parkinson, C. J. Paterson, A. S. Peipers, F. Penfold, O. Pentland, A. Perceval, M. W. C. Pestell, J. Pettigrew, A. J. W Phelps, W. Pincott, R. Pinnock, R. D. Pockley, F. A. Pollen, H. Poulton, B. Powell, J. J- Power, R. Praagst, L. F. Prendergast, J. J. Quaife, F. H. Rabl, H. Radclitfe, H. H. Ralph, T. S. Rankin. W. B. L.R.C.P. et S. Ed. ... M.B., B.S. Mell.. ... L.R.C.S.I., L.K.Q.C.P.I. M.B., CM. Ediii. ... M.D., CM. Edin. ... L.R.C.P. et S. Ed. ... M.D., B.S. Melb. ... M.R.C.S. Eng., L.K.Q.C.P.I. M.B., B.S. Melb. ... M.B., B.S. Melb. ... L.R.C.P. Lond. ... M.B. Lond., M.R.C.S. Eng. M.D. Edin., L.R.C.S. Ed. M.D. Berlin. M.R.C.S. Eng. M.B.Dub.,L.R.C.S.L M.K.Q.C.P.L M.R.C.S. Eng. M.R.C.S. Eng. M.R.C.S. Eng. M.R.C.S. Eng. M.B., Ch.M. Glas. ... M.B., CM. Edin., ... M.R.C.S. Eng. M.D., M. Ch. Dub.... M.D., B.S. Melb M.R.C.S. Eng. M.D. Lond., M.R.C.S. Eng. L.R.C.P. Ed., L.R.CS.T. M.B., B.S. Melb. ... M.D. R.U.L, M.R.C.S. Eng. M.D., Ch.M. Glas.... M.D.Munich M.R.C.S. Eng. M.R.C.S. Eng. F.R.CS. Ed. Adelaide, S.A. Melbourne, Vic. Melbourne, Vic. Sydney, N.S.W. Sydney, N.S.W. Melbourne, Vic. Fitzroy, Vic. Melbourne, Vic. Ararat, Vic. Launceston, Tas. St. Mary's, Tas. Malvern, Vic. Adelaide, S.A. Hawthorn, Vic. Sandhurst, Vic. Jamestown, S.A. Mt. Bischoft; Tas. Kyneton, Vic. Camperdown, Vic. Melbourne, Vic. Geelong, Vic. Ballarat, Vic. Sydney, N.S.W. Gisborne, N.Z. Adelaide, S.A. England. St. Kilda,, \^ic. Melbourne, Vic. Mel])ourne, Vic. Sydney, K . S. W. Murtoa, ^'ic. Ballarat, ^'^ic. Carlton, Vic. St. Kilda, Vic ROLL OF MEMBERS. XXIH Ray, H. .. M.B., Ch. M. (ilas. ... L.R.C.S. Ed. Carlton, Vic. liees, J. .. M.R.C.S. Eng., L.R.C.R Ed. Hindmarsh, S.A. Reid, J. A. .. M.D., Oh. M. Aber. Sale, Vic. Reid, J. .. M.D., Ch. M. Aber. Melbourne, Vic. Reid, R. G. .. L.R.C.P. etS. Ed. ... Nagambie, Vic. Rendle, R. .. F.R.C.S. Eng. Brisbane, Q. Roberts, W. S. .. M.R.C.S. Eng. Dunedin, N.Z. Robertson, J. .. M.D. Aber., L.R.C.S. Ed. Melbourne, Vic. Robertson, J. A. .. M.B., Ch. M. Glas. East Melboui-ue, Vic Robertson, R. .. F.F.RS.G. Adelaide, S.A. Robertson, R. .. M.R.C.S. Eng. St. Kilda, Vic. Robertson, W. .. M.B., B.S. Melb. .. Adelaide, S.A. Rooke, C. .. F.R.C.S. Eng. Germanton, N.S.W. Rorke, C. .. L.K.Q.C.P.I. L.R.C.S.I. Sydney, N.S.W. Ross, C. .. M.B., CM. Edin. .. M.D. Syd. Sydney, N.S.W. Ross, E. F. ... M.D. Brux. M.R.C.S. Eng. Sydney, N.S.W. Ross, J. ... M.D. Wurz. Pyramid Hill, Vic. Roth, R. E. ... M.R.C.S. Eng. Sydney, N.S.W Rowan, T. .. M.D. Syd., F.R.C.S. Ed. Melbourne, Vic. Rudall, J. F. ... M.B., B.S. Melb. .. Melbourne, Vic. Rndall, J. T. ... F.R.C.S. Eng. Melbourne, Vic. Ruddle, R. G. ... M.D., B.S. Melb. ... Stawell, Vic. Rundle, G. E. ... F.R.C.S. Ed., L.R.C.P. Ed. Sydney, N.S.W Ryan, C. S. .. M.B., CM. Ed. Melbourne, Vic. Ryan, E. ... M.B., B.S. Melb. .. Nhill, Vic. Ryan, J. P. .. M.K.Q.C.P.I., L.R.CS.I. Melbourne, Vic. Ryan, M. J. ... M.B., B.S. Melb. .. Kyneton, Vic. Ryan, T. B. ... M.B., B.S. Melb. .. Clifton Hill, Vic. Salmon, H. R. ... M.B., B.S. Melh. ... Ballarat, Vic. Salter, A. E. ... M.B., B.S. Melb. .. Thursday Island, Q. Scantlebury, G. J. ... L.R.C.P. etS. Ed. .. Linton, Vic. Schleichei-, C. ... M.D. Wurz. Melbourne, Vic. Schlesinger, R, E. ... M.B., CM. Edin., .. M.R.C.S. Eng. St. Kilda, Vic. INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Scholes, R. B. Scot-Skirving, R. Scott, G. A. Scott, J. H. Scott, R. Scott, T. Scott, W. Seal, C. Service, J. Shields, A. Shewen, A. Sliownian, L. F. Shuter, C. Y. Simmons, E. L. Simons, C. W. Simpson, D. Sinclair, E. Singleton, F. E. Corbet Singleton, J. Sisca, N. Skinner, D. Smart, T. C. Smith, C. Smith, J. Govett Smith, P. Smith, S. Smith, S. Maberly Smith, W. Beattie Snowball, W. Spoof, Axel R. Springthorpe, J. W. Stacpoole, A. R. Siapleton, J. J. M.B., CM. Edin. M.B., CM. Edin. M.B., CM. Edin. M.D., CM. Edin., M.R.CS. Eng. M.B., Ch. M. Glas. M.R.CS. Eng., L.R.CP. Ed. M.R.CS. Eng. M.B. Melb. L.R.CP. et S. Ed. M.D. Edin. M.D. Lond., M.R.CS. Eng. L.R.CP. et S. Ed. M.B. Durh., M.R.CS. Eng. M.R.CS. Eng. L.R.CS.I. M.B., Ch. M. Glas. M.D., Ch. M. Glas. L.R.CP. et S. Ed. M.D. Glas. M.D. Naples M.B., Ch.M. Aber. F.R.CS. Ed. M.D. Lond., M.R.C.S. Eng. M.R.C.S. Eng. M.D. Syd. M.R.CS. Eng. M.R.CS. Eng., L.R.C.P. Ed F.R.CS. Ed., L.R.CP. Ed. M.B., B.S. Melb., L.R.CS. Ed. M.D., B.S. Melb., M.R.CP. Lond. L.R.C.P. et S. Ed. M.B., CM. Edin., M.R.CS. Encj. Brisbane, Q. Sydney, N.S.W. Mai'yborough , Vic. Dunedin, N.Z. Ballarat, Vic. Warrnambool, Vic. Elsternwick, Vic. Buninyong, Vic. Sydney, N.S.W. West Melbourne, Vic. Sydney, N.S.W. Ringwood, Vic. Creswick, Vic. St. Kilda, Vic. Brighton, Vic. Oakleigh, Vic. Sydney, N.S W. Melbourne, Vic. Melbourne, Vic. Hawthorn, Vic. Beechworth, Vic. Hobart, Tas. Casterton, Vic. Clarence R., X.S.W. Brisbane, Q. Kyneton, Vic. Geelong, Vic. Ararat, Vic. Carlton, Vic. Ab&, Finland Melbourne, Vic. Hawthorn, Vic. Lambton, N.S.W. ROLL OF MEMBERS. Stawell, R. R Steel, T. H. Steuhouse, W. M. Steven, A. Stewart, C. A. Stewart, D. E. Stewart, R. Stirling, E. C. Stirling, R. A. Stoker, H. Stuart, T. P. Anderson Stuart, W. Sweetnam, W. F. Syme, G. A. Syrae, W. H. Symons, M. J. Taaffe, O. G. Tanant, H. J. Taylor, Hon. W. F. . . . Thane, E. Thomas, J. Davies Thompson, J. Ashburton Thomson, J. R. M. ... Thomson, M. Barclay... Thwaites, J. S. Tilley, W. J. Toll, J. T. Travers, G. F. Tremearne, J. Trood, C. J. M.B., B.S. Melb. ... M.D. Glas., L.F.P.S.G. M.D., Ch. M. Glas. M.D., CM. Edin., ... M.R.C.S. Eng. L.R.C.P. etS. Ed.... M.B., C.M. Edin. ... M.D., B.S. Melb. ... M.D. Cantab., F.R.C.S. Eng. M.B., B.S. Melb., ... L.R.C.P. et S. Ed. L.R.C.S.I., L.K.Q.C.P.I. M.D., CM. Edin. ... M.D., Ch. M. Aber. M.D., Ch. M. Q.U.I. M.B., M.S. Melb., ... F.R.C.S. Eng. L.R.C.P. Lond., ... L.R.CS.I. M.D., C.M. Edin. L.R.C.P. et S. Ed.... L.R.CS.I., L.R.C.P. Ed. M.D. Qu. Coll. Kingston, M.R.C.S. Eng. M.B. Lond., M.R.C.S. M.D. Lond., F.R.C.S. Eng. ALR.C.S. Eng. M.B., B.S. Melb. ... M.D., CM. Edin. ... M.B., B.S. Melb. ... M.R.C.S. Eng. M.R.C.S. Eng., L.R.C.P. Ed. M.R.CS. Eng., L.R.CP. Lond. M.R.CS. Eng. M.B., B.S. Melb. ... Melbourne, Yio. Toorak, Vic. Dunedin, N.Z. Aulmrn, Vic. Melbourne, Vic. Brunswick, Vic. Hindmarsh, S. A. Adelaide, S.A. Melbourne, Vic. Wycheproof, Vic. Sydney, N.S.W. Brighton, Vic. Mortlake, Vic. Melbourne, Vic. Stawell, Vic. Adelaide, S.A. Rochester, Vic. Sydney, N.S.W. Brisbane, Q. Yass, N.S.W. Adelaide, S.A. Sydney, N.S.W. York,\v.A. South Yarra, Vic. Tallangatta, Vic. Warwick, Q. Port Adelaide, S.A. Hawksbuni, Vic. Creswick, Vic. Mooroopna, Vic. INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Turner, D. Twynani, G. E. Usher, J. E. Vassie, R. Vaughan, A. P. Vause, A. J. Verco, J. C. Verity, H. W. 8. Voss, F. H. V. Wall, Max. Walsh, W. B. Walter, J. B. Ward, R. D. Warren, R. B. Warren, W. E. Watkins, S. C. Watkins, W. L. Way, E. W. Waylen, A. R. Webb, J. H. Weber, J. A. Weigall, R. E. West, W. A. Whitcombe, W. P. Whittell, H. T. Whitton, T. B. Wigg, H. C. Wight, J. c. Wilkinson, A. M. L.R.C.P. Lend., L.R.aS. Ed. M.R.C.S. Eng., L.R.C.P. Lend. L.R.CP. Lend. Melbourne, Vic. .. Darlingliurst, N.S W. Toorak. Vic. M.B., B.S. Melb. ... M.B., CM. Edin. ... M.D. Lond., F.R.C.S. Eng. M.R.C.S. Eng. L.R.C.P. Ed. ... F.R.C.8. Eng. M.D. Munich M.D.Dub.,F.R.C.S.L M.D. Dub. M.R.C.S. Eng. F.R.C.S.L, L.K.Q.C.P.L M.D., Ch. M. Q.U.I. M.R.C.S. Eng. L.K.Q.C.P.L, L.R.C.S.L M.D. Edin., M.R.C.S. Eng. M.D. St. A., M.R.C.S. Eng. M.R.C.S. Eng.," ... L.R.C.P. Lond. M.D., Ch. D. Giessen. M.B., B.S. Melb. L.K.Q.C.P.L, L.R.C.S.L M.R.C.S. Eng. M.D. Aber., M.R.C.S. Eng. M.D. Q.U.L, L.R.C.S. Ed. M.D. Edin., F.R.C.S. Eng. M.B., B.S. Melb., M.R.C.S. Eng. M.B. Melb. Box Hill, Vic. Teuipe, N.S. W. Adelaide, S.A. Cheltenham, Vic. Rockhamj)ton, Q. Colac, Vic. Kew, Vic. Chiltern, Vic. Sydney, N.S.W. Camden, N.S.W. Sydney, N.S.W. Manly, N.S.W. Yarra Bend, Vic. Adelaide, S.A. Perth, W.A. Melbourne, Vic. Natimuk, Vic. Elsternwick, Vic. Sydney, N.S.W. Ballarat, Vic. Adelaide. S. A. Reefton, N.Z. Carlton, Vic. Balaclava, Vic. Mornington, Vic ROLL OF MRMBERS. XKVU Wilkinson, J. F. Wilkinson, W. Camac . Wilkinson, W. Clcland Williams, D. J. Williams, J. Williamson, W. Williamson, W. C. Willis, T. R. H. Willmott, J. J. E. Wilson, J. S. Wilson, J. T. Wolfenden, J. H. Wood, A. J. Wood, P. U. V^'ood, W. A. Woodward, G. P. M. Woinaiski, G. H. Zk- Woinarski, S. E. A. Zicliy Wooldridge, H. Woolley, G. T. Won-all, R. Wriglit, H. G. A. Youl, H. Young, J. M.B., B.S. Melb. M.D.Lond.,M.R.C.P Lond.,M.R.C.S.Eng M.B., Ch. B. Dub. .. M.D. Ht. A., F.R.C.S. Eng. M.D. Edin., M.R.C.S. Eng. M.D. Edin., L.R.C.8. Ed. M.D.,M.Cli.Q.U.r... M.B., B.S. Melb. .. M.D.,Ch.M, Aber.,.. M.R.C.S. Eng. M.D.,Ch. M. Glas.,.. M.B., CM. Edin. .. L.R.C.S.r., L.K.Q.C.P.I. M.D., B.S. Melb. .. M.R.C.S. Eng., L.R.C.P. Lond. M.B., B.S. Melb. .. M.D. Brux., F.R. C.S.I. M.B., B.S. Melb. .. M.B., B.S. Melb. .. F.R.C.S. Eng. M.R.C.S. Eng. M.D., Ch. M. Q.U.I. M.R.C.S. Eng. M.D. St. A.,^ M.R.C.S. Eng. M.D., Ch. M. Q.U.I. Bright, Vic. Sydney, N.S.W. Preston, X'u: Queensclif}", Vic. Melbourne, Yi(;. Ararat, Vic Parramatta, N.S.W. Daylesford, Vic. Melbourne, Vic. Wilcannia, N.S.W. Sydney, N.S.W. Dunolly, A'ic. Carlton, A'ic. Palmerston, Northern Territoiy. Malvern, Vic. Sydney, N.S.W. West Melbourne, Vic. Ballarat, Vic. South Yaira, Vic. Castlemaiiie, Vic. Sydney, N.S.W. Sydney, N.S.W^ Melbournt% Vic. Invercargill, N.Z. HONORARY MEMBERS. Blackett, C. R. ... Government ... Melbourne, Vic Analytical Chemist Bo.sisto, Hon. .). ... Chemist ... Richmond, Vic. Candler, C. ... Melljourne Club ... Melbourne, Vic. XXVni INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Melbourne, Vic. Ellery, R. L. J., F.R.S. Government Astronomer Hamlet, W. M. Hector, Sir James Hayter, H. H. Kernot, W. C. McCoy, R, F.R.8. Masson, D. Orme Newbery, Cosmo Spencer-, W. B. Government Analytical Chemist Government Statist President of the Royal Society of Victoria Professor of Natural Science Professor of Chemistry Director of the Tech- nological Museum Professor of Biology Sydney, N.S.W. New Zealand Melbourne, Vic. Melboui'ne, Vic. Melbourne, Vic. Melbourne, Vic. Melbourne, Vic. Melbourne, Vic. PilEFACE. The Literary Committee, in presenting to Members the Transactions of the Second Session of the Intercolonial Medical Congress of Australasia., regrets the delay that has occurred in publication. The success of the Session entailed difficulties through the mass of Papers submitted, and the consequent necessity for further financial arrangements. The Government of Victoria, with great liberalit}', increased the sum which had been granted to defray the cost of publica- tion. In view of the decision of the Committee to keep the Transactions within a definite limit, it was unavoidable that many Papers should be curtailed, and that others, to the regret of the Committee, should be held back in their entirety. In several instances, also, the rejiorts of discussions hav^e been compressed, or even omitted. In consequence of the great distances between the chief centres of population in Australasia, small delays frequently occurred while the requisite authors' corrections were being obtained, and in some cases these corrections could be dealt witli only in the column of errata. With these explanations, the Committee submits the result of its labours to the kindly judgment of the Members. By order of the Literary Committee, T. N. FITZCxERALD. Melbourne, 1889. President. CONTENTS. Inai GURAL Meeting Pkesident's Address. T. N. FitzGerald General Meetings, Keceptions, and Entertainments Section op Medicine — Puesident's Address. W. F. Taylor Some Notes on Disease in British New Guinea. Sir W. McGregor On Filaria. J. Bancroft . . Beri-beri as seen in the Northern Territory of South Australia P. M. Wood Diseases of Polynesians, as seen in Queensland. F. Bowe Malarial Fevers of Tropical Queensland. T. S. Dyson The Hepatic Element in Disease. J. W. Springthorpe Notes on Seven Cases of Typhlitis. A. S. Joske The Importance of the Constitutional Factor in Disease. J. Kobertson Phthisis in New Zealand. D- Colquhoun .. Treatment of Phthisis by Climate. D. Turner The Open-air Treatment of Phthisis. J. P. Ryan . . On Pneumatic Therapeutics, by means of the Portable Apparatus V. Marauo . . On the Immediate Treatment of Pleurisy with Eli'usion. S. D. Bird The Nervous Substratum of Influenza. J. W. Springthorpe . . On Want of Proportion in the Signs and Symptoms of Diseases of the Heart and Great Vessels. J. Jamieson .. .. A Case of Cerebellar Disease, in which an Exploratory Trepliining and Removal of Diseased Brain-substance was followed by Good Results H. Maudsley Cerebellar Disease. J. C. Verco . . A Case of Injury to the Frontal Region of the Brain. D. Colquhoun A Series of Cases Illustrating Localisation in Nervous Diseases J. W. Springthorpe . . . . . . . . . . A Case of Raynaud's Disease. D. Grant .. Aortic Incompetence and Locomotor Ataxia. D. Colquhoun .. Chnical Notes on some Cases of Cerebro-spinal Fever. W. Finlay On some Forms of Sunstroke Observed in Children. W. K. MacRoberts Typhoid Fever, General Meeting Concerning History of Typhoid Fever in Victoria, and Its Etiology. J. Robertson The Etiology of Typhoid. J. G. Carstairs . . Typhoid Fever Connected with Milk Supply. H. B. Allen Typhoid Fever, History of an Epidemic. A. V. Henderson .. A Note on the Incubation Period of Enteric Fever. J. C. Verco Notes on Typhoid Fever. J. W. Springthorpe Notes on Variations in the Pathological Process in Typhoil Ftver H.B.Allen The Cold Bath Treatment of Typhoid Fever. F. E. Hare Notes on Typhoid and its Treatment. F. H. Bonnefin Discussion on Typhoid .. .. .. .. .. 1 !) 21 3.5 46 49 54 59 64 67 71 73 79 87 90 93 99 101 106 113 117 117 121 129 135 139 144 149 149 155 159 169 172 173 175 179 185 188 I'AriE XXXU INTERCOLONIAL MEDICAL COXGUESS OF AUSTRALASIA. Section of Surgery — President's Address — Is Surgery a Science ? E. C. Stirling . . 197 Laparotomy, with Remarks on some of the Injuries and Diseases which may Render the Operation Necessary. Sydney Jones .. .. 216 Upon the Treatment of tlie so-called Tropical Abscess of the Liver, by Free Incision and Stitching of tlie Abscess-wall to the Lips of the Parietal Wound. J. Davies Thomas . . . . . . . . 230 Congenital Phimosis and Adherent Prepuce. Gr. T. Woolley . . . . 234 Resection of the Intestine by a New Method. H. W. Maunsell . . 236 Critical Review of the Results of Excision of Hard Chancre. M. Crivelli 241 Observations on the Practice of Cystotomy. A. MacCormick . . 246 Supra-pubic Lithotomy. J. Tremearne . . . . . . . . 257 Twenty Successful Cases of Supra-pubic Lithotomy. H. O'Hara . . 260 Notes on Lateral Spinal Curvature, with Special Reference to Treatment. G. A. Scott . . . . . . . . . . . . . . 264 The Management of Traumatic Head Cases, with a view to the Prophylaxis of Immediate and Remote Morbid Sequela?. A. J. W. Pettigrew . . . , . . . . . . . . . . 269 The Treatment of the Sac in Herniotomy. K. R. Kirtikar . . . . 271 A Case of Diffuse Suppurative Periostitis of the Tibia, terminating in Recovery almost without Necrosis. J. C. Verco .. .. 277 Abscess in the Left Middle Cerebral Lobe — Evacuation by Operation — Temporary Improvement — Death. J. C. Verco and E. C. Stirling 280 A Few Observations on some Cases of Cancer of the Breast, with a Table of Forty-seven Cases. F. Milford . . . . . . 288 On the Use of Special Exercises and of Active and Passive Movements, as an Aid to Surgical Treatment. R. E. Roth . . . . . . 298 An Instrument for Accurately Recording Lateral Curvature of the Spine. R. E. Roth .. .. .. .. .. .. .. 299 Case of Compound Dislocation of tlie Ankle-joint, with Fracture of Astragalus j;c/- ae and Resection of Same. H. C. Garde . . . . 300 A Case of Loreta's Operation for Dilatation of the Pyloric Orifice of the Stomach. W.Gardner .. .. .. .. .. 301 The Surgery of the Kidney, W. Gardner , . . . . . . . 305 A New Procedure for the Cure of Congenital Talipes Varus and Equino- varus. T. N. FitzGerald .. .. .. .. ..316 Subcutaneous Drilling in the Treatment of Bone Inflammation. T, N. FitzGerald . . . . . . . . . . . . . . 321 A Case of Cleft Palate. T. N. FitzGerald . . . . . . , . 326 Hydatid Disease, General Meeting Concerning .. .. .. 328 The Geographical Distribution of Echinococcus Disease. .). Davies Thomas .. .. .. .. .. .. ..328 Age in Relation to Hydatid Disease. J. Davies Thomas . . . . 342 Sex in Relation to Hydatid Disease. J. Davies Thomas . . . . 343 The Surgical Treatment of Hydatid Disease, W. Gardner . . . . ♦ 345 The Operative Treatment of Echinococcus Disease. J. Davies Thomas 352 Hydatid of the Brain — Removal by Operation — Death after Four Days. J. C. Verco . . . . . . . . . . . . . . 377 Notes of a Case of Hydatid Cyst of the Zygomatic Fossa. J. R. M. Thomson .. .. .. .. .. .. ..385 Case of Multiple Hydatid Cysts Treated by Thoracic Incisions — Recovery. J. C. Verco and A. A. Lendon . . . . . . . . 388 CONTENTS. XXXlll Hydatid Disease (Continued) — pack Treatment of Hydatid Disease by Injection of Permanganate of Potass. W. P. Whitcombe . . . . . . . . . . . . 389 Upon tbe occasional presence of Bilirubin in Hydatid Cysts. J. Davies Thomas .. .. .. .. .. .. ..390 Discussion on Hydatid Disease . . . . . . . . 392 Section oe Hygiene, Forensic and State Medicine — President's Address — Comparative View of the Mortality of the Different Colonies from Certain Diseases. H. N. MacLattrin 401 A Record of the Present Sanitary State of New South Wales. J. Ashburton Thompson . . . . . . . . . . 434 State Medicine in New South Wales, with some Remarks on the Medical Acts of the Colony. C.W.Morgan .. .. .. . . 45& Hygienic Conditions in Victoria. J. W. Springthorpe . . . . 465 The Sanitary Condition of New Zealand. Leger Erson . . . . 485 State Medicine in Western Australia. J. R. M. Thomson . . . . 489 Sewage Disposal. W. F. Taylor . . . . . . . . . . 490 Leprosy in its Relation to the European Population of Australia. J. M. Creed . . . . . . . . . . . . 499 Short Account of the Climatology of Nelson, New Zealand, and the diseases for which it is most suited. J. Hudson . . . . 504 The Colonies as a Health Resort for Consumptives. J. Carnegie MacMullen .. .. .. .. .. ..509 Some Observations on the Westerly Winds of Winter in their influence on disease. F. Milford . . . . . . . . . . 512 Should the Medical Practitioner be an Officer of the State ? .J. T. Mitchell 515 Anthrax in Australia, with some Account of Pasteur's Method of Vaccination — Demonstration at Junee, N.S.W. W.M.Hamlet .. 522 A Note on Pasteur's Methods. M. Crivelli . . . . . . . . 535 Is Cholera Quarantine Scientifically Sanctioned ? K. R. Kirtikar . . 539 The Necessity of Federal Inspection of Foreign-going Ships Arriving at Australian Ports, coupled with Isolating and Federal Quarantine Laws. A.E.Salter .. .. .. .. .. 545 The Evils of Specialism. D. Turner . . . . . . . . 551 Hygienic Conditions of Abo, Finland. Axel R. Spoof . . . . 554 Some Remarks on the principles and practice of Ventilation for Cold and Warm Climates. W. V. Jakins . . . . . . . . 558 What becomes of the Typhoid Germ in Sewage Farms ? A. Shields . . 562 Sectional Meetings and Abstract of Discussions . . . . 565 Section of Anatomy and Physiology — President's Address. T. P. Anderson Stuart . . . . . . 569 Demonstrations and Exhibits. T. P. Anderson Stuart . . . . 585 The Nature of Vision in Animals. J. W. Barrett . . . . . . 588 Section of Pathology — President's Address. W. C.\mac Wilkinson . . . . . . 591 The Pathology and Clinical Significance of an Excess of Indican in the Urine. R. H. Marten .. .. .. .. ..611 Unilateral Renal Atrophy, with Cases. T.C.Fisher -.. .. 615 The Microbe of Gonorrhcea. M. Crivelli . . . . . . . . 620 Section of Obstetrics and Gyn.sicology — President's Address. F. C. Batchelor . . . . . . . . 625 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Section of Obsteteics and Gyn.5;cology (Contimwd) — Pregnancy in its Various Stages, complicated by or associated with Ovarian Disease. T. Rowan . . Pifty Cases of Abdominal Section. F. C. Batchelor Two Cases of Extra-uterine Pregnancy, successfully treated by Abdominal Section. E. Worrall Conditions Warranting the Removal of the Ovaries and Tubes W. Balls-Headley Twisting of Pedicle in Ovarian Tumours. W. Gardner Puerperal Hysterectomy, or Porro's Operation by a New Method H. W. Maunsell Discussion Should a Medical Man Practise Midwifery, while in charge of a case of Puerperal Fever. J. C. Verco Some Remarks on the Administration of Ana?sthetics during Labour' S. Maberly Smith Discussion A Case of Uterine Pregnancy Supervening on Ectopic Gestation, which had Persisted Four Years. T. Chambers A Modification of Marion Sims' Operation for Metrotomy. G. R. Adam The Menstrual Function, its Inception, Duration and Cessation, Comparatively Considered. E. W. Anderson Pilocarpine in Puerperal Eclampsia. R. H. J. Fetherston The Obligations of Gynecology to Obstetrics. Felix Meyer . . Electricity in Diseases of Women. J. Foreman Section fob Diseases of the Eye, Eae and Throat — President's Address. M. J. Symons On Convergence. M. J. Symons . . A series of cases of Resection of the Optic and Ciliary Nerves. H. Lindo Ferguson Sandy Blight and Granular Ophthalmia. T. Aubrey Bowen . . Granular Conjunctivitis. R. B. Duncan A case of Sarcoma of the Eyelids. W. OdUlo Maher Remarks on Ojihthalmic Work in Western Australia. J. W. Hope The treatment of Chronic Catarrh of the Middle Ear. .J. W. Barrett Notes on a case of Optic Neuritis, following exposure to heat. H. Lindo Ferguson A case of Cerebellar Abscess, unsuccessfully treated by trephining. H Lindo Ferguson A case of Congenital Cyst of the Lower Lid, with Microphthalmos. W Odillo Maher A case of Glaucoma, in which Iridectomy appeared to be hurtful. J. T Rudall Death from Septic Meningitis, following excision of a suppurating eyeball J. T. ilutiall The Ocuiar Manifestations of late Hereditary Syphilis. G. Adliugton Sym.. On the 1 1 alment of Inlierited Specific Keratitis. J. Jackson . . On the liaii^'tr of operating on Eyes in which Mucoceles co-exist. J. W Bant; Ocular •• |)tnms due to Diseases of the Nasal Cavities. T. K. Hamilton I CONTENTS. XXXV Skotion ¥Qii Diseases of the Eye, Eak and Throat C Conthnted) — rAt:e A case of Double Glaucoma Fiilminans. Guido Thon .. .. 781 Post-nasal Growths. T. K. Hamilton . . . . . . . . 782 Aural Disease and Epilepsy. C. L. M. Iredell . . . . . . 789 The value of Redness of the Handle of the Malleus as a symptom in diseases of the Middle Ear. J. W. Barrett . . . . . . 704 Phlyctenular Conjunctivitis in Erythema Nodosum. L. W. Bickle . . 79() Exhibits. H. Lindo Ferguson .. .. .. .. .. 797 Nasal Calculus from a girl aged ten years. C. Morton Anderson . . 797 Microscopic Specimens of Glioma of the Retina. C Morton Anderson 798 Diphtheria — On the Nature and Causes of Diphtheria, and its Pielation to Croup. J. Jamieson . . . . . . . . . . . . . . SOU Notes on Diphtheria. A. Jarvie Hood . . . . . . . . 807 Discussion on Diphtheria . . . . , . . . . . 814 Section of Psychology — President's Address. F. N. Manning . . . . . . . . 816 A case of Sporadic Cretinism, with remarks. F. N. Manning . . . . 834 A contribution to the Study of Sporadic Cretinism — Six cases occurring in South Australia. E. C. Stirling .. .. .. .. 840 Race and Insanity in New South Wales. Chisholm Ross . . . . 849 Insanity in Australian Aborigines, with a brief analysis of thirty-two cases. F. N. Manning .. .. .. .. .. 857 Inebriety — its Etiology and Treatment. Patrick Smith . . . . 860 A Contribution to the Study of Inebriety. C. McCarthy . . . . 867 Australian Lunatic Asylums — Remarks on their Economic Management in the future. W. L. Cleland . . . . . . . . . . 870 Lunacj' Legislation in the Australian Colonies. W. Armstrong . . 877 The Training of Nurses and Attendants in Hospitals for the Insane. W. C. Williamson . . . . . . , , . . . . 887 The Extension of Hospital Methods to Asylum Practice. Eric Sinclair 895 The Housing of the Insane in Victoria, with special relation to the boarding-out system of treatment W. Beattie Smith .. .. 898 Section of Pharmacology — President's Address. Baron Sir F. von Mueller . . . . 909 On the Materia Medica and Pharmacology of Queensland Plants. T. L. Bancroft .. .. .. .. .. .. ..927 Notes on the Poisonous Action of Species of Gastrolobium and Oxylobium. J. C. Rosselloty . . . . . . . . . . . . 931 Bismuth : A Consideration of its probable Therapeutic Position. T. Dixson .. .. .. .. .. ,. ..933 A Note on Drumine : Is there such a body '? T. Dixson . . . . 937 On the Dosage of Iodide of Potassium, with especial reference to the treatment of psoriasis. W. M. Steuhouse . . . , . . 938 Some Evidence on the Efficacy of Chiau Turpentine in Cancer. H. E. Astles .. . .. .. .. .. ..941 Notes on the External Use of Sulphate of Iron. Colin Henderson . . 943 Notes on two cases of Snake-bite. J. S. Thwaites . . . . . . 945 Notes on some Indian Drugs, with Exhibits. K. R. Kirtikar . . . . 946 Notes on an Exhibit of Indian Remedies. R. Temple Wright.. .. 956 On a New Mode of Administering the Protoxide of Iron. T. S. Ralph 958 XXXvi INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Section for Diseases of the Skin — President's Address. J. P. Kyan Notes on the Treatment of some of the more frequently met with Sk: Diseases. E. L. Faithfiill Kotes of a fatal case of Pemphigus. A. A. Lendon . . A note on the New Zealand Birch Itch. D. Colquliouu On some cases of Alopecia Areata and its probable causes. D. Colquhouii Notes on some Skin Affections complicating Urethritis. E. A. Stirling Notes on a Case of Leprosy. F. Peipers A case of Ichthyosis. J. P. Eyan . . Section for Diseases of Children — President's Address — On Intestinal Troubles in Children. W. Snowball . . Gastro-enteritis in Children — some points in Pathology and Therapeutics. D. Collingwood Discussion on Gastro-enteritis An anomalous case of Acquired Infantile Syj^hilis. E. A. Stirling On a case of Syphilitic Dactyhtis in a Child. E. A. Stirling . . On a ease of Acquired Syphilis in a Child three years old. J. P. Eyan. . The Correlation of Follicular Tonsillitis in Children with other Zymotic Diseases. A. Honman Pathological Museum — Catalogue of Specimens submitted by Professor Allen Specimens of Hydatid Disease Appendix — Antiseptic Surgery and some of its results. E. B. Duncan PAGE 961 965 967 970 972 974 976 977 981 984 990 991 992 994 995 999 1004 1009' CORRIGENDA ET ADDENDA. Page xiii. After " Dawson," insert " Eankine, M.D." „ XV. After '• Gibson," insert " M.D., CM. Edin. ; Windsor, N.S.W." ,, xvii. For " Irving, J. A.," read " Irwin, J. A." „ xviii. After "Lawrence," insert " M.E.C.S. Eng., L.E.C.P. Lond." ,, xix. In the eleventh line from the bottom, read " Glanville, S.A." ,, xxiv. " Simons, C. W.," should read " Simons, C. N." ,, xxvi. " West, R. A.," should read " West, W. A." ,, 78. In the lifth line from the bottom, read " is said." ,, 193. In lines 32 and 35, for " Chamberlain," read " Chamberland." ,, 435. In line 26, for " suburban," read " urban." ,, 437. In the fifth line from the bottom, omit the words "on the Health Officer." „ 440. In the last column of both tables, after " Total," read " at all ages." „ 441. Line 24, after the words "and five miles long," insert " and by a 6 ft. wrought-iron pipe, a further distance of five miles." ,, 442. Line 25, for " a rate which is 8d. in the £," read " a sliding scale, the maximum charge being 6d. in the £." ,, 449. In the eleventh line from the bottom, for " coroner's," read " coroners." ,, 455. In column 2, line 1, for " 423,403," read " 423,493 ; " and in line 3, for " 952,524," read " 452,524." ,, 497. In line 32, for " Croyden," read " Croydon." ,, 503. Line 7, for " Hawaia," read " Hawaii." ,, 589. In line 21, for " 3-58," read " 4-54 ; " and in line 23, for " 4-54," read "5-85." „ 636. In the third line from the bottom, for " symtoms," read " symptoms." „ 776. Inlinel6, for " V12,"read" VR." INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. SIECOI^ID SESSIOIT. INAUGURAL MEETING. MONDAY, JANUARY 7, 1889. The Second Session of the Intei'colonial Medical Congi'ess of Australasia was inaugurated in the Wilson Hall, University of IMelbourne, on Monday, January 7, 1889. His Excellency Sir Henry Brougham Loch, G.C.M.G., K.C.B., Governor of the Colony of Victoria, with Lady Loch and suite, arrived at 11.30 a.m., and was received and escorted to the dais by the President and the Members of the Reception and Organisation Committees. On the dais, which was decorated with plants from the Botanic Gardens, and flowers from the gardens of the Parliament Houses, were seated the Honourable Duncan Gillies (Premier of Victoria), Sir Henry Parkes (Premier of New South Wales) and the Misses Parkes, Mrs. T. N. FitzGerald, the Bishop of iMelbourne and Mrs. Goe, His Honour the Chief Justice and Mrs. Higinbotham, Sir James MacBain (President of the Legislative Council) and Lady MacBain, Mr. M. H. Davies (Speaker of the Legislative Assembly) and Mrs. Davies, the Chancellor of the University of Melbourne and Mrs. Bi'ownless, Colonel Sargood (Executive Vice- President of the Centennial International Exhibition) and IMrs. Sargood, Dr. Verco (President of the First Session of the Congress), Colonel Brownrrgg (Commandant of the Victorian Military Forces) and Mrs. Brownrigg, the Right Worshipful the Mayor of Melbourne (Alderman B. Benjamin) and Mrs. Benjamin, Sir H. Wrenfordsley, Q.C., Dr. Kirtikar (of Bombay), Baron F. von Mueller, K.C.M.G., Professor McCoy, F.R.S., Professor Kernot (President of tlie Royal Society of Victoria), the AVarden of the Senate of the University and Mrs. Topp, and other distinguished guests. The Members of Congress were seated in front of the dais, and the I'emainder of the hall was well filled with visitors. The President (Mr. T. N. FitzGerald) took the chair, and invited His Excellency the Governor to formally open the Congress. I INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. THE GOVERNOR'S ADDRESS. His Excellency the Governor was enthusiastically received. He said : — Mr. President and Gentlemen, — Your meeting here in Congress is one of the most important of the many very interesting events that will make this period memorable in the history of Austi'alasia. The result of this Congress will be, I venture to believe, as greatly to the advantage of medical science throughout Europe and America, as it will be productive of great good in the country in which it has assembled. Eminent medical gentlemen have come from India and distant countries, as well as from all parts of Australia, to take pai't in the deliberations of this meeting ; men whose reputation as medical scientists will give to the papers which they will submit to the Congress a position of commanding influence upon some of the greatest medical questions of the day. The range of work that comes within the compass of medical science is so vast that no one mind can grasp and treat in an exhaustive manner the several branches in all their varied bearings ; while, in the busy walk of practical life, few medical men can aftbrd the time requisite for a close examination of more than one or two subjects of special study. These meetings are therefore of untold value, where the mental wealth acquired by individual scientists is collectively submitted to the critical analysis of their fellow workers, whose education, experienced observation and general knowledge properly fit them to discuss, consider, and estimate at their proper value the deductions that may with safety be drawn from the careful investiga- tion of the specialist. The amount of woi'k which the preparation for a meeting of this character entails can only be adequately appreciated when we reflect that the papers to be read are the outcome of years of unremitting study and obsei'vation, devoted to the successful attainment of the noblest end to which the greatest intellects can be applied — the amelioration of huiiian suffering in all its varieties and forms of miseiy — and tlius indirectly, to the strengthening and development of the brain power of the world, on which the ever-growing requirements of the day make an ever-increasing demand. It is perhaps a fitting close to the rejoicings with which the com- pletion of the Centennial of Australasia lias been commemorated, that this Congress should be now assembled in Melbourne. The past hundred years are replete with liistoric events which have created a British empire in the southern hemispliere ; but marvellous as has been the progress which has led to this develoj^ment, it is not so marvellous fiOVKRNOR S ADDRESS. 3 ns tlie advance that has been made during tlie same period in tlie knowledge and application of inedical science ; and if the experience of the past hundred years may be accepted as being any guide as to what the discoveries may be in the future, then those who may hope to live for the next thirty or forty years may revel in intellectual anticipations as to what they may then know and witness. "While the principal objects for which the Medical Congress has assembled will, without doubt, receive every consideration and be kept carefully in view, I trust the members of the Congress will likewise accept my assurance that it is our anxious desire to ofter to all our most cordial welcome, whether they come from distant lands, from the sister colonies, or from our own country districts, as also to those whose familiar faces we gladly recognise as belonging to our own immediate neighbourhood ; and I venture to submit as my personal medical contribution for the consideration of this great Congress, the pro- position, which I trust may be carried without a dissentient voice, that health is largely promoted by a well-projoortioned amount of relaxation and enjoyment of this world's pleasures, and I ain not sure whether the rule advocated in this colony, eight hours' work, eight hours' sleep, eight hours' play, should not be adopted by this Congress as the great panacea against all ills. I trust I may be permitted to congratulate Mr. FitzGerald, whose untiring efforts have in so large a measure contributed to bringing together so many eminent gentlemen, upon what I may safely, in anticipation, call this very sviccessful meeting of the Medical Congress ; and I congratulate myself upon its being one of the happy incidents connected with the ]30sition I have the honour to occupy in this colony, that I am permitted to be so far connected with this great and important meeting as to have been requested to perform the duty of declaring the Medical Congress open — a duty which I have now the honour to fulfil, with the most sincere and heartfelt good wishes that the result of its deliberations may tend to the advancement of science and to the benetit of mankind. The President then called upon the General Secretary, Professor Allen, to read the Report of the Executive Committee. Professor Allen accordingly read the following report : — REPORT OF THE EXECUTIVE COMMITTEE. May it please Your Excellency, Mr. President, Members of THE Congress, Ladies and Gentlemen, — At the close of the First Session of tlie Intercolonial Medical Congress of Australasia, held in Adelaide in August and September 1887, it was unanimously resolved that the Second Session should be held in B 2 4: INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Melbourne in 1890, or at such earlier time as the Medical Societies of Victoria might determine, and Mr. T. K. FitzGerald was elected President of the Session. Professor Allen undertook to bring the question of date and other necessary inatter.s before the IMedical Associations of Victoria. Accordingly, he submitted tlie following l>roposition to the four Associations : — " That the Medical Societie.s of Victoria empower a Provisional Committee to fix the date of the next Session of the Intercolonial Medical Congress of Australasia, and to make all iieedful arrangements for such Session until a general meeting of enrolled members can be held, at which a Progress Report shall be submitted, such Provisional Committee to consist of tlie President-Elect, six representatives chosen by the Medical Society of Victoria, six by the Victorian Branch of the British Medical Association, three by the Ballarat District Medical Society, and three by the Bendigo Medical Society, the Committee having power to add to its numbei', five members forming a quorum." The Associations approved this proposal, and representatives were appointed as follow : — By the Medical Society of Victoria — Professor Allen, Dr. J. Jackson, JNIr. E. M. James, Dr. Jamieson, Dr. Neild, and Dr. J. Williams ; by the A^ictorian Branch of the British Medical Association — Dr. Cutts, Dr. Graham, Dr. Henry, Dr. Ptowan, Mr. Rudall, and Dr. Springthorpe ; by the Ballarat District IMedical Society — Mr. Radcliffe, Mr. Tremearne, and Mr. Whitcombe ; by the Bendigo Medical Society — Dr. Hincheliff', Mr. MacGillivray, and Mr. Penfold. The Provisional Committee, thus constituted, met for the first time on December 6, 1887, when Dr. Graham w^as elected Honorary Treasurer, and Professor Allen Honorary Secretary ; Dr. J. W. Barrett and Mr. G. A, Syme Avere afterwards appointed Associate Secretaries. The terms of membership were defined, and a guarantee fund was created to cover any possible re.sidual liabilities. Rules of procedure were adopted, and it was determined to exercise largely the power given to the Committee of adding to its number. In this way the Committee came to consist of 87 members, representing very fully, not only the Societies, but also the whole profession throughout Victoria. It was finally resolved that the Congress should assemble on Monday, January 7, 1889, and should rise on Saturday, January 12. On April 5, 1888, a circular was address(Kl to members of the profession throughout Australasia. Over two thousand copies were despatched. The response was so satisfactory that on May 10 it was j)ossible to hold the first meeting of enrolled members. The Provisional Committee was then converted into the General Executive of the Conr^ress. A Special Organisation Committee was created, with power to determine the division of the Congress into Sections, to appoint the REPORT OF THE EXECUTIVE COMMITTEE. 5 officers of the Sections, and to perforoi all other acts necessary for the organisation of the Congress, reporting from time to time to the General Executive. This Organisation Committee consisted of tlie President, Dr. A. C. Brownless, Dr. Graham, Mr. E. M. James, Dr. Jamieson, Dr. Moloney, Dr. McCrea, Dr. Neild, Dr. James Robertson, Mr. Rudall, Dr. J. Williams, and the Secretary. A Eecei)tion Committee was then appointed to make provision for the housing of the Congress and its Sections, and for the reception and entertainment of visitors. This Committee consisted of the President, Dr. Balls-Headley, Dr. Brownless, Mr. F. T. West Ford, Mr. E. M. James, Dr. Moloney, Dr. C. S. Eyan, Dr. You), and the Secre- tary. Their Excellencies the Governors of all the Colonies kindly consented to act as Patrons of the Congress, and expressed their interest in its l)roceedings. His Excellency Sir Henry Loch, Governor of Victoria, graciously promised to render his invaluable assistance in promoting the success of the Congress, and in giving honourable reception to the members. The Executive Committee deplores the subsequent removal by death of Sir Anthony Musgrave, the late Governor of Queensland, who had wi-itteu in the kindest manner about the prospects and work of the Congress. The Honourable Duncan Gillies, Premier of the Colony of Victoria, kindly stated that the Government would do everything in its power to aid the Congress and to assist in the entertainment of members, and at his instance the Parliament voted a sum of money to cover the cost of printing the Transactions. The Presidents of all the Medical Associations of Australasia accepted office as Vice-Presidents of the Congress ; and with them were associated Di'. Verco, who so honourably discharged the office of President in the First Session ; Dr. Sydney Jones and Dr. Creed, of Sydney ; Dr. Cosby Morgan, of Newcastle ; Dr. Garde, of Maryborough, Queensland ; and Dr. Smart, of Hobart. The University buildings, including the Wilson Hall, were offered for the meetings of the Congress, at the instance of the Chancellor, Dr. Brownless, and this ofier was gratefully accepted. After much consideration, it was determined that the Congress should be divided into nine Sections, namely : — (1) Medicine, (2) Surgery, (3) Hygiene, Forensic and State Medicine, (4) Anatomy and Physiology, (5) Pathology, (6) Obstetrics and Gynaecology, (7) Diseases of the Eye, Ear, and Throat, (8) Psychological Medicine, (9) Pharmacology. Two sub-sections were provisionall}" constituted for Diseases of the Skin and Diseases of Children. These were subsequently converted into Sections. A President, Vice-Presidents, and a Secretary Avere b INTERCOLONIAL MEDICAL COXORESS OF AUSTRALASIA. appointed for each Section, The Presidents and Vice-Presidents were chosen from among the most eminent members of the Profession outside Victoria, the only exception being that Baron F. von Mueller, K.C.M.G.,at the repeated request of the Organisation Committee, accepted the Presidency of the Section of Pharmacology. The Secretaries of Sec- tions, for reasons which are obvious, were selected from among the members of the Profession in Victoria. Local Secretaries were appointed for the sevei'al Colonies, as follow : — for New South Wales, Dr. Muskett ; for Queensland, Dr. Hare ; for South Australia, Dr. Poulton ; for New Zealand, Dr. Closs ; for Tasmania, Dr. Pardey ; for Western Australia, Dr. Thomson. The Executive Committee desires to acknowledge how much the exertions of the Local Secretaries have contributed to the success of the Congress. Progress having thus been made, a final circular was issued to members of the Profession on July 8tli, showing in detail the organisation of the sections. Of this circular, two thousand two hundred and fifty copies were distributed. Communications were addressed to the leading Medical Journals throughout the United Kingdom, France, Germany, the United States, and Canada ; and through the kindness of the Surgeon-General at Calcutta, Sir Benjamin Simpson, and his Secretary, Dr. Bomford, circulars were distributed among members of the Medical Staff in the Presidencies of India. The Executive Committee desires to acknowledge the kind spirit which has characterised the notices of the Congress that :)ppeared in the British and Foreign Medical Press. At the instance of the Honourable the Premier of Victoria, the railway departments of various Colonies undertook to grant tickets at special rates to members of Congress travelling to Melboui-ne. The principal shipping companies also agreed to make concessions in favour of members en route to the Congress. For all these acts of courtesy, the Executive Committee now return its grateful thanks. Concernijig the work of the Congress, it was at an early stage determined that the President of each Section should deliver an Address, and that such arrangements should be made as to permit all members of Congress to listen to these Addresses. The Executive Committee believes that these Addresses alone would be ample justification for the assemljling of members. But, in addition, two important General Meetings will be held, one for the discussion of Hydatid Disease, the other for the consideration of the varied questions relating to Typhoid Fever. Three afterno(ms will be devoted wholly to Sectional Meetings; and the Executive Committee de.sires to express its regret that com- paratively little time is available in which to submit so many valuable papers. REPORT OF THE EXECUTIVE COMMITTEE. 7 A full pio^ramnie of the Pfoceedings of the Congress has been printed, in which will also he found a sketch of the University Buildings, showing the rooms iu which the Sections will meet. Con- venient passes for members' use have been })re[)are(l. The Secretary will be glad to sup[)ly programmes and passes to an}' members who have not yet received them. Special Demonstrations will be given in the various Hospitals, and in the Pathological ^luseum at the Medical School. For the accomplishment of the work of the Congress, it is essential that meetings should be held both in the mornings and the afternoons. In order to avoid inconvenience, one of the large rooms of the University has been set apart in which lunch will be provided on Tuesday, Wednesday, Thursday and Friday. The Executive Connnittee trusts that as many members as possible will avail themselves of the opportunity so afforded for social intercourse. For the full recording of the proceedings at the general meetings of the Congress, the Honourable the Premier has kindly arranged that Government Shorthand Writers shall be in attendance ; and the Executive Committee gratefully acknowledges the assistance thus given. It was resolved by the Executive that medical students in academic dress should be admitted to the meetings of the Congress. The Executive Committee recognises with heartfelt thanks the assistance given by the leailers of social life in Melbourne, in fitly entertaining the Members of the Congress. At tlie close of this meeting, the Right Worshipful the Mayor of Melbourne, Alderman Benjamin, will receive Members at the Town Hall, and will entertain them at luncheon. On Tuesday evening, the President of the Congress reqitests the honour of the company of Members at dinner at the Town Hall. On Wednesday evening. His Excellency the Governor and Lady Loch will receive the Members of Congress at Government House. On Thursday evening, the Honourable the Speaker of the Legislative Assembly, Mr. M. H. Davies, has invited the Members of Congress to meet the Members of Parliament at dinner in the Town Hall. On Friday evening, the President of the International Exhibition, Sir Jameis MacBain, and the Executive Commissioners, have invited ^lembers to attend a Special Concert at the Exhibition. (.»n Saturday, Sir William and Lady Clarke will entertain Members at a Garden Party at Ptupertswood. On the following Monday, the Honourable the Premier, Mr. Gillies, and the Government of Victoria, have invited ^Members to an excursion by sea to Port Phillip Heads. The Metropolitan Liedertafel has resolved to invite the members of Congress to a smoke- night concert in the upper hall of the Athemeum, on Monday evening, the Uth inst. 8 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. The Yorick Club has, with great courtesy, adniitted the Members of the Congress to the privileges of Honorary Membership. The Eight Worshipful the Mayor of Melbourne has placed at the disposal of members a room in the Town Hall, namely room five on the second floor, where one of the Congress attendants will at all times be on duty. Letters and parcels may be sent to this room. For the decoration of the Wilson Hall at this Inaugural Meeting, the Congress is in large part indebted to the Hon. the Minister of Lands, and under his instructions to Mr. Guilfoyle, the Curator of the Botanic Gardens. The Executive Committee desires to acknowledge the assistance which it has received from the Clerk of the Legislative Assembly, G. H. Jenkins, Esq. ; the Town Clerk of the City of Melliourne, E. G. Fitz- gibbon, Esq. ; and from the Registrar of the Melbourne University, E. F. A'Beckett, Esq., and the members of his staff". It remains only to record that the total number of members of tlie Congress is 653, of whom 13 are honorary members. Of the ordinary members 339 come from Victoria, 95 from New South Wales, 40 from South Australia, 24 from New Zealand, 16 from Queensland, 11 from Tasmania, 5 from Western Australia, 1 from the Northern Territory, 1 from New Guinea, 5 from England, 1 from India, 1 fi'om the Dutch Indies, and 1 from Finland. Dr. Yerco (Adelaide) moved the adoption of the report. The Executive Committee was to be congratulated on having brought the preliminary arrangements in connection with the Congress to such a satisfactory issue. The Programme of the Proceedings indicated the amount of work members of the Congi'ess had been stimulated to do, and the formidable list of socialities which it included showed the interest that had been excited in the non-professional section of the community. The inauguration of the Second Session gave hope of the firm establishment of the Intercolonial Medical Congress as a permanent institution. Dr. Batch ELOR (Dunedin) seconded the motion. The work of organising the proceedings was entrusted to good hands when it was given to Professor Allen. From the programme which had been prepared, and the enthusiastic reception which had been given to members, he judged that the Second Session of the Congress would prove a thorough success. The motion was carried by acclamation. The President then invited the Hon. Duncan Gillies, Premier of Yictoi-ia, to welcome the visiting members. THE president's INAUGURAL ADDRESS. 9 THE PREMIER'S ADDRESS OF WELCOME. The Premier (Mr. Gillies), who was received with cheers, spoke as follows : — Your Excellency, Mr. President, Ladies and Gentlemen, — I have been requested to offer a cordial and hearty welcome on behalf of the Government of the Colony of Victoria, to those gentlemen who have come from the other colonies and elsewhere, for the purpose of attending this Congress. It must have been to them no small sacrifice to leave their homes, when they were engaged in important work, to attend the conference, but they have the satisfaction of knowing that they will probably be engaged in still more important work. I venture to think that no higher duty could be performed by medical gentlemen, than to attend a Congress where matters of the greatest moment will be discussed. The work of medical men is all important, for what better office can there be than the amelioration of suffering humanity ? I feel quite confident that the labours of this Congress will be commenced in a desire to ascertain the truths of medical science, and to obtain more information than members possibly have at present with reference to the difficult questions that will be brought up for discussion. The labours of the members ought to do good, and I am quite sure that they will. I trust that members generally will be animated by a desire to help forward the greatest mission that any body of men can possibly be engaged in, and that is, the promulgation of sound laws for the protection of health and the removal of disease. THE PRESIDENT'S INAUGURAL ADDRESS. The President (Mr. T. N. FitzGerald) then delivered the following Inaugural Address : — Your Excellency, Members op the Congress, Ladies and Gentlemen, — When last year, at the first Medical Congress ever held in the Australasian Colonies, I was chosen President-elect of the next similar gathering, I was very proud to have obtained such an honour. I received with feelings of ]irofound gratitude the expression of confidence and regard that my fellow-workers, in the noblest of all vocations, were so good as to convey to me. And now as I stand before you, who have come hither from ever}'' part of Australasia to take counsel together on matters of grave import, I feel that I have reached the crowning point of my ambition ; for I need hardly say, that although material success is very ])roperly an object we may all laudably strive to win, if only we strive fairly and honorably, a still higher {)rize is that which is conveyed in the willing trust of a whole brotherhood. I wish, therefore, here to declare how deeply sensible I am of tlie honour of which I was then made the recipient, and how pioud I am to occupy the place that now I 10 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. fill. Let me, however, sincerely assure you, that I feel conscious of considerable diffidence in having so closely to follow the late President, whose eloquent address in Adelaide won from us such enthusiastic and well-merited recognition. And now let me offer you all a cordial welcome to Melbourne, which some of you, I dare say, behold for the first time. Our city has been called " Marvellous Melbourne," and no doubt for some reasons it deserves the title. It is very far from perfect, as we who have lived in it so long very well know. To it, then, such as it is, I bid you welcome! We will endeavour to make your stay in it as agreeable as we can, so that when you leave us, you may carry away hot unpleasant reminiscences of your vi.sit. Gentlemen, before proceeding further, pei'mit me to offer a few words of explanation. You are no doubt aware, before we left Adelaide, it was agreed that the Congress should be convened in 1890, and this resolution would doubtless have been adhered to, had not the political authorities of the day suddenly decided to hold the Centennial Exhibition and invite all nations. When the Commissioners were debating their preliminaries, a [(reposition was started that this would be a very favourable opportunity for holding the next session of the Congi'ess. The suggestion at first encountered serious opposition from many who are generally fore- most in support of any movement that tends to the advance of medicine, and whose ojjinions deserved most attentive consideration. The change contemplated was no doubtanimpoi-tant one, more especially as it involved a direct departure from the resolution tacitly agreed upon in Adelaide; but it was urged that, although a year's time was a very shore interval between the two meetings, and allowed but a brief space to collect fi'esli facts and arrange material, yet the chance Avas too opportune to l)e missed. At another time, the means of travelling from distant parts would not be so easy, and assistance from other sources might not be so readily attainable. Consequently it was determined, oh a full vote of the profession, to alter the Adelaide programme, and to convene our gathering this year. The date being fixed, those who had opposed the alteration the most strongly, veiy generously consented to act with the lai'ger section, so that we have since worked together in pei'fect harmony in making the preliminary arrangements. I am delighted to say that the fear expressed by the opponents to the change, that the time would be too short to collect sufficient material, has not been justified by results, and that we have experienced from all quarters a most gratifying readiness to co-operate with us in making the Congi-ess an unqualiHed success. It has been asked, what are the especial advantages to be looked for from an Australian Medical Congress 1 What practical good is likely THE president's IXAUGURAL ADDRESS. 11 to come from the gathering together of medical men in these southern hands? Are there, it is demanded, any diseases peculiar to Australia, or affections which have not been investigated exhaustively liy the higliest authorities in Europe ? Do the conditions of climate and the social habits of the people modify diseases ? Or do certain affections, which are common to all hititudes, assume here particular characters that difierentiate them from tlie aspect they present under other geographical circumstances 1 AVell, I do not forget that, on the other side of the world, and especially in those large centres of human life where the perils of existence and the factors of disease are so many and so constant, the finest intellects are contimially engaged, investigating in every branch and every branchlet of the com[)ound science of medicine. They have abundant means, elaborate appliances, the fullest opportunity and uninterrupted leisure at their command, to work out the problems "which continually are spread before them. The microscope enables them to make additions every day to the sum of that division of the medical sciences, which half a century ago, or even less, may be said to have had no existence. Histology is thus always revealing to them, and through them to the whole medical world, something new. The chemist in like manner is for ever throwing light upon etiology, pathology, and, especially in its larger significance, therapeutics. There are very many highly accomplished men content in their enthusiasm to spend the spring-time and early summer of their lives in the exhausting work of hospital duty, happy and well enough rewarded in their own esteem, if they but do now and then, amid the thousands of routine cases they have to treat, light upon some new clinical fact, or discover some hitherto un)-ecognised action of a drug. Surely, asks the ])essimist querist, your local medical societies suffice for the re[>ort of unusual cases, and the exhibition of anatomical peculiarities or rare distortions; why then, with puny strength, endeavour to emulate the mighty efforts of the northern hemispheres, having in remembrance that some of their endeavours have not been crowned with perfect success 1 We do not, we cannot hope to bear comparison with the great medical gathei-ings of the congresses or associations in Europe. But with all becoming humility, and with the admission that we cannot hope for some years successfully to rival our l)rethren in the healing ciaft in the old world, I have yet to say that we have here three thousand medical men, educated and trained in the same way, and qualified \\\) to the same limits, as are those at home. We have amongst us representatives of nearly every medical school or college in Europe, who have opportunities of studying and treating disease and of maturing their knowledge, both in private and hospital practice. Then again, as we all well know, in 12 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. many medical and surgical affections, the practice adopted by some of the leading men in the different colonies is decidedly at variance (whether rightly or wrongly) with the views held by home authorities. Surely therefore we are able to add something to the sum of that knowledge which we have as a kind of joint-stock, and to the en- largement of which it should be both our duty and pleasure to contribute. To reply further, it should be remembered that though the habits and conditions under which we live bear a social similitude, yet they are by no means identical with those existing in Europe. In the older civilizations and in America, we see the working population of the cities crowded together in a manner utterly unknown to us. The facts lately published by the Special Sanitary Commissioners of the Lancet, on the sweating system among tailors in Liverpool and Manchester, must be an incomprehensible revelation to the native born of these colonies. In the rural districts of the old country, the labourers are ill and insufficiently fed, ill-clothed, over-worked, and everywhere subjected to the extremes of cold or heat in their seasons. The wealthy, for the most part, especially the females, are fashion worshippers, self- indulgent, and almost entirely unemployed, the more active alone finding vent for their energies in eleemosynary efforts. With us, on the other hand, the cities are wide spread (too much so if anything), each man, even to the poorest, lives in his own house, animal food is plentiful and cheap, the hours of labour are short, and summer and winter are much the same, except that in their seasons occasionally the hot days are hotter, and the cold days are colder. Such weather as is implietl by the terms zero, blizzard, continuous rain, ice-storms, &c., we are unacquainted with, unless through newspaper description. On certain days it is true the heat is apt to be opi)ressive, especially to the inactive, and trying to the aged and sick, yet it can never be said to be unbearable or inimical to life. Then again, the difficulty and often impossibility of ensuring constant domestic service, com])el even the most opulent of this connnunity to do for them- selves what they would be glad to pay others to do for them ; and thus, in the performance of household work, our gentlewomen procure for themselves an amount of bodilv exercise, which, although unsought and sometimes unwelcome, is a distinct benefit to them, and there can be no question that it saves them from many ills to which they would otherwise be subjected. Thus then, in this continent we find men of all classes living under the most favourable circumstances, climate nearly all that can be wished for, healthy inheritance, both mentally and physically, ample space for every one, and well requited industry prevailing everywhere. I THE president's ixaugural addhes.s. 13 Surely witli these ha})!)}' surrouudiugs, which exist, as far as I am aware, to such an extent in no other place, we have a spacious field, es[)ecially our own property, for investigating disease as it occurs uninfluenced by the many causes which excite and maintain it at home. For instance, we have long been taught, rightly or wrongly, that scrofula and tubercle are affected by squalor and dirt ; that phthisis is favoured by close vitiated atmosphere and cold night air. These causes are present but to a slight extent with us, yet occasionally we find scrofulous impregnations excessively virulent; while phthisis is as common with us as it is in England, and decidedly more so than in Canada and Scotland. Again, here in this land, certain acquired constitutional diseases in the tertiary ulcerative forms, such as rupia, are comparatively mild affections, and seldom present that grave character which is such a continual source of anxiety to the European practitioner. As a corollary to the limited intensity of such affections, we would expect to find skin diseases rare and mild in character. Is this the case 1 We are a busy people, yet melancholia is a common form of insanity to be met with in our asylums. Then again, do we enjoy an immunity from the nervous diseases so frequently to be met with in the great manufacturing and mercantile centres of Great Britain 1 And if we do not, what is the explanation 1 It is not difficult to discover, therefore, that the field for observation is here veiy wide, and that in whatever direction of special knowledge we may look, there is an abundance of matter to intei-est and occupy us, without at all travelling over trodden paths, or turning over ground which has yielded up all its nutrient elements to the cultivator. There are a number of similar questions in which our peculiarly happy circumstances will perhaps allow us, by a process of elimination, to throw a light on obscurities, and to regard causes from a point of view from which, without these advantages, they cannot be seen by the profession at home. So too, should we ask ourselves, cannot advantage be taken of our almost unlimited space to bfing under control such distressing social maladies as habitual drunkenness? Then again, is not this the opportunity to come to .some agreement as to where a suitable mountain x'esidence can be found for the delicate and consumptive 1 Whether a better treatment may not be advised in counselling protracted change — summering in New Zealand or Tasmania, wintering in Queensland, and spending the intermediate time in one of the other colonies ? — for we have all climates with us. To arrive at any definite conclusion on these and many other matters, a consensus of opinion is required, and this can only be obtained by such a gathering of the profession as T see before me now. 14 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. If our environments are healthful, and certainly they should Ite so, the young manhood of this country, who, for the past few years only, has become an influence in its Councils, should present a type of the highest class. His birthright, the jjolitical freedom which has been handed down by his fathers ; his inheritance, the home life, the decorum and gravity of a race bred under a cold ungenial sun : untrammelled educational establishments at his very door; no class distinctions to sneer him down, and every opportunity to gratify any inclination either in the playground, the workshop, or study — the Australian native should stand forth as the creature best able on eartli to resist disease, and the mo.st willing to listen to wholesome advice on sanitation. His love of out-door sports, engendered by easy hours of labour and the many open reserves, sa\'es him from the several temptations which surround life at the time of its pubertal development; whilst the constant sunshine, the frequently recurring holidays, and variety of amusements relieve his toil from the chilling monotony that in other countries is the parent of habitual intemperance. Why then, in such an apparent paradise, peopled by those who ought to be Hercules and Apollos, are our death rates so high 1 This is a question thtit doubtless tliis Congress will enquire into, and its deliberations will, I trust, throw some light upon these vexed matters of drainage, ventilation, and the other items that so intimately affect the sweetness and healthfulness of life. I wish,^ however, to draw attention to one or two points which, though perhaps well known to the profession, are not generally recognised by the public at large. In all English-speaking communities, the mortality bills are swelled ])rincipally by three affections — alcoholic intemperance, tubercular deposits, and typhoid fever — scourges in the main j^reventable ; but the remedies for which, either from their expense, or from other causes, we will not boldly and manfully face. Firstly then, with regard to drink. You all know how inimical to treatment its effects are, and how great is the misery it occasions. I have no wish to read you a teetotal lecture ; there is, however, one peculiarity which stands out rather prominently, and which I think should have weight with us all, when, as medical men, we are called upon to prescribe spirits as a drug; and that is the fact that alcohol is much more potent with us than it is at home. If we turn to the statistics that Mr. Hayter annually furnishes to the Government of Victoria, we find that the deaths set down to drink are numerous compared with those of even the most intemperate countries ; and such a calculation would naturally lead to the assumption that we Australians are an extremely drunken peojjle. I do not desire to go out of my way to find excuses for much excess in this particular, nor THE president's inaugural address. 15 would it be proper for me to say that tliere is no di-unkeniiess in Australia, but I assert with the strongest emphasis that habitual drunkenness is an exception with us. Visitors from abroad who have been to any of our great gatherings, at military displays, ar.d racing carnivals, or who have seen the crowded attendances at athletic meetings in any of the colonies, must have noticed the absence of drunkenness and rowdyism. What really is the case is, that alcohol, in whatever form it may be taken, is not suited to the climate or the conditions of the people, so that hei)atic and renal atTections are sooner and more frequently engendered by its use tlian they would be under the same circumstances in a colder country. Looking at the habits of Eui'opean populations, however, I cannot but regard it as a slander upon our manhood, to charge them with systematic drunkenness. A great number of our native-born youths are total abstainers from birth, and, while not forgetting the intemperate opinions sometimes expressed by temperance advocates, I must admit that tem[)erance societies have worked a great deal of useful reform. As a food in the low delirium of fever, and as a means of preventing waste of tissue in erysipelas and kindi'ed diseases, and for the aged, alcohol is doubtless essential and of great service. Yet the death-rate ought, I think, to teach us the necessity of care in the use of intoxicating liquor, and that, as medical men, we should be veiy cautious, far more so than our brethren have need to be in colder climates. What we have to regard is the great probability of its continued and over-modei-ate use being prolonged when the necessity for its employment has ceased, and of its setting up local congestions, which, in time, destroy the functions of the organs they aifect. Of Phthisis and Typhoid Fever, I have already said that the former appears to be nearly as common in Australasian as in English towns; and typhoid, both in urban and rural districts, is nearly of twice as frequftnt occurrence. I think it offers occasion for the gravest consideration to discover how, in a country so richly endowed, and with a climate so genial, we should yet be afflicted to so terrible an extent with two diseases of parasitic origin, both of which, pathologists assure us, are eradicable. It is curious to notice how the etiology of phthisis has varied amongst physicians from time to time. In my early days, it was impressed upon us that consumption chiefly arose from defective ventilation, and the inhalation of irritant [)articles. Then came the catarrhal or pneumonic origins — neglected colds and so forth, and now we find that neither nor all of the.se i-easons will suffice to account for the large bills of mortality from phthisis in tliis land. In my opinion, next to its hereditary incejjtion, the greater part of phthisis will be found to be associated with defective drainage, 16 INTERCOLONIAL MEDICAL CONGRESS OF AUSTUALASIA. and this, I believe, will be proved by bacteriology. I cannot but think, therefore, that it will always be endemic with us until we devise some proper and complete method of carrying ofF our sewage and fluid house refuse. Typhoid fever is with us a true opprohrium medicorum. It is with us, of us, among us, upon us. It is a spectre we apparently cannot exorcise. It is truly " the pestilence that walketh in darkness, and the destruction that wasteth at noonday." It is at once a terror and a reproach. It defies legislation and administration, it laughs at boards of health, and triumphs ruthlessly and always. Are we never to cope with this terrible affection 1 As far as Melbourne is concerned, we hope much from the Commission which is now holding its meetings ; and we trust that whatever scheme is decided upon, it will be adopted without the long delay that generally follows the decisions of such bodies. But in the meantime, the same things go on. Streets are marked out, and houses are built without the semblance of drainage. Then the warm weather comes, and fever stalks each year more greedily and viciously than before. No doubt the section constituted to discuss matters relating to hygiene and public health will indicate what steps modern sanitation should take towards the suppression of this conspicuous evil. The views of medical men and health officers are always valuable when they take some practical form, especially on such a subject as public health. On such matters they alone, from their educational training, are capable of expressing opinions worth listening to. I sincei-ely trust our health boards will derive information from the deliberations of the Section of Hygiene. Gentlemen, all branches of our profession seem steadily to advance. Annually some new surgical measures are contrived, some new drugs are introduced, some disorders discriminated. What future is there for Sanitation 1 Sanitation, unlike other divisions of our art, must go hand in hand with the educational progress and mental improvement of the people. Without the schoolmaster, all efforts we could make must inevitably prove futile. An intelligent conception of its purposes by the authorities, both parliamentary and local, is absolutely necessary. It is here that I hope much may result from such a gathering as this Congress, for in all matters that relate to medical and sanitary require- ments it seems to be nearly an invariable rule for legislative enactments to l)e considerably in arrears. With borough and shire authorities, I believe these bodies do, in the main, the best their lights permit them, ))Ut the insanitary conditions of their respective localities are attributable I conceive to either a want of information, or a reluctance to exercise their powers. Ijccause diphtheria happens to be absent for a time from their district, they fail to see danger in a cesspit, or the necessity of THE pjjksidhnt'.s inau(;ukal audhkss. 17 milk inspection, and so fortli. Doubtless the advanced education the young are receiving, in at least the better class of schools, the instruction in the elements of physiology and the general principles of hygiene, will in time have its etiect on our future statesmen and councillors. And in this direction I think much benefit might accrue from the ajjpointment of a few thoroughly trained and carefully chosen sanitary instructors, whose duty it should be to travel from town to town, and even from house to house, with the object of teaching the principles and the ad vantages of Health Laws, and the consequences of a disregard of them. For it is certain that the value of cleanliness cannot be properly iinder- .stood until the dangers of filth are comprehended. I should like while on this subject to say something in strong praise of the hygienic an^angements that have been carried out in Adelaide. The method of diainage apjiears to be as nearly perfect as it can well be, and as there is a large model of the system in the South Australian Court of the Exhibition, it would be well that every one interested in this subject should see it. If it be i)0ssible to adopt in this much larger city the same system, 1 am jirepared to say that the death rate would be lowered to an extent now hardly dreamed of. Nor is the incidental advantage in connection with this system of the disposal of the sewage to be lost sight of. The Adelaide sewage farm is a very joy of scientific agriculture. In Sydney they ,ai'e commencing Avith earnestness to drain their busy city ; and although the undergi'ound drainage of Melbourne is at present little more than rudimentary, we have at least made a beginning. But what is more encouraging, and prognosticates well for the generation that is to follow us, is the lusty out-door life, and the sturdy games the Australian so dearly loves. Amongst those who ever have seriously revolved the subject in their minds, some doubt must have arisen whether the youth of these great colonies would walk in the stej)s of their parents, or, influenced by a hotter sun, follow in the wake of their American kinsmen, and forsake the green sward for light amusements, ease, and luxury. I rejoice to say that this question is entirely set at rest, the Australian's prowess on the river and the cricket field has settled that matter, and he promises, as far as physical development goes, to even surpass his fathers. It is rather extra- ordinary that the out-door life and national games of the mother country should have taken such a hold on the young folk of Australasia, for I believe in no other ]iart of the world have the sons of the Anglo-Saxon or Celtic emigrants done the same. Certainly, in America or South Africa, neither cricket or football is generally played. Now the love of these manly games must ]m\e an influence for good on the manhood of this countr}-. Personally, I have no c 18 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. sympathy with those who would decry these athletic exercises, either because at tiuies they may be carried out too roughly, or sometimes are accompanied by some degree of danger. The very roughness of football is an element of good. It developes courage and good temper; one hears too much now-a-days about gentleness and the velvet hand. We require a little fibre which these games tend to impart. When I look at the footballer ready for action, I cannot help admiring his muscular frame, and sympathising with him in the pride he takes in his sturdy limbs, his form and activity. Contrast him with the boy one meets with on the Continent, ))arading through the streets, W^hich is the more likely to grow up a self-reliant, useful citizen, the footballer or the young gentleman who spins his tops and bowls his hoops in gravelled enclosures 1 Depend upon it, these games are important factors in the formation of the moral tone of this country. We should encourage them to the best of our powers, and endeavour to allay the fears of timid over-anxious parents. If a few limbs are broken annually, and even now and then unfortunately a death occurs, it would be better that four times the number of casualties should be told, than that our boys should grow up hypochondriacal and dyspeptic. Looking round this assemblage of representatives of the great Guild of Medicine, drawn here from every province of Australasia, I cannot deny myself the pleasure of thinking that we are all students, still engaged in the work upon which we entered, some of us, many years ago. We have had our ambitions, our difficulties, our trials, our disappointments, and now and then our successes. We have been ensased in the hard business of living ; we have had to contend with opposition on many occasions, and sometimes we have had good reason to believe we were not too fairly dealt with. However, I am sure it has been the consolation of all of us to feel, that in the acquirement of the knowledge necessary for the exercise of our craft, wc commanded a source of enjoyment tliat nothing in the way of fret or ill or mere professional failure could take from us. We have thus all added something to the common store of medical knowledge. We have in this way experienced a delight compared with wliich the greatest material success holds only subordinate place. Like another God-like attribute, the ars medendi " blesseth him that gives and him that takes." It is a deliglit to make discovery in our science ; but I am sure it is a delight still greater to know that the discovery may be of service to our professional brethren in relieving suffering humanitj'. It is thus a privilege to thank God for, that our domain of discovery can never be exhausted, and that no matter how great may be the researches of others, there is still left room for us to go on exploring. It is the very glory of medicine that it is not finite. It has been brought THE puesidext's inaugural adduess. 19 against it as a reproach, that both its principles and its practice are always undergoing changes. I reply, with a feeling of triumph, that these changes are the very evidence of our progress. If we have a motto at all, it is " Onward." It is not our despair but our boast, that medicine is not an exact science. We are not content with what we have done, but we look forward to the greater, the better, and the higher doing. *' Still achieving, still pursuing " we " learn to labour," and if we " wait " at all, it is not in the dull apathy of contentment at what has been done, but in the belief that " the Greatest is behind." It is with this feeling, this liope, this ever constant and unswerving faith, that I regard the coming together of my brethren on this the opening day of the Second Session of the Medical Congress of Australasia. The Hon. Mr. Creed (Sydney) moved a vote of thanks to the President for his learned and useful address. Mr. FitzGerald, as the head of his profession in Victoria, was fitly appointed President of the Second Session of the Intercolonial Medical Congress of Australasia, and his medical brethren were proud to elect to that high and honour- able position a gentleman who was not only the most illustrious sursreon in Australia, but who had also a world-wide fame. No two more worthy representatives of the profession could be found than the Presidents of the First and Second Sessions of the Congress. At the close of the Session held in Adelaide, it was suggested that three years should elapse before the next meeting, but no definite decision was made on this point, the question being remitted to the medical societies of Victoria. The practitioners throughout all the colonies rejoiced that the interval had been reduced to eighteen months, for the jDrogramme of work now submitted showed such a mass of interesting matter to be dealt with by learned and distinguished men, that the assembling of tlie Second Session at this early date must be a gain to society and to the profession. Members were indebted to the President for many useful and practical suggestions, wliich must lead to earnest thought on tlie part of his hearers, and thus sooner or later bring benefit to the public. Even to the latest years of tlieir pro- fessional lives they were still students, ready to learn from anyone wlio could help them to higher knowledge of their science. This was an age of federation, and to the medical profession of Australia belonged the credit of making the first practical suggestion of a federal character, viz., the establishment of a federal quarantine .station, the absence of which was dangerous to the health, commerce, and prosperity of the colonies. Dr. E. C. Stirling (Adelaide) had very great pleasure in seconding the vote of thanks to the President. No one was better qualified tlian C 2 20 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Mr. FitzGerald to speak with authority to tlie Intercolonial Medical Congress, and his address was marked by that thoughtful suggestiveness which characterised all his work. The President had also shown to the public that a medical address need not be dry and uninteresting. Mr. FitzGerald's name was a household word, not only in Victoria, but throughout tlie Australian Colonies, and it was, therefore, unnecessaiy for him to say one word to induce the Congress to carry the vote of thanks by acclamation. The Congress rose en masse, and cheered long and lustily. The President said: — Your Excellency, Ladies and Gentlemen, ■ — T really feel too overwhelmed to say anything in acknowledgment of your most hearty vote of thanks. I can only thank you, and I do thank you very sincerely. Dr. Manning (Sydney) proposed a vote of thanks to His Excellency the Governor, for the kind and gracious manner in which lie had opened the Congress, and also for his address. His Excellency had shown such a warm feeling for the profession, such a sympathy for its woi'k, and such a general appreciation of its liigher aims and objects as must have gone straiglit to the heart of every member of the Congress. Dr. J. Davies Thomas (Adelaide) seconded the motion with great cordiality. His Excellency liad honoured tlie medical profession by his pi'esence at the Congress, and its members had also to thank him for the generous and liospitable welcome he had gi\en them. The motion was carried Ijy acclamation. His Excellency the Governor, in acknowledging the compliment, said : — Dr. Manning, Dr. Thomas, Mr. President, Members op the Congress, and Ladies and Gentlemen, — I thank you very sincerely for the kind reception whicli you have given to the vote of thanks which has just been accorded to me. I can assure you it has given me very great pleasure to come here to-day to declare this important Congress open, and I only wish I may be permitted to be present on some of the occasions when the valuable papers, of which I have seen a list, will be read before the Congress. Dr. Manning referred to the fact that Mr. FitzGerald's address was so interesting that it could be appreciated by laymen as well as by medical gentlemen. I can assure you that many of the papers which will be re;ul at the Congress, can and will be appreciated by laymen just as much as by gentlemen of the medical profession. Altliough they may not lie so well understood by laymen as by medical gentlemen, they will lie equally interesting to laymen, and as higlily appreciated by them. Mr. FitzGerald, in his address, has referred to many matters of very great importance — of importance not only to the medical profession and the world at large. RECEPTION HY THE MAYOR OF MELBOURNE. 21 but of special iniportaucc as art'ecting this colony, and this great city of Melbourne in particular. He has referred to those questions and sanitary considerations which are now occupying the attention of the (rovernnient and of the public very deeply, and I trust that the deliberations of the Congress on the important questions that may arise, will lead to wise aTid sound conclusions. I thank you xevy sincerely for the cordial reception you have given me, and I can only say on my own Ijehalf, and on liehalf of Lady Loch, that we are looking forward with very great pleasure to receive you on Wednesday night. The General Secretary announced the succeeding business of the Congress. The President then declared the Congress adjourned until 8 p.m., at the Freemasons' Hall. RECEPTION BY THE MAYOR OF MELBOURNE. At half-past 1 o'clock the members of the Congress, with other guests, were received by the Mayor of Melboui-ne (Alderman B. Benjamin) at the Town Hall. The reception took place in the Council Chamber, and at 2 o'clock the guests were invited to partake of luncheon in the main hall. The Mavor occupied the chair, having on his right the President of the Congress (Mr. T. N. FitzCerald), the Minister of Public Instruction (Mr. Pearson), the Speaker of the Legislative Assembly (Mr. M. H. Davies), the Government Statist (Mr. H. H. Hayter, C.M.G.), and the Chairman of the Board of Railway Commissioners (Mr. R. Speight). On the left of the Chairman were Sir Henry Parkes (Premier of New South "Wales), the President of the Legislative Council (Sir James MacBain), the Minister of Education of South Australia (jNIr. J. C. F. Johnson), the Chancellor of the University of Melbourne (Dr. A. C. Brownless), the General Secretary of the Congress (Professor Allen), iuid the Government Botanist (Baron F. von Mueller, K.C.M.G.) After the customary loyal toasts had been honoured, the Mayor proposed " The Governments of the Sister Colonies." Sir Henry Parkes, on rising to respond, was received with loud applause. In the course of an eloquent speech, he said : — I have no doubt that this great assemblage of learned doctors will result in great good to the cause of science, and if so, as a consequence, great good to our common humanity. I happen to be one of those who have learned as one of the sums of my experience, that several of the greatest men in all acts of practical benevolence, and in all acts that tend to ])romote the progress of the world, are enlightened jihysiciaiis. Certainly, there is no sphere of human action which opens grander avenues of usefulness than that of the physician, and to the honour of the profession there have been no greater men — no more bene^•olent benefactors — than many men who have honoured that most honourable profession. Mr. Pearson, in responding to the toast of "Her Majesty's Ministers in Victoria," said that a few yeai's hence, when it fell to the lot of the 22 INTERCOLONIAL MEDICAL CONGRESS OF AUST8ALASIA. Mayor of Melbouine at that time to ]jropose the healtli of Her Majesty's Ministers in and for Victoria, the toast might be replied to by a Minister of Public Health. He had carefully said that such an e\ent might come about some few years hence, not because he had the slightest doubt that such an office was terribly necessary at the present time, but because he was convinced that public opinion was not ripe for it. To create a })ortfolio, and to entrust it to the charge of a gentleman who had not the power to carry out what he knew to be needful, would be the most tremendous of raockei'ies, and at the present time people valued certain constitutional rights too highly to admit of that desirable change — the right of a man to pollute running water, the right of a man to spread contagious disease descending even to the third generation, the right of a man in every possible way to poison the life springs of the comniiuuty — and many men would oppose to the death any interference with the piivileges he had named. The corporation of Melbourne had honourably endeavoured to do its best to promote the health of the community, but he could not say the same of some of the boards of health in the metropolitan suburbs. He looked forward with dread to the time, which was certainly approaching, when the diseases which had been deliberately created, and against the fostering of which medical men and scientists had raised their voices for years })ast, would visit almost every household like the angel of death, and take away their spoil. A Minister of Health wonld be appointed when the community deu>anded a reform in regard to matters affecting the [lublic health, and told the Government of the day to arm the Minister of Health with all powers necessary to sweej) away all the evil products of the vested rights to which he had referred. But he felt that he was wandering from actual life into Utopia. We were living in the nineteenth century, and if such a reform were proposed, it would be denounced by the press as grandmotherly legislation, because it would be an inter- ference with the vested right of ever}' Englishman to carry death into his neighbour's household, and the Government that took the step would be swept out of power. The Mayor, in ])ropo8ing " The Intercolonial Medical Congress," expressed the pleasure which it had given him to be present at the inaugural ceremony. The Congress had assembled for the i)uri)ose of discussing matters of the gravest importance to the whole of Australasia, and he had no doubt that the result of the deliberations would be highly satisfactory. The President of the Congress, in proposing *' The Health of the Mayor," retui-ned thanks to him on behalf of the Membeis of Congress, for the ma'niiticent manner in which he had entertained them. EVENING SITTING. The Congress re-assembled at 8 p.m , in the Freemasons' Hall. His Excellency the Governor was present. Mr. T. N. FitzGerald, President of the Congress, occupied the chair. The Address in Medicine was delivered by the Honorable W, F. Taylor, M.D., M.P. (Brisbane), President of the Section of Medicine. THE phksident's dinner. 23 The Address in Anatomy and Physioiogy was delivered by Professor T. V. Anderson Stuart (Sydney), President of that Section. On the motion of the President of the Congress, hearty votes of thanks were accorded to Dr. Taylor and Professor Stuart. The Congi'ess then adjourned till the following day. SECOND DAY. TUESDAY, JANUARY 8, 1889. At 10 a.m., in the Pathological Museum at the Medical School, Dr. Maudsley demonstrated a collection of gynaecological si)ecimens. At 11.30 a.m. the Congress re-assembled in the Wilson Hall, the President, Mr. T. N. FitzGerald, occupying the chair. The Address in Surgery was delivered by Dr. E. C. Stirling (Adelaide), President of the Section of Surgery, and the Address in Obstetrics and Gvmecology by Dr. Batchelor (Dunedin), President of that Section. Cordial votes of thanks were passed to Dr. Stirling and Dr. Batchelor, on the motion of the President of the Congress. The Congress then adjourned for luncheon, which was prepared in one of the large rooms of the ^Medical School. In the afternoon, the Congress was divided into its Sections, which met in the various lecture theatres of the University. THE PRESIDENT'S DINNEPt. In the evening, the President of the Congress, Mr. T. N. FitzGerald, entertained the fliembers and other gue.sts at dinner in the Town Hall. His Excellency the Governor was on the President's right, and the Premier of Victoria (Mr. Gillies) on his left. Among those present were the President of the Legislative Council (Sir James MacBain), the Speaker of the Legislative Assen)bly (Mr. M. H. Davies), the flavor of Melbourne (Alderman B. Benjamin), the Minister of Public Instruction (Mr. Pearson), the Commissioner of Public Works (Mr. Nimmo), the Chancellor of the University (Dr. Brownless), Mr. Justice Wrenfordsley, and the Executive Vice-President of the Centennial International Exhibition (Colonel Sargood). The toast of "Her Majesty the Queen" having been honoured, Thk President proposed "His Excellency the Governor." He remarked that His Excellency was always associated with everything good and charitable, and was ever ready to lend his support to any public movement of a pi-ofessional or scientific character. The success wliich had attended the opening of the Congress, was in no small measure due to His Excellency's influence and to the gi'eat interest he had taken in the Congress. His Excellkncy thf: Govehnou, in responding to the toast, said he took a great interest in the Congress, as he was of opinion that it would ])rove of immense benefit to the Colony of Victoria and to Australasia. He trusted that the visiting members would thoroughly enjoy liiemselves M'hile peiforining the important duties which had brought them together. Amongst the various {lapers that would be read at the 24 IXTERCOLOyiAL MEDICAL COXHRESS OT AUSTRALASIA. Congress, anrl the discussions which would take place, there were none which would interest the people of this Colony more than those on the subject of sanitation. In the ])apers which he had heard read the previous evening, reference was made to the death-rate in England and the death-rate in these Colonies. There must be some cause for the death-rate amongst children in the Australian colonies being so much in excess of that at home, and it behoved the medical gentlemen who were now assembled in Congress to inquire into the nature of these causes. We were vei-y apt in Australia to l>e seized with alarm at the bare pi'ospect of cholera being imported here, and yet we were most neglectful in providing against typhoid fevei'— a disease which was carrying oft" thousands of the population. The Minister of Public Instruction had, at the jNIayor's luncheon, referred to the a])athy of the public with regard to the steps which it was requisite should be taken to guard against typhoid fever. He cordially agreed with the expression of opinion that Ixad fallen from the Minister on that occasion. It was wonderful that there should be such an apathetic state of feeling amongst the peo))le of this country on the subject of health. It was that apathy which ]irevented the necessary steps being taken to guard against the fell disease which was decimating the population. He earnestly trusted that the result of the conference would be to awaken public opinion upon this important matter, and that something definite would be done towanls imjtroving the sanitary condition of the Colony, and of Melbourne especially. The subject he had touched upon was not a political one, and therefoi'e he had felt himself justitied in referring to it. The Premier (]\Ir. Gillies) proposed "The Intercolonial Medical Congress of Australasia." The toast was not merely a personal one, as it involved the success of the mission of the members. Tiiat mission Avas a noble one, as it aimed at relieving human suffering. The medical profession was one of the grandest under heaven, for it had probably done more good for humanity than any other. The study necessary to make men acquainted with all the known facts of medical science was a lifelong one, and members of the profession had often to undergo hard.ship in order to alleviate the sufferings of [tatients. The President, in responding, said that there were over 550 mem- bers in the Congress, and the success of the gathering was already assured. The members were deeply indebted to the Government — and to Mr. Cillies personally — for the assistance and encouragement they had received from the State. The Chancellor op the University of Melbourne (Dr. Broavnless) in i)roposing ''Visiting Members of the Congress," referred to the progress which had been made by the medical profession in the colonies. THIRD DAY. WEDNESDAY, JANUARY 9, 1880. At 10 a.m., in the Pathological Museum at the Medical School, Professor Allen demonstrated a large collection of hydatid cysts in various organs. Sjtecial deiuonsrratioiis and operations were conducted in the various Hospitals. RECKPTIOX AT GOVKHN'MKNT rrOUSK. 20 At II a.m., a General ftfeeting of tlie Congress was held in the Wilson Hall, when papers were read and discussed concerning the geographical distribution, jiathology and treatment of Hydatid Disease. The Chair was occujned by Dr. E. C. Stii'ling, President of the Section of Surgery. i\rend)ers were in\ited by the Connnittee of the Hospital for Sick Children, to visit that Institution at any time. At the close of the meeting the Congress adjouined for lunch, which was ])rovided in the Medical School. The afternoon was devoted to Sectional INIeetings. His Excellency the Governor visited the Congress during the afternoon, and was present at the Physiological Demonstrations conducted by Professor Anderson Stuart. PvECEPTION AT GOVERNMENT HOUSE. In the evening. His Excellency the Governor and Lady Loch entertained the Members of Congress at Government House. The company numbered upwards of a thousand ladies and gentlemen. All the state rooms were thrown open for the use of guests, who were welcomed by His Excellency and Lady Loch. FOURTH DAY. THURSDAY, JANUARY lU, L^S9. In the forenoon, a large number of Members visited the AVomen's Hospital, and were received liy the Ladies' Committee and the Honorary Medical Stafl'. At various other hos[)itals operations were conducted, and cases were exhibited in the wards. At 10 a.m. in the Pathological Museum at the Medical School, Dr. INfaudsley demonstrated a laige collection of medical specimens. At 11.30 a.m. a General ^Meeting of Congress was held in the Wilson Hall, the President, Mr. T. N. FitzGeiald, occupying the chair. The Address in Hygiene, Forensic and State Medicine was delivered by Dr. H. N. MacLaurin (Sydney), President of that Section, and the Address in Pathology by Di-. W. Caniac Wilkinson (Sydney), President of the Section of Pathology. Hearty votes of thanks were tendered to Dr. ^lacLaurin and Dr. Wilkinson. The Congress then adjourned for lunch, which was again served in the luncheon I'oom at the Medical School. The afternoon was devoted to Sectional Meetings. THE SPEAKER'S DINNER. In the evening, the Speaker of the Legislative Asseud>ly (Mr. M. H. Davies) entertained the MemVters of Congress and other guests at dinner in the Town Hall. About five hundred gentlemen were pre.sent. The Speaker occupied the chair, and had on h's right the President of the Congress (Mr, T. N. FitzGerald), the Minister of Public Instruction (Mr. Pearson), Dr. Kirtikar (India), the Commissioner of Pul)lic Works (Mr. Nimmo), and Judge Molesworth. On his left were Dr. J. C, 26 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Verco (Adelaide), President of the First Session of the Congress, the Minister of Justice (Mr. Cuthbert), the Mayor of Melbourne CAldernian Benjamin), Professor Anderson Stuart (Sydney), the General Secretary of the Congress (Professor Allen), and Colonel Sargood, M.L.C. The loyal toasts having been duly honoured. The Speaker j^roposed " Success to the Intercolonial Medical Congress." It was a good thing for any profession to have such meetings from time to time, so as to interchange views and cultivate friendly relations. The legal profession would reap great advantage.s if, at stated intervals, its members came together to carefully consider questions of general interest, and advise the public concerning necessaxy legislation. The medical fraternity occupied so important a position in relation to public health, that it could command tlie hearty sympathy of the community whenever it assembled in such Congresses as this. It must be acknowledged that whatever tended to advance medical know- ledge, tended also to the saving of life and to the amelioration of ])ain. Everyone should therefore be willing to give a very earnest welcome to those gentlemen, who had at great sacrifice to themselves come to Melbourne, to assist their brethren resident here, in arriving at con- clusions which would be beneficial to the profession generally. He had been asked — "Is it not time that a Minister of Public Health should be one of the leading members of any Ministry ? " The question had been introduced at the Congress, and it had gone forth to the people of the Colony, and possibly it would be asked by electors at the approaching election. It was satisfactory to find that the Congress was likely to be more beneficial than the most sanguine had anticijiated. The President of the Congress (Mr. T. N. FitzGerald), in responding, said that the session of the Congress had not alone served to benefit members individually, but it had done more to federate the j^rofession in Australasia than anything that had occurred in the past. The General Secretary of the Congress (Professor Allen) also responded. He expressed his belief that a time of great change was coming in medical and sanitary matters. He could not agree that a Minister of Public Health was exactly what was needed. A permanent Commissionei- of Health was required. A man was wanted who would be trained steadily year by year in the duties of his position, and who Avould come forward and be the leader of medical and sanitary work in the colony. Such a man was wanted, and not a Minister of Health, who must come and go with each Administration. To keep the Congress supi)lied with original material, .schools of research were needed in every colonial University ; and in Sydney, Mr. Macleay, M.L.C, had bequeathed to the University the noble gift of £40,000 to endow research scholarships. These scholarships were to be open to everyone who had the degree of Bachelor of Science, and, owing largely to the influence of Professor Anderson Stuart, that degree was open on com- paratively easy terms to every graduate in medicine. Who was the man who would make some like provision in Victoria 1 Without it great success could not be achieved. We must have research, and an endow- ment must be secured. He returned his hearty thanks to the local and sectional Secretaries for the valuable assistance they had given him in connection with the Congress. THE speaker's dinner. 27 Mr. Pe.arsox (Minister of Education), in })roposin<:; " Our visitors," and welcoming guests from other colonies, said : — The public which looks only superficially on what is being done — which sees the reports of essays in which the learning is almost overpowered by the eloquence, followed by pleasant and animated discussions, combined with such social gatherings as this — may be apt to think that the ])ursait of science is an extremely light and even fascinating matter. But I need not say to members of the medical profession, that the duties of your lives are of a very different kind. I do not propose to fall back upon the commonplaces of medical history, on the fact that day by day the commonest country doctor, or even town doctor for that matter, is called upon to expose himself to the rigor of the elements, to face infectious disease, and to endure any amount of fatigue. I don't wish to recall here such facts as that of the noble English surgeon, who, when a ship had hoisted the yellow flag, and was without a medical man, went there to die among the patients who were suff"ering from yellow fever. Nor do I intend to speak about such topics as the cholera at Naples, when medical men flocked thither from every part of Europe, to take up the posts left vacant by the medical men who had succumbed to the disease. These doings, gentlemen; you all know, are part of your everyday duties, and yoix accept them in that way ; but it is a different matter when we come into the boundless domain of science. There are those who undoubtedly think that the life of a scientific man is utterly divested of these heroic incidents. I speak from most imperfect knowledge, but even I know that not a single great discovery in the treatment of disease has been made except at the cost of more or less lives, and to the ruin of a certain number of constitutions. For men have died of ])oisoned blood in experimenting with poisons and gases, and in making researches in deadly disease, which they have followed up with as sublime a devotion to science, as ever a mis.sionary felt in the cause of religion. The faith which inspires that devotion, and which animates those sacrifices, is a faith which makes men heroic, and lifts their profession far above that which common men can aspire to. And it is not only in this splendid desire to penetrate into the secret of God's lav that the medical profession has distinguished itself. There is another side to the matter. Every scientific man who has studied disease, as you gentlemen have, goes about the world armed with a mysterious knowledge. Not only is he entrusted with the secrets of families which he never divulge.s, but he is the father confe.ssor to hundreds of men whom it may be he onh' 2)asses by in the streets, but whose histories he reads in their faces or in their gait. In this poor tattling, scandal-mongering world, the fact that you get a regiment of men, recruited indiscriminately from every class, armed with this tremendous knowledge of the secrets of humanity, and keeping it as secretly as the Catholic |)riest keeps the seal of confession, is a fact which in itself marks the profession as no common one. I am called upon to propose the toast of the visitors to the Congress, who have shown that zeal to decipher the secrets of science which I have mentioned as one of the grand attributes of the profession, and who share with others that splendid reserve by which the pi'ofession at large is guarded. To be able to devote lives to the study of divine law, to> be able to draw the veil impenetrably over personal secrets, are, it 28 INTEKCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. strikes me, qualities of tlie veiy liighest kind. I propose the health of our visitors. Professor Anderson Stuart (Sydney), in acknowledsfing' the toast, said that the visitors from the other colonies came to Melbourne filled with the most agreeable anticipations, which had been almndantly realised. Their sojourn had been made both pleasurable and profitable, and they would regret to leave Victoria when the time of their depar- ture arrived. This was a wonderful colony, and Melboui-ne was indeed a marvellous city. I£e never saw the metropolis of Victoria without feelings of admiration for the energy and enterprise of its citizens, and he never left Melbourne without feeling that he had been intellectually stimulated by contact with its leading citizens. For its age the colony had attained to a wondei'ful degree of progress. He hoped the Inter- colonial Medical Congress would one day visit old Sydney, and he could ensure them a hearty welcome to the metropolitan city of Australia. Dr. J. C. Verco (Adelaide), President of the First Session of the Congress, likewise acknowledged the toast. When the First Congress was held in Adelaide eighteen months ago, they exchanged congratula- tions on the fact that there were 150 members, whilst now there were 5.50 members. The ])apers had been of a higher ordei', and the discussions had l)een more complete. FIFTH DAY. FRIDAY, JANUARY 11, 1880. In the morning, operations were performed and demonstrations con- ducted at the various hospitals. At 10 a.m., in the Pathological Museum at the Medical School, Dr. Maudsley exhibited a large collection of surgical specimens. At the invitation of the Committee of Management, a large number of members inspected the Melbourne Hospital. At 11.30 a.m., a General Meeting of the Congress was held in the Wilson Hall, tlie President (Mr. T. N. FitzC-erald), occupying the Chair. Dr. F. Norton Manning (Sydney), President of the Section of P.sycho- logical Medicine, delivered an Address on " Lunacy in Australia." Dr. M. J. Symons (Adelaide), President of the Section for Di.seases of the Eye, Ear and Throat, delivered an Address on " Specialism." Votes of thanks to Dr. Manning and Dr. Symons were carried by acclamation. The Congress then adjourned for luncheon, which was served in the Medical School. At 2 p.m., a General Meeting of the Congress was held in the Wilson Hall, when pai)ers were read and discussion instituted concerning the l)revalence, etiology, jtathology and treatment of Typhoid Fever. The Hon. Di'. Tayhor, President of the Section of INIedicine, occupied the ('hair. CONCEKT AT TJIK ICXIUHITIOX. 29 At the close of the discussion it was unanirnonsly resolved, on the motion of Dr. Verco (Adelaide), seconded by ])\: D. Colquhouu (Dunedin) : — " That the members of the Intercolonial Medical Congress regard it as proved that Typhoid Fever is a preventable disease, which owes its prevalence mainly to insanitary conditions, and above all to contaminated water supply, defective drain- age, and improper disposal of night-soil." The following motion was also carried, on the ])ropo.sition of Dr. Turner (Melbourne'), seconded by Dr. J. Davies Thomas (Adelaide) : — " That while there is reason to believe that the source of water supply of Melbourne is carefully guarded, it is certain that as regards drainage and night-soil disposal the arrangements are very unsatisfactory, and to these defects must be ascribed in a great measure the excessive prevalence of Typhoid Fever year after year. " On the motion of Mi". E. M. James (Melbourne), seconded by Dr. Bright (Hobart), the Congress unanimously agreed : — " Tliat in the opinion of the Congress it is the imperative duty of the Govern- ment to take immediate steps for bringing about an improvement of the sanitary condition of Melbourne, and specifically for the construction of a proper system of underground drainage, which shall include the removal of night-soil by water- carriage." The Congress then adjourned. CONCERT AT THE EXHIBITION. In the evening, at the invitation of the President (Sir James MacBain) and the Conunissioners of the Centennial International Exhibition, the members of the Congress were entertained at a Special Concert at the Exhibition Building. The magnificent Orchestra, under the baton of Mr. Cowen, performed a splendid selection of music. SIXTH DAY. SATURDAY, JANUARY 12, 1889. At 10 a.m., a General ^Meeting of the Congress was held in the Wilson Hall, the President (Mr. T. N. FitzGerald), occupying the Chair. The Address in Pharmacology was delivered by Baron Ferdinand von Mueller, K.C.M.G., President of the Section of Pharmacology. Dr. Neild proposed that a vote of thanks to the ilhustrious savant who had just addressed the meeting, and expressed the hope that the learned i)aper thus submitted would give an impetus to the study of Pharmacology in Australasia. The unceasing devotion of Baron von Mueller to his scientific studies was known everywhere, and his name was held in high honour. The Congress would have been incomplete Lad he been absent from it. Dr. Thomas Dixsox (Sydney) .seconded the motion. Coming from a neighbouring colony, he had been somewhat surprised and much delighted that the Section of Pharmacology had fully justified its existence. The motion was carried bv acclamation. 30 INTEHCOLONIAL MEDICAL COXGRESS OF AUSTRALASIA. SPECIAL MEETING. A special meeting was then lield to determine the place and time, and to elect the President of the next Session. The President (Mr. T. N. FitzGerald) occupied the chair. Dr. Philip Sydney Jones (Sydney) said he had the honour to submit, for the consideration of the Congress, a motion which he felt contident would receive the most hearty support, and an invitation which he lioped would be accepted with the same cordiality with which it was given. The motion was as follows : — " That the Third Session of the Intercolonial Medical Congress be held in Sydney in the year 1892, or at such earlier period as the Medical Societies of New South Wales may determine." It was not the desire of the Sydney representatives present, to bring about the holding of the next Session of Congress in twelve months from the present time, but it might possibly be found more convenient to meet at the end of the year 1891, or to hold the Congress at a pleasanter season of the year, as the summer heat in Sydney was very tiying. For these reasons it was desirable to leave the matter in the hands of the medical profession of New Soutli Wales, who were anxious that the Sydney meeting of the Congress should conduce not only to the editication of the minds of the visiting members of the ])rofession, but also to the invigoration of their bodies. The medical men of New South Wales could not hope to surpass their friends in South Australia or Victoria, either in the perfection of the arrangements for the Congress, or in the sumptuousness of their hospitality, but they certainly tendered to the Congress a most cordial invitation, and would do their best to make the Sydney meeting a thorough success. Dr. Knaggs (Sydney) seconded the motion. The General Secretary (Professor Allen) said he had received from Dr. Dawson, who represented the Medical Association of New Zealand, an invitation for the Congress to meet in that colony as soon as possible; but the New Zealand representatives did not desire that their invitation should interfere with the invitation which had been so graciously given by the representatives of New South Wales. The motion was then put to the meeting, and carried by acclamation. Mr. E. M. James (Melbourne) said it was with great pleasure and confidence that he submitted the following motion : — " That Dr. MacLaurin, the Medical Adviser of the Government of New South Wales and President of the Board of Health, "ue elected President of the Third Session of tlie Intercolonial Medical Congress of Australasia." The Hon. Dr. Creed (Sydney) seconded the motion, remarking that 110 better choice could be made. Dr. MacLaurin not only held first phice in the profession in New South Whales, but also first place in the alfections of his medical brethren, who would feel that the interests of tlie colony would be thoroughly conserved by that gentleman during his tenure of office. The motion was carried unanimously amid loud cheering. The President. — It is extremely gratifying to myself to know that you have selected such an able member of the profession as Dr. MacLaurin, and I am sure you could not possibly have chosen a better President. HEALTH LEGISLATIOX AM) UXQUALIFIKD PUACTITIOXEUS. 31 PRESENTATION TO DR. POULTON. Dr. M. J. Symons (Adelaide) then ro.se, on behalf of the South Austra- lian members, to present to Dr. Poulton a token of ai)iireciation of his services during the First Session of Congress. All members were greatly indebted to him for the enormous work which he did as Secretary to that Congres.s, and iii addition, they remembered that Dr. Poulton was the first to suggest that an Intercolonial Medical Congress of Australasia should be held. A meeting was accordingly heM in Adelaide, and a circular was addressed to the South Australian Members by a Committee consisting of Drs. Gardner, Stirling, Stewart, Thomas, Verco, and Way, with i)i-. Symoiis as Treasurer. In con- sequence, the Committee was enabled to present Dr. Poulton with a silver inkstand, appropriately inscribed, in place of the one which he had worn out in their service, and to add to it a purse of sovereigns, which he now requested the President to pre.sent to Dv. Poulton. The President said it was his most pleasing duty to hand the souvenir to Dr. Poulton, to whose great ability, care, judgment and discretion as General Secretary, the success of the First Session of the Congress was, in a large measure, unquestionably due. He (the President) attended the Congress, and had found Dr. Poulton ready to give information on all needful points, and he only regretted that he had beenexcluded asa Victorian memberfi'om joining in this presentation. Dr. Poulton said: — Mr. President, Dr. Symons and Gentlemen, — I cannot describe the peculiar satisfaction and pleasure with which I receive from my brethren of South Australia this handsome and alto- gether unnecessary memento of a time which I shall never forget. It did fall to my lot as a member of the Council of the local Branch of the British Medical Association to make the first suggestion, so far as I am aware, with regard to holding Medical Congresses in Australasia. Dr. Symons has said that the Congiess is indebted to me ; but I feel myself much indebted to the Congress. I shall always remember the kindness of my Committee, the unfailing energy of its members, and the general cordiality and good feeling which prevailed. I feel deeply the very great kindness which, actuates my friends in giving me this beautiful present. I thank you, Mr. President, for your kind words, and my friend Dr. Symons and my colleagues in South Australia for this expression of their goodwill. Dr. KiKTiKAR (Bombay) said he had the pleasure to offer for the acceptance of the President (Mr. T. N. FitzGerald) and the General Secretary (Professor Allen), co[)ies of one of the oldest native Indian medical works in Sanscrit. He then read a sonnet addressed to the Congress. The President and General Secretary accepted the souvenirs with thanks. HEALTH LEGISLATION AND UNQUALIFIED PRACTITIONERS. Dr. Springthorpe said that, by the instructions of the Section of State ^ledicine, he had to submit the following resolution, which had been drafted by Dr. iNIacLaurin, the President of the Section : — (1) " That this Congress urges upon the notice of the different Governments of Australasia the necessity which exists for fresh legislative enactments in all the 32 INTERCOLONIAL MKDICAL CONGRESS OF AUSTRALASIA, colonies, with a view to obviate the grave dangers to public health which every- where prevail, and which in many cases are due to easily removable causes." (2) " That in the interests of the public, this Congress urges upon the various Governments of Australasia the necessity for amendments in the lawr. relating to the position of medical i^ractitioners, in order that the public may be in a position at all times to protect themselves against the impositions of unc^ualified persons.'' (8) " That copies of these resolutions be forwarded by the secretary to the Federal Council, and also to the Governments of the different colonies." Dr. Morgan (Newcastle, N.S.W.) seconded the motion, whicli was carried unanimously. The General Secretary reported that numerous lettei-s had been received from leaders of medical thought in Europe and America regretting their inability to be present at the meetings of the Congress. VOTES OF THANKS. Dr. Verco (Adelaide) said that an imperative duty yet remained ; the Session would be incomplete if it were not performed ; and accordingly, it was an honour and a pleasure to propose a vote of thanks to the President, Mr. EitzGrerald. It was evident to visitors from the other colonies that Mr. FitzGei-ald was the idol of the Victorian practitioners, and all visitors would agree, after the experience of this Congress, that the idolatry was deserved. He therefore moved that a vote of thanks be tendei'ed to Mr. FitzGerald for his Presidency over this Congress. The Hon. Dr. Taylor (Brisbane) said he had much jileasure in seconding the vote of thanks. He had received from Mr. FitzGerald personally every courtesy and kindness, and he believed that every member of Congress could say the same. The amount of labour which the President and the Executive Officers must ha\'e bestowed in bringing this Congress to so happy an issue could be appreciated only by those who had experience of such undertakings. Undoubtedly, the Session had been an unqualified success from beginning to end. All members would leave Melbourne with feelings of com]ilete satisfaction, and with gratitude to the President for the way in which he had fulfilled the duties of his higii office. The motion was supported by representatives of all the colonies, and was carried by acclamation. The President said he sincerely felt the kind remarks which had been made concerning him. If he had done anything in a small way towards the success of the Congress, he should feel more than compensated by the presence of so many able men. He was not accustomed to the duties of the chair, and he owed much to the forbearance and goodness of the members of the Congress, The Hon, Dr. Creed (Sydney) proposed a vote of thanks to the General Secretary, Professor Allen, for his invaluable services. The work which he had done would have been overwhelming to anyone less capable. Nothing had gone wrong. No other man could so thoroughly and so efficiently have filled the i)osition. All members must join in wishing Professor Allen long life and prosperity, and hope to see him president of some future congress. As time was pressing he would join in the same vote of thanks the names of the Chairmen and Secretaries of the Sections. VOTES OF THANKS. 33 Dr. J. Davies Thomas (Adelaiile) said it Avas unnecessary to emphasise the claim of Professor Allen upon the gratitude of members. For a long time before the Congress was inaugurated, he had been working unceasingly to ensure its success. The President referred to the enormous amount of pains and trouble which the General Secretary had taken. Speaking generally, the whole work of the Congress was on Professor Allen's shoulders, and to him its success was laigciy due. The motion was put and carried unanimously. Professor Allen said : — 'Mv. President, Dr. Creed, Dr. Thomas, and Gentlemen, — -I thank you very much for the kind words which have been spoken, and for the kind way in which you have received them. If, unwittingly, in the press of business I have by any neglect given oftence to any members, I express my sincere regret. I cannot properly acknowledge your kindness ; but I shall have much pleasure in conveying your thanks to the officers of the Sections. Votes of thanks were also accorded to the members of the various Committees, to the hosts who had entertained the Congress, and to the Chancellor and Council of the University for their kindness in placing the University l>uildings at the disposal of the Congress. ADJOURNMENT OF CONGRESS. On the motion of Dr. Verco (Adelaide), seconded by Dr. Brgwxle.ss, it was resolved that the Congress sori)tion of the hyperplasia and in rendering the organ less sensitive and painful. It is most gratifying to know that this class of diseases is at length likely to become amenable to treatment, and that tlie unfortunate victims of uterine troubles are likely to be saved by this means from the unsatisfactory and painful methods of procedure hitherto in vogue. And who can foretell where the use of this agent in the treatment of diseases will end ! So with animal electricity or magnetism. At present relegated to persons having little or no scientific knowledge, the time will, I believe, soon come when its use will be clearly demonstrated by some member of the profession. Already it has been proposed to use hyi)notisni in midwifery, and in France it has been actually employed instead of chloroform in such cases. The physician is called upon to treat many, diseases resulting from over indulgence in alcoholic stimulants, and he is brought into frequent contact with those vices which owe their origin to habits of drinking. Insanity is a common result of these habits, and our lunatic asylums contain many examples of such cases. It is not to be supposed that the medical ])ractitioner should become a temperance lecturer, but he may do much to stay the r;ipid progress that is being made in the habits of intemperance, which lead to such sad results. In these colonies where wealth is so easily obtained, and where the pursuit of it occupies so much time, to the exclusion of the cultivation of a taste for art and science, time is apt to hang heavily on the hands of those who, having acquired riches, or having inherited them, find no necessity for occupying their minds with business, and so are apt to indulge in habits of drinking from having nothing absolutely to do. The following aj)pears among the editorial notes in the Lancet of December 24, 1887 : — " We have lately remarked with pain on the drinking habits of some of our colonies, notably New South Wales. A Iloyal Commission has been occupied for many months in taking evidence on this subject, and arrives at conclusions which should excite the concern of every inhabitant of the colony. The premier colony has the distinction of drinking more intoxicating drink, and that of a worse quality, than almost any other English-speaking community in the world. This is a bad distinction, which the following figures seem to 40 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. confirm. The drink bill of the United States per head is £1 13s. 6d. ; of New Zealand, £3; of the United Kingdom, £3 7s. lOd. ; of Victoria, £4 13s. lid.; of New South Wales, £5 14s. In the city of Sydney alone, there are said to be 3000 persons known to ]je habitual and absolutely hopeless drunkards. We are informed that not only does the colony drink more than other similar communities, but that it drinks much more than it did twenty years ago," &c., &:c. It is a great pity that our universities are not more attended by the youth of these colonies, for it is only by that higher education which induces an inclination for science, art, or literature, that any real stand can be made against the evil mentioned, an evil which is ever growing with increased wealth and population. In the mother country, where a university career affords a certain social distinction, it is very much the practice for the wealthy to send their sons to college, where if not veiy much is learnt by the student, he is brought under restraining influences and a certain amount of discipline, at a period of life when habits are more easily formed, and the mind more readily bent than at any other time. It is our duty as medical practitioners, having by reason of the nature of our profession opportuni- ties of coming into close contact with the inner life of the community, to endeavour to point out to parents the advantages which accrue from a University career, and the dangers which such a career may save their sons from. In the mother country wealth brings with it certain responsibilities, the neglect of which condemns the individual to social exile, and that, in a country where the struggle is as much after social position as after wealth, is regarded with feelings of dismay. A social system, which makes such strong class distinctions as that of Great Britain and Ireland, is not to be thought of here, and no one having the well being of the community at heart would wish to see such established. What we should aim at is to create an aristocracy of intellect, the passport to which would be a cultivated mind, and a high sense of duty to one's self and one's fellowmau. It should be our aim, therefore, to encourage any movement which may have for its object the promotion of means for furthering the higher education of the youth of both sexes, and for enabling those who may display an inclination for scientific and literary pursuits to follow out their desires to the fullest extent. In all walks of life may be foimd genius, talent, and a high order of intellect, and it should be our aim to bring about such a state of things as will enable the son of the humblest member of the community to cultivate the talents with which God has endowed him. Genius and talent are as much the proi)erty of the whole community as of any one individual member thereof, and it is as much the duty of the community to cultivate that genius and talent, as it is of the individual himself. 1'KKSIDENT's address — SECTION OF MEDICINE. 41 The part which bacterial orgunisius play iu t]>e production of disease is daily becoiuiiig more clearly understood, and the time is, I lielieve, fast approaching, when our knowledge of thehal)its and life history of micro- parasites will enable us to mitigate, if not to prevent, their pathogenic action in the human being. Already, it has been pretty clearly demon- strated that certain diseases, suchaswoolsorters'disease, malignant pustule, any, tinea ioneers in this l)ranch of knowledge ; but sufficient lias been done by Lewis and Cobbold, now retired to their rest, by Manson and our .South American investigators, still struggling with a difficult ])roblem, to encoui'age our youthful naturalists to work at the subject of blood-parasitism, not merely as it afflicts the human race, but in the wide tield of animal life, as there can be little doubt the more extensively the work is prosecuted, the clearer will be our views as to the measures necessary for human sanitation. The sul)ject after a time becomes an interesting study, more fascinating, if possible, than diatomes, and is intimately bound up with the welfare of ourselves and onr animal friends. Few things fill the mind with greater surprise than the discovery that the heai-t of our faithful dog is so tilled with worms that his life cannot be exjiected to last long. <3n examining a drop of blood of a dog, we can ascertain by the presence of tilaria? whether such is the case ; and if we find it necessary to sacrifice our servant, we shall discover in the right side of the heart, and in the pulmonary artery, worms from four to ten inches long, more or less, interfering with the circulation of the blood, leading to dyspnoea, fatness and dropsy. Filarise, whose embryos float in the blood, may in all cases require the intervention of some blood-sucking creature to assist in their distribution, mosquito, sand-fly, louse, or Hea, all of which will need to be examined. With regard to the dog, the study of which is very convenient, as he is always at hand, nuicli information has yet to be got. Some years ago, I found the louse of the dog with its meal of Ijlood, and in the Ijlood the emljryos of Filaria immitis. This information was connnunicated to the Queckett ^Microscopic Club by Dr. Cobbold in February 1880. Dr. B 50 INTERCOLONIAL MEDICAL CONCiRESS OF AUSTRALASIA. Prospero Sonsino, of Pisa, wliose researches on blood parasites in E^ypt are so well known, in a recent letter reminds me of the com- munication, and is anxious to gain any further information obtainable in our country with regard to this iilaria. The dipteron Stomoxys calcitrans also absorV>s with the dog's blood the embryo worms. Of these, I once counted tifty-nine in one insect. Tiie stomoxys-fly, distended with blood, it is not difficult to capture on sunny walls. It may be distinguished from the common house-fly by the set of its wings, more divergent })Osteriorly, and lying Avitli their tins resting on the wall. When captured, the sharp penetrating beak at once contii-ms its generic title. These flies are a great annoyance to horses in summer, gorging themselves with their blood, but I never found fllaria? taken up, except in the instance referred to, and then T had seen the fly feed on the dog. Dogs clean themselves of fleas and lice by biting, and so probably acquire the parasite; they frequently also snap at flies. Feeding exj)eriments with various insects, containing blood, are however wanting, to trace the life history of the parasite; and from careful scrutiny, knowledge may be gained that would be of the greatest help in understanding what is wanted to arrive at the history of the human filaria. The embryo of F. immitis has no sheath, and is niore active than the embryo of F. sanguinis hominis. In dissecting dogs known to have embryos in their )>lood, the ]>ortal cii'cnlation should be searched, in case the jiarent worms, not being found in the heart, are obstructed in their ]jrogress by the cajnllaries of the liver. When F. immitis is extracted from the heart, and placed in a vessel of blood or blood-serum, it writhes about with a slow motion, and as the coils rise above the level of the li(|uid, they api)ear pure white, as if greasy, A dead or injured worm rapidly becomes stained red. The worms have much rigidit}- while alive, and at times cause the death of their bearer, by rupture of the ventricle when hunting. There is no history of the tilaria of the dog living in the human subject. I have examined the blood of many dogs belonging to the aborigines of this colony, but failed to find the parasite.* It has yet to be deter- mined if the embryos of F. immitis observe the i)eriodicity in activity, shown by Manson to obtain in F. sanguinis hominis. In the sheaths of the tendons and burs.ie, about the knee joint of the great kangaroo, theie are often ibiind worms as large as those in the dog, but not of such rigid textux'e. They are easily seen when the liind-quarters are skinned. The embryos of this worm never, so far as I have examined, enter the blood-\'essels, but are plentiful in the synovial secretions of the bursas inhabited. How the embryos are transferred from their resting place is not known ; but I would expect that the mosquito, probably the large grey sort, has the power of pene- trating into the burste with its piercer. The ease with which the nioscpiito penetrates oiir trousers when tigiit over the knee, would indicate the possibility of this being the case, as the kangaroo sits with the integuments tense over the knee joint. The })arasitic fly, that lives among the hair of the kangaroo, may ^ilay some part in the life history of this worm. None of the smaller species of kangaroo in this neighbourhood have any worms near the knee. * Since found in the blood of blackfcUows' dogs, June 1889. ox FILARIA. 51 I have often lieard it mentioned that fishes in some parts of Anstralia have worms in their flesh, and that after cutting a fish in pieces, and leaving them on a ])late all night, the worms may be found crei)t out of the muscles in the morning. I have not seen an instance of" this parasite, but am told that fresh-water fishes near Melbourne are so ati'ected. >Some student at your University might undertake the inquiry. The resting place of the mature filaria in the human body is hard to determine. It is found in the lymphatics of the arm ; there, dying jirobably from bruises or the excessive muscular action of the labourer, it forms an abscess, the structure involved becoming brawny and tumid. liigors mostly occur. If the abscess is opened early, the parasite may be percei\ed, more or less broken and undergoing disintegration; the embryos, also dead, escaping from the ruptured ovarian tubes. The particulars of tlie discovery of the first parent filaria sanguinis homini.s, were published in the Proceedings of the Pathological Society of London, in Vol. 29, A.D. 1878, but as access to this work is not easy, I will repeat briefly some of the cii'cumstances. In this colony, the embryo worms in the blood were first found in Ipswich by the late Dr. Thomas Powlands, by following the researches of Lewis, of Calcutta. Dr. Jno. Mullen was the first ])ractitioner to discover a case of chyluria in Brisbane. A case of cjiyluria happened to l)e under my care when Dr. Rowlands informed rae of the observations of Lewis. This was in December 1874. A few days later I observed the parasite in my patient's blood. Specimens in blood and in glycerine were sent to Dr. William Roberts of Manchester, in 1874, and subsequently in 1875, with a request to interest Dr. Cobbold in the inquiry. Dr. Cobl)old examined the tubes of blood in May 1876, and published this .statement: — "There cannot, I think, be much doubt as to the identity of all these sexually immature nematoids." — See British Medical Journal, June 24, 187G. ' I received this on September 28th, 1876. Then there must be a parent worm to be found, but where '? Reading up the history of filaria medinensis, of which I had no practical acquaintance, it is recorded that Guinea-worms, when not extracted with care, form abscesses. I had by this time found several cases of filaria disease, and had gathered some record of those patients sufiering from abscesses. I resolved therefore, on receipt of Dr. Cobboki's communication, to carefully examine all abscesses my patients might have. This I did, without finding anything until December 21, 1876, when I opened an abscess in the arm of a youth emi)loyed as a butcher. I collected the matter as usual in a small vessel. As a preliminary inquiry, the blood had to be inspected for embryonic fllarise. This was the second case in which the blood contained the pai'asite in question, but in the former the abscess, which was an old steatoma, gave negative results. On examining the matter in the present case, a thread-like body came in view. Under the microscope it was without doubt a worm, and embryos were seen coming out of its body. E 2 02 INTERCOLONIAL MEDICAL CONCJHESS OP AUSTRALASIA. On March 21, the following year, I tapped a liydrocele, in an elderly patient. M'ith a trochai- and canula combined, which I had raade by McLennan, our siirgical instrument maker. On withdrawing, a lash of hair-like bodies was caught in the eyes of the instrument. At once suspecting their real nature, I ])ut them in the hydrocele fluid, when they began to move about with great activity. Embryos in abundance were found in the hydrocele fluid, and in the patient's blood. jNIy friend. Dr. Mullen, I sent for to see the live worms. I kept them for over a day, during which time they remained entangled. On immersing them in pure water they ntretched out and became quiet, on restoring them to the hydrocele fluid they recovered their activity. Uncoiling them in fresh water occupied me over an hour. The specimens were now transmitted to Dr. Cobbold, with a communication, which appeared in the Lancet of July 14, 1877, ]). 70. In the Lancet of September 29, 1877, Dr. Timothy Lewis records dissecting an elephantoid tumour, lemoved by Dr. Gayer, on August 7 of the same year, from a young Bengalee in Calcutta, and after eight hours' search discovering in a blood-clot the adult tilaria, thus verifying my belief, previously published, that the tilaria would prove to be the cause of such growths. In the Lancet of October (5, 1877, Dr. Cobbold's drawings of the parasites transmitted from Australia appeared, showing the sexual organ of the female pai'asite. jNIany adult fllariaj have since been found, but recently Dr. Pedro S. de Magalhaes has kindly sent me an account of two parasites having been found by Dr. Saboia in the right side of the heart of a boy who died in the Hospital Misericordia of Bahia. The disease from which the patient died is not mentioned. The worms are very ably figured, after comparison with the drawings of Lewis and Cobbold ; one is a female, the other a male, the latter having a spiral tail similar to that of Filaria immitis. This is the first time the male parasite has been described. Dr. Magalhaes also draws a peculiar band running along the body of the female, an appeai-ance recorded in my lirst unpublished drawings. I have also among them the sexual organ of the female, near the head, the significance of which was not apparent to me when the drawing was first made. I have to thank Mr. Birkbeck of the Railway department for aid in translating the Portugese — Gaidci Medica da Bahia, No. 3 de Setembro de 1886; also jiaper on the same by the Faculty of Medicine of Eio de Janeiro, No. 3, 1886. The ])athological conditions produced in the human subject by filariaj are numerous. The movements of the embryos in the blood do not appear to inflict injuiy. Dr. Manson has studied this subject with great care, and showed the further development of the embryos in the intestines of mosquitos — see Linnccan Societijs Transactions, March 1884, and in previous i)apers in 1877 and 1878 — also the greater activity of the embryos in the evening. Dr. W. W. Myers, of Shanghai, shows that the normal evening rise of temperature of the human body may account for the greater activity of the nematoids. How the parasite })asses from the mosquito to the human subject lias not been satisfactorily traced, though it is likely that it is drunk in water. ON FILAHIA. 53 The fact that few cases of youth suffering frou\ fihxria in Brisbane are now to be found, seems to show that the city water suj^dy is purer than tlie well and tank water foruiei-ly used. The new cases presenting themselves in Brisl>ane are from country towns, where there is no public supply of drinking-water. The adult jiarasite probably, by its presence in the lymphatics, blocLs them up, either by its own bulk, or by the inflammation it may cause. If located in the heart and blood-vessels, as in the Bahia case, thrond)Osis and embolism may happen. Little information is to hand on this point. When the parasites live in a hydrocele, no harm can follow. i\Iy i>atient, whose hydrocele contained four worms, was not free from embryos in his blood for years after, showing that all the adult worms weie not removed from his body. 8ui>pose the parent worms are in the structures of the arm, a common occurrence, the disease manifests itself, and is recognisable, by rigois and abscesses. Cases that sutlVred in this way are now in fair health, others are weakly, but able to work with feeble circulation. Elephantoid growths and limbs do not develope in Brisbane. It is not easy to account for this. People are better fed here than in India, and the climate may be more salubiious. One patient here has intense scleroderma of the head, arms, and upper part of the body ; but now, after some years, the skin is becoming softer, and embryos are no longer to be found in the blood. How could the lymphatics be blocked with adult parasites, so as to cause this hardness of the integuments of the head and shoulders? Chyluria and elastic tumours in the groin are associated. When the tumours are evacuated, an operation not easy of execution, as the sac is very difficult to pierce by tiochar, they yield chyle, containing a very small amoinit of blood, which deposits itself in the bottom of the receiver after some hours. The blood is very bright, and seems to differ from ordinary blood. May it be blood in a state of development? Wlien urine becomes chylous, the elastic tumours, if present, lose their tension. These elastic chyle-sacs, emptied of their contents and injected with iodine, will solidify and close up. It is rather a perilous operation, as the sac is partly intra-abdominal, and there is danger of peritonitis. A patient, cured of these tumours by injection, afterwards suffered from chyluria. A better course is to use a double truss, with concave pads. A case so treated is now cured, and no embryos ha^'e been seen in the blood for two years. Chyluria is sometimes so severe as to threaten death from exhaustion. A chyluric patient was confined of a living child, the chyle and blood discharged from the bladder was in great abundance. She became so weak as to faint on the head being raised. Hiemostatic remedies did no good. A fatal issue being antici})ated, I injected the bladder with tartrate of iron and port wine. After two injections, the discharge ceased and the patient recovered. Lymph vesicle on the skin of the leg or scrotum seems related to chyluria. The lymjih discharge is intermittent, so is the chyluria. At times it is scarcely possible to tind the minute aperture on the scrotum which discharges the lymph. From this I had one patient die, with ('pistaxis and frequently recurring rigors. It seems to me that in chyluria 54 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. the aperture which gives out the chyle is a lymph vesicle on the walls of the bladder. It would be difficult to verify this conclusion, even post mortem, and the presence of parent worms among the pelvic lym})hatics would be hard to find. At the Medical Schools of India it ought to be possible to obtain bodies of patients, known to suffer from tilaria diseases, for their dissect- ing rooms. Preparations, showing the enlargements and varicosities of the lymphatic system, could thus be made, tracing to their true cause; these abnormal conditions. BERI-BERI AS SEEN IN THE NORTHERN TERRITORY OF SOUTH AUSTRALIA. By Dr. Percy Moore Wood, Palmerston, Northern Territory. As I have reason to think that this is probably the first time that attention has been drawn to this disease in Australia, by one who can speak from personal observation, I trust this short j)a})er may not be without interest to you. Owing to the great difficulties under which I have laboured, such as visiting the patients in miserable huts, the patients l)eing oft-times very ])Oor, and nearly always destitute of any knowledge of English, the interpreters too being often grossly inaccurate ; the distance from medical centres of knowledge being so great as to preclude the chance of keeping up with the latest investigations of this disease ; the insufficiency of ward space in the local hospital, preventing me from taking in any but the very severe cases ; and finally, the rapid decomposition that takes place in this climate, preventing any satis- factory microscopical work by a bus}' man ; I am aware tliat what I write may, in a measure, lack the seientilic value it would have had if circumstances had been different. The authorities that I have with me are Dr. Maclean, on '• Tropical Diseases;" Sir Joseph Fayrer, on " Beri-Beri " in '• Ouain's Dictionary of Medicine ;" and Dr. Broadbent's edition of Dr. Tanner's " Medicine,'' a short account of this disease from the ])en of Dr. Aitken. History of the Disease. I have reason to think that it was during the years 1870 and 188() that this disease first became endemic in the Territory, as, on referring to the death register book, 1 notice that a great many deaths were during that period registered under the headings of dropsy and paralysis. These deaths all occurred among the Chinese, who were young men. generally under thirty years of age, and never seen by a medical man, but the record of death was simply given to the Registrar officially by a trooper. The place where these deaths chief!}' occurred was Pine Creek, but some apparently took i)laoe at Palmerston. This o[)iniori is strengthened by the fact that I have shown some of my patients to Europeans, who were resident in this country during 1879 and 1880, BtKI-niCHI AS ,S1:KN in THK XOHTIIERN TEinUTORY, i)i) and they think that the cases look siniikir ; but what apjtears to strike them most is the way that the convalescents at both outbreaks walk. About two years ago, there was a small but fatal outbreak of this disease in the gaol here, among the aboriginals. Seven were attacked, three severely. Of these, two died ; the re.st recovered. The reason I mention this occurrence is, that a few weeks before, the aborigines had been placed on Chinese diet, which means rice instead of bi-ead, and half the quantity of fresh meat, and during that time there was a scarcity of fresh potatoes. The Chinese did not sutler at this time, and in fact throve very well on the diet allowed them in the gaol. I could find no other cause but the change of diet, so replaced them on the Eui'opean scale, and as soon as ])ossible gave them fresh English ))otatoes, and they were soon in good health again. There is another circumstance, which occurred during the years 1879 and 1880, and this year, namely, malarial fever was very prevalent, and several deaths were returned during the former yeai'S from that cause. This year, hort-ever, no death has been returned from among the Eui'opeans from this cause, but a few undoubted cases have been found among the Chinese, owing, I think, to the fact that they have not come under treatment early enough ; but here we must not forget one thing, namely, that Euroiieans badly attacked with malarial fever generally leave the Territory. During my residence up here, I have had one fatal case of pernicious anosmia in a European, vet. 4-6, who died in, the hospital during August 1887. I should not have mentioned this case, had I not noticed that Sir Joseph Fayrer, in '• Quaiu's Dictionary of ^ledicine," page 106, on 13eri- Beri, writes: " Possibly, iiernicious ant>3mia in Europe is the same disease."' The notes of this case do not resendjle in any way beri-beri ; it simply ran the course that cases do in England. From what I have so far seen of this disease, it well retains its character of being a very fatal one. I have had under treatment about forty cases, and twelve deaths have been recorded ; but I have good reason to believe that about tifty more deaths have occurred. What percentage of deaths this really gives, I don't know, as I am unable to say whether they kept among themselves cases that eventually recovered ; a few I feel certain were so kej)t, but how many I cannot learn : I rather think that probably the majority of the subacute cases came under my notice, owing to the fact that as the local hospital was unable to receive them. Dr. Stow, the Medical Officer in charge of the railway works, supplied them with food and medicines at their own homes, and this made them very ready to apply for assistance. It is with pleasure that .1 may here report, that no cases of Beri-Beri have so far occurred among the Europeans resident in the territory. Causes. According to authorities, I suppose I should commence with (1) Malarial climate ; (2) Tropical tem])erature ; (3) Propinquity to the sea ; (-i) Wet season ; (-o) Bad feeding. (1) What the first cause may be, primarily, I cannot say. I suppose, malarial fever being veiy jjrevalent in China, a great many of the Chinese have ])robably suffered from it; but it is not necessary to be in a malarial climate to have Beri-Beri, as is jiroxed by tlie fact, 56 IXTERCOLOXIAL MEDICAL CON'GRESS OF AUSTRALASIA. that Chinese crews, sent to Iv'ewcastle-on-Tyne to Ijring out Chinese men-of-war, there developed an outhre:ik of this Bevi-Beri among tliem. (A short accoiint of this outbreak is, I lielieve, to be found in Braithwaite's " Retrospect of Medicine " for either last year or the preceding year.) Moreover, in nearly all the cases that were under my observation, there was no previous history of malarial fever. (2) Ti'Opiccd Temperature. — Though this disease has generally been known only in the troi^cs, the outbreak of it at Newcastle-on-Tyue shows that it is not absolutely confined within these limits. (3) According to Dr. Maclean, this disease is most prevalent near the sea, generally within 50 or 6(1 miles. The cases that I have personally noticed have never been less than 7o miles, some 05 : and, if I am right as regards the cases in 1879 and 1880, they chiefly occurred at 145 miles from the sea, and at an elevation of about 700 feet above low water level. (4) Wet Season, — Undoubtedly tlie majority of my cases were deve- loped towaixls the end of the wet season, but I have just seen a case, and a very severe and well-marked one, that has been recently deve- loped, and no rain has fallen for the last five montlis. (5) Bad Feedinr/. — In all cases that I have had under my care, the patients give the same answer to the question — What has been your diet? Answer — Rice and salt fish. In one case, that had nearly recovered, the answer was — Rice and salt eggs. In every case there was a marked want of fresh meat and vegetables. That the majority of cases occurred during the latter part of the wet season was due, as far as I could make out, not to excessive exposure to the wet, but to the fact that the wet made the roads impassable, so that fresh supplies could not easily be brought ; and this was important because, where these camps were, during that time, the country immediately around was not able to sujiply the number that required fresh food. It was also a noticeable fact that all the jiatients (with three excep- tions) had only been in the Territory from twelve to eighteen months, and all were young men under thirty years of age, many under twenty years, obviously those most likely to come off" badly in bargaining for articles of diet, not knowing the al)solute necessity for obtaining them. In conclusion, as to cau.se of disease, I cannot help thinking that, for want of a better term, it is a scorbutic condition in a rice-eating race, probably influenced by a tendency to nialaria : — (1) High temperature is not required, as the outbreak at Newcastle- on-Tyne proved. (2) All cases, as will be seen further on, had a large si)leen, though certainly not what I call a malaria one. (."5) I think cases occurring 150 miles from the sea, can hardly be considered as due to coast influences. (4) The wet season, I have shown, is not necessary to jiroduce it. (5) As 1 have shown, all cases that I have had jiersonally to do with, have been fed badly. I have reason to understand, that the outbreak at Pine Creek was chiefly amongst new comers, who were badly paid, and ill-fed ; and I have previously shown how disastrous rsEni-HKin as skkx in 'iiik \oin iii;i;\ Ti:i;i!iroHV. ;>( the rice diet was, ai»i)ai'ently, witli the aborigiues of Australia in the fjaol here, and how heueficial was the cliango to the Kiir(»j)eaii scale. Though I have called it a scorbutic affection, I have to admit that I have never seen spongy gums, il-c. ; hut there is one constant symptom, namely, pain in the muscles, and chiefly in those of the Ciilves ; l)ut they do not hecome hrawny and hard from the deposition of any infiaiiimatory material. Symptoms. Tliese occur in two forms, acute and sub-acute ; Init, as in all diseases, the}- frequently pass into each other ; the acute, [)erhaps, easily becoming subacute ; the sub-acute more frequently becoming acute. Aa'tc. — Patient feels ill, and couqilains of great heat in his epigastric region ; he seems to rapidly lose the use of his legs, so that he cannot stand (l>ut can move them moi-e freely in bed), and he complains of intense pain in their muscles, which, on account of the want of tonicity, appear a-dematous. He rapidly becomes very Ijreathless, cardiac action being very quick, and tiiere is always a soft bruit, which appears to be more h^emic than anything else. The legs then become tedematous, and, in fact, general anasarca ra|)idly counnences, which ajjpears to cause acute pain, especially in the lumbar region (lumbar cushion frequently well developed), and if the patient lives more than a few days, he has the appearance of having acute Blight's disease ; but I have never seen the scrotum swollen. He becomes very restless, the face assumes a very anxious expression, the tongue becomes brownish-black, sordes collects about the teeth and li[)S. Eespirations become quicker and shallower ; cardiac action is so rapid, that the pulse cannot be coinited. He assumes the sitting ]>osture, keeps moaning, and dies suddenly, some- times crying out, as if in intense pain, Init he remains sensible almost to the last, and frequently will take liquid food up to the same period. In one acute case (fatal), marked jaundice existeil. I have never found eithei- albumen or blood in the urine ; nor is thei^e any great (if any) diminution in the quantity; sp. gr. generally about 1020. There is generally no great jiyrexia ; tenqierattu'e frequently only about 99\ tSome cases only last about 4S hours ; one case only lasted 26 hours. Post-mortem examinations show generally the blood to be in a very watery condition, and with a strong tendency not to coagulate, especially in Aery acute cases. The nniscles are pale, and look sodden with a yellowish serous fluid ; sonietimes this colour is very marked. Lungs extremely cedematous, and generally a small quantity of Huid in the pleural sacs. Pericardium. — -This sac I have seen distended with Huid, but in the majority this was not the case. Muscular tissue of the heart, pale and flal)l)y. There were ali''a>/s ante-mortem clots, sometimes very large, extending into the blood-vessels which pass from this organ. The other blood was dark, and had generally a granular look, with a treacly con.sistenc}-. In only one case did I find valvular mischief, and that was mitral. This appeared to be old standing, and was from the body of a Tamil, the only one of his race that suffered out of l."iO working on the line. I attribute the fact of his suffering from tills disease indirectly to his cardiac affection. As he was not conqietent to do his work, he became badly j)aid, hence badly fed. Chinese have a great antipathy to post-mortem examinations, especially 58 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. if tlie head is opened, so I had iu many cases to respect this feeling ; but in the cases in whioli the head was opened tliere was alwaj's a marked increase of cerebro-spinal fluid. Brain otherwise healthy ; cord not examined. Abdomen. — Liver generally healthy and firm. Spleen considerably enlarged, soft, and of a kind of maroon colour. Kidneys large and cedematous, otheiwise healthy looking, and capsule easy to remove. Su]n-a-renal capsules, when found, healthy. There was also a collection of serous fluid in the peritoneal cavity, but not very excessive. Sub-acute Symptoms. Patient feels pain in the ej)igastric region, with a sensation of heat, rapid cardiac action, which evidently is the cause of great anxiety to him ; muscular pain in the legs, which rapidly lose their power, so that in a few days the patients are quite incapable of standing. The extensor muscles seem first afl'ected, then the abductor and adductors. This muscular pain is intense, so that they shrink when you ])UC your hand near ihem ; but the skin does not seem tender, and at first, there is no want of sensation. The legs seem cedematous, but only, as in the acute cases, from the want of tone in the muscles. The muscles of the arms may become affected, and assume the appearance of wx'istdrop, with verv little power in the flexor tendons. In one case, the vocal cords became affected, and the voice rendered falsetto. I have never seen complete paralysis in the extremities ; all cases have been able to move theiu in a limited degree, and T think that the psoas and iliacus have never been paralysed, as I also think that the deltoids do not become so. The legs become ffiJematous after about 10 days, and then the skin appears to become numl). I have never seen the ui)per extremities iu that condition, unless the case is assuming the acute form. If the ])atient is going to get well, he may remain in this helpless condition for some time ; and if he sits up, in the Chinese fashion, which is squatting, or rather squatting fashion, for he sits on his haunches, his legs ])ulled up towards his abdomen, the legs beconie intensely cedematous. They may then gradually improve ; the arms move first, then the legs ; the extensor muscles seem the first to recover. While so ])aralysed, there appears to be no electro-contractility, either to the continuous or interrupted currents. When they are first able to stand, their attitude is very characteristic. They all appear to feel that the knee-joint will give way backwards, and appear to want support in their popliteal space. When commencing to walk, they use a stick, and gi-asi)ing it with both hands, lean forward, drawing their legs after ihem, keeping the knee stiff". The improvement is slow, and generally three to four months elapse before they can walk well. When these sub-acute cases are fatal, they die in the same way as the acute cases ; in fact, they ;ip))ear to develope acute symptoms, and they may do this some weeks after ti'ey appear to be doing well, but why, T cannot explain. I have sometimes thought that this, again, is due to want of food, not because the i)atient had not got it, but because, being sick for so long, unless he had plenty of cousins, etc., it was difficult to get people to cook for them, and I fear that, even when they were getting it cooked, they were ])aying for it, by giving away a ])art of their food. I have never been able to jnake a post-mortem in\estigation of one of DISEASES OF POLYXESIAXS, AS SEEN IX QUEENSLAND. 59 these cases. The muscles waste enormously in this class of cases; but I am unable to say how long it is Ijefore tiiey are able to return to work, because they generally go back to China. Prognosis. This is, as far as I have seen, very unfavourable. I have never known a ]iatient recover, when breathlessness set in, either eai'ly or after a few weeks' treatment. The i)atient then generally dies within tifty- six hours. Treatment. This being a disease of (for want of a better term) a scorbutic nature, fresh vegetables, especially English potatoes, and fresh meat are abso- lutely necessary. As regards drugs, my colleagues, Drs. Bei'ill and Stow, and myself have learnt to place great confidence in one, namely, digitalis. This drug, combined with iron, we have found very beneficial, and if this con)bination produces too much constipation, we combine it with ammonia and cinchona. The patients find the benefit of the digitalis, and frequently notice its absence if omitted by saying, " This medicine not all the same as the last; this one no good." How it acts I do not know, but I think its value is primarily due to its controlling power over the heart, and then, jjcrhaps, to its action as a diuretic. This paper is written with the full knowledge of my colleagues, and if digitalis is found to be of any service elsewhere, the credit is due to the observations of Dr. Berill, as he first gave it. I am further in- debted to Dr. Berill for the great assistance he gave me in making the post-mortem examinations, as he frequently made them uuder veiy trying circumstances. DISEASES OF POLYNESIANS, AS SEEX IN QUEENSLAND. By F. BowE. M.B., Maryborough, Queensland. In this paper, I shall endeavour to draw your attention to a few points, in which diseases in Polynesians differ from the usual type. In the first i)lace, disease is not accompanied by the usual amount of pain and distress. For instance, one day I was surprised to see a boy with j)neumonia of the right apex, with a tenqierature of 105°, sitting by the tire in a ward, smoking a ])ipe ; and altliough this is an extreme instance, yet, in the early stage of [)neumonia, few would remain in bed, unless ordered to do so ; they would sit by the fire in cold weather, and on the verandah, or in the i)addock, in warm. Yet, the type of the disease, taking the tenqierature as a guide, is quite as acute as in European races. In phthisis, too, the cough does not seem to distress them much, and they generally manage to get about until within three or four days of their death. In dysentery, you seldom see an expression of pain on their features, although this is a most painful complaint. This insensibility to pain must not be attributed to stoicism, as their GO INTEHCOLOXIAL MEDICAL CONCiRKSS OF AUSTRALASIA. disiiosition is anything but tliat. Tliej strongly oV)ject to the pain of H mustard plaster, and the sight of a lancet causes great disma}-, and an incision is generally accompanied by a cry. These latter facts are not what you would naturally expect — ^incisions of the skin by means of a piece of glass form one of their native methods of treatment, and my patients often arrive at the hosi>ital with a number of cuts, very like those made by a cupping instrument, over the forehead, breast, or side, wherever they have been experiencing ]>ain ; and when being tattooed with a couple of pins tied on to the end of a stick, and some blacking, they appear perfectly comfortable. I may mention, although this is not now-a-days considered a surgical operation, that they can shave very well indeed with a piece of broken glass. As an instance of their great objection to any incision, I have seen a man with whitlow die from pysemia. When I first saw him, he had an ordinary whitlow of a foretinger ; he refused to have it incised, and went away. He came again a week afterwards, when the back of his hand had become very much swollen, but still refused either an incision, or to come into hospital. He was finally admitted, aV)out ten days afterwards, in a sinking condition, and died in a couple of days. At the post- mortem, I found that the pus had burrowed nearly as high as the elbow, and there were pysemic abscesses in the kidneys and lungs. They generally neglect their whitlows, and I have had to amputate a finger or a thumb on several occasions for it. Another thing you notice, is the way in which these boys are able to retain their appetite for solid food. Patients with high temperatures, and when sutlering from acute disease, will dispose of their ration of beef (fib., including bone, really i lb.), and a piound of bread. Tuberculous patients retain their appetite a long time, and wben it fails, they can still manage to eat potatoes, which they often appear to consider a luxury. One might argue that a liking for milk is an educated taste, from the fact that Polynesians, on their arrival in the colony, Jiave all a very strong dislike to it ; and when it has been essential tliat they shoidd take it, as in dysentery, I ha\"e occasionally been obliged to give them a few doses of it by the nares. After that, they generally make up their minds to take it. Those who have been in the colony some time, do not apj)ear to have any objection to it. The only disea.se, from which they suffer more distress than white men, is influenza. In this they always complain a great deal of head- ache, for which they often cut themselves, as I mentioned above, and at the beginning of the attack it often ati'ects the lungs very much. There is a great deal of dyspnoea, with rhonchus and n'des, and a high tempera- ture, 103" or 104:° F., and when they are attacked at their work in the field-', I am told that they are often seen gasping for breath, and then they throw themselves down, saying that they are "close up dead" (that is, nearly deail). They generally recover speedily, and I have never seen a death from the complaint. A very striking peculiarity is the occurrence of mania in connection with }meumonia. It most frequently comes on a few days after the commencement of the disease, and it might be regarded as replacing delirium, but against this view it is to be noted that it lasts generally three or four days after the temperature has subsided, and when you would expect any delirium to have disappeared. In a few instances I DISKASKS OF I'OI.VNKSIANS, AS SKKN IN tJUEKNSL.ANU. t>] have noticed tljat it lias made its aj^pearance after the ac-ute stage of tlio pneumonia was over. The mania is sometimes accompanied by a good deal of violence, and occasionally the ])atient will clutch the iron bars which guard the windows of the strong-room, and shake them like a wild animal trying to escape. It does not ap[)ear to be moie frequent with pneuuionia of the a})ex than of the base, which is not what you would naturally t to break out again, when the health breaks down from any cause ; for instance, from tuberculosis. With regard to tertiary .syphilis, I have seen a couple of cases of syphilitic ulceration, or what I took to be such. They had all the usual characters of the affection, but presented no scar, and denied ever having luul a sore, but there may have been an inherited taint. They healed quickly under treatment; bnt I now regiet that I did not try whether they would have done so under strictly local treatment, before combining it with constitutional remedies. A fatty degeneration of the kidneys is present in nearly everv instance in which I have made a post-mortem ; in fact, it is quite exceptional to see a healthy kidney in a Polynesian, and this is frequently accompanied l)y fatty disease of liver, but the latter is not so general nor so extensive as that of the kidneys. I believe that fatty degeneration of the kidneys is not usually accompanied by the changes comprised under the term contracted kidney, but in Polynesians this is always the case, more or less ; the size and weight of the kidney is diminished, varying from 3| ounces to less than 3 ounces (the ordinary weight of kidney being 4^ ounces). The capsule is adherent in places, tearing the substance of the organ when detached ; in other patches, it is comparatively free ; the surface of the kidney is mottled with stellate veins, and is often partially divided into lobes by the contracted portions ; it is seldom, or never, granular in appearance. On section, the cortical portion is generally diminished in thickness to some extent, whitish or yellowish in colour, and the jiyramids healthy in appearance, but not always so. C)n microscopic m^ NECROSIS OF FINGERS AND TOES (Dr. Bowe's Paper.) DISKASKS OF POLWKSIAXS, AS SKKV IN (^l lOKNsLANh. G3 section, the epithelium is seen to contain fatty granule?, and there is a distinct increase in the connective tissue between the tubules, the meshes of which contain a number of small round cells — in short, the appearances of fatty degeneration, plus interstitial nephritis. The existence of this kidney disease, however, does not ai)pear to give vise to any symptoms, or to interfere with the general health. There is no anasarca, frecpiency of micturition, nor albuminuria ; but I have often thought that -its existence might be an explanation of the low-resisting power these Islanders possess against some diseases, dysentery and tyjjhoid fever in particulai'. From the former they die very rapidly, if the attack is severe, and very often from extremely mild attacks, even when carefully dieted and treated ; and on ])ost- mortem examination, the apiiearances of the bowel are quite insutKcient to account for death. I. may add that they seldom derive much benefit from ipecacuanha in large doses. Until a few months ago, T never saw a case of typhoid in a Polynesian ; l>ut in October, a few cases occurred amongst some new arrivals at a I)lantation. It was associated with dysentery, and X'an a very rapid course, two of the boys dying after an illness of about 36 hours, and two who died on the plantation in even a shorter time (under 24 hours). I am informed that with new arrivals in the colony, it is generally fatal within a very short time, whilst those who ha\e been in Queensland a year or two, very often recover. I should now like to draw your attention to the photographs of a Polynesian named Lambar, who is suffering from a disease which is new to me, and about whose cause and nature I have no idea : — 919. Lambar, a native of Motlap, one of the Banks group, about 24 or 25 years of age. Was healthy up to nearly two years ago, when the ends of his fingers became swollen, the skin broke, and pieces of bone came out, and four months afterwards the same process commenced in his toes. He now has the appearance of having suffered from partial amputation of all his fingers and toes. The following is a description of his fingers in detail : — Left thumb is flexed at terminal joint, the last phalanx is shortened to half-size, and it is doubtful whether there is any bone ; it retains the nail. First finger. — The terminal ])halanx has disappeared, and half of the next. There is still a small piece of thickened and roughened nail. On the under surface there is a superficial ulcer, due to pressure from using a broom one day. Second finger. — No nail on this finger, and still less of the second phalanx. Third finger. — Small piece of nail, no terminal phalanx ; the second api)arently entire. Fourth finger. — No nail, the greater portion of the second phalanx gone. Right thumb. — Small piece of thickened nail, terminal phalanx gone. First finger. — A shred of nail, terminal phalanx gone. Second finger. — The nail retained, smaller than natural, and thickened ; both terminal and second phalanges gone. Third linger. — Nail is retained, terminal phalanx gone, the second shortened. Fourth finger. — Scale of nail, terminal jjlialanx gone, the second shortened. The condition of the feet is much the same. The boy appears to be perfectly healthy in every other respect, no loss of sensation. The only l^eculiarity about him is the extreme tenderness of the skin. If he does any kind of manual work, however light it may be, a large blister at once rises, which soon afterwards forms a superficial ulcer. G4 INTERCOLONIAL MEDICAL CONfiRE.SS OK AU.STIJALASIA. MALARIAL FEVERS OF TROPICAL QUEENSLAND. By T. S. Dyson, M.R.C.S , Noniiantoii, Queensland. Prevalence. Malarial fevers aie generally prevalent in Northern Queensland, and are not limited to one ])articular portion of it. We find them on the eastern coast and in tlie (iulf of (Jarpentaria, and in those districts where the dense scrubs with rich soil are found, and also in the low- lying marshy country ; also wherever new or virgin soil is for the first time worked, such as on the Palmer goldfield, also the Croydon, and also where new railways are being formed. This is the case in those districts where malaria was scai'cely or never known to prevail previously. On the Johnstone River in the early days of settlement, before the dense scrub was cut down, malarial fevers were very ]>revalent, and a considerable number of Europeans first employed died tliere, or were invalided in consequence; but as the ground became cleared, so the fevers also became of a milder type and less prevalent. The same also applies to Cairns, and to any other })lace where there is luxurious vegetation and stagnant water, with decaying vegetable matter in it. Malarial fevers are the prevailing sickness in the Gulf of Carpentaria, especially at certain seasons. The jiroportion of fever cases treated in the Burke district hos|)ital to all the rest has been for the past three years about one to four, but this year the jiroportion will be much greater, owing to the men working on the new line between Normanton and Croydon being treated at the liosp.ital. Season. The regular malarial season commences after the wet season is over, viz. from May to September, or that of the south-east monsoon, but cases do occur all the year round. I lind in the Uulf district, that the rainfall atiects this season materially. Should the wet season be })ro- longed and the rainfall heavy, as in 1886-7, when we had about tifty inches of rain during the season, fever does not appear until late, viz. July ; but should, on the contrary, the wet season be short, as in 1887-8, when we had only about eighteen inches during the whole wet season, then the fever season begins early, as it did tliis year, in April. The reason why the autumn and winter months are pre-eminently those of malarial fever is accounted for thus : After the rainy season is over, the lagoons and low-lying lands become dry from the heat of the sun, and consequent evajioration ; and the jirevailing S.E. winds, blowing over this low-lying country, bring malaria in their course. Locality. Malarial fevers appear to confine themselves to the low-lying grounds, dense scrubs where the soil is rich and luxuriant, or to those parts where the earth is freshly disturbed. Fever is not heard of on the table-lands or at any considerable elevation, except in imported cases. Types, (a) Intermiiteul ((quotidian, tertian, and quartan) ; (li) Remittent ; (c) Tijpho-vialariaL MALARIAL FEVERS IN TROPICAL QUEENSLAXD. 65 The internuttent varieties of quotidian, and especially tertian, are the most prevalent in the Gulf district. Remittent is rare, as I have only seen two cases of it during my four years' residence. The typho- malarial, observed by Dr. White at Geraldton, is decidedly a malignant form of malarial fever, and is decidedly fatal. The system of the patient appears charged with the malarial poison, and in several cases the illness appeared to come on suddenly, and in others there was a history of neglected intermittent or remittent fever for some time previously. In most cases it has a tendency to run rapidly to a fatal termination, unless checked by proper remedies. Dr. "White also says that in the early days of settlement on the Johnstone River, when malarial fever may be said to liave been at its worst, had cases became as '■'■yellow as a guinea," and that lie has had three such cases (one European and two Kanakas) which resulted fatally. In each of these, jaundice supervened before death, but it is not the rule, as he did not obserA^e it in others of his cases, whether fatal or not. Severity. The cases I have seen of intermittent fever are usually of a mild type, especially if they are treated early and occur in an otherwise healthy subject. One of the first cases admitted into the Burke District Hospital was also one of the severest attacks I have seen, as the patient was insensible and delirious for a week after admission ; but this was quite accounted for, as it was ascertained that he liad been drinking heavily for some days before. The most severe cases, and usually the most prolonged, occur in those who have been living on poor diet for a con- siderable time, and who have had no treatment. Of remittent fever I liave only seen two cases, and these were both fatal ; one of them had been subject to attacks of malarial fever whilst resident in the Southern States of America. The typho-malarial, as mentioned above, is a decidedly fatal form of fever. Duration. The duration of intermittent fever, when treated, is usually short in first attacks and in healthy subjects, but in ansemic subjects usually two or three weeks. But, as a rule, it is very liable to recur sooner or later, if the person continues to live in the district where he contracted it, and generally at the same season the following year, if not sooner. The duration of remittent is from five to tvventy days, or longer, and the convalescence from it is often very prolonged, if the patient remains in the same district where contracted. The duration of typho-malarial is from two to three weeks, but death may occur as early as the second day : when convalescence is established, it is usually rapid and comj)lete. When recovery does take place from an attack of typho-malarial fever, it appears to render the patient proof against malarial influences for some time to come. Amenability to Drugs. All these fevers, with the exception of the remittent type, are very amenable to quinine, arsenic, eucalyptus, salicylic acid, or salicylate of soda. Eucalyptus I used frequently at first, but found it so nauseous, F 66 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. that I have not used it lately. Quinine, in a mixture or in a pill, I most usually rely vipon, and find it most efficacious ; hy])odevmically, I have not used it, as I have not lieen able to get a soluble form of it, but I hear of its being most satisfactor}^ so I may employ it later. Quinine and salicylate of soda, together, prove also efficacious. I frequently use at the commencement of an attack either an emetic, or a purgative of calomel and compound jalap powder to unload the liver, and I find it also satisfactor}'. In the convalescent stage, I usually give some pre- pai'ation of iron. I intend also trying the picrate of ammonium as recommended by Dr. H, M. Clai'k, of Amritsar, India, in the Lancet of February 19, 1887, but the drug has been difficult to procure in the Colonies. Sequelae. The spleen and liver are almost always enlarged to some extent during an attack, but become normal later on. Repeated attacks leave the spleen chronically enlarged, but to nothing like the size seen either in India or in the Eastern Counties in England. Dr. White had recently under his care some ill-fed children, who had had repeated attacks of intermittent fever without any treatment, whose spleens were in each case the real " ague-cake" and in each case, when first seen, the spleen extended almost to the pubes. IMalarial cachexia is frequently met with as a sequela to both intermittent and remittent fevers ; it some- times, however, comes on without fever developing itself. Removal of the person from the district effects, generally, a speedy cure. In conclusion, I find that prolonged residence in a malarious district does not render one insusceptible to attacks of fever, for I had a patient recently who had been resident thirteen years in the Gulf, and was at that time suffering from a first attack of malarial fever. I have also several cases of residents of some years' standing suffering from a first attack. The residents in the town are not so liable to attacks as those living outside in the bush, or travellers. And this is accounted for because of their better and more varied diet, and the superior quality of their drinking water. The bushman and the traveller have frequently to drink whatever water they can get, and this is frequently stagnant, and from lagoons tilled with decaying and dead animal and vegetable matter. Likewise, they sleep chiefly on the ground, and invariably in the proximity of some water-hole, and exposed to the full force of the malaria-carrying winds. Dr. White, of Gei-aldton, who resided and practised in a malarious district in India previoiis to coming to Queensland, states that the fevers found in India are undoubtedly the same as those met with here in tropical Queensland. THE HEPATIC ELEMENT IX DISEASE. 67 THE HEPATIC ELEMENT IN DISEASE. By J. W. SppaxGTiiORPE, M.A., :\1.D. Melb., ZM.R.C.P. Lond. Phj'sician to the ilelbourne Hospital. Lectviver to the University on Therai^eutics, Dietetics and Hygiene. Tlie for<=!going title is epigram inatic, rather than logically accurate. It is the nitrogen-compounding, and bile-producing functions which are under review, and not the glycogen-forraing or poison-sepai-ating, otherwise than as they suffer synipathetically. Structural diseases and degenerations are similarly outside present discussion. Thus restricted, liowever, in scope, the hepatic element merits profound study. The present paper raises the questions of the Made range of its operations, some of the more impoitant of its ill-understood associations, and its predominance amongst the factors of disease throughout the colony. (1) Its WIDE PvANGE OF OPERATION. The local hepatic action concerned is (a) the dehydration of jjejDtones into insolul)le albumen, to be gradually served out to the blood stream in compounds of complex fornuilai and feeble chemical affinities ; and (6) the sejjaration of the bile for circulation, in the portal system for purposes of fat digestion, fjecal disinfection, and extrusion. The fjeneral hepatic action concerned is the resultant throughout the system of the circulation of these explosive nitrogenous compounds. As only a small portion enters into cell repair as fixed-albumen, or ]:)roceeds to form fac, the function of the larger portion must be sought elsewhere. The view is here taken, that in certain, at })resent ill-understood, but still, in all probability, perfectly definite amounts and combinations, these compounds are so essentially bound up with the local production of force of all kinds, that they may be called the physiolor/ical stimuli necessary for the functional activity of the tissue and organ. When they are present in normal proportions, the course of organic life Avill run smoothlj', and the appro]:)riate effects will follow other stimuli, ]:)eripheral and central. The key to the interi)retation of the part played by the hepatic element in disease, lies in the recognition of a corollary from this law, viz., that in disease, not only is the local action ill-performed, but this state of physiological stimulation passes into a stage of pathological irritation, by which functional disturbances may be produced in all parts, but especially in the part vulnerable in the individual case. Observation verifies the truth of this conclusion ; yet, neither the text- books nor the practitioner are found, as a rule, attaching thereto its vast clinical value. Hence, treatment is often found to be symptomatic, from the non-i-ecognition of the basis, u])on which depends this system — wide series of functional disturbances. The following table, therefore, may be of use, since it contains a more complete list of the symptomatology F 2 68 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. than Las been found elsewhere, and since it is based upon clinical expei'ience, and not upon a priori pi'obabilities : — ■ Site of Disturbance. lu the liver itself. lu the tissues. lu circulatory system. lu respiratory system. In miiscular system. lu mucous membranes. In serous mem- branes; iu syno- vial membranes. In nervous system. Symptoms Produced. (a) Periodic hepatic stasis and congestion. {b) Periodic portal stasis. (c) Irregular bile separation. Pigmentary deposits, dating even from fcetal hfe, and continuous after Ijirth. Tendency to local inflam- mations, and interruiDted healing of injured parts. High tension of arteries, accentuated second sound, slow pulse, possible cardiac hypertrophy. Arterio-capillary fibrosis, endo- arteritis, rupture of vessels, even endocarditis. Wheezing, asthmatic attacks. Bronchial si^asm present in ordinary catarrhal con- ditions. Musciilar cramps, " mus- cular rheumatism," bron- chial spasm, cardiac hyper- trophy. " Rheumatic sore-throat " and catarrhs. Tendency to inflammation, pleurisy, synovitis, peri- carditis, periostitis. Explosibility and want of control, headaches, vertigo, restlessness, migraine, dis- turbed sleep, irritable tem- per, fidgets, haUucina- tions, fits of passion, strange modes of thought, semi -insane acts, various neuralgia;, even epilepsy and mania in the markedly neurotic, climacteric neu- roses, well marked. Remarks. Hence the feeling of weight and scapular pain. Hence the tendency to piles, varicocele, ovarian and uterine congestion, dys- menorrhcea, menorrhagia, etc. Hence the irregular bowels, variable stools, flatus, colic, coated tongue, mal-assimi- lation of fat, the nasty taste in the mouth, and the jaundice of varied extent. Hence the dark skin, hair, and complexion , which almost invariably charac- terise the hepatic ; hence, also, the black specks, &c. before the eyes. The first three almost in- variably }5resent. Generally more marked when combined with renal de- fects. Earely absent, if sought for. The former very character istic. Herein we have the possi- bilities of the joint affec- tions, &c., of acute rheu- matism. The endurance and deter- mination characteristic of the class may be ascribed to the continued brain stimulation. The combination of the hepatic and ncrvons seems a colonial feature. THE HEPATIC ELEMENT IN DISEASE. 69 Site of Disturbaxce. Symptoms Prodlxed. Remarks. In skin. In kidney. Outbreaks of papular cha- racter — fiu'unculi, lichen, urticaria, and also psoriasis. Azoturia, with renal, vesical, and urethral irritation, grit, gravel, calculi ; finally granular kidney, where de- fective elimination is added to mal-assimilation. Eczema seems to occur rather in the cases of renal inadec^uacy. Also an extremely common combination. In the foregoing, no attempt has been made lo se])arate the remote effects of biliary disturbances from those of disturbance of the nitrogen compounding function, because the two are so intimately related that differentiation is practically impossible. Probably, however, pigmentary discolorations connote graver disturbance of the bile function, whilst the remote effects of the latter upon the brain, as seen in hypochondriasis and jaundice, i)oint to depression rather than to irritation, as is the case with the former. Again, in those whose vulnerability is thus hepatic, obesity may follow from greater efficiency of the glycogenic function, or diabetes supervene upon its disturbance. Lastly, the temperament is generally inherited, and marked by the above remote symptoms, in addition to the generally recognised visual characteristics. But the symptoms may be produced even in these without any such predisposition, by continued excess in meat, malt liquors, or heavy wines. (2) Some of the more important of the less recognised ASSOCIATIONS OF THE HePATIC ElEMENT. (a) Rheumatism in all its varieties, is hei-e placed by the writer : — (a) Muscular rheumatlsni may be at once dismissed as admittedly hepatic in origin. (6) Charcot and others have remarked how frequently chroiuc articular rheumatism in all its forms, is associated with migraine, asthmatic attacks, muscular pains, skin eruptions, and othei' forms of hepatic disturbance. The present paper adduces no further evidence in sup})ort of this connection. Charcot, however, and others have clearly shown that all varieties are causally connected with the acute articular form — hence, this theory of the hepatic origin of rheumatism stands or falls according as the hepatic element can be proven or not to be causally connected with the acute variety. (e) The evidence advanced in favour of this connection between the hepatic element and acute rlwumatism, is as follows : — (1) The connection already mentioned between chronic rheumatism and the hepatic temperament. (2) The recognised origination of an attack in hepatic derangement. Thus, in " Quain's Dictionary," Dr. Mitchell Bruce remarks how " an attack of acute rheumatism is occasionally referred to derangements of digestion, and of the functions of the liver, especially in subjects who 70 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. have previously suffered." Closer observation will show this to be the rule rather than the exception, exposure to wet and cold often preceding this derangement, and causing it. (3) The fact that " indulgence in abundant, rich, or indigestible food ■will certainly determine a relapse in persons convalescing from the disease." — (Mitchell Bruce, loc. cit.) (4) The fact that the preventative treatment generally advocated is essentially that of hepatic vulnerability and the hepatic temperament, viz.. diet simple, and largely vegetarian, free action of skin, bowels and kidney, prevention of hepatic congestion by flannel underclothing, avoidance of malt liquors and sweet wines, and preparation for damp and sudden atmospheric changes. (5) Direct observation as to the class of cases in whom acute rheumatism has occurred. During the past 12 months, 62 cases have come under the writer's observation in the wards of the hospital and outside, either suffering from an existent attack of acute rheumatism, or with a history of a previous attack. In 12, unfortunately, no note w^as made as to temperament, but out of the remaining 50, no less than 44 are noted as having been mai'kedly hepatic ; whilst in 3 of sanguine temperament, there was a history of beer-drinking, and of the other 3 cases — of gonorrheal rheumatism — one, at least, was unmistakably hepatic. This shows, in the writer's opinion, that there is an hepatic element in the causation of acute rheumatism, and from the analogy of other effects of the same cause, thei'e seems nothing in the pathology or symptoms of the disease to upset the hypothesis that the local irritant at Avork is hepatic in origin. What may be the nature of the nitrogenous compound, remains unsettled. That the joints are affected may depiend, as Jonathan Hutchinson remarks, upon an ai'thritic \'ulnerability, just as occurs in other parts in the same disease. The co-existence of endocarditis is readily explained, but the characteristic sweating and rise in temperature remain problems which are difficult of satisfactory solution upon this, as upon all other hypotheses. {d) As to gout and rlieuwatic gout, it is held by the writer, that gout is a matter between the liver and the kidney, but more a disease of defective elimination than of mal-assimilation. The theory of the hepatic origin of rheumatism affords an explanation of rheumatic gout as a distinct disease, in which both hep;vtic deiangement and renal incomj)etence are present, but the former dominating the latter. Thus, the general conclusion arrived at is, that all the varieties of disease styled " rheumatism" and " rheumatic," are members of the one family, and that, as a rule, which has been found invariable, the rheumatic are also hepatic. (b) The effects of the hepatic element in the nervous system are deeper and wider than is usually recognised, and merit a higher place in clinical medicine than is usually given them. This is especially the case in this colony, wherein it is claimed the main tendency is towards the bilio- nervous tem])erament. Thus, in ei)ilepsy, out of 61 consecutive cases, the writer found no less than 19 markedly hepatic, and hepatic treatment proved effectual, even after the .skilful and continued use of specific sedatives had ))roved a failure. In colonial diabetes also, the liepatic clement almost always exists, in conjunction with the neurotic. The same element is the basis of the varied and numerous ailments NOTES OF SEVEN CASES OF TYPHLITIS. 71 which are enumerated in the foregoing table, inider the heading of Ne7'i'oiis iSi/D/pfrims. It is found giving a special character to the manifestations of influenza, and it is claimed as a prominent factor in the })roduction of our exceptional lunacy statistics. (3) The Predomixaxce of this Element in the Production of Colonial Disease. In the opinion of the writer, the hepatic element occupies, in the production of Victorian disease, a position second to no other cause, excepting, perhaps, insanitary arrangements and surroundings. Any gathering of the general public will suffice to show the numerical preponderance of the hepatic over all other temperaments, and the records of hospital and private case books will be found to demonstrate the same result, even in cases where the general derangement has led the individual to seek for relief from his troubles. The writer believes that the wide operation of the same cause may be further seen in the extent to which rheumatism, renal, and neurotic diseases prevail. The cause of this predominance of the hepatic factor amongst us seems threefold : — (a) The extreme variability of otir climate. (6) The amoitnt and nature of our alcoholic stimulants. (c) Our excessive use of meat as an article of diet. Each of these points is fully discussed in a paper before this Congress, on the "Hygienic Conditions Existent in Victoria." Further notice here is, therefore, unnecessarv. NOTES OF SEVEN CASES OF TYPHLITIS. By A. S. Joske, M.B., Ch. B. Late Eesident Medical Officer, Alfred Hospital, Melbourne. The following brief notes are of cases of typhlitis that have occurred in the Alfred Hospital in 1886, 1887, and 18»8, and of one case I have seen in my own practice. The occurrence of so many after typhoid fever has led me to believe that a number of so-called relapses are, in reality, due to the formation of abscesses in the neighbourhood of the ileo-ceecal valve. If my sur- mise be correct, it helps to show that such a sequela is not altogether unfavourable. (1) M. C, ait. 31, female, was admitted into the Alfred Hospital in September 1887. Twelve days previous to admission, while lifting, felt a sudden pain in the light iliac region, which became persistent. On admission, had some dulness on percussion in the right iliac region, with drav^'ing up of right thigh. Her temperature was 103^ Had local applications applied to seat of dulness. Had rigors on September 23. The swelling was aspirated on the 27th September, and pus drawn off. This aspirating was done three times. Tongue became red and raw. Temperature continued persistent. Bogginess then felt posteriorly. 72 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Free incision was made in right lumbar region, and a quantity of pus evacuated, and a tube was inserted. Temperature fell rapidly. The pus soon stopped, and the patient was discharged, cured, on 11th November. (2) "VV. M., cet. 28, male, was admitted into the Alfred Hospital in April 1887. Had mild typhoid fever, the temperature falling to normal on the twenty-fifth day. He had pain in the right iliac region, with rigors. Dulness in the right iliac region, on percussion. Temperature ran up to 104'4° gradually, with exacerbations and remissions. On the thirty-seventh day, passed about four ounces of pus. Pain disappeared, and dulness diminished. Was quite well on the fifty-second day. (3) A. F., ret. 29, male, was admitted into the Alfred Hospital in April 1887. Had mild typhoid fever ; temperature fell to normal on the sixteenth day ; then had pain in the right lumbar and iliac region. A swelling gradually formed. Had rigors. Temperature rose to 104'6°. On twenty-fifth day, passed a quantity of pus. The temperature fell to normal on the thirtieth day, after passing a little more pus twice. (■4) A. H., fet. 23, male, was admitted into the Alfred Hospital in March 1887. Had bad typhoid fever, with pneumonia and haemorrhage. Had rigors on the forty-second day. Had no particular dulness in the right iliac region, but pain between that and the umbilicus. Passed pus on several occasions up to the fifty-seventh day. Temperature fell to normal on the seventy -seventh day. (5) C. M., jet. 29, male, was admitted into the Alfred Hospital in September 1887. Had bad typhoid, with some haemorrhage. Like Case 4, had no particular dulness, but pain between the umbilical and right iliac region. His temperature became normal on the thirty-eighth day ; then he had shiverings, and passed pus on four occasions. This patient, in addition to the pain, complained of peculiar rumblings in the umbilical region until the pus came away. (6) A. C, fet. 26, male, was admitted into the Alfred Hospital in December 1886. He had a mild typhoid fever, the temperature becoming normal on the 28th day. Then a hardening and thickening, with dulness and pain on percussion, could be felt in tlie ileo-csecal region. The temperature rose until the thirty-fourth day of illness, when he passed two ounces of pus, when the temperatui-e fell to normal, and the swelling gradually disappeared. (7) E. S., ret. 15, female, had a mild form of typhoid fever in April 1888. Twenty-six days after first being laid up, had pain in the right iliac region, with some dulness and pain on percussion. Had rigors, with rise of temperature. She passed pus six days afterwards ; then the temperature fell, and the swelling disappeared. She again had an attack in August 1888, with pain in the right iliac region and dulness, but recovered on passing pus on the eighth day of illness. She had two other attacks, in September and October, but since then has enjoyed excellent health. CONSTITUTIONAL FACTOR IN RELATION TO DISEASE. 73 THE IMPORTANCE OF THE CONSTITUTIONAL FACTOR IN RELATION TO DISEASE. By James Robertson, M.A., M.D. Formerly Physiciau to the Melbourne Hospital, and Lecturer ou Medicine in the TJniversity of Melbonrue. Amidst the daily routine of professional life, and the cares and anxieties incident to the active practice of our jirofession, it is difficult to find time for study. Too frequently, after the duties of the day are ended, the body is exhausted by fatigue, and the mind is unequal to ovei'come the vim inertice with which it is oppressed. Another difficulty, and no small one, that met me at the inception of my design to contribute a paper to this Intercolonial Congress, was the choice of a subject. This was surmounted by our very active and energetic Secretary allotting one to me. Under the circumstances, I hope my subject and its treatment may meet with the favour of a sympathetic audience. The subject thus assigned to me, "The Importance of the Constitutional Factor in Relation to Disease," is very comprehensive, and admits of voluminous treatment; but it will be my aim to make my remarks brief and practical, as far as possible. It will be readily allowed, that a careful examination of the general symptoms and physical signs is all-important in determining the nature and locality of a disease; but to enable us to complete the diagnosis, and to indicate the prognosis and treatment, it is not less important to ascertain the " constitutional factor." It may be truly said, that the "constitutional factor" is the key-note to treatment. It is therefore necessary, in every case, to note particularly the appearance and physique of the patient, to obtain a knowledge of his previous state of health and tendency to disease, and, as far as possible, of his family history. " Like produces like," is the general law of life. It is manifested alike in the vegetable and animal kingdoms. The embryo plant unfolds its leaves, and expands its branches, after the manner of the parent tree. The child grows up in general likeness and bodily conformation, the type of one or other parent. Even vices of formation, physical deformities, are not infrequently inherited. The child also inherits the temperaments of the parents, often so blended, that it is difficult to decide which temperament predominates most, that of the father, or that of the mother. The characteristics manifested by the ])hysiognomic appearance and general conformation, the development and activity of the various organs, enable us to recognise the temperament best marked or typified. Although each temperament is said to predispose to certain diseases, yet the most robust health may be enjoyed Ijy individuals of the sanguine, or of the bilious temperament, and even by those of the lymphatic, or of the nervous temperament, when their subjects are placed under conditions favourable to health. Children inherit not only the temperament, but the diathesis, of their parents — that morbid tendency or predisposition to disease, liable to be transmitted from parents to children. When both parents manifest the 74 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. same diathesis, it may become strongly expressed in the children, by external bodily features and conformation, as in the strumous (Jiathesis. Again, a diathesis may be feebly or faintly marked, yet it is innate, born with the individual, and liable to become developed under the influence of exciting causes. It cannot be said that diseases are, as a rule, actually inherited. Only such peculiarities of constitution as predispose to them, and that favour their development, are so. Children are not born with tuberculosis, rheumatism, or gout, but with such latent conditions of constitution, as lead to their development in after years, when influenced by the operation of agents acting from without — exopathic; or, it may be, generated within — endopathic. The morbid hereditary tendency may be so strong, that disease may become developed under circumstances favourable to health, and even when care is taken to prevent it. Tuberculosis may be adduced as an instance in point. Again, when the predisposition exists, the disease may remain latent until a certain age, and then become actively developed, as occurs in phthisis, gout, cancer, itc. Morbid tendencies are liable to be brought into activity at different epochs. Syphilis and scrofula are manifested in early life ; phthisis and rheumatism, at or about tlie age of puberty and adult age; gout, beyond the middle period of life; asthma and cancer, in advanced years. Some diseases are not marked by any external features, or other indications in early life, but are none the less to be considered hereditary. I may particularly instance diseases of nervous origin — chorea, mania, epilepsy, apoplexy, paralysis, neuralgia; also diabetes, cancer, and some skin diseases. All the children of the same parents do not partake alike of their morbid tendencies. When the parents exhibit diff'eient diatheses, some of the children may inherit and manifest that of the father, and some that of the mother, in a more pronounced form. It is generally allowed that the morl)id tendency of the mother is more liable to be transmitted than that of the father. Another peculiarity of constitutional disease is the law of atavism. The hereditary tendency may fail to be expressed in the children of parents known to be the subjects of disease, and become developed in the grandchildren. The tendency lies dormant, as it were, in one generation, and becomes expressed in the next. I have said that children are born with a tendency or proclivity to disease, but in some cases they are born the subjects of actually existing disease. The cachexia is transmitted, the disease is congenital — born with the individual. This fact is well illustrated in congenital syphilis. Cases are reported of small-pox and measles, and also of intermittent fever, being congenital, due to the specific poisons of those diseases operating through the systems of the mothers. In constitutional syphilis, a peculiarity is sometimes observable in the transmission of the disease. One child may be born apparently perfectly healthy, and free from the syphilitic taint, while the next j)resents undoubted signs of the disease. The sy])hilitic taint is mani- fested in a variety of ways, both externally and internally. The I CONSTITUTIOXAL FACTOR IX RELATION TO DISEASE. 75 external appearances are readily recognisable in affections of the nasal bones, and of the skin and umcous membranes, and, at a later stage, by the appearance of the teeth. Tiie morbid changes induced in internal organs are often very insidious and very serious, affecting, as thev do, the brain, liver, lungs, &c., while the diagnosis is very o))scure, and can only be determined by a process of exclusion, and a knowledge of the " constitutional factor." This knowledge is still more imi)ortant in enabling us to form a prognosis and indicate the treatment, inasmuch as the treatment, to ))e successful, must be directed to the specific constitutional disease. To illustrate the importance of recognising the " constitutional factor," I shall refer a little more in detail to the scrofulous or tubercular cache,rut. I presume it will be allowed that scrofulosis and tuberculosis may now be regarded as commensurate or convertible terms, seeing that the bacillus tuberculosis finds a habitat alike in scrofulous glands and tubercular lungs, and is said to be the cause of both conditions. Scrofula may be regarded as the manifestation of tuberculosis in childhood, and phthisis in adult age. In childhood, the bacillus tuberculosis appears to have some special afiinity for the lymphatic glands of the neck, the mesenteric and bronchial glands, and for serous and mucous membranes, bones, and joints ; while in adult life it selects the lung.s, and other internal organs, as ijoints of attack, as being, it is assumed, partes minoris resistentice. The reason why, is problematical. We know, however, that healthy vigorous children, with abundance of nutritious food, living under favourable hygienic conditions, are able to resist tuberculosis ; and that the weakly, badly fed, and neglected, are liable to fall A"ictims to it. This is especially the case when the hereditary predisposition is strongly expressed, for then the onset of the disease occurs at an early age, and its progress is more rapid. In this Colony, the conditions favourable to the development of tuberculosis do not prevail extensively ; and consequently, we find that tabes mesenterica, tubercular peritonitis, and meningitis, are comparatively rare, the mortality from those diseases not amounting to one-half that incident to England and Wales. Children who have inherited the tubercular diathesis may, iinder healthy conditions, pass safely through the trials of childhood, and reach the age of puberty. Tuberculosis of the lungs is then liable to super- vene, under the influence of some exciting cause — it may be, exposure to cold. Catarrhal bronchitis, or other inflammatory affections of the lungs, such as sub-acute pneumonia or pleurisy, not infrequently merge in pht/iisis piiJmnnum. The occurrence of any of the exanthemata, or acute specific fevers, may so debilitate the system as to render it prone to tubercular disease. Of course, the advent of phthisis under such circumstances presupposes exposure to the influence of the bacillus tuberculosis, and its introduction into the system. When, however, care has been taken to promote recovery from debilitating diseases, to restore the strength by suitable nourishment, to correct errors of diges- tion, and thus promote healthy nutrition, immunity may be obtained fronr the invasion of bacilli. The important factor, therefore, in incij)ient phthisis, is the constitu- tional ; for, without doubt, bacilli are often inhaled by many who come into 76 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. contact with phthisical subjects, and yet the disease is not communicated. We have also abundant evidence to ])rove that tuberculosis is often arrested in childhood, youth, and adult age. This is shown by the subsidence of well-inarked symptoms, and physical signs, by restoration to Iiealth, by improved nutrition, and increased weight. Further evidence of the curability of the disease is furnished by the presence of calcareous or chalky bodies in glands, lungs, and other internal organs, and by the cicatrices and small cavities in the apices of the lungs, so frequently found after death. In such cases, we are constrained to believe that bacilli die, or become inert, or that their inroads have been arrested by healthy living tissues, and they have been cast ofi'. The importance of studying " the constitutional factor," in indicating the treatment of disease, cannot, perhaps, be more strongly enforced, than by passing in review the treatment suggested by the bacilJary theory of tuberculosis, and that directed to support and strengthen the system, by such means as promote liealthy nutrition. The latter I cannot but I'egard as the more rational, and, so far as yet demonstrated, the most successful mode of practice. The dominant idea, influencing the treatment of tuberculosis at the present day, is the discovery of some agent calculated to destroy the life of the bacilli, without injury to the system, and certainly the measures adopted in accordance vv'ith this view cannot as yet be pronounced a success. oSTumerous antiseptic and anti-j)arasitic remedies have been introduced into practice. Their effects have been tested by their action on bacilli and other micro-organisms, external to the bod}', in order to determine the quantity, or strength, of the various parasiticides necessary to arrest their development; but their action on bacilli, in the tissues of the living body, cannot be thus estimated, for very obvious reasons. The mode of administration generally adopted has been by inhalation, subcutaneous injection, intra-pulmonary injection, and injection ^jer rectum. A mere enumeration of medicaments employed, will show the bias given to therapeutical reseai-ch by the adoption of a theory. Mercury perchloride and bin-iodide, iodine and its compounds, iodoform, carbolic acid, creosote, lerebene, turpentine, eucalyptol, aniline, cai-bon-bisulphide, et hoc genus omne, have been employed. Ingenious instruments have been devised for inhalation, and for injection of gases 2^^^' Tectum, but their use lias not been attended with any positive or permanent good result. Bacilli are found to survive all efforts to destroy them, and the means used are not always innocuous to the patients. The most successful treatment yet discovered for the prevention and cure of tuberculosis, is that directed to promote the general health. When the tendency or proclivity to the disease is inherited, our hope and strength rest in adopting measures of prevention. These consist in removing a patient from all unhealthy surroundings, from all debilitating causes, and in enforcing the observance of general hygienic measures — early hours, bathing, cold or tepid sponging, and friction, regular habits, exercise in the open air, change of air and scene. Special attention should be given to the state of the digestive organs, as often a peculiar form of dyspepsia ])recedes the morbid changes. Errors of digestion should be corrected by the use of such medicines as are indicated, and of I COXSTITUTIOXAL FACTOR IX UELATIOX TO DISKASE. 77 wholesome, nutritious, and easily-digested food. 80 long as the nutritive processes are active and healthy, there is little occasion to dread the inroads of bacilli. The means that prove most efficacious in the treatment of tubercular disease, are just tho.se that give tone to the s3-stem, and promote healthy nutrition. The advantage of residence at a high altitude is, in a measure, due to the diminished jn-essure and purity of the atmosphere, but still more to the bracing effect of the cold, which invigorates the system, stimulating the various functions, and esi)ecially the appetite, digestion, and assimilation. Alpine air is not to be regarded as a specific, but rather as a tonic plan of treatment, most beneficial in the early stages of the disease, when lesions are not extensive, and in chronic cases uncompli- cated with disease of the kidneys or circulatory system. A mild, warm climate has been recommended, and without doubt has served to prolong life in cases of advanced disease. Its effect, however, is not conducive to recovery, as it induces languor, lassitude, and prostration of strength. By its enervating influence, it unfits for exercise, tends to destroy the appetite, and impair digestion, and thus leads to mal-nutrition, and pi'ogressive emaciation. Sea voyages are beneficial, provided the cuisine is good, and table liberal, the constant renewal of pure air favouring or inducing healthy functional activity. In the Australian Colonies, a climate suitable for consumptive patients may be found at all seasons of the year, but only by migrating from south to north, and again from north to south, according to the season. In calculating the benefit to be derived from change of climate, not only is the stage and extent of the disease to be considered, but the means of the patient to procure suitable residence, food, and even luxuries and amusements. If he has to earn his living by engaging in some in-door employment, if he has to sacrifice his comfort to " the necessity of living," change of climate will avail but little. I shall now briefly direct attention to another constitutional disease met with in middle age or advanced yeai's — gout, or lithiasis, a term applied to it from the condition on which it depends. It is to gout occurring in its chronic and irregular forms that my remarks are particularly directed. The gouty diathesis is often inherited, but the cachexia may be acquired, may become developed, even in those of temperate habits as regards drink, when animal food is consumed in excess of the wants of the system, and indolent habits are indulged, or insufficient exercise is taken. The disease has always been attributed to indulgence in the pleasures of the table, to wine and good living, but it may arise at a certain age in those predisposed by heredity, induced by some temporarily exciting cause. It is liable to assume many forms or phases, to imitate or complicate many diseases. It is veritably a protean malady. Although its most characteric manifestations are observed in nodosities of the smaller joints, and effusions into the synovial membranes of the larger joints, it is liable to implicate every organ and tissue of the body. It affects the nervous, circulatory, respiratory, alimentary, and emunctory organs. It is to be recognised in cerebral affections, in severe headaches, vertigo, partial paresis, temporary troubles of special senses, affections of the eye and ear, neuralgia of different nerves, more especially of the sciatic. Its effects on the iieart are indicated by palpitation, and irregularity of its action, 78 INTERCOLONIAL MEDICAL CONnRESS OP AUSTRALASIA. by flying pains, and a feeling of oppression in the cardiac region ; and on the blood-vessels, by atheroma of the arteries ; on the respiratory organs, by inducing or modifying chronic bronchitis and asthma ; on the stomach and liver, bj' dyspeptic troubles — pain, acidity, flatulency, and deranged bowels ; and on the kidneys and urinaiy^ tract, by degenerative changes of the kidneys, and urinary irritation from elimination of lithates. It is not infrequently remarked, when a patient is suffering from various anomalous symj)toms suggestive of what may be termed latent gout, that a regular iic of gout would prove curative, as, usually, improved health follows. It is like the bursting of a thunder-storm, which purifies the atmosphere. Although gout and rheumatism are characterised by very different and well-defined symptoms in the acute form, there is a very close relationship between them when occurring in the chronic form. Both are due to morbid poisons generated in the system and circulating in the blood, which affect different tissues and organs, lithic acid being accepted as the morbid factor in the one, and lactic acid in the other. Both are manifested by derangement of the functions of assimilation, and of secretion and excretion, and both yield to the same line of treatment — alkaline, alterative, and eliminatory. The importance of studying " the constitutional factor" is well exemplified in all diseases associated with the gouty diathesis. In inflammatory affections occurring after middle age, the possibility of their being so associated, and thereby modified, demands inquiry. Not infrequently it is found that diseases affecting the synovial and mucous membranes are intractable to treatment ; that effusions into joints, tonsillitis, laryngitis, bronchitis, asthma, and cystitis, do not readily respond to treatment, unless it be directed to counteract the prevailing diathesis. Rarely have we to treat simple inflammation ; but rather some compound or complex disease, the lesult, it may be, of various morljid factoi's mixed or blended together. We are, therefore, greatly assisted in our treatment of the many anomalous and obscure affections met with in advanced years, by bearing in mind their not infrequent complication with the gouty cachexia. In obstinate dj^spepsia, with hepatic derangement and urinary irritation, " the constitutional factor" is often plainly disclosed by the so-called "Old Father Christmas" ftice of the patient. In cases of dyspnoea, with feeble intermittent action of the heart, palpitation, and flying pains about the chest, the gouty cachexia may be revealed by nodosities, or tophi of the smaller joints ; or perhajis, m the helix of the ear. When no such evidence is ajjparent, and yet signs are })resent of impeded circulation, congestion of the liver and kidneys, with functional disturbances, or irregularity of the heart's action, we aie justified in referring them to the constitutional factor, in the absence of e\idence of valvular disease. We may thus be enabled to give a more favom-able prognosis, especially if we find, on enquiry, a history of family predisposition, or heredity. The connect diagnosis of a disease iss aid to be half its treatment ; at all events, it is the most important element in regard to its successful treatment. In treating diseases complicated with gout, medicines require to be given in jiidicious combination. The treatment to be adopted is PHTHISIS IN NEW ZEALAND. 79 suggested by " the constitutional factor," and ])y other indications jiresent. If our object be to promote the elimination of effete and excrementitious matter, that may be most readily acconiplishr'd by the administration of natural saline alkaline aperient and diuretic waters, with colchicum, in sthenic cases. The combination of iodide of potassium, with ammonia, colchicum, and senega, is highly efficient in some cases of chronic bronchitis, with a tendency to asthma. In asthenic cases, characterised by feeble action of the heart, passive congestion of internal organs, and general debility, treatment of an active or depressing kind is contra-indicated, and such tonics as iron, quinine, and strychnine may be demanded, especially when the heart is very feeble, and perhaps dilated. Even under sucli circumstances, tonics are not always attended with benefit. It may be necessary to jirecede their employment by such medicines as promote the action of the liver, bowels, kidneys, or skin ; or to combine a tonic and eliminating plan of treatment. A very useful combination, in asthenic cardiac cases, consists of iron and arsenic, or a compound of iron with a vegetable acid and digitalis. The strength is to be maintained by tonics, stimulants, and nutritious easily-digestible articles of food, secretion and exci-etion being at the same time promoted, in order to eliminate effete products from the system. PHTHISIS IN NEW ZEALAND. By D. CoLQUiioUxN, M.D. Lond., M.R.C.P. Lond. Lecturer on the Practice of Medicine, Otago University. A few months ago, a medical friend in England wrote to me about a patient of his suffering from consum])tion, whom he had advised to go to New Zealand. His patient had subsequently consulted a specialist in London, who fell foul of the recommendation, and said that New Zealand was the worst place he could go to. In a notice in the Lancet, in July 1887, on a book by Dr. Lindsay on the Climatic Treatment of Consumption, the reviewer remarks that " Dr. Lindsay wisely points out the undesirability of this remarkable country (New Zealand) for the invalid, however attractive for the tourist." It would not be difficult to find among medical men in Australia and New Zealand many hold- ing similar opinions, and I propose, in this paper, to discuss the subject, rather from a statistical than from an impressional standpoint. It will be convenient to liegin with the latest official statistics on the subject, and I will first give the official returns for 1887, showing the population in the various provincial districts of New Zealand, and the number of deaths from ])hthisis in each. A glance at a map of New Zealand will show the situation of the various districts, and I will discuss further on the occupations and social conditions of the inhabitants. 80 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Table I. Statistics of Phthisis for 1887. Population. Deaths from Phthisis. Per 10,000 Living. Males. Females. Total. Aucldand 134,1*^8 81 43 124 9-3 Taranaki 18,737 10 5 15 8-0 Hawke's Baj- 25,509 15 8 23 9-0 Welliugtou 80,328 34 33 67 8-3 Marlborough 11,547 3 2 5 4-4 Nelson . . 30,979 10 5 15 4-8 Westland 16,242 14 6 20 12-3 Canterbury 125,2 GS 62 53 115 9-1 Otago . . 153,388 86 64 150 9-7 Chatham Islands 210 — — — — The total estimated population of tlie Colony (exclusive of Maoris) was 590,374 ; the total number of deaths from phthisis was 534, or 8 '9 5 per 10,000 inhabitants, and 8*7 per cent, of deaths fi'om all causes. As these are the statistics for one year only, they are evidently not to be taken as showing the general incidence of deaths from consumption in New Zealand, but they will be useful to compare with results taken from a series of years. I am indebted to Mr. Brown, the Registrar- General of New Zealand, for the data from which I have compiled the following table. The i-eliable statistics of New Zealand extend from the years 1872 to 1887 inclusive ; these, I think, will be sufficient for our present purpose. Table II. Statidics of Phthisis and General Death-rate, from 1872 to 1887, inclusive. General Death-rate Deaths FROM Phthisis. Deaths from all Causes. Deaths from Phthisis. - Per 1000 per aim. Females Males. Total. Females Males. Total. Per cent, of Deaths. Per 10,000 Population. Otago 10-21 736 1030 1766 8242 12,090 120,332 8-68 8-34 Canterbury 11-99 597 686 1283 8303 10,538 18,841 6-8 8-17 Marlborough 9-88 37 51 88 528 826 1,354 6-5 6-42 Nelson 9-99 111 194 305 1733 2,515 4,248 7-18 7-17 Westland . . 11-35 83 118 201 1101 1,849 2,950 6-8 7-73 Wellington 12-63 343 434 777 4730 6,282 11,012 6-99 8-9 Taranaki . . 10-51 70 87 157 799 1,176 ! 1,975 7-94 8-3 Hawke's Bay 13-24 94 154 248 1387 2,034 3,421 7-24 9-6 Auckland . . 12-59 599 912 1502 7764 11,322 19,086 7-86 9-9 Average for 7-6 8-76 New Zealand PiniHSIS IN NEW ZEALAND. 81 It will be seen, tVoiu this table aiul the first, that the average deatli- rate from ]ihthisis was very sliglitly higher in 1887 than for the years 1872 to 1887. It is also seen that the death-i-ate is above the average for New Zealand, in Auckland, Hawke's Bay, and Wellinirton, in the north, and ])resuuiably the warmer island ; a little lower in Taranaki, in the North Island ; and lower in Marlborough, Nelson, Canterbury, and Otago, in the South Island. In Marlborough and Nelson the difference is a very decided one, and in these provinces, we find that the general death-rate is also lower than elsewhere. It will now be convenient to compare these results with the statistics of Great Britain and Ii-eland, from which most of the white poi)ulation of New Zealand is derived, (jither directly or indirectly, and also with tliose of the other Australasian Colonies, whose ])opulations have a similar origin. I am indebted for the following table to Mulhall's Dictionary of Statistics, and to Hayter's Victorian Year Book for 1885-G, and to the Reports of the Ilegistrai'-Ceneral of New Zealand. Table III. Comparative StaAistics nf Mm-iaiity from Phthisis in Australasia and Grtat Britain. England Kcotlaud Ireland Loudon Victoria Melbourne New South Wales Queensland . . South Australia Western Australia Tasmania New Zealand Ykar, Deaths per 1i),000 Inhabitants. 1850-59 27-30 1870-79 22-05 188(i 17-18 1877 •22-94 1880 21 -Ho 1879 24-76 1861-85 12-98 1884 14-36 1885 14-19 1874-85 22-31 188(5 10-73 1886 14-86 1887 11-43 1886 6-42 1887 11-01 1887 8-95 1872-87 8-76 These statistics are unfaxourable to the Colonies and unduly favourable to Creat Britain, inasmuch as many of the sufferers from consumpdon acquired in Great Britain die abroad, while in the Colonies a considerable proportion of those who die from consumption have acquired the disease elsewhere. Mr. Brown, the Eegistrar-General for New Zealand, notes in his report for 1887 that the exceptionally high rate in Queensland is largely attributable to tlie mortality among the South Sea Island labourers ; and he has, in his returns for 18SG and G 82 IXTERCOLONIAL MEDICAL COXGRESS OF AUSTRALASIA. 1887, shown the length of residence in New Zealand of those who died from this disease. The following are the results for 18SG : — Table IY. Tlie Aaes, vitlt tJie Lewitli of Residence^ of those who (lied frora Phthisis, in 1886, in New Zecdand. I Age AT Death. Len'gth of Residence ? ^' IN THE Colony. S ■" 5 10 15 25 35 45 55 Cm £2 ,Z <:€ to to to to to to to to a s Total. ^t 10 15 2o 35 45 55 05 75 >" c. Ihdo. UniTev 1 month — — — — 1 1 — — — — 2 1 to 6 months — — — 5 2 — 1 — — — 8 (i to 1"2 months — — — 3 1 1 — — — — 5 1 to 2 years . . — — — 3 6 — 1 — — • — 10 2 to '6 years . . — — — 2 10 4 1 — — — 17 3 to 4 years . . — — — 2 3 1 1 — — — 7 4 to .5 years . . — — — 3 ■ — — — — — 3 5 to 10 years — — ■ — 4 11 9 6 1 — — 31 10 to 15 years — — — 8 9 11 3 4 2 — 37 1.3 to '20 years — — — 1 2 5 4 — — — 12 20 to 25 years — — 2 19 20 4 2 — 47 25 years and upwards — — — — 3 7 <» 7 4 — 30 Not known . . — — — 2 2 6 5 — — — 15 Eorn in colony 5 2 4 34 13 9 — — — — 67 Totals . . 5 2 4 C4 (38 73 51 16 8 — 291 Fi-nuaeg. 1 to G months — — — — 1 — — — — — 1 () to 12 months — — — — 1 — — ■ — — — 1 1 to 2 years . . — — — 2 3 — 1 — — — 6 2 to 3 years . . — — ' — 1 1 2 1 — — — 5 3 to 4 years . . — — — 3 3 1 — — — — 7 4 to 5 years . . — — — 1 — 1 — — ' — 2 5 to id years — — 7 8 4 1 — 1 21 10 to 15 years — 2 5 18 9 3 1 — — 38 15 to 20 years — — — 4 2 5 — — — — 11 20 to 25 years — — — 2 7 9 4 2 2 1 27 25 years and upwards — — — 4 2 4 3 1 • — 14 Not known . . — — — i — — 1 — 2 Born in colony 7 7 6 10 30 11 4 — — — — 74 Totals . . 6 12 61 59 38 14 (5 5 1 209 Totals both sexes 12 8 16 :.. 127 111 65 22 13 1 500 It will be seen from this table that 25 '2 per cent, of those who died liad V)een less than Id years in the colony, that 11 per cent, had been less than 3 years in the colony, and that 28 }>er cent, had been born in the colony. I have not the data at hand for coni[>ai'ing New Zealand -,vith the other colonies on this point, but there seems to be no reason to PHTHISIS IN NKW ZEALAND. 83 doubt, that all the colonies sutler more or less from the same cause. Tt is worth noting that Western Australia, which, compared with the other colonies, is isolated from the great stream of European tratlic, has a comparatively low death-rate from phthisis. The following quotation, from Mr. Brown's report for 1S87, shows the present evidence of phtliisis in the native-born population : — " Tlie New Zealand born were, in ly86, in tiie proportion of 51-89 per cent, of the whole ])opulation. If this proportion be api)lied to the mean population in 1887, the result would give ;)0l',4;")S persons, out of 590,374, as having been born in the colony. The total number of deaths fiom phthisis gives a projiortion of 8 •1)5 per 10,000 of the population; of these deaths, 15G were of persons born in the colony. This number gives a pro[iortion of only 5-04: deaths from this cause per 10,000 of the New Zealand born population. The remainder gives a proportion of l.j'17 deaths from phthisis per 10,000 of the population born outside the colony." In order to get exact results on this point, it would be necessary to com] tare the ages of the two classes, viz., the native born, and those born outside the colony. It is probable, that a larger proportion of the native born, than of immigrants, is of an age at which consumption is not connnon. The following table, ta/ken from Mr. Brown's report for 1887, shows the ages of patients who have died from phthisis in New Zealand in 7 vears : — Table Y. ■ The Xumher and Proportion per 100 Deaths from Phthisis in New Zealand^ at each Age Period, for the seven years 1881 to 1887, inclusive. Males. Fe.males. Xi.y. AT Death. No. of Deatlis. Per 100 Deaths from Phthisis. No. of Deaths. Per 100 Deaths from Phtliisis. Under 5 years 50 2-54 55 3-70 5 to 10 years 14 0-71 37 2-49 10 to 15 years 19 1 0-97 64 4-30 15 tu 25 years 401 1 20-42 447 3004 25 to 35 yeais .565 1 28-77 443 29-77 35 to 45 vears 433 22-05 263 17-67 45 to 55 years 308 15-68 119 8-00 55 to (55 years 131 6-67 42 2-82 (15 to 75 years 35 1-78 15 1-01 75 and upwards 7 0-36 2 0-13 Not specified 1 0-05 1 0-07 1964 1 100-00 1488 100-00 Wc may reasonably look for a higher death-rate from i)hthisis, there- fore, among the native born in future years, without any real increase in the development of the disease. To sum up the results shown by the foregoing statistics, it may be fairly said tliat they show that, in New Zealand, phthisis is a less fatal disease to those of European blood, whether born in the colony or immigrants, than it is in the other Australasian Colonies, with the doubtful exception of Western Australia, or in Great Britain and Ireland, from which the bulk of the population is derived. It might 84 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. have been better to have included in this inquiry the whole family of tuberculous diseases, of which pulmonary tul)erculosis is only a branch. But, without going into details, which would make this paper unduly long, it may be said that the same general statement is true of the whole family, as of this, the chief branch. Strumous diseases of glands, of joints, of the nervous system, etc., are as strikingly below the average as phthisis. It is also as well to note that these statistics refer almost entirely to the white population of New Zealand. The Maori and half-caste population are j^eculiarly liable to tuberculous diseases of all kinds, and these diseases are very fatal to them. To what circumstances is this lesser liability to phthisis due ? In the lirst i)lace, much must be ascribed to the climate of New Zealand. Among the few observations on this subject, which come to us from the earliest known period of New Zealand history, are the statements of Captain Cook, and some of those who accompanied him, that among the New Zealanders, disease was practically unknown. The fine physique of the Maoris, still noticeable, was evidence that, in spite of the uncertainties of their food supplies, and their exposure to the vicissitudes of an uncertain climate, the general climatic conditions were such as to favour the development of a race with very high physical qualities. In 1849, Dr. Thomson, surgeon to the 58th Regiment, then quartered in New Zealand, published careful observations which he had made on the health of troo})s serving in the colony. He found that, out of 1000 soldiers serving in New Zealand, 440 were admitted to the hospital for treatment for various diseases, while among 1000 men serving in Great Britain, the number was 921. For diseases of the lungs, he remarks, the admissions wei'e one-third less numerous than among the troops quartered in Great Britain. He also quotes the opinion of Surgeon Pendergast, of the 65th Regiment, who stated, " the climate of New Zealand is peculiarly favourable towards the non-development of pulmonary affections, and, in the majority of fatal cases, the seeds of disease existed before their arrival in New Zealand. Among the five fatal cases in the 58th Regiment, the symjitoms of consumption had been observed in three of them before their arrival in New Zealand." Dr. Thomson also published in his report the following taltle, showing the annual mortality in New Zealand among troops, as compared with other British Stations. (His experience was confined to the North Island) : — Table VI. I I An NUAL Mortality Annual Mortality by PER 1,000 FROM ALL Disease of the Lungs Diseases. PER 1,000. Malta 18 6-0 Ionian Islands . . 2S 4-8 Bermuda 30 8-7 Canada . . 20 6-7 (iibraltai- 22 5-3 Cape of Good Hope . . 15 8-8 Mauritius 80 5-6 United Kingdom 15 8-0 New Zealand . . 10 5-7 IXTERCOLONIAI, MEDICAL CONCIKESS OF ADSTUALA5IA. P Table VII. Meteorologij. — Comfamtim Table of Climate, as observed at the Meteorological Stations in Nem Zealand, during t)te Tear 1886. (iidS'and°£r"'tId). I 1'amp.ratar. from Self-iesistering Inrtrirnient.. Computed fi'om ObBurvationB. Bail. Wind. Cloud Mean. S,mi.r ofD«) .1.1= i.r= 1 Tsmparatuni of Air in Shade. Solar Raitiatiou. Terrestrial Radiation. il 1 ll !§ ft ! i| i|s _o 1 g3 Is"- i s 1. 1 Number of Days it blew from any Point : Morning Obaei-^-ations. fill m 4 4 1 1 ri 1 ; — Stations. 5 If 1 e83q lifi i III ill s' — ' J J, Sis i H a a -Ji -Ji 'f ^•'3 , 1 ' Aiickliind Rotuiua WolUngton .. IJnraln, Caiiter- Dunedlii in. 29 058 20016 in. 30-700. 20 May 30-SSO, 10 April 30743. 20 Hay S0-8S1. ISApril 30840, M,iy ill. 29830, 2 Seiit. 20:250, 2 Sept. 2 Sept. 28-214, 22 Aug. 2805T, 22 Ang. in. 1-130 1-000 1-070 1-0!0 1802 Fah. 501 55-1 64-4 51-9 Fah. 82-0, 22 Jan. 90-5. 23 Jan. 25 Jan. 7 Jan. Fab. 28 Aug, 21 -5, 6 Aug. 32-0, 26 July, 28 Aug. 22 July 30 0, "22 July Fah. 40-0 080 r,4 Fah. ■23-3 121 Fah. 1530, 11 Feb. lSO-5, 8 Dec. 1500, 30 Dec. Fah. 114 2 115-0 Fah. 28-0, 7 July 6,7,28Aug. Aug. 27-0, ■IS Aug. 13-S, ■-'2 July, Fah. 43-7 41-4 43-3 -374 -306 -338 ■288 •289 Fah. 44-5 47-8 43-4 43-7 70 76 in. 32-649 61-790 64-477 52-032 dayg. 169 138 178 1-670, Feb. 3-100, Sept. 3'400, 14 May 16 May 19 Aug. 28 30 3 12 86 63 19 104 93 7 13 19 63 21 62 60 10 13 93 61 114 32 41 109 24 45 23 80 165« 191 218 813,' 8 Sept, .00, 9 Doc. 67.5, 3 Nor. 610, 20 Not. 6^9 *2 5^9 36 j 7 4 14 67 7 27 j 3 18 I 3 1 3 1 ! 8 11 5 19 1, r •Ten inoutha only. PHTHISIS IX NKW ZEALAND. 85 Tn a subsequent ]ia])f'r on tlie diseases of the New Zealanders, contril)uted to the Afci/ico-Chintrf/ical Reviev, in 1854, he says : — ■ " Diseases of the lungs are much more frequent among the New Zealanders than the Englisli. The great prevalence of diseases of the lungs does not arise from the climate, but from causes peculiar to the New Zealanders tliemselves. This I assume, from the comparative rarity of cough and consumption among the European population." I have quoted Dv. Thomson's experience at some length, as the conditions he observed are not likely to occur again, and the results among .soldiers, presumably of the same average tendency to disease, in various parts of the world, ai^e valuable for comparison. The main facts as to the climate of New Zealand are, that there is everywhere an absence of extremes of heat or cold ; that nearly every part of both islands is freely swept by the ocean winds ; that malarial conditions do not exist ; that rain is abundant enough, but not excessive ; that the drainage by rivers is good, and swampy districts are few. There are five meteorological Stations in New Zealand, namely, at Auckland, Rotorua, Wellington, Lincoln in Canterbury, and Dunedin. With the excei)tion of Rotorua, none of these, however, give a just representation of the climate of New Zealand away from the coa.st. The annexed table (VII.), from the Government Blue Book, shows the results of observations at the various stations during the year 1886. The inland climates tlifFer in many respects from those of the coast, but exact observations have yet to be made on the subject. Much of the country occupied by settlers is from 1000 to 2000 feet above sea level. The air is drier than about the coast ; there is less rain ; and the temperature is higher generally in summer, and lower in winter, than nearer the sea. Along the range of moiiutains in the South Island, the climate is that of similar districts elsewhere in like latitudes. The air is fresh and exhilarating ; there are magnificent lakes, rivers, and glaciers to be explored ; but, as the country is little settled in many places, much of it is not avai]al)le for invalids. The table given re[)resents fairly the climate of the coast, but many important points must be left out in such records. Places which are sheltered from the south-west gales are much warmer than exposed places in the same or higher latitudes, and there are many important local varieties of climate in each district. Thus, for instance, the northern part of Stewart Island is warmer in latitude 47° in winter, than Christchurch in latitude 44°. Nelson, Blenheim, and Napier are places whose climates are not represented by any of the statistics as to Wellington, Auckland, »i'c. The west coast of the South Island is only settled in a few places, but there is every reason to believe that the rainfall all along that coast is greater than elsewhere in New Zealand. It is inqwssible in this paper to deal with all the local varieties of climate, but this can be said of every part of New Zealand — that the clii.iate is favoui-able to out-door work and recreation of all kinds, at all seasons of the year; and all kinds of out-door sports are much in favoiu" with all classes. Another factor favourable to health generally, and which tends to reduce the mortality from phthisis especially, is the absence of large towns. The largest population in any one centre does not exceed 50,000 ; SQ INTERCOLONIAL MEDICAL COXGKESS OF AUSTRALASIA. even in tlie largest towns, Auckland and Dunedin, there is very little overcrowding. The houses are, many of them, built of wood, and well ventilated ; often of one story only, and with abundance of open spaces either round about them, or in the vicinity. The drainage is in many cases defective, but on the whole, the conditions ai-e vastly more favourable to human life — as shown by that most delicate test, a low infant mortality — than in the towns and villages of the old world. The social condition of the people must also count as an important favourable item. Good food is abundant and cheap. There is nowhere the grinding jioverty that is to be found in the larger centres of population. Wages, even in depressed times, are high enough to assure, to every man who can work, good food and clothing, and lodging for himself and those dependent on him. Probably, as a consequence of this, drunkenness, and the evils that spring from it, are on the decrease. The nati\e-born New Zealander very rarely drinks to excess, or, indeed, cares much for alcoholic stimulants of any kind. He plays football and cricket, and is interested in all athletic contests ; in tliis, resembling his brother colonists in other parts of Australasia. The occupations of the people must also have an important part to play in their tendencies to disease. In a paper read before the Otago Branch of the New Zealand Institute, by Professor Mainwaring Brown, of Dunedin, in 1888, the number of hands engaged in manufactories is given as 22,102, or 3"8 per cent, of the total population. The total producing population he estimates to be about 101,000, including those engaged in agricultural and pastoral pursuits and mining. In addition, lie estimates t)ther industrial classes, consisting of those engaged in the building trade, labourers, distributors, and others, as about 48,000, As, however, none of the manufacturing indi;stries are conducted under the bad hygienic influences that prevail in large communities, they can hardly be properly compared with those of older countries. The large j^roportion of people engaged in agricidtural and i)astoral work, along with those depending on them, are little disposed to ]ihthisis. But observation of cases seen in practice shows that in New Zealand, as elsewhere, jjhthisis is often produced i]i the workshop, the compositors' room, and in coal and other mines. The settlers, as a rule, were drawn from a healthy class. This may be said to be counterbalanced by the fact, that the Colony has also attracted a large number of families predisposed to tubei'culosis ; and also, that along with the good colonists, many of another stamp have been introduced, by unwise innnigration laws and other influences. TJie main practical deductions that I would make from the facts stated are, that the native-born ])opulation of European blood of New Zealand, and the imnngrants of Europe;in birth living in New Zealand, are less subject to phthisis than their fathers, or than those who are born in or settled in other Australasian Colonies, and that the causes of this are mixed, but are mainly that the population, as a whole, is well fed, well cared for, and has abundance of i)ure air to breathe. The curious fact that the JNIaoris and half-castes are s]jecially vulnerable to tuberculosis, is cajjable of explanation by several lines of facts. In the first i)lace, all the .South Sea natives, brought into contact with Europeans, seem to ac(]uire tuberculosis and infectious diseases easily and viiulently. This is also noticeable among the aboriginals of TKEATMENT OF IMITIIISIS liV CLIMATK. 87 Australia. It is, doubtless, due to the fact that tuberculosis is, to a certain extent, an infectious or bacillary disease. The altered habits of the natives, their dirty habits, their prolonged idleness, and csjiecially their custom of congregating in large nund)ers in close, ill-ventilated huts, where they breathe the same air over and over again, are among the most imjjurtant jjredisposing causes. Dr. Hocken, of J)unedin, who has had a lai-ge and exceptional experience of New Zealand, informs uie that he is of opinion that the adoption of European blankets and European clothes, instead of the native flax mat, is a ])Owerful predisposing cause. The native gets overheated in the unaccustomed garments, throws them otF, and becomes chilled and depressed in consei^uence. It seems to me not unlikely, too, that the fact that tuberculosis is a new disease among them, may account partly for its fatal etiect. European populations have been fighting this and other infectious and constitutional diseases for centuries, and are, to a certain extent, protected iigainst them. There has been no such contest among the inhabitants of the Oceanic Islands, until comparatively recently isolated from the outside world, and consequently there has been no such protection as Eui'opean populations have acquired. It is no part of the scope of this jmper to discuss either the pathology oi" the treatment of consumption. [ believe that the part, played by the bacillus of Koch, is analogous to that taken Ijy the torula in yeast fermentation. It needs, like the yeast torula, certain conditions for its development, and these conditions have been hitherto called, and I think justly, the causes of consumption. That many of these conditions are absent in New Zealand is, I chink, the chief reason for the smaller mortality from consum})tion in tiiese islands. It cannot be too strongly urged, that there is no specific in the New Zealand climate which will cure advanced cases of phthisis. The range of climatic treatment is limited here as elsewhere, and I will only add my ])rotest, to that of others, against the crUelty and uselessness of recommending a sea voyage, and residence in the Colonies, for a very large number of the cases of consumption which come under the notice of physicians at Home and elsewhere. TREATMENT OF PHTHISIS BY CLIMATE. By DuxcAX Turner L.B.C.S. Ed., L.R.C.P. Loxd. Within th(j last twelve montlis, I have seen a number of patients who had resided, some of them in winter and some in summer, in the higher jjarts of the Alps, chiefly St. Moritz. They were unanimous as to the benefits tliey had dei-ived from their sojourn there. 31any of them had visited other resorts, but they all gave the jneference to the high altitude stations. The })rincipal drawback, with respect to Aljiine health retreats, is the expense. It is not a treatment that any poor man, or even a ])erson with a moderate income, can adopt. And many jjoor jjeople, or those of limited mean.s, find their way to our .shores in tJie hojje (alas! too often delusive) that they can regain liealth, and at the same time earn a livelihood in our genial climate. 88 IXTEKCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. The oliject of this paper is to refer shortly to the Australian climates suitable to consumptive invalids. In order to bhorten as much as possible my remarks, I will sketch briefly the necessary information. The inhabited ]iortion of settled Australia may be divided mainly into three divisions — the littoral, or shore division, which is at present the most populous ; the great mountain chain, commonly called the Dividing Eange ; and the great inland plains beyond. The first of thes-e may be dismissed at once, as it is generally acknowledged that, with the exception of a few sheltered nooks on the coast, it is entirely unsuited to the phthisical invalid. The mountain chain is of more interest to us, although, so far, a great deal of it is practically so little known that we can only speak of a few mountain localities where real settlement has taken place. In comparing our mountain regions with those of Europe, Asia or America, we are at once struck with the fact that our mountains are generally so restricted in height, that the high altitude treatment can never be carried out here in its entirety. • But, taking them for what they are, I believe that they have been strangely overlooked by medical men in this country. In recommending to patients, Avho cannot take a sea voyage, a suitable residence in summer, where can we send them to, unless it is to the mountains 1 Unfortunately, the accommodation at most of our mountain resorts is entirely inadequate to the wants of an invalid patient. Also, our information res^pecting the climates of the most elevated, is meagre and unsatisfactoiy. For some time past, I have been making inquiries in this direction. The highest settled parts of Australia are, the Blue Mountains, near Sydney, and Mount Macedon, near Melbourne. Tliese places have not, as yet, been specially recommended to chest sufferers, but I may mention that I have myself known several patients to be much benefited by residence there. And in, at least, two cases there was apparently perfect restoration. With the exception of a few towns in New South Wales, there are no settled districts in any of the colonies at a sufficient elevation to afford relial)le data on the question of the immunity of the inhabitants from phthisis. To the practitioners of these towns, however, I addressed some time ago a few questions. The majority of the communications were obligingly responded to, and 1 will now give a brief .sketch of the replies. From Bathurst, 2153 feet above sea level, Dr. Basset writes: — ''In a practice of twenty-five years, I have only seen about six cases of phtliisis originating here. In this nundjer, I don't include aboriginals." From Crookwell, near Goulburn, 3000 feet above sea level, Dr. A. E. Fitzpatrick writes : — " In a practice of over four years in this neighboiirhocd I have not seen a single case of phthisis, nor haA'e I heard of one." From Bowenfels, close on 3000 feet above the sea, Dr. Asher writes : — " I have seen but one case of jihthisis that originated here, and in that case the ))atient recovered." From Armidale, New England, 3300 feet above sea level, Dr. INlallam writes : — " I do not know of any case of phthisis originating in our tow}i or neighbourhood. My colleague. Dr. Wigan. who has been l>ractising heie for thirteen oi- fourteen years, says he has never seen a native-born New Englander develo{)ing i>hthisis." TlilCATMKXT OF PHTHISIS ISV CLIMATK. 89 From Walclia, another town of New England, 3300 feet above sea level, Dr. Boodle writes : — " In nine years' pi-actice I have seen but one case of jththisis, in a yellow boy, and he recovered." I might give you more of these extracts, but they are all much alike, and go f:ir to prove that in this country, as well as Euroi)e and Amei'ica, the inhabitants of high altitudes have a remarkiil)le immunity from phthisis. As yet, no attempt has been made to found a mountain sanatorium in Australia. Toowoomba, in the Darling Downs, Queensland, has the nearest approach to one. Its winter climate is delightful, but the altitude (barely 2000 feet) is insutiicient for rarefaction of atmosphere. In the Australian Alps, however, tliere are several elevations equal to that of Davos Platz, or St. Moritz, in Switzerland ; but, as yet, there is no accommodation for invalids. This time last year I spent a week at the Hospice, near Mount Hotham, in the Australian Alps, in Victoria. The old man who ke])t the house of accommodation for travellers had lived there, I think, 20 years. His })owers of observation concerning tlie weather were not of a high order, but, from what I could gather, there are several months of winter there, especially if the weather happens to be dry, that are very much like the weather recorded in the celebi-ated DaA'os Platz. The altitude is exactly the same as that of the famous Swiss resort. tTnder any circumstances, this would be a delight- fully cool place for invalids during the summer months. Rarefaction and sunlight would be the same as at .similarly situated stations in the Swiss Alps, which are proved to be highly beneficial. It is to be hoped that ere long Victorian enterprise will })rovide adequate accommodation in this beautiful spot, which, I have no doubt, would be soon largely patronised. I have merely given this sketch in order to direct the attention of Australian practitioners to the advantages of mountain climate — advantages which, so far as I am aware, have not been touched U[ion as yet by any local medical writer. The last climate I will refer to in this paper is that of the great inland plains of Australia. This climate is so well-known to most of you, that it will not be necessary for me to enlarge on its properties. Briefly, it may be described as something between the climate of the Riviera and that of Egypt, dryer than the former, but not quite so dry as the latter. Its chief recommendations to the chest invalid are — dryness, plenty of sunshine, and moderate temperature, thus enabling a patient to pass a great deal of his time in the open air, a most important i)art of treatment in phthisical cases. That hundreds have recovered from passing two or three winters in Riverina, I have no doubt. I have myself known several instances, and other Melbourne practitioners have done the same. The great plains are so much alike, that there is no need to mention any [jarticular locality. In Victoria, we send our patients to Echuca or Deniliquin for the wintcn-. If the rain maps can be depended on. the districts of Swan Hill and Wentworth are the driest of the Riverina district, and possilily a sanatorium may start up at one |tlace or the other at some future time. In giving a brief resunu' to this pa))er, I may state that I consider the ocean cliuiate the best. After that, the high altitude climate at or above 3000 feet. Thirdly, comes the climate of the great inland plains. Lastlv, there is the climate of the marine resorts. 90 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. THE r)PEN-ATPt TREATMENT OF PHTHISIS. By James- P. Ryan, 3I.K.Q.(J.P.I., L.R.C.S.I. Chevalier of tlie Legion of Honour. Graves says: " It is of great im})ortanee to know liov/ to make a man plitliisical, as, by pursuing an opposite line of conduct, we shall be able to prevent it," and, I may add, to cure it. Xow, what are the conditions of living which tend to produce phthisis 'i They are mainly such as cause an impaii*ed condition of general health, and a l.owered vitality. Amongst these, ovtrcrou'Jiny and impiii-e air hold the most important positions. We know that men may be subjected to great hardships, such as exposure to wet and cold, want of food and rest, fatigue, etc., without running the same chance of falling victims to phthisis, as if they were huddled together in a confined space, and, though supplied with a sufficienc}' of wholesome food, were deprived of fresh air and exercise. And this applies not only to man, but very largely also to the animal kingdom. Villemin, in the course of his experiments, found tliat guinea pigs which were kept crowded together had less power of resisting tuberculosis than those Avhich were allowed more space and air. Aifections of the respiratory organs are far moi-e prevalent amongst stabled horses, than amongst those that are running out. Experience, from all time and in all places, goes to show that those who lead an outdoor life are more robust, and less prone to lung diseases, than those whose occupations confine them within doors. I am informed by those who knew the Australian aboriginals well, that phthisis used to be very uncommon amongst the wild or half-civilised ones. Those who adopt the customs of the white man, easil\- fall victims to it. The Araucanian Indians, whose country — a level plateau some hundreds of feet above the sea — lies in the southern part of the Sjtanish-American Republic of Chili, are seldom affected with phthisis. I believe I am correct in this statement. I lived close to their frontier for some years, and my information was obtained by personal observation, as well as by incjuiry. On the other hand, amongst their neighbours across the border, the Chilenos, the disease is widely prevalent ; and markedly so, of course, amongst the dwellers in towns. I attribute this to the fact that the Chilenos are morbidly sensitive to cold — almost every ill that flesh is heir to being jiut down to an " aire " or draught ; and air, being thus looked upon as an enemy, is carefidly excluded. Hirsch says that " phthisis is tmknown among nomad tribes, such as the Kirghiz of the Central Asian Steppes, or the Bedouins of Arabia,, until these ])eopl(' settle in towns." The same imu) unity from phthisis is observed in the dwellers on high mountains, due, without doubt, to the sparse population, and the active outdoor life which they lead, as well as to the purity of the atmosphere which they breathe. As soon as they congregate together in towns, the iunnunity is lost, and the disease is found to prevail at (^uito, Cuzco, and Potosi, which are resjiectively 10,000, 11,000, and 13,000 feet above the level of the sea. Dr. Guy found that of lOi comjjositors who worked in rooms having less than ."'(.)(j cubic feet of air s})ace for each person, 12 jjer cent, had THE OPEX-AIll THKATMKXT OF PHTHISIS. 91 had blood-spitting. In 100 who worked in rooms having a capacity of more than GOO cubic feet for eacli person, only 2 per cent, suffered in this way. Dr. Eansome, in his paper on " Tubercular Infective Areas," read before the Epidemiological Society in 1887, referiing to Salford, says :— " In certain streets and courts, consisting of back to back houses, unfurnished with through ventilation, tubercular disease was much more common than in other jjarts of the same town ; and such disease occurred again and again in the same houses." And this w^as subsequently fully confirmed by a report made to the Local (lovernment Board by Dr. F. W. Barry and Mr. Gordon Smith. The day has passed when physicians pinned their faith to medicines in the treatment of this disease ; and of the numerous remedies, from the hypo])hosphites to Bergeon's gaseous enemata, which have been vaunted as specifics for consumption, not one, excepting perhaps cod liver oil, has enjoyed anything beyond an ephemeral reputation. Instead of concentrating the attention on the local symptoms, as was formerly too much the custom, the modern physician addresses himself to repairing and strengthening the constitution of his patient, by sending him to the country and telling him to eat well, and be as much as possible in the open air. The few lucky ones who can afford the expense arc recommended to try the mountains of Switzerland, or the high lands of the Cape, or they are ordered u})on a long sea voyage ; and, without doubt, the "mountain" and the "sea" cure, as they are called, have often been attended by the happiest results. In the early part of the present year, Dr. Theodore AVilliams gave the results of the treatment of 141 cases of phthisis in his practice, by residence in high altitudes, 5000 to 9000 feet above the sea, and in 70 per cent, great improvement took place, whilst in 30 per cent, there was complete .irrest of the disease. Many are relieved, and their lives are prolonged, if they are not cuved, by a residence on the table-lands of South Africa, or in the Australian bush. What then is it which has so beneficial an etiect upon the consumptive patient, and which is found upon the mountain top, on the sea, and in the desert ? Without any doubt, it is pure air. The number of bacteria in a given (juantity of air is the best test of its impurity ; and in this light, the following table is interesting, as showing the result of observations made by Miquel on the Swiss Mountains and in Paris : — At an elevation of from 2000 to 1000 metres, in 10 cubic metres of air On the Lake of Thun, 560 metres Near Hotel Bellevue, Thun, 560 metres . In a room of the same hotel In the Park of Montsouris, near Paris In Ptue de Eivoli, Paris It would be intere.sting to know the result of an examination of the air of a house in that street. And so, also, the atmospliere above the ocean, in forests, and in the desert, as gauged by this test is nearly, if not quite, pure. Tlie tssential condition for success in the treatment of consumption is, that the patient be kept constantly surrounded by the purest possible 55,000 •) 92 INTERCOLOXIAL MEDICAL COXGRESS OF AUSTRALASIA. atmosphere. In tlieoiy, this is perhaps admitted by a hwge numl)er of medical men, but in practice I am quite sure tliat the principle is not carried out sufficiently far. Dr. Russell Reynolds, in his " System of Medicine," gives sensil)le advice about diet, exercise, bathing, &c., and speaking of a pure atmosphere, says : — " The grmt end he (the physician) should aim at is, to surround his patients with as much pure air as possible, consistent with warmth and absence of draughts. In summer, [lood ventilation should be secured by letting down the windows an inch or so at the top." I presume he means the bedroom windows at night-time, though he does not say so, and he is silent about ventilation in ii'inter. Coming from such an authority, this may, I presume, be taken as a fair example of the prevalent idea held by medical men, or, at all events, by many of them, of surrounding a phthisical patient with pure air. Cthers suppose that, by keeping the window^s w^ell opened during the day, they secure a supply of fresh air for tlie night ; a mere delusion, I need hardly say, though it is better than excluding the air both by day and by night. The patient should be constantly surrounded by ])ure air. This is the ideal, but it is scarcely attainable in practice, though, under favourable conditions, we may come near to it. Conjure u]i for a moment the actual surroundings of an ordinary phthisical })atieiit. He is in a chair, or in bed, in an apartment which is at the same time his sitting-room and bed chamber. Even in fine weather he wears an unnecessary amount of clothing, including two or three shirts, which are not too frequently changed, and a chest protector of wool or chamois leather. His bed coverings ixre soaked in foul- smelling sweat, the windows are closed, the chimney stopped up, and he is inhaling, during the greater part of the twenty -four hours, an atmosphere reeking with impurities. I ask you, is it reasonable to expect favourable results from any mode of treatment in a patient with such surroundings 1 The first necessity, then, is that the consumptive be constantly, both by day and by night, in the purest possible atmosphere. Where it is feasible, send him to the mountains, to the desert, or on a long sea voyage ; but tell him that, in oi'der to obtain the greatest amomit of benefit under such favourable conditions, the air which he breathes during the long hours of the night should be nearly, if not quite, as pui'e as the atmosjihere by which he is surrounded during the day. Unfortunately, by far the largest number of those suffering from jihthisis are debarred, by want of means, from resoi-ting to the mountain or sea "cure." But many might live in the country, instead of in town; or in a suburb, instead of in the midst of a crowded population ; and even the condition of the denizens of the lanes and alleys may be improved, and they may be helped on towards recovery by imi)roving their surroundings. The fear of air, and paiticularly of night air and cold, entertained by the patient and by his friends, is groundless, and must be coni])ated. Many i)hthisical patients are morbidly sensitive to the slightest cold air or wind ; but this is ])roduced in some, and in all greatly j\ggriivated, by over-clothing, and remaining indoors in a close atmosphere. This hyper-sensitiveness of the skin and bronchial mucous membrane is surely and rapidly lessened by te})id or cold ablutions, followed by frictions with a rough towel or brush, and 1y being in the open air. PNEUMATIC THERAPEUTICS RY MEANS OF P0UTA15LE APPMJATUS. \j'., Not 80 very long ago, I was opposed to the establisliment of special liospitals for the treatment of consum])tives, but I have come to recognise the hopelessness of their condition, as patients in a general hospital. They enter such, not to get better, but to die. But even our general licspitals miglit be so improved as to be made more suitable for such patients, by the addition to them of wide verandahs, where those who could not walk about, or sit in the gardens (I assume the existence of such), might lie in the air all day long, and all night long in fine weather, as is the custom in the Augusta Hospital at Berlin ; or else tents, or summer houses of light porous material, should be erected in the grounds, which might be occupied during the sunnner months, if not all the year round. Time will not permit of my entering into details of the most suitable sites for, and the best mode of construction of, special institutions for the treatment of phthisical patients. In Victoria, the sea-side lias many advantages, not the least of which is the possession of a tolerably equable temperature throughout the year, and a background of wholesome scrub or forest country. The arrangements in such an institution as the National Hospital for Consumption at Ventnor, England, particularly in the new part of the buildings, are, on the whole, excellent. It consists of blocks, each to accommodate 12 patients, each patient having a separate sleeping apartment. Then there are sitting and dining rooms, large balconies, and a system of ventilation partly natural, partly artificial, by which 5000 cubic feet of fresh air, at a temperature of 62^ Fahr., is supplied to each patient per hour. Of course, all this means the expenditure of very large sums of money ; ami yet it is exceedingly probable that Ijetter results might be obtained from housing the patients in tents, huts, or in other light iMiildings constructed of porous material. Whatever objections, on the score of coldness, may be made to tliem in the countries of Northern Europe, where the winters are long and severe, such objections cannot be valid here in Victoria, where, by comparison, they are short and mild. But in reality there is no difficulty whatever in warming the interior of such constructions by means of open fire-places, stoves, and other appliances, which may be utilised without taxing too severely the ingenuity of the architect or the medical man. ON PNEUMATIC THERAPEUTICS BY MEANS OF THE PORTABLE APPARATUS. By V. Mar AND, M.D., K.C.L Consulting Surgeon to the Sycluey Benevolent Asylum, etc. The article which first drew to this subject the attention of the Australian pi-ofession, if I am correctly informed, was ])ublished by ma in the Australasian Medical Gazette for September 1886. It made no pretensions to completeness, and was written with the ho))e of encouraging the adoption of a partially, if not wholly, neglected inode of treatment. My remarks, on the present occasion, are intended to apply i)rinci]>ally to aero-therapeutics — that is to say, to the mechanical treatment of 94 INTERCOLONIAL MEDICAL COXGRESS OF AUSTRALASIA. certain affections of the resi)ii-atorv organs by means of alteration in the jiressure and composition of atmospheric air, applied liy ajiparatuf. that will act on the pulmonary surface only, or on this and on the general surface of the whole body at the same time. The a]>paratus used for carrying out the above principles are various. Later on I will mention those used by me, and among the veiy many others, I will make S])ecial mention of the one used by the American ]ihysicians, called by them the difterentiator, and its action pneumatic differentiation, which is thus descriljcd b}- its inventor, Dr. H. F. Williams, of Brooklyn : — ■" It consists in immersing a patient in a partial vacuum, thereby removing to a sufficient degi'ee the external pressure of the atmosphere, and at the same time supplying the lungs with air at its normal pressure, and to a greater or less extent impregnated with the substance which it is desired to administer." Though at tirst siglit different, yet is the differentiator the same in its effects as the administration of compressed air, the superiority of the apjiaratus being the facility and thoroughness with ■which remedies can be carried into the lungs. The Atmiometer of Professor Jacobelli is an apparatus quite different from all others, and almost perfect, with which we can carry out this mode of treatment according to our most advanced knowledge. It is very comi>lex ; in fact, is a combination of different apparatus, each having special purpose, while all harmonise to form medicated atmospheres, and convey in definite (quantities into the different organic cavities, normal or patho- logical, any drug in the shape of spray, of varying fineness, or of impalpable powders and solutions, having as menstruum the air compressed or rarefied, or water for those cavities that tolerate it. By whichever apparatus compressed air is received into the lungs, ue have — First, a greater pressure acting on the superficies of them than the one acting on the superficies of the body. This high-pressure air will comi)letel3^ distend the lungs and expand the thorax. 8econd, this positive pressure on the pulmonary surface will aid the action of the inspiratory muscles, and so facilitate inspiration itself. The effect of in.spiration, under these conditions, is a greater dilatation of the lungs anil thorax than can be brought about even with the deepest natural inspiration. Waldenburg has proved by expei'iments that a sti'ong healthy man. after the deepest inspiration of atmospheric air, measured across the chest 98 centimetres. After inspiration of air comjiressed to + -^yX) atmosphere, the measurement was 100 centimetres, and when the air Was compressed to -F J- atmosphere, it was 101 "5 centimetres. Then, again, it has been calculated that the quantity of compressed air, which can l>e forced into the lungs, may amount to 1000 centimetres more than the quantity taken under the normal atmospheric pressure. The ultimate results of the two factors mentioned, viz., increased intra-pidmonary ]iressure, and increase of respiratory air, will be an increase of the vital capacity of the lungs. Again, the respiratory air, in consequence of its greater volume and tension, offers a greater resistance to the elastic tissues of the pulmonary cells and to the expiratory muscles — hence, a niore copious removal of the resi)iratory air, and an increased activity of tlie ventilation of the lungs; that, of course, is if the pressure of the condensed air is not so great as to overcome the natural elasticity of the lungs, and cause emphysema. PXEUMATIO THHKAPKUTICS BY MKAX.S OF POiri'AlU.K APPAIJATL'S. 95 On tlie otluT hand, l>y expiration into rarefied uir, we can olitain the following eftects : — Removal of larger qnantities of air fr.ont the lunos than in ordinary expiration (from a few hundred to 10(tO cubic centi- metres) ; an acceleration of the exchange of gases, hy the pumpin" out of a considerable portion of the residual air, charged with carbonic acid, and the admission of a largei- quantity of atmospheric air, charged with oxygen ; diminution of the circinnference of the thorax, the retraction of the lungs, the increase of the inspiratory and expiratory force, the augmentation of the vital capacity of the lungs (Oertel). So by this method we can remove dyspnrea, which is the result of expiratory insutiiciency, as is the case with emphjsematous })atients, who at once feel a progressive relief, and leave the apjmratus without a trace of dyspna?a. Of the effects on the circulation, as well as of the chemical effects of acro-therapeutics, I will simjily say that the former are the same as in normal respiration, only altered in jjroportion to the extent of condensation of the air, and the mechanical force brought into play by it ; and the latter by the quantity of ox\'gen absorbed, which will produce a more active state of nutrition. These are effects apart from those caused by the action of the remedy, with which the air may be charged. From what precedes, it is easy to see that this method has a large range of a[>plication, in the treatment of the various diseases of the lungs. Out of the whole number of cases (about GO) treated l)y me with this method, I had written the history of 36, which 1 at first intended to read as an appendix to this paper j but this being already lengthy, I am unable to do so. Twenty, however, of the 36 cases were, with description of apjjaratus used, etc., published in the Austrdlasian Medical Gtndte for November 1887. The remarks that follow are based chiefly on the clinical results obtained in those 36 cases, which are thus divided : — Asthma ... ... ... ... 4 Acute bronchitis ... ... ... 3 Chronic l^ronchitis ... ... ... 4 Premonitory and fii^st stage of phthisis ... 10 Chronic phthisis ... ... ... Acute phthisis ... ... ... 1 Chronic pharyngo-laryngitis ... ... 2 Chronic Ehinorrhcea ... ... ... 1 Acute exudative pleurisy- ... ... 1 Pleuritis adhesiva clironica ... ... 1 36 Of the four cases of asthma recorded, one did not tolerate the mechanical treatment, the other three received the most marked benefit from it. Case No. .^» found relief from all the painful symptoms of dyspncea only by the use of compressed air, the usual remedies having failed to do so. In this, as well as in case No. 31, the inspiration of compressed air was directed against the mechanical processes arising out of the occlusion of the bronchi, and the asthnui was cut short by forcing- air behind the stenosed parts of the lungs, and thus renewing tlie 06 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. arrested exchange of gases, and preventing the inflation of the air cells by preventing the i-arefaction of the air within them. No. 2'J l)ad been a martyr to the disease for nearly ten years, and it is needless to state that all known remedies had been used by him. Before the treatment was commenced, the ap})roach of a storm, a change in the weather, would have invariably brought on an attack. After dinner he would be obliged to sit quiet for a couple of hours, was unable to carry on his ministerial duties, and was unable to walk any distance, ttc. After the treatment had been continued for a few days, he showed signs of improvement, and now he can go out in any weather, conduct two services in one day, go about his business, and, but for an occasional approach of an attack, he would consider himself (juite cured. In this case, rarefied air was not tolerated, though there was slight emphysema. In this case, the compressed air was medicated with menthol, 1 in GO of alcohol ; in the other two, witli ol. jjini silv. Of the effects of aero-therapeutics in bronchitis, my ex)>erience confirms the statement reported in my first paper, viz., that all cases could be easily cured by this method ; that the moderate expansion of the lungs relieves the constriction complained of in this disease, and expectoration is soon rendered easy without the aid of those disgusting compounds known as cough mixtures, about which (expectorants) no less an authority than Prof, Aust. Flint writes (" Flint's Practice of Medicine," p. 221) : — '• They are of doubtful eflicacy, and if not useful, are less or more harmful. Squills, ipecac, syrups and opiates belong to the relics of bygone daj's." The effects obtained in case No. 28 were surprising. He was almost cyanotic when he first came to my rooms, the cough was sim]»ly disti'essing, and he was almost exhausted from want of sleej) and food. He improved rapidly, and was able to leave town after a fortnight, feeling "as he had never done for the last ten years." The chief Ijenefit to be derived by the systematic treatment of bronchitis with this method is, the expansion of the pai'tially collapsed cells, generally left by the disease, the collapse leading to subsequent attacks, and often becoming the advanced agent of phthisis. Against which last-named disease, aei'O-therapeutics is the most potent agent which we possess. It is hardly necessary for me here to state, that consumption (laryngeal or pulmonary) in all its stages, is curable, this proposition being now beyond the argumentative stage. In the Jjntish Medical Journal for Novemlter 17tli last, .Sir JNIorell Mackenzie writes : — " I, who have also been of ojnnion that laryngeal phthisis w^as in point of fact incurable, must now admit that the 2)0ssi!)ility of cure, even in unfavourable cases, has been fully established." If tubercle is curable in the larynx, why should it not be when in the lungs, the lesion ])eing in both cases the efl'ect of the same virus, i.e., tubercle bacilli ? Antiseptics are the therapeutic agents that cure laryngeal tuljerculosis, antiseptics must be the chief remedies that eventually will be found to cure the other manifestations of the bacilli tuberculosis on the respiratory organs. I do not believe in being an enthusiast in matters relating to therapeutic investigations, yet I cannot approve of an exaggerated sce])ticism, as it will only lead to nihilism. Let the idea become ])revalent that phthisis is incurable, and nobody will ever think of excogitating a means to relieve the unhapi)y suflx;rers from this fell disease;. PNEUMATIC THERAPEUTICS BY MEANS OP POKTAELE APPAKATUS. 97 Natural!}-, the treatment for consumption of the huigs cannot be so efl&cient as that for tubercle of the laiynx, as we are unable, in the former, to avail ourselves, with antiseptics, of surgical operations in removing the causa riiorbi. This effect we may obtain in phthisis by means that will destroy the germs of tlie disease directly, ancl by others that will do so indirectly — tliat is to say, by antiseptics, and by raisin'^ the general standard of nutrition, and otherwise renderino' the lunf tissues sterile, or unlit for the ])roliferation of the said germs ; or stronjr to isolate those parts already destroyed, and render them innocuous to the adjoining tissites. Aero-therapentics is the only means, in the present state of our knowledge, by which we can carry out the above princi])les of treatment most efficiently. It is certainly the best substitute for the climatic treatment ; in fact, I do believe that this will ])rove curative only when the density of tlie air is so changed as to induce the effects above mentioned in the respiratory organs. Permit me to very briefly relate the following history of a case, which bears on this point : — ^E. F., 29, ironmon^-er ■with history of consumption in his family, and with short cough, loss of weight, energy, and strength, consulted me in 188G. Had sul>crepitant rales anteriorly and posteriorly over left apex. The ordinary treatment ■was ordered, tvifh chcinains in directing the patient's diet. Even in cases where temporary relief only was ]3ossible, it has been a substantial one, life having been continued for many months in comparative comfort, when there seemed nothing but the release of death left at the time they commenced treatment. I have now only a few remarks to make aV)Out the use of compressed air while hemoptysis is present. I have used it in all cases of moderate severity — that is to say, whenever patients expectorated some blood mixed with phlegm, or pure, in mouthfuls. I only adopt the precaution of using moderate pressure at first, and few cylinders, the blood always disappearing after a few days. In my cases, you will find that I have used aero-thei'apeutics in many more diseases of the respiratory oi-gans, even in a case of chronic rhinorrhcea, in which it was employed with a view of relieving the large bronchial tubes from their share in the affection, but it succeeded in stoi)jnng the secretion from the nasal superficies of glairy nnicus which, previous to the treatment, amounted to about two or three tumblerfuls l)er day, but was soon reduced to one-third, the bronchial symptoms disappearing altogether. The air was medicated with menthol solu- tion, 1-40. 1 TIIR IMMKDIATK TUHATMENT OP PLEURISY WITH KFFUSIOX. 99 ON THE IMMEDIxVTE TREATMENT OF PLEURISY WITH EFFUSION. By S. DouGAN Bird, M.D. Fonucrlj' Lecturer on Medicine in the University of Melbourne. The subject of this short paper is limited to one pliase of the trciitmeut of one morbid state. It is this — Given a patient, otherwise normal, sutiering from that very common disorder, sudden intlammatory eti'usiou into a ])leural cavity, is it not only ])Ossible and permissible, but tlie soundest and best practice, to cure him at once, clto, tnto et Jc.cioide, by drawing off the fluid, instead of waiting for Nature to remove it by the tedious and somewhat uncertain process of a1)Sor[)tion 1 I contend that it is, and have so done for the last twenty-ti\e years, with the result that I have never had to regret early tai)i)ing, but .several times have bitterly regretted being over-persuaded to delay it. It is hardly necessary to refer to the history of thoracentesis, which the older writers, and indeed, some of more recent times, looked upon with holy horror, as a last resource, somewhat on the same platform as craniotomy, or the Ctesarian section in midwifery. Let us come down to our own times. We may search all the special treatises and all the dictionaries of medicine in all languages, and we will find nothing about the immediate treatment of pleurisy with effusion, but only blisters, iodine, mercury, strapping, even that refinement of cruelty, the " thirst cure," and so on, for seveial pages, while the unluck}^ patient is losing time, money, flesh, and faith in his doctor ; and it is not till the next chapter, when losing all patience, he may be supposed, like a woman in labour, to be begging for "something to be done," that the question of this simple little procedure is entertained at all ! But some may say. We now know that pleurisy is not the fatal disease which our venesective ancestors supposed it to be ; therefore, why interfere, when doubtless a large proportion of cases undergo natural recovery 1 True ; not innnediately fatal, but left to itself, or medically treated, it is often a prolific parent of e\il. How often do \\G see hopelessly collapsed lungs tied down by old adhesions, which \N ould have been prevented by early interference ? How many phthisicals, who can trace back their illness to expectantly treated pleurisy with eftusion, which not only kept their lower lobe squeezed and useless till it was ho})elessly impermeable to air, but lowered their general vitality so much by confinement and starvation, that the ever- ready bacillus pounced on them as congenial homes'? Such ca.ses are not so common now as they were twenty years ago, for obvious reasons ; but they are by no means rare, especially in new arrivals from Europe in search of health. To my mind, the early drawing off of pleuritic eftusion, to sa\'e the patient from after ill effects, is as sound treatment as the early division of stricture in strangulated hernia, instead of waiting till the gut is on the vei'ge of gangrene ; or the inunediate reduction of a dislocation, instead of waiting till the head of the bone has contracted adhesions in its new position. In each of these three morbid states, we have inq)ortant organs displaced by sudden and unnatural conditions, which are liable to do them permanent injury. Surely then, if these II 2 100 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. conditions can be removed by simple and liarmless means, as in our present subject, the sooner this is done the better ; as the duration of the iUness is reduced from weeks or months to days, the consequences of prolonged pressure are avoided ; and last, not least, the chances of the degeneration of the fluid into pus are reduced to a minimum. If the object of sound medical and surgical treatment be to assist Nature towards natural cure, surely immediate tajjping with a small trocar (provided that meddlesome and dangerous apparatus, tlie aspirator, is not superadded) exactly does so in these cases, and does it quickly, safely, and with no more pain tlian that of a pincli or the pi'ick of a pin. By immediate tapping, I mean rather so in comparison with the old plan of unnecessary and even blameful delay. We do not often have a chance of seeing a case of pleurisy from its very inception ; but there can be no doubt that when the aoute pain ceases suddenly with the friction sound, this is directly caused by effusion separating the inflamed surfaces. So far, so good. If this effusion were always limited to a layer of fluid just sufficient to prevent friction, it would, no doubt, be rapidly absorbed, and is so in many cases that never seek medical advice. But in a considerable percentage this does not happen, and the efi'usion goes on. However heretical it may seem to philosopliers of the Paley school, it is no uncommon thing for Nature's salutary ])rocesses not to stop when they have done their work, but to go on blindly, so to speak, till they push the original disease into the background, and become themselves the leading feature in the case. This we often see in haemoptysis, which, trying to relieve a gorged lung to the extent of a few ounces, overdoes the matter to the extent of a few pints, and leaves the patient bloodless, and at death's door. So again, in the critical discharges from the great emunctories, at the turning-point of feveis and acute inflam- mations, wlien the highest skill of the physician is called for to decide whether he shall interfere, or hold his hand and stand by as a s])ectator. So, in our present suliject. If absor|)tion rapidly takes place after pain ceases, and the rested and blandly-cushioned surfaces of serous membrane have had time to recover themselves, leave well alone by all means ; but if by examination we And that the fluid is either stationary or increasing, the time for interference has come. It is delay, and not action, that is dangerous, and tapping should be i-esorted to at once. I have not found that pyrexia need be a bar to this ; in fact, the temperature often falls on removal of the fluid. The next thing we have to consider, is the method of operating. To begin Avith, any suction apparatus is not only useless, but liarmful, and its use is as foolisli and unscientific as it would be for an engineer to erect complicated and expensive pumping gear for the draining of a mountain loch into the valley below, when ho need only cut a channel or tunnel, and use the natural fall. Besides, the asi)irator acts too rapidly and forcibly, and gives the lung no time to expand, and has been known even to burst it, and cause pneumothorax. A tolerably fine trochar shoidd be used, as the patient lies on his side on the bed, or sofa, and on withdrawal of tlie stylet, a yard or so of small-sized elastic tubing, armed with a nozzle, is at once fitted into the canula. A natural syphon is thus formed, the fluid running into a vessel on tlie floor. No air can enter, and the elaborate precautions of 1 THE XEi:VOU.S SUBSTRATUM OF IXFLUKXZA. 101 IJowtlitcli are quite uncalled for. The \AeViVA gradual I >/ drains as the lung expands, and probably an hour or two will elap.se before the flow ceases. In these early tap|nngs, flakes of lynii)h, to obstruct the tube, are rarely or never met with. If the little ojjeration be done in this way, hurry, and any efforts to forcibly assist the flow being, of all things, avoided, it is ])erfectly free from danger, and the chances of recurrence or i)urulent degeneration are very small indeed. Perfect rest on the affected side sliould be enjoined afterwards, but I have not found strapping the chest do any particular good. Treated in this Avay, an uncomplicated case, in an otherwise healthy person, is usually perfectly well in four, or at the outside, five days, as I have proved in a vast number of cases. Of course, it must 1)6 borne in mind that we do not always see the patient from the first. If the effusion has existed some time, a different phase is entered on, with which this paper does not deal. A couple of cases particularly obtrude themselves on my memory as illustrati\'e of the advantages of such ti-eatment. Some years ago a well known acrol:)at and contortionist came to me. He had cauglit cold on board ship shortly before, and his left pleura was full of fluid, with heart di8{)]aceinent and great dyspncea. I sent him at once to his hotel and tapped him as described, keeping him in bed on his side for four days. He performed wonderful feats and antics in the evening of the fourth day, and during the week, when he left for a tour in the other colonies, expressing himself perfectly well. In six weeks he came to me again, having got chilled while waiting for the mail steamer on the pier at Adelaide. The 7'ight pleura was now distended with fluid. Same treatment, same result. I examined him before he left for America, and could discover no morbid signs. Another case was a young tradesman just married, most anxious to fulfil a building contract, but Tuial)Ie to work from dyspnoja and palpitation, caused by recent pleurisy M-ith effusion. Tapped on Friday, at work on INIonday. I examined him about a month afterwards, and found nothing abnormal in his chest, and g^nei'al health perfect. We all know v/hat would have happened if these cases had been treated medically and expectantly, or if tapping had been delayed till pyrexia had ceased — probably^ but not certainly, recovery in a fevj vxehs, with the risk of many untoward sequelae, and a depressed state of general health from confinement, low diet, lowering medicines, and worry at the loss of time and money. THE XERVOUS SUBSTRATUM OF INFLUENZA. By J. W. Springtiiorpe, M.A., M.D. Melb., M.R.C.P. Lond. Physiciau to thj Melbo.uno Hospital. Lecturer to tae University of Melbourne in Therapeutics, Dietetics and Hygiene. In the Australian Medical Journal for October 18S5 is an account, by the writer of the present paper, containing such information as was then ]>rocurable, upon the great epidemic of influenza which had visited Australasia during that year, and which was locally known amongst 102 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. our public as " fog fever." It was therein shown that influenza had reappeared, after many years of comparative absence, in a severe and widely epidemic form ; that, beginning in May, it reached its acme in August, prevailed over a large portion of Australasia, attacking a very large percentage of the population in Victoria at any rate, and apparently singling out those individuals who were daily much in the open air. A comparison of the features of the epidemic with the excellent description of that in 1847, given by Peacock, in " Quain's Dictionary of Medicine," showed how closely our epidemic followed the three main types therein difterentiated, viz., simple influenza, influenza with ])ulmonary complica- tions, and influenza with gastro-intestinal complications ; whilst the existence of an apparently new feature — the occurrence of cases witli well-marked cardiac symptoms — was commented upon, particulars of which are given in the record referred to. The present paper is in continuance of the investigation then originated, and aims at the explanation of the disease upon the basis of some specific virus depressing the pneumogastric and sym]iathetic nerves. The recurrence of the epidemic, the nature of external cause, and other points interesting from a differential diagnosis point of view, ai'e also incidentally touched upon as they have come into prominence, and been disclosed during this enquiry. 1. The Recurrence of the Epidemic. Observation has shown, that a disease with the same general characters as that already described, has returned each autumn and winter since 1885, and has been specially well marked during this late winter. In ray own practice, both hosj)ital and private, a very large proportion of my cases, from June until lately, have been distinctly influenzal in type. Anomalous cases, also, which seem explicable upon no other hypothesis than that which is hei"e advanced, have not been uncommon. 2. Causation. Little fresh light has been thrown upon the ccmsa causans. The late winter was as dry, as that of 1885 was wet and foggy — hence, the "fog" element, then insisted upon, is found, as elsewhere, to be non- essential. Variations of temperature, and of wind, liowever, have seemed very frequently to have had great influence in producing relajjses, if not in originating fresh cases. Again, from the mode of infection, the rapid onset, the wide range, the repeated relapses following atmospheric changes, the effect of change of air upon the course of disease, as well as from the practically constant presence of a naso-pharyngeal catarrh, it seems certain that tlie poison attacks the system thi'ough the medium of the air — though whether the matert'es viorbi be a specific microbe, or a peculiar atmospheric condition, remains problematic as ever. But, whichever it be, the incubation stage generally seems to have been extremely short. From some cases noted, in which i)rior infection seemed very unlikely, less than twenty-four hours elapsed. Throughout, relapses were the almost invariable rule. Lastly, the course of disease suggests the operation of a long-continued series of de])ressants. THE NERVOUS SUHSTJiATUM OF INFLUEXZA. 103 3. The Substratum Attacked. This paper is largely written to express the winter's conviction that the causa c((H.'ful examination has led the writer to regard as influenzal. The difi"erential diagnosis is discussed in some remarks in the Throat Section of the Congress in the discussion upon Diphtheria. The difference is maintained THE XEuvous sui!sti;atu.m of influenza. 105 to be essential, even though tlie virus of diphtheria seems to attack the same nerves in a soiuewliat .similar way. (fi) The gastro-intestinal form of influenza, confused with typhoid fever. — So far as the writer is aware, one outcome of this enquiry has been the discovery of a form of continued fever amongst ourselves, which is mistakable foi-, and has been mistaken for, typhoid fever, whilst really influenzal in origin. The difterential diagnosis between the two is entered into in the general discussion upon Typhoid Fever at the present Congress. (c) Another very important point elucidated has been the great number of cases of more or less acute phthisis, and even of acute tuberculosis, which have dated their origin to attacks of influenza, a result readily explicable, when we remember the extreme prostration and the pulmonic com]ilications of the disease, and the great influence which the pneumogastric exerts over the nutrition of the lungs and of the body generally. ((/) Lastly, the cardiac status produced by influenza in cases of heart weakness, is apparently a new point in symptomatology, and one of considerable importance. To the cases already adduced in the p)revious paper, others could be added. Only one extreme case, however, will be here given : — Mrs. C, jet. 2o, married, one healthy child ; father died of heart disease ; self and mother both hepatic ; patient always neurotic, often hysterical ; several times an^emic ; suffered from tyj)hoid fever with bronchitis thirteen years ago ; no syphilis, rheumatism, scarlet fever or chorea ; six years ago suffered from cardiac irregularity, the result, apparently, of dyspepsia and tea-drinking. Since marriage has worried very mucli. In lu85 had influenza, and a nasal catarrh each winter since. AVjout May last a fresh attack, with cardiac irregularity ; pulse uncountable, but no redema anywhere, though generally prostrate. Child born in August ; relapse soon after, with cardiac dyspnoea, swelling of feet, and all the appearance of serious heart disease ; twice seen by two medical men of standing, and told that she could not possibly live. When the writer saw her, seven weeks ago, she had orthopncea, oedema of feet and legs, paroxysms of Cheyne-Stokes respiration, with slight temi)erature, great weakness, anaemia, sweating, and marked p)ost-nasal catarrh. The lungs were sound, the pulse 160, and the ffrst sound accompanied by a bruit. After very careful examination, the opinion was given that anaemia, great excitement (patient, believing she was dying, had said " good-bye " to over twenty friends on the previous day), and influenza, would account for all her symptoms, and a less grave ])rognosis was gradually advanced. At present, with heart still beating i-apidly, and a bruit accompanying the ffrst sound, patient eats well, sleeps lying down, breathes naturally, takes gentle exercise daily without any oedema, is convalescing rapidly, and requires to follow only the ordinary cautions necessary in cases of vulnerable heart. [Six months have elapsed since the foregoing was written, and duiing that time diphtheria, influenza, and typhoid have been epidemic. This extended experience has remarkaljly verified the conclusions here advanced. The case mentioned above has required no treatment for four months.] 106 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. ON WANT OF PROPORTION IN THE SIGNS AND SYMPTOMS OF DISEASES OF THE HEART AND GREAT VESSELS. By James Jamieson, M.D. Lecturer on Medicine at the Melbourne University, and Physician to the Alfred Hospital. It is an oft-repeated, and perhaps ratlier trite observation, that in the knowledge, and even the ability to make good use of the modern i-efinements in j^hysical diagnosis, there may not be an unmixed gain. There is certainly a tendency — pardonable perhaps, but still eironeous • — to lay undue stress on them, to the extent of reckoning that when we have inspected and ])alpated, percussed and auscultated the chest, we have done almost all that is I'eally essential for diagnosis, and for the treatment based on it. Most of us, perhaps, need to be reminded of the truths so strongly insisted on by Dr. Stokes, in the preface to his work on " Diseases of the Chest " : — " It cannot be too often repeated that physical signs only reveal mechanical conditions, which may proceed from the most ditferent causes ; and that the latter are to be determined by a process of reasoning on their connection and succession, on their relation to time, and their association with si/mptoms. It is in this that the medical mind is seen. Without this power, I have no hesitation in saying that it would be safer to wholly neglect the physical signs, and to trust in ))ractice to symptoms alone." Even with all our improve- ments in physical diagnosis — and tliese have been considerable, even since Dr. Stokes published his great work — this is still good doctrine, though it may be good doctrine pushed to its extreme consequences. For, doubtless, there may also be error in allowing the conclusions based on symptoms to override those derived from a consideration of physical signs. It is with the view of illustrating and emphasising tlie truth, so well stated in the iirst part of the quotation just given, that I have thought it worth narrating the following cases, which have come under my observation at the Alfred Hospital. They are intended to show the benefit to be derived from using all available he]j)s in diagnosis ; and to indicate, further, how great is the difficulty which may be experienced in arriving at correct conclusions about tlie extent and severity of organic disease of the heart and great vessels, and how one may be led astray to regard that severity as greater or less tlian it really is. The first case was that of a man, T. D., a sailor, aged oO, admitted to the Alfred Hospital on 16th August, 1888. He stated that, till a month before admission, he had been well, and able to do a full day's work at full current wages. When working in water, he caught cold, getting a dry cough, and suffering from dyspnoea, with some swelling of the belly. A week after, the legs began to swell, though this swelling for a time disappeared, and the dyspncsa was not marked, when lie had been lying down. Two or tla'ee times he coughed up a little bright red frothy blood. Had scurvy eleven years before, but had never suffered from rheumatism. All his peojjle had been healthy, as he had been himself. WANT OP PUOI'ORTION IN SYMPTOMS OF JIKART DISEASES. 107 On iulmission, tlie legs and belly were much swollen, and there vvas slight cedema of the chest-wall. He had a markedly cyanosed look about the face, and he suffered so much from dyspnciea, that he was unable to lie down. The superficial veins of the neck were distended, the ])rouunence being most marked on the right side. He had a troublesome short cough, but no expectoration. Examination of the lungs revealed nothing more than harsh breath sounds anteriorly ; but at both bases, ])OsteriorIy, there was slight dulness with crej)itation, but no increase of vocal resonance. The examination of the heart showed that the apex beat was displaced downward, and to the left ; and a double blowing sound was heard there, and was transmitted to the left. Over the tricuspid area, there was heard a loud systolic murmur ; and the second pulmonary sound was accentuated, and had quite a ringing character. The aortic sounds were not altered in character. The pulse was 100, regular, but compressible. It appeared, therefore, that we had to do with a case of mitral disease, the signs being those of obstruction and incompetence combined. It was further evident, from the sounds heard at the right apex and base, that there was tricuspid incompetence ; this being also made plain by the swollen condition of the veins of the neck, and the marked cyanosis. The treatment consisted in the use of the hosjiital stimulating mixture, with m. xv. of tincture of digitalis. Under this he improved for a time ; but when he became worse again, both Tinct. of strophanthus and this same mixture were tried, without any appreciable good effect. On the 20th, he was found to be in some respects much improved, the dropsical symptoms having disai)peared, but he was not yet able to lie down on account of the dyspnoea, and the veins of the neck were still distended. The murmui's described had not altered. Pulse tracings were taken on this day for the first time, with Dudgeon's sphygmograph, with the condition here shown : — Perhaps this did not show more than that the heart was supplying a small amount of blood to the arteries at each systole ; but, at least, it seemed to give some confirmation of the supposed state of things at the mitral orifice. From this time there was continuous improvement in the general condition, the breathing becoming much easier, and cj^anosis to a great extent disappearing. There was evidence of improvement, also, in the following pulse tracing, taken on the 28th : — fW k iV. (W^ fv /V ^v /V k k A But on the 30th, the whole as])ect of the case was found to have changed for the worse. He was taken with increased difKculty of breathing ; the cyanotic condition of the face again became fully apparent, and he was seized with fits of coughing, when he spat up blood, not much mixed with mucus. From this time, the course was steadily downward ; the cough with bloody expectoration continuing, and pain LIBRARY OF THE LQ5 ANGLES COUNTY MEDICAL ASSOCIATION 634 SOUTH WE3TLAKF AWF. 108 INTKRCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. in the chest, with pleuritic rubbing, helping to make it evident that there was pulmonaiy embolism, with infarct formation, going on. The breathing for some days had the Cheyne-Stokes character, and this enabled us to make an interesting observation. Pain was complained of on the left side, at the base of the heart ; and, when i-espiration was deep, there was a distinct friction sound, synchronous with the chest movements ; but when respiration almost ceased for a short period, the rubbing sound was synchronous with the cardiac contractions. Deatii occurred on September 12th. On post-mortem examination, both sides of the heart contained clots, which in the auricles had in part an ante-mortem character. The left ventricle was dilated and hypertrophied, the only distinctly morbid condition at the mitral orifice being, that one of the valves was slightly shortened, so that closure was not perfect. There was no constriction of the opening, and careful examination revealed nothing more than a slight roughness on the surface of the valves, which, but for the fact of a murmur having been lieard, accompanying the auricular systole, might readily have been overlooked. The right ventricle was dilated, and the tricuspid opening rather enlarged. There was an increase in th.e amount of pericardial fluid, but no roughness of the surfaces. There was, however, fibrinous deposit, causing roughness of the pleural surfaces at the base of the heart, its situation accoimting for the fact that the heart was capable, by its movement, of causing the friction sound, synchronous with its contractions and easily heard when respiration tempoi-arily ceased. Both lungs contained several infarcts, and both showed some consolidation at the bases ; the kidneys were slightly granular ; the liver was congested, and showed indications of the nutmeg condition. This case had several points of interest about it. It was not easily apparent, how such severe cardiac S3-mptorns should have come about so suddenly in a man previously healtJiy ; and it can hai'dly be said that the post-mortem examination helped much toward a clearer explanation. Till careful investigation was made, it did not appear that there was any disease of the mitral valves at all ; and there was certainly nothing in their state, incompatible with the continuance of life for some years, with at least fair health. Up to August 29th, indeed, he seemed to 1)6 in a fair way of recovery, the supervention of severe symptoms then being due to the pulmonaiy embolism. It might even be suspected that the strengthened action of the heax't, which led to such general imjn-ovement, had the counterbalancing disadvantage, that more vigorous contraction favoured the detachment of clots, which had been deposited in the right heai't, at the time when it was much dilated and weak. It may safely be said that the mode of production of such severe heart symptoms was unusual. In some chronic lung conditions, and notably in emphysema, it is well known that the right ventricle becomes hypertrophied, with consecutive dilatation and incompetence, followed by venous stagnation and dropsy. Could the same state of things have come about here quickly, as the result of some acute obstruction to the circulation through the lungs'? If we assume the occurrence of tricuspid incompetence, with consequent stagnation in the systemic venous system, we can understand further that the increased work thrown on the left ventricle, by this stagnation working backwaixl into the arteries, caiised the slight mitral aftection to acquire importance. In this way the WANT OF PllOPORTION IN SYMPTOMS OF HEART DISEASES. 109 vicious circle would be luiule complete, though in an order the reverse of that most frequently observed. The second case was, in some respects, the counterpart of that just related. The patient, S.D., a butcher, aged 38, was admitted to the hospital on 18th July, 1888, having previously attended as an out-patient. He stated that he had had an attack of rheumatism six years previously, and liad suffered from slight shortness of breathino- ever after. On the whole, he had enjoyed good health, and followed his occupation till November 1887, when, after lifting carcases of shf,'ep, he felt an aching pain in the left side. Since that time, he had suffered more or less from pain of a throbbing or aching character. He was not aware of having strained himself, and certainly had no symi^toms of an acute nature. For the previous three months he had been Avorse, the pain extending to the left groin and the loin, and being sutiicient to make his sleep broken. There had never been swelling of the feet, or any distinct pulmonary symptoms. On examination, the first thing remarked was the distinctness of the apex beat, seen and felt in the fourth or fifth intercostal space, according as the chest was in inspiration or expiration. As he lay in bed, his breathing was quiet and regular, and no abnormality of the lungs could be detected. Auscultation revealed a slight systolic sound at the apex, not communicated to the left. There was a double bruit, heard loudest to the right of the sternixm, over the aortic orifice, but transmitted rather widely to the base of the heart, toward the right clavicle, and down the whole length of the sternum. The diastolic murmur was very loud and long drawn. In the epigastrium, and as far down as the umbilicus, there was a faint systolic sound heard. On examining the chest posteriorly, there was found a spot on the left side, between the eleventh and twelfth ribs, where there was tenderness on })ressure, and distinct heaving pulsation. At the seat of pulsation, there was heard a faint bruit, about equal in intensity, and similar in character, to that noticed just above the umbilicus. There was no abnormal pulsation to be felt in the corresponding part of the lumbar region anteriorly, though it liad been distinctly noticed in that situation when he was first seen in the out-patient room Ijy Dr. Maudsley. He liad then, and previously, complained of pain and throbbing, extending from the margin of the ribs to the groin, on the left side. After admission, not only had this pulsation entirely disappeared, but it was easy to define the abdominal aorta, to all appearance normal on palpation, along the greater part of its course. The supi)osition was, that he had double aortic mischief, the character and localisation of tlie murmurs jiointing distinctly to that defect, but it was not at all clear what was the cause of pulsation in the lumbar region. 8j)hygmographic tracings were taken, for the purpose of getting whatever light might thus be obtainable, and they were found to be tliQ same on both sides. The tracing shown, thougli not that of a typically normal i)ulse, certainly has not the special characteristics either of aortic stenosis or regui'gitation. It has not the sloping rise and rounded top of the first, 110 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. and just as little does it exhibit the sudden and deep fall of the other. In so far, therefore, as the sphygmographic indication went, it was only in taking away any marked significance from the murmurs heard over the aortic area. Some roughness there probably Avas at the aortic entrance, causing the systolic murmur, and the loud and long diastolic bruit could hardly be accounted for on any other supposition than that of reflux from the aorta into the ventricle. But if such regurgitation tliere was, it certainly must have been small in amount, and going on through a very small opening. That the disturbance of the blood current in either direction, in the neighbourhood of the heart, was slight, was also shown by the fact that the man steadily improved under the influence of rest, losing the pain he first complained of, and never experiencing difficulty of breathing ; in fact, he expres.sed his ability and willingness to go to work again. There was still little appreciable change in the murmurs described, or in the pulsation in the loin. On the 7th August however, there was slight pulsation noticed for the first time, in the second intercostal space, close to the right sternal border. This became more marked, and was easily distinguished on the ISth, just before he was discharged at his own request, promising to return and report himself. This case was a very interesting one, the physical signs being so obtrusive, and the general symptoms comparatively slight. The most probable supposition, perhaps, is that there had been effusion of blood into the sheath of the descending aorta, without much, if any, injury to the proper aortic wall, so that recovery by absorption was possible. But, independently of this assumed accidental condition, it seems certain that there existed dilatation of the aorta, which was undergoing slow but progressive development, and was making itself more apparent at last, by ](ulsation to the right of the sternum. After this was written, the man presented himself again for examination on 20th December, four months after his discharge. He had been losing weight, biit had continued at work, and declined re-admission. The murmurs heai-d about the aortic area wei'e not much altered, but the ]>ulsation on the right side was more distinct, being easily seen and felt in the second intercostal space, and less so in the third, about an inch and a half from the sternum. The pulsation in the left loin was just the same, but the blowing sound seemed to be rather louder, and also heard further up along the left side of the spine. Pulse tracings were again taken, right and left radials being found similar. Those here given are from the left radial, the first taken in the recumbent, the second in the sitting posture, and it cannot be said that they give any assistance in diagnosing the exact nature of the severe condition undoubtedly present. I A third case may be shortly narrated, in which, with very marked implication of the heart and great vessels, there was relatively but a WAXT OF PHOPOKTIOX tX SYMPTOMS OF HEAHT DISKASKS. Ill sljglit ainouiit of general di.sturbance. The patient, F. G., aged 54, by occupation a hodcarrier, was admitted to the hospital on 8tli October, 1888. He stated that he had always been well, and tit for hard work, till six months previously, when, having got drunk, he lay in wet clothes all night. Soon after, lie was seized with a severe oough, which was harsh in character, though not attended with pain. His voice also became hoarse, so that for a time he could scarcely make himself under- stood. Gradually, his breathing became rather difticult on exertion, though it was all right so long as he was quiet. He had never been troubled with giddiness, and for some time he had slept well. Just al)0ut the time of admission, he had begun to feel shooting pains in the left shoulder, and a feeling of weight in the epigastrium. A week previous to admission, he spat up a small quantity of blood. On admission, it was noticed that his voice was harsh in tone, and that he had a loud brassy cough ; but nothing abnoi'mal was discovered about the vocal cords. Inspection of the chest revealed very marked deviations from the normal condition. The upper part of the left side was covered with large veins, some crossing the sternum to the right. There was also a swollen condition of the veins of the left upper arm. The supra-clavicular space was also more filled out on the left than on the right. As he lay in bed, there was no sign of cardiac impulse to be seen or felt in the usual situation, but there was marked pulsation, resembling a good deal that of the cardiac apex, to be seen and felt in the second intercostal space on the light side, about two inches from the sternum. To the touch, it was a sharp stroke, re-duplicated in character. "When he stood up, a centre of pulsation could be made out on the left side, behind the cartilages of the ribs, on a level with the tip of the ensiform cartilage ; but even then there was no distinct apex-beat to be felt am^vhere. On percussion, there was dulness on the right side, down to the level of the third rib, and on the left to the upper border of the fourth rib. The cardiac sounds could only be faintly heard on the left side when he lay quiet, but became louder and more distinct when he stood it}» ; and were heard best low down, behind the combined costal cartilages. They were heard most loudly over the seat of pulsation on the right side, when he was lying, and even when he stood up, they were at least as loud as over what corresponded with the cardiac area. In neither situation were the sounds accompanied or displaced by a bruit. The only thing that could be called a murmur was heard, and that only occasionally and faintly, behind the cartilage of the sixth i-ib on the right side. Posteriorly, there was nothing abnormal discovered on the right side, except unusual distinctness of the heart sounds ; but on the left, there was dulness on percussion, down almost to the angle of the scapula, and there, as in the infra-clavicular region in front, the breath and voice-sounds were faint. The case had very striking features, therefore. There was evidently a tumour, occupying or compressing the upper lobe of the left lung, and pressing on the left subclavian vein. The heart was considerably disj)laced, and at first, indeed, it almost seemed as if it had in some way got jnished completely up l)eneath the right clavicle, both pulsation and cardiac sounds being so distinct there. That idea could not be held, however, for there was no unusual dulness behind the middle of the sternum, and it was impossible to understand how any tuuiour, in the upper part of the left thorax, could have pushed 112 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA, the lieai't up beneath the riglit clavicle with its apex still downwards. It was also made aj^parent, in time, that the heart had been actually pushed down, so that its pulsations were hidden behind the conjoined cartilages. It had further to be assumed that the pulsation on the right side was caused by the aorta, tliough it was difficult to account for its position, so far to the right and high up, when the heart w^as at the same time driven down. Of course an aneurismal dilatation of the ascending aorta might extend far to the right ; but the pulsation was very distinct and shai']), and not at all a distensile heave. And besides, there was not the dulness on percussion behind the sternum, which might have been expected in the case of a large aneurism of the tir.st part of the aorta ; and there was no blowing sound to be heard at or near the seat of jjulsation. S})hygmogra[)hic tracings of both radial pulses were taken, and were found to be similar in character ; and as will be seen, not much help was got from this source, the curves not differing materially from those commonly enough got in healthy persons. N K N In spite, too, of the marked local signs, the man was not long in the hos])ital before he began to say that he had no pain ; that he ate and slept well ; and was fit to undertake a light job, which he knew he could get. He certainly exhibited very little in the way of distress, or any general illness, and was at last allowed to go out, with the request that he would report himself in a short time, and at least return if he became worse. It may be regarded as certain that there was some dilatation of tlie aorta in its first part, though tlie pulsation was a distinct double beat, and some of the most characteristic signs of aneurism were lacking. This was confirmed by the fact that, a few days before he was discharged, it was noticed that there was a little bulging of the second intercostal space, and of the third rib, even though the pulsation remained the same in character, and no 1)ruit could be heard at its seat. The only attempt at active treatment consisted in the introduction of an ex])loring needle at tlie second left intercostal space, in the hope that the tumour might be of hydatid nature. The needle was introduced to the depth of two inches, entering easily, l)ut no fluid was got, not even blood. The result Avas, therefore, purely negative. A CASE OF CEREBELLAR DISEASE. 113 A CASE OF CEREBELLAR DISEASE, IN WHICH AN EXPLORATORY TREPHINING AND REMOVAL OF DISEASED BRxVIN SUBSTANCE WAS FOLLOWED BY GOOD RESULTS. By Hexhv Maudsley, M.D. The .surgical treatment of intracranial tumour.s, and other conditions of the brain which are diagnosed, not by any deformity of the skull, nor by any history of injury, but by the symptoms general and focal they give rise to, being still in its infancy, it is our duty to report all such cases, wliether successful or not. Only in that way is progress likely to be made, and it is to be borne in mind that the reports of unsuccessful as well as successful cases are likely to advance our knowledge. This must be my apology for reading before such an assembly an account of a single case. On January 9th, 1888, I saw, with Dr. Davenport, H. C, a gentleman '^0 years of age. He gave us the following history : — He had never been out of Australia, had travelled much in the bush, and had enjoyed good health until the onset of the present illness. There was no history of syphilis, of head injury, or of disease of the middle ear. He had been temperate in all things. There was no liLstory of tvxbercle, of cancer, or of tumour of any kind in his family. In September 1886 (sixteen months before I saw him), he began to suffer from headache. The headache was severe, more or less constant, l)ut paroxysmally wor.se. It was referred to occipital region, and radiated towards the vertex. Since that date his headache has continued, occasionally a week elapsing without pain ; latterly, the paroxysmal pain has become worse. In December 1886 (three months after the onset), he began to sutler from attacks of vomiting, independent of any errors of diet. The attacks would last one to three days, and rarely a week elap,sed without an attack. During the attacks, the pain in the head was " agonising." These attacks have not diminished in frequency or sevei'ity, liut, on the contrary, have inci'eased. In July 1887, he began to suff'er from giddiness, and his gait liecame affected. He .staggered like a drunken man, and had a tendeiicy to fall forwards and to the left. In Augu.st 1887, dimness of vision came on fir.st in the left eye, and in the course of a month he l>ecame completely blind, Ijeing unable to see the Ijrightest light. Before the onset of blindness, he would occasionally see double. Deafness in the left ear came on aljout the same time, and seemed to have a gradual onset. Since September 1887, lie has had some difficulty in walking, independent of his blindness, the left arm and leg being awkward in their movements. Since the same date thei'e has been asymmetry of the face. There is no history of convulsions, or of loss of consciousneiss. On January 9th, his condition was as follows : — He is a tall, stout man, complaining of lieadache, vomiting, blindness, and deafness on the left side. On testing his cranial nerves, we tind a complete I 114 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. absence of the sense of smell, complete blindness, and deafness on the left side. There is slight paresis in all the muscles (the upper and lower groups), supplied by the facial nerve. There is no ati'ection of the ocular muscles or of those of mastication. The pupils are unequal, the right widely dilated, the left of medium size. Neitlier pupil reacts to light ; the left reacts in accommodation, the right is sluggish. There is no nystagmus. Examination of the fundus oculi reveals a white hlled-in disc, the arteries ai'e small, and obscured by white inilammatoiy deposits. There are numerous wliite patches around the margin, suggestive of old hfemon'hages. The apj)earances are indicative of white atrophy, conseciitive to neuritis, and the blindness is no doubt due to this cause. The non-reaction of the pupils to light, their reaction on convergence of tlie eyeballs, is further evidence of this atrophy being the cause of the blindness. There is no actual motor paralysis of the limbs, but the movements of the left liand arm and leg are more awkward than natural. When supported by two persons, he has a distinct tendency to fall to the left. There is no typical hemiplegic gait. He complains of some numbness and tingling in both hands, but there is no loss of sensibility to touch, pain, or temperature. The superficial reflexes are normal. With regard to the deep reflexes, the knee-jerk is obtained with difliculty on the right side ; on the left, its presence is doubtful. Ankle clonus is not present on either side. His bladder and rectal reflexes are normal, and his sexual condition is normal. He gutters from constipation. Examination of the skull reveals nothing abnormal. His heart, lungs, liver and spleen are normal. There is no sign of hydatid, no evidence of syphilis, old or recent, and no evidence of ear mischief. Tlie urine is free fx'om sugar or albumen. Such being the condition of the patient, witli such a previous history, there was very little doubt that he was suffering from organic brain disease, and little more doubt that the disease was either an intracranial tumour in its widest sense, or an abscess of the brain. The exact nature of the tumour, its size, and its position, were not so clear. With regard to the position, the slow onset of the disease, the genei'al symptoms having existed a year before any focal symptoms appeared, the character of his gait, the probable simultaneous occurrence of left facial paresis witli deafness on the left side, tlie diminution of the knee- jerk on the right side, and its doubtful presence on the left, seemed to point distinctly to some lesion involving tlie left auditory and left facial, where these are in contiguity, and to some attection of the left lobe of the cerebellum. An absence of any distinct paralysis, motor or sensory ; an absence of any convulsions, the position of the headache, and the severity of the vomiting, also favoured the view of the lesion being in the cerebellum. Deafness occurring alone, is of little value in localising a lesion, for liajmorrhage into the nerve or its nucleus, or into the end organ, is not unfrequently a cause of sudden deafness; but deafness on tlie same side as a facial palsy, and not dependent on disease of the middle ear, points strongly to one lesion involving both nerves near their entrance into the internal auditory foi'amen. That the lesion causing the deafness in the left ear, was not in the right temporo-sphenoidal lobe, in the pcrcepti^'e centre for hearing, may A CASK OF CKJtKBELLAK DISKASK. 115 be dismissed, as in lesion of one temporo-sphenoidtd lobe tlie deafness is only temporary, the same being the case in experimental lesions in the monkey. From these considerations, one lesion in the left lobe of tlie cere))ellum, about the amygdala, causing pressure on the neighbouring left facial and left auditory, seemed highly probable. With regard to the pathological diagnosis, abscess may be dismissed .at once, as thei'e was no ear mischief, and never had been any, and no liistory of a blow, and there was an absence of fever. Syphilis and tubercle may he dismissed, as he had been treated by mercury and iodide of potassium some months before, by Dr. Springthorpe. There was no evidence of tubercle elsewhere in the body, and no family histoiy. The diagnosis seemed to lie between hydatid and a sarcoma or glioma of the cerebellum, or some tumour growing from the temporal bone, about the internal auditoiy foramen, and pressing on the cerebelknu. Against its being a hydatid, was the absence of any signs of hydatids in other organs, and the site (cei-ebellum or base of the skull) is not one favoured Ijy hydatids, the majority occurring within the cranium being in the cerebral hemispheres. Dr. Thomas' valuable paper, at the last meeting of the Congress, showed that out of 97 cases of intra-cranial liydatids, in 1 1 there were hydatids elsewhere, chiefly (5 of them) in the liver, and of these 97, only i were in the cerebellum, so tliat the chances of tliis being a hydatid were not very great. The pathological diagnosis, then, remained doubtful. The pati(?nt and friends, having heard of tlie successful cases of brain surgery, were in liopes that something might be done. However, when they were told that any operation would he an exploratory one — that the result of it was very doubtful ; that the two cases of attempts to remove a cerebellar tumour had ended fatally ; that if the tumour were safely removed his eyesight would not return — the friends were vmwilling to have any operation. During the next thi'ee months, the patient made no improvement. His headache became worse, and his attacks of vomiting were more frequent, the patient and his friends were now anxious that an exploratory operation should be pei-formed. On April 8th, I saw the patient with Mr. FitzGerald. The symptoms were the same as in January, except that he had gradually become deaf on the right side. Mr. FitzGerald agreed with me, that there was probably a tumour in the left lobe of the cerebellum, and that consecutive to tliis was a distension of the ventricles, from inflammatory thickening of the meninges about the base. He considered an exploratory operation quite justifl able. The deafness on the right side somewhat complicated the case ; upon tlie whole, I was of opinion that it was caused Ijy neui'itis of the right auditory nerve. Dr. Springthorpe, who had seen the patient before any localising symptoms appeared, saw liim, and was present at the operation. He was of opinion that there might be a tumour in the left lobe of the cerebellum. Dr. Davenport, who had watclied the case for .some time, concurred in the diagnosis. On April 20th, the head having been shaved and the scalp waslied with jether, and kept in a carbolic towel for twenty-four Jiours, Mr. FitzGerald made an incision from the occipital protubei'ance outwards along the left superior curved line, and another downwards from a point midway lietween mastoid and the protuberance at right angles to 1 2 IIG INTERCOLOXIAL MEDICAL CONCiRESS OF AUSTliALASIA. the tirst, and reflected the soft parts. He then trephined below the line of the lateral sinus. The bone was thin ; on removal, the dura mater bulged above the level of the opening, and presented a cyst-like appearance. On inti-oducing a needle, no fluid escaped. The dura mater was incised. The cerebellum bulged out, and was so soft that a quantity ran away. There was no pulsation. A needle introduced in a direction towards the petrous portion of the temporal, brought away jio fluid. Mv. FitzGerald introduced his flnger, and found the brain substixnce Aery soft, and came on what seemed to him to be a solid nodular growth fixed to temporal bone, under the tent in proximity to the temporal bone. The brain substance was decidedly softer than normal cerebellar substance. It was decided not to proceed further. Mr. Fitzgerald then, having seen advantage in a previous case from tapping the ventricles in a case of hydrocephalus, trephined over the temporo- occipital region of the skull with a small trephine, and passed a small hollow needle in the direction of the venti'icle. No fluid escaped. The bone was at once replaced, and the wound stitched. The flaps over the cerebellar wound were stitched, and a drainage tube introduced. The wounds Avere dressed Avith salicylic wool. Dr. DaAenport gaA-e the chloroform, after liaA ing administered ^ grain of morphia hypodermically. There Avas Aery little l)leeding from the brain substance. The patient did not sufler so much from shock ; his temperature Avas normal ; liis pulse aljout 100. The pupils contracted under the influence of morphia. The trephine Avound OA'er the Aault healed by flrst intention, the bone adhering at once. Within three Aveeks, the occipital Avound was reduced to a superficial granulating sore. The patient conA'alesced rapidly. AMien he Avoke up from the chloroform, his old pain had left him. C)n the third or fourth day, he had noises in the right ear, and by the seventh he could hear sounds ; by the fourteenth, he could hear Avords spoken sloAvly in a loud Aoice ; and l)y the end of the month, he could listen to his nurse reading the morning paper. He had subjecti^■e flashes of light, Ijut he Avas quite blind. Since the operation, there has been no return of the pain, no attack of A'omiting, and his gait is now that of a blind man, there being no tendency to fall to the right. He is deaf on the left side, partially on the right, and he is quite blind, the optic discs being in a condition of Avliite atrophy. He eats and sleeps Mell, but at times he is much depressed, OAving to his blindness. What the exact lesion was, remains doubtful. Was the left lobe of the cerebellum the seat of a soft glioma? Or is thei'e a tumour in connection Avith the temporal bone or the tent, which has ceased to groAv since tlie operation ? The extreme Inilging of tlie cerebellum into the opening, and the softened condition of the cerel)ellar tissue, seem to make it probable that tlie left lolje of the cerebellum was the seat of a soft glioma. Unfortunately, none of the brain substance Avliich came away Avas examined undei- tlie microscope. Note on July 12, 1889. — The patient still continues in good health. There has been no return of the lieadache or of the attacks of Aomiting. ][e is deaf on the left side, and his sense of hearing is deficient on the A CASE OF IXJUKY TO 'niK FKOXTAL IJECilON OP THE BRAIX. 117 riglit; but he cun comei'se with liis fiiends, and can hear wlien spoken to. He is completely blind. Evidently there is no recurrence of any growtli, so that tlie probability of there having been a glioma in the cerebellum is not great. CEREBELLAR DISEASE. Dr. Verco related a case lie has seen in consultation, in which there were ditiiise, distant symptoms pointing to possible existence of cerebellar disease, but not sufficient to justify operative interference. A short time afterwards the patient came into the hospital, and died in about two days with typhoid symptoms. On autopsy, there was found a cyst on the under surface of the cerebellum, about its centre, but hollowing out one lobe. It apparently originated in the pia-mater, had no limiting membrane, and no hydatid cyst. The substance of the cerebellum was somewhat softened. In this case, had operation been undertaken, the cyst might have easily been opened, and recovery resulted. This suggests that Dr. INIaudsley's case might have been such a sub-cerebellar cyst, with some degenerative softening of the left cerebellar lobe. On opei'ation, the lobe might have presented, and the linger liave been passed into and through tlie softened organ, and into the simple cyst, the contents of which might have been allowed to flow out without notice. Gliomata are, as a rule, soft, non-encapsuled infiltrating growths, and it is somewhat difficult to understand so complete a removal of them by simple breaking down with the linger, as to prevent recurrence. A CASE OF INJURY TO THE FROXTAL REGION OF THE BRAIN. By D. CoLQUHOux, M.D. Lond., M.R.C.P. Lond. On August 5th, 1S87, I was called to see Mr. H. A. B., aged 24: years, who was suflering from violent epileptic tits. When I saw him he was unconscious, and breathing heavily, but there were no signs of paralysis. He had for the next four days very few periods of remission, fit following lit in ra2:)id succession. On the 7th of August, tliere was a brief interval of consciousness, lasting for an hour or so, in which he recognised those about him. This was followed by severe fits. On the 8th August, he became comatose between the fits, urine and tWces escaped into the bed, cystitis set in, and on 9th August he died. The fits came on in a manner common to many cases of epilepsy. He gave a sudden cry, the head became extended, and violent general convulsions came on. Tlie right hand and arm, however, seemed to me 118 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. to have little intrinsic movement, but to be moved mainly by the general tremor of the trunk. I made an examination of the body next day. In physical structure there was nothing noteworthy. The body was small, but normal. In the centre of the forehead, near the anterior limit of the hair, an elevation about as big as a horse bean covdd be felt. It was smooth and hai'd, and felt like callus. On removing the scalp, this was found to be a bony growth at the seat of an old fracture. In the right temple there was an opening into the skull, covered in by dense fibrous tissue. On removing the calvarium, tliis aperture was seen to be the beginning of an old fracture, which led to the centre of the frontal bone. There, corresponding to the external boss, was a flattened and ragged pistol bullet, embedded firmly in the inner table. The brain and dura mater were here so firmly attached to the skull, that they had to be removed in part with the calvarium. The veins on the siirface of the brain were distended with blood, and the lateral ventricles contained excess of fluid. Dr. Scott, Professor of Anatomy at Otago University, who kindly examined the brain, gave the following account of it : — " The bullet seems to have first come in contact with the brain at the posterior end of the lowest horizontal frontal convolution of the right side. The entire length of this convolution was degenerated, and adherent to the skull ; indeed, came away with the skull-cap when it wjis removed. The external convolution, on the orbital face of the frontal lobe, was also in the same condition. The anterior half of the middle horizontal convolution, and the anteiior third of the superior, were like- wise destroyed and adherent. The bullet finally lodged against the superior frontal convolution of the left side, which was indented and narrowed." As I had been informed that the wound Avas originally inflicted in Exeter, I wrote to the hospital there, and Dr. A. G. Blomfield, Physician to the Exeter Dispensary, very kindly obtained the following- details for me. He wrote as follows : — " The case was not under treatment in the Exeter Hospital, but at the Torbay. Dr. Braufoot, who was House Surgeon there at the time, writes me as follows : — ' I recollect very well the case of poor Mr. B., and some interesting points were published in the British Medical Journal, probably in August 1883. The lad was bi'ought in from Daddy Hole Plain with a bullet wound in the right temple. The bullet had evidently impinged near the mid-line on the inner surface, smashing the cranial bones ; and there was a discussion at the time as to the bullet being felt beneath the integument in one of the crevices. The lad was stupid and dazed on admission, and somewhat collapsed, but in three or four hours answered queries as to name, address and profession of his father, and a few details about the deed, and his reasons for the last. Subsequently, he had pyrexia and synq_)toms of inllannnatory reaction in the cranium, and Ijecame gradually more and more stupid, but in ten days' time all fever subsided, his mental faculties began to re-awaken, and he made an uninterrupted recovery. He was soon tired by attention to books, or reading for a long time, and occasionally became excited and emotional. When admitted, no local palsy of any kind was discovered, but subsetjuently he lost power in the left hand and arm, and the lower part of the left side of the face was paralysed as far as volitional A CASE OF INJURY TO THE FRONTAL REGION OF THE BRAIN. 119 nioveiuent went, but for ordinary purposes of expression, of motion, and eating, his facial and mouth muscles seemed to act normally. As far as I recollect, this weakness of the side of the face and limb developed subsequently, or coincidently with the iniiammatory reaction of the wound in the head. When seen at the Exeter Assize, though his look was unsteady and wild, and he gave one the idea of want of steady attention, yet he talked of the future (viz., that he was going to study medicine in Edinburgh) quite rationally, and he expressed his gratitude for what had been done. There was no other paralysis but the one mentioned.'" Dr. Blomfield adds that he had been unable to discover if the patient had been epileptic before the attempt to commit suicide, or his mental condition before that. I have not been able to find the case rej^orted in the Journal, so that I can only speak of his mental state as I had been able to observe it since he came to New Zealand. He called on me soon after he arrived in New Zealand, about three years ago. He had made a proposal for life assurance, and told me, in the course of my inquiries, that he had tried to commit suicide, and that a pistol bullet was lying somewhere in his brain. He also informed me that he was subject to attacks of epilepsy, but I cannot recollect if these attacks had come on before the attempted suicide, or afterwards. I advised him not to go on with the proposal for insuring I lis life, and he immediately agreed, asking me not to mention what he liad told me, as he was anxious that his antecedents should not be known in the colony. Afterwards, I found he had made similar confidences to nearly all his acquaintances. I saw him occasionally during the next three years, but never professionally until during his last illness, but he spoke freely about his attacks. Fits occurred seldom, 1)ut when they came on they were very severe. On one occasion I met him in the street, and he told me " he had, he thought, beaten the record, having had about 300 tits in two days." He fell into the hands of an American advertising quack early in 1887, who promised to cure him, and received a relatively high fee from him. A somewhat long interval of freedom from fits was followed by the last fatal attack. He had spent a year or so in studying medicine at Edinburgh, and was intelligently intei'ested in medical matters. A few weeks before his death, he spoke to my surgical colleague, Dr. Brown, about the advisability of submitting to the operation of trephining, for the removal of the bullet. Dr. Brown approved of the operation, but Mr. B. did not again pi-esent himself. In business he was not very successful. He entered one of the banks as a junior clerk, and remained there for a few months. He was apparently not tit for sustained work, and was very forgetful. He tried several kinds of work, and finally bought a small business, in which he lost the little capital he had possessed at starting. He was not without shrewdness in money matters, but was easily moved, by anyone who was in his company, to do extravagant and foolish things. His tastes were in many ways elevated and refined. He was fond of music, poetry and pictures. He was, on the other hand, intensely erotic, and quite unal)le to restrain his passions. At one time he was weeping and praying about his sins, and attending a Ritualist Church, and in a few weeks he had become a sceptic, and was cynical about human vii-tue. He was lialile to gusts of fury, often set up by mere trifles. These would pass off as quickly 120 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. as tliey had come on, and he would then apologise humljly for what lie had said or done. He was, on the wlioie, kindly and well disposed. He was emphatically a creature of impulse, but his impulse, as a rule, was towards good ; but if it happened to be towards evil, he had no power to check it by any restraint of will. The case is mainly interesting as a contribution towards the localisation of the cerebral functions. In connection with it, I may cite a case I'eported by Dr. S. K. Towle, and quoted in the fifth volume of " Pepper's System of Medicine." Dr. Towle says: — "The man had been a lieutenant in a volunteer regiment, and I gave him rather more privileges (in the Soldier's Home at Milwaukee) on that account ; but after a time I found that he was more nearly an example of total depravity than I had ever seen. There was no truth in him, and he was intelligent enough to make his lies often seem plausible to me, as well as to others. By his wi'iting and talking, and conduct generally, he kept the patients and their friends in a ferment, and gave me more trouble than the whole hospital besides. He had a small scar about the middle of the forehead, which he said was due to a slight flesh wound from a glancing ball in battle. While he was under my care, an older brother came to see him, and he told me that, up to the time his brother (my patient) entered the army, he was almost a model young man — amiable and affectionate, the pet of the whole family and intimate friends ; but, said he, ever since he came back he has been possessed of a devil if ever anyone has. In a few months he quite suddenly died. In sawing open the skull, at the point of the small scar on his forehead, the saw came directly upon the butt end of a conical bullet, two-thirds of which projected through the skull, piercing the membranes, and into the brain. The internal table of the skull had been considerably splintered by the ball, the pieces not being entirely separated, and there was evidence of severe chi'onic inflammation all around, and quite a collection of pus in the brain where the ball projected into. Here was the devil that possessed the poor fellow." Dr. Towle does not indicate precisely the anatomical lesions in this case, but it was the injury done, as in the case reported aboAe, in the frontal convolutions of the cerebrum, in the part assigned by Terrier and others, to the organs of the moral and intellectual faculties. I am not aware of many recorded cases of moral insanity due to definite ascertained lesions of the cerebrum, but I have little doubt that in both these patients, their erratic moral course was directly due to the destruction or irritation of cei'tain definite regions in the brain, the functions of wliich exact investigation has yet to determine. CASES ILLUSTRATINC; LOCALISATION IN NERVOUS DISEASES. 121 A SERIES OF CASES ILLUSTRATING LOCALISATION IN NERVOUS DISEASES. By J. W. Springthoupe, M.A., M.D. Melb., M.R.C.P. Lend. Physician to the Melbourne Ho^ipital and Lecturer to the University of Melbourne. The following series of cases is brought forward as typical of many interesting features of nerve diseases, as a record of careful work in the department of neurology, and as further evidence of the degree to which localisation may be carried in such department. Age and etiology are also noted, since they are frequently inseparably connected with the nature of the lesion, but questions of prognosis and treatment are untouched, as being likely to complicate what is intended to be kept simple. Cases 1 and 2 illustrate some of the finer points in the localisation of spinal lesions. It was thought unnecessary to include cases illustrating the ordinary diseases of the text-books. Lesions in the internal capsule are then illustrated, both of the right capsule and of the left ; both of rupture and of occlusion ; both of the lenticulo-striate and lenticulo- oi)tic arteries, and of both combined. In all these, the symptoms and causation may be said to present their typical features. A case is added (Case 7) in which a cortical branch of the middle cerebral artery may have been the seat of the occlusion. Coming to the cortex itself, cases are recorded of probable implication of the arm centre, and of certain injury to the leg centres, as well as of lesions, irritative and otherwise, of the ascending frontal and parietal convolutions, and of the lateral and inferior regions of the cortex. Cases 20 and 21 are also presented as illustrating weakness of the brain area as a whole. Some typical brain tumours are also described and localised — one of the pons, one of the fourth ventricle, and two of the cerebellum. In the first three, a post-mortem examination disclosed the nature and site of the lesion ; in the fourth an operation was performed, which gave relief from some pressure symptoms. In all, the details showing the advance of the tumour, the fresh symptoms produced, and the time required to jiroduce them, may be accepted as strictly accurate. Lastly, two cases are jiresented,, in which localisation was diagnosed as probable, once by myself, once by others. In the former, i)eripheral irritation, ovarian in origin, in a person with a local brain instability, was found to be the actual cause ; in the latter, operation showed the case to be one of chronic hydrocephalus and not hydatid cyst of the left frontal lobe. Appended are the Tables of Cases : — 122 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. 03 (S -a P. The interferences with sensation and motion as found by myself, and the site of the injury, as verified upon the patient, exactly correspond with the experimental results obtained by Ferrier. Tlius, the ilio-psoas, adductors sartorius, the extensor femoris, and peronei, which are regulated by the third and fourth lumbar nerves, were uiiaff'ccted. Ferrier found that the fourth and fifth cervical were the motor spinal roots for the Deltoid, Romhoids, spinati, biceps, bracliialis anticus, supinator, longus, the exten.sor and serrate muscles ; none of these were aijpreciably affected. The si.xth presides over movement and nutrition in the latissimus dorsi pecto- rales, triceps and pronators. The seventh over some of these, the teres, sub- scapularis and hand flexors. The eighth over the flexors of wiLst, fingers, ai d hand, the extensor of t!ie wrist and triceps. And the fiist dorsal over the thenar, hypothenar, and interosseal muscles. Most, if not, exactly all of these were found affected. Patient had been treated foraoute rheuma- tism for the first five weeks. The arm and face fibres of the internal capsule probably implicated simi)ly l>y pressure, the rupture being behind" the knee of the capsule. IK Contusion of the spine implicating the exit of the fifth lumbar, and first and second sacral nerves of the right side. Poliomyelitis anterior acuta,commencing in the right lower lum- bar and first sacral regions, implicating mainly, bi-laterally, the anterior zones between the sixth cervical and the first dorsal. °2 |l After the injury, walked home ; complained of girdle pain round lower waist, with tenderue.ss of right side of upper sacral and lower lumbar vertebra;, weak from the knee down. Pains in leg, especially the iiibtep, stitfness of the part ; no reflex to tickling within a week Weak in the following movements- flexing the leg on the thigh, raising the os calcis, walking, moving the ankle laterally and up and down ; could not move tlie foot or flex the big toe. (Gradually impiwed. In three weeks, sensation normal, but foot dragged, and big toe not properly flexed. Suddenly pain and stiffness in right calf, and in right side generally. Fourteen days pyrexia, with pro- fu.se unpleasant sweating, then pains hi Lateral and confined to the arms. Paresis and paralysis followed, with atrophy ; both fairly symmetrical. Two months later, slight wasting in right calf and thigh. Flexion still weak. Forearms semi-flexed, semi-prone ; fingers extended and abducted. Can- not extend the elbow, flex the fingers, or rotate the wrist. Shoulder movable, but cannot touch the occiput. Electricity detected wasting in the ]>ccto- rales, latissimus dorsi and triceps, in the flexor muscles of the fore.arni, the thumb and interossei, posteriorly, with little or none in the radial aspect and supinator longus. Later on, the flexor and thumb muscles, the interossei, the abductor minimi digiti especially wasted, with local coldness, lividity, and denuded aspect, but flexion, rotation, abduction, &c., returning. Some slight atrophy remaining in right leg. Right liemiplegia. No unconsciousness, headache, or dizziness. Leg affected more than arm, bluer, colder, but no hemi-ani«thesia. Still, increased knee jerk, ankle clonus, leg dragged; aim almost normal. No deviation of mouth or tongue on attack, though speech thick for two months, and whistling im- possible. O Railway Accident — a blunt fragment of wood striking him on the right side. a S 5 Rupture of small tense artery three months ago. u o <5 1 o to •* OS s s - oi m CASKS ILLUSTRATIXr; LOCALISATIOX IN NERVOUS DISEASES. 123 1 "§.2 — a tt ' — — 2 - C"^ .^ -.J „ «~ 5 rt ■ -y ^ >< a ■""-■ « a ^ .5^ = ^.2 6 -1 1 i 1^ -.• 1 '-S a ^ ■g 5_ IJ =^.2 1 ^•5 a ii ^111 ti 33*5 H J f < a "3 c ^ '"^ S '^ a S © ^ -^ "3 - -■ ■^ Z ii — ^ S 3 O a t2 l!"3 ~ *3 'a tp-g a 1 5 a 5 ■~ 3 a rs a 2 w S 2 5 be — — 5* 3 ^ ""S _x a s 2 S-I3 a l"- *" S to 2« g i3 P ij c; 1 i"i G H S c5 -^ 1 "T"" 5fo .2 2 a a a - _g3 _ -. s 2 '^ a _a >• a 8 5 111 a - ^ a a "S ~ u 2iJ " ^F— t^ "S t2 "c :3 ^ »» .-^ c; ^ "a ■1 V4 . to 3 1 S = o* a S a.5 S c ^ 3 ^ "5 H S M .5 t! ti H J M (lI " - " -*3 ^ 2 To a fa to 1, 1 i "2 1 g rt o u a.i< a -3" 1 i il „• a — a To 3 'to~"2 -a « i §ga a :^ >■ i a .2 of II •H..2 If a Eli" '? 3';a II £ c'H.'i ^53 3 2 "^ o"^ to a 'a '"' ■3 a a ^ i -5 3 3 i 5 d 3 a K a^ „ a a TS to if 1 to a To 3 1 ^' if" a .:<: rt a 0- .^- = 5 :2 1 1 a 3 a II s -3 = 1 "a ^* a 2 X 2 " — ? '='5 "a i^^2 a ^ ci a •^ a S !0 O III o a .3 a S "^fa c to . fe St2 11 i 1 a 2 i< ^= re To" 'S •a I. a ■2 — ° «| ^ s 5 Has -*^ 2 "- "S 5 a "1 a!^ « — 5 s.'j; a| = |'| - - rf ? ?■ ^ a ;o' t- IZ3 >-] E" m a -*i _^ g ^ s ^ Q a ifi 1 ? 6 c 22 a 1 •<: si "l^' o c3 a 11 2 a a an 1 a S ^ « a ""^ r^ 2 -M iC W c; vi > 5 u3 -* C-. *0 7i 2^ 1 a 2 ^ — ' 2 c .2 "5^ - o « ■is i" '5 2 S ci « » 0" — a _>> fe* cs 2 P +3 ,S ^ 'B V5 "=? "? .S ^ 2 ^ A a s o «. 2 m tc g ■« s rt nil- i « - ^ Ji-2 nil -^ „^ to +^ -^ .SS'lla^l •5 P a _"6p .5 ''^ 6 — .2 "5 ■^1 •^ a 2 ci "3 S ■§ to 9 2 -S '= 1 g-J S +3 a J'i .1^ " 5 S-^ a ^ = -^ s a g ^ « " 5 111 '^ >.3 11| lit s l-s " a o o =e.a.a a ^ ^ |00 ■7? ^•'53 --2I ill ^ '-^ >> ^■ C: a . . a> a "■ Mm 3 — 5i > S 2 ^ (u a c a 5, -S M- '^ "S '-^ " .a "S 9 11 Nil! a § Jig.S8^SSg to g p 60 a 1 III! lip a) '^ — "^ a « „-.i % l*^ ^ ^ s 1 t- S ^ Q) ^ If 51 11 IPIl i^|loi irl: s 5 gp 2 a » 33 s Si & III § a -£ a s a — <; p: oj s -§-.- = ! j5 -p . . ;g -g 2 3 bo . r a -^ •- 3 £ a '^ 5 S.a;.o cs 3 £ ^ fe fa H <« . -^ 2 = "3 p X i^ *=• S u 00 D ?= = a' -4 ^ i c3 S i" b 2= ill ^ S* = "2 ll!il H P p 5111' 1 £i^| S 2 .2 S :« S M ti H ■2 = 5 b to . 2.2 -2 5.2 5 -^ ..^ .3 ~ = ;-! •^"isg-^g^^-s-^ " - S c 'z :: u. o 'ii g-3^ 2 2 3 s|'i>s nil III Jl S ? C *i ..i ri< O — i> O P s H - - -" -llflji- «•='-«-= --Si's rt so ^ = "*^ .2 S to— ■2l;§|"'c-2'-Sl§ o ?? S -" « J* 8 °rt 5 =*- 5."— w2 r'" =s ? ""2«— oa Q'3'3 "S § i o 5- 5 .2 •? £ S "S .-S -^-.60 1 a,"! j^'5 g i -=-■1 sgioi-s^o 1^ .Jl2.!"«i «|l|.2 = i2 S -i 'i^ ;* 5 £ qa £.2 ^H % -^ l|tl|||| "o -".S 'i O "o -2 t^ llildtii 11=11 1 ^ j::x i. 1 lliillilii a < O " ^ c c II S . - a 1 a> o I- •< i (N 'J' e X 1 "5 1 02 s S [^ eo -^ ■< y 126 INTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. s In eight months, this tumour seems to have grown from a size simply irritating the pons to that mentioned. Its pro- gress may be traced in the symptoms The locality of the headache, again, is noteworthy. The neuroparalytic ophthalmia occurred oidy when i>ressure on the Casseiiau ganglion had becimie possible by the extension of the tumour. Another case of localised lesion, in which the extension of the tumour can be traced in the symptoms as they arose. Tumour the size of a small orange resting on left pons, impli- cating the left seventh, eighth, sixth and fifth cranial nerves in the order named. TiTmonr of the fourth ventricle, pre.ssing first ou the spinal accessory and vagus, sjireading forwards to the right side, and pressing on the right sixth and eighth, the facial and hypoglossal nuclei, being deeper seated, escaping. The fifth somewhat im- plicated, also the valve of Vieussens, the third and fourth, and finally, the cor- pora quadrigemina. Considerable serosity of the plexus, and ■- }iS 1|£ .S 5 3 O Five months pieviously, left hemiparesis without hemi-ana3.sthesia ; also paresis of right arm, and severe right parietal headaches. Now, paralysis of left seventh and eighth nerve; added, and marked choreiform movements of all limbs, esiiecially the right arm, with ulceration of left soft palate. In sixteen days, diplopia an! ■■" a ^ 9 "^ 3 cS >^ w When I saw him last, h peration seemed advisab ts by the operation itsc localised tumour was fe tempt was not made inl ■essure-symptoms. 1 ma ^ "•" * S 2 •U - C J) rt'" < -2:1=1 •5 = = 1; 3 1-""-= X a .2t|£-?o 5|| l^.i £-£3" - ° "5 p 3 aj 3) o c *^ ""Iwlti 1 •= £ ci -a "S 2 2 -" = = o s "^ aj o ■•- i. O i M 2 — a H a ^■1 ^ . a S^ 5: "3 o a > a B ° 5 ^a s 2 !o 2 '-3 2 ■J "s ^ 5 S ai a ^ 53 6 2 S 3 a 53 >>;= ;■■"«-? J.SJ"3.a-| ^il=/=^ .= 1 1-- jcijis go «l- s a •=l-iil .= pearances like albumenuric r No kidney disease detectible. The hajmi appeared suddenly, with sudden loss of he; right ear. Right eye, vision almost gone. I speech thick at times, and gait somewhat un: n August 1SS7. Patient remained under my observation till alising symptoms had appeared. His subsequent history is i mcertainty as to the nature and site of the tumour. Little. cuing through the occipital bone, some one-third of a teacup c left .supero anteroparietal region, also with negative result ve all erred in not locating the tumour there. The re.sult of tary Section dollar nie from the ple;isnre of hearing Ur. Mau( Somnambulism as a child. Congestive heatp S jj .5 . E|£2 H ^ •< ??a^ = .9 o o to 3 ^ hi ^^ 23 £ 2 1 sJ! < liiflt-l "■2 a -co O '3 X ^ "« U2 &3 ^ §3'^ ■^ cla s s ,x = c z:^-^ •^ (M < CI -f to ? — '.5 "5 >> .3 » - - a D '5 roduced as lilt from ] ase is a laiiy diffe iven. No aving been he writer iglittem])Oi f sei)tic inf owever, en I'as detectei fter the ope ured. troduced effects of the instal site in th within th not in the •*^ w U 1^ iC.,3 +i i, o .::: > c3 o •^ '- ?-|11^ ■SS-r-i^-i-S ight ov.arian a: tubal disease ; t ovary half filiroi half soft and friabl tlie tube in a com tion of well-inark h.tmato-salipynx. H* -^ M =3 s e olecular in the brain i with pro manent v: c n s e q changes. S « 1 ke of average y unaffected ; ued attention re in the occi- bloodshot, on ; retina fairly ntil the sun- now unequal aracter, more occurring in food, though indescriliable ,r. Symptoms ,, with ajqiear- Throbbings of neck. No alid from the than eighteen a seiiticemio ee and a half ily history of ■en subject to ras, siinstro ice. Memor y for contin iression, mo inful, and Sight good ; y upset ; u igorous, but bursting oh ital regions, staste for g good, but the right ea halmic veins in right eye, 1 right side omplete inv ins for more ating from placenta thi was a fam: d always be ti K ivelve months ago in Mad severity ; no paralyses sii intellect keen, but capacit almost nil. Feeling of op] put, with eyes weak, pa attempting steady work, normal. Stomacli quickl stroke, all the functions v: to ordinary work. ce 3:3.= .5:S ^-S^^-^^^cj b K nbearable headaches of in right parietal and ft paroxysms. Extreme seldom vomiting. Hear noises almost constantly of pressure mion both ojil ance of incipient neuriti in right jugular. Pains spasms or paralyses. A head and stomach symp months, the symi)toms attack following retainei years iireviously. Tlieri migraine, and patient 1 attacks herself. H tJ , CJ= i .2 •- •" , -S' c U 'C o H .« g J — ^ >. a> i^ ""ci .- o o ^ c — • ;: •? .23 "S s f.Srtl x Ph u n ^ G i _o "3 u E ■Jl tS (2 rfi ^ Ol 0\ 01 o A CASE OF IIAYNAUD's DISEASE. 129 A CASE OF KAYNAUD'S DISEASE. B}^ David Grant, M.A., M.D. Ediii. Lecturer ou Materia Mcilica in the Uuiversity of Melbourne. The condition which was lirst described, from its ultimate manifesta- tion, as "symmetrical gangrene," and wliicli has since, according to the stage which in nny given case was most cons{)icuons, been variously recognised ;is "local syncope," "local asphyxia," "local ischa?mia," "local cyanosis," will probably, and justly, take its place in nosologies under the name of Kaynaud, who first collated the recorded cases, and formulated a rational theory of its pathology. As it still ranks among tlie rarer neuroses, a l)rief descrii)tion of a case which occurred recently in my hospital practice, and which, through not absolutely typical, was sufficiently well-marked, may be of some interest to the members of the Congress ; and I therefore pro'.-eed, without further preface, to recount its leading features. History. E. T., set. 38, married fourteen years, without children, engaged as a seamstress, came under my treatment at the Melbourne Hospital in July 1888. Her health had always been good ; she had had no acute illness of any kind, but had sutiered from chilblains in girlhood. Her pr(!sent illness began in the winter of 1885. iShe first noticed that the terminal phalanges of the fingers became quite white and painful, this condition lasting at first about a quarter of an hour, and ceasing after friction or exposure to the heat of the fire. During the winter it gradually extended upwards, and affected the second phalanx ; and after exposure to sharp cold, the whiteness was followed by a dark "blue-black" a])pearance, with severe pain. The left fore-finger was particular atlected, and seems to have been treated as a whitlow, the end being poulticed and incised, but no matter came, and xcry little blood followed the incision. Soon after this, the nail dropped of. Improvement occurred during the summer, Ijut during the following winter (1886) the condition became worse, and the nail of the left middle finger was lost. The affection has been present more or less continuously ever since, and as gradually become more painful. The whiteness and deadness of tlie lingers occurred even during the warm weather of the summer, but was especially produced by cold. The pain has been greater during the present winter, and most of the fingers have lately become red and swollen in the intervals between the attacks ; but when the attacks come on, these red and swollen fingers become quite white, cold, numb, and much smaller in size. Causatiox. On this i)oint, nothing definite can be ascertained, except that she had much woriy and trouble before this ailment began. Hemicrania, which is sometimes associated with the disease, is not known in her family, nor is there a family history of any other neuro.ses. There are no menstrual irregularities, and lier other organs and systems are normal, K 130 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. except (1) the digestive, which is occasionally painful. The tongue is furred, and there is constipation. (2) The heart, where there is evidence of aortic obstruction, in the presence of a faint systolic murmur, loudest in the aortic area. Local Appearances during Attack. (1) Stage of Iscluemia. — Her condition last August was the follow- ing : — Her hands are always more or less jiainful, and usually in a state of redness and swelling. On first rising in the morning, the fingers, up to the metacarpophalangeal joint, become perfectly white and dead, and extremely painful. The bloodlessness of the fingers, quite symmetrical, accompanied by extreme coldness and ]iainful antesthesia, and shar[)ly and abrupitly marked off from the normal warmth and vascularity of the metacar[)al region, was frequently seen by me, and pointed out to the students. The extreme contrast and abrupt transition from absolute cadaveric pallor to the natural glow was most striking, and totally different fi'om the diffuse coldness and gradual transition to healthy warmth of surface so commonly seen in those with weak circulation or heart-lesions. This stage of iscluemia iisually lasted through the fore- noon, and as the day became warmer, the whiteness was replaced by a bluish-black appearance, which succeeded immediately to the maximum whiteness. (2) Stage of Cyanosis. — In this stage, which was rapidly develoj.ed, and several times displayed itself while the patient was under observation in the out-patient room, the cyanosis, or local asphyxia, was extremely marked. The digits began to recover their warmth, and the Avhiteness was rapidly replaced by a dee}» indigo hue, almost passing into black. This stage was much shorter than the first (lasting usually from five to ten minutes), and appeared to osve its existence to the fact that the })rimary spasm, affecting both arteries and veins, disappeared first from the latter, and permitted the regurgitation into the capillaries of venous blood which had been detained for a considerable time in the smaller veins. This state was immediately succeeded by a stage of eiythema, in which the fingers became red and swollen, and the [lain was a little diminished. (3) Stage of Hypercemia. — Formerly, the |)ain ceased entirely at this stage, l)ut now (i.e., in August 1888) the right forefinger and the left little finger are permanently red and swollen. (4) Gangrene. — On August 12th, I noted that " the left little finger is red, swollen, and slightly tender ; there is a small cicatrix on its tip, where a black patch formed some weeks ago, and a similar appearance is extending under the nail, which threatens to separate. A similar dis- colouration is visible on the dorsum, on the pidp of the last phalanx, and under the nail of the right forefinger ; and a slight loss of skin on the end of the right ring-finger, which was preceded by a black speck." These losses of tissue in skin and nails were very small, but distinct enough, iaivolving the loss of two entire nails, and of several small j)ortions of skin. None of the interesting nervous symptoms, such as aphasia, transient blindness or deafness, were observed in this case; nor was there detected, at any time, htematuria or albuminuria. A CASE OF RAYNAUD S DISE.\5E. 131 There were no cardiac symptoms. The aortic murmur was a very- obscure one; and as ah-eady said, tlie local pallor was very different from that sometimes seen in heart-disease. The toes were symmetrically affected, but much less severely than the fingers. The intensity of the symptoms was always increased by cold, and as the spring advanced they have gradually abated, until now there is only a slight redness and fulness of the fingers, with scarcely any discomfort. Treatment Practically Useless. Treatment has been of little avail. It has been conducted on three lines : — (1) An attempt was made to remove the vascular spasm, jjartly by acting directly on the arterioles l)y means of nitro-glycerine, partly b}' diminishing undue excitability of vaso-motor centres by the agency of the bromides. Tlie former, in one minim doses of the 1 per cent, solution, pro- duced disagreeable physiological symptoms, without the least improvement in the local disturbance, and was soon abandoned. The latter, alone or combined with belladonna or valerian, were better tolerated, but equally futile. In view of the cardiac lesion, although there were no signs of defective compensation, digitalis had a fair trial, on the theory that it might possibly overcome })eripheral resistance, but its action on the arterioles I'endered this in theory almost a forlorn hope ; and, in fact, it also was useless. Spirit of nitrous ether, as a vaso-dilator, was also vainly tried. (2) The changes were rung on the various vascular, blood, and nervine tonics — chiefly iron, strychnia, and cod liver oil ; but in no case did it appear that an}' beneficial effect was produced. (3) Electricity, in the form of the descending stabile current, which produces relaxation of the arterioles, hashad a pi'olonged trial, extending over several months. The patient found that the attack was shortened slightly by this ; the ischtemia passing into the stage of erythema some- what sooner, but no permanent good was done. The spasm returned with undiminished intensity on the following day, and the results of the electrical treatment in this case hardly bear out the conclusions of Raynaud himself as to its efticacy. As minor details of treatment may be mentioned, the use of friction and the wearing of warm gloves, which slightly palliated the severity of the symptoms, but had no effect in preventing the recurrence of the daily paroxysm. Remarks. The diagnosis in this case was based upon the presence of extreme vaso-motor disturbance, characterised by three well-marked stages of ischaemia, cyanosi.s, and erythema (or rather hypera^mia), affecting the extremities symmetrically, excited or intensified by cold, and leading to superficial necrosis of very small portions of nail and skin. The presence of a valvular lesion of the heart, and the history of chilblains in child- liood, caused at first some hesitation in diagnosis, but further observation removed any doubt as to the existence of a true vaso-motor neurosis, cattsing local disturbance of circulation, which could not be dependent K 2 132 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. either on back-working, or on defective cardiac power. In the descrij)- tion of this disease, given by Dr. Allan Starr, in Pepper's " System of Practical Medicine " (the only complete account to be found in any systematic work), absence of cardiac disease is specified as a conditioir of the diagnosis, but this appears to me to be an unnecessary require- ment, inasmuch as the local phenomena are sufficiently characteristic to be identified even in the presence of heart disease. Another point of special interest in this case is the very short duration of the attacks, and their daily recurrence— all the stages of the disease being daily manifested. Pepper says that " the shortest duration of a single attack has been ten days, the longest five months." But in this case, a complete paroxysm was passed through every day, showing typically — (1) local ischajmia ; (2) local cyanosis ; (3) local hyperajmia, the first lasting a few hours, the second only a few^ minutes (not more than 15), and the third being present in a varying degree until the beginning of the next paroxysm. This daily recurrence of paroxysms was a striking feature of the case. Nature of the Disease.— Old Theory. Until a few years ago, there were no post-mortem records of cases; and the theory originally propounded by Raynaud, as a deduction from clinical observations, viz., that the disease is a vaso-motor neurosis, was universally accepted, the only difference of opinion being on the question whether the vaso-motor irritation was in the vaso-motor centre itself, or was excited by peripheral irritants. I find, however, in Virchow and Hirsch's Jaliresbericht for 1888, an abstract of a paper by Dr. Goldschmidt, in Revue de Medicine, entitled, "Gangrene Symmetrique et Sclerodermic," in which he describes in detail a case of Raynaud's Disease, " which was complicated with the appearances of an extensive •scleroderma, in a woman cct. 43, previously healthy. . . . After five years' existence of the disease, there finally appeared symptoms cardiac and renal (albuminuria). The patient died suddenly in consequence of cardiac failure (Herzinsufficienz). At the auto})sy, the essential feature was a widespread endarteritis and endophlebitis terminalis, both in the gangrenous and sclerosed parts; the same could be demonstrated in the ter- minal arteries of the kidneys and lungs. It is noteworthy, that changes in the peripheral nerves could not be demonstrated. Brain and spinal cord were not examined. On the basis of the anatomical data, the author regards it as certainly established, that in sclei-oderma, and in Raynaud's disease, we have to do with the same pathological process in different phases of development — an endarteritis terminalis, wuth regard to which it must still remain doubtful whether it ow^es its origin to vaso- motor disturbances, or is of micro-parasitic source." I translate this abstract in full, because it is obvious that every post-mortem record of a rather obscure disease is of importance as a possible source of light, and I regret that I have no access to the original paper, to which reference is made for the clinical details. The new theoiy here put forward is totally at variance with that hitherto received, inasmuch as it takes the disease out of the category of neuroses, and places it among chi"onic degenerative affections of vessels. The two conditions maij have coincided in Goldschmidt's case, for there is no incompatibility between vascular s[)asm and vascular inflannnatiou. But endarteritis and A CASE OF Raynaud's disease. 133 emloplilebitis, j^er sc, appear to me to be totally inadequate to explain the phenomena of Raynaud's Disease, for (1) its greatest frequency is between the ages of 15 and 30, when endarteritis is rare : (2) only two eases have been observed itx patients as old as 50, when endarteritis is common ; (3) endarteritis is a chronic condition, leading to permanent oi'ganic clianges, while Raynaud's Disease consists of definite attacks, witli well-detined " stages," ending in recoveiy, and followed in a large pro])ortiou of cases by recurrence ; (4) in my case the condition was distinctly paroxysmal, and this character is also manifested by the transitory aphasia, blindness, albuminuria, hematuria, and glycosuria, which have been sometimes observed ; (5) endarteritis would scarcely account for the precise symmetry of the local appearances, which is, on the other hand, not only consistent with, but characteristic of, a purely neurotic origin. This new theory may, therefore, 1 venture to think, be set aside as insufficiently supported by positive evidence, inadequate in itself, and inconsistent with clinical facts. Reverting to the accepted theory, that the disease is a vaso-motor neurosis, the question arises whether the vaso-motor irritation originates in the centres themselves, or is reflected from the periphery. Raynaud regarded it as central, mainly on the ground that "galvanisation of the spinal cord modified the arterial spasm," and the partial benefit derived from electrical treatment in the case here reported bears in the same direction. Rut it would be rash to draw a positive conclusion from a single piece of evidence wliich is still in want of confirmation, and it appears that the good effects of galvanising the cord (assuming that they are proved) may be due, not to the removal or suspension of morbid changes in the vaso-motor centres themselves, but to a diminution of their normal excitability, rendering them insusceptible to the action of periphei-al irritants. Stronger arguments, in favour of the centi'al seat of the primary disturbance, appear to be found in the intensity and persistence of the arterial S])asin, in the occasional paroxysmal character of tlie attacks, and in a consideration of the alleged or suggested sources of reflex irritation. The latter are all of a very general kind. Thus, " Wei.ss believes that the condition may occur in response to irritation arising in the skin, in the viscera, or in the brain " (Pepper, p. 1261). But cutaneous, visceral, and cerebral irritations exist in hundreds of thousands of cases, without producing symmetrical ischsemia and gangrene, and in any case in which tJiey do, it becomes necessary to assume the existence of some undue excitability of vaso-motor centres — in other words, to admit that the essential condition is a central one. Here, we may refer to the analogy of epilep.sy, where all sorts of peripheral irritants may come into j^lay as exciting causes of the central dischai-ge. To this group of neuroses, including epilepsy and hemicrania, Raynaud's Disease may most reasonably be referred. An additional item of evidence, in favour of a central change, is furnished by the title of a paper which I find in ScJuniJfs J alirhuclter for 1887 (Vol. 216, p. 310). The paper is by Marfan, and is entitled " Syncope locale des extremites snperienrs a la suite d'une commotion medullaire" [Arch Gen. 7 S. XX., p. 485, Oct.) Here again, I have no access to the paper, and no abstract is given by Schmidt ; but the title implies that the disease was consecutive to concussion of spinal centres. 134 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. The existing evidence is not yet sufficient to justify a positive con- clusion, but its weight is decidedly in favour of the tlieory that the disease is of a central origin. An attempt has been made to explain the symptoms of " Raynaud's Disease," as the result of peripheral neuritis. Thus, in the British Medical Journal for January 1887 (p. 57), Wiglesworth reports a case under the title of " Peripheral Neuritis in Raynaud's Disease (Symmetrical Gangrene)," and in the discussion on this paper at the Pathological Society, reference was made to similar observations by Bowlby, Pitres (2 cases), and INIountstein, of Strasburg. In Wigles- worth's case, advanced chronic inflammatory changes were found in all the nerve trunks of the limbs, but the clinical details of the report do not appear to justify the diagnosis of Raynaud's Disease. The case was, in fact, quite obviously one of peripheral neuritis, with epileptic dementia, in which there was great atrophy of muscles, and in which the gangrene (leading to the loss of fingers and toes) was the result, not of deprivation of blood supply, but of injury to the tro))hic nerves. There is no history given of vaso-motor phenomena, which are the essential feature of Rajniaud's Disease ; and the value of the case is further impaired by the fact, that advanced granular kidneys were also found. Peripheral neuritis is as incapable as endarteritis of accounting for the paroxysmal character of true Raynaud's Disease, and few competent judges will be disposed to accept the conclusion of Dr. Wiglesworth, that his observations " tend to take Raynaud's Disease out of the category' of neuroses, by giving it a tangible material lesion to rest upon." The obvious error in this case has arisen from the condition of " symmetrical gangrene " having been identified with the lesion described by Raynaud, and regarded as its essential phenomenon. As a matter of fact, symmetrical gangrene is no necessary result of the vaso- motor disturbance which constitutes the disease, and is much more likely to be caused by trophic nerve lesions, either centi-al, or as in Wigles- worth's case, peripheral. It is desirable to em.phasise the fact, that symmetrical gangrene is a secondaiy result of various primary lesions, and that it does not, ])e.r se, form a disease type. It would also be well if the lesion now under consideration could receive a single descriptive name, based on its pathological cause or chief clinical features. If I were to describe my own case in this way, I should call it " paroxysmal recurrent isclipemia;" but this name would probably be inadequate in many cases, and as the clinical phenomena are variable, and the essential pathological cause is still obscure, it seems advisable still to retain the convenient title of " Raynaud's Disease." Addendum. Since the foregoing paper was read, I have just received the British Medical Journal for December 8th, 1888, containing a paper by Dr. Affleck, on Two Cases of Raynaud's Disease. For one of these the left foot had to be amputated, and the internal plantar nerve was found to " have suffered extensively from neuritis, and was undergoing degenera- tive change, many of the bundles being entirely destroyed, and replaced by fatty matter." The author remarks that, "it might, perhaps, be urged that this was a secondary result to tlie tissues of tlie affected parts, from the changes in them accompanying the gangrene;" and considering AORTIC INCOMPETENCE AND LOCOMOTOR ATAXIA. 135 tliat in this case the gangrene was extensive, involving the anterioi- half of the foot, so that " it was evident that every tissue in this part had perished," and considering that this condition had existed for nearly two months before amputation, it seems more reasonable to regard the degeneration of the nerve as a consequence, than as a cause, of the gangrene. It may be remarked also, that the appearances described and figured are those of simiile fntty degeneration (not, as in Wiglesworth's case, including hyperplasia, and other results of inflanmiation), so that there is the more justification for regarding them as indicative of ascending degeneration, consecutive to the gangrene of the parts which they sup})lied. The repeated observations of neuritis, or changes similar to those of neuritis, in cases of Raynaud's Disease, must be regarded as having an important bearing upon its pathology, but that neuritis is the cause, or even a necessary contributing cause, of the symmetrical gangrene, is not yet established or rendered probable by hitherto recorded cases. On this point, I would remark — (1) That the arrest of circulation in this disease is sufficient to account for gangrene, without invoking the aid of trophic nerve-lesion ; (2) tliat perii^heral neuritis is very common, and Raynaud's Disease comparatively rare ; (3) that motor symptoms, usually present in neuritis, are absent in Raynaud's Disease ; (4) that the sensory symptoms are obviously dejiendent on, or explicable b}^, the vascular disturbance ; (5) that mere neuritis cannot account for the distinctly paroxysmal t3'pe of the disease ; (6) that the occasionally associated aphasia, glycosuria, hfematuria, blindness, and deafness, all transitory, are entirely consistent with the theory of a central vaso-raotor disturbance, and entirely irrelevant to that of a neuritis. AORTIC IXCOMPETEXCE AXD LOCOMOTOR ATAXIA. By D. CoLQUHOUN, M.D. Lond., M. R.C.P. Lond., Dunedin. About two and a half years ago, I had under my care a woman suffering from mit.al incompetence, in whom there were marked symptoms of inco-ordination of the lower limbs, with abolition of the patellar reflex. Shortly afterwards, the first of the two cases, whose histories follow, came under my care. The symptoms presented seemed clearly to be those of locomotor ataxia, but on account of the heart lesion accompanjdng them, it seemed to me to ]>e not unlikely that the deficiency in the functional activit}' of the cord, in this and my previous case, was due primarily to imjierfections of the circulation. In a little more than twelve months, a similar case, also detailed in this pa])er, came under notice in Dunedin Hospital, and I learned from the Medical News, of Philadelphia, that the coincidence of aortic I'egurgitation and locomotor ataxia had been already discussed in the Berliner KliniscJie Wochensdirift. I take the following account of the discussion from the Medical News of July 7, 1888 :— " Bergerand Rosenbach, in 1879, called the attention of the profession, in a brief notice in Berliner Kliuische Wochenschrift, to the association of 13G INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. aortic insufficiency witli locomotor ataxia. They published notes of seven cases, without comment. In tlie following year, Angel, in an article in the same journal, entitled, ' The Coincidence of Heart Lesions with Tabes,' reported on a series of twelve patients suffering from locomotor ataxia, five cases in which there was the sign of aortic insufficiency, namely, a diastolic murmur, present however only after muscular effort, and disappearing during prolonged rest. The murmur was not heard at all in the morning, while the patient still remained in bed. This observer regarded the murmur in question as due to abnormal action of the heart muscle. " Groedel, whose opportunities for the study of locomotor ataxia at Bad-Nauheim have been very extensive, regards the occurrence of cardiac affections in this disease as wholly accidental. In this view, he concurs with Eulenburg and Ei'b. Between 1875 and 1879, namely, at a time when his attention had not yet been especially called to the subject, Groedel noted, in forty-three cases of ataxia, only two in which the signs of valvular disease were present. Between 1880 and the close of 1887, a period during which every case of locomotor ataxia was studied wath especial reference to the condition of the heart, valvular lesions were detected in only four out of one hundred and eight cases, and in no instance was he able to recognise the murmur of aortic insufficiency after muscular exertion, as described by Angel. Cardiac phenomena of a diflerent kind were, however, very frequently observed. These consisted of feeble action of the heart, increased frequency of the contractions, small pulse, faintness of the sounds, manifestations not oidy common in enfeebled subjects, buc also in those still well nourished and strong. In only two instances were these symptoms associated with the signs of dilatation of the right and left chambers of the heart." It is evident that Groedel's observations were made on patients whose primary disease was locomotor ataxia, and they can hardly be said to negative the possible connection between some cases of aortic insufficiency and the development of symptoms of locomotor ataxia. It seems to be a point worthy of obsei'vation, whether valvular lesions, accompanied by failing compensation, may not be frequently accompanied by symptoms such as are met with in locomotor ataxia. Pi-obably too, the prolonged action of this cause — failing compensation — may give rise to changes in the posterior columns of the cord, which may remain Avhen the failure has been partially recovered from. Dr. Moxon, in his Croonian Lectures on the Influence of the Circu- lation on the Nervous System, has pointed out that the blood supply of the cord is so distributed as to make the lower part of the cord especially liable to suffer from deficient force of the circulatory appai-atus. The su))))ly from the vertebral arteries has to be sup]>lemented by a precarious supply from below, the re-inforcing vessels reaching the cord along the strands of the canda equina, at an exceedingly disadvantageons angle. It seems hardly reasonable to dismiss such cases from consideration as merely coincidence, when the causes assigned seem fairly to account for the symptoms produced. I will now submit my two cases for your consideration : — A. H. S.,a gentleman, aged .55 years, consulted me first in Sej)tember 1880. He then complained chiefly of giddiness, especially on sudden movements, and of loss of sight for a few seconds under the same cir- AORTIC IXCOMPETKNCK AXD LOCOMOTOK ATAXIA. 137 eurastances. He had not been well for months, but had intervals of compai'ativc ease. For the greater ])art of his life, he had been a very strong and healthy man. He was born in England, but left it as a boy, and had worked as a digger in California, Victoria, and New Zealand, leading a hard life. He was more tiian usually active for many years, able to walk up hill, or run and .jump, with less distress than most men. He had never any serious illness, was married, and the father of ten children, all of whom were healthy. For some months he had noticed that he staggered in the dark, and that when he closed his eyes at the washhand basin, he could not balance himself. On rising from a chair, he said he would often stagger as if he had been drinking. Two years before, he had pains in his back and round the body, but these had not lasted long, nor been intense. There were no lightning or rheumatic pains in the limbs. He had for about four or five months difficulty in retaining his urine ; it came from him suddenly with some force. On examination, the urine was acid, specific gravity 1018, not albuminous, and normal in quantity. Both pupils were contracted, the right almost to a pin-point. His sight was, and had been, good. The patellar reflex was absent in both legs. He slept badly, di-eamed a great deal, and was drowsy all day. Digestive power was only fair. He was often bilious, but had no vomiting attacks. Bowels, as a rule, wei'e constipated. He was fairly nourished, but said he had lost about sixteen pounds weight in the last six or eight months. There was visible pulsation in the great arteries of the neck, and in the arteries of the arm, most marked when the arms were raised. The area of cardiac dulness was considerably increased ; there was heaving, diffused pulsation over the cardiac area, and the heart's apex could be felt about three inches below the left nipple, and two and a-half inches on its outer side. Tlie first and second sounds of the heart were replaced by murmurs heard towards the base, and conducted to the apex. The pulse was slow, about sixty to the minute, and presented the chai-acteristic sphygmographic tracing of aortic regurgitation. I have seen this patient at intervals since the above notes were taken. He has had several angina-like attacks, but has been able to attend to his business (that of a brewer) until within the last month (beginning of November 1888). His present condition is that of marked failure of comjjensation. There is a small amount of albumin in his urine, partly due to pus from cystitis. He has oedema of the feet and legs, and some ascites, and frequent and distressing attacks of dyspnoea, which are controlled by small injections of morphia and digitalis. There is no advance in the ataxic symptoms. The following case was admitted into the Dunedin Hospital on November 5, 1887, where he was under the care of Dr. De Zouche, and afterwards of Dr. Stenhouse. I am indebted to those gentlemen for permission to use their notes, and also for the opportunity of examining the patient from time to time : — James B., aged 45 years, a miller by occupation, complained on admission to the hospital of numbness in the arms and legs, and almost complete inability to walk. About a month before admission, he had severe "rheumatic" pains all over the body, but especially in the legs, from the lii{)s downwards. He was unable to pass urine ; desired to do 138 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. SO often, but on making the attempt, felt great pain in tlie penis. lie then came to the out-j^atient room, and Dr. Roberts drew off the urine with a catheter. He had subsequently great pain in the I'egion of the bladder for two or three hours, but was afterwards able to pass a little urine for a few days. During all this time his legs felt tired, and the left foot became numb. He has had shooting pains in the legs for years past. Twelve or thirteen years ago he worked in water for a day or two every week for some months. He has had no illness of any kind that he knows of, and has always been a veiy temperate man. While at his ordinary work, he was always a good deal exposed to cold. His father is alive, aged 76 years, and has always been healthy. His mother died in child-bed, and there is no history of any constitutional weakness in liis family. Patient is a tall, strongly-built man, very antemic and feeble-looking. There is visible pulsation in the arteries of the neck and arms. The pulse is full and bounding — the water-hammer pulse. The area of cardiac dulness is increased, and the apex beat is some distance to the left of and below the normal position. The first and second sounds of the heart are replaced by well marked blowing sounds heard at the base, mid-sternal region and apex. The pulse is 105, respirations 27, tempera- ture normal. The tongue is transversely fissured and red, the bowels are usually constipated, and digestive power is weak. There is deficient control of the bladder ; the urine is normal in character and amount. He cannot stand with his eyes shut ; patellar reflex is absent in both legs, and his gait is weak and uncertain. Muscular power is good in both legs. The joints are normal. He complains of feeling numbness over the mid-dorsal region of the sj)ine for about three inches of its length, and of a tender spot towards the lower end of the dorsal region, and first lumbar vertebra. The flexors of the left leg respond only slightly to the induced current, the flexors and extensors of the right leg res})ond freely. The skin over both legs is somewhat anaesthetic. Intelligence is good. He com])lains of occasional dimness of sight ; but there is no record of ophthalmoscopic examination, or of the condition of the pupils. He had symptoms of failing compensation of the heart. Dyspntea on exertion, &.e. After stajing for some months in the hospital, he left somewhat improved in his general condition, but, of course, with the special diseased organs unimproved. In these two cases, the questions arise : Is the condition that of aortic regurgitation, with failure of comjjensation, accompanied by locomotor ataxia as an accidental conq:)lication 1 or, do the ataxic symptoms depend on changes in the spinal cord, due to imperfect blood supply '? In both cases there is an absence of syphilis, which we know is a potent agent in ])roducing locomotor ataxia. In the first case, the patient was exposed to cold and wet, which may have produced chronic inflammatory changes in the cord ; but the second patient has been for years leading a particularly quiet, regular life. In both, it was impossible to fix exactly the date of appearance of the ataxic symptoms, but they seemed to be nearly coincident with the first signs of failing compensation in the heart. Again, locomotor ataxia is usually a disease of many sym])toms — there may be changes in the eye, in the muscles of the eye, gastric disorders, CLINICAL NOTES ON SOME CASES OF CEHEBRO-SPINAL FEVER. 139 skin troubles, joint atfections, lightning })ains, itc. In tliese two cases tlie symptoms of locomotor ataxia were limited to the want of co-ordination, wlien the eyes were shut or not available, the absence of the patellar reflex, and want of control over the bladder, with a few minor disorders of sensation. The nervous phenomena were such as might result from passive congestion of the posterior columns of the cord. In neither case was the disease markedly progressive, althougli it must be noted that the time for observation has been limited. It seems to me that these cases can be separated from ordinary cases of ataxia. I should be inclined to describe them as cases of aortic insufficiency, with ataxic symptoms. I think the evidence is decidedly against the suggestion, that locomotor ataxia has anything to do with producing aortic disease. But there is not sufficient evidence in the meantime to pi'ove, or disprove, that cardiac incompetence may give rise to symptoms of locomotor ataxia. It is with the hope that attention may be directed to this point, that I venture to place these two cases on record. CLINICAL NOTES ON SOME CASES OF CEREBRO- SPINAL FEVER. By William Finlay, M.D., Bathurst, N.S.W. Case I. On the evening of the 16th April, 1887, I was called to see a young man 21 years of age, a labourer, some fifteen miles distant. He had always enjoyed good health until some eight days previously, when he was suddenly seized with chills, vomiting, intense pain in the head, back of the neck and spine, accompanied with great Aveakness of the lower extremities. He was conveyed in this state to Bathurst, on two occa- sions, to consult a medical practitioner. He gradually got worse, and I was informed that he had taken " a fit " the previous evening, and force had to be used to keep him in bed. During the da}-, he had been quieter, but towards evening was srettinij: more delirious. o o O On examination, I found the tongue whitish, large, and fiabby ; the skin cold and pallid ; hyi)erjesthesia well marked over the entire body, and especially over the cardiac region ; photophobia and hyperiemia of conjunctiva; temperature in axilla, 9G'' F. ; pulse 48, and rather full ; respirations shallow and increased in frequency. The head was drawn back to nearly a right angle, the back arched forwards, the thighs and legs flexed and somewhat rigid, but could be easily moved. For a time he would remain quiet, until a paroxysm of pain would seize him, when lie would toss about, and uttering a piercing shriek, exclaim "Oh! my liead!" requiring force to keep him in bed. He complained of pains all ovei-, but worse in the head, back of the neck, and spine ; the paroxysmal attacks, he said, felt like some one driving a nail into the ciown of liis head. 140 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. While I was present, he was seized with a tonic convulsion, and his body bent like an arch. This convulsion lasted two or three minutes, when he again resumed his former position. One drachm of the liquid extract of opium, combined with ten minims of the tincture of digitalis, was administered ; and a mixture, containing ten grains of the bromide of sodium, thirty grains of the hydrate of chloral, fifteen minims of the ordinary solution of the hydrochlorate of morphia, and ten minims of the tincture of digitalis prescribed, to be given, well diluted in water, every four hours, till the ])ain in the head was relieved. On the following day, August 17th, I was informed that he had several convulsions during the night. The temperature was 96° F., pulse 60, respirations shallow and frequent. Still complains of his head, and aches all over ; seems stu{)id and apathetic ; retraction of head and aching of spine still present. A ^^apular eruption on forearms, consisting of a few whitish raised spots, about one-eighth of an inch in diameter, and feeling exactly like a split pea under the skin. Seemed much weaker. During the next twenty-four hours, he was for the greater part of the time delirious. The temperature in the axilla was 98° F., pulse 68, i-espirations shallow and frequent, hypera^sthesia still present ; shrinks when pressure applied to the skin. Papules on arms more numerous, and now found on legs, with mottling of arms and legs, but only extending as high as elbows and knees. For the following three days the stupor became more profound, the pulse inci'eased in frequency, the mottling on the arms and legs was of a duskier hue, and on the ■22nd, I discovei'ed a large, irregular-shaped, reddish patch on the left infra-dorsal region, extending in length about four inches, and about two and a half inches in breadth. He remained in the same condition till the 26th April, 1887, when the tongue was found very much swollen, and almost black, and several reddish-black spots had appeai'ed on the legs. During the 27th and 28th, the si)ots on the legs had gradually increased in size, and coalesced. He died early on the morning of the 29th, and in a few hours the whole body had become almost black. No autopsj' allowed. Case II. Was that of a boy, seven years of age, who was just recovering from an attack of enteric fever. I was asked to visit him on the evening of the 13th May, 1887. He was vomiting, and complained of great pain in the back of the neck, and every little while would cry out, " Oh ! my head !" He was very irritable, and showed great aversion to anyone approaching him. The face was flushed, the tongue white and flabb}', the temperatui-e in axilla was 102° F.; pulse 130; respirations normal. Prescribed a mixture containing four minims of the tinctui-e of aconite, five minims of the compound tincture of cinchona, and two grains of the iodide of sodium in each dose ; to be given, well diluted in water, thrice daily. During the following night, he was wildly delirious, and on the 14th I found it im]>ossible to take the temperature or pulse, on account of the ]iy])era'sthetic condition of the skin, and his attempting to strike, kick or bite, if you approached him. The head was then retracted, with photo2)hobia and suffusion of conjunctiva. He would lie quietly for a CLINICAL NOTES ON SOME CASES OP CEREBRO-S'PINAL FEVER. 141 few minutes with the eyes nearly closed, and turned away from the light, till another exacerbation would set in, when, with a shriek, he woiild coui])lain of his head. On the loth, he was in a similar condition, and a gag had to be used to administer food and medicine. On the IGth, he was very weak, but still dared anyone to approach him. In addition to the retraction of the head, the spine was now arched forward, and the thighs and legs flexed. On the 17th, a hard, shotty eruption appeared on the arms and legs ; skin cold and pallid. The treatment was then altered, and fifteen grains of the bromide of sodium, ten grains of the hydrate of chloral, and five minims of the ordinary solution of the hydrochlorate of mor])hia were given every four hours, well diluted in water. On the 18th, he was much (piieter, but resists when you attem})t to administer food or medicine. For the following three days he remained in a state of stupor ; skin cold and pallid. During this period, the mixture was administered thrice daily. On the 22nd, he appeared to be able to recognise those around him, but liis hearing was evidently affected. Eruption faded, leaving a slight mottling of the skin ; hypera^sthesia less marked. The treatment was again altered, and eight grains of the iodide of sodium, ten minims of the B.P. solution of the perchloride of mercury, and five minims of the compound tincture of cinchona was given, Avell diluted in water, three times a day. He steadily improved from the 22nd till the 28tli May, 1887, when he again comjilained of a severe pain in the head and back of the neck, l)ut the symptoms were quickly relieved by the administration of the bromide of sodium mixture, given three or four times. On the 30th, he was quite free from pain, and from this date onward the im])rovement was permanent, and I last saw him on June 12th, 1887, when he seemed quite recovered from the eftects of his illness. Case III. This was a young unmarried woman, of fine j)hysique and good family history. She had been feeling out of sorts for seven or eight days, but able to perform her usual domestic duties. On the evening of the 19tli July, 1887, I was hastily summoned to visit her. While attending to the household work, she was suddenly seized with an attack of vomiting, intense pain in the head, and aches all over. The face was flushed, the tongue whitish, large, and flabby ; the conjunctiva red and suffused, with photophobia ; and the head thrown back. The temperature in the axilla was lOU'F., and the pulse 84. Treatment.— For the cerebral symptoms, forty-five grains of the bromide of sodium, combined with thirty minims of the compound tincture of cinchona, was given eveiy four hours, well diluted in water. The vomiting was checked by giving thirty grains of the snbnitrate of bismuth in milk every two hours ; and the i)atient's strength maintained by administering a dessertspoonful of brandy in water every four hours ; the diet restricted to boiled milk. The room was darkened, all noise excluded, and the patient kept thoroughly quiet. On the following day, the temperature was 99' F., pulse 82 ; and I was informed that she had been delirious all night, but since morning 142 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. had been quieter, with hicid intervals. When conscious, she was extremely irritable, and complained of pain in the head, back of the neck, and on movement along the spine. Muco-purulent discharge from both eyes, lids tumefied, cornea clouded, and considerable uterine liajmorrhage. At 1 1 p.m. a sleejiing draught containing thirty grains of the hydrate of chloral, thirty minims of the ordinary solution of morphia, and five minims of the tincture of digitalis was administered. On the 21st, the temperature was 100° F,, pulse 80. She had slept quietly till 2 a.m., was then very restless; cutaneous hyperesthesia more marked over the region of the heart ; uterine haemorrhage still continued. On the 22nd, she slept till 5 a.m. Three dark-red irregular-shaped purpuric patches along the spine, in the dorso-lumbar region ; uterine haemorrhage less profuse. Now lies in a state of stupor, with head retracted, and thighs and legs flexed. She remained in this state till the 25th, at times becoming delirious, and with difficulty kept in bed, and then again relapsing into a state of stupor. Treatment continued, with the evening draught omitted. On the 26th, the temperature was 98° F., pulse 64, and she could then recognise those around her, but was very irritable and weak ; purpuric j^atches faded, hypera^sthesia of skin and hypertemia of conjunctiva disappearing. Prescribed twenty grains of the iodide of sodium, ten grains of the bromide of sodium, and twenty minims of the compound tincture of cinchona; to be given thrice daily, well diluted in water. At 11 ]).m. a draught was given for three nights, containing thirty grains of the liydrate of chloral, and twenty minims of the ordinary solution of the hydrochlorate of moi'phia. Very slowly, but steadily, the patient improved in health, making an uninterrupted recovery, and by the 18th of the following August, was so far convalescent as to stand the strain of being removed to another part of the colony for a change. Case IV. Was that of a strong, robust young man, 21 years of age, a brother of the young woman, the history of whose illness I have just related. This case presented features of unusual interest to me, as I was present when he arrived home, to all api)earance with the picture of robust health ; and within three hours I was called to see him, to find him in a condition of extreme danger. He had been employed on a station, seventeen miles distant, and, hearing of his sister's illness, he rode over on the evening of the 26th August, 1887, feeling in the best of health. Two hours after, he was suddenly seized with diarrha>a, pain in the head, back of the neck, si>ine, and lower extremities. The greater part of the time he had spent in his sister's room, the curtains of the bed were drawn close to exclude the light, and he had been caressing and hovering over her a good deal. Before I arrived, he had been rcuKned to another house, a little way distant. He was then in a state of collapse, skin cold and clammy ; temperature 96° F., pulse 48, pupils dilated, the head thrown back, the spine arched forward, the thighs and legs flexed, with considerable rigidity of the limbs. He complained of pain in the back of the neck, CLIXICAL NOTES OX SOME CASES OF CEREBUO-SPIXAL FEVER. 143 iind, when the pain in the head became agonising, he woxiUl scream, " Oh ! my head !" The jiaroxysm would last two or three minutes and then abate, when he would lie and moan. Treat ineni. — The diarrhtea was controlled by a mixture containing bismuth, diluted sulphuric acid and morphia. For the cerebral and spinal s\ m]>toms, forty-live grains of the bromide of sodium, coml)ined with ten minims of the tincture of digitalis, were given, well diluted in water, every four hours, and a tablespoonful of brandy in water thrice daih". The room was darkened, all noise excluded, and the patient restricted to a diet of boiled milk. On the 27th, the })ain in the head was greatly relieved ; complained of pain in the back of the neck, and, on movement, along the s[)ine. Photophobia and suffusion of conjunctiva ; hypertesthesia of skin, more marked over the cardiac region ; temperature 98° F., pulse 60. On the 2Sth, I was told that he had been delirious all night. Com- l)lained of pain in the back of the neck and limbs. Photophobia and hyi)en>?sthesia still present. The temperature was 98-6'^ F., pulse GO. Prescribed sleejiing draught, containing chloral and morphine. On the 29th, he had slept till G a.m., quiet and apathetic; tempera- ture 98'G° F., pulse 54. On August 1st, he com[)lained of })ain only on moving ; temperature 98° F,, pulse 50. On August 2nd, the pulse was 54, and on the 3rd was 60. On the 4th, a petechial rash appeared all over the body, with the exception of the liead, hands and feet ; and on the forearms a few whitish, raised spots, feeling hard and sliotty ; temperature 98° F., pulse 60. This eruption remained till the 6th, then disajipeared within 24 hours. Prescribed thirty grains of the iodide of sodium, ten grains of the bromide of sodium, and five minims of the tincture of digitalis, to V)e given thrice daily, well diluted in water. From this time onward, he rapidly increased in strength, and was sufficiently recovered by the end of the month to perform light work. Case V. Was that of a young woman, 27 }ears of age, who consulted me on the evening of the 20th December, 1888. She had always enjoyed fair health, although never robust. On the })revious day, she was suddenly seized with chills, vomiting and diarrhoea, severe lieadache, pain along the spine, which was aggravated on movement, and aches all over ; so much so, that she said she could hardly bear her clothes to touch her. The temperature was 99° F. ; pulse 110; the tongue large and wliitish. T'reatment. — Picst and quietness was advised, and thirty grains of tlie bromide of sodium, combined with ten grains of antipyrin, were given, well diluted in water, thrice daily. On the 21st, the i)ain had nearly disappeared. The administration of the mixture was followed by free diajihoresis, and she is now slowly recovering from the extreme prostration produced by the illness. PiEMARKS. The last case may be cited as an example of a large number that have occiu-red in my practice during the last fifteen months ; and I consider they may be properly classified as aborted cases of cerebro-spinal fever. 144 IXTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. The symptoms, as they appeared during tlie i)rogress of the disease, may be briefly summarised as follows ; — There is the sudden invasion, intense pain in the head and back of the neck, generally I'adiating along the spine, and sometimes into the limbs. The headache is constant, and greatly aggravated by light, sound, or movement, whether active or passive. Then there is a chill, almost immediately followed by retching and vomiting. The tongue is large, white and flabby, later beconung brown ; then, in serious or lingering cases, becoming swollen and black ; the temperature in the early stage rising to 102° F., and in a day or two falling and remaining below the normal till convalescence sets in. The pulse and respiration varied considerably in most of the cases. Delirium sometimes violent in character, and iisually eventuating in stupor or coma. Tonic contraction of the muscles of the neck and back. Hypera^sthesia of skin, generally more marked over the cardiac and epigastric regions. A hard, shotty eruption on arms and legs, only extending as high as the elbows and knees, accompanied later on by a dusky mottling of the skin over the same extent of surface. More rarely cutaneous and uterine haemorrhages. In one case, a })etechial rash ajipeared over the whole body, with the exception of the head, hands and feet. Neuralgic pains in thoracic and abdominal cavities. In every case, there was great prostration. The treatment adopted, I have already related to you. In future, I would feel inclined to scimulate more freely from the commencement of the attack, and I believe more favourable results will be obtained. As to the cause or origin of the disease, I have no new theory to advance. Wheu the first cases came under my observation, I was led to think that inferior flour had something to do with its causation ; as, on enquiry, I found that a considerable number of those attacked obtained their bread from the one Ijaker ; but when we consider that in almost every case, only one meniber of a family was attacked, we must grant that this hypothesis is untenable. On the same grounds, we must exclude the water supply. In many of the cases, the dwellings and drainage were far from being models of sanitary science ; but, in others, little fault could be found with the surroundings. ON SOME FOEMS OF SUNSTROKE OBSERVED IN CHILDREN. By W. K. MacRoberts, jM.B., L.K.Q.C.P.I., Newcastle, N.S.W. Late Physician to the Weutworth District Hospital. The sul)ject of sunstroke — insolatio — heat apoplexy, ])ure and simjile, lias always appeared to me to be peculiarly adapted for investigation by Australian enquirers. So far, the authorities have been Indian entirely. They have conjectured an etiology, including so many predisposing causes, that obtain very rarely, if at all, in these colonies, and least of all in the districts where sunstroke most prevails. The very complete .symptomatology of the disease, contributed by Fayrer, MacLean, and Moore, shows a type, materially different from the Australian type, at least as far as my experience goes. And this has been borne home to me, SOME FOKMS OF SUX.STKOKE OBSERVED IN CIIILDKEN. 145 when seeking guidance iVom their works in many a perjilexing case. As for the pathology, wliioh shonkl be the ultimate criterion of difference or identity, it is, so far, so A^ague and unsatisfactory, that a German observer, Arndt, discounts all the results of the Anglo-Indians, by the tlieory that their post-mortem manipulations were unskilful — " a con- clusion not very complimentary," as Dr. Moore observes. Now, it seems to me that there are many good j^rimd facie reasons, not only for variations of the Australian from the Intlian type, but also for essential ditierences between them. Diversity of race, diet, and modes of life; the omni[)resence of malaria in the one country, and its almost total absence in the other, occur at once, on reflection. The number of predisposing causes enumerated as factors in India, as well as the nuniljer of varieties of the atfection described, lend colour to the suspicion that many other febrile disturbances simulate, and some- times actually "personate" — if I may use the term — the true cases of sunstroke. Nay, it is admitted by the authors, that this is jirobably often the case ; and Hilton Fagge i-emarks, " I should imagine that a person, attacked on a very hot day in India with cerebral haemorrhage or embolism, would lie exceedingly likely to have his case set down as one of " insolatio," even by competent observers." Of counse, it is quite jjossible for mistakes in diagnosis, or confusion of types to occur here as well ; but I w^ould submit, that the chances of other morbific influences intervening " to darken judgment," are not nearly so many. In the flrst place, the reputation uf the Kiverina district for instance, which I take as the Australian type for salubrity, is a great contrast to the '" bad eminence " of Bengal, in the opposite particular. Population is extremely scanty, there is no overcrowding, and epidemics are, therefore, few and far between. Malaria is absent, and the eucalyptus trees shed forth one nevei-failing antiseptic effluence in the bright dry aii". When sunstroke occurs, it is sunstroke, a veritable ictus so/is, from — " The stress of tlie noontide — those sunbeams like swords!" The stroke is swift and sudden and obvious, and jiredisposing causes obtrude themselves very little on our notice. For these and other reasons, I am inclined to think that the class of nervous affection, due to the action of excessive solar heat in the colonies, is more distinct, more clearly defined, and separate from extraneous confusing influences, and, therefore, more open to accurate scientific investigation, than the varieties hitherto descriVied and investi- gated by the Anglo-Indian writers. It is, however, in dealing with cases of sunstroke, in which the sufferers are children, that the classical descriptions of the disease appear most inapplicable. During the three hottest months of the summer of 87-88, in Wentworth, in the Riverina, I encountered a series of at least a dozen cases, in which the patients' ages varied from two years to twelve. In no case was there room for doubt that the action of the sun's rays was the actual ccmsa causans, though hygienic and jjhysiological conditions undoubtedly caused variations in the train of .symptoms. The variations, though great in degree, were engrafted wpon a distinct and peculiar type— a type very inadequately designated by the appellations of sun fever, ardent fever, or thermal L 146 INTERCOLONIAL MEDICAL COXGRESS OF AUSTRALASIA. fever, and not to be accounted for on Murcliison's theory of all the milder varieties of sunstroke being sini])ly cases of intermittent fever. It would rather appear that the undeveloped, or only developing, motor and special sense cerebral centres of children yield a different note to the stroke of the sun from that of adults. That the action upon them is at once more intense and more diffuse, as well as more lasting, as will be seen from a recapitulation of a selection of the cases. They followed each other with such rapidity in the very hot weather, as to suggest at first the advent of an epidemic of typhus, typlioid, or cerebro-spinal fever. However, I was able in each case to trace a history of prolonged exposure to the sun, preceding the onset of the S3anptoms. In fact, the sudden seizure after exposure was the only prominent featiire the cases presented in common. Intense cephalic pain was also present in all, and, in the fatal cases, coma preceded death. For the rest, as will be seen in the detail of the cases, the symptoms varied on an ascending scale : — Severe pain, with constipation and delirium at night ; cephalic j^ain, with cerebral vomiting ; pain, with convulsions ; pain, with asphasia and non-spastic hemiplegia ; intense j^ain, with spastic hemiplegia. Case I. — 11. P., ?et. .5, presented a history of exposure to a hot sun, without a hat, at a children's picnic. There followed immediately an attack of cerebral vomiting, and severe occipital pain, and most obstinate constipation, which continued all through tlie illness, though previously the bowels had been free and regulai'. There was also considerable delirium at night, and temperature lemained at 100° for four days. Belief was afforded by te})id sponging, K. Br. in large doses, and the use of injections. Recovery in about ten days. Case II. — A. M., jet. 3, lived in the bush, exposed to afternoon sun, and woke up in the morning with all the symptoms of infantile paralysis. On examination, I found great loss of })Ower in lower extremities, tenderness in legs, and all along the s})ine, on pressure ; slight retraction of head, and complaint of pain in nape of neck. Temperature 102° Fahr. Treated with strong counter-irritants along spine, blister to occiput, followed by small doses of quinine. All the symptoms disappeared in three days; but three weeks after this, there was, unfortunately, another long exposure to the hot sun, an attack of A'orniting, followed by convulsions, coma, and death. Case III.— D. M'L., jet. 10, a child of full habit of body. History of violent exertion — running up a hill on a hot day wdth hat off. A sudden attack of com])lete aphasia and right hemiplegia, which lasted seven days, and then began to disappear together. Treatment consisted in rest in dark room ; blister over left half of cranium ; calomel in yVS^'^^"^ doses every quarter of an hour, and gr. x of K. Br. at night. Improve- ment began on the eighth day, and under quinine, strychnine, and Faradism, a complete cure was efiected in 36 days. Cases IV. and V. — Two children — sisters — jet. 4 and 5 respectively, were suddenly attacked together with occipital pain and convulsions, after wading in the river on a hot day. These cases ran a very rapid course, death occurring on the fourth and fifth days, after convulsions and coma. Calomel was given, as in Case III. The wet pack was tried, and in each case brought dovvn the temperature from 104° to 103° Fahr. on the first application, and after that had no effect. I SOME FOUMS OF SUNSTROKE OBSERVED IX CHILDREN. 147 Case VI. — S. B., jet. 12, a resident at the irrigation colony of Mildura, then in a very primitive state. She had been living in a tent, and seems to have been badly nourished. She was decidedly overgrown ; had been ailing with headache and feverishness for some days before I saw her, after exposure to great heat. Having been consulted by her father, I advised a continuous wet pack, which was not applied. She was admitted to hospital subsequently in a hopeless condition ; tempera- ture, 107\ Convulsions every five minutes, and between the fits x'igid contraction of the muscles of the right side of the body. Intervals of semi-consciousness, during which intense cephalic pain was evidently present ; contracted ]iupils. Wet packing tried, and reduced temperature 2" Fahr., but only temporarily. Kectal irrigation with cold water also tried, with no etFect. Counter-irritants were also ineffectual. Coma supervened, and then deatli, in twenty-four hours after admission. Such are the six cases I desire to present to your notice. I had others, probably of the same nature, but I have omitted them, because the history of exposure before the attack was not so clear and unmistakable as in these. The cases unfortunately lack the essential interest of a post-mortem; but the train of symptoms following a sunstroke are sufficiently striking to draw attention to them. They present few points of similarity to any of the varieties of insolatio in adults. The convulsive and paralytic notes are here the dominant ones. A comparative i>hysiology of children is wanted, to show how and to what extent their heat-regulating and vaso-niotor centres react to external impulse. Roughly speaking, I should say that the heat- regulating centre of Naunyn, Quincke, and Ott was, in these cases, directly and powerfully affected ; and that simultaneously other centres lying in close proximity, and probably less disconnected from, and independent of it, than in the adult, were excited to discharge their influences by the same cause. Kussmaul and Tenner vouch for the existence of a spasm centre, at the junction of pons and medulla, extremely sensitive to the action of venalised blood, and to direct stimulation of any sort. The action of a temperature of, say 110° Fahr. in the shade, through the delicate cranium of a young child, upon its cerebral vessels, would certainly amount to direct stimulation of a good many cortical centres, and even medullary tissues. It is to this direct action, rather than to that of venalised blood, I am inclined to ascribe these cases ; and it is to some therapeutical method, promptl}' directed to the heat-regulating centre, I would look for success in treatment. As will have been seen, my treatment was empirical, and only moderately successful, for want of reliable authorities to look to for guidance. It was only in my last case (Case YI.) that I came, as I believe, on the right track, and then it was too late. Even at the eleventh hour, however, a 12-grain dose of antipyrin produced a fall of 2° Fahr., and a slight and momentary cessation of symptoms. The earliest and the latest experiments upon the action of this invaluable drug, alike point to the conclusion, that its action is dii'cctly upon the heat-producing centre in tlie corpora quadrigemina. Anyone who has made much use of it, be he a physiologist or not, must come to the conclusion that it goes straight to head quarters, wherever they may be, and does its work with l>usiness-like jjromptitude. Here we have, I should think, the true and reliable remedy ; and, except where heart failure is threatened, I now 148 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. commence the treatment of any case presenting febrile and cerebi'al symptoms combined, with an appropriate dose of antipyrin, by this means, I consider, obtaining a decided vantage ground at the start, as its action is as certain as clockwork. However, here I leave my cases to your consideration, and earnestly invite discussion and further investigation by Australian practitioners of this peculiai'ly Austi-alian subject. As a lethal agency among the children of our imperfectly acclimatised race in the hot districts of this continent, I am confident that sunstroke in some form or other is almost supreme. No effort has yet been made to follow the obviously useful hygienic example of the Chinese and Hindoos, who shave their heads, and by the iise of fans producing a cool current of air, can walk about uncovered under the hottest sun. At any rate, European parents who, in tera])eratures ranging to 110° in the shade, allow their children to go about with heavy hats and long thick curls, may pei-haps soon learn from the indigenous Asiatics, that safety lies in the opposite direction. "Sun-bonnets," with which little girls are particularly liable to be afflicted, are, I think, most objectionable. The best form is a light, well-ventilated straw hat, which should serve until we reach, in process of evolution, the shaven crown and palmetto fan. Why, too, our children in the Riverina district are expected to sit in school all the hot summer after- noon, and return home sometimes long distances at the very hottest period of the day, while their little Anglo-Indian cousins think of nothing but siesta after twelve o'clock till the evening cool, it is hard to understand. At any rate, they are expected to do it, and this tyjie of disease is one of the outcomes of the system. Acclimatisation is going on, and it will not be entirely accomplished in one generation. As it is, I have noticed a remarkable difference in the capacity for standing heat between the children of Europeans and those of the colonial born, while Chinese half-breeds seem to enjoy a happy immunity from adverse solar influences. And here, perhaps, arises another question within the Chinese problem, for the number of children of Chinese fathers and European mothers already bears a high })roportion to the total juvenile population in and around Wentworth, and I believe in AVilcannia also ; whether they may not prove the " fittest " in the hard struggle for existence in those districts, is an open but alarming question. As an appendix to these notes, I would call attention, if it has not already been done, to the great prevalence of a form of occipital head- ache among adults in the Wentworth tlistriot. It is always regarded by the sufferer as the remains of a "touch of the sun," and seems to be really due to a congested condition of the occipital dura mater. It is relieved by leeching over the sinuses ; and, by a long course of iodide of potassium, is usually permanently cured. Sometimes intense i)ain is complained of in this region, and in such a case, I have always found tinct. cannabis indica^, in 30 minim doses, a certain means of relief. mSTOKY OF TYPHOID FKVER IX VICTORIA, AND ITS ETIOLOGY. 149 TYPHOID FEVER. A General Meeting of the Congress was held in the Wilson Hall on Friday, January 11th, 1889, at 2 p.m., the Honourable Dr. Taylor, President of the Section of Medicine, occupying the chair. The following papers were submitted concerning the history, etiology, ]>athology and treatment of typhoid fever. A discussion followed, which, on account of the limited time available, was restricted to the subject of etiology. HISTORY OF TYPHOID FEVER IN VICTORIA, AND ITS ETIOLOGY. By James Robertson, M.A., M.D. rormerly Physician to the Melbourne Hospital, and Lecturer ou Medicine in the University of Melbourne. It will be readily allowed that typhoid fever is now endemic in Victoria, and, I believe, throughout the Australian Colonies. The ^[uestion naturally arises — is it identical with the form of fever formerly (lesignated " Colonial 1 " In answering this question, I avail myself of such information as is supplied by the writings of pioneer members of our profession. In the early days of the colony, prior to the discovery of gold, the prevailing fever was regarded as incidental to the climate, a seasoning fever, and was thence designated "Colonial." Colonial fever was described by one of the early medical pioneers (the late Dr. David John Thomas), as " bilious remittent," with typhoid symptoms, having no regular period of incubation, and running no regular course, but usually terminating in a critical discharge of dark-coloured bilious offensive matter. The name " bilious remittent " suggests the idea that the so-called •' Colonial fever" may have been due to malarial poison, emanating from marshy or swampy soil, and its being regarded as a seasoning fever tends to foster that idea. That such was not the case, however, may be legitimately inferred from the absence of any form of inter- mittent or malarial fever, originating in the Colony of Victoria. Dr. Thomas afterwards stated that, on resuming practice in 1860, after a prolonged visit to Eui'ope, he had not seen a genuine case of the old Colonial fever, and that typhoid seemed to have taken its place. The fever, prevalent on the diggings in 1854 and 1855, was described by another writer in the Australian Medical Journal (Dr. Hunt), as "fever associated with dysentery, not of the ordinary inflannnatory type, but of a hsemorrhagic character — fever of the typhoid kind, which assumed a less severe aspect, with the gradually ameliorating circumstances of the digger's life." My own recollection of the fever prevalent in Melboui-ne, extends to the year 1853. It was certainly of a very low type, and not infrequently attended with haemorrhage from the bowels, a feature which stamped it as being true typhoid. The term " remittent " was doubtless used as 150 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. expressing the more obvious symptoms, the occurrence of exacerbations and remissions, for in those clays the temperature was not tested by the thermometer. Typhoid often assumes a distinctly remittent form, in which the evenino- exacerbations and mornincj remissions are well marked. A case of fever is reported in the Australian Medical .Journal, January 1856, xmder the heading, ''Autumnal Fever," by the late Dr. Tracy. From the symptoms described — " tenderness in the right inguinal region, hpemorrhage from the bowels"-— it was evidently a case of typhoid fever. According to Dr. Thomas, typhoid first appeared in the colony in 1842, being introduced by the ship Salsette. Three men from that vessel were engaged as farm labourers at Heidelbei-g, and were attacked by the fever. It proved fatal to two of them, and spread as from a centre, attacking others in the neighbourhood. Other immigrants from the same vessel, who went into the bush, were similarly attacked, and communicated the disease to others. I would observe that in 1842 the distinctive characteristics of typhus and of typhoid had not then been recognised. They were regarded as identical in their nature, mere varieties, due to the action of the same specific poison. Jenner had not then shed a light on their obscure relations. From the highly contagious character of the fever described, it may also be surmised that the form of fever was typhiis, not typhoid. Typhus is found to be eminently contagious, and to spread directly from the sick to the healthy, while cases of typhoid may be treated in the wards of a general hospital, without the disease spreading to the patients in the adjoining beds. Prior to the year lS60, the fevers i)revalent in Victoria were known or described under various terms, such as " Colonial," " continued," "low," "bilious," "remittent," "bilious remittent" and "gastric." The variety of names arose, no doubt, from the sudden influx of medical men during the early period of the Victorian golden era, and the employment by them of such terms as they considered best descriptive of the nature of the fever met with. (_)n my appointment as Physician to the Melbourne Hospital in 1 860, I employed the opportunities presented, and found that the autopsies in all fatal cases of fever revealed the same anatomical signs, according to the stage of the disease. The tumefaction and ulceration of Peyer's patches, and of the solitary glands, were found to be well marked in the lower part of the ileum, particularly in the neighbourhood of the ileo-ca?cal valve. Cases of fever were found to vary much in regard to severity and duration, some being comparatively mild, and others very se\'ere and protracted. The temperature was not always characteristic, the abdominal and intestinal symptoms varied, the rose-coloured spots and diarrhcea were often absent ; yet, when opportunity offered in cases proving fatal by some complication, the intestinal lesions served to confirm the true nature of the fever. Before commencing to write a course of lectures on fever (in 1864) for the Medical Students of the University, I had assured myself that, however the fever might vary as regards its symptoms, severity and duration, and by whatever names it might be designated, it was essentially the same in type ; being, in fact, the true typhoid or enteric fever so prevalent in Europe, HISTORY OF TYPHOID FEVER IX VICTORIA, AND ITS ETIOLOGY. 151 Ffoui tlie evidence adduced by Dr. William Budd, of Bristol, England, and by other.s, I had also arrived at the oiiinion that it was connnuni- cated by contagion. On referring to my notes, written at that time on the causation of the fever, the first sentence runs thus : — " The weiglit of evidence unmistakably proves, not only that this disease is contagious, but that it is now only projiagated l)y contagion." There is no reason to supj)0se that it was generated here, or that it existed among the aborigines. Their nomadic habits would, I believe, preclude its existence. Typhoid fever has, at various periods within my own knowledge, been imported into the Colony from British ports, and the conclusion may be legitimately arrived at that it was originally so introduced, ancl had become endemic at a very early period. Soon after the year 1860, the nomenclature of fevei's gradually underwent a change, and the term " Colonial " was supplanted by "typhoid" or "enteric." In a letter under the heading "Hospital Mortality," published in the February number of the Australian Medical Journal, 1865, I wrote as follows: — -" The statistics of the Melbourne Hospital are compiled by the Superintendent, and in classifying diseases, he is guided by the Nosological Table published by the Registrar General of the Colony, which certainly requires emendation before the fever statistics can be employed as reliable data for the purpose of comparison. The nomenclature adopted is faulty." All fevers were then classified under two heads or forms — I. " Typhus and Infantile Fever ;" II. "Remittent Fever." I further noticed "that no case of typhus, of infantile, or of remittent fever, came under my care during 1863. The type of fever prevailing then was typhoid, as it is now" (1865). In the August number of the Australian Medical Journal, 1867, is to be found a carefully- written jiaper by Dr. MacGillivray, of Sandhurst, " On cases of Fever occurring in the Bendigo Hospital," with statistics and temperatui'e-charts. He there states : — " An opinion is held by some practitioners that, as well as enteric fever, we have here also a bilious remittent, to which the name of ' Colonial ' is applied. So far as my experience goes, I can only say that I have never seen such a fever here." There is now a general consensus of opinion, that typhoid is the prevailing form of fever met with in this Colony. The history of typhoid in A'^ictoria differs but little, if at all, from the record of that disease in the other colonies, or in other countries. It prevails at certain seasons and in certain localities, influenced by filthy and unwholesome surroundings, but more esj)ecially by emanations from decomj)Osirig excreta of typhoid patients. It varies from year to year, as regards frequency and fatality, owing to meteorological changes, a mild winter and moist autumn betokening a severe ty|)hoid season. A reference to the tables of mortality issued by the Government Statist shows that, while phthhsis is the first of all diseases in causation of fatality, typhoid fever occupies the eighth ])hice. The annual mortality from typhoid in Victoria has varied from 3*49 to 7-26 per 10,000 persons living, during the period extending from 1873 to 1886 inclusive (l-t years), the average being 5-23, exactly that of New South Wales. In Queensland, the death-rate from typhoid is much above that in Victoria ; while in South Australia, Tasmania, and 152 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. New Zealand, it is lower ; and in England and Wales still lower, in the five years ending with 1886. The mortality from typhoid in England and Wales has been reduced from 4'30 to 249, and this has been brought about by the adoption of general hygienic measures. The adoption of similar measures in Yictoria would, without doubt, be attended by equally beneficial results. Etiology of Typhoid Feyer. Typhoid is without doubt contagious, but not in the same way, or to the same extent as typhus, small-pox, measles, or scarlatina. These are highly contagious, and are readily conveyed from the sick to the healthy, within a very limited area, at all times, and I might almost add, at all seasons of the year, Avhen immunity is not conferred by a ])revious attack. They are apparently conye3'ed by emanations or exhalations from the bodies of the sick. It is not so with typhoid. Seldom, if ever, is it communicated directly to patients in the adjoining beds in the wards of a general hospital. The conditions which tend to its spread are doubtful, or not yet fully understood. It is not conveyed im- mediately from the sick to the healthy. The exhalations from the lungs and skin, and even from the fresh discharges from the bowels, are only yery slightly, if at all, contagious, otherwise more direct and satisfactory evidence of contagion would be available, such as is found in typhus fever, itc. Fresh or recent typhoid dejections are not regarded as con- tagious, but become so by exposure, or during the process of j^utrefac- tion, or fermentation. In proof of the innocuous character of fresh typhoid dejections, I may notice the fact, on the authority of Murchison, that the disease was not ti-ansmitted by feeding a pig on such dejecta, mixed with barley meal ; on the contrary, the pig throve and waxed fat. It is otherwise, when pigs are fed with tubercular matter, or milk from tuberculous cows — they are said to fall victims to tuberculosis. Although fresh typhoid eyacuations are not considered contagious, the exhalations from privies, cessj)Ools, di-ains, and sewers, to which the discharges from typhoid patients have found access, are regarded as highly contagious. It has been found that water, from wells contaminated by percolation from such sources, has proved the carrier of contagion. Milk appears to have some special atfinity for the contagion of typhoid, and to prove a very suitable medium for spreading the disease. It is now generally accejited as proved, that contagious diseases ai-e caused by the introduction of certain specific organisms or microbes into the bodies of those susceptible of contagion. Bacilli have been detected by so many observers in typhoid cases, that their presence is now assured. They are found in the intestinal canal, in the lymphatics, mesenteric glands, spleen, liver, kidneys, ifec, in small masses. They have been cultivated external to the body in stiff' gelatine, but are confined to the spots where they have been implanted. A very important question still awaits solution — Have bacilli an in- dependent existence external to the body 1 They are said to form spores at certain high temperatures (86° to 108° Fahr.) It may therefore be reasonably supposed that they meet with conditions favourable to their development in warm climates, and this may account for the prevalence of typhoid in warm countries. HISTORY OF TYPHOID FEVER IX VICTORIA, AXD ITS ETIOLOGY. 153 It is only under certain conilitions or circumstances tliat typhoid appears to be transmissible. What are the conditions, local and personal, that induce typhoid? There is, it appears, a local or endemic influence, called into action more e.specially at a particular season of the year, and also a constitutional factoi', rendering some more susceptil)le than others. Ill this colony, typhoid is more rife in the autumn months, in that respect corresponding with that prevalent in Europ)e. In winter, with a low temperature, it is absent; on the return of summei', sporadic cases occur and become more and more numerous on the approach of autumn. It is about the end of autumn that the fever becomes most prevalent, particularly during the months of March,, April, and May. The number of cases appears to be diminished in dry hot weather, and increased by heat and moisture. I have observed that after a rain-fall, cases of typhoid become more numerous. The contagia, be they bacilli or spores, then meet with certain conditions that render them active, or tend to their growth and multiplication. The season, favouring decay and putrefactive changes, is that in which typhoid flourishes. Statistics prove that lieat and moisture combined are followed by an increase of fever. A tabular statement of climatic conditions, compiled by Mr. C. Moerlin, at the Melbourne Observatory, compared with one showing the number of deaths from typhoid prepared by the Government Statist, ])ublished by the late William Thomson, F.R.C.S., in his work on Typhoid Fever 1878, proves that the deaths from typhoid fever were especially numerous in the months of Mai'ch, April, and May, from the year 1874 to 1878, inclusive, more so in those months when rain had fallen copiously. In making this observation, I am aware that the con- clusion arrived at is somewhat at variance with that drawn by the author from the same data. The figures admit of the inference that warm damj) weather contributed to an increase of the number of cases of typhoid fever, or at all events, to an increase of the number of deaths from that disease. Many years ago, I expi-essed the opinion " that the frequent occurrence of typhoid fever in the autumn season, was mainly attributable to the facts, that heat and moisture favoured putrefaction, and that the atmos- phere thereby became impregnated with emanations from decomposing excreta." This view would be more in accordance ^yith the advanced pathology of the pi'esent day. if the word '' bacilli" was substituted for " emanations." Outbi-eaks of typhoid fever have not infrequently followed the open- ing up of offensive drains ; but all exposed to the exhalations have not Vjecome the victims of fever. This brings me to notice the pt'sonal or constitutional factor in causation. Assuming that bacilli are extensively scattered over a large area, or rather areas, in the typhoid season, as only a few persons become affected, it is evident that some predisposing cause or causes are in operation. For the germination and growth of a plant, we know that not only is the gei-m or seed necessary, but the soil tit for its reception, and other conditions, as regards tem])erature, moisture, tfec. We have found that the season of the year greatly influences the prevalence of fever. We find also that certain localities are more 154 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. particularly liable to its invasion, owing to local insanitary conditions. Whether these conditions operate by favouring the growth, multiplica- tion, and greater activity of the bacilli, or by impairing the bodily health, and inducing some personal or constitutional susceptibility, are questions yet to be determined. Age, without doubt, is a predisposing cause of typhoid fever ; children under one year do not appear to be liable to it, and even under five they do not readily contract it. From five to ten, and from ten to twenty, the fever becomes more and more i^revalent with advancing years ; it reaches its climax, in point of frequency and severity, at adult age, and does not greatly decrease until after the age of thirty. It is a remark- able fact, that delicate persons are not so liable to fall victims to it as the apparently vigorous. One attack of the fever gives immunity to another, as a rule; typhoid, in this respect, following the general law of eruptive fevers. This may explain, to some extent, the less frequency of its occurrence in advanced years, many having passed through the fever in early life. How far the changes that take place in Peyer's glands may contribute to that exemption, is a subject for inquiry. What constitutes the personal or constitutional predisposition to fever? This is a point to be solved, nodus vindice dignus. It may be argued that the bodily functions have become impaired by the prolonged heat of summer — digestion, assimilation, and nutrition being rendered imperfect, and secretion and excretion defective ; that effete products have thus accumulated in the blood ; that vitality has been lowered, so that the system is less able to resist the attacks of bacilli. The increased susceptibility incident to adult age, may be accounted for by the active exertion, consequent on tlie daily duties of life, occasioning more tear and wear of the system, and thus increasing the effete products in the blood. Again, it may be assumed that there is present in the system some suitable jiabulum that affoi'ds support to bacilli, or ministers to their germination, growth, and multii)lication, the presence of this pabulum constituting the determining, or immediately predisposing, cause of the disease. On this supposition, the mildness or severity of a case of fever might be accounted for hy the amount of pabulum present in the blood ; should the amount be small, it would speedily become exhausted by bacilli, which would then perish, and become eliminated from the body. How do bacilli gain access to the body 1 Are they inhaled ; or are they swallowed with food and drink ? It is believed that they are generally conveyed through the medium of food and drink ; that they are taken into the stomach, and pass into the small intestine, where they are supposed to meet with conditions favourable for their growth. They are said to penetrate Peyer's glands, the mucous follicles, and lymphatics, and thus gain access to the blood, where, it is presumed, they grow and multiply. Their ])resence in the blood is, however, not well assured ; and in that respect, the bacilli of typhoid conform to the behaviour of the bacilli of tuberculosis, whicli are not, as a rule, observed in the blood, but are found in different tissues and organs of the body. THE ETIOLOGY OF TYPHOID. 155 THE ETIOLOGY OF TYPHOID By J. G. Carstairs, M.D. Not so many years ago, it appeared as if the genu theory of typhoid, evolved by the genius of Budd, would shortly become the universally accepted belief of the profession. From some cause or another, the progress of that theory received a check; and now, up to the year that has just closed, with one exception, all recent English writers on fevers regard typhoid through pythogenic media. However, as they have abandoned the doctrine of the generation of the poison de nooo, and acce])ted the belief that the contagium is truly specific, and always derived from previous cases of the disease, the point at issue is virtually settled in favour of the germ theory, and Budd's views are vindicated. This forms my starting point. By common consent, typhoid is admitted to be the result of the entrance into the body of a specific living contagium, always derived directly or indirectly from previous cases, which multiplies in the body, flows in the blood, permeates all the tissues, and is thrown oft' from the body to propagate itself afre.sh in suitable soil. The striking analogy to plant life in the multiplication of the contagium is universally recognised ; and as the processes set uj) by it in the living body are always true to type, the conditions of its existence, growth, and other characteristics must be subject to fixed law. That the contagium lives indefinitely outside the body is indisputable ; that, like other seeds, it lies dormant for a time, requires no proof ; that, like them, it grows and multiplies, in obedience to natural law, is shown, on a large scale, by the periodic annual i-eturn of typhoid; and, on a smaller scale, by the cultivation expeinments of the bacteriologist. But as this last point is an undetermined question with the pythogenic school, and virtually commands the position, let me illustrate it. Germination of the contagium outside of the body. Parenthetically let it be noted, that the average annual mortality for this colony from typhoid is 430, and that of Melbourne 212, or about one-half. From monthly statistics of the mortality in Melbourne, extending over twenty -four years, we learn that the average monthly mortality is at a minimum in November ; thence it increases more or less rapidly, attaining its maximum from March to May. In June there is a sudden fall in the death-rate, which decreases monthly till the minimum is again reached. Now, the mortality in one month must arise largely from those wlio contracted the disease in the previous month, and as the rise in the mortality (consequent on the prevalence of typhoid) commences in December, most of the cases received their contagion in November. The seeds of the contagium, which have lain dormant in the soil and elsewliere during the cold weather, have then begun to germinate in November, and multiply; and the increase of the mortality, amounting to 120 per cent, in December, is at once the result and the proof of their growth and multiplication. When you see a ci^op of thistles growing, you know that the seeds from a i)arent thistle, which have lain dormant in the soil, have germinated ; and when you see a crop of typhoid growing, you know that its seeds have germinated. You did not see the seeds of the 156 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. thistle any more tlian those of the typhoid, but you know the crop would not have appeared if the seeds had not been in the soil, and germinated. The period of the germination of the contagium, therefore, commences in November, and is coincident with a mean tenipei-ature of the air of 60"2°, and of the surface soil of 69"5^. That this is no mere coincidence, is shown by the regularity of the yearly recurrence of typhoid, and further, by the fact that when the temperature in November is above the average, so is the prevalence and mortality in December ; and when the former is below the average, so also is the latter. In other words, the season for typhoid is earlier or later. But the increased mortality in December is only the first fruit of the lethal crop. With the increasing temperature, the rate of multiplication of the germs of contagium increases, and as a consequence, the death-rate, till the maximum is reached in March to May ; after that, the temperature having fallen l)elow that of November, the germination in the open air is arrested. Hence, in June there is a sudden fall in the rate of the mortality, and as in December the rise was shown to be the result and proof of the multiplication of the germs, so in June is the fall the result and proof of its arrest. The specific living contagium of typhoid, therefore, germinates and grows outside the body, in the soil, or where it finds itself; and the condition of its growth and increase is a high temperature, such as we have here from November to April. Gati'ky, in his admirable treatise on "The Etiology of Typhoid," recognising the importance of ascertaining the temperature at which the bacillus of typhoid formed spoi'es, that is, multiplied, made it the subject of careful experiment. The result I give in his own words, only substituting the degrees Fahrenheit for the centigrade scale he uses. He says : — " The temperature most suitable for spore-formation seems to be from 86° to 104°. At 77° it occurs somewhat latei", but still indubitably. The lowest limit seems to be 68°; at least, at this temperature, after eight days' growth, I have only observed a very few, and only moderately developed, spores in the bacilli. After two more days, the process was not much further advanced." Further, Gaft'ky never found the bacilli " become causes of putrefaction, although sown in substances very liable to piitrefy." A certain range of temperature was the sole condition for the sporing of the bacilli ; and so, in the case of the germs, the spores, lying about this city, obedient to the law of their life they germinate, owing neither their evolution, nor their ]J0wer of multiplication, to decomposition going on in organic filth, but to heat alone. And what happens here, will happen all the world over. But here it may be asked, What of those cases of typhoid occurring from June to November "J If germination of the contagium is arrested, why is the disease not arrested also 1 The reply is easy. The disease is largely arrested, as shown by the mortality, and though the germs cannot multiply at the outside temperature, yet they are there, and living ; and as in the summer they find their way into the human body, so they can in winter, and once there, they find the condition and temperature most suitable for their growth. Tills leads to the question of the entrance of the conta(/iiivi into the body. Most recent authorities hold that the contagium finds its way into the TIIK KTIOLOGY OF TYPHOID. 157 living body almost exclusively by the alimentary canal, in water, food milk, ikc. That it enters by the air-passages is admitted as a probability only — a statement of ojunion that recjuires overliauliiig, like many others regarding typhoid. That any article of food or drink containing the tyi)hoid germs does — nay, mnst—oi necessity produce the disease, goes without saying. That widesj)read and limited outbreaks have been traced to contaminated water-supply, is undeniable. But that the annual autumnal prevalence of typhoid, here or anywhere, is due to a regularly automatic pollution of food oi- drink, is neither consistent with observation nor common sense. Therefore, as by far the greater num\)er of cases of typhoid happen during this regularly recurring ])eriod, their contagium does not enter the body by the alimentary canal, and must, therefore, do so by the air-passages. So far, then, from this being a probability only, it is a moral certainty. A word about milk epidemics. I do not mean tlie spurious hypo- thetical, which require such an amount of ingenious reasoning to give them an appearance, and only an ajjpearance, of truth ; but the true milk epidemics, which iiossess one constant characteristic feature, viz., the presence at the farm or dairy of one or several cases of typhoid, the patients being nursed by those who milk the cows and attend to the supply. It is positively painful to read in the accounts of these out- breaks the minuteness of the details about middens, drains, leakv cesspools, and polluted wells, which are presumed to form the chain of connection between the patients and the contaminated milk. It is astonishing to see this roundabout wa}' absorbing all tlie attention of the narrators, while the plain, the direct way, is staring them in the face. Daily, and for weeks together, does the nurse leave the bedside of the fever j)atient to milk the cows ; her clothes and hands are saturated with the poison ; the milk-pail is steadied between the knees, and the fingers are frequently dij^ped into the milk in order to lubricate the teats. Could the milk escape being contaminated ? Long before the drainage from midden or cesspool could percolate to the well, the milk was infected by the hands, and the pail by the clothing of the milkmaid. Says Lawson Tait, " We now know that the raid against lying-in hospitals was a mistake. Destroy the germs on the hands of those who attend parturient women, and the women are safe." Destroy, then, the germs on the hands and clothing of the milkmaid, and the milk is safe. Exit of the contagium from the body. All agree that the contagium leaves the body in the dejections; few admit of its elimination in the breath, or persjnration. The jiythogenic school maintains that the fresh f.eces are innocuous, and devoid of the power of contagion, but that after decomposition, they certainly contain the typhoid poison. In a former portion of this paper, it was shown that the multiplication of the germs outside the body was due to heat alone. The question is not one of acquired virulence, but of inherent life. If the specific contagion, on leaving the body, has lost the power of contagion — that is, of Tnidtiphjing, it is dead ; aiid decomposition, instead of infusing life, will only disintegrate it. xVgain, if decomposed typhoid stools "certainly contain the poison," then of necessity it existed in tiie recent stools, for there is no spontaneous generation. No, the specific cause that has 158 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. wrought such havoc in the human body leaves it a livirKj self -projnt gating thing. But further, a contagium vivum that circulates in the blood, finds itself in the capillaries of the skin, and of all the organs of the body ; and though we admit that its chief outlet is by the bowel, yet we cannot deny its elimination by all the emunctories. I need not remind you that, although the invariable anatomical lesion is situated in the ileum, yet the whole intestinal tract, from pharynx to colon, may be, and often is, the seat of inflammation and ulceration. To refer to the throat affection only, at times so severe as to have been mistaken for diphtheria, and which, if looked for, I fancy would be found more frequent than is generally believed, how will, how can the poison be eliminated but in the breath and sputum 1 and the same may be said of the ulceration of the larynx, the bronchitis, pneumonia and gastritis so often present. And what of the skin, with its extensive drainage surface, does it remain idle in presence of the common enemy? Throwing off, as it does, 80 per cent, of the body heat, and as the smell from its surface indicates the disintegrated products of tissue change, why not the contagium also 1 When the skin acts well in typhoid, the patient does well. It may be said, sweating reduces the temperature. True, but is it not by removing the fuel, the cause of the increased body heat ? This brings me to the question of contagio7i. Not the conimunicability indirect, which is generally admitted, but the direct, from person to person, which most deny. Dr. Collie, of Homerton, is the only recent English writer on fevers who contends, and rightly contends, for direct contagion. If it is admitted that the views above stated are correct, viz., that the poison is eliminated by the lungs and skin, then the acceptance of the belief of direct contagion through their emanations cannot be withheld. The limited time at my disposal forbids the giving the histories of cases in point to support the position — let me but indicate their meaning. A patient is brought from a distance to a locality where there is no fever ; a relative sits by the bedside for a few hours once only ; or another sleeps one night with the patient before the nature of the disease is known ; both fall ill within a fortnight. Now had it been measles or scarlet fever, there would be no hesitation in saying they caught the disease directly from the patient. And when you see typhoid behaving in the same manner, arguing from the general to the particular, you say the same thing has happened — direct contagion. Again, when you find that a child of less susceptible age, who has been in this close contact, takes the disease, while several other members Of the family of a more susceptible age, but who have not been in such close contact, csoapc — taking the positive fact that the less susceptible was attacked, and the negative fact that the more susceptible escaped, and that the only difference in their circumstances was that the one was in close contact, and the otliers not — what is the legitimate inference 1 Is it not, that the contagion distance is short 1 You admit this of typhus, why deny it of typhoid, with whicli it was so long confounded ? The contagion is not of a volatile, diffusive natiire ; it clings to the body and clothing of the patient, it clings to its surroundings, it clings to limited areas of towns. It may be in a drain or dung heap, yet show no sign till the one is stirred up, or the other turned over. 159 * INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. General Sketch of Locality. FITZROY COLLINGWOOD MlLBOURNt Scale, about ^ Inc1}e§ to iffe Tiple TYPHOID FEVKR CON'XECTED ^VITII MIMv SUPPLY. 159 In complete harmony witli this view is the spread of typhoid in rural or thinly-poinilated districts from person to person, and f;imily to faniily — first, to the members of the household to which a fever patient was brought ; then, to the neighbours and friends who Yisit the house, and assist in nursing the ])atients. You have seen this scores of times. The journals here, and in the old country, abound with narratives of such outbreaks. There can be little doubt of direct contagion from all the emanations of the body. To sum up, the contar/iian of ti/phoid grows outside the body, and the condition is a temperature from 70° to 104°. It enters the body largely through the air-])assages. It leaves the body in all the emana- tions, though chiefly in the dejections. It is directly contagious, the contagion distance being short. Though necessarily present in filth, it owes nothing to that, save as ii vehicle. Prevention — destroy the germs outside by improved sanitation. Let not another germ from typhoid patient live. Isolate the patient ; burn the excreta ; disinfect bed and body clothing, by exposure to a steam heat of at least 230" ; disinfect the house. TYPHOID PEVER CONNECTED WITH MILK-SUPPLY\ By H. B. AllExV, M.D. Professor of Anatomy and Pathology in the University of Melbourne. On or about the 16th of March, 1879, the son of a milkman, named M., residing near the west end of Jolimont Place, fell ill ; in a few days, distinct symptoms of typhoid fever presented themselves, and the disease ended fatally on the 2nd of April. Of ninety-three households in ^Melbourne and its suburbs supplied by the milkman in question, twenty -three were visited by the fever ; forty-three individuals were attacked, of whom three died. From this short summary, I may proceed to discuss— («) the sanitary condition of Jolimont ; (b) the history of the illness of young M. ; (c) the milk-supply ; (eriod, the fever did not attack a single individual in Jolimont who did not drink the miUc in >/uestion. One family as a rule obtained milk from another source, l)ut took milk from Mrs. IM. once, about March 21, when young M.'s illness was declaring itself The servant drank half a cupful of this milk ; a week later she was laid up with typhoid fever. Street Plan of Jolimont. RICHMOND ROAD N N EW TI P <^ JOLIMONT PLACE «<<• M s-v JOLIMONT STREET 1 2 w R S W o Hd H m m W iz; C5 < If we compare the different streets in Jolimont with one anothei-, very striking peculiarities present themselves in the prevalence of M 2 164 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. typhoid among the customers of Mrs. M., as is shown by the following table : — Statistics of Households and Individuals Supplied with M.'s Milk. STREET. Aspect of Jolimont. NUMBER SUPPLIED. NUMBER VISITKD BY TVPHOID FEVER. Households. Individuals. Households. Individuals. Jolimont Place Jolimont Terrace . . Jolimont Square Agnes Street Jolimont Eoad Jolimont Street North . . East North . . Centre . . West South . . 5 6 3 9(6) 5 3 26 i 2 33 2 (a) 32 2 44 (b) 1 5 (h) 30 i 14 1 2 5 9(6) Total .. 31 179 11 ! 20 (a) One of these two houses, in which four cases occuiTed, is at the corner of Jolimont Terrace and Jolimont Place. (6) This includes the family in which M.'s milk was taken only once, a week before the servant showed signs of typhoid fever. Thus it is seen, that the high and comparatively well-drained parts of Jolimont were visited by the disease, while the two low-lying streets on the south and west, which receive the drainage from the higher ground, escaped entirely. It is difficult, to explain this immunity; in only one house in these two streets was M.'s milk scalded, and there only on very hot days. But it may be remarked that these two streets are farthest from the new tip, which seems to have been the great sanitary blot of the district. Thus ten cases occurred in Jolimont Place and Square, and the adjoining corner of the Terrace, which all abut directly on the new tip. Of the remaining ten, nine were in Agnes Street, which is more or less built in on both sides, comparatively shut in, and which leads southward from the centre of the tip. The other case was a weakly lad in Jolimont Terrace, who drank a pint of the raw milk daily. The next point to consider in the development of this outbreak is, the number of cases of fever that occurred weekly in Jolimont, after young M. fell ill on March 16. Disinfectants were tirst ordered to be used on the 21 St. Weekly Number of Cases of Typhoid in Jolimont, after March 16, 1879. From March Hi to March 23. From Marcli 23 to Jlarch 30. Prom March 30 to Aprrl 6. From April 6 to April 13. From April 13 to April 20. From April 20 to April 27. From April 27 to May 4. From Mav 4 to May 11. — 4 7 5(a) 3 — — 1(&) (a) And two cases of febricula. (6) This occurred on May 5, in a house adjoining another iu which an earlier case commenceil on April 7. , More than seventeen persons, who had been drinking this milk, scattered during the time of the outbreak — some to England, some to 165 * INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Map of East Melbourne. CO o Swampy 1 iSn qipps f — V 1 " ^'"v. " eared suddenly among the customers a week after the primary case commenced its course in the house of the milkman M. The outbreak ((uickly reached its greatest degree of prevalence, and as quickly subsided. (2) Wliat was the nature, and v:hat the method of this contamination / Two explanations were offered ; one, that the milk was poisoned through the cows drinking foul water, and feeding on the decaying A-egetable rubbish found in the tip. Two objections to this arise at once : — firstly, cows belonging to other dairymen depastured in the same paddocks, and drank similar water, while the milk yielded by them did not induce fever; and secondly, the milk obtained by M. from Croxton Park induced fevei', just as did Jolimont milk, though not in so large a })roportion of the individuals supplied. The milk being thus derived from two distinct sources, and yet carry- ing the same virus with it, whencesoever it was obtained, we are driven for an explanation to the milkman himself and his cans. As before remarked, " all the cans were subjected to the same treatment, being manipulated Ijy a i)erson who was taking a large share in nursing a patient suffering from typhoid fever." These cans stood all night within ten to fifteen yards of a barrow containing a mixture of earth, stable manure, and typhoid stools, to which was added from time to time (so I was told) some disinfectant solution ; similar solution was used also in the bed pan itself, but none of these precautionary measures were adopted during the first five or six days of the patient's illness. It is noteworthy that, while the fever ])oison was being distributed, the milk that conveyed it kept sweet for days. The cleansing of cans with soda, hot water, itc, may prevent milk from swiftly turning som-, but will not destroy the typhoid virus ; nay more, this virus may possibly be introduced into the cans in the very operation of cleansing, scrubbing, and wiping them. 1G8 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. As far as I could judge, it mattered little who served tlie milk to the customers, or what had been the closeness of his or her connection witli the sick room. But the evidence in this respect is very incomplete. The condition of M.'s house and yard is the subject of many conflict- ing statements ; probably care in many things was accompanied at times 1)y neglect of others. Thus, though M. could assure me that the cans which he used never entered the house, yet he was unable to speak with certainty about the cans and milk used in the Jolimont supply. He was aware that in some instances his orders, " never to supply cold milk to anyone," had been disregarded. The Jolimont customers, in fact, ran many risks peculiar to them- selves ; the cans used in supplying them were more constantly near, perhaps in, the house ; the cows were frequently milked by persons engaged in nursing a typhoid fever patient ; the distrilnition of the milk Avas less methodical, and altogether the work was done in a slipshod way. (3) Was the milk thus contaminated aJAe to p>^'oduce typhoid fever in those inlio dranh it, in the absence of certain other conditions ; if not, tvhat were these conditions ? The limitation of the outbreak among M.'s customei's to certain definite districts shows clearly that the first part of this question must be answered in the negative. The same milk being supplied in the same daily rounds, ty})hoid fever prevrdled extensively iu some quarters, and was entirely absent in others. No individual or family ])redisposition can explain this away. Defects of drainage or of ventilation in single houses will not touch the point at issue ; it is idle to suppose that there were grave sanitary defects in all the houses of M.'s customers into which typhoid entered, in East Melbourne and in the eastern half of Melbourne proper, while all the fever-free houses in West Melbourne, Fitzroy, Collingwood, kc, were in such matters with- out reproach. No, we must look for conditions affecting districts, and not merely single dwellinr/s. The problem presented is one of the utmost difficulty, yd the facts seem to show that, apart from some localising conditions, the poisoned milk would not, unless in exceptional cases, piroduce an outln-eak of fever ; and even when these conditions were present, personal and family peculiarities, age, drainage and ventilation of special houses, &c., would be most important factors. I can only guess the nature of the localising conditions. Nearness to offensive tips for rubbish api^eared to be the most potent factor in Jolimont. In East Melbourne, proximity to low-lying, badly drained ground seemed the chief condition common to almost all the houses in- vaded. Of the different incidence of the fever in the eastern and western halves of Melbourne city, I can offer no explanation. In regard to the milk obtained from Croxton Park, it is extremely strange that the families fii'st sujjplied in Clifton Hill and Collingwood should go free, that the families next visited in East Melboui'ue and the eastern half of Melbourne should suffer in so many instances, and that the customers in the western part of Melbourne should enjoy immunity. 1 do not feel justified in taking up your time with vague speculations, but simply place the facts before you, hoping that, in any future outbreaks, in- vestigators will not be content when they have convicted milk of being the carrier of contagium, but will closely study the conditions which govern the prevalence of the fever among the families and individuals supi)lied with the contaminated milk. TYPHOID FEVKR — HISTORY OF AX EPIDEMIC. 169 TYPHOID FEVER— HISTORY OF AN EPIDEMIC. By A. V. Henderson, M.B. et Ch.B. An epidemic of typhoid occurred in the year 1887 in the township of Lilydale, a township composed in the greater part of hills and dales, but which, in one particular ])art, rather thickly studded with houses, is a large flat, undrained, and in a generally insanitary condition. Through the township runs an ever flowing creek, which contained a clear and wholesome sup[>ly of pure drinking water up to the time of its becoming tainted. This district had been free from ei)idemics of this fever, although isolated cases had occurred. It was from the investigation of the sporadic cases that I gleaned, to my mind, the most valuable information. The following are the condensed facts of the outbreak. In January of the year 1887, there was what would be considered a drought in this district, which as a rule is well supplied with rain water, in the winter months there being rather too much rainfall. At this time the domestic supply had run very short, being in most cases sujiplied from underground brick tanks. The water in these tanks had become very low. and in many cases they contained only a foot or two of stagnant water. The drains, which are of tlie primitive type, were full of decaying and decomposing matter. In fact, the residents had everything ])repared to welcome a visit from such a disease as typhoid. I speak principally of those who resided on the tlat, undrained part before mentioned. It was when this state of affairs existed that a groom, named D., came to Lilydale to recruit, as he had not been feeling well for some days. He stayed at a grocer's sho)) and boarding-house kept by a man named P.; not getting any better from the change, he came to consult me, when, after seeing him two or three times, I pronounced him to be suffering from typhoid fever, and ordered his removal to the hosjiital in jNIelbourne, where he Avas treated for enteric fever. His wife had come up in the meantime to nurse him, and began to show premonitory .symptoms ; as soon as she consulted me, I advised her removal. She went to the hospital also. Closely following on the departure of these two cases, the wife of the storekeeper took ill, but did not send for me until some time after she had felt ill, and had served groceries in the shop. All precautions possible had been taken to kee[) down contagion, but the harm seemed to have been done. One of the children (belonging to the boarding- house keeper) then contracted the fever, and in quick succession arose other cases in this house and outside. The next door neighbours — who lived right upon the creek — were the subsequent victims. Their child, who had been accustomed to play with the boarding-house keeper's children, being affected first ; this being the probable source of contagion between these two families. It was from this house ujjon the creek that a great deal of the subsequent mischief arose. I found out, when called into this house, that it was the custom of the occui)ants to throw most of their refuse into the creek, and as the bedroom doors aljutted on to its banks, most of the excreta would find its way into the water. It was some time after 170 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. this cliild had been ill that I was called in, so that the mischief had been done. All along the same side of the street as the store arose a number of cases, almost every house holding a victim. As the creek water was now affected, and as numbers of the peojole had been to the creek for a supply, how far these subsequent cases were due to neighbourly intercourse, or to the creek water, it would be hard to say. All along the banks of the creek below stream (not above it) the residents contracted the fever, and all of these drank from its waters. The navvies working on the new line of railway from Lilydale to Healesville, whose tents were pitched on its banks, also suffered severely. In a different situation to all these cases in the township, and where the creek water was not used, I was surjirised to find typhoid had begun with another series of cases, but soon learnt that they arose from a case which had left the house on the creek. A mother, Mrs. W., a widow, had taken her little girl away from here, on learning that typhoid fever was in the house, and had taken her to this part of the township, but too late, as she soon showed symptoms, and was treated by the mother for some time, until fever symjitoms set in, which prompted her to apply to me. The next door neighbour who used to run in, and help to nurse the little girl, not knowing what the disease was, and what precaution to take, as can readily be understood, contracted the fever, and from them again their relatives and friends. Thus the disease took full possession of the townshi}), whose general system of drainage and sanitary condition favoured its spread. And so the succession of cases all originated from the one imported case, the virus acting quickly in constitutions rendered liable to its action by the predisposing causes then existing. This epidemic shows how a ruiming creek can be contaminated by the excreta from a typhoid patient, and carry the germs far and wide to numbers of unsuspecting people. Many more than the number which came under my })ersonal care must have suffered from drinking its water, and gone away to their homes, or to the hospital. Thus, if a running creek, in a country district, can be polluted to such an extent by one case, how much more easily can a reservoir be con- taminated, and how many more lives can this reservoir then endanger. With what extreme care then should the domestic supply of a large community be guarded, or what dire results may follow. The illustra- tions I have just given point to the moral, and the same would a])ply to sanitary conditions. For suppose a dwelling-house to be situated near a reservoir, at a higher level than its banks, and suppose an unsuspected case of typhoid came to this dwelling, what is to prevent the contamination of that reservoir? Hence the injudiciousness of having near any domestic water supply, dwellings of any kind. Now, as to sporadic or isolated cases of typhoid fever. I had collected and investigated a great many cases, out of which I preserved a few typical ones. I mention here only three or four cases. From these, I have been led to this belief : " That in most sporadic or isolated cases, the original cause of the fever lies in the virus generated in stagnant decomjiosing water." The first case is this : — A young man, about 23 years of age, named H., who resided about seven miles away from Lilydale, and whom I visited professionally, was TVPIIOID FEYRR — HISTORY OF AN EPIDEMIC. 171 sutfeiing from a tyiiical case of typlioitl fever. On making the usual inquiries anil investigations, I found the house situated on vising ground in a jiretty locality, the drainage was very good, jirivy clean, and all sanitary conditions of the best. The young man was building a house at the time he fell ill, intending to get married and live in it with his wife as soon as finished. He Avorked by himself, had not been awa}^ from home for .six weeks, had had all his goods in from a place called Wandin for some time previous to this ; and his mother, whom he lived with, had not been away from home, neither had they seen anyone. On asking questions about the water used for domestic purposes, 1 found they had run out, and were getting their sujjply from a tank close by, which was not used, and which was very low as to the depth of water it contained. On examining this fluid, I found it was dirty, had a nasty decompos- ing smell, and was full of aniinalcula^. The patient said he often felt sick for some time after drinking it, but he was obliged to use it, as it was hot weather, and he being busy had no time to go farther for better. In this case I could find no other cause, after fully investigating all conditions, and therefore came to the conclusion that this case of typhoid originated from the stagnant degenerated water which the patient had indulged in. And given one case, where is the contagion to stop in such a communicable disease, providing the surrounding circumstances are favourable 1 In this case, everything was isolated. It was a country farm residence, with no houses near, lieing built upon a farm of a con- siderable number of acres. In the other case, a young man, named J., aged 19, who lived about 9 miles from Lilydale (in the country), came in to consult nie, and having ascertained clearly that his sickness was typhoid, I recommended his removal to the hospital, where he was treated for such. I made all inquiries, and found that he had not been to Lilydale, and that when he left home it was to go in the opposite direction ; and as that had been only once for a considerable time, he could vouch for the fact that he had not met anyone, except to exchange a passing salutation. The water this patient drank was in a somewhat similar condition to the previous case, and the other sanitary conditions were very good. I could come to no other conclusion than that which I arrived at in the first case cited. The next cases occurred in a family living 12 miles away from Lily- dale. All enquiries led to the same results. Three of the family contracted typhoid. They had not left their homes for some weeks previously, and everything pointed to the domestic water as the primary cause. In the year 1885 a young fellow, W. B., aged 21, working at Mitchell's lime kiln, took ill at his home and sent for me ; he developed a typical case of typhoid. The house he was living in with his mother, father, and brother, was fairly well drained. The water used for domestic purposes seemed good, and as he had not mixed in any way with people from Melbourne, or had been there on a visit, I could not account for his contracting the fever, until I learnt he remead)ered that some days previously, having felt thirsty after working hard on a hot day, he had taken a drink from a stagnant pool of water in one of the paddocks, which he pas.sed through on his way home. 172 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. I saw this case early, and kept him well isolated, and used all pre- cautions with the excreta, in which I was helped by his parents. His brother, who was in the same house and used to nurse him, took the fevei', and was sent to the hospital, but these were the only two cases which occurred that year in Lilydale. I took all possible care in collecting information and investigating these cases, in all of which I was forced to come to the same conclusion. What the constitution of the germ or poison is, I do not pretend to state, but only that in the stagnation and decomposition of water a virus is generated, which is capable of causing typhoid fever in the human system. It is noticeable that most cases arise after a drought, and the greater the duration of that, the greater the number of sporadic cases. Dr. Murchison held the opinion that typhoid fever was the result of putrefaction, having called it pythogenetic, or fever born of putrescence. If he would consider water in a state of stagnation, and consequent decomposition, as putrescent, then the result of my investigations would corresjiond with his. It was for these reasons that in my re"[)ort to the Central Board of Health I recommended the boiling and filtration of water, heat being the best destroyer of the virus. These precautions I had practised in Lilydale (by the residents), the year following the epidemic, and I found that though a good number of cases arose, not one occurred in which these precautions had been taken with the water supply, and in those cases which arose, there was total neglect of such ; in fact, disregard towax'ds the domestic su])ply of water in country places is great, and it is not uncommon to find that underground tanks have not been cleaned out for years. In country districts investigations are more easily carried out, and sporadic cases are far apart, giving greater facilities to glean informa- tion, and all the attendant difficulties which arise in thickly populated towns are lessened. A NOTE ON THE INCUBATION PERIOD OF ENTERIC EEVER. By Jos. C. Verco, M.D. Lond. Joint Lecturer ou Medicine at the University of Adelaide. Hon. Physician at the Adelaide Hospital, &c. The patient, a young man, was first seen by me in private practice at his home on May 1st, 1888. He had come from Broken Hill, N.S.W., the same day, where he had been ailing for about a week. He was feverish. On May 4th he developed typhoid roseola, had an unusually abundant eruption of spots in a few days, and passed without unfavouraljle symptoms through a typical attack of enteric fever. On the morning of May 17, one of the servant girls, who had been complaining of headache and general malaise for a day or two, was seen. Her temperature was normal, but she was sent to bed. At night, the thermometer registered 100*4°, the next morning 101', in the evening I NOTES ON TYPHOID FEVER. 173 101°, the following morning 100'4°, and in the afternoon above 102°. On the 19th, she was sent to the Adelaide Hospital, where she developed undoubted ty])hoid, with abundant spots, and with a continued fever, lasting until June 7th, the first occasion on which the night temperature was normal. On May 21st, I saw the other servant girl, and learned that she began to have headache on the 18th of May, followed by stiffness of the neck. She was feverish, and was sent to the Adelaide Hospital on May 22nd, where slie had an attack of enteric, the pyrexia disappearing at night for the tirst time on June loth. There had been no case of typhoid in this house since Dec. 1886, sixteen months before. At that time, one of tlie sons came down from Teetulpa Goldfields, where he had contracted the fever. Within three weeks of the arrival of the patient from Broken Hill, both the servants were aftc'cted. There can be very little doubt, therefore, that they con- ti'acted the complaint from the recent arrival, and not from any germs derived from the more remote case. The usual precautions were taken, in reference to disinfection with carbolic acid of all clothing and evacuations, but it appears that while the nurses were at their breakfast, the serving girls relieved them at the bedside, and watched the patient, and one of them had washed the patient's linen after soaking in carbolic acid solution. But however contracted, it certainly was communicated ; and so its contagious nature is established, contraiy to the opinion of some. The period of its incubation is, to some extent, fixed for us. Within fifteen days from the entry of the patient into the house, the first girl began to grow ill, and within seventeen days the second one. If, there- fore, infection took place on the first day of his arrival, the incubation period woiild only be a fortnight or sixteen days. It coitid not possibly have been longer in these two cases. And inasmuch as it is not probable they were infected quite so soon as the first day, the incubation period for both of them was most likely under tiuo weeks. NOTES ON TYPHOID FEVER. By J. W. Springthorpe, M.A., M.D. Melb., M.R.C.P., Lond. Physician to the Melbourne Hospital, Lecturer to the University of Melbourne ou Therapeutics, Dietetics, and Hygiene. The following is the statistical account of the cases of typhoid fever under my care in the hospital during the past season ; — No. of Cases. Males. 1 Females. 1 Ages. Duration of Fever. Relapses. Deaths. Between 10 & 20-24 ) 84 62 22 „ 20 & 30-53 1 Average 26 clays 1 ., 80 & 40-7 ) 11 13 48 of the cases were admitted in January, February, and ]March, and 18 within the next three months. In 27 cases, constipation was marked ; 174 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. in 37, diavrlicea was severe ; in 16, the temperature rose above 105° 1 had four rehipses ; spots were found in about half the cases ; in 10, haemorrhage occurred ; 6 had pneumonic attacks ; in 3, there was peri-typhlitis ; in 3, thrombosis of the left leg ; in 6, perforation ; in 4, pregnancy, the 2 in the early months aborting ; in 1, there was left hemiplegia ; in 1, parotiditis ; and in 1, multiple pulmonary haemorrhage. One had had a previous attack. The causes of death were — perforation in 6, luemorrhage and exhaustion in 2, pulmonary complication in 3, hyper-pyrexia and cardiac failure, each 1. Four cases were moribund on admission. There is nothing new to add regarding treatment, except that antipyrin, in single doses of 15 grains, was found very useful when the temperature remained high after cold sponging and ordinary diajihoretics, and that nepenthe (m. xv.) taken at night saved several lives, when there was delirium and diarrhoea, the sncc. eucalypt. rostr. 3j being a useful addition. Regarding the incubation period. On several occasions, a crop of fresh cases was noted in from two to three weeks after a rainfall. As to diagnosis. — Difficulties were found in cases of tuberculosis, tubercular meningitis, gastro-enteritis, and the gastro-intestinal form of influenza. Cases of the three first were differentiated upon well recognised general grounds. No doubt many cases are called typhoid, esj^ecially amongst children, which are better classed under gastro- enteritis. An investigation into the influenza ejndemic has led me to the con- clusion that there is a form of continued fever existent amongst us, influenzal in origin, yet simulating typhoid fever in many particulars. I have seen some dozen cases in which typhoid fever was so simulated, and some three in which an exact diagnosis is open to dispute. At pi-esent cases are coming into the hospital of an anomalous character, they are iiot the ordinary typhoid ; my cases of such I can class as gastro- intestinal forms of influenza. Some cases may be explained as true typhoid supervening after an influenzal attack. Some have developed an influenza sore throat after the typhoid has begun, but the majoiity are quite distinct. The points in the differential diagnosis are as follows : — In the influenzal class the incubation period is found to be short, the onset sudden, the patient generally hepatic. There has been influenza in the same house ; there is a history of an influenza attack in the patient, and examination of the throat will show the naso-pharyngeal catarrh, the sticky adherent mucus, the rounded hillocks, or the ulcers or sloughs characteristic of the disease. There is pyrexia, like that of typhoid in height and continuance, but generally coming down within ten days. Profuse sweating from the outset, and marked prostration are seldom if ever absent. Instead of the suffused heavy face, the apathy, the delirium, the dry brown tongue, we have face and expression natural, intellect unimpaired, tongue coated, and no epistaxis. There are no spots or tympanitis. Constipation is present at first, possibly with local pains, in some cases suggesting sub-acute rheumatism ; and when diarrha'a occurs, the stools are those of milk diet, not " pea soup," the light colour alternating with darker, the watery character being at times rei)laced by the natural consistence. Some cases continue in- definitely a puzzle to their attendants, and end in sloughing of the mucous coat of portion of the alimentary canal, with or without the VARIATIOXS IN THE PATHOLOGICAL PROCESS 1\ TVPIIOII) FEVER. 175 supoi-vention of pulmonary oi- intestinal tuljeicular miscliief. In the mikler cases, however, the after history is further evidence of their non- typhoid character. The jiatient can he got up and placed on ordinary diet at a time when the attemjit would have almost inevitably produced a relapse in an ordinary typhoid case. Finally, cases of this sort were noticed and satisfactorily accounted for at a time when the onus of proof was, not to prove the case non-typhoid in character, but the reverse. During December, however, many fresh cases have arisen, wlierein the onus has been to prove them non-typhoid ; and by applying the differential diagnosis already arrived at, a separation of cases has been possible, and one wliich, in my judgment, is based upon a real ditference in etiology and pathology. The nature of the lesion, and its viodus openoidi in typhoid fever, are known to all ; the lesion and substratum of intluenza are discussed in another jiaper. XOTES ON VARIATIONS IN THE PATHOLOGICAL PROCESS IN TYPHOID FEVER. By H. B. Allex, M.D. Professor of Auatomy and Pathology in the University of Melbourne. The incubation of typhoid fever is sometimes accompanied by intense depression, the pulse being abnormally slow and very compressible. This depression may pass off, to some extent, with the development of the fever, but it sometimes persists, and must largely govern the treatment. Even when strongly marked, it is not necessarily followed by a severe attack. The usual insidious commencement of typhoid is sometimes replaced by a sudden onset, with vomiting and purging, and other symptoms of gastro-intestinal irritation, so that the case may resemble one of irritant poisoning. The precise cause of these phenomena is not, so far as I am aware, clearly ascertained. In some cases, the fever runs a short typical course. Probably the swollen follicles of the agminated glands slough separately, the patches ac(juiring a finely-pitted appeai'ance (^plaqties a surface reticulee), and rapidly healing. In other cases, after death, patches are found in all stages, some ulcers being thoroughly cleaned, with bases formed by the circular muscular fibres ; others, higher up the bowel, being coated with sloughs in jn-ocess of separation ; while others are still swollen and purple. These are not cases of relapse, properly so-called, but of successive poisoning of separate patches. They are found in most patients who die after prolonged fever. I believe that a dose of calomel, given during the first week, before the sloughs are fully formed, does much to prevent this successive invasion of patches. In the pathological theatre, the varying extent of ulceration is very striking. There may be but a single ulcer ; yet this may be deep, may be accompanied with liigli fever, and may finally undergo perforation. On the other hand, the agminated glands may be very generally 176 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. affected ; and when a large surface is thus implicated, although the patches are simply tumid and angry red, the shock to the system may, in some degree, resemble that of an extensive burn. The solitary glands are sometimes little affected when Peyer's patches are deeply ulcerated. The intensity of the intestinal lesion is even more variable. In fatal cases, there may be nothing more than intumescence and pitting of a number of patches. But, at the other extreme, there may be rapid and great swelling of the solitary and agminated glands, followed by deep .sloughing. The inflammatory accumulation of cells iii the lymphoid tissues may not be limited to the follicles, but may be general through- out the mucous membrane of the affected area. Such general tumefaction is, I believe, an occurrence of very grave import. When the intestinal lesions develope in this rapid intense fashion, the mesenteric glands also become so choked by aggregation of leucocytes, that caseous infarction may ensue. This acute infarction differs gi eatly from the slower, more bloodless caseation seen in tubercular processes. In other rarer cases, the mesenteric glands undergo suppuration or sloughing. The perforations which occur in the agminated glands are of two kinds — fii'stly, there is the pin-hole ])erforation, a minute rounded aperture at the bottom of a shelving ulcer ; and secondly, larger, more irregular perforations following sloughing of the floor of the ulcers. The pin-hole perforation results from the depth of the original sloughing ; it seldom occurs in more than one patch. The large perforations are not due to the separation of the primary sloughs, and to molecular changes consequent thereupon, but to later processes of secondary sloughing, probably induced by the ingestion of biscuits, apples, or other improper articles of diet. The pin-hole perforation, therefore, forms much more slowly ; it is not preceded by marked symptoms of iriitation ; the intestinal contents cannot esca])e so freely into the peritoneal cavity, and what little does escape is sometimes encapsuled by inflammatory adhesions. Perforation due to secondary sloughing is not infrequently multiple. These points have a bearing on the possibility of surgical interference. The degree, in which the large intestine is implicated, varies greatly. In some cases, the large bowel escapes altogether ; in others, the lesions are confined to the caicum ; in others, they extend throughout part or all of the colon, even into the rectum. In certain cases, I have found death caused by hremorrhage from ulcers in the ciecum or colon. The vermiform appendix is often affected, as might be expected, seeing that its inner surface is lined throughout with lymphoid follicles ; the lesions are usually limited to swelling and pitting, but I have known perforation to occur. Clinically, relapses vary greatly ; sometimes there is a re-accession of fever for a few days, with evening exacerbations ; sometimes a complete, though short, re])etition of the attack. Between these extremes, various intermediate forms occur. So also, pathologically, in relapses which prove fatal, the morbid apjoeai-ances display great diversity. In many cases, the ulcers in Peyer's patches, near the ileo-ctecal valve, will be found in various stages of cicatrisation, with pigmentary deposit in the edges, while patches further removed will be intumescent, or finely pitted, or sloughing. Sometimes patches will be found, only part of which suffered in the first attack, the resulting ulcer being clean based, with VARIATIONS IN THE PATHOLOGICAL PKOCESS IN TYPHOID FEVER. 177 shelving,' edges, and having ])erliiips transgressed the lateral limits of the agniinated gland ; while in the relai)se, the remainder of the gland suffers, being found swollen, with the slough still adherent. 8uch cases offer the most striking illustrations of the well-known fact, that the lymphoid follicles, in different parts of the small intestine, suffer very unequally. Sometimes the large intestine escapes in the first attack, hut in the relapse, when the ileum is jierhaps little affected, the whole length of the colon is studded with tumid or sloughing solitary glands. It is well known that typical relapses seldom prove fatal. The fatal relapses, to which I have referred, were mostly cases of re-accession of the disease during the healing of the ulcers of the fii-st attack. Not seldom, the history of the first attack was very obscure. A phenomenon, which has not excited much attention, is late sloughing, occurring long after all ordinary sloughs have separated, and at a time perhaps when the ulcers are in varied stages of cicatrisation. These late sloughs may be far removed fiom the original ulcers. Thus I have seen large patches of sloughing, affecting all the coats of the jejunum, within a few inches of the duodenum ; 1 have seen sloughs in the splenic and in the sigmoid flexures of the colon. Some of these ajtpear to be neurasthenic ; others commence in ha^morrhagic erosion. I incline, therefoi'e, to connect some of these late sloughs in point of causation with other still later ])henomena, which may occur during imperfect convalescence, such as necrosis of ribs, progressive dilatation of the heart, &c. These occasional evils, which snatch patients away when the grave dangers appear past, serve as a warning, that typhoid patients need watchful care for a con- siderable time after apparent complete recovery. When neurasthenia persists, the patient should be watched closely, for extensive lesions may develop very insidiously. IlajmorrhagH from the intestine, daring typhoid fever, mav be due to oozing from distended capillaries over a considerable surface, or to oozing from the angry edges and bases of ulcers, or to the opening of a considerable A'essel by sloughing. In some cases there is a distinct tendency to haemorrhage, evidenced not only by copious early epistaxis, but by jjulmonai-y congestions, running on into hsemorrhage. In some such cases, intestinal hsemorrhage is followed by distinct improvement. The haemorrhages resulting from high vascular tension must be distinguished from those due to depraved condition of blood, as in ])urpura. Tubercular infection of typhoid ulcers has not received much notice ; yet in certain years I have found several cases. Mistakes in diagnosis of such lesions can easily be made. Typhoid iilcers are frequently, in cases which have lasted five or six weeks, wider transversely than longitudinally; but this does not imply tubercular infection. Minute patches and tags of fibrin may be found on the serous surface, opi)osite deep idcers, and may be mistaken for tubercles. Acute caseation of mesenteric glands in the early stage of fever should be distinguished from tubercular changes. Well-marked secondary local tuberculosis usually occurs late in the course of the fever. Many ulcers will present the characters typical of typhoid ; but some, near the valve, will have somewhat thickened bases, and in the sub-peritoneal tissue opposite there will be distinct grey grains, and perhaps lines of similar grains running to the mesentei-ic edge. The nearest mesenteric glands may N 178 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. present patches of caseation, and, at the edges of the cheesy areas, tubercles may be indistinctly visible. But, much more rarely, distinct tubercles will be seen on the peritoneal surface, opposite ulcers from which thick sloughs are only commencing to separate. I have never seen any generalisation of such tuberculosis in the peritoneum. In some cases of secondary tubei-cular infection during typhoid, I have found old encapsuled cheesy matter elsewhere in the body ; but in other cases, no traces of old tubercular processes were ]iresent, and the patients had been pi-eviously robust. Doubtless, the bacilli of tubercle are widely disseminated in the atmosphere. We must frequently inhale and swallow them. The issue depends largely on the presence or absence of a prepared culture bed. I am of opinion, rightly or wrongly, that too much has been made of typhoid fever as inducing subsequent phthisis. I fancy that in many cases in which phthisis has been said to follow typhoid, the mischief has been purely tubercular from the outset. Cases of pulmonary tuber- culosis, which begin acutely, not infrequently mimic typhoid. The occurrence of sweats, without corres|)onding fall of temperature, is sometimes a notable diagnostic symptom. But the appearance of the patient ma}' be sufficiently characteristic. Endocarditis is a possible complication of tyjthoid, which may easily be overlooked, with evil results to the patient. Cardiac thrombosis now and then occurs, with embolism in the spleen or elsewhere. Thrombosis of the iliac veins, wuth phlegmasia, is more frequent. I may pass by the familiar pneumonia, and barely mention the occasional occurrence of pyaemia, tetanus, tfec. No matter how severe the head symptoms attending typhoid may be, even though wild delirium occur, instead of low muttering, meningitis is not found. It is an extremely rare complication of typhoid fever. Yet, in certain seasons, head symptoms have been so ]>rominent, that jihysicians have called the disease " nervous fever," as distinguished from typhoid. I have often thought that man}^ cases of typhoid are complicated witli septicasmic ])oisoning, by absorption of soluble poisonous substances from the foul contents of the intestine. Still more is it borne in u]ion me, that a degree of urajmia is often present ; there is rapid destruction of muscular tissue, while the kidneys are more or less unfitted to discharge their full functions, by reason of the febrile state. This may explain why so many strong muscular subjects die; while slighter, more delicate, patients recover. It is with some hesitation that I have ])laced these scattered notes before you. There is little that is new in them, as may be seen by comparing them with the masterly descriptions given by the late Hilton Fagge in his " Principles and Practice of Medicine." But I have not mentioned, even incidentally, a variety or a complication of the morbid process which I have not seen, and this must be my excuse for occupying your attention. THE COLD BATH TREATMENT OF TYPHOID FEVER. 179 THE COLD BATH TREATMENT OF TYPHOID FEVER. By F. E. Hare, M.B. Ecsident Medical Officer, Brisbane Hosjjital. Although the treatment of tyjihoid by cold bathing has been fre- quently and powerfully advocated on the Continent, it does not seem to have gained many supporters in England or the colonies. The reason for this is not far to seek. The bath has been regarded as a heroic remedy, justifiable only in desperate cases; whereas the very essence of the treatment lies in the fact that it is above all a prophylactic against the effects of continued pyrexia, and not a curative proceeding in the ordinary sense of the term. Regarded from this standpoint, it may be said to be absolutely free from risk of any kind. Holding such views, I began the treatment at the Bvisl>ane Hospital. Through the indulgence of the visiting staff, to whose kindness I am much indebted, I was enabled to put every patient, who was admitted on or after a certain date, upon a systematic course of cold bathing, very similar to that recommended by Brand. I will first briefly describe the treatment in a case of ordinary severity. Should the patient not have reached the eighth day of fever, the bowels are freely moved by castor oil, or some other unirritating purga- tive. He is then put upon the ordinary diet of beef tea and milk, administered in regular quantities at regular intervals, with an unlimited sujjply of iced water to drink. Brand's rule is observed in bathing, i.e., the temperature is taken in the rectum every three hours, day and night, and whenever it reaches 102"2° F., a bath of about the temperature of 70° F. is given. The first does not exceed ten minutes in duration for an adult. The temperature is not taken while the patient is in the bath, but half-an-hour after its termination, and always in the rectum. The fall should be to 101°, or lower. Should this not be approximately attained, the next bath two and half hours later is prolonged by about five minutes, and so on. It is rarely necessary to continue the immersion for more than half-an- hour. If this be insuflBcient, the tem])erature of the bath water is lowered to G5°, or even 60° F. In most instances, the temperature only just reaches its former level by the time the next bath is due, but in a few, it rises with great ra])idity, attaining its maximum in an hour and a half, or sooner. Here the frequency of the baths is increased, so that as many as twelve in the twenty-four hours may be given. Stimulants if required are given before the bath, and nourishment half an hour after its termination, when the fail of temperature is being noted. The interval is wholly devoted to sleep. In ordinary imcomplicated cases, this treatment is carried out strictly from the day of admission, until such time as the temperature ceases to rise to 102 "2° F. The approach of convalescence is seen in the gradually diminishing number of baths, so that usually for seme days before they cease, one in the afternoon or evening is all that has been required. Nervous dread of the bath is the most common difficulty met with. Generally, this ceases after a few immersions, but sometimes it persists, or even increases. Such cases are always benefited by a stimulant, just N 2 180 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. before the bath ; but the addition to this of a small quantity of morphia is almost invariably successful. I have seen a patient who had a horror of the bath thoroughly enjoy it after an eighth of a grain of morphia. Cases marked by persistent high temperature early in the attack, before signs of failure have appeared, rarely show any nervousness about bathing, a most fortunate fact, for such cases are precisely those who derive most benefit from it. The only absolute contra-indications are jDerforation, haemorrhage, and advanced cardiac debility. The two former, of course, require perfect rest ; the latter precludes anything in the nature of shock. Although the temperature is taken as the best indication for regulating the number and duration of the baths, yet almost all the other symptoms are as favourably modified. Circulatory System. Coincident with the fall of temperature, the pulse iliminishes in frequency, often by twenty or more beats a minute, and at the same time it becomes smaller, hai'der and more sustained, indicating a general I'ise in blood pressure. Sometimes, indeed, this vaso-constriction is excessive — the pnlse, though reduced in frequency, becoming thready, the face and extremities blue. These symptoms need cause no alarm. They are, if anything, of favoui'able import, and can alwaj's be relieved by small doses of alcohol, which here is probably effective in virtue of its action as a vaso-dilator. In most cases of any duration, a certain amount of cardiac debility gradually appears, as shown by the increasing frequency of the pulse in proportion to the temperature. In those, however, that have been sys- tematically bathed from an early date, it is unusual for this symptom to I'each any degree of severity. But occasionally, in spite of the ti'eatment, it continues to increase, and it then becomes no easy matter to discriminate at what point the benefits of the bath are more than balanced by its danger. In cases of doubt, the following plan is often of great advantage : — A single dose of from 30 to 40 grs. of quinine is given about ten p.m. This will usually cause a fall of temperature, lasting from twelve to thirty-six hours, during which time of course the patient will have a complete rest from the baths. Its effect on the pulse is to reduce its rate, and increase its force. That this tonic or stimulant action on the circulation is to a great extent independent of its action as an antipyretic, is usually very evident. For, in a few cases, although the drug fails to reduce the temperature appreciably, the pulse is almost invariably slowed and strengthened ; and in the majority, where the pulse and temperature fall together, the former continues slower long after the latter has risen to its former height. Other antijiyretic drugs, such as antipyrin, antifebrin, the salicylates, &c., have not, according to my experience, this power of increasing the force of the circulation, but have seemed to act unfavourably in the opposite direction. The rapidity of their action (which is no gain where the bath system is used), is quite counterbalanced by the evanescence of their effects. I should Jicre say that, except in the cases already mentioned, the condition of the circulation, as evidenced by the heart sounds, and more THE COLD BATH TKEATMEXT OP TYPHOID FEVER. 181 especially by the frequency of the pulse, is regarded as the only indication for stimulants. Murchison's rule is for the most part adhered to, although the limit of twelve ozs. of brandy per diem — beyond which he considered it useless to go — is frequently much exceeded in l):i(l cases. Respiratory System. Bathing modifies the respiratory act in a similar way to the pulse, but to a less extent. When the short, catchy breathing, due to the shock of immersion, has passed off, the respirations become slower and deepQr. If bronchial catarrh is present, cough is invariable, and sometimes violent. This is most beneficial ; and in consequence, it is found that soon after the couniiencement of the treatment, the patient coughs only during the bath, although [)reviously he may have been troubled with constant and ineffectual efforts to clear the bronchial tubes. The i)eriodic clearing of the air {)as.sages prevents plugging and collapse, and the consequent gradual development of broncho-pneumonia. No fact is more firmly established about this treatment, than its power to prevent this complication. Whether it is advisable to continue cold bathing when ])neumonia is actually present, will depend altogether upon the condition of the circulation. In my experience, more or less cardiac feebleness almost always co-exists, and this I believe to be the best guide, without taking into considei'ation the condition of the lungs. Rarely a pneumonia, usually lobar in form, complicates, or even masks, the beginning of typhoid. It may then be unattended by any degree of cardiac debility, and is decidedly benefited by the bath treatment. On the other hand, the usual form of pneumonia, which appears in the later stages of the disease, is lobular or hypostatic. Ic is then probably one of the immediate results of failing circulation, and when it occurs in cases that have been bathed, should in my opinion be accepted as an indication that the treatment has failed, at any rate, in its i)rimary object, viz., that of preventing cardiac debility. If under these circumstances baths are still considered advisable, they should be tepid or graduated, so as avoid all shock. Nervous System. Nervous symi)toms are probably more favourably influenced than any others. Delirium and stupor frequently disappear in the first bath, almost always after the first few days' treatment. Headache is always relieved, but returns with the rise of temperature. Sometimes the immediate result of the bath is to increase the pain, but this can always be avoided, by sponging the head with ice cold water before the rest of the body is immersed. Insomnia is almost unknown. Most patients require to be waked for their baths, and I would here say that, although such frequent dis- turbance may seem cruel, the aggregate of sleep that such patients obtain is far greater than in those treated in the ordinary way. The density of the sleeji, if I may use the expression, is greatest shortly after the bath, and gradually decreases as the temperature rises. 182 ixtekcolonial medical congress of australasia. Alimentary Canal. Symptoms having reference to the alimentary canal are all more or less modified; sordes rarely appears. Tlie dry brown tongue, when it is seen at all, becomes moist after each bath ; thirst is consequently lessened and appetite improved, and herein lies the great advantage of always giving food at this time. So great is the influence of the bath in this direction, that one may often see a dry Ijrown tongue put in its first appearance during early convalescence, when, from the falling temperature, it has become unnecessary to continue the treatment. Although it may not be permissible to judge of the condition of the gastric mucous membrane by that of the tongue, yet it is certain that digestion in the stomach is much improved. Vomiting is rare, and the appeai-ance of undigested milk in the stools quite exceptional. Diarrhoea, if it exists on admission, often appears at first sight to be increased. The application of cold to the abdomen causes contraction of the muscular fibres of the intestine, so that for some time a patient may have an evacuation after each bath. This, however, soon ceases. It has been said that external cold, by contracting the cutaneous vessels, must cause an increased congestion of internal organs, and among them of the mucous coat of the intestines. This has Ijeen disproved by actual experiment, but were it not so, the fact remains that the constant application of cold to the abdomen, preferably in the form of ice bags, has a marked influence in restraining diarrhoea, and presumably therefore, in diminishing the congestion on which it depends. The constrictive action of cold on the intestinal muscle is most useful in lessening meteorism. As the flatus is mostly contained in the large intestine, the efiect is usually immediate, the patient passing large quantities of wind during or immediately after each bath. Ice bags applied to the abdomen in the interim keep up a tonic contraction of the gut, and serve to prevent the reaccumulation of the gas. Haemorrhage, as before mentioned, precludes bathing. Ice bags should be applied locally, and are in fact in general use. Whether this accident has been rendered more or less frequent by the cold bath system, has been much debated. My own figures tend to the conclusion that it is absolutely uninfluenced either way. The same i-emarks apply to ])erforation, which, as the mortality statistics show, carries off almost exactly the same number of patients whatever treatment be adopted. There is, however, an interesting fact in connection with the diagnosis of perforation which is worthy of note, as it bears additional evidence to the rarity of brain symptoms. Since the introduction of systematic bathing, there has been no instance where it has not been possible to tell almost the exact moment when this accident occurred. This is in striking contrast to what was observed previously. Low forms of delirium and stupor were common, and it was not rare to find perforative peritonitis post-mortem, Avhich had been unsus])ected during life. Urinary System. The effect of bathing on the urinary secretion, is greatly to increase its quantity and to lower its specific gravity. The total amount of urea passed is said to be reduced, and this is attributed to diminished febrile consumption of the tissues. THE COLD BATH TREATMENT OF TYPHOID FEVEH. 183 Upon this point, liowever, I have no data of my own, and the state- ments of other observers are conflicting. Recently, indeed, ex]ieriments have been cited, which tend to show tliat the excretion of urea is increased by cold bathing ; and Dr. Macalister suggests that this is not due to increased production, but rather to more perfect elimination. If albumen be present in small quantities, as often happens in severe cases, in connection with a .scanty secretion of high coloured urine, a day or two of the treatment is usually sufficient to cause its disappear- ance. The action of the bath, in causing prof use diuresis, contrasts ^"ery favourably with that of the antipyretic drugs, none of which increase the secretion of the urine. Some, indeed, notably anti})yrin, have been shown to actually diminish it. My own experience is, that they all act as powerful diaphoretics, and herein lies one of the great advantages of the bath ; for, as has been duly remarked, the sweat glands, as organs of <'limination, cannot be compared to the kidneys. Such, then, is a brief account of the manner in which the cold bath treatment modifies the principal symptoms of fever. It is no exaggera- tion to say, that typhoid so treated is in its main clinical features a ditl'erent disease, and as such merits a separate description. Instead of the long catalogue of complications, with pneumonia at their head, that wei-e liable to arise in any case of severity, it can be truly said that, given a case admitted fairly early in the disease, one has little to fear, except the occurrence of one of the accidents — haemorrhage or perfora- tion. Before estimating the mortality, some explanation is required. During the year 1886, the bath was used in only one or two cases. The treatment was mainly ex]iectant, but cold sponging, the cold wet .sheet, and quinine in antipyretic doses, were frequently employed, together with alcohol, according to the usual indications. In 1887, every case that was admitted on and after January 1st, Avas systematically bathed; unless, of course, this was contra-indicated. Owing, however, to the fact that there was then only one bath, and the wards were quite full, the bathing, though regular, was infrequent. Many patients who would later on have had six or eight baths a day, had then only three or four. It was not until July that arrangements were suffi- ciently advanced to allow of Brand's rule being strictly adhered to. I propose, however, to compare the mortality of 1886 with that of the following eighteen months, ending June 30th, 1888, the latter being the whole j^eriod during which the bath has been in systematic use. In doing this, I have made an endeavour to eliminate one common source of fallacy in fever statistics. I allude to the variable number of cases of febricula included. No two men are agreed as to where to draw the line between this afTection and ty])hoid. I have accordingly adopted an arbitrary rule, and classed as febricula all cases of continued fever that convalesced before the tenth day. 78 such cases, or 14| per cent, of the whole, are excluded from the first period ; and 73, or 15 per cent, of the whole, from the second ^Nlost of these were, in my opinion, typhoid, and many were bathed. The\' all, of course, recovered. In the first ])eriod then, there were 464 cases, with 68 deaths — a mortality of 14-6 })er cent. In the second, 415 cases, with 41 deaths — a mortality of 9-8 per cent. So that during the time that the bath was in use, the mortality fell 184 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. nearly 5 per cent. If, however, we take the twelve months, from July 1st 1887, to June 30th, 1888, during which Brand's treatment was rigidly enforced, we find better results. Of 243 cases, 20 died-^— a mortality of 8 '2 per cent. This shows a reduction of mortality, as compared with 1886, of 6-4 i^er cent. These figures appear to me sufficiently favourable, but to give them their full weight, the following considerations must be borne in mind : — (1) That a very large proportion of the cases were immigrants just arrived in the colony, and unacclimatised. Tliis is admittedly an unfavourable element in the prognosis. (2) That the Brisbane Hospital is the only one for a large and scattei'ed district ; that the cases there- fore are not selected, except in so far that the worst generally find their way in. (3) While an unusually large proportion of febriculte (15 jter cent.) are excluded, that on the other hand, every death from typhoid, which occurred in the hospital during the time, is included, though many were moribund on admission, and others succumbed from causes only indirectly due to the disease. Thus of the 41 deaths during the bath period, five died in less than 48 hours from admission; and six, who came in later in the disease than the fourth week, were in such an advanced state of prostration, that cold bathing was considered inadmissible ; whilst, among the exceptional causesof death were — hyemorrhage from abortion; hyper-pyrexia following an ineffectual attempt to pass a catheter on a case of tight stricture during early convalescence ; old fatty heart ; and acute cystitis during convalescence — one case of each. I do not think these results can be explained on the hypothesis, that the type of the disease was milder. The average duration of cases that recovered was almost identical in both periods, viz., 23'1 days in the first, 23-2 in the second, and nearly the same proportion of febriculte were excluded upon each, i-ather more in fact from the second. Moreover, a strong argument in favour of the identity of the type of the disease in the two periods, is found on analysing the modes of death. Of the 14-6 mortality in 1886, 5*2 per cent, of all the cases died from hoemorrhage or perforation. During the bathing period, of the 9-8 per cent, mortality, perforation and haemorrhage accounted for 5-5. It is evident, therefore, that the accidents due to the intestinal ulceration were absolutely unaffected, and that the whole saving was in the diminished number of deaths due to febrile causes. Exactly the same conclusions were arrived at by Drs. Cayley and Coupland, at the Middlesex Hospital. These observers contrasted the results obtained, during the period from 1872-78 inclusive, with those of the following five yeai-s, during which the antipyretic treatment was practised. By comparing the total number of cases under treatment, they found that the rate per cent, of deaths from hajmorrhage and perforation was almost exactly the same in the two series, showing that there was a diminution of the other causes, but no inci'ease of these complications. Again, since of these two accidents, perforation claims many more victims than haemorrhage, and as it is an established fact, that the former is far more common in men than women, we should expect to find the female mortality more favourably affected than the male — and this has been the case to a marked degree. In the fii'st period, the male mortality ox -n'PlIOID FEVER AXD ITS TREATMEXT. 185 was 12-G per cent, the feinalo lS-9. In the second, the male 12-2, the female O"!. On analysing the causes of death, this result is found to be entirely due to the coin])arative immunity of women from perforation. I should here say that in the 109 fatal cases, the immediate cause of death was verified by post-mortem examination in all but live. I have hitherto avoided discussing the rationale of the bath treatment. Its original introduction into Germany was the practical outcome of the theory, that the temperature was the immediate cause of most of the symptoms and complications of the disease. Of late years, the truth of this has been much questioned, and yet those who are foremost in attacking the doctrine, admit that cold baths deserve the first place among the thei-apeutics of fevei'. Quite recently Dr. Macalister, in his Ci'oonian Lectures on Anti})yi-etics, recalls the theory of Murchison, that most of the phenomena of the typhoid state are urtenuc in origin, and suggests that the benefit of the cold bath is due to its powerful diuretic action, causing free elimination of accumulated waste nitrogenous products. The beneficial action of cold bathing can be undei'stood on this hypothesis, as well as on the other, and it is jjrobable there is much truth in both. But neither are sufficient. Delirium and stupor occasionally clear up too rapidly to be accounted for, either by reduction of tempei-ature, or improvement in the composition of the blood, so that it is evident that any theory, to be complete, must include a more direct action on the central nervous system. All these, however, are questions for ]iathologists to decide. Fortunately, the success of the treatment is not dependent on their correct solution, but rests at the present day upon a vast accumulation of clinical facts. In conclusion, I must allude to a recent valuable monogra})h on the subject, by MM. Tripier and Bonveret, of Lyons, which all who are interested in this method of treatment should read. In this work, the whole question is treated with such minute attention to clinical detail, that I regret it did not fall into my hands until the latter part of 1887, when the system was fairly well established. Otherwise, much needless trouble and anxiety on my part might have been avoided. XOTES ON TYPHOID AND ITS TREATMENT. By F. H. BoNXEFix, L.R.C.P., Stockton, Newcastle, N.8.W. In tlie present state of medical science, we must confess that know- ledge about the etiology and treatment of typhoid fever is still very imperfect. For whilst some hold that typhoid fever (or better, enteric fever) is a specific disease, produced by a bacillus or its spores, and that the disease cannot arise de novo ; others assert that, though the disease is due to micro-organisms, yet it can arise de novi by the transformation of ordinary bacilli into a virulent variety. There is still another sect who hold that enteric fever may, undoul)tedly, arise from deconq)Osing animal matter, placed under certain conditions of heat and moisture. All the above theories tend to .show that the subject is far from l)eing settled, and therefoi'e, anyone holding views on the subject, not incon- sistent with reason, and arrived at by scientific deductions, may claim 186 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. also to have a hearing. AV^hatever may be the cause of typhoid, all agree on the pathological lesions, which are characteristic. In all cases the small intestine is affected, but more specially the glandular structures known as Peyer's patches, and the solitary glands. In them, we may find .simple inflammation, or proceeding one step further, necrosis of the tissues and iilceration. The real use of Peyer's patches and solitary glands has not yet been cleai'ly defined, and when this is perfectly demonstrated, I am certain that a very great step will have been made towards the knowledge of the disease. I will now briefly state my views, ho])ing that by inducing criticism, more thought and discussion may be excited on a subject of vital importance in these colonies. I have always thought that enteric fever was symptomatic, and not idiopathic. A good many of the fevers, which were formerly classed under the heading of idiopathic fevers, have, in the light of more recent knowledge, been proved to be pyrexiie, caused by acute inflammation in some part of the organism. Why, therefore, should we not consider enteric fever as a pyrexia, caused by in- flammation of certain specified structures of the body, to wit, Peyer's patches and the solitary glands. It is certain to be objected, that the height of tlie pyrexia has been proved not to depend absolutely on the amount of the lesions observed. But it may very well be in direct proportion to the absorption of inflammatory or septic products ; and knowing that the implicated structures are in direct communication with large lymph spaces, is there any wonder that absorption is simply regulated by the blocking oi- patency of such spaces 1 The rise and fall of temperature is ver}' often typical, and we may understand why it is more so in this than in other fevers, if we bear in mind that absorption is generally more active when the circulation is more rapid, and this is more the case with lymphoid structures and lymphatics generally, than with any other tissue or organs in the body. The morning temperature of enteric is generally lower, because the circulation at night is slower, and therefore the absorption of inflamma- tory or septic products is less. In that way, the tem})erature gradually falls during the night, and again rises during the day. It is generally considered as a bad sign, when the morning temperature is not lower than it was the previous evening ; this shows, either the patient has been sleepless, or has had very troubled sleep, and so, the absor})tion going on uniformly, the intensity of the malady is increased. It is on the foregoing assum])tions that I have based my treatment of enteric. What I wanted to use was some medicinal agent, which could at the same time slacken the circulation, cause elimination of efl'ete and noxious substances, disinfect the contents of the bowels, promote the healing of ulcers, or check inflammation, without causing distressing symptoms, as very often is the case with quinine and salicylic acid. I need not give in detail my difi"erent trials in this direction, but will simply state that, since the second part of 1887, I have used the following ; — I give a mixture of naphthalin and antifebrin (gr. vi.-viii. of each), three or four times a day, according to the urgency of symptoms. Should there be consti[)ation, I get the bowels moved at least once a day by means of a simple enema, or one containing a little starch, soap, or castor oil. I draw special attention to this measure, for I have found naphthalin of little use xuiless the bowels are moved, so as to allow of ON TYPHOID FEVER AND ITS TREATMENT. 187 the local eftect of the drug. Intense diarrhoea also must be checked, as it does not allow the naphthalin to act beneficially. I ordei' such diet as will not produce much faecal matter, or form any solid or irritating material ; so I prefer a mixture of milk and barley water, in equal projiortions, or some chicken or veal broth. Sometimes concentrated beef tea is too irritating. The average duration of cases has been under fourteen days, and this year it has come down to twelve days. I hope that this treatment may be given a trial, for the results in my hands have been very good. Since I have adopted it, I have lost only one case, and this under the following circumstances : — Mrs. R., aged about 30, just returned from England, began to show signs of enteric fever the day after landing. Saw her two days after, when she had a temperature of 104", bad headache, and all the other signs of enteric fever. I was using then the antipyrin-naphthalin treatment, instead of antifebrin-naphthalin. In eight days the patient said she felt entirely well, and the temperature remained normal for twenty- four hours. I asked her to be careful, notwithstanding, and go on with the milk and barley water diet, and remain in bed. I had scarcely left her place before she partook of a heavy meal, composed of roast mutton, boiled potatoes, cabbage, and beer. Half an hour later, she was taken with intense vomiting and griping pains. The temperature the next day, when I saw her, had run up to 104"8\ By energetic measures, and same treatment as before, I succeeded in getting her right again about six days after. I told her that she must be more careful this time, but it was all to no purpose, as she left her house this same afternoon for a walk by the seaside, and was found there and brought home in a very weak state. She died two days after, all my efforts this time being unavailing. I should have stated that, before employing the naphthalin-antifebrin treatment, I had recourse to antipyrin and naphthalin for nearly a year, but that I adopted antifebrin as being safer, and causing greater elimina- tion of effete products, whilst at the same time I found that its antipyretic effects lasted longer. The naphthalin and antifebrin are ground into an impalpable powder, and administered as such. [Appended to Dr. Bonnefin's ])aper were notes of ten cases, illustrating the course and termination under the treatment recommended.] 188 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. DISCUSSION ON TYPHOID. The Chairman, when calling on Members to take part in the discussion, said that, on account of the time which had been given to the reading of papers, it would be necessary to confine remarks made to points connected with the etiology of typhoid. Dr. Whittell said : — It has been my duty during tlie last five and a half years, in connection with the Central Board of Health of South Australia, to pay particular attention to the etiology of typhoid fever — to the origin of cases in South Australia, to their mode of progression, and to the best means by which we were able to put a stop to the pro- gress of different outbreaks that have occurred during that ))eriod. From my ex])erience, and from my experiments in bacteriology, I have arrived at pretty much the same conclusions as were arrived at hj Dr. Carstairs, in the paper which he has read to us. 1 believe that typhoid fever is due to a bacillus of a specific character, always the same bacillus, and that that bacillus proi)agates itself partly in the bodies of the persons affected, and jiartly in the various materials with which it may be brought into contact, after it has passed through the body in the evacuations. It is very important that we should have a fixed notion about this bacillus and it habits, and the means by which it is propa- gated. Proljably, we shall have to take many yeai'S in the study of the bacillus, before we shall know all about the etiology of typhoid fever ; but thus far, all pathologists have arrived I think at the conclusion, that the bacillus passes in the dejecta of the patients, and that it may be carried away in various modes. It may propagate itself in those waste matters which are too frequently allowed to surround houses ; may be carried into our water at long distances from where it was originally deposited; may contaminate our milk supplies, owing to the negligence of milk sellers, and the want of laws to regulate them and their dairies ; and, I believe, too, although it would be disputed by a good many people, that it may be disseminated through the air. I will just mention some three or four outbreaks, in vi^hich I have been personally interested, during the time I have occupied the position in connection with the Board of Health in South Austi-alia. During that time, I have had personally to investigate two cases, where undoubtedly the outbreak of the disease amongst the people was due to milk. In one case, after a good deal of troublesome inquiry, in which we were resisted by the dairyman in all directions, and told there was no disease in the man's house, although we had traced, as we believed, several cases of tyj)hoid fever to the milk he had supplied, we succeeded in finding that there had been a case of typhoid fever in the house, and that when the medical officer went down to inquire into the history of the case, the patient, wjio was then convalescent, had been hidden away from the sight of the medical practitioner — ])ositively hidden amongst the milk cans in the dairy behind. I had a good deal of difficulty with that dairyman, he defied me, he said he would not stop the sale of milk, or sell the cows, or do anything he had not already done. However by a threat, that if another case of ty[)hoid fever should occur in connection with any of his customers, I should certainly call on the Coroner to hold an investigation, i DISCUSSION ON TYPHOID. 189 I succeeded in inducing him to remove the cows, and ])lace them under the care of persons who had not been in contact with this typhoid fever patient, and by that means we succeeded in arresting that epidemic. I had another simihir case, where, after investigation, we found a boy who had l)een undoubtedly affected by fever, and had been nursed by his mother and friends, who had had the handling of the milk cans, and of the various dairy utensils. These cases illustrated well enough to me, and to any one acquainted with their history, how typhoid may be con- veyed through milk, to ])ersons living in houses where everything that is desirable, so far as regards sanitary arrangements, is to be found. Now with regard to water ; we know that French practitioners of late days have nearly all come to the conclusion, that typhoid is ])ropagated chiefly by water. In Melbourne, where there is a water supply like the Yan Yean, which I am told by competent authorities is pretty fair, though it has a few faults that must be corrected, but which on the whole is of a very fair, good, and wholesome quality ; or in a place like Adelaide, which also has a very good water supj)ly, it is difficult to understand how the water can be a source of tyjihoid fever. S{)eaking as to our own towns in South Austi'alia, and I think I may say the same of Melbourne and its suburbs, I do not believe that the water su])ply has anything to do with the typhoid cases. Still, we know that water will become con- taminated, and may be a source of conveyance of the typhoid microbe. I have seen cases where that undoubtedly has been the case, and one of these was just outside Adelaide, where, owing to the wells supplying the household water being near the cesspools, there was an undoubted con- tamination, detectibie by smell, caused by the passage of faecal matter from those cesspools into the wells. Dr. Jamieson said that it might be interesting, so far as Melbourne is specially concerned, that he should say a few words about what he had seen and known, and try to sum up some facts as to the spread of the disease in the city, and the causes of that spread. Before going further, he would like to draw attention to a chart, which illustrated in a graphic way the prevalence of typhoid in Melbourne and suburbs, during a period of 23 years, from 1866 to 1888. The ])articular point to be noted is, that at periods recurring with great regularity, at intervals of four years, the mortality from typhoid attains a maximum, and then subsides. The curves were based, not of course on the absolute number of cases, which would be fallacious in a rapidly growing town, but on the pro- portion per hundred thousand of the inhabitants. Tliis fact should be kept in view, in reference to all questions of causation, which would have to be tested to some extent by the comparative prevalence of disease. As to the probable causes of the spread of the disease in Mel- bourne, of course it is clear, as everyone knows, that in a large city there must be always special difficulties in inquiring into the occurrence of cases, how they come about, and why they spread. About the special causes that are always adduced, he might refer first to the water supply. In regard to that point, already mentioned by Dr. Whittell, he could not believe that the contamination of the Yan Yean water su])ply has any appreciable effect in spreading typhoid in this city. Even if there is a possibility of an occasional contamination of that water, the possible sources of contamination are so small and scattered, that such eontamination could be only a comparatively rare event. It seemed 190 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. inconceivable that contamination of that water sup]jly, which is dis- tributed all over the town, if it were an important cause, would allow of the disease beginning, with some severity, in November, and increasing in January, February, March, April, and May, year after year. If the contamination of the water supi)ly had much to do with it, the out- breaks ought to be in great epidemics, and then stop ; but year after year it goes on in the same way. The next question is as to milk, how far that may be supposed to have much to do with the spread of disease in tliis town. He did not question at all the probability that milk does get contaminated, and is distributed in Melbourne, and causes typhoid ; he did not question the validity of the argument that Professor Allen adduced. He was acquainted with the Jolimont outbreak referred to, and was prepared to believe that milk was the cause of the spread of typhoid at the time, but the same argument must be applied to milk as to water. It was not easy to see why milk should go on year after year causing this regular rise and decline of typhoid. As to specific ex- perience, he could say that during the years 1887-8, he had occasion to inquire officially, as health officer, into this milk question in relation to typhoid. And though he had started witli the expectation of finding a connection, he had not been able to put his finger on one single instance, in which he was satisfied that milk had been the cause of the spread of the disease. Then, what are the causes? There remains the di-ainage ; there remains nightsoil disposal, especially. It could not be questioned at all, that Melbourne is an excessively badly drained cit}'. The most recent visitor must have seen the foul water trickling slowly along, never reaching its destination, unless that destination is to sink below the surface. In the course of enquiries, he had made this distinct observa- tion repeatedly, that where serious outbreaks of typhoid occurred, it could almost regularly be shown that it was usually in a crowded or badly drained locality. Not long ago, Dr. Simpson, the Health Officer of Calcutta, was here, and having made the remark, " I have seen the good streets of Melbourne, the fair side of Melboiirne, can you show me the other side?" He (Dr. Jamieson) took him to places where cases of typhoid occurred, which he attributed to soakage of foul water round the houses. After visiting a number of these localities, Dr. Simpson was satisfied that the cause of the outbreak was to be found in the fact, that the water had been soaking down to these houses on the low level ; that they got it, and with it the typhoid. Of coui'se, we must admit that the mere soakage of foul water will not do it, that goes on all over the world ; but if you get that, and a sj^ecific infecting material, you are bound to get typhoid largely. He would like to narrate a curious instance that came under his notice within a few days before, illustrat- ing the influence of a bad arrangement for the disposal of nightsoil, and with it, the neglect of precautions. The medical man attending a patient reported that there was a case of tyjihoid in a certain house. There were two children ill in the house at that time, but there had been a ])revious case six weeks before. On visiting tlie house, he learned that tlicrc had been expended, one tin of carbolic powder and one little bottle of Condy's fluid, which had been spread about the house in saucers. That several cases should occur in such a house was to be expected. But the matter did not end there. The closet belonging to this house, in which those three cases had occurred, had been pushed away, naturally enough, DISCUSSION 0\ TYPHOID. 191 from the people's own lionse, and made to abut on the fence of another Iiouse, so that tlie back wall of the closet actually formed part of the fence. There was no communication between the houses, which faced to diderent streets. About the same time that the two cases occurred in the first house, two children in the other house got the disease, and both died. There was no absolute proof that these fatal cases were caused by the emanations from that closet, but it looked like a deliberately arranged experiment to prove that nightsoil, not properly dealt with, will cause the spread of typhoid. Those were the two points lie wished specially to bring out. Dr. Leger Ei!S0X said that, having come recently from Auckland, where there was a great deal of typhoid, he was deeply interested in the discussion. The question had been raised, whether typhoid can arise de novo. He had seen cases in the bush, where there had been no ty])hoid ; no history of any within the memory of Maori or white man — cases where one, two, or three children had been affected from a distinct source of causation — merely some putrid animal matter lying about where the children played. He had also seen typhoid occur on board' ship, when three months out at sea. Where was the previous source of causation there ■? He made inquiries, and came to the conclusion that it came from neglected bilge water, no cases liavin^ occurred in the ship before. In towns, there was often a mistake in getting an artificial water supply, without a single thought given as to the disposal of sewage, though they should go together. He had remarked that in Melbourne there was a system of earth closets where no earth was used, and that is an important point in the causation of typhoid. Even in Fiji they are more advanced in sanitation than we are. There they have a man inspecting the closets, and if the earth is not used, a heavy fine is inflicted. That was a suggestion for adoption in Melbourne. Dr. IviRTiKAR (of Bombay) said that it would be of some interest to the members of this Congress to know what was thought of typhoid fever in India. The late sanitary commis.sioner of Bombay (Dr. Hewlett), said that the natives of India are born in filth, brought up in filth, and die in filth ! Of course there will be very few who wnll accept this wholesale condemnation of India, but there is a good deal of truth in it. There is a good deal of filth around us ; a good deal of cholera around us; a good deal of malaria around us. There are all sorts of malarial fever — intermittent, quotidian, quartan, tertian, and a very terrible form of remittent fever. Well now, this remittent fever, to a certain extent, corresponds with the typhoid fever of Europe and of this country, but the true typhoid fever is said to be almost absent. It is found to prevail among European troops alone, and among Europeans arriving in India. It is scarcely seen amongst natives. The army doctors of the British medical service all combine in thinking that the members of the Indian medical service are not able to diagnose typhoid fever among the natives, but we think we ought to know something of the diseases prevalent among the natives of India, as we have the whole field of medical practice in India to ourselves. The British army doctors think we make a mistake in not diagnosing more cases of typhoid in India ; but as a student of bacteriology — that large department of science — I consider that, although we have remittent 192 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. fever, Avith diarrhcea very often fatal, the absence of tyi)lioid is a very signiiicant fact. Tliere is a something in typhoid that has a particular cause — a special germ — which as yet has not been able to find a congenial soil in India. Now, it is for me and others in India, who work in the field of bacteriology, to find out hereafter, from what I learn from you here, whether there are any special circumstances in this colony causing typhoid, which are absent in India, and vice versd ; and it will be an impoi'tant lesson for us to leai-n that mere filth cannot cause typhoid. I am sure this consideration will afford an interesting field for further investigation. But there is one point which I Avant to bring before this Congress, with reference to the ])articular form of remittent fever we have in Bombay. There is a kind of fever that corresponds with typhoid fever, but there are certain points of difference. We have the remittent fever, which lasts very often over twenty-one days ; there is the remission, the morning remission, and the evening rise, but it is not the remission of typhoid fever. There is a kind of diarrhoea present sometimes, though very often it is absent. Where the diarrhoea exists there are stools, very nearly allied to the " pea-soupy " stools of true tyjihoid. We have occasionally haamoirhagic patches under the skin, corresponding to those in real typhoid. We have also, when vv^e come to study the ])athology of the intestinal tract, the Pej'erian patches also affected, but not to the same extent. Strangely enough, in this particular kind of fever, the secreting glands of the wall of the intestinal tract are attacked, swollen and fringed. The mesenteric glands not so largely and so early implicated as in true typhoid. These pathological a|)pearances show some kind of connection between the typhoid fever you find here, and the septic Bombay fever I am describing, and a careless observer is liable to mistake the post-mortem appearances of the one for the other. It will afford an interesting field for research to pursue the pathology of this Bombay fever. In 18S6, Dr. Vandyke Carter first directed our attention to the Peyerian ulcer lesion found in the remittent fever of Bombay, attended with diarrhoea and simulating typhoid. It will be my pleasure, when I return to India, to send to the Medical Society here, and to any other society in the colonies which the Secretary informs me about, copies of the Transactions of the Bombay Medical and Physical Societ)^ for your information — Transactions in which Dr. Carter gives us his first instalment of researches on fever with Peyerinn lesion — in order that you may be able to know that, although in India we have no typhoid, we have this particular kind of i-emittent fever which is the scourge of the Indian peasant, as also the Indian citizen. It is a terrible disease, and its origin can be traced to sej)tic poisoning from filth. The great danger from typhoid, as far as I know from my books, and as far as I learnt as a student in England, is pneumonic complications, and complications especially connected with the heart, as Professor Allen has just told us; but in India, this remittent fever is very often complicated with bi^ain symptoms, and we have what they call " the brain fever." This form of fever in Bombay is particularly dangerous in the earliest stages, the ninth day being the most dangei-ous. We know that even in its early stages, typlioid is very dangerous. In some cases, the person is actually bowled over long before the stage of diarrhoea sets in, or petechiie appear. So far, the two fevers resemble i DISCUSSION OX TYPHOID. 193 cacli other ; but on the otliei- huiid, in the Bombay remittent fever, we have a special kind of pathological and final result, which is not quite characteristic of typhoid. Dr. Newmax said that it was important to note the variation of the type of the disease in this country. It is altogether different in some respects from typhoid fever in the old country. Very rarely we have diarrhcea, but we have constipation ; and as to spots, we often do not see a sign of them. About the variations of typhoid disease, we find in some epidemics we get nothing but head symptoms, and in others troubles connected with the bowels, though not necessarily diarrluea, and even we get sometimes haemorrhage in the bowels, with the con- stipation. I tliink there must be something different in the typhoid fever in these colonies from that at home, or we would not have such remark- able changes. . Dr. Ellis (Sydney), said : — We have all been talking about germs, and I do not know how many here have studied them scientifically. Tliere seems to be an idea that if one germ gets in, it causes tyj)hoid fe\ er. The great question is, the quantity of germs necessary to cause typhoid. Some people have taken in a certain amount of germs, and not got it, and a great deal dejjeuds on the dilution. Ordinary tilth, by standing, does not cause it, or it would be mucli more common than it is. The question is — How far does the filth hel]) the germination, so that they can come together in large quantities, sufficient to attack the individual, and cause typhoid fever ? and on this point I lay stress as to milk. I think if you get contaminated milk, and let it stand for some time at a certain temperature, you will very greatly increase the probability of giving typhoid fever to those j)eoi)le who drink it. The ordinary process of scalding it does not sterilize the spores ; you must steam it for ten or twelve minutes, and less injury is done to the milk in that way than any other. This especially a])plies to milk for children. As to the use of filters, the ordinary filters are perfectly useless — the only one I know of that is any use is Chamberlain's. I made some cultivation experi- ments with those. I took some water from an ordinary tap in Sydney, and found that it had 30 germs to the cubic centimetre. I took the water from the Chamberlain filter, which had no germs, but I passed the water through that, and then through my own filter, which I had been using, and after that I found 300 germs to the cubic centimetre. Sup- j>osing your filter got contaminated in this way, you simply have the ground for growing the typhoid germs. I do not think it is conceivable, to any person who has studied germs, that it is possible for the typhoid germs to be developed out of any other germ ; but where the tjphoid germ gets into ground that is jirepared for its propagation, it will develop rapidly. There is another point. The ordinary idea as to rendering the stools aseptic in the ordinary way, is by adding a small amount of carbolic acid or corrosive sublimate. You may do a great deal more harm than good. That is a very curious statement, but it is true all the same. You will find generally — I do not know that it holds exactly with tyjihoid — that the poisons and ptomaines generated with the ordinary putrefaction, are very deadly to the ordinary fever germs ; but the ptomaines are more easily prevented from growing than the fe\"er germs, and if you put a small amount of antiseptic into the stools, you will o 194 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. prevent the ptomaines generating, whereas you give a splendid oppor- tunity for the typhoid germs to develop, especially if a little later ou the matter gets spread over the soil. Dr. Bright (Hobart) said : — I think I can throw a little light on the subject of typhoid. In regard to the paper read by Di-. Robertson, 1 wish to say I know a few facts that do not quite coincide with some of the statements he made. He told us that typhoid is not conveyed from the sick to the healthy. I am sorry to say I have had pretty strong proof that it is. J have seen a good deal of typhoid fever the last twenty-tive years; but within the last two years at Hobart, at the hospital of which I am one of the staff', we have had 500 cases — 200 last summer, and 300 the year before. Fully a fourth of those cases had to pass under my hands. Thex'e we found a large number of our nurses were knocked up by nursing the sick ; and it goes to contiadict another statement of Dr. Robertson's — that recent stools are not in- fectious, but they must be first fermented. I think they are infectious from the first, and I believe it was in that way the nurses in the Hobart Hospital became knocked over with fever in the way they were ; and when we found they were being made so ill, we began to look carefully into it, and we found that from ihe number of cases they had to look after, the practice of removing the bed-pans was rather lax. The pans were not sufficiently disinfected, and not covered over when they had to be carried a short distance from the wai'ds ; and sometimes this was done at once, the same as an ordinary stool might be. When we found this out, we insisted on disinfectants being used, and had the pans covered, and after that the nurses ceased to be affected. That goes to show that recent stools are infectious. Then Dr. Robertson told us that one attack gives immunity from future attacks. I am sorry to say I have had positive proof that that is not the case. I attended a patient three or four years ago for a moderate attack of typhoid ; there were spots and all the ordinary symptoms, and last year I attended him for a more severe attack. As to the SjU'ead of typhoid, the conviction has been forced upon me that hospital patients, after they have left the hospital, and are supjiosed to be convalescent from typhoid, are capable of spreading typhoid among the healthy. Numbers of ])atients have left the hospital, after recovery from typhoid ; not in one, two, or three, but in a good many instances, we have had cases come back again from other members of the family a few weeks after they have gone home, where there was no typhoid previously in their houses. I have known typhoid patients, who have been asked to stay in houses in the country to regain their strength, and typhoid has broken out after they have gone there ; so I am fully convinced that typlioid ))atients, for some weeks after their recovery, are rather dangerous pei'sons to have about liouses, unless precautions are taken to disinfect their stools, the same as when they are suffering from the fever. In order to prevent the tyjihoid, the stools of convalescents should be disinfected, for at least three weeks after they are supposed to be quite well. Professor Kernot, speaking by ])ermission, as a member of the Central Board of Health, desired to raise the question of the best kind of channels. Lai'ge towns might be ]iroperly sewered, but small towns would have to dejjend on surface di'ainage. DISCUSSIOX ON TYPHOID. 195 The Chairman, in t-lossing tlie discussion, regi-etted tliat the time had been so sliort tliat tlie gentlemen wlio si)oke did not speak as fully as they might have wished, and that others had no o[)[)Oitiinity to speak at all. We all agree, no matter how much we may disagree as to how typhoid is jirodiiced (whether it can be produced hers between a technique or art of which certain rules were to V)e put in practice, and a science which, by a series of inductions or deductions, enunciated certain propositions showing on what 200 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. conditions the effect, which the art aims at producing, depends. While as an art, surgery, as well as medicine, long remained a calling apart -not always one of honour — as a science, its progress soon "became inseparably connected with that of physiology or biology. Hence, its scientific history is that of the biological sciences, and surgery is scientific only as biology is scientific. To an English physician, largely influenced no doubt by his Italian teaching, we owe the discovery of that, which is alike the starting point of scientific physiology and the central factor of practical surgery, viz., the cii-culation of the blood ; but it is not a little remarkable, that that great and potent factor in sui-gery, the ligature, dates from a period a hundred years before Harvey's great discovery, a conspicuous example of the potential value of an isolated and empirical fact. And, j'et again, in the use of anaesthetics, we have another such example of how prodigious and unexpected may be the influence exerted Ijy ])urely accidental discoveries. Remove these two i)illars of our craft, the ligature and the anaesthetic, and how much of the modern edifice of surgery would crumble down. So, too, who would have anticipated, in the early investigations and discoveries of Leeuwenhoek and Ehrenberg into microscopic organisms, the seed of that rich harvest which is now being reached in the application of theories of germs and of })utrefactiou not only to surgery, but to medicine, sanitary science, the economics of food and drink, and to many of our staple industries. Such illustrations as these, which accentuate the influence of isolated facts upon the progress of surgery, may seem to be contradictory to my general contention for the greater importance of scientific theories, but it is not really so. As an art, no doubt, surgery has been largely benefited by empirical discovei-ies ; but qud science, isolated facts — and the above are no exception to the rule — have no real and enduring value until their relations are determined and brought under the scope of general laws. Ambrose Pare, we have reason to believe, " attached a higher value to the efficacy of a /rt?-;T///o of boiled pupi)y-dog and earth-worms pickled in white wine as a cure for gunshot wounds — to learn the secret of which we are told he ])aid two yeai's' court to a surgeon of Turin- — ■ than he did to the ligature;" and until the fact of the ligature came to be fitted in with the theory of the circulation, its use could only have been a subordinate factor in the art of surgery, and of next to no account in the science of disease. Tiie anaesthetic projjerties of various drugs have been known as facts from the time of the Egyptians, l)ut until it was perceived that in- sensil)ility and the relief of pain might be made applicable to surgical procedures, and become closely related to their results, these were regarded as drugs more curious than useful ; and so also, the early in- PRESIDENTS ADDRESS — SECTION OF SUKOERY. 201 vestigations into niici'oscopic organisms were scarcely more than isolated zoological facts, until their relationship to the ])rocesses of fermentation anil i)utrefaction came to be perceived. All this may be perfectly admissible, aud yet this very unexpected outcome of isolated experiences should cause us both to have a profound respect for the potentiality of new facts, as well as to manifest our recognition of their possible value in the future, by faithfully recording them, so that, by-and-bye, we may have them at hand to fit into the theory which may hereafter be found to embody them. Then will they become an integral part of the body corporate of science, with its infinite powers of extension and adaptation to new facts and new conditions. It is lamentable to think how great a loss science must have sustained in the past, by reason of waste of opportunities of recording simple every-day facts. AVe live now in an age of acute observation and systematic record, which bears constant fruit in the bringing to light of vaiious symptoms and diseases too numerous to mention, of which formerly we had no knowledge ; but, except perhaps in the case of some which doubtless are the evolved products of new and modern conditions, these must have exi.sted for ages under our eyes. Some are so obvious and consjucuous that they must have been noticed by men whose work testifies that they were not lacking in acuteness and powers of observation ; but yet, from the absence of any record in the past, we now labour under the dis- advantage of having to approach them, fortified with the few facts of to- day, instead of with tlie accumulated experience of years ; and we may depend upon it that, even now, owing to a simple want of observation and attention, and to an absence of a sufficiently systematic record of passing signs, we avo daily committing the same sins of omission which we lay at the door of our i)redecessors. It is an easy thing glibly to admit the close connection of medical with biological science, and the fact that year by year we lay increasing insistance on the biological part of the medical curriculum, is evidence that this connection is well recognised ; but it is not so easy to define within the limits proper to this address, either the nature or extent of the influence of biological theories upon that which is still so largely and essentially a practical art. Such an attempt, however, I have rashly undertaken to make. If we are to forecast the future, we must realize the ])ast, and the appreciation of what science has ah-eady done, and is now doing, for surgery is a necessary antecedent to the understanding of what its future lines of progress will be. As the most striking example of the profound influence exerted by biological methods and reasoning on surgery with the hajipiest results, the mind turns naturally to those brilliant chemico-biological conceptions of the origin and causes of fermentation and putrefaction, that occupy so 202 IXTERCOLOXIAL MEDICAL COXGRESS OF AUSTRALASIA. much of our thoughts at the present time. There is a ])recisiou in their methods and a brilliancy in their results that speak for themselves, and constitute the best apology for the prominence which, with one accord, we extend to them. If these stood alone, they would be a standing monument to the labours of the biologist, and leave the surgeon for ever in his debt, permeating as they do the whole range of that chief part of the surgeon's work — wounds and their consequences, operations and their i-esults ; nay more, profoundly influencing, and even revolutionizing, all our past ideas of the aetiology of morbid processes. The name of Lister is revei'ed wherever the civilized surgeon dwells ; antiseptics and asepticism loom large in the foreground of the picture of modern surgery ; and yet, while we welcome the benefits, we must admit that, envelo]ied as it is in clouds of uncertainty and even misconception, the theory is far removed from finality. Hitherto, attention has been chiefly devoted to the magnification of the role of aerial germs, and the Listerian method has been chiefly devoted to their exclusion or destruc- tion. A prodigious ingenuity in the multiplication of germicides, and an endless search after perfection in this direction, has probably tended to divert attention from matters of more vital and deeper import ; and, in fact, the experience of many surgeons has shown that successful practice is possible without the exclusion of exti'insic germs. One dis- tinguished member of our ])rofession has observed, or almost boasted, and his practice is largely imitated, that he is in tlie habit of flushing the abdomen after section " with water containing spores and germs of thirty different kinds of beasts," and that his results are as good as those of the strictest disciple of Lister. This is of course the language of hyperbole, liut still it is abundantly clear, that aerial germs are not the be-all and end-all of wound pathology. The role of the living tissues themselves is the one great unknown quantity. Why is it that some wounds are obnoxious to putrefactive changes, or to the aljsorption of harmful products, while others are less so, or escajje unscathed in atmospheres and fluids that literally reek and swarm with germs 1 What subtle property of blood or tissues enables the fleld-mouse to resist the septict^mia which is so fatal to the house-mouse, or the white-cocooned silkworm the disease that devastates the yellow ; or what constitutional peculiaricy shelters the Cochin-China fowl from chicken cholera, or the Algerine sheej^ from anthrax 1 Why wei-e the black pigs mentioned by Mr. Darwin unaffected by blood-root, which poisoned their white fellows, or only the white pigs j)oisoned by buck-wheat 1 Or, even amongst the race of man, what is the essence of these numerous racial peculiarities which here confers immunity, and there a special predisposition to certain diseases. All these and many other similar instances of idiosyncrasies of race and colour in respect of drugs and of diseases have PRESIDENTS ADDRESS — SECTIOX OF SUKCiKKV. 203 l)ocn recently set fortli in an adniiraMe address by Dr. T. Clifford Alll)utt, and it is impossible not to see in this new science of comparative nosology, the beginnings of investigations wliicli are bound to lead us to facts of the highest importance, both in the science and practice of our calling. In short, what is the value of the mysterious and unknown factor that has been termed "tissue resistance?" To say that this is a cpu>stion which will be soon, if ever, accurately and fully answered, is to admit tliat by somewhat of a by-path we shall reach that ultimate goal of physiology — the realization of the essence of organic life, and he would indeed be ])resumptuous who would assume that this knowledge is in store for us. This is not the place to discuss such a question, but it is at least stiimilating to the mind to be always keeping such a definite and crucial issue before it, and whatever failure there may be, and perhaps must ever be, to reach the comprehension of the great ultimate laws of life, it must surely be that facts of the highest practical value will be unearthed by him who will dig deejily into this scarcely opened mine of ]>hysiological action. In such a connection, I cannot refrain from calling your attention to the very remarkable observations of Metschnikoff, which threw quite a new light u}>on the whole question of the capacity of tissues to resist the invasion and progress of morbid processes. Many of tiie results obtained by this observer have been confirmed by that accom[>lished observer, Mr. Sutton, who gives the following graphic account of events as read by the light of their experiments : — " The story of inflammation may be likened to a battle. The leucoctyes aie the defending army, their roads and lines of communications, the blood-vessels. Every composite organism maintains a certain propor- tion of leucocytes, as representing its standing army. When the body is invaded by bacilli, bacteria, micrococci, chemicol or other irritants, information of the aggression is telegraplied by means of the vaso-motor nerves, and leucocytes rush to the attack; reinforcements and recruits arc (juickly formed to increase the standing army, sometimes twenty, thirty, or forty times the normal standard. In the conflict, cells die and often are eaten by their companions ; frequently the slaughter is so great that the tissue becomes burdened by the dead bodies of the soldiers in the form of pus, the activity of the cell being testified by the fact that its protoplasm often contains bacilli, itc, in various stages of destruction. These dead cells, like the corpses of soldiers who fall in battle, later become hurtful to the organism which they in their lifetime were anxious to protect from harm, for they are fei-tile sources of septicaemia and I'ytemia — the pestilence and s^courge so much dreaded by operative surgeons. The analogy may seem to many a little romantic, but it apj)ears to me to be warranted by the facts." 204 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. We further learn from the I'esearches of Metschnikoff, that when the ■white corpuscles first come in contact with bacilli in a virulent form, they are unable to touch them, but if they have been educated, so to speak, by having first had presented to them the attenuated form, they have afterwards no ditficulty in gra()pling with the more malignant. If this be so, we get a long step nearer to a rational explanation of the modus operandi of vaccination, and of protective inoculation generally. Nor can we shut our eyes to the importance of the recent researches on those alkaloidal products of ])utrefaction, or of normal physiological tissue activity, called by the somewhat barbarous name of ptomaines and leucomaines, for the knowledge of which, and especially for the distinc- tion between the two kinds, we are largely indebted to Gautier. Intensely poisonous, continually being formed even in the healthy body, demanding constant excretion, the body seems to exist in constant peril from the foes of its own household, and it is possible that the retention of these products may be found to account for many hitherto unexplained phenomena. Already a fundamental distinction seems to have come out between the hyperthermia which attends poisoning by the physiological extractives and the hypothermia which is a feature of poisoning by the putrefactive alkaloids. The pole-star of the eftbrts both of the biologist and surgeon is, the hope of a better understanding of the nature of these living actions ; towards tJie much wished for goal we are travelling, the one along the broad road of normal processes, the other along the more crooked jiath of abnormality and disease. To the biologist belongs the credit of having discerned that his road lay through the cellular theory; to the surgeon a timely discrimination in having quickly |)erceived that the track taken by his fellow-traveller — the biologist — was in the right direction. Thus, the establishment of the cell theory was quickly followed by a cellular pathology, and henceforth, the two paths slowly converge, and if ever they meet and coalesce, it will be in the solution of the ultimate jjroblems of organic life ; but it may also be that these two paths represent the familiar mathematical concejition of two lines which are continually nearing one another, but which, even if prolonged to infinity, will never meet. I think that we surgeons may often scarcely realise the important bearing which this cellular theory and pathology bears to the science of surgery, inasmuch as its establishment signalizes that holy alliance between })hysiology and pathology, to whose fruitful union we owe the all-important generalisation, that morbid pi-ocesses are but perturbations of those of health ; and that to couii)rehend therefore the abnormal, we must first understand the j;iormal, not forgetting that tlie converse may php:side\t'.s address — section' of suRfiEuv. 205 ])e true, in that the abnonnal may sonietiine.s shed an uuexjiccted light upon the norniah Wliat thoughtful and conscientious surgeon is there who is not deeply sensible of the opjtrobrium which rests upon his calling, as well as of his own impotence, for his incapacity to arrest the ravages of cancer, and of those tumours we call malignant, in acknowledgment of their baneful jirogrcss ; how ignoi'ant are we yet of their real origin ; how unable even to state bald but incontestable facts as to their infectiousness or hereditary descent. True it is, that neither any theories of cells or germs have yet enabled us to answer these questions; nevertheless it is plain that, whether we regard cancer as due to the vagaries of cell growth, or to the running riot, so to sj)eak, of the activities of primordial pi'otoplasni, independently of cell growth, or with whatever theory we approach the ([uestion, it must bo to a better understanding of the normal processes of living tissues that we must look for the explanation of this terrible example of aberration from them. What boasted triumi)h of operative surgery, indeed, could compare with such a knowledge of the caiises of these activities as would enable us to forefend the direful consequences of this, it is to be feared, increasing scourge of humanity ? There are few questions of greater importance to the surgeon than that of inflammation ; kept within bounds, his best and surest ally ; but, running wild riot, his most dreaded enemy. Ignorant of its nature, origin and causes, our treatment of it has hitherto l>een hardly better than a rule of thumb ; and yet, nothing seems more clear tlian that the whole process may be expressed in terms of perturbed nervous action, and heightened tissue metabolism ; the conditions dete)-mining which it is permissible to us to think might possibly be determined, averted, or attacked with scientitic precision. Already, T think, we have made some distinct advances in this direction, and I am confident that the [)liysiological basis on which we are proceeding is at last sound and rational. It is, as we know, often unwise to prophesy, but such a concej)tion as that just stated raises in the mind visions of what may be some important lines of ad\ance for our calling. We surgeons are sometimes in the habit of indulging in not a little self-glorification at what we have done for the assistance of our medical brethren, by the importation of surgical procedures into what, by an artificial distinction, have been considered as medical diseases. Physicians will, I am sure, ungrudg- ingly acknowledge the great assistance they have thus received ; but there is a way in which medicine may reciprocate, and repay with interest its debt to surgery. Its professors and practitioners may make themselves responsilde for more rational and precise methods in pharma- cology and therapeutics. For too long has the whole of our profession, 206 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. physicians as well as surgeons, rested under the stigma of being mere empirical administrators of drugs, or exponents of a haphazard poly- pharmacy. There has been too much truth in the observation of that scorner of physic, who compared nature and disease to two men fighting, and the doctor to a blind man with a club, who strikes in, sometimes hitting the disease, and sometimes hitting nature. But there are signs of great improvement. Already in the case of curare, atropine, muscarine, physostigmine, pilocarpine, strychnine, veratrine, cocaine, and some other drugs, notably those termed antipyretics, we see the dawn of better days for pharmacology and therapeutics. There is a degree of precision in their application, and of accuracy iu the effects produced, that augurs well ; and, in the case of some of these drugs, there is an encouraging approach to knowledge of physiological action of a precise kind that was undreamt of not long ago. As Professor Huxley has stated the case, "there can surely be no ground for doubting that, sooner or later, the pharmacologist will supply the physician with the means of affecting in any desired sense, the functions of any physiological element of the body. It will, in short, become possible to introduce into the economy a molecular mechanism which, like a very cunningly- contrived torpedo, shall find its way to some j/articular group of living elements, and cause an exjjlosiou amongst them, leaving the rest untouched " There is yet another fertile but as yet almost untilled field of research for the surgeon, as well as for the physician, which, if it is to yield its harvest, must be dug with biological tools. What do we know about tliat great factor in disease — hereditary influence, and its laws 1 Almost nothing ; and yet w^e cannot doubt that the laws of evolution, of which heredity is so great a factor, are as ap[)licable to disease as to health. That mysterious influence which stamps the offspring with resemblance to its parent, cannot be sui)posed to be confined only to face and form, or to mind and morals. It must extend to all organs alike. If there is a family heirloom in faculty and feature, there will also be a davmosa ha-reditas in liability to disease ; but saving that in a vague and general way we recognise that there is some sort of liability exist- ing for certain diseases, such as gout, phthisis, malignant tumours and deformities, to be transmitted, we can make very feAv definite statements concerning the extent of such liability, still less can we formulate any quantitative laws which regulate their transmission. Although it is scarcely likely that we shall understand the intricacies of jtathological heredity until wo liave a better understanding of its normal or physiological aspects, there is, notwithstanding, but little doubt that bright and discriminating side-lights, revealing facts and clues of high importance, may b(! thi-own u])on the whole general question of president's address— section of surcery. 207 descent by instances of the transmissiou of defonnities and disease, just as in tliat very difficult and obscui-e suliject of nerve physiology, the experimental method has received niuch elucidation from pathological observations. Now, the whole (juestion of heredity, with its inextricably interwoven factors of anatomical, physiological, psychological, and pathological effects, is of such enormous import, both to the human race in general, and to our own profession in particular, as bearing on the transmission of actual disease, of liability to sj)ecial disease, or whatever exjiression we may adopt to describe something we do not very well understand, that it behoves medical men, who alone as a class are in a position, and who, by their education, are especially fitted for the task, to contribute and accumulate facts which are calculated to throw light upon a subject of such impoi't- ance. This is onl}' one of the many ways in which collective investigation in Australia might be turned to the best account, and might supplement similar labours elsewhere. By methods, singularly ingenious and painstaking, Mr. Galton, whil(3 always begging for co-ojieration from the medical i)rofession, has set us an exam{)le of how this kind of research may be successfully carried out on statistical ])rinci^)les ; and 1 believe this Congress might, with the greatest advantage, set on foot a scheme that would in the end result in the accumulation of a vast amount of well observed and well recorded facts, without which assuredly there will be no recognition of the general laws of which we are in search. Not only are these cpiestions of heredity of immediate importance to us as practitioners, but it is impos sible to forget how great a factor it is in the great law of evolution, })erpetuating and fixing, as it were, the variations of organic life ; and assuredly the time may, and I think will, come when we shall have to ask ourselves whether that mighty force is ever to drive us before it like dead leaves, or whether rather, we have not the knowledge and the ])Ower to direct and regulate its influence for the benefit of our race, as we have already been at some pains to do for the beasts of our fields. To talk now of evolution under any aspect, would lead me far beyond my mark, but there is no doubt that a wholly new and often unexpected light is thrown upon many pathological produ.cts, such as tumours, deformities, and abnonnalities, by reference to their mode of origin from structures that are, so to speak, relics of inferior organisms or of early conditions which, by their survival or re-appearance, stamp us indelibly with the mark of our lowly origin. Labours, such as those of Sir James Paget and Mr. Sutton, have made us fully alive to the alsundant harvest of facts to be gathered from this wide and neglected field of comparative pathology. 208 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. I am well aware, Mr. President and Gentlemen, that the facts which I have been permitted by your forbearance to relate, however interesting and important they may be in themselves, do not, as thus crudely and badly stated, constitute an answer to the inquiry which stands at the head of this address. I have not been desirous of shirking that issue ; but I felt that I should approach it better if the ground were cleared by a sort of preliminary survey of some points which, I hope, ai'e not without a distinct bearing upon the main question. And, being thus now in some Avay fortified, I propose to attack that question to the best of my ability. It has been often said that there is no ideal science exce])t that which is exact, or in other words, which can be submitted to the control of number, weight, and measure, and the statement is })erha})S correct, but it is not true that there is no science except that which is exact. If this were so, the domain of science would be narrowed down to mtithematics and portions of physics and chemistry ; nay more, we should have to despair of bringing much knowledge, that we now rightly count as scientific, within such a definition. For instance, with the most sanguine expectations, it is to say the least of it doubtful whether the primary and fundamental facts of biology, and of the numerous branches of knowledge which proceed from that gi-eat parent trunk, can ever be satisfactorily submitted to such tests. But short of this, we may have science both in substance and in method. As in the case of INI. Jourdain's prose, it sometimes comes as a sur})rise to people who have looked upon scientific knowledge as diff'ering toto ccelo from the ordinary knowledge of every-day life, to learn that there is no such difference, and that such knowledge as they themselves ]>ossess, which is based upon accurate observation and logical deduction, is truly and genuinely scientific. Science, in fact, is not a mode of knowledge sui generis and it employs no methods wliich are exclusively its own. Its difl'erence from the ordinary knowledge of every-day life is one of degree only, in respect of the greater extent and complexity of its range, and in the exactitude of its methods and deductions. Just as in nature, niliil fit per scdtum, there is no sudden transition from one kind of knowledge to the other, bat the higher and more de\'eloped form has grown out of the other by a gradual and rational process of evolution, which is ever con- tinuing and ever widening in its range. Still, if it be permissible to mark off roughly epochs in this gradual process, one may recognise three sta"X's in the growth of a science. In th(> first place, there is the collection of a numl)er of accurately observed, well attested and carefully recoxxled facts, obtained by experiment or otherwise. Then comes the tlie detection of tlu; genuine and constant element pervading the facts, in other words, the determination of tlic^ law which covers and includes PKKSIDKXTS ADDHKSS — SECTION" OF SUllOKliV. 209 them. Lastly, there is the verifieiitiou of the la\v, by its ai^plicatiou to new facts. To these three stages we may in the case of tlie iileally-exact sciences add a fourth, that of y dragging, as I have sometimes .seen done, a semi-solid growth through an aperture far too small to admit of its easy extraction. When the parietal i)eritoneum is found to be adherent to the parts beneath, the usual plan of prolonging the incision upwards, until a pai-t is reached where no such adhesion exists, is the best. A long incision is infinitely less disadvantageous than the dehiy and injury caused by '218 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. stripping tlie parietal peritoneiun from tlie abdominal wall, a mistake ■which I have seen committed on more than one occasion, when the above mentioned rule lias been neglected. Absolute luemosfasis. — The importance of checking bleeding, during all stages of the operation, cannot be too strongly urged upon the young operator. The surgeon of large experience in abdominal operations may, perhaps, afford to neglect absolute lu^emostasis until just before opening the peritoneum, but the inexperienced one should never do so. The flow of blood renders the different structures difficult of recognition, thereby prolonging the operation, and adding to the risk. Especially is it im- portant to stop all bleeding in the case of patients in whom the layers of the abdominal wall are matted together, owing to a previous laparotomy, and in whom, also, adhesion of the intestines to the parietal peritoneum is likely to be found. It is exactly in this last condition that free haemorrhage is met with. 1 am firmly convinced that the slipping of a ligature has, in many cases, arisen from the imjjerfect manner in which it has been tied by the slippery blood-stained hands of the operator. Here, in passing, I should like to emphasise the value which I attach to irrigation, which keeps the fingers of the operator clean, and washes away all traces of blood. It is reasonable to suppose, that the saturation of the ligature with blood increases the risk of septic infection. We all regard it as of the highest importance to sponge or wash away all traces of blood from the peritoneal cavity, and yet perhaps we are indifferent to the retention of some of that fluid in the meshes of our ligature. Inflltration with blood of the tissues of the abdominal wall, contiguous to the line of incision, also increases the risk of septic infection, as well as the formation of abscess in the parietes. To assist in ol)viating this infiltration, and at the same time to prevent disturbance of the planes of tissue and retraction of the cut edge of the ])eritoneum, it is, I think, a good plan to pass a ligature through either side directly the peritoneum is opened. These ligatures also enable the assistant to hold the edges of the wound apart during the further progress of the operation. Fiat sponr/es. — The peritoneal sac being opened, warm flat sponges should be brought into as extensive use as possible. For isolating the part to be operatetl u[)on; for protecting the bowels and other viscera from un- necessary handling and exposure to the carbolic spray, if that be em- ployed ; for sopping u[) blood and other fluids, and for shutting out the large absorbing anil s:ensitive surface of the peritoneum, and thus obviating the risk of carbolic acid poisoning and shock — for all these pur[)oses, flat and warm sponges are most useful. I am confident, from observation, that they are not made as much use of as they shoidd be. By their use, also, is obviated that prolonged final sponging of the peritoneal cavity which we sometimes witness. Clamping hleedinr/ vessels and adhesiovs.— It is scarcely necessary to urge the propriety of not waiting to tie vessels or adhesions, but to clamp them until the operation is completed. Many vessels will then be found not to requiie the ligature, the compression of the forceps having been sufficient permanently to stop tlie bleeding. I make mention of this practice, because of its bearing on the duration of the oi)eration — an important element in the immediate mortality of many ca.ses of lai)arotomy. LAPAHOTOMV. 219 W(ii the i)atient for several days under the influence of o[)ium. Lawson Tait in England, and Dr. T. M. Baldy in America, have opposed this practice, and maintained the advantage of administering saline aperients afcer the second or third day, unless the bowels have been moved spontaneously. They regard this treatment as specific against the tyni|)anites, vomiting, and jiain, which we so fre- quently meet with a few days after laparotomy has been performed. Tait says — "I always find tliat as soon as a motion has been passed, the symptoms of distension, vomiting, elevated temperature, and quick pulse rapidly disappear." Dr. Baldy .says — " Logically, salines are infinitely better than opium. We are taught tliat opium puts the bowels * in splints,' and in this manner keeps the peritoneal surfaces from rubbing together and increasing the inflammation. But the bowels are already in splints, as it were, and anyone trying to make them move will be quickly convinced of this fact — therefore, for this purpose, opium is superfluous. The drug i-elievcs the pain, it is true, but oftentimes it does not even do this, except in enormous doses. Belief of jiain is practically all that opium can do for good in peritonitis. It, however, does a world of harm — it helps to keep the bowels in splints, and so favours the forujation of those great masses of adherent intestines which we And so often the cause of subse(]uent intestinal ob.struction; also the LAPAHOTOMV. 221 formation of numerous l)an(ls of organised lymph, wliicli as often brin<^ a patient to one in after years. Still worse, it closes all tlie avenues of escape for the poisonous products of intlannnation formed in that great lymph sac, and in this manner, sup])lies material the best possible for keeping up and spreading the intiamniation, much more surely than the rulAiing together of the parietal and visceral peritoneum will. With salines, on tlie contrary, the bowels are kept in active peristaltic motion, and this very motion tends to prevent the formation of adhesions and I'linds — they literally drain the peritoneal cavity of all products of inflammation. This is not merely theoretical, but has been repeatedly observed." Dr. Cxill Wylie advocates enemata for the relief of tym- panites, vomiting, and pain ; and if these fail, a quick purgative. This question of the administration of salines and ai)erients bears upon that which I discussed a few minutes since, namely, the production of artificial ascites. I opine, that the peiistaltic action of the bowels serves the same purpose as the artificial dropsy- — jn'eventing adhesion — in the one case by causing the intestines to alter continually their relative positions; in the other, by keeping them asunder with a layer of fluid. No doubt salines have also the effect of promoting absorption of fluid from the peritoneal cavity, and of carrying off septic nnitters. In my own practice, the custom has been to administer, per rectum, only a moderate dose of opium immediately after the o})eration, to relieve pain and shock, and to give no more unless the pain should become continuous and severe, the bowels being relieved \\h\i enemata. When to Operate. In all injuries and diseases of the abdominal cavity where operation is entertained, there are ahvays special circumstances which influence our decision as to the [iroper time to operate ; but there are also some general considerations common to all forms of disease and injury of that region, wliich may now be mentioned. I may say, by way of ])reface, that the introduction of the antiseptic method has modified, in a remarkable degree, the views formerly held as to the best time to oi)erate. And when I sjjcak of the antiseptic method, I mean every- thing calculated to secui'e absolute cleanliness, and therefore, the prevention of access of pathogenic germs into the wound, as well as the employment of germicides. It was reasonable, that when the ojieration of laparotomy involved great risk to life, that it should be delayed as long as possible, and oidy performed as a last resort. When that risk became greatly reduced, postponement to a late date in the course of the disease was no longer propei-. I venture, however, to say — though in saying it, I am awai'e that I shall run counter to current opinion — that in the case of ovarian and other tumours, there is still some advantage in waiting for a time until the peritoneum has become accustomed to the i)resence of the growth. There is, I feel convinced, some value in what may be called the " apprenticeship of suffering." Previous suffering, pro\'ided it lias not been excessively severe or prolonged, does, in my oi)inion, in some way prepare the nervous system for a severe operation. In fat subjects, delay also is advantageous, for the difficulty of the operation in them is increased by extreme deposit of adipose tissue in the abdominal wall, and in the cavity of the '22'2 IXTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA, belly. Ill them also, the risk of septic absorption is increased, owing to the unavoidable disturbance of the fat cells, and the escape of free fat into the abdominal cavity. In the following conditions, however, laparotomy should be performed without delay : — (1) In acute general peritonitis arising from injury, or in the course of disease. (2) In any case in which blood, pus, urine, or any foreign matter lias escaped into the peritoneal cavity. (3) Where urgent pressure-symptoms, especially those affecting the lieai't, lungs, or kidneys, arise. («) Dr. Bedford Fenwick has well pointed out, that the most common cause of sudden death after laparotomy for ovarian, renal, or cystic disease of the abdomen, is fatty degeneration of the cardiac muscle, with thinning of the walls of the right ventricle, and dilatation of its cavity— effects directly due to the powerful upward pressure of the increasing cyst, ])ressing upon the afferent and efferent vessels of the heart and u])on the lungs ; interfering in the one case with its blood-supply, and in the other, bringing about deficient oxygenation. (b) Rapidly-developing bronchitic irritation, or dyspnoea, due to pressure upon the lungs and pleura, or due to hydrothorax, though the last named may, of course, be temporarily relieved l)y paracentesis of the pleura. The grave bronchitic trouble, with jn-ofuse purulent expectoration, which sometimes arises from the ]>ressure of the rapidly-enlarging ovarian cyst, was well illustrated in my first case of ovariotomy, performed eighteen years ago. It was so severe, as to cause considera1)le anxiety as to the condition of the lung substance, and as to the ])ropriety of operating at all. Twenty-four hours after the operation, the cough and expectoration had entirely dis- appeared. (c) Eapidly -increasing albuminuria, from pressure on the renal vessels, is a manifestly urgent cause for immediate operation ; as also is direct pressure on the ureters, producing symptoms of suppression of urine. (4) Where there is great and )-apidly-increasing emaciation. (.5) Finally, where the patient is of advanced age, if operation is to be done at all, it should be done without delay. Cardiac degeneration is much more likely to ensue in a patient suffering from ovarian tumour of large size when over forty years of age, than when younger. The general contra-indications to laparotomy are those which pertain to the performance of all major oj^erations, namely, extreme collapse from injury, injuries to other parts which must necessarily prove fatal, very advanced disease of the kidneys, heart, or lungs. Pregnancy, although adding somewhat to the risks of laparotomy, is by no means a contra-indication. Many ovarian tumours have been removed during pregnancy, which has, nevertheless, gone on to full term ; and I have myself seen the abdomen opened in a case of suspected extra-uterine foetation, when the condition i)roved to be normal, and no ill result followed. Hei'editary tendency to insanity should caiTy some weight, as a conti'a-indication to ovariotomy, in a case where the LAPAROTOMY. 223 advantages and disadvantages of tlie operation are otherwise ))retty equally balanced. Cases of madness following tlu; operation liave been recorded by Barwell, Keith, Thornton, Bryant, Alban Doran, and myself. It is trne that all recovered their sanity, thongh in some, as in the case recorded by me, not for many months after the operation. Laparotomy has been i)erformed for gastrotomy, gastrostomy, pylorectomy, ruptured intestine, punctured and incised wounds of the intestine, gnnsliot wounds of intestines, rupture of liver, rupture of spleen, rupture of large blood-vessels, rupture of urinary or gall bladder, rupture of uterus, ruptured tubal pregnancy, perforation from ty])hoid ulcer, abscess, intussusception, acute intestinal obstruction, chronic intestinal obstruction, tuberculous pei'itonitis, purulent peritonitis, liydatids, hydro-, hfemo- and pyo-salpynx, Ciesarian section and Porro's operation, removal of spleen, nephrotomy and nephrectomy, chole- cystotomy, oophorectomy and removal of tlie appendages, hysterectomy, enucleation of fibroids and cysts, ovarian and parovaidan cysts, cysts arising from dilatation of a patent urachus, extra-peritoneal cysts of unknown origin, cysts of the mesentery and omental cysts, lipoma of omentum, aneurism of the abdominal aorta and its branches, and finally, for exploratory purposes. Gastrotomy. Gastrotomy, for the I'emoval of foreign bodies from the stomach, has now been performed several times with success — the incision in the wall of the viscus being closed with Lembert's, or the continuous suture. With far less success, as might be expected, but still with some encoui'agement, it has been done with a view to dilatation of the orifices in cases of cicatricial structure. Pi'ofessor Loreta, of Bologna, originally proposed and ])erformed the operation with this object, and a few others have followed his example. Gastrostomy. Gastrostomy has now been ])erformed in a large number of cases for obstruction of the cardiac orifice of the stomach, or of the cesophagus — malignant or cicatricial. The mortality in the malignant cases has been high, but in the cicatricial as low- as 29 ])er cent. If done in the early stages of obstruction, the mortality is much less than if deferred to the later. A painful death by starvation, at any rate, is obviated. The fatal issue in the malignant cases has been due to the spreadin<'- of the disease which rendered the oj)eration necessary. Several methods have been adopted of fixing the stomach in the abdominal wound. Tliis may be done by double suturing, after Howse, by hare-lip, or acu-pressure or safety pins, or by pressure forceps, the blades of which are covered with indiarubber, and the handles stitched to the abdominal vv'all. By the last mentioned method we avc^id puncture of the walls of the stomach, but I think, from observation of two cases in w])ich the forceps were used, that close contact of the gastric and parietal peritoneum is not so perfectly secured as by sutures or hare-lip jiins. Whatever plan we adopt, we must be careful not to open the stomacli befoi'e pretty firm adhesions have been formed. This mistake I saw 224 IXTERCOLONIAL MKDICAL COXGRKSS OF AUSTRALASIA. committed on two occasions, hotli cases jn-oving fatal within a few days. Tiie exhansted condition in which these patients usually are before operation, and their low vitality, render the process of inflammatory adhesion slower than it would be in a healtliy individual. This same state of exhaustion also makes the surgeon anxious to o[)en the stomach at the earliest possible moment, in order tliat stomach feeding may be commenced. To meet this difticulty, I would suggest the advisaliility of injecting milk or other liquid nourishment into the stomach by means of an aspirating syringe. The minute puncture made with the needle is at once closed by the bulging into it of the mucous coat of the organ, and all leakage is prevented. This injection may be commenced immediately on the conclu.sion of the tirst stage of the operation of gastrotomy, and repeated every few hours as may be thought necessary, until firm adhesions have taken place. If rectal feeding be combined with the plan of injection just described, the patient would be well sustained until such time as it was thought to be [)erfectly safe to open the stomach. The adoption of tiiis plan will also render unnecessary that which English surgeons at any rate regard as very undesirable, namely, immediate opening of the stomach. PVLORECTOIIY. Pylorectomy is only practicable when the [)yloric end of the stomach is quite movable, and the lymphatic glands in the neighbourhood are iniaffected by the disease. When these contra-indications exist, duodenal or jejunal gastrostomy should be performed. Indeed, there is a growing tendency to sulistitute one or other of these operations for pylorectomy, in all cases of malignant disease of the pyloriis. COXTUSION AND RuPTURE OF THE IXTESTIXES. The difficulty of diagnosing simjile contusion, from rupture, is great. The symptoms of shock are undistinguishable from those of collapse from loss of blood. In simple contusion, it is manifest that delay is desirable, as the patient may recover without any operation, if the injury be not so severe as to lead to subsequent sloughing of the bowel. In rupture, delay will probably be fatal. The history of the injury may sometimes give us a clue. Should the abdomen become universally tympanitic, we know tliat gas has escaped into the peritoneal cavity, and that rupture has taken place. Emphy- sema of the subcutaneous cellular tissue also, from escape of gas into that structure, at a part where the bowel is uncovered by peritoneum, will give us the same information. As far as I can ascertain, not a single case of recovery, after lai)arotoniy for ruptured intestine, has taken place. There are prol)ably two reasons for this, exclusive of shock — First, that in consequence of the difficulty of making a correct diagnosis, the operation has been too long delayed ; and secondly, that in con- sequence of bruising of the bowel beyond the actual site of rupture, necrosis is apt to occur, with extravasation of the intestinal contents. Pi-obably the best practice in all cases of rupture, except those situated very high up in the alimentary tract, is to estal)lish an artificial anus, thus avoiding the risks of extravasation, and affording the bruised bowel l>elow the anus absolute rest, and a better chance of escaping LAPAROTOMY. 225 necrosis. Enteroytouiy also occupies so inucli less time than suturino', or i-esection, that it obviates the risk of a prolonged operation- — a most important matter in the cases we are considering, where shock is so cons])icaous a feature. I cannot 1)Ut think that putting aside shock, the tendency to sul)- sequent gangrene of the gut, in the cases in which the l)Owel has been sutured and returned, explains the remarkal)le difference in the mortality of laparotomy for this lesion, and that for stabs and pimctured wounds of the intestine, where the recoveries are about 66 per cent. Gun-shot Wounds of the Abdomen Involving the Viscera. Much difference of opinion has been expressed as to the prourietv of probing gun-shot wounds of the abdomen which may possibly invoh e the underlying viscera. When done carefully, and l)y an experienced hand, I can see no objection to such a proceeding. A'aluable informa- tion as to the direction the missile has taken thi-ough the abdominal cavity may be acquired — for that direction will u.snally be the same as that of the tiack through the abdominal parietes. Further, I see no objection to laying ojjeu the track if it be not very extensive, and so ascertaining with certaint}^ whether the peritoneum has been punctured, and also obtaining some definite information as to the })robable track of the bullet through the ])eritoneal cavity. When the direction of the missile renders it probable that one of the fixed viscera (and in this class I include the large intestine) has been injured, incision directly over the site of the o)'gan will ])robably be the best. On the other hand, when that direction would indicate that the movable viscera, and especially the jejunum and ileum, have been involved, then I think the median incision should be chosen. If it be impossible to ascertain the probable direction, then also, the linea alba should be selected. Perforating ulcers of the bowel, when due to foreign bodies, gall stones, or Viurns of the skin, demand immediate lapai'otomy, if the diagnosis can be made. In typhoid and tuberculous ulcers we have, in most cases, to deal with patients already greatly exhausted by the disease, and with a large tract of intestine, if not actualh^ involved in ulceration, yet in a condition which renders healing, after a plastic operation, most unlikely to occur. Under such circumstances success cannot be expected. When ])erforation occurs during convalescence, and especially when it occurs in those cases of mild typhoid, which my old teacher, Dr. W. H. Walshe, used to call "peripatetic," then laj^arotomy will afford the patient a fair chance of recovery. In perforation of the appendix vermiformis, we are beset with the difficulty of deciding whether we have to deal with actual perforation of the appendix, or with a typhlitis. Could we, with certainty, differentiate these conditions, our proper course of action would be clearly defined. Early operation in cases of perforation is our duty, whereas the vast majority of the cases of typhlitis will get well under judicious medical treatment alone. By judicious, i mean the absolute avoidance of all purgatives, witli rest, and liquid nourishment in very small quantity. Late operation may be ne(-ded in some cases of perityphlitis, owing to suppuration in the cellular tissue of the iliac fossa. When this does occur, the retro-peritoneal ojjeration should be performed. In all other Q 226 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. cases, when operation is required, incision directly upwards from about the middle of Poupart's ligament will usually afford the readiest access to the aifected parts. Since writing the above, I have read the report of a discussion intro- duced by Dr. Bull, of New York, at the Medical Society of London, on the surgical aspects of typhlitis and perityphlitis. Dr. Bull opened the abscess extra-peritoneally in ten cases, and they all recovered. He advocates the use of the exploratory needle to determine the presence of pus. Dr. Bull, Mr. F. Treves (of London), and Dr. Weir (of New York) expressed the opinion, that in all cases in which abscess forms, there is perforation of the appendix. Dr. Bull concluded his paper with the aphorism, that the risk of operation was less than the risk of waiting. Intussusception. It is, I think, clear that the great fatality, which has until within the last twelve months followed the operation of laparotomy for intussusception, has been due to the fact that it has been put off until a late stage of the disease — that, in fact, it has been looked upon as a proceeding to be adopted only as a last i-esource. I entirely agree with Mr. A. E. Barker, of University College Hospital, London, who contends that, as in an ordinary case of hernia we are always prepared to operate upon the failure of the taxis, so in intussusception, when failure has attended the efforts at reduction by inflation, injection, and inversion of the body, we should be prepared at once to do laparotomy. The longer we wait, the more surely will the case become one of " strangulation," instead of being, what it is in the early stage, one of "incarceration." Strangulation existing, reduction of the invaginated portion of gut will be probably im])0ssible. To trust to the possible recovery of the patient by the perilous process of sphacelation, and casting oft' of the strangulated intestine, is unjustifiable. The recent remarkable diminution of mortality, which has attended abdominal section for intussusception since this rule has been followed, gives strong support to the justness of Mr. Barker's view. Chronic Intestinal Obstruction. Division of adhesions or bands, enterostomy and resection of the intestine, are the methods which have been ordinarily adopted for the relief of chronic intestinal obstruction. Mr. Lawford Knaggs has proposed a fourth method, namely, union of the gut above the obstruc- tion with some portion of the tract below it, the part of the bowel involved in the obstruction being left in situ. When adhesions are extensive, and it is found impossible to separate them, or where the cause of the obstruction cannot be discovered, enterostomy will probably be the best ])rocedure, Mr. Lawford Knaggs' method, just mentioned, being followed if the obstruction be high up in the small intestines, so as to obviate the escape externally of the contents of the upper part of the tract, and the rapid wasting and death by inanition, which such loss invariably brings about. The exhausted condition of the jiatient also may bo so great that a rapid operation is necessary, and then enterostomy will be the best method. r.APAKoroMY. 227 Mr. Lawsoii Tait deprecates any pi'olongecl search being made for tlie cause of tlie ol)Struetion, and ))ractises enterostomy in a lar"e number of cases of obstruction. Whatever may be the e.x;planatii)n of the way in which enterostomy cures, practically it is found that evacuation of the intestinal contents, and the resulting relief of distension, do, in many cases, remove the obstruction, and it becomes possible to close the fistula subsequently without any riiturn of the symptoms, the lumen of the l)owol being apparently (|uite restored. Absckss of Liver. In abscess of the liver, incision through the i-ight linea semilunaris, stitching the capsule of the liver to the wound in the parietal peritoneum, or if there be no need to hurry, stuffing the wound with carbolised or sublimate gauze to excite adhesion, opening and drainage, constitute the plan ordinarily and successfully adopted. I siiould not have. alluded to it, but to point out that sometimes, owing to the position of the abscess, it is found difficult to secure free drainage. When this is likely to be the case, the suggestion of Kartulis should be borne in mind, namely, that of re-secting portions of one or more ribs. The manifest disad\antage attending this ])lan is, that the diaphragm will frequently have to be cut through, and if there be no adhesions, there is danger of the pus entering the pleural sac. Tn one case of hydatid cyst of the liver which came under my oljservation, and which was treated in this way, infection of the ])leural sac actually occurred. Stitching together the diaphragmatic and costal pleura^, if possible, before opening the abscess or hydatid cyst, and thus shutting oti' the pleural cavity, would probaljly obviate this danger. Tumours of the Kidney. The battle of the lumbar and abdominal methods, for the removal of kidney tumours, is still unsettled. Mi'. Knowsley Thornton strongly advocates the abdominal method ; Mr. Morris is a warm supporter of the lumbar. In course of time when we become capable of more precise diagnosis, we shall probaljly tind that tumours of a certain size, nature, and position, will be best removed by the one method ; whilst tumours, presenting the opposite characters, will l)e best dealt with l>y the other method. Tlie lumbar method, avoiding as it does all interference with the peri- toneal cavity and its attendant risks, naturally disposes us to select it if at all practicaljle, especially if our experience of abdominal surgery has not been large. On the other hand, it has special I'isks of its own, and the most serious of these, and a necessarily fatal error is, that of removing the only kidney which the patient possesses, or the only one which has functional activity. The abdominal method enables us to examine the opposite kidney to that upon which we ju'opose to operate, and thus to avoid a most lamentable mistake. Recenth', in witnessing the post-mortem examination of the body of a medical man, whose case I had had sevei-al opportiinities of observing from his boyhood, the risk of which I am now siteaking was strikingly demonstrated. For some years he had had a pyelitic swelling on the right side, of calculous origin, no tumour having been noticed on the left side. We found the left kidney completely saccular, all renal secreting tissue having dis- Q 2 228 INTKUCOLONIAL MEDICAL COXORESS OF AUSTHALASIA. appeared. The tumour on the right side consisted of the dilated pelvis of the kidney, with saccuhir dilatation of a considerable part of the organ itself, whicli however, still had a large portion of its excretory structure iinattected — manifestly, this kidney was the only one that had been doing any work for some years. Had removal been proposed, and the lumbar method selected, the surgeon would certainly have operated on the right kidney, and thereby cut short the patient's life. Still more recently, another illustration of the advantage of the abdominal method came under my observation. An hydatid tumour of the right kidney was diagnosed, and although its most prominent and accessible part was in front, still, as it could be pushed well back into the loin, the surgeon ])roceeded to opei'ate from the lumbal' i-egion. The ascending colon was found to be so closely and firmly attached to the tumour, that it was impossible to incise the latter without risk of injuring the bowel. A laparotomy at the right semi-lunar line was then made, and at once the surgeon came upon the cyst wall, which he stitched to the parietal wound, opened, evacuated the daughter cysts, and introduced a drainage tube. It is true that, during the progress of the lumbar operation, it became doubtful whether the tumour was connected with the kidney at all ; liut the possibility of mistake as to the exact seat of the growth is another argument for the abdominal method. Where there is a hydro or P3'0- ne[>hrosis bulging into the loin, no doubt the best plan is to incise and drain from that site. Subsequently, should removal be required, and the tumour have become shrunken, lumbar ne])hrectomy may be practised, if there is reasonable probability that the opposite kidney is so\ind. Should there be any doubt aljout this, or the tumour be still of large size, abdominal section should be performed, both kidneys examined, and either the trans-jjeritoneal of Terrier, or the retro-peritoneal method of removal, be adopted. The cut end of the ureter may either be attached to the parietal wound, or preferably in some cases brought out through a puncture in the loin, and stitched to the skin in that situation. If after oi)ening the abdomen in any case, it be found that removal from the loin offers the greatest advantages, a hand in the abdominal cavity, steadying the kidney, will much facilitate the proceeding. Myoma of the Uteuus. In the treatment of fibroids of the uterus, five jilans are open to us, exclusive of the electrolytic. Each of these will be appropriate in certain cases: — 1st, treatment by drugs ; 2nd, removal of the appendages; 3rd, enucleation ; 4th, hysterectomy ; 5th, ligature of the pedicle, and return of the stump, as in ovariotomy. The last mentioned will only be api)licable in the case of pedunculated tumours, and then but rarely. The medical treatment cannot be considered here, but I may say in passing, what perliaps some surgeons are apt to forget, that much may often be done by dieting, especial!}' al)stention froni animal food and alcohol, and also by the aid of drugs. In a large number of cases, no other ti'eatment is recpiired. Removal of the ajipendages has been fre- (juently practised for intra-mural bleeding or [)ainful myomata. It is often found to be impossible of execution, owing to the large size of the tumor, and the imi)Ossibility of bringing the ovaries to the surface. In cases also in which the fibroid is found to be undergoing cystic degenera- tion, removal of the appendages has proved useless. When practicable, I LAPAKOTOMY. 220 tliis ]'>roceetling sliould lio practised in ])reference to enucleation or liysterectoniy, as involving less risk to life. It is of importance to ap])ly the ligatures as close as possible to the uterine wall, and thus to diminish the blood su)>ply as far as practicable. I have witnessed two cases of intra-peritoneal enucleation of fibroids of the uterus, and the proceeding was in both cases a formidable one. In one, as many as fifty pairs of Ka4)erle's forceps were in use at the same time, comjiressing the mouths of bleeding vessels. Only when the fibroid is extra-mural, and eitlior non-pedunculated, or with a very broad and short pedicle, is enucleation likely to be attem])ted; and the large raw and readily absorbing sui-face which is left, constitutes a risk wliich is ])robably greater, in most cases, than that incurred in })eiforming hysterectomy. Provision for very complete drainage is also necessar}'. The oidy case illustrating the fifth method of dealing with fibroid which I have seen, was one of ]\Ir. Thornton's, the pedicle being of good length, and neither broad nor thick. The temptation to treat it like the pedicle of an ovarian cyst was too great to be resisted. It was transfixed with a double thread tied in tlie usual way, and the tumour cut awaj'. The cut edges of the peritoneum around the stum]> were drawn together b}' the glover's stitch; the stump itself was allowed to drop back into the jjelvis ; the abdominal wound was completely closed, no drainage tube being used ; the patient made H perfect I'ecovery. Rarely will the condition of the pedicle be such as to permit of its being treated in the manner just mentioned ; its shortness, fieshiness, and vascularity forming usually insurmountable obstacles. When, however, it is practicable, the advantages which it afi"ords are manifest, and should not be lost sight of. The fourth mentioned method, is that of complete hysterectomy. Hemoval of the uterus and the tuuiour has been practised with much success by Dr. Granville Bantock, to whom in England is due in large measure the established position which the operation has acquired. There are two accidents which may occur in the performance of the operation, and which need to be carefulh^ guarded against — one is, the wounding of the bladder ; and the other, division of one or both ureters, which are often closely applied to the surface of the tumour. I have several times seen the bladder in great danger of being included in the wire of tlie serre nceud, and in one case the fundus of that organ was so included, and cut away. The simple expedient of keeping a catheter in the bladder, whilst the wire is being adjusted and tightened up, will serve to prevent such an untoward accident. If we bear in mind the fact that the ureters are liable to injury during the operation, we shall be little likely to danuTge them. Such an accident, if unrecognised, would a.ssuredly foul the peritoneal cavity. The open end of the uterine cavity, or canal of the cervix, should be thoi-oughly clean.sed by some antiseptic application, then the cut edges of peritoneum should be drawn together over the tO}) of the stuuip by a continuous suture, in the same manner as the mouth of a bag is closed by a string. The area of cut surface is thus reduced, septic infection is less likely to occur, and .shrivelling of the stump itself is favoured ; shreds of dry antiseptic gauze foi-m the best dressing. The application of some powerful styptic or antisej)tic to the cut surface of the uterine stumj) is, 1 think, ilangerous. T'here is always risk of some of it passing down by tiio feide of the stump into the peritoneal cavit3\ 230 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. It may surprise you to hear tliat I have nothinp; more to say respect- ing the removiil of ovarian cystomata. A good deal of what has been already said applies largely to ovariotomy, but that operation is so well understood, and has been so well nigh brought to perfection, that I think it unnecessary to occupy your time, already too much trespassed upon, in discussing it. I shall only say that to a wider-spread knowledge of tlie ill results of tapping — ill results often shown by the formation of adhesions, and by infection of the peritoneum with jiapillary growths — to a more precise diagnosis, and to a more com])lete asepsis, we must look for a still greater reduction of the already small mortality. UPON THE TREATMENT OF SO-CALLED TROPICAL ABSCESS OF THE LIVER BY FREE INCISION AND STITCHING OF THE ABSCESS-WALL TO THE LIPS OF THE PARIETAL WOUND. By Joiix Davies Thomas, M.D. Lond., F.R.C.S. Eng. I have ventured to invite the attention of the Members of the Congress to the histories of three cases of abscess of the liver, whicli are here briefly reported, partly because, at any rate in my experience, this disease is rare in the southern parts of Australia, and partly because, to the best of my belief and knowledge, the treatment adopted in these cases is rarely, if ever, carried out in India and other tropical countries in which the disease in point is Aery common and fatal. For the notes of the following case, I am indebted to Dr. Toll, of Port Adelaide, under whose care the patient in question was during the A\hole of his serious illness. The detailed notes of the case have unfortunately been lost, and those recorded here are, on that account, somewhat incomplete. My personal knowledge of the case is limited to an examination immediately before the operation, and to the perform- ance of the operation itself, in company with Drs. Toll and Lendon : — Case I. W. B. B., aged 28, was admitted into the Port Adelaide Hospital on Octol^er 2, LS87. The patient had lately returned from the Kimberley goldlields, Western Australia, and during his residence there he had suHered great privations, and had had several attacks of ague. After an illness of several weeks' duration, he came under the care of Dr. Toll. At this time he complained of feverishness, j^ain in the hepatic region, incessant vomiting, cough, and profuse night-sweats. His temperature ranged from 99° to 103 . Upon examination, the \i\ev was found to ])e greatly enlarged in area ; there was considerajjle l)ulging in the hepatic region ; there was also troublesome cough without expectoration, and with no evidences of cardiac or pulmonary disease ; vomiting was almost incessant. C>n Octoljer 2, F saw the })atient in consultation with Dr. Toll, when we arrived at tlie conclusion, that there was an enormous aljscess of the li\(M' present. The correctness of the diagnosis was contirmed by the TREATMENT OF SO-CALLED TROPICAL ABSCESS OK THE LIVER. 231 introduction of an aspiratoiy needle in one of the lower interspaces in the x'ight axillary line ; it was also decided that immediate operation was called for, in order to anticipate a speedy rupture probably into the lung. An incision was made over the fifth intercostal space, tlie pleura was opened, and the diaphragm was found not to be adherent to the costal pleura near the wound. It was then cautiously di^■ided to the extent of about two inches, when the surface of the liver showed itself, tltere beiny, as far as could be ascertained, no adhesions beween the diaphragm at this spot and the surface of the liver. An exploratory needle was tiien inserted into the exposed liver tissue, and pus was reached innnediately. Two strong curved needles were now passed so as to transtix the wall of the abscess in two parallel lines about two inches apart ; Ijy means of the needles, two stout loops of aseptic silk were carried through the abscess wall, so as to loop it up tirmly against the edges of the parietal incision ; the wall of the abscess was then divided to the extent of about three inches, and the escape of pus into the peritoneal and pleui-al cavities was prevented by bringing the liA'er surface tirmly up to the sides of the wound. An enormous quantity of thin blood-stained pus, amounting probably to several pints, escaped ; the cavity of the abscess was gently but carefully cleansed with sponges introduced by long forceps, ttc. ; a large drainage-tube was carried to tlie bottom of the cavity, and the usual antiseptic dressings were applied. The entire operation was carried out under strict antiseptic precautions, including the use of the .spray. For several days after the operation, pyrexia, cough, and perspirations continued ; the dressings were changed twice daily, the drainage-tube being removed occasionally to be cleansed. About the 16th day, the drainage-tube was finally removed, and on the 21st day, he was discharged from the hospital ; ten days later, the wound had entirely closed. When admitted into the ho.spital his weight was 9st, when discharged lOst 71b, and when he was last heard of, he was at the goldfields of the Transvaal "in .splendid healtli," and weighing 14.st 91b. Case II. W. J. D., aged 38, labourer, was admitted into the " Alexandra " "Ward of the Adelaide Hospital, on September 22, 1888. Born in North America, he has visited uiany parts of the world, and has often been in tropical latitudes ; two years of his life were passed in a ship oft' the China coast, but for many years past he has lived in Australia. Twelve years ago he had an attack of dysentery which lasted for three weeks, and ten years .since he seems to have had a mild febrile illness, for which he was treated at the Adelaide Hospital for about ten days. He dates his present illness about eight weeks back, when pain referred to the lower end of the sternum, the right hypochondriac region, and the right shoulder, came on. A fortnight prior to his admis.sion into the Hospital, he thinks that he caught cold, at any rate, he began to spit up blood daily, and he estimates that he has since continued to expectoi'ate every day about half-a-pint of blood-stained matter. On examination, he was found to lie a somewhat spare man, ana*mic, and of .sallow complexion. There was distinct bulging in the right hypochondriac region ; the interco.stal depressions at the lower part of the right chest were obliterated, and the subcutaneous \-eins in this 232 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. region were unusually evident. In the riglit nipple and parasternal lines, dulness commenced at the fourth rib, and thence extended vertically downwards to a point about two inches below the costal margin. Tn the riglit axillary line, the upper line of dulness was at the level of the nipple ; posteriorly, resonance was deficient everywhere below the spine of the scapula, whilst absolute dulness appeared two lingers' breadth below the scapular angle. Over the entire right lung, the respiratory murmui' was weak, but not otherwise altered in front ; posteriorly, the respiratory murmur was not only weak, but was accompanied by a coarse, sub-crepitant rale, possibly friction. Vocal resonance and fremitus were practically normal. On the left side of the chest nothing abnormal could be discovered, except a slight displacement of the apex beat to the left ; there was present also a double basic murmur. In the right hypochondriac and epigastric regions there was a distinct tumour, which projected moderately ; its surface was smooth, elastic, but not fluctuant. Jaundice was absent. No discoverable enlarge- ment of the spleen. An exploratory puncture in one of the lower interspaces yielded blood-stained pus. September 2Ttli, 1888. — Operation by Dr. Davies Thomas, assisted by Drs. Way and Lendon. An incisioii about three inclies long was made a little above the sixth rib, and parallel to it ; at its posterior end another incisioii about an inch and a Iialf in length was made at right angles to the former one ; both were carried down to the rib. When bleeding had ceased, a piece about two inches long of the sixth rib was excised ; the periosteum, however, having been previously stripped oft". Some slight difficulty was encountered in the removal of the piece of rib, in consequence of the existence of anchylosis between the tifth and sixth rib, for a small space at the place of operation ; no reason for the anchylosis was discovered. The costal pleura was now exposed, but had not been opened. An exploratory needle was inserted into the abscess, in order to obtain full assurance that it lay at the bottom of the wound ; this being satisfactorily ascertained, two strong curved needles, firmly set in handles and armed with doul^le loops of strong aseptic silk, were passed through all tlie intervening structures deeply into and through the abscess, so as to include about two inches of the wall ; the needles themselves were then withdrawn, leaving two loops of silk by which the abscess could be firmly brought up to the pai'ietal wound, and held there by an assistant. Tlie loops of silk were inserted parallel to each other and to the edges of the external wound ; the wall of the abscess was then freely incised between the loops of silk which lay about an inch apart. Thick tenacious pus escaped slowly from the large opening made, and the cavity of the abscess was cai-efully cleansed by antiseptic injections, and the cautious use of sponges introduced by means of strong forceps, etc. As adhesions were found to exist between the surface of tlie liver over the abscess, and the parietal pei'itoneum over the diapliragm, and the pleura, it was not necessary to use many sutures for the pui'pose of securing the wall of tlie abscess to tlie parietal wound, but as a measure of precaution, two were passed through the wall of the abscess and the over-lying liver, and the lips of the external wound. The original opening into the abscess cavity was found to have been made at about the middle of the cavity, and as I considered it unfavoui'al)ly situated for drainage, I made a counter-opening in tlie TKKATMEXT OF SO-CALLED TROPICAL AUSCESS OP THE LIVEU. 23."J eighth interspace, in tlie axillary line, and inserted a drainage tu])t; in each opening. The wall of the abscess was rough and irregular, and the interior was partially divided into an upper and lower segment, by a kind of ridge of liver substance. The operation was performed mider the usual antiseptic precautions, including the use of the spray The dressing consisted essentially of a pad oi wood wool enclosed in antiseptic gauze. It would be tedious to report in detail the subsecjuent histoiy of the case ; it will suffice to state that the temperature fell at once to normal, and remained so ; that the cough and expectoration, which before the operation was incessant, ceased ; that the pad was changed twice daily for four days, after which one dressing sufficed for eacli day ; that on the fifth day the sutures were removed, and that the drainage tubes were dispensed with, the upper one on the 14tli day, the lower one on the 19th day. Finally, it is repoi'ted that on the 28th day, the wounds had entirely healed, and the physical signs in the right lung were iiormal. Case III. I am indebted to the kindness of my colleague, Dr. Way, for per- mission to publish this case, and to Dr. Aitken, the House Physician of the Adelaide Hospital, for the notes appended : — G. T., aged 38, at present and for some years jjast a miner, but formerly a sailor, was admitted into the Adelaide Hospital, on Oct. 23, 1888, under the care of Dr. Way. He complained of diarrhoea and dysentery of six weeks' duration ; this was associated with abdominal pain and occasional vomiting. He had sustained a compound fracture of the left leg eight months previously, and from this he had hardly recovered when his present illness befell him. For two years past he has lived in the Barrier Gold Fields District. Upon examination he was found to have an enlargement of the liver, the dimensions of which were as follows : — In the right nipple line from the fourth interspace, as far as two inches below the right costal margin ; in the median line from the cardiac dulness, to about two inches above the umbilicus ; in the right axillary line, the upper line of dulness was at the sixth rib ; and behind in the right scapular line, the dulness began at the eighth rib. There was slight bulging of the lower interspaces over the hepatic region, but no redness of the skin or fluctuation. Jaundice was absent. An exploratory puncture in the seventh interspace, in the right axillary line, yielded pus near the surface. November 2, 1888.- — Operation by Dr. Way, assisted by Dr. Thomas. Incision, with re-section of a piece of the eighth rib in the right axillary line ; pleural cavity opened, there being no adhesion of the diaphragm ; loops of silk passed through the diaphragm and aliscess wall ; the latter was then freely incised, the contents evacuated, the edges of the incision in tlie wall stitched to those of the parietal wound, and the cavity was carefully cleansed. In this case. Dr. Way made an opening and inserted a drainage tub<^ for the pleura in the seventh interspace, about two find a half inches away from the opening into the abscess, the oliject being to prevent infection of the pleura by the discharge from the abscess during the 234 INTEHCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. after-treatment. The opening into the pleura at the site of the original incision was closed by stitching up the wall of the abscess all I'ound the edges of the parietal cut. Tlie subsequent history of the case may be briefly stated. On the eighth day the sutures were removed ; on the eleventh, the pleural drain was dispensed with, as no discharge came through it. Until the eighth day, the tempei-ature rose to about 100° in the evening, and then fell to normal. At present, November 14th, tlie patient n ay fairly be I'egarded as convalescent. CONGENITAL PHIMOSIS AND ADHERENT PREPUCE. By Geo. Talbot Woolley, M.R.C.S. Eng. Hon. Surgeon, Castlemaine Hospital. Before going into tlie technical details of my paper, I cannot help asking my professional brethren, and especially those with large midwifery practices, to pay a little more attention to the formation of the infant, especially with reference to the penis, and to instruct the nurse how to act, in case all is not as it should be, and to utterly ignore any stupid opposition which may be met with, either on the part of the parent, or the nurse ; for I find that the greatest ignorance exists amongst the parents and nurses, as to the proper formation of a baby boy's foreskin. In almost every instance, on a medical man being informed that the infant is feverish, fretful, and always crying, he, as a rule, suggests that there is something wrong with the diet, and that the little one is sufiering from the wind, or some other popular complaint of infancy, arid various suggestions are made, without any material benefit ; but if you enquire more closely, you will often find that the child wets his napkin almost incessantly, that his penis is almost perpetually in a state of erection, and that the watei-, which is sometimes very high in colour, stains the napkin yellow ; and if you look, you will find that the prepuce is so tight that it is impossible to see tlie lips of the meatus, which, wlien they are exposed, will be found to he in a state of congestion. In such cases, measures should be adopted to gradually stretch the orifice of the prepuce, and see if there are any adhesions, and if there are, the morbid conditions will be commensurate with the extent of the adhesions and the age of the child ; for it will be i-emembered, that at a very early age the glanduhe odorifera; begin to secrete a quantity of badly smelling caseous material, and this being, by the adhesions, prevented from being washed away, has to find a habitat for itself, and gradually, but surely, buries itself in the surface of the glans penis, or the under surface of the prepuce, and sets ujj a definite form of constitutional disturbance; tlic origin of which I generally have had to arri\e at by a series of negative deductions, until T began gradually to recognise symptoms peculiar to this condition. CONGENITAL PHIMOSIS AND ADHERENT PREPUCE. 235 In (Munuerjiting tliese symi)toiiis, 1 would like to dniw marked attention to one, wliicii to my eye is pathognomonic of this disease, \-iz., an expression or aspect of tlie face, more noticeable in children of from two to eight years of age, which gives it a peevish or peaky look ; the skin has a shiny, dry, cracked look about it, and there are generally some sores about the nostrils and cornei's of the mouth, which are quite typical and ditterent from the eotiuHon herpes following cold ; and so great an impression has tliis eharaeteristic face made upon me, that T rarely, if ever, make a mistake in my diagnosis. The child is generally ill, feAerisli, with bad appetite and fui-i/ed tongue, and passes urine very freipiently, which is sometimes thick and milky, and .sometimes of a \ery high colour ; lie is generally in pain about the lower part of his abdomen, but is not able to give you any definite account of his condition. In order to illustrate the many and various phases of this condition, T will shortly describe a few typical cases which luiAe come under notice during the last few years, cases which illustrate some very serious conditions, and point to the great importance of every medical man insisting that the foreskin of e\eiy baby boy, whom he has under his charge, can be easily put back, all adhesions broken down, and the tilth cleaned out. Child, jet. 3 years, had been under treatment for over twel^'e month-s for double hernia, worms, consumption of the bowels, and various other complaints, and was gradually getting worse. Got rapidly well after having prepuce, which was contracted, forced back, xevy extensi^■e adhesions broken down, and about a teaspoonful of sebaceous matter, which had eaten into the glans, removed. Child, mt. 2h yeans, treated for over three months for typhoid or low fever ; cured immediately, on being cleaned out. Child, a^t. 18 months, in same family in which three cases of virulent typhoid were raging ; suddenly developed bad symptoms, almost identical A\ith the others, when, in spite of the opinion of the parent that the child had typhoid, I, led by the urinary expression, insisted upon examining the penis, and found xevy extensive adhesions, and quite t^^■o teaspoonsful of secretion. Immediate recoAei-y. Boy, ;et. 8 years, passing almost pure blood per urethram for three days, which entirely sul)sided, with all feverish symptoms, on having adhesions bi'oken down, and foreskin cleaned out. Typical expression. Boy, fet. 7 years, failing in health and losing use of both legs from hips down, got quite well after having extensi\ e adhesions broken down. iStrong facial expression. Boy, set. 20 months, had Ijeen under treatment for intlannuation of Ijrain, bowels and lungs. Got rapidly well on being cleaned out. Condition partly found out 1)V habit of pulling prepuce. 236 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. HE-8ECTI0N OF THE INTESTINE BY A NEW METHOD. By H. WiDENHA.Ai Maunsell, M.D., Dunedin, N.Z. Suigton to the Dianedin Hospital. Witli antiseptic pvecaiitions, make an incision in the median line sufficiently long to enable you to thoroughly search the bowels for the wounded or diseased ])ortion of the gut. Having found the part to be excised, bring it outside the abdomen with about six inches of healthy gut on either side, pack well round with warm large flat aseptic sponges. Clamp the gut in two places — from four to six inches above and below the portion to be excised. Neio Clamp for Bov^el. — Place a small flat sponge across the intestine, about four or six inches from the part to be excised. Transfix the sponge and the mesentery close to the gut with a strong safety-pin ; pass the pin again through the sponge on the other side of the gut, and clamj) the ])in. Better still, have two clam'ps prepared, ready for immediate use, with the sponges sewn firmly to the arched portion of the safety-pins ; the sponge should be sufficiently large to compress the intestine against the pin, so as to effectually prevent extravasation of the contents. The advantages ai-e — its extreme sim])licity, its easy applicability, its innocuousness, and its efficiency, as the pressure can be regulated by the size of the sponge. Neuber recommends a narrow elastic l)and to be passed through a small opening made in the mesentery, close to the intestine, at a suitable distance from each end of the ])iece of intestine to be removed, and tied around the gut to prevent the passage of faices and flatus. I have tried this method, and found that the bowel was injured by the ligature, no matter what care was taken in applying it. Sir William MacCormac, who wrote a very able paper on "Intra- peritoneal Injury " for the Lancet, May 7, 1887, says he has abandoned all artificial clamps, and relies alone on the pressure of the fingers and thumbs of his assistants. I believe an artificial clamp to be necessary, as an assistant's hands are always in the way, and must relax long before the completion of a long operation. When the entire circumference of the intestine is involved in the wound, the bowel must be invaginated, so as to bring the i)eritoneal surfaces into perfect contact all round, and suture them in that jjosi- tion. How is this to be accomplished? When Nature performs enterectomy STiccessfuUy, she invaginates the upper portion of the intestine into the lower, and when the jjeritoneal surfaces have united by adliesive inflammation, the invaginated bowel sloughs ott" with impunity. Let us co])y nature as closely as ])ossible. RE-SECTION OF TIIK IXTKSTIXI': HV A XEW .MKIIKH). .3; I will now, by a series of (lingraius, cndeiivour to demoiistnito the dirterent ste[)s of my oi)eration. Fio. 1. Cut surfaces of both eucls of bowel brought together by two temporary sutures with long ends left intact, aa. One at the mesenteric attachment of the gut, and the other (exactly opposite) at the most distant portion of the bowel from the mesenters'. These temporary ligatvires are very im})ortant, as they secure the proper relatice position <>/ the two cut ends of the gut, and facilitate their subsequent invagination through the opening made in the lower segment of the gut (see Fig. 5). If you examine the gut in a living animal, you will find the blood-vessels pass into it from the mesenteric attach- ment. These divide and subdivide, until they are lost in an invisible anastomosis in that portion of the intestine most distant from the mesentery. I pro])Ose to make an opening here in the lower segment of the gut, through which the invaginated ends of the divided bowel may be dragged by the temporary sutures, and when they are accurately sewn together all round, they can be pulled back into their normal position. The longitudinal slit in the lower bowel, which begins about an inch from its transverse section, is brought together by a continuous suture. By this simple device, the perfect union by suture of a complete transverse section of the bowel, with its peritoneal surfaces in exact ]iosition, and all the knots of the sutures on the inside, can be accomplished. 238 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Fig. 2. Longitudinal section (aboiit an inch and a half long) with tenotomy knife, of that portion of lower segment of gut which is opposite to its mesenteric attachment. This opening should be made about an inch from the severed end of the lower bowel ; its length depends on the size of the gut to be invaginated. In performing this part of the operation, ]nncli up the coats of the intes- tine betw^een the linger and thumb, and transfix with a tenotomy knife. Rimimniiiiniiiniiiiiii iiiiii i{ INTERIOR OF UPPER SEGMENT OF GUT BliilTi 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 iTil 1 1 1 1 1 A ^ ? ( [JiMii nmiHMiii iiillllll lllllllil INTERIOR OF LOWER SEGMENT OF GUT lllllllllllllllllllllllllimn I MM I HI MIIIHIllllMIIIMMIIIIIlTllllllMIMIUM IIIMIIMIIIIIIIIIIIir Fig. 3. Longitudinal section of gut, sliowing a a, peritoneal coat; be, muscular coat; c c, mucous coat ; d d, temporary sutures passed into bowel, and out through the longitudinal slit made in lower gut ; f, mesentery. RE-SECTION OF THE INTESTINE BY A NEW METHOD. 239 Fig. 4. Longitudinal section of intestine, showing the relative position of the diti'ercut layers of bowel, invaginated through the longitudinal slit. From this diagram, it may be seen that the ])eritoneal surfaces are in accurate juxtaposition all round. While an assistant holds the ends of the tem])orary sutures, tlie surgeon passes a straight needle armed with stout horsehair through both sides of the bowel ; the horsehair is tlum hooked up from tlie centre of the iuvaginated gut, divided and tied on both sides. In this way, twenty sutures can be placed rapidly in position with ten passages of the needle. The temporary sutures are now cut off sliort, the l^owel pulled back. The longitudinal slit in tlie lower bowel is closed with a continuous suture, and the mesenteiy brought together with four or five interrupted sutures. 240 INTKRCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. Fig. 5. Invaginated f,'ut, showing the two iieritoneal surfaces in jnxtapositioii all round. A — Needle passed through both sides of the bowel, iiiti'odiicin;) ta-o sutures a a time. .Fig. G. DiAORAM OF liETEACTED iiVT. A -Line marking jun(;tion of both ends of bowel, the peritoneum well turned in, and the .sutures ami knots all inside the gut, making an almost invisible air and wutcr-tiglit joint. ij — Longitudinal slit in bowel, sewn up with continuous .suture. c — Mesentery united l)y interrupted sutures. liEVIEW OF THE RESULTS OF EXCISION OF IIAKD CllANCUK. 241 This oi>eration is applicable to any part of the large or small intestine, and the pyloric end of the stomach may be excised in the usual manner and invaginated through an opening in the centre of the anterior wall of the stomach, sewn up from the inside, and then retracted to its normal position. Sutures for Bowel. Fine silk is recommended in all the text books for sewing up the gut. I find horsehair or tine silk-worm gut far the best. Silk sutures, when wet, are very sloppy to work with. They swell up and cause suppura- tion in their track. None of these disadvantages apply to horsehair or silk-worm gut. " A Fig. 7. AA — Temporary sutures, with euds intact, uniting cut surfaces of stomach and pylorus. D — Longitudinal slit in stomach, made by pinching up its coats between the finger and thumb, and transfixing with a tenotomy knife. Through this opening the invaginated cut ends of the pylorus and stomacli are passed, when they can be sewn up from the inside, and tlien retracted to tlieir normal position. The longitudinal slit sewn up with continuous suture. A ti'ansverse section of the intestine should never be sewn up with a continuous suture, for the following reasons : — (1) The diameter of the intestine is always varying. (2) As the stitches would not all cut out simultaneously, they would form loops inside the intestine, which would be liable to catch, or be dragged or torn out by the onward movement of the contents of the bowel. CRITICAL REVIEW OF THE RESULTS OF EXCISION OF HARD CHANCRE. By M. Crivelli, M.D. Is syphilis a general disease from its beginning ? Does it commence at the instant the virus is absorbed 1 Is the first symptom, the chancre, the sign of an already general infection, or else is it a first local accident — a focus from which the viru.s is propagated to the remainder of the economy ? Briefly, does infection precede or follow the chancre 1 To resolve this question would be to resolve, at the same time, the question of the correctness of the abortive treatment of syphilis, to which it is intimately connected. 242 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. If infection has already spread on the appearance of the chancre, and if this symptom is merely its first manifestation, then ail abortive treat- ments are wrong and useless, there being no advantage in destroying chancre. Evidently, the infection must be local for a time, however short that may be. On inoculation, the virus cannot be absorbed so quickly as to attack at once the whole economy. But how long a timel How are we to recognise the exact moment when, the virus beginning to difiuse from the inoculation point throughout the system, abortive treat- ment becomes useless ? These are questions which we cannot answer, and which will only be decided on the day on which the key to the phenomena may be found — that is, when the pathological microbe of syphilis has been discovered. Interesting works have already appeared, relating to this micro- organism, by Aufrecht, Klebs, Lostorfer, Martineau and Hamonic, Lustgarten, Hugo Marcus, &c., ifec, but the results have not been sufficiently proved, and it is better to refrain from commenting on them, and to wait for new discoveries. In 1857, Eicord said in his lectures on " Chancre," " Syphilitic virus resemble all other s])ecies, whose effects we see without being able to follow the method of their invasion and irradiation in the organism. We see them acting, we recognise them by the lesions they cause, but there ends our knowledge." What Ricordsaid in 1857, is unfortunately true to-day, as far at least as regards syphilis. When syphilis first became known, means were sought to cure it, and the method which was immediately adopted was that which consists of destroying or extirpating the chancre on its first appearance, at a moment when it could be supposed that absorption could not have had time to take place. Thus we see cauterisation mentioned in the 16th century, in the oldest known works on syphilis (Jean de Vigo, 1508, and Blegny, 1696). In 1877, the question seemed to be settled, nothing had been said about the abortive method for some time ; then a work by Auspitz and XJnna, of Vienna (Vierteljahrsschrift fiir Dermatologie und Syphilis, 1877) was published during the year, and received great attention, practically calling the whole subject in question. It is interesting to learn how Auspitz was led to re-consider the eradication of chancre, and to make fresh experiments by the abortive method. He, with Unna, was then making a series of researches on the pathological histology of syphilitic chancre, and on the alterations of texture which precede and accompany the initial sclerosis. They sought together to explain this more or less lengthy incubation of the primitive ulceration, which only begins to become indurated after a few weeks. Auspitz and Unna thought that the virus could enter into the organism from the local lesion by all vessels, and not only by the lymphatics. As for the swelling of the glands, it could not only be caused by the progression of the virus from the iilceration to the nearest glands, but also by a lymphatic, scrofulous, or tuberculous disposition. Auspitz thought that, chancre being really a local lesion, the abortive method should be looked on as a blessing, and he commenced to excise chancres, having this time a therapeutic intent. The observations of Auspitz, 33 in number, were minutely studied by Dr. Leloir, of Lille. The result of this analysis Avas, that ten of the patients presented undoubtedly symptoms of sy[)liilis, notwithstanding KKVIEW OF THE KESULTS OF EXCISION OF HARD CHANCRE. 213 the excision of clianci-e. Nine of these observations must be rejected as being more than doubtful, the jnxtients having k^ft, or having been imder treatment for too sliorfc a period ; this heaves 14 cases on which Anspitz relies as ])roving his conclusions. Out of this 1-t, however, there arc few which are absolutely convincing, as certain patients had previously had chancre (?) Others had only been attended to for some four months, Auspitz considering that a sufficient time; most authors, how- ever, agree with Ricord, that a pei'iod of four months is not sufficiently long to judge if syphilis has completely disappeared. Moreover, these patients left to themselves, after being operated on, have been unwatched for some considerable time, and there is nothing to prove that they did not take mercury, thus retarding secondary accidents, or even causing a total disappearance of any. The folbrwing table shows the residts ohtaiaed by the authors in favor of, '>/■ contrary to, the abortive method : — Sigmund Hueter . . Kuzlinski Auspitz and Uniia Kolliker . . Rydigier Chadz.ynsld Weisflog Jullien . . Bnmm and Eienecker Ottmar Aiigerer Lassar . . Pick Diday Meyer Uh'ich . . Langenbeck CouLsou . . Thiry . . Levfin Caspary . . Klmk . . Zeissl Zarewicb Krowezinski Gibier Maiu'iae . . Spillmau Tomashewski . . Kasori . . Keyes Berkeley Hill . . Quinquaud Terrilloy Mauriac . . Hallopeau 22 7 1 33 8 3 30 28 6 10 12 38 136 13 1 3 2 1 1 2 3 1 1 2 8 8 50 1 2 1 3 1 11 1 460 11 2 ] 14 3 3 7 28 1 5 5 19 102 Failures. 11 10 5 16 4 5 12 32 117 13 1 3 1 1 1 2 3 5 5 1 1 2 8 6 50 1 2 1 3 1 11 1 33i 244 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. If to the above be added ten cases of excision, performed by the author of tliis paper, in Paris and Melljourne, and barren of results, we have the following totals : — Cases, 470 ; successes, 102 ; failures, 34;"). If, however, account is taken of the large number of authors whom ve have not quoted, owing to their not having given precise figures, who utterly condemn excision and cauterization, the number of the 0])ponents to the abortive method would be greatly increased, while the results obtained by the partisans of this method should only be accepted with great caution. Even when successful, no one has a right to affirm that the operation is the certain cause of the abortion of syphilis. Cases in fact have been known, in which manifestly Hunterian chancres have not been followed by any secondary accidents. In my opinion, the question is settled ; and bearing in mind the uselessness and deceit of the aljortive method, I have never excised chancres, except when situated at the end of the prepuce, which were consequently to be followed by ugly scars. There is not a single one of the })retended successes that can be admitted as having had an indis[)utable result. All are open to serious objections, and should they be submitted to a rigid scrutiny, little or nothing would be left in favor of the abortive ti'eatment of syphilis. To diagnose a Hunterian chancre is not always an easy matter. More than one of the most renowned syphilographers could be cited as having been obliged to recognise as insufficient the morphological character of certain chancres, and to prudenth^ await secondary accidents before pronouncing on the case. Could not the partisans of immediate excision, or cauterization, have mistaken occasionally for Hunterian chancres that ulcerative folliculitis, so frequently observed on the penis, and wliich can be accompanied from various causes by a really inflammatory induration '? As for those authors previously mentioned, who pretend that they have excised infectant chancres, which they had diagnosed four days after their appearance, their ol)servations are of no value, and are contrary to all the most authorised and classical opinions on the incubation of syphilis. Amongst the cases which are accounted as successes by the partisans of the abortive method, some are found in which the patients have ])re- viously had chancres. It is a question as to whether these were Hunterian, and if the authors have not excised as initial sclerosis one of those ulcerations of the penis which cause so many errors of diagnosis, when one does not know about the antecedents of the patient. Moreover, the time during which the patients were under observation after the operation, has been in most instances too brief. Ilicord speaks of six months, Auspitz of four, but cases can be found where secondary accidents have appeared twelve months after the first appearance of the chancre. Even the conditions of this period of observation seem to lack the necessary strictness required for the affirmation of a scientific fact, INTost of the patients were not retained in hospitals ; as soon as excision liad been perfonned and healed, they returned to their homes, and only interviewed the doctor several months after. (Syphilitic symptoms may have appeared, and disappeared, during this tiuie. However attentive these patients may have been, the necessary knowledge to recognise and judge these symptoms could not have been theirs. KEVIEW OF THE RESULTS OF EXCISION OP HAUD CHANCRE. 245 The following case will pi-ove how fallacious are the results of the abortive method : — On the 2nd February, 1880, Dr. Ottmar Augerer, of Wiirzburg, excised a chancre eight weeks after infection ; there were no further traces of infection for months. The jintient was married on the 7th October, 1880. All went well at the beginning, but on the 21st April, 1881, his wife miscarried at the sixth month of a foetus in a state of putrefaction. The young woman was a member of a perfectly liealthy family ; certainly, the disease did not come from her side. The husband was then treated with iodide of potassium and hydrai'gyric frictions. The wife became pregnant again, and miscarried a second time on the 16th April, 1882, at about the seventh month. There has never been any symptom of sy])hilis in the mother. Had the patient never married, this case of excision would have been quoted as a positive ])roof of the value of aVjortive treatment ; it proves, however, that a j)atient should not he considered as cured, although showing no signs of general infection. Another class of authors exist who, though not upholding the certainty of abortive treatment, contend that if excision of the chancre does not avert sy})hilis, it causes, at least, the consecutive accidents to be of a more benign nature. It is no inore claimed to destroy or avert syphilis ; but even this simple weakening of the virus is hardly admissible, and this ver}' slight advantage does not seem to be a result of this method, which should be decisively condemned. For if the number of cases on which the partisans of the abortive method rely be counted, it will be seen that they are very limited. The system is not only useless, but seems to be irrational. As a result of the excision of a chancre, there is always a more or less large and always very apparent scar ; while a Hunterian chancre, left to itself, hardly leaves any. The inconveniences that can take place from these large and indelible brands — "unexceptionable witnesses of a disease all would wish to hide" — ought to cause the abandonment of this method, which not only does not effect what its least sanguine upholders expect, i.e., the attenuation of the virus, but is absolutely to be condemned as an operation. As it is impossible, even to an experienced eye, to diagnose the differential nature of a chancre before the sixth day, and as the glands at this time are already generally tumefied, the partisans of excision, to be logical, should not only excise the chancre and inguinal glands, as ])erformed by Bumm and Rienecker, and which is not sufficient, but also excise the glands of the iliac ])it, an operation which is im]jracticable. I think that I have established now that all experiments made up to date to avert syjihilis have been unsuccessful. The great majority of negative results is conclusive, while out of the few successful cases, some should not be accepted without great reservations, and the others cannot stand a severe examination. It can thus be aftirmed, that excision and cauterization are not abortive treatments of sy])hilis. All trials to grapple directly with chancre are useless, because as .say Ricord, Rollet, Fournier, and the great majority of French syphilogra])hers, to whose 0})inions everyone should submit : — " 8y])hilis is a general disease from the first, of which the first numifestation, chancre, shows itself after an incul)ation of about twenty days, when the general economy is already infected and saturated." 246 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. This affirmation is sujiported both by clinical observation and experi- mentation, which agree perfectly. The best proof that can be given of the wortli of initial sclerosis, as demonstrating genei-al infection, is inoculation. Everyone knows that the effect of inoculating a non- sy[)hilitic person, from a Hunterian chancre, is to produce a cliancre ; that the same, inoculated on a per.son constitutionally syphilitic, has no effect ; and that this same chancre, inoculated on the bearer of it, gives no results. These are facts which have been so often verified, that they are admitted by everybod3^ In conclusion, it can be stated that the method of averting confirmed sj^philis has not yet been discovered, and that the best abortive treatment of syphilis (if it can be so called), is still the administration of mercury at as early a stage of the disease as possible. OBSERVATIONS ON THE PRACTICE OF CYSTOTOMY. By Alex. MacCormick, M.D. et Ch. M. Edin., M.R.C.S.E. Hon. Surgeon, Prii;C3 Alfred Hospital, Sydney. I may state, at the outset, that I use the term cystotomy in its widest acceptation, that is, a section of the bladder for any purpose whatever. I purposely avoid the nse of the time-honoured term lithotomy, as a inisnomer, for we do not cut the stone, we cut the soft parts and remove the stone. I venture to plead for greater accuracy in our terminology. Some justification for attempting a more accurate use of terms, is, I think, to be found in the fact tliat, with an increased variety of 0})erati\'e procedures in connection with the urinary organs, there lias arisen a necessity both for general terms to express the broader, and pai'ticular terms to express the more particular features of such operations. Now cystotomy is manifestly a good general term, hitherto unwari-antably restricted in its interpretation ; while lithotomy, though sacred by usage, is, as I have said, a misnomer, and does not express the special features of any operation. I may venture to indicate how I think consistency and utility in nomenclature might well be attained. I think the term cystotomy ought to be used as a general term as I have above defined it, while if a special term to signify cutting for stone be required, tlie term lithectomy would be preferable. Lithectomy could then be further specialised as cysto-lithectomy, and asnephro-lithectomy, according to the site of the calculus ; or according to the site of the operation, as supra-pubic cysto-lithectomy, median perineal cysto- lithectomy, and lateral perineal cysto-lithectomy. In taking as the subject for my pajier the practice of cystotomy in its wider sense, I make no pretence of treating it exhaustively. Its scope is too wide to be adequately treated in any single paper such as this. At first, indeed, it was my intention to take up the subject of supra-pubic cystotomy alone, but, at the request of our Secretary, I have included some remarks upon the subject of cystotomy in general. OBSERVATIONS OX THE PRACTICE OF CYSTOTOMY. 247 Few of its departments ai-e better fitted to exhibit the advance of the science and art of surgery, than tlie surgery of the bladder. It is not here chiefly that the triumphs of antiseptic surgery are so marked, though, no doubt, it has contributed largely to the result ; but, independently of antiseptics altogether, there has been a widening of the area, so to speak, of surgical interference, and an ever-increasing variety of procedure. I shall avoid long tables of statistics, and will try, as much as possible, to base my preference for the adoption of any o[)erative method upon anatomical and physiological grounds. Varieties of the Operation. Looking at a vertical mesial section of the body, it immediately becomes manifest that there are two safe routes into the bladder — one above the pubes and the other below, through the ])erinieum ; or through the rectum in the male, or the vagina in the female. By safe, I mean gaining access to the interior of the organ without })assing through the peritoneum. The rectal operation has been given up by surgeons of the present day, on account of the persistence of fistula afterwards in a great many cases, although ])lenty of room is gained by this method. Of vaginal cystotomy, I shall not here speak. Practically, there are only three operations now practised on the male to obtain access to the interior of the bladder, (1) supi'a-pubic, (2) lateral perineal, (3) median perineal. I think these three operations, with a little modification according to circumstances, will meet all requirements. The median operation, as practised at the present day, is more an external urethrotomy than a cystotomy, as the bladder itself is not incised. Choice op Operation. It is an exceedingly difficult matter to lay down definite rules for the choice of an operation, in any case of bladder trouble where cystotomy has been decided upon. Many operators have a favourite method to which they will submit all patients, but this is not fair to the patient, nor is it fair to the method selected, for each operation has some special advantages, and special disadvantages, according to circumstances. Supra-pubic Cystotomy. The position of the wound in this operation is said to be a faulty one, from the point of view of general surgical principles, on account of the l)ad position for drainage, but this is the worst that can be said of it. To show that the track of the wound is limited by fasciie, though not so eff'ectually as in the low operation, I shall refer to the arrangement of the transversalis fascia in the front wall of the abdomen, to which Braune, in his "Atlas of Topographical Anatomy," has drawn particular attention. He shows that the transversalis fascia, opposite the semilunar fold of Douglas, splits into two layers — an anterior and a posterior. — (See also Liverpool Med. Ghir. Journal, Jan. 1885.) The anterior layer passes down behind the rectus abdominis, and is attached to the upper border of the pubes towards its posterior aspect. The posterior layer when traced downwards is seen to be carried to the superior aspect of the bladder by the urachus, and becomes continuous 248 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. witli the recto-vesical fascite and the capsule of the prostate- Of the correctness of the above description, I liave satisfied myself by careful dissection. These two layers of fasciae enclose a space which is called the porta vesicae of Ketzius, or the pi"e-vesical space, and it is into this space, and not into the sub-peritoneal space, that the bladder rises when distended. In the operation of supra-pubic cystotomy, it is this space that is entered; and here the bladder can be opened to a considerable extent in the middle line, without the operator running any risk of wounding the peritoneum, or even of opening the sub-})eritoneal space, so long as the incision is confined to the middle line, and does not extend backwards beyond the urachus. I may mention here an interesting fact, pointed out by Mr. Harrison, viz. : — " When there is a fracture of the pelvis, with extra-peritoneal rupture of the bladder by a fractured pubic ramus, it is evident that the urine will be discharged into the pre- vesical space ; and, sup])osing the bladder to be drained by a perineal incision, this incision will be very unlikely to drain the space of its contained urine, which will remain mixed with blood, and in contact with the fractured bone." — (" Surgical Disorders of the Urinar}' Organs," p. 28.) Dr. Weir, of New York, reports a case illustrative of this, where he drained the blaxlder through the perineum, after making an incision above the pubes. — (^New York Medical Record, March "iOth, 1884.) Mode of Performing the Operation on the Adult. The hair having been shaven off the pubes, and the skin rendered aseptic, anesthesia is jiushed to complete relaxation. Then a red rubber catheter is introduced into the bladder, and the urine drawn ofif. The bladder is now to be gently distended with a solution of boro- glyceride (1 in 40). If fermentation is going on in the bladder, it ought to be gently washed out with boro-glyceride solution before finally injecting it. The quantity to be injected should be between nine and ten ounces for an adult, and from half an ounce to two or three ounces for a child, according to the age. In distending the viscus, I prefer Thompson's bladder syringe to any other, on account of the exact way iu which you can gauge the amount of resistance. The catheter having been removed, the penis is tied with a small piece of elastic tubing, A rectal bag shovild then be greased, and introduced into the rectum just beyond the internal sphincter, and then distended with warm water (10 or 12 ozs.) An incision of sufiicient length, according to circum- stances, is made in the middle line in front, stopping at the symphysis pubis. The thin pale line, corresponding tothelinea alba, is then looked for, and the incision deepened along this line between the edges of the recti with as little teai-ing as possible. The edges of the recti being gently held asunder Ijy retractors, the anterior layer of the transversalis fasciffi is exposed, and should be pinched up with forceps near the lower end of the wound, and incised, and then the deposit of fat in the pre- vesical sjjace will be exposed. Next, by means of the left index finger, with the pulp uppermost, the fat and the reflection of tlie peritoneum should be pushed upwards out of the way. A sharp hook or a loop of silk should be made to fix the bladder to the anterior wall of the abdomen in the ui)per part of the incision. Then an incision is made into the bladder large enough to admit the index finger with which to OBSERVATIONS ON THE PRACTICE OF CYSTOTOMY. 249 examine the interior of the organ, and to judge of the requisite Icngtli of incision in the bhidder wall that may be necessary. Here, I think, it is of the greatest importance to disturb the tissues in front of the bladder as little as possible. The soft tissues behind the pubes should not be interfered with; and, above all, the bladder should not, when it collapses, be pushed before the examining finger, and its fascial connections disturbed, because, if this be done, it is evident that the chances of extravasation will be much increased as the two layers of the trans- versalis fascia will be extensively separated. If the cystotomy is being done for stone, it can be placed in the most favourable position, and removed with a pair of forceps, taking great care not to injure the bladder wall, or to bruise or tear the edges of the bladder wound ; it is always better to enlarge the wound with the knife than to tear it with the finger. The most suitable kind of forceps are a pair of " lithotomy forceps," with a lock like midwifery forceps, and the blades should be applied in the same way as in obstetric practice, taking great care not to include the wall of the bladder. The parts should be then well washed with boro-glyceride solution. The question now arises as to whether the bladder wound should, or should not, be sutured. I think everyone will agree to suture the bladder, if the urine and viscus itself be fairly healthy. The best suture to use is fine catgut, and the best method of suturing is Gussenbauer's or Lembert's. The sutures should be ])laced close together. The superficial wound is then closed, and a drain put in the lower part of the wound, down to the bladder wall. It is very difiicult to sew up an extra-peritoneal wound or rupture of the bladder, so as to render it watertight. In an intra-})eritoneal wound or rupture, the smooth serous surfaces can be brought so accurately together as to render the wall of the bladder perfectly watertight ; but in the foi-mer case, it is much safer to provide a good drain for any urine that may leak through. In any case, where the bladder wound is at all large, I think it is good practice to suture it carefully, and if the mucous membrane be unhealthy, or fermentation is going on in the urine, to leave room for a drainage tube at the lower end of the wound. A catheter in the urethra, unless in an exceptionally tolerant subject, is not advisable. In the case of adults with very unhealthy urine, I should be inclined to use a method described by Dr. Keyes, of New York, for draining the bladder through the perinseum — {Journal of Cutaneous and Genito-Urinary Diseases, July 1887, Xew York.) He uses a large red rubber catheter, and ])asses thi-ough its lumen a piece of twine, bringing it out at the eye, and then with a needle he passes the twine in through the eye again, and out through i)oint of the catheter, until a knot, previously ])laced on it, catches. The part of the twine hanging from the ti]) is then threaded into the eye of a silver probe, which is turned up at the point ; then, as in the operation for median cystotomy, the membranous part of the urethra is incised, making just enough room for the catheter to be drawn through. The probe is pushed through the incision along the knife into the groove of the staff, in the membranous part of the urethra, and then into the bladder, and is caught through the supra- pubic incision, and by the aid of the string, the catheter is pulled into the bladder, the string is cut short and withdrawn, when the catheter can be fixed at the proper length inside the bladder. 250 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. I have performed tliis operation (siipra-pubic cystotomy) four times within the last two years. The first case was that of a boy seven years of age, on whom I performed tlie lateral perineal operation on December 23, 1886. On making the usual incision, and passing the finger into the bladder, I found a stone, very rough, and as I consider, very large for a boy of his age. On passing the forceps, I had no difficulty in seizing tlie stone, but I judged, from the position of the handles, that the blades were sejmrated to such an extent as to be likely to cause a great deal of tearing if extraction were attempted ; thei'efore, I considered it safer to withdraw the forceps. I had then to choose between crushing the stone or removing it above the ])ubes. I decided on the latter method. I got one of my colleagues to pass the index finger of the right hand into the bladder through the perineal incision, and with it to push the anterior wall of the viscus up behind the pubes against the lower part of the rectus muscle, so as to push the anterior wall of the bladder up into the pre-vesical space. I then made an incision as for supra-pubic cystotomy. I did not see the peritoneum at all, and I found the finger a most convenient and effective guide. On opening the bladder, I kept it forward with blunt hooks. The stone was removed, the forceps being much aided by the finger in the bladder. I sutured the bladder carefully with catgut, put a drain in the lower part of the abdominal wound, and left it in for forty-eight hours, the bladder being drained through the lateral incision. The abdominal wound healed by first intention, and the patient made an uninterrupted recovery. In young or thin people where, for some reason, after the lateral or median perineal oj)eration, it is deemed necessary to open the bladder above the pubes, the finger of an assistant acts as an admirable guide, and by judicious pressure on the anterior wall of the bladder, he can push it uj) into the pre-vesical space as reatlily and as effectively as if the bladder and rectum were distended. My three remaining cases were those of children of one and one-sixth, two, and two and a half years respectively. In these three cases, the operative procedure was the same, and the supra-pubic method was chosen in the first case on account of the youth of the patient ; in the second and third cases, on account of the size of the stone, which was first measured bi-manually with one finger in the rectum and the other on the front wall of the abdomen. The bladder in the first case was injected with about one ounce of fluid ; in the second and third, with two ounces. The bladder wall was not sutured. A drainage tube was used in the superficial part of the wound only, and the upper part of the abdominal wall was sutured. The drainage tube was always removed in forty-eight hours ; and in the first case, although urine trickled along the drainage track for the first two days, it did not prevent union by first intention in the greater part of the wound, which was completely healed in ten days. In the other two cases, the wound healed in twenty- one and eighteen days respectively. In neither of these cases did I use a rectal tampon, but instead, I got an assistant to push the bladder upwards and forwai-ds gently with his right index finger in the rectum. In the case of children, I consider it is quite unnecessary to use rectal distension, as it is more likely to cause injury to the rectum, and it may even thrust the bladder to one side, and the rectum itself thus present in OBSERVATIONS OX THE PRACTICE OF CVSTOTOMV. 251 the al>doniinal wound ; and, furthermore, the finger can give the operator great assistance in the removal of the stone, by making jjressure from below.— (Vide " Deutsche Zeitschrift fiir Chirurg.," Bd. •28th, 1 ct 2 Hft.) I have made reference to the use of the l)i-nianual, or recto-abdominal examination, under deep aniestliesia, in the diagnosis of stone, especi- ally in children. This method of examination has not hitherto received sufficient recognition in the literature of the suV)ject. I have been in the habit of practising it for .several yeans, with the greatest advantage. Thu.s, I have been enabled to detect a calculus not bigger than a split pea in the bladder of a child of fourteen months, upon whom I was unaV)le to pass the smallest sound. Another great advantage of this method is the information which it elicits as to the shape and dimen- sions of the stone. Indications for Supra-Pubic Cystotomy. (1) For stone in very young children. — I think the supra-pubic method is the best operation in very young children. I advocate it on two grounds, as being {<(), the best operation anatouiically ; and (A), the safest. (a) In regard to the anatomy of the bladder in the child, I think there is a tield open for further investigation. The be.st descrii)tion of it that I have found, is in Dr. Symington's " Atlas of the Anatomy of the Child." S3'mington gives a vertical mesial section of a male child at birth, and the amount of urine in the bladder was estimated at one drachm. The orifice of the urethra, in this case, was at about the level of the upper border of the pubic sym])hysis. [n front, the bladder extended forwards and upwards, in contact with the symphysis and the anterior abdominal wall, against which it lay, until within one centiuietre of the umbilicus. The anterior surface of the bladder was entirely uncovered by pei-itoneum, and there was no tendency to the foruiation of a jieritoneal pouch between the bladder and the anterior aV)dominal wall. Posteriorly, the peritoneum i-eached as low as the level of the urethral orifice. In all the sections of a child at this age, the orifice of the urethra was at the level of the upper border of the pubic symphysis. Whether the bladder was empty, or distended, its anterior surface always lay in close contact with the anterior abdominal wall — this relation corresponding more than in the adult, with its tubular tlevelopmental character. The anterior surface was entirely uncovered by peritoneum, and was of a triangular shape, tlie base of the triangle being at the pubes, the apex towards the umbilicus, and the lateral boundaries corresponding to the hypogastric arteries. The bladder, in all cases, lay in contact with the lower two-thirds of that part of the anterior abdominal wall between the umbilicus and the sym[)hysis ])ubis. In a section of the body of an infant, three and a half months old, Symington found that the uncovered part of the bladder corresponded to about a quarter of the distance between the umbilicus and the pubes with the bladder empty. In an infant, seven months old, where the bladder contained one ounce of urine, the uncovered part of the bladder occupied nearly half the distance between the umbilicus and the symphysis. 252 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. In boys of from four to six years, he found tliat when the bladder was empty, its relations to the peritoneum differed in the contracted and relaxed conditions. When contracted and empty, the peritoneum came down behind the .symphysis. When relaxed and empty, the membrane was reflected on the bladder above the symphysis. When distended with from two to three ounces, the distiince between the reflection of the peritoneum and the .symphysis was over two centimetres. From a perusal of these facts, it will be seen, that in the child the jDeritoneum covers the bladder more extensively towards its base than in the adult, and therefore, the distance between the base of the ])rostate and the reflection of the peritoneum is I'elatively less. The facts, also, make clear the relation of the anterioi' surface of the bladder to the anterior wall of the abdomen and to the peritoneum. Another very important point displayed in the sections is the small capacity of the infantile bladder. In an infant, seven months old, the bladder was pretty fully distended when it contained only one ounce of urine. In Holmes' "System of Surgery," Sir Henry Thompson says, that the most frequent cause of death in children, after lateral perineal cystotomy, is ])eritonitis, due presumably to injury to the peritoneum during extraction. Xow, I hold that this would be much less likely to happen in the supiu-pubic operation. (b) If we look at the statistics given by Sir William MacCormac, and published in tlie British Medical Journal of March 19tli, 1887, where he collected all the cases of supra-pubic cystotomy he could find in London and the ])rovinces, from January 1885 up to that date, we find thirty-three cases of this operation in children under fifteen years of age, with no death; in Mr. Twynam's paper, in the October number of the Australasian Medical Gazette, last year, we find a list of twenty- eight cases of fifteen years and under, with one death. Assendelft has done the high, or supra-pubic operation, one hundred and two times, with two deaths. If we comjjare these statistics with the statistics of the lateral opera- tion, as given in Holmes' "System of Surgery," we find that, for children .sixteen years and under, the death-rate is about one in sixteen. So that, judging from these statistics, tJie high operation is much the safer one in young children. Still, I would not advocate its performance in all cases of children under fifteen, because, after five years of age, with a small stone, I do not know of any easier or more rational operation than the lateral. But if the stone be of such a size as to require a large incision into the parts at the base of the bladder, and any roughness in the handling, I think the supra-pubic route the safer. The size of the stone, at this period of life, can be very easily determined by the bi-manual examina- tion, and then the operator should weigh in his mind the difficulties, and give the benefit of the doul)t in favour of the supra-pubic. Up to December 1886, I liad not thought much about supra-pubic cystotomy in children, and I was always in the habit of doing the lateral operation; the results were always favourable, and beyond a little delay in getting into the bladder of a fat child of two years of age, I never had any difficulty or com))lication; but I am sure that one not practised in the lateral })enneal operation, and who practises antiseptics carefully, can more easily and safely gain access to the bladder above the OBSERVATIONS ON THE PHACTICE OF CYSTOTOMY. 253 pubes than below, in. cliiklren of five years and under. I know of several unpul)lislied eases, below this age, in which the perineal opera- tion had to 1)0 abandoned, and a still greater number of cases in which considerable difficulty was exi)erienced, and time spent, before the interior of the bladder was reached. Passing over the difficulties and complications that may occur during and immediately after either oi)eration, we must not forget the after-effects of tiie two operations. In the high operation, the only bad after-effects that may occur in children are, a tendency to hernia and the possibility of a fistulous opening, both of which chances are very remote. But, after the perineal operation, there are the chances — (1) Of incontinence of urine (I have seen several cases of this, and I think it is always due to an over- stretching of the sphincter vesicte, from an insufficient incision). (2) Of impotence. (3) Of sterility. (4) Of fistula. CONX'LUSIONS. (1) I would advocate the supra-pubic operation for stone in all children under live or six years of age ; between six and sixteen, I should be less decided in my choice, but should, if the stone were of a con- siderable size, prefer the supra-pubic. I think, however, that it would be much better to perform lithola|-axy for small stones in children, if one had suitable instruments, but I would limit this operation to very small stones. (2) For large stones in adults. — No one will dispute the great advantage and safety of the high operation over any other method in cases of very large calculi in the adult ; neither will any one dispute the advantages of the lateral perineal in any case of small stone where a cutting operation is decided upon. In this field of practice, litholapaxy has come to rival the lateral perineal so much so that, according to Sir Henry Thom])son, all calculi that cannot be crushed ought to be too large to be safely removed by the jjerineal roitte, and therefore ought to be removed by the supra-pubic route. He even states that the high operation is, in his opinion, preferable to crushing for calculi, which, though not of the largest size, are extremely hard. Most surgeons have not the dexterity in crushing that Sir Henry Thompson has accjuired, and although most men can crush a small stone with perfect safety, I have seen very disastrous results at the hands of very good opei-ators in attempting to crush a large stone. According to Sir Henry Thompson's dictum, a stone is small, medium-sized, or large. A medium-sized stone is one which measures about one inch in each of two of its smallest diameters, anything below this is a small stone, and anything above is a large stone. Any calculus one inch or less in its two smallest diameters no one would hesitate to crush, but stones above this, except in the hands of very good manipulators, would be more safely removed by a cutting operation. The pi-ostatic urethra itself can be dilated to nearly one inch, without much risk of injury, and the incision of the prostate would give three-quarters of an inch more room, so that a stone one and a quarter inches in each of two of its smallest diameters could be removed by the lateral perineal route without any tearing of parts, so that I still hold that in the hands of judicious operators the lateral operation ought to retain a place. Sometimes in cases of small stone, it may be desirable to perform cystotomy, as in patients of a phosphatic diathesis with 254 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. intense purulent cystitis, so as to allow the bladder rest by a thorough drainage for a few days. Such cases are better treated by a lateral perineal cystotomy. (3) For tumour of the bladder. In cases of tumour of the bladder, supra-pubic cystotomy has achieved very wonderful results ; but as there is generally a very considerable amount of doubt in these cases, as to the nature and attachments of the growth, a niedian perineal cystotomy in the first instance would clear up all doubt, provide a good drain, and in no way interfere with the subsequent supra-) )ubic cystotomy, if the case could not be dealt with through the perineal opening. Here, Thompson's sound will be of the greatest advantage as a guide to the high incision, and to ^Jush up the bladder wall. (4) For enlarged prostate, with chronic cystitis. Supra-jnibic cystotomy has been performed by Thom])Son and others in cases of enlarged prostate with chronic cystitis, where instrumentation had become very troublesome. By McGill, of Leeds, it has been performed with the object of removing portions of the enlarged prostate. He reports three cases in which the results were very satisfactory. AVhen cystotomy is performed to ]n-ovide for a permanent drain, I think most surgeons would prefer, when possible, to drain through the perineuui, when, if necessary, portions of the prostate could be removed. (5) For foreign body of an irregular shape, that cannot be broken up or extracted by a lithotrite. (6) Oases of impassable stricture for catheterisation from within [British Medical Journal, No. 1, 1S84). (7) In cases of anchylosed hip joint. (8) In deformed pelvis, from rickets. (9) For some cases of encysted stone. (10) In cases of pyo-nephrosis, where there is doubt as to which kidney is diseased, this operation might be performed as a ])reliminary, in order to decide which ureter was discharging pus cr blood, before any more heroic ]»rocedure, in the way of nephrotomy or nephrectomy, should be decided on. In some such cases, of couise, the endoscope might render exploratoiy cystotomy unnecessary, but in other cases, the amount of pus or blood )night obscure the examination by that instrument. Median Perineal Cystotomy. This operation in the adult is the easiest and safest route to the interior of the male bladder, but it has the great disadvantage of giving only a small opening. I will describe the operation as I practise it. The i)ati(!nt, having been ana3sthetised, and a median staff passed, is placed in the lithotomy position. The staff being held by an assistant, the surgeon passes the foi-efinger of the left hand into the rectum, and places its tip, with the pulp upwards, where the staff enters the apex of the prostate, so that he can feel the groove tin-ough the intervening tissues. Then, taking a long narrow bistoury in the right hand, he plunges the knife, with the back downwards, into the tissues of the perinseum, half an inch in front of the anus, through the raphe, and exactly in the middle line. With the finger in the rectum, he avoids wounding that viscus, and guides the knife into the groove of the staff at the apex of the prostate, and with a sawing motion, incises the floor OBSERVATIONS OX THE PKACTICE OF CYSTOTOMY. 2oO of the membranous urethra for fully lialf an inch close to the apex of tlie prostate. The knife is then withdrawn, and at the same time is made to cut upwards to give sutiicient room, avoiding the bulb if l)Ossible, so as to lessen the amoxint of haemorrhage. A Wheelhouse's goi-get, passed into the groove of the staff, is guided by it into the bladder, and over this the left index hnger of the oi)erator can easily enter the bladder under ordinary circumstances. By making bi-manual examination, the whole of the inner wall of the bladder can be brought into contact with the examining finger. Dolbeau, who made careful dilatations of the prostate and neck of the bladder experimentally wdth a dilator, has shown that the neck of the bladder cannot be distended to a diameter greater than twenty to twenty- four millimetres, without producing lesions of it, and of the prostate ; so that no stone more than four-fifths of an inch in diameter can be removed by forceps without laceration. — (" Ashhurst's International Cyclop, of Surgery," vol. VI., j). 258). The great field for this operation, however, is not for the removal of calculi, but for the purpose of exploring and draining the bladder. Considered from an anatomical point of view, it is perfectly correct ; it cuts no important structure, there is no haemorrhage if the incision is not made to wound the bulb, and the drainage is perfect. This opera- tion is very useful as a preliminary to any of the other operations in any doubtful case of bladder trouble. I have i)ointed out above its advantages as a preliminary to the supra-jjubic. Mr. Harrison points out how more room can be gained, if necessary, by passing a curved probe-pointed bistoury into the bladder, along the pulp of the finger, and then cutting with it downwards and outwards to the prostatic capsule, and enlarging the wound in the same direction as the knife is with- drawn. I think it is everywhere admitted, that this is the easiest and safest way of entering a bladder for the purpose of exploring it. In obscure diseases of the bladder wall, it will become more common, not only for the purposes of diagnosis, but for the purpose of treatment. Through it the bladder can be thoroughly drained, and put at complete rest, as can also the urethra, so that the mucous membranes get time to recover ; just as in the female, where dilatation of the urethra for the purpose of exploi-ing, when no cause is found for the bladder trouble, often cures the disease completely by paralysing the sphincter and giving the viscus rest. I have performed median cystotomy twice for chronic cystitis, which had persisted for years, and each time with great benefit to the patient. Besides for the purposes of exploring, removing tumours of the prostate and bladder, draining the bladder in cystitis, and of prostatectomy, Mr. Harrison practises this operation, in a somewhat modified form, for certain cases of irritable stricture, where instrumentation is apt to be followed by a great deal of febrile excitement, and where an internal lu-ethrotomy alone would be dangerous. His intention is thus to stop all danger of sepsis, or urethral fever, by keeping the urine from contact with the diseased urethra. Let me quote a case, to show the advantages which followed complete removal of urine from contact with a raw or diseased urethral mucous membrane : — C. P., aged 26, was admitted, suffering from an organic stricture of the bulbous portion of the urethra. The stricture was the result of 256 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. gonorrhoea, wliicli lie had contracted when he was about 16 years of age. It had been dilated to the size of a No. 7 on several occasions, but always recurred very rapidly. With some difficulty I succeeded in getting a whalebone bougie into his bladder, and this was followed by a severe rigor. To make the history short, sutfice it to say that after a great deal of trouble, I succeeded in dilating gradual]}^ to the size of a No. 9, but after almost every operation he had a rigor, even after the gentlest handling. He was discharged from the hospital, with instruc- tions to come regularly to have an instrument passed. This he partially neglected to do, and soon had to be admitted again for further treatment. He being so subject to rigors, 1 determined to perform internal urethrotomy, and in addition, to drain his bladder tlirough the perinseum. His stricture being still large enough to admit a Thompson's urethrotome, I divided the constricted part completely along the floor of the urethra, passed a large median staff, entered the urethra at the apex of the prostate, as in median perineal cystotomy, next passed a probe into the bladder as a guide for a No. 12 gum elastic catheter, which I used as a drain, draining the urine by means of a tube into a vessel by the side of the bed. The patient escaped all constitutional distui'bance after the operation. At intervals of three days I passed a large sound through the divided stricture, and washed out the urethra from the front with antiseptic solution. At the end of three weeks, the bladder drain was removed, and in a short time the urine flowed through the natural channel. The patient left the hospital with Nos. 12 and 14 soft catheters (English scale), which he was instructed to have passed at intervals of fourteen or twenty-one days. I saw him nine months after, when he described himself as being more comfortable than he had been for ten years. He has since married. The advantages claimed for this operation are : — (1) Avoidance of grave constitutional disturbance ; (2) Avoidance of risk of extravasation ; (3) The stricture is more pliable after, and less liable to contract. Lateral Perineal Cystotomy. This classical operation has not been changed in any essential respect since the days of Cheselden. It is one of the best planned operations in surgery. Although its scope has been greatly limited by the practice of litholapaxy, and the supra-pubic operation, I hope there will still be a })lace left for it in the future. An able, brilliant, and kind-hearted old surgeon of my student days was used to express his ideas about Heaven in the following words : — " Heaven is a place wheie all the good i)eople are cutting the bad people for the stone." As I have already said, I make no pretence of travelling over the whole field of the practice of cystotomy. The subject is an exceedingly important one, for I suppose few operations can claim to do more in the way of relieving human suffering, when judiciously carried out. I have only to thank you for the courteous attention wdiich you have given to my observations on this subject. suPKA-i'umc Li'nioTOMY. 257 SUPRA -PUBIC LITHOTOMY. By J. Tremearne, M.R.C.S. Eng. Tlie safest and most effective method oi operating for stone has lieen lately a subject of contention, ferforni the high operation on patients advanced in years, and suffering from large stones, the woi'st cases in fact, where probably diseased prostate or some other complication exists, which would necessarily entail fatal results if the latei'al operation was attempted. We may arrive, however, at some idea of the advantage of one opera- tion over the other, in cases where the bladder has been cut into above the pubes, when it might have been through the perinseum, and vice versd. In August 1877, I cut into the bladder, above the pubes, after performing the lateral perineal operation for a boy of ten years old. A calculus tilled the bladder and projected it forwards, so that it felt large and hard like a cricket ball at the lower part of the abdomen. Nothing could be done through the jjerineal opening, but with the addition of that above the i)ubes, it was easy to break up, and clear out the bladder thoroughly. After the operation, oidy a few drojis of water escaped through the abdominal opening, but not any after the third day, and by the seventh, the abdominal wound was healed. Urine ceased to come through the perineal opening on the twenty-seventh day, and the wound healed shortly afterwards. The abdominal opening in this case would have been quite sufficient had it been a little larger, and that it was absolutely necessary for the removal of the calculus, was quite evident. In the case of J. C, a sharebi'oker, aged 47 (reported in the Australian Medical Journal, for July 1883), all the usual symptoms of stone were present, and he was compelled to pass water every hour. He had been badly affected by spasmodic asthma for 18 months, and could not lie down, but slept sitting in a chair at night. After an unsuccessful attempt at crushing, the supra-pubic operation was i)erfornied, and a cystine calculus of 2| ounces in weight removed, as well as small bits of cystine gravel. A tube was put into the wound, and allowed to remain for a week, and the usual means of drainage adopted. Shortly after its removal, the opening (juickly closed and healed. Five weeks after the operation, the patient had increased 30 lbs. in weight; and asthma, whicli pi'eviously distressed him, had neai'ly disappeared. Robert F., aged 45, a big, burly, red-faced, and very nervous man, with hsemorrhagic diathesis, had the .supra-pubic operation performed two years ago. A stricture affected the greater part of the urethral canal, s 258 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. which was so sensitive, that on attempting to introduce a sound, violent rigors came on and prevented its being properl}^ treated. The symptoms, however, became so urgent, that it was decided to opei'ate, as stone of some kind had been felt in the bladder. Through the unusual amount of fat, and bleeding from the incision, many minutes elapsed before the anterior wall o£ the bladder was seen projecting forwards on the point of the catheter, when it was liooked up, cut into, and a calculus removed about one and a-half inches in length. Another stone, somewhat smaller, was found embedded in the upj^er and front part of the bladder. This might have been missed had the bladder been cut into from below. The incision into the bladder caused profuse haemorrhage, although the ])lexus of veins in front was not wounded. During the night, two assistants, one on each side of the bed, held the wound compressed between the foi-efinger in the bladder, and the thumb on the outside of the abdominal wound, and thus almost entirely commanded the bleeding. A great amount of blood was, however, lost during the tirst twenty-four hours, but afterwards recovery was rapid, and within three weeks he was quite well. The stricture was dilated at the time of the operation, and gave no further trouble afterwards. Had the lateral operation been undertaken, I believe the bleeding from the bladder could not have l)een controlled so effectively as it was through the supra-pubic opening. Edward C, aged 30, was operated on in July 1887. A stone (which was found afterwards to weigh exactly one ounce) could be detected readily, and might have been removed by crushing or cvitting. He had previously made up his mind to have the high operation and no other, attempted. The opening above the pubes had closed, and he was up and well eight days afterwards. Lateral ]ierineal cystotomy has been performed only six times in the Creswick Hospital. Three of these were young boys ; one, 5 years old, died the same night ; another, aged 3 years, has now — seventeen years after the operation — involuntary micturition, and impotence ; while the third is the case mentioned, where the supra-pubic incision was combined with the lateral. One of the adults, W. B., aged 26 years, had the stone removed, but the perineal wound could never be healed, and he remained until his death, twelve months afterwards, with a iistulous opening. John N., aged 36 years, had for six months frequent and severe attacks of bleeding from the bladder. ISTothing definite could be detected (although he was several times under chloroform) except a slight roughness at the top of the bladder. Lateral cystotomy was jterformed in 1877, when a small stone was discovered to be deeply encysted in the wall of the bladder. It was not easily removed, as the fistulous opening leading to the stone w*as only one-eighth of an inch in diameter. Little bleeding took i)lace at the time of the operation, but several sudden bursts occurred afterwards, and on threeor four occasions death from syncope was apprehended. Had the supra-pubic o})eration been performed, the bladder could have beeii examined more thoroughly, and means used to check what nearly ended in fatal hajuiorrhage. John O'S., seen in September 1878, had all the symptoms of stone in an aggravated form. There was an opening in the perinfeum, through which urine constantly dribl)led. He stated that lateral lithotomy was })erformed on him two months before, and a stone over an inch long removed, but the wound had not healed, and his pain, relieved only for SUPRA-PUBIC LITHOTOMY. 259 a few (.lavs, had returned more violently than ever. A stone, 1^- inch long by 1 inch across, could be readily made out in tlie bladder, and after several attempts with a powerful Jithotrite, was removed by crush- ing, when the wound healed. It would have been impossible to miss this calculus had the bladder been opened from the front. Thomas J., aged 19, was seen by me only once, about an hour before his death, when a distinct projection was noticed over the pubes. After his death, T made a post-mortem examination of the body. A stone lay in a pouch in front of, and nearly as large as, the bladder itself, causing an ai)pearance of the bladder like an hour glass. The opening from the • bladder into the pouch was only sufficient to admit a No. 2 catheter into the cavity, so that a sound passed through the urethra into the bladder detected nothing. The calculus could have been removed easily by the supra-pul>ic operation, but in no other manner. Comparison of the Two Operations. Supra-inihic. (1) Cutting into the l)ladder from above the pubes may be attempted by a novice with but little fear, as long as he keeps in the centre line of the abdomen. (2) There is no danger of wounding important parts, except the reflection of the ])eritoneum over the upper and front part of the bladder, but the peritoneum will rarely be seen if the rectum and bladder are distended (as Sir H. Thompson advises), and even if wounded, it seems of no great consequence as long as the accident is noticed, and immediately attended to. In boys, the anterior fold of the ])eritoneum is higher, on account of the abdominal position of the bladder, and no distension of the rectum is necessary. Of 478 cases collected by G. Dallas, and mentioned in the Eacydopcedia of Surgerf/, in 13 the peritoneum was wounded, and with a fatal result in one only. (3) The bladder is opened from the front, which is its safest aspect ; some veins over the bladder bleed freely when divided, but they can be plainly seen and cutting them avoided. (4) The opening can be made as large as necessary for any stone or tumour to be removed. The bladder can be examined more satisfac- torily, and an encysted calculus or morljid growth (vvhicli might not have been detected through the ])erineal ojtening), removed. Haemorr- hage can be controlled without difficulty, as no arteries would be divided ; the bladder can be readily washed out, and the wound treated anti- sejjtically. There is no fear of tistula, incontinence of urine, wounds of rectum or i)rostate gland, impotence, or any other of the risks of the ])erineal incision. Although extravasation of urine is mentioned as one of the dangers, it has been rarely, if evei-, reported as occurring, and by draining the wound both extravasation and septic poisoning are pre- vented. The bladder can be kept free from any accumulation of urine or pus, and the patient's body dry, by adopting the syphon principle. Some threads of candle wick, aV)Out two yards long, are doubled in the middle, and the fold pushed through the wound down into the Vjladder as far as it will go. The ends of the upper portion of the threads com- municate with a liottle of fluid (solution of ])erchloride of mercury, 1 in 5000), raised above the level of the wound, whilst the lower portion passes across the |iatient's 1)ody, and ends in a vessel ]:»eneath the bed. The solution runs down along the thit-ads and through the wound, s 2 260 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. carrying off all ]iuriilent matter with urine, as soon as either appear in the bladder. The wick, except abont an inch or two in the lower part of the wound, is covered with india-rubber tiil)ing ; and waterproof sheeting, with a small hole cut in the centre (to allow of the passage of the wick into and out of the bladder opening), can be placed over the abdomen. Lateral. (1) In cutting through the periuieum, considerable skill is required; the incision may not be low enough, or too low, or too much inwards, &c. (2) The urethra may not be opened as far back as it should be. The artery of the bulb, the jjudic artery or the I'ectum, may be wounded, or the prostate cut through. The prostate may be torn from the membranous portion of tlie urethra, a misfortune which sometimes happens when children are operated on, in the attempt to get the finger into the bladder. (4) There is but a limited amount of room for grasping and removing a stone, or morbid growth, and for examining the bladder. (.5) The ditticiilty of controlling secondary lifBuiorrhage; (6) The chances of incontinence of tirine, wounds of rectum or prostate gland, impotence, &c. TWENTY SUCCESSFUL CASES OF SUPRA-PUBIC CYSTOTOMY. By Henry O'Hara, F.R.C.S.I. Senior Surgeon, Alfred Hospital, Melbourne. In February 1887, the House Surgeon at the Alfred Hospital published in the Australian Medical Journal, the notes of my first case of supra-pubic cystotomy. The operation was performed successfully for the removal of a large oxalate of lime calculus, and I claimed for the operation, that it was the first recorded in Australia. I was so struck with the wonderful results obtained by the lithotomists of the old world, in their revival of supra-pubic cystotomy, that I determined to perform that operation whenever a suital)le case should present itself. I had removed several large and small calculi by the lateial method, both in private and hospital practice, with varying success; and I always felt, that in jierforming ]ierineal section, one was working at a great disadvantage (more jiarticularly in cases of enlarged prostate gland), and how helpless one necessarily was in arresting the hemorrhage that might occur in the region of the prostatic plexus. The pressure that is usually apjilied, in the form of a " plug," not only prevents the flow of urine through the wound, but itself very soon becomes a source of septic mischief, and holds foetid material for the prostatic veins to take up. Where chronic disease of the bladder is the result of the long continued irritation, caused by a stone within its walls, I hold that it is as necessary to give free exit to its contents, as is the drainage of a purulent cavity in any other region of the body. If, therefore, in the removal of a stone from the bladder, I find that no vesical trouble exist, I allow the wound to heal as speedily as possible; but on the other Jiand, where a collection of putrid urine has accumu- lated for a length of time— a semi-paralysed bladder having merely rid itself of overflow — I keep a portion of the wound in its walls open witli a drainage tube, until I have satisfied myself that the mucous lining has TWEXTV SUCCESSFUL CASKS OF SUPRA-PUHIC CYSTOTOMY. 261 regained its noi'uial condition. During the operation, the peritoneum in this region can \>e kept up with very gentle traction. Tlie anterior wall of the bh\dder is its thickest and strongest part, and therefore, more likely to Ileal best. In children, the anterior bladder wall is quite uncovered by i)eritoneum, although tlip bladder lies high up in the abdomen. Its posterior wall is, however, covered by peritoneum down to the level of the prostate gland. The blood-vessels, sup[)lying the parts anterior to the Ijladder, are not of a formidable nature. In my tirst operation, December 8, 1886, I took two ste})s, which at that time were laid down as im])erative, viz., inflating the rectum, and suturing the divided walls of the bladder ; and experience has since taught me that neither step is necessary — in fact, that both are some- times harmful. I can quite realise how a partially diseased bladder would tear (when the knife was applied to it), from the intense pressure of a rectal bag. I cannot see any advantage in filling the bladder to bursting-point, and I never inject more than six ounces into it m3'self. It can be kejit well away from the peritoneum, if the catheter or sound is properly held in i^osition. The sutures, I consider, only retard the healing process, causing sloughing of the parts, and I do not think there are any authenticated cases where no urine escajted through the wound, after the operation had been completed. I have quite discarded the use of sutures. Having had the pubes shaved, and 6 ozs. of some antiseptic fluid injected into the bladder, I make an incision from two to three inches in length in the median line, commencing about one inch above the pubes. This incision is carried down to the bladder. I then introduce my finger into the wound, and guided by the sound inside, I feel for the anterior superior asjiect of the bladder. Having seizevd the wall in this position, I make an opening through it about one inch, so as to admit my finger. If the stone be a large one, the incision can be lengthened to suit the operator. The stone is now grasped with a lithotomy forceps, and extracted, and the patient j)ut to l)ed. jVIy reasons for making the incision so high up are, because it is less likely to be encroached upon by the urine, if that fluid be drawn off every two hours for a few days; and also, because the superior surface of the bladder is more likely to be healthy, being further away from the part where the stone has been lodged. And I find it a good plan to hav'e the patient's bed raised at the head, so as to have him lying on an inclined plane. Should a stricture of the urethra co-exist with stone, the operation of internal urethrotomy can be done at the same time as the lithotomy. I did Teevan's operation in three cases, with good i-esults, leaving a drainage tube in the bladder to drain off the urine while the urethral wound was healing. In conclusion, I must express my delight at the results of supra-pubic cystotomy in chronic cystitis, where incrustations form on the bladder wall. It is not my intention to occupy your valuable time with the notes of every case. I have made out a tabulated list, giving the age of patient, the complication (if any) co-existing, the duration of time from date of operation until healed, and the result when healed. The shortest cure was 9 days, in a Chinaman at the Alfred Hospital, and the longest 236 days, the patient's bladder being in a very diseased condition. 262 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. s & T) 1 •a •3 1 -s ■3 1 •3' •3 •3 u i d 3 3 3 U o o o 5 o -2 2 a 1 >< i| > ta «" o| S > rti- n f ^ -^ 5S ^ ^ ■~ 1 •1 '^ » - a a ?5 I. .3 — ■3 c5 " ^ g ■3 a s -»J 3 rt 2? rt '^ 0^ ':; p. «T3 '~ . -= 2 1^ 1 OS 1 i-5 r^ "1 '3 to ^ 5" s" s K ;^ > ^ < fi •i ^ O 5. tE O "- O S Co "S ^ c s » il •St; a "3 s 3* 8 1 a ^ -S'S (2 S 5 k; ^ 2 -3 S -=-3 okI '3 ^ " =.-■3 s 2 o to "Ul a .2 ci §2 x2 Is o 3 '3 ■S 2 S S fi to 3 5 Is 5 3 ■3 3 ■3 > ^ ^ 3 2 a a 0) P-B IfJ -3^ 2 a rt 1 II 33 3 a -g 313 a i 2 ^ a: « I2 fe a"* » 00 +» il Hi S s 1 W H K K W a t5 M fW -p ^ e4 21 o to o "o o 3 ^ M _5 To '3 to '3 ?o .5 -a S a O to CO ^ CQ C 00 CO ,_^ So-^ 2" 2 1 to o 2'§ to * ■ 1 w « oT a ! s 1 1^ J o <« — >, S-'' 9 "S 1 S" a <: 5 o o 1 o a -2 "3 rti tpj •550 ■2 1 "3 3 'E..2f-a 1 a ;«( o ■^ " "c v^ ° E E D >5 ^' - C3 Ch D E » u a i~ to - -- 11 To il 3-3 . A "5 o It TO to x Hi a. -t^ 5 H -< O _c ^-5 3. t.l'- ^ •M ^ c _2 ^ 5 B4 1 i d 2 2 a §" 3 » T3 5 «■ — bo 2 11 ^ *^ ;-. 0) » a> 1 a o o >5 a 15 a S a as c 'A < to o •i -« r- C-l V- 01 CO 1- to ^ •o ■i> o s^ cc 10 (^J "' 5 d C ■-5 cd d Q P3 Q K ^ «fj ffi S5 S aj d (<' -»i d ►^ d d •-3 d U < i-i Cl :-3 -t* ■o to I- CO C5 ^ j^ O TWENTY SUCCESSFUL CASES OF SUPRA-PUBIC CYSTOTOMY. 263 H J 3 TJ "-<* f^ r— ' -d •3 •^ 'd a> J) J) x ^ S j5 ;- ^ s 3 a a » o O o O o O O o h- >>^- = « -; m S s S s >» "■ 3 •r si o c^ ?o = J^' -2 '— TO l^g ■s-^ a <2 b) rlS-- '£ 'S "^iS" tt ■^« •r ^ jj-O ::_'-. (W .n a _!s to ':il^ ^ ? 2 ^ e i| 2 ^ o < ill 1 .3'^ — . s 1 ^ a >-._ 13 c ^ 9 S "S'i >i 1 !l if = « 1 II 1 1 - = ^- o til" c is "Si; 1 "to _a s "2 a ^ jQ y -m^ ?x ^ -; r^ » • 'g r* -. ^ '^ zp-tJ ^ .2 I^S" rt 2 £ g ^ rt ^•r«= = 3 yi it 'w g-/j ^rH a5 H « tB < i5 W M h-t IJ z -*^ .- ^ i^ ^o ^ c X 32 c3 C or ;^ !* to a b < lit to to CD To in o TO a o 5 ct s 1. ' :^ 5 i" ,2 f •s cs a' 2 o '^ o o Ch 13 e-( t5 t) la Pu -2 ^ z ce z 03 "3 2 5 ■-3 .s ■•3 ^ >> _ >> DO M y ^ » « P, ^ ■^ a ■■s to rt g. O » ? ij o i -g *3 2 s 2' J3 S o _^ >-. 3 .c 33 55 o 03 U la o '/^ a- ^ S5 o ^ ^ j_ ^ -* ^ o « TO •^ 4ai CO '~ ^ °3 ;~ P (^ e.; >j ;5 rZ p; If 6 C^ la d 1-3 S < H d CO ^^ ^. ■i 1^ CO O ■Zi •« O 264 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. NOTES ON LATERAL SPINAL CURVATURE, WITH SPECIAL REFERENCE TO TREATMENT. By G. Affleck Scott, M.B., CM. Edin., Maryborough, Victoria. Tliis subject seems to me worthy of attention (1) Because the complaint is so common. (2) Because it is so often not noticed, so often not considered, and so often left to nature's own treatment, or nature's own neglect. And yet it causes a great deal of discomfort and ill health, a good deal of pain, and ill severe cases, sometimes complete invalidism and occasionally death, and the effects will probably be still more marked on posterity. I have been surprised to see how much lateral curvature there is in our country districts, often very slight, certainly, and frequently discovei'ed only when examining the chest for other reasons, but always sufficient to justify treatment, preventive and curative. The object of treatment is to restore the vertebral column to its normal shape, and to prevent its re-assuming the abnormal. Removing the cause is, of course, the preliminary step ; treatment being followed out as indicated. Drawing or writing in bad position, inequality in length of limbs, etc., will require to be remedied. Preventive treatment, as regards the spine itself, we need not fully discuss here. The chief points seem to me to be : — (1) Gymnastics for girls as well as boys. (2) Free natural movement and exercise to be allowed to children. (3) Give young gii-ls no corsets, and older girls very light ones. (4) For shop girls, and all young people who have to stand much, allow sitting down whenever possible. This is an important point, and seldom, if ever, attended to. (5) Introduce a reform in the system of teaching writing. This is looking forward, i)erhaps, too much, but it is sometimes well to be radical. It is impossible to sit over a desk, as at ju'esent taught, with the paper straight before one and write in the orthodox slope, without great risk to spinal rectitude. It is suggested to abolish the slope altogether, and let us all be taught straight or back hand. But why should not the paper be placed at an angle of 45° towards the left side, that would still allow an orthodox sloiie, and the spines would be grateful, wliatever the caligraphist might be. It would be a question whether the latter method would tend to give us Laputan inclination of the eyes. But either of the two reforms would be better than the present system of endeavouring to induce spinal curvature in the writing class. The cause being removed, the next question is, whether to allow the vis medicatrix to complete the cure, or to take its place ; the former course is, perhaps, usually followed, but considering the number of cases seen, and seen too in a pretty advanced stage, its adoption is repre- hensible ; l)esides which, the curvature is, of itself, a predisposing cause of further curvature. Having premised then that .sometliing be done, we have a bewildering number of difi'erent modes of action recommended, ranging from ab.solute rest to extreme exercise ; from making instruments do all the treatment, to discarding instrumental support altogether. In severe ox LATKUAL SPINAL CURVATURE. 265 cases we may, perhaps, simply follow out Noble Smith's instrumental treatment, wiien instrumental treatment is necessary; that we leave, as we are discussing cases of medium severity. Sayre's jacket deserves notice. As a curative agent it cannot act, but in cases of caries, where movement is to be prevented, it makes an admirable splint, and by giving rest, allows nature to cure the cai'ies, but the curve remains in statu quo. It is recommended in very advanced cases, where there is no hope of improvement, and where prevention of further deformity only is aimed at. Such cases, also, I cannot dogmatise upon, but should think them excessively rare ; besides which, the jacket ])revents the use of what muscle there is left, and Smith's apparatus should answer at least as well even in the worst cases. Heavy instruments of all kinds, of which several have been invented, have all the same drawback, besides putting too heavy a yoke upon the patient. But instrumental treatment is only necessary in severe cases, which are comparatively rare. The slight and medium cases (Vjy far the more nuuiei'ous class), may be treated without spinal supports at all, and among all the different instructions, th*^ matter is much simplified if we rememljer that the kernel of the treatment is to make the muscles which have allowed the deformity undo the deformity — and then prevent return of the deformity. Cases where the muscles are inca])able of so doing, come under the head of severe cases, re(juiring instruments, but they are probably not so numerous as supposed. The two I'equisites in muscular treatment are rest and action: — 1. Action {a) of one set of muscles more than the others, to undo the ileformity ; and {h) general, to keep the body in tone. 2. Rest [a) of these same muscles, to prevent fatigue which would leave their last state worse than their first ; (/>) of the body generally, to prevent general fatigue. It seems very simple, and the beauty of it is, that it is as simple as it looks. No fixed rules could be laid down as regards either rest or action, the amount of which must be regulated according to ertch individual case — amount of curve, strength of muscles, strength of body generally. &c., but the princiide is easily laid down. 1. As Regards Rest. Its advocates have gone all lengths, even to lying down — if I mistake not — in bed, for long periods up to one or two years. The failure of this need excite no surjn-ise. Two debateable points arise : — [a) Whether the amount of rest should be regulated by the patient's feelings — the system of resting when tired — or whether a fixed daily time should be set. As a rule, I should certainly say the latter. A j)atient is a highly unreliable mechanism, and nine out of ten would not rest till over-tired. The time fixed would, of course, vary ; in moderately severe cases, probably two hours twice a day would answer well. (6) Whether the supine or prone position should be adopted. The supine presses too much on the spinal column, besides having the great disadvantage that each motion of the head, as also the act of rising up again, tends to roundness of the shouldei-s, which is an evil. The prone position avoids these evil.s, but only if supervised ; otherwise, there is risk of roundne.ss of shoulders, as I have seen occur. The great advantage of the prone position is, that every movement of the head is 266 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. beneficial ; but if the head droop, as it often does, the result is to do passively, what movements in the supine position do actively, i.e., produce round shoulders. Verral's couch admits of this, and a well- padded or cushioned couch is pex'ha])s preferable, with no special mechanism, where tlie cushions are arranged so that at rest, the head will not bow the back ; and during movement, allow of beneficial action on the curve. Finally, the patieiit should have a chair, whose back fits the lumbar curve, to sit in at any time when fatigue is threatened, besides the fixed daily time of recumbency in the prone position. This, then, fulfils the requisites as regards rest ; as regards other restrictions, in an ordinai'y case very few are necessary. Tennis is allowed by some surgeons, but I think the quick strokes in all attitudes and positions a risk, and should forbid it. Riding, j)robably, has little efifect either vay, and may be allowed ; and ordinary work, except stooping at a table, Avriting, or even drawing, need not be forbidden if the evil position be not taken up. All this is, however, only precautionary against over action, and in no way cures the curve. That is done by the second muscular requisite, viz., action. 2. Action. Noble Smith's work, and the article in Heath's " Dictionary of Surgery," give good directions as to exercises which may be performed, and which it would be tedious to recapitulate. We might note, however, the evil of acting upon the dorsal muscles on the concave side of the curve, in the hope of thereby undoing the curve. Use them, and the result is as seen in Fig. 1. Certainly, the spines of the verte- brae come into the middle line, but the rotation will be increased, and the deformity of ribs and scapula made worse. The action required is exactly the converse — traction on the spinous processes of the vertebras from the convex side of the curve, so as to undo the rotation. To effect this, I follow Noble Smith's plan, modified, I think, by Chiene : — Patient sits on a chair with pelvis fixed by band round chair, then with I'ight arm crossed in front of breast and left arm behind back (in right dorsal curve, of course), with the hands holding hand- pieces fixed to elastic bands attached as seen in the Fig. 2, traction is made upon both elastic bands at once, beginning with two or three pulls once a day, and gradually increasing the number as required. Ordinary 4-inch elastic bands answer well. The mode of action is seen by reference to Fig. 2. The pelvis being fixed, each contraction of right arm acts upon muscles from sternum to arm and arm to spine on right side, and draws vertebral spine in a direction away from the middle line, but iindoing the rotation ; also, the left arm contractions tend to diaw sternmn in tlie direction of arrow, towards the left, thus also heljdng to undo the deformity caused by the I'otation. The result bears out Smith's remarks on the subject. But now, with difiidence, I touch a farther note on the treatment, not having had the advantage of extraneous help, M'hich I should be relieved to get ; as however much we admire heterodox theologians, a heterodox, and especially a youthful hetei-odox practitioner, is justly viewed very critically. My fathers will, I know, be lenient, and my brethren courteous. INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. * 266 267 * INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Fiq. I. To shew result on Vertebrae of acting on muscles on concave side of curve. a. Lateral Ciu'vature per se. h. Same after such action ; Spinous Process approaches middle line but rotation is increased. Fig III. CL. ' 'J ^"- 6. To shew result on Vertebrae of acting on muscles on convex side. a. Curvature as before. 6. After action, rotation undone, but Spinous Process not brought nearer middle line. ON LATERAL SPINAL CURVATURE. 267 We are usually left at this point, but it seems to me that to stop here rejieats precisely, though in a lesser degree, the error we have already condemned. When we concluded tliat something should be done Vjeyond simply removing the cause of curvature, we considered the vis medicatrix insufficient of itself. We have now reached a })oint where we have, by treatment, undone the rotation — at least, to some extent — but the lateral curvature remains untouched, and we leave the vis medicatrix to correct it. This same vis seems to me to want help here, too, and it was this, as well as the incompleteness of the treatment already described, which caused me to enquire as to whether nothing more could be done. The object of treatment is, as said, to undo rotation, and to undo lateral curvature. And I submit, that the vertebral column is not one individual, but it is a congregation of 25 separate individuals, who can all move separately, as well as together. We have seen the error of trying to cure curvature by dragging the spines to the middle line, and we have seen how the opposite is the rational ti-eatment. But the effect of the rational treatment is seen in Fig. 3, the rotation is undone, but the vertebra remains as far from the middle line as ever ; and, as it is not our object to end with a spinal column, showing an example of lateral curvatiire without rotation, there must be some movement of the vertebra as a whole towards the middle line. Now, if we can effect thi.s, as well as the undoing of the rotation, and especially if we can get the two processes to go on simultaneously, a great advantage will be gained. If a patient be sitting up — or even lying down, though this to a lesser extent — any exercise, such as we have already discussed, acts at a disadvantage. If you press a number of discs one against the other, to move any one of them is ditficult ; and if you wish to move a dorsal vertebra, to do so with tlie cervical and dorsal sitting upon it above, and the dorsal and lumbar giving counter jiressure below, is not an easy matter, but if you can free the vertebra from its ovei'-aflectionate neighbours, and leave it a little elbow-room, it becomes easy. The two advantages seem to me to be combined in the method of utilizing the old-fashioned extension process by hanging, plus the use of electricity. The method of extension has unqualified condemnation from most surgeons, and, if it means the old fashion of making of the patient a pendulum, justly so; but there are extensions and extensions. The objections are — (1) That it puts too gieat a strain on the cervical portion of the spinal column. (2) That the ligaments, and perhaps muscles, get stretched by extension, become relaxed when the extension is taken off, and fall back into a worse position than before. As regards the first objection, I submit that it depends entirely how nnich extension you exert. If the arms be supported also, and if the extension be only sufficient to have the patient's heels just off and the toes just on the ground, the good desired is obtained, and no risk to the cervical region incurred. As regards the second objection, I beg leave to differ. The muscles do not get stretched, nor do the ligaments. The ligaments on the convex side of the curve are stretched without the extension which, in fact, relieves their tension. The ligaments on the concave side are not tense enough, and the straightening of the spine only makes them so ; and the 268 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. amount of extension sufficient for our i)ui'i)Ose does not come within measurable distance of risk of stretching ligaments or muscles. For extension, 1 do not use a tripod, but had a tetrapod made; the head pad fixed from a pulley in the centre, but the arm pads separate. I have arm-}nt bands attached to pulleys on opposite legs of the apparatus, which allow of the arms being separately raised or depressed, as well as different direction of muscular contraction as desired. Noble iSmith says that extension needs to he very powerful to have any effect. "To illustrate this fact," he writes, ]jage 10, Ed. 1888, " let us take a stout piece of copper wire, or a thin iron rod, and bend it to represent the spine. Then hold each end with the fingers or with ])incers, and endeavour to straighten it by stretching it lengthways. The difficulty is great, we are working at a mechanical disadvantage, and })robably will find it impossible to pull it into a straight line ; but support each end, and press laterally with a finger against the curve, and with much less expenditure of force, the desired effect will be produced. This fact is of course not new, and no one would have thought of trying to straighten the wire in any other way than by lateral pressure, but the argument has not to my knowledge been hitherto api)lied in discussing the treatment of the spine." But, while diffident about disputing authority so great, does not the argument seem fallacious? This copper wire or iron rod is one bodv, it cannot represent the spine, which is many members, and what may be jiredicated of the one, is not necessarily true of the other. Suppose we laid out a string of beads or a piece of elastic, curved to represent the spine, no one would dream of straightening that by lateral pressure, or in any other way than by extension. Not, of course, that a string of beads could represent the spine ; it would be difficult to find a mechanical arrangement which would represent the muscles, ligaments, discs, articulations, bones, &c., which are factors in keeping the form of the spine, but the beads may throw a doubt on the validity of ai-guing that what an iron rod does, so also does the spine. Besides this, practically, 1 think we find that slight extension has a very decided effect. Place a patient erect but not extended, and ajiply the electrodes of an ordinary Faradic battery (mild current) over the rhomboids, and feel the motion of the spines; then extend slightly, and api)ly the electrodes again, the difference in response iid onset and progress, a fatal result could have been averted. Still, under all the circumstances of the case, we believe that we were fully justified in the adoption of extreme surgical measures. 288 INTEKCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. A FEW OBSERVATIONS ON SOME CASES OF CANCER OF THE BREAST, WITH A TABLE OF FORTY- SEVEN CASES. By F. MiLFORD, M.D. Lecturer ou Surgery, Sydney University. In the year 1877, I read before the Medical Section of the Royal Society of New South Wales, a short paper, which I called " Observa- tions on some Cases of Scirrhus Cancer of the Mamma." This was afterwards published in the Australian Practitioner. As the subject is therefore not entirely unfamiliar to me, I trust I shall not bore you in continuing a record of some few more cases. That locality has a great influence on the prevalence of cancer, has been shown by Haviland, who has searched the Registrar-Genei-als' reports throughout England for the priuci[)al habitats of the complaint. It is not known in the Arctic regions or Frigid zones ; is not common in the Tropics ; but is more often found in large cities than in country places. The investigation committee, who are using their utmost exertions to become intimate with the Ijistory of cancer in England, state they only know of one case originating in a person who has lived 1000 feet above sea level. They are of opinion that the character of the soil and subsoil influence its presence. I beg to show you a table compiled from the records of the Registrar- General, showing the num):)er of deaths taking place in Sydney and suburbs during the years 1880 and 1885 inclusive, and the proportionate number of males and fejuales dying from cancer. I lind that in the city of Sydney, 1 female dies in proportion to 42 -8.5 of deaths from other causes. In the suburbs, 1 dies in proportion to 58-53 from other diseases ; showing the much greater liability to the disease in the town, than country. The average mortality of city and suburbs among females is 1 to 50-7. The average mortality in males in the city of Sydney is 1 to 64-9 ; in the suburbs, 1 in 81-7 — 1 death in 73-7 cases of both town and country. The proportion is also thus seen to be much greater in the city, among males, than in the country. The proportion of deaths from cancer among females, during the six years, is much greater than in males. While 1 female dies out of 50 with this complaint, 1 male out of 73 only succumbs, or nearly 3 females for 2 males. In my 1877 paper, I stated that throughout New South Wales the mortality among males and females was 1 in 59-5, In Sydney and sui)urbs it was, during the years 1880 to 1885, 1 in 66*19. It devolves upon us as guardians of the public health, if possible, to devise prophylactic measures to prevent the attack of this complaint, and it will undoubtedly repay us to ascertain what is the best mode of tx-eat- ment after it is implanted in the living tissues. There is little doubt that the disease is chiefly induced by injury to the i)art, whether that be caused by constant irritation or sudden violence. In inquiring the liistory of a patient — sliould we find that she OBSEIIVATIOXS ON SOME CASES OF CANCER OF TJtK BREAST. 289 has a oancerous inheritance and an eczematous rash, or a liard scar from a wound, or nodule — the result of a blow, or has been in constant intercourse with a cancerous ])erson — the question might arise, would we bejustihed, as a j)rophylactic measure, in removing the breast? In any case with a history of cancerous inheritance, I think it will be necessary to recommend your patient to take the greatest care of tlie mannnary glands, to prevent these being injured and exposed to sudden changes and vicissitudes of the weather. Should a patient pi'esent herself to a surgeon with a tumour in the breast, his first duty will be to ascertain whether it be of a malignant character or not. Having satisfied him- self it is a cancer, his next question should be, what is the best mode of treatment? In our present imperfect knowledge of the disease, we are still sure that if left uninterfered with, the disease will go on from bad to worse, until death closes the scene. I am not aware of, nor do I think there is, any record of a s]iontaneous cure of cancer. My nearest experience is recorded in my 1877 paper, in the case of Ellen J., aged 40, who lived three years afflicted by the disease, and had early secondary deposits in the lungs. 8he had an ulcerated hai-d scirrhus tumour of the left breast, which sloughed, the whole of the gland coming away, and the i-esulting ulcer then healed ; but this was after the whole of the system was more or less aflfected, the left lung being solid from cancerous deposits. We are satisfied, therefore, that if left alone — should she not die early from some other cause — the disease must eventually kill her. Hence, in the present state of our knowledge, it will be our duty to ascertain whether she be in a fit state to submit to an operation of a curative nature, to entirely rid her of the complaint ; of a palliative nature, to modify the effects of the disease ; or one for the purpose of simply prolonging life for a short time, by preventing hfemorrhage, resti-aining discharges, or relieving acute pain. We should carefully weigh the benefits likely to follow an operation, and the risks. There are some surgeons much in favor of the operation, others prejudiced against it. In 61 cases quoted by Paget, which were not operated on, but underwent palliative treatment, 29 lived from 3 to 20 years, while the remaining 32 died at between 6 and 30 months. He gives an average of two years' life to encephaloid growths, of four years to scirrhus. According to Gross, 146 cases had come under his observation who.se history he could trace subsequent to the operation. The duration of life in these cases was an average of 5 years and 9 months — a considerable advantage in favor of an operation. He does not, how- ever, say whether the operation was intended to be curative or palliative. Gross himself is a believer in the curative 2~>ov< of a thorough operation undertaken in the early stages of the disease, during which the whole of the breast, skin covering it, and axillary glands, together with the pectoral fascia, should, he thinks, be removed. Erichsen, in his 1888 edition, and others, support him in similar terms. The extirpation of the tumour can only be done by knife, caustics, or cautery, and, if thoroughly performed, may rid the patient entirely of the complaint. The knife is, of course, the most efficient of these measures. u 290 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Gross claims by his operation to cure 30 per cent, of his cases, if taken at an early stage, before the disease has spread far into the neighbouring tissues. I see no reason why this mammary form of the disease should not be eradicated from the body, when the labial so frequently is. We all know how many useful lives have been saved by the simple Y incision in the lower lip affected with epithelioma. As a curative or palliative measure, or for the purpose of preserving life by preventing haemorrhage or relieving intense agony, it is the duty of the surgeon in some cases to operate, first explaining to the patient or her friends the motives that influence him. It remains with her to choose whether she submit or not. In mentioning the operation to his patient, it would not be correct for the surgeon to ignore the immediate dangers of it, which according to Gross, as stated in his paper on " Carcinoma of the Breast " — published in the April number of 1888 of the International Journal of Medical Sciences — constitute a mortality of 1 to 7 from the immediate effects of the operation. In my paper of 1877, I record that out of fourteen cases operated on, only one died from the immediate ettects, or rather, from an attack of pleurisy coming on on the third day after it ; the other thirteen survived, these cases undergoing secondary operations at the return of the disease in or about the neighbourhood of the cicatrix of the first operation. This is an improvement on Gross' statistics, but I have here a table of forty-seven cases, all of which have had the mammary glands excised, and many the axillary glands as well. In recording these cases, I have endeavoured to get as much information with regard to them as was possible, but I am sorry to say that in many instances I have not been able to procure a history subsequent to the operation, and in some cases a most imperfect and unreliable one previous to it. I give as nearly as I can the name of the patient, whether married, single, or widow; the age when disease was first perceived by the patient, the date when it was first perceived, date of first operation, by whom performed, date of return of disease, date of second and subsequent operations, by whom performed, date of death, age at death ; if alive, age at present, and state of health, with the duration of the complaint. I am indebted for twenty-three cases to the courtesy of the authorities at St. Vincent's Hospital; to Dr. MacCormick, of the Prince Alfred Hospital, for fourteen of his own cases ; and to Dr. Goode for seven of his. In these forty-seven cases two deaths only occurred from the immediate effects of the operation, one in a woman (No. 33 of the series) aged 42, who had a large f ungating encephaloid mass projecting from the mamma, which bled freely, the operation being undertaken to prevent further haemorr- hage. She died exhausted on the fifth day. The other patient died during the administration of chloroform before she was touched by the scalpel. Leaving this case out, one patient only died out of forty-six ; taking it as belonging to the series, one out of 23*5 is the proportion, a marked improvement on Gross's one in seven. The duration of life of a patient, who has suffered from the disease and borne the operation, can be exemplified in the table; but only in those OBSERVATIONS ON SOMK CASKS OP CANCER OF THE I3REAST. 291 in wliich there has been a subsequent lii.story after operation, and tlie patient has left the liospital. I find thirty-five cases have tliis histoi-y, ten of which are known to be alive. In these, the disease has lasted in one case, two months ; in one, one year ; in one, one year and a half; in five, two years; in one, two and a half years; in one, three years. Of which cases those numbered 24, 25, and 29 are now enjoying excellent health, the remaining seven are suffering more or less under the return of the complaint. Of the other fifteen cases, whose deaths are recorded with a history, in two, disease lasted one year ; in three, two years ; in one, twelve years ; in one, thirteen years ; in one, fourteen years ; or an average of three years and nine months for the fifteen cases. The furty-seven patients consist of twenty-three married women, fifteen single, and nine widows. After the operation, disease returned in nine cases of which there are histories. In these it showed itself in the space of time mentioned as follows :-— In No. 2 case, in three months ; in No. 10, in four months ; in No. 15, in four months ; in No. 22, in five months ; in No. 26, in six months ; in No. 27, in four months ; in No. 28, in one month ; in No. 71, in eighteen months; in No. 76, in one year ; or an average in the nine cases of four months. The youngest operated on was at 23 years of age, the eldest at 6S. More than half (twenty -six) were operated on for the first time at between 40 and 50 years of age. The age of the forty-seven cases averaged between 42 and 43 years at operation. The tenth case (Mrs. Jolly's) is a remarkable one. This patient had the left breast removed in Nov. 1875, the disease first having been noticed in 1872. She had eight subsequent operations for the removal of recurrences, and died in 1885, with the liver and other internal organs affected. (!ase 35 of the series shows an excellent result. Although there was an enormous mass of diseased glands and other tissue. Dr. MacCormick, the operator, determined to remove it, and finding it impossible to excise the mass without injuring the axillary vein, he ligatured it in two places, and cut out the piece between. There was no oedema of the arm, or other bad results from this procedure. I have no instances in this series of cases unoperated on — they have all undergone the operation — so that in comparing the duration of their life with those who have not been interfered with, I must fall back on my 1877 series. I find after reference to it, that there were five cases mentioned who died without operative interference. In these, cancer commenced while suckling ; out of these, one lasted one year, another six months ; while the other three lived respectively two, three, and nineteen years, giving an average of five years and two months to each. The average duration of life in those operated on in the present series, of whom we have a histoi-y, gives only three years and nine months, wliich is in favour of non-interference ; chose who were not operated on living eighteen months longer than those who were. There is no histoi-y recorded in these forty-seven cases of any person being cured by the operation. u 2 292 IXTERCOLOXIAL MEDICAL COXGRESS OF AUSTRALASIA. I think the majority of the profession will however agree with lue, as to the advantage to be gained in thoroughly following out Gross's plan, when excision is practised as a curative measure. The question will occur also, will you be justified in performing a palliative operation if you consider it impossible to remove the whole of the disease, and no ulceration is present 1 or if the patient be suckling, or the mamma inflamed? The answer, in my opinion, should be in the negative. After all, this operation is a very barbarous ])rocedure, similar to that practised 2000 years ago. May we not entertain the hope that one of our numerous distinguished pathologists may in the near future find a way to prevent the excessive formation of cancer cells, rather than to cut them away from the living body with a knife, as a woodman would a rotten limb of a tree with an axe ; or burn them with a red hot iron, as a labourer would a heap of rubbish in the corner of a back yard. Our hope must be in the future, not only by use of prophylactics to prevent its advent, but by properly constituted therapeutic measures expel the disease when present. Whether the excessive growth of the epithelial cells depends upon a microbe, bacillus, or other microscopic creature ; on the excess of white blood corpuscles in the system, or on some other morbid idiosyncrasy of the constitution, it is quite evident therapeutic measures are required to restrain the rapidity of their increase. "A cure for cancer " has been the usual cry of the quack during the generations ; but it should now be the hope, the wish, and the summit of ambition of practitioners of this age and hemisphere, to realise it by other methods than excision. In the meanwhile let us congratulate ourselves that at least one operator has had such successful results — I refer to Gross, of Philadelphia, who claims 30 per cent, of cures. He considers if the disease has not returned in three years, the patient is cured. My present series of forty-seven cases have twenty-five histories, and only one has lived three years without return ; of the other twenty-two cases, let us hope that many have been cured. According to Gross, who claims a cure when no return occurs after three years, there is only one in twenty -five cases. In my 1877 series of nineteen cases, the second case was operated on when the patient was 30, and there was no return at her death, at 65 — a perfect cure, the only one in fifteen operations. OBSERVATIONS ON SOME CASES OF CANCER OF THE BREAST. 293 ps i" 1. o 5 5 <« 1 o H < 3 ~ 3 £ l«! a ic a* ^ ^ S j5 M.j; >; Q Q •< .3 o 2 £ 1 .1 f 1 1 '■3 ,5 3 6 H s 1 o ■S ■^ to 5 5 •g § s 2 ■g 2, t3 " i S '? 2 .1 s •S si c" s U S ^ i. 5 i f 2 f 0'' 3 =1 -k^ 25 ^ % ? __ o o "ts o o cS "§ a ts S "3 rt c = >> = S-3 ., a 5 "3 _5 f _; -3 1 IZ .-5 ■3 f^ 1 -3 ^ 3< u 3 •3 -5 ^ 5 g "Z u 2 ^ il 2 3 b O 1 >. ^ "3 3 i 1 3 "rt ll 1 1 < o 1 2 f o 2 1 a 1.1 ^po •= 5 i ij ^ H kJ J ?; '-' K >J H ij ij •isasaaj iv aoy : ■: : : •HlVaa iV 30V ■o '^ 00 .Tt* I^ c-f = » ^t- r- O qIM 1-^ -■ ■i' ■HiVSQ JO aiVQ H cc ="2 O Z) I2 /^ 5=g ►^r-l <'^ *"* ■-S 1-H ? 2 8 Si J^^JO t z i: < : i? 2 '^ 'T '5 .-«" rii •2 S,2 s s > J-O ~ < "^ •asvssid 30 = 1 ^2 ."janiaa lo axvQ iz ^e »••= » 1- ■r> ?' 2^ 5 -^ _aoo -!5 ® "i ^ r- GO ■^ Xt '3 ^ *S 'n ^ CO % °° 1^. :: » a X cS 2 3co oi ^1 <5 2 ,3 . Si <2 " .■3 o* 2 ""^ ^ M "■'-' i'J i:- u: u ir is K CO — -o* -^ 7-J '-^ G^i iz. ^ * CO r^ T-* f-^ ffl -; ^ . M / cc ': M . U . • -A^ ^ ^ . *^- il > w ^. >1 ^•s Q>4 q:5 a-^ Om GO QO Q-1 o-< Q55 as aa •aanvaddv Jsai^ -•o _"0» 42 %r- j« aevasiQ kshav aiVQ 42 a2 S2 •aaavaadv .ishij c» to ■M o o C! ^ ^^ >^ uO asvasKi saHA aov U5 m •^ n o a -* ■* •* •v ■0 •Avoai^SV HO 1 ^ 1 _2 To J To -3 2 fe .s 2 s. "3) 'aiosig 'aaiaavjt r- .5 :- ^ S ;- 3 ^ .5 S " iZ a; ** ic J5 H ^ "^ s 'ji Cx .- °i --5 &<' S H U. ^ -J H ^ii B "p. d d u;' i_j < < ^;ft. ?. ^ =^ =^ <"■ S p5 H H =5 S i-j •3SV0 .10 OiJ -■ o so ■* us «o t^ 00 e» S "M 294 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. a ., r -^ i> 2 X u i u to ^ ■~ a_ !;• < .2 .5 o o S* >» £ tA CO u -c J o Q S 1 ':5 > ■l g ^ ■^ '"' c ■g "o i ^ ^ o ■g i ^ ♦^ a o < 1 03 1 S a 1 "3 f •2 o 1 S Q Q !5 1 > 1 c o- o CO 1 ■a 1! 1 "rt .. 1 E £ -y-j 5 rt a CO •S «■! C cS to '1*^ of 3 F 3 .3 ^ 3 9 "3 < i 1 C '^ as — i .2 -5 "S d 5 06 ;J 1 to < li g f _ a .3 ^ s - S. a' r S s tT 5 ^ Cl 3 fl i- 5 ■3 ■„" a 5 a_o c i 5^ K ^ rt r/2 9 "S " .H"^ .S -^ "S "^ Ij ~ -t % y - -' " C ^ ■-^ ^ "^ ■- •iNMsaHtl XV aov . CQ •Hivao; XV aoy o •* 1^ CO Tj* - -' — _" ■va ift ■ t^ "p t» >.l- _>>!- H.I.VMQ JO axvQ g-S gl 5 QO a » a ■» aj"-! S" l-J r-l I-: r- o =* , • C f- r o Z ^ f ^00 S, ^ ^ ^ a- z !r ■< ±; a; "£ 30 eS — >^ . y n ti — , a. 5 ^' ^ :; ^c S - §" o >-5 C/1 ^ _ •asvasid io fS. 2 00 Cot 1':^ "^00 NanxiiH JO 3XVQ <2 rt CO >-3 rH 1-5 i-l S CO f- >. >. S 1 z s R fc£ £ = a! '■'' .-= GO 2 ^ a CO 53 1^ ^ 00 = '>; c » 5^ If .2 CO CO •p d". _5 ^ 1^' "52 5^1 !£■= t- OT 2"^ co" 3 CO i-2 . c . > . >■ . sc >» ^ S > to' >; o Dm t. o £1 l.'~ t-^ =. C a. QS5 C^ c<; c-< p^; 0^ C^ Z o< •aaHvaadv xsaij ^ in a ^ o2 I55 asvasiQ NaH.tt axvQ <4i s « •aajivaddv xshijI c in o (N o CO C-. ry in CO e^ asvHsicT NHHAv aoy •^ ■* ■* ■^ IM M CO -<*♦ in ■* ^ •Moaij\v © .2 _« .2 D £ _2 •5 5 D J 5, MO To ^ Tc u To To 20 '? to t- To 'aaoNis 'uaiujivjt 5 = .= .5 .s ;- ^ .5 ri = V3 '* CO "* tc X (K ^ S X S i» S^ h3 si CJ ^ K r-i d ^ * o r^ s ?: d ■i "<■ • 1? < s d c: J e cd < <: J2Ch ^ ^ ^ ^ ^ ^ =s ^ d « d S ■asvo jio oi^ « ;; in o 1- cc Ol g S C4 CO ^ OBSERVATIONS ON SOME CASES OF CANCER OF THE BREAST. 295 . 2 rt .. >% !U .. .. ^ "o -g rt ca u _3 ai rt "3 < I C a a i 2 1 P >i4 Duration or Di 00 00 ■A s. 5 IE _5 CO a i a >> 1 2 £ 1 a, a 5. Is' >. '3 o 'A 3 o ~ ■i i a > rt .2 61 ° rt ;i • <3> H !" p. ^ ^ X! 1 H •< t 3 1 1 2 •- .2 ■" 3 S §■•2 1 1 s Q a 2" 5 ~ Q 3 ll 11 s S ^••^ 11 il a ll ■3 ... g 2 2 1 a 3 S . .SS: b U (K 'w ^ T* s i-« • - "* 2 ^ 'S '.3 t^ -^ ■ o .5 '^ S ~ |g a 1.2 s ,5 » ^ 2^ 1 S3 a: ^ ^ >> c 'S <: ^^o u ~. S t- s >» i. 2 -S2 ll ll 1 £ ~ 3 1 1 C3 .2I 1 - 3 <: K - 5 ^ Q Q B 5 ?^ •isasaaj iv aoy So CO -^ IN 5-1 •Hivaa iv aoy C5 s ••* '"' 00 ^ -0 >>-^ r-i p •HivaQ JO axvQ CD rH 02 s =0 ^2 i^'co 55 - ■ ^ z^ c j: "J3 •- X U g >i = « 00 ?.a' 6, z 2 < c < % ~ 53 53" t» f' 9^ •^ -^ K 5 - '^ 5j H -^O i ~ a c3 1^ 5 a — —1 — ►-5 — .*3 - •asvasiQ JO i-5>2 2'; S 30 — S saniaa jo a.iv(i 111^2 1-5 "^ 1-5 — H ^ i£i ■C M JS ■J y y « z » a '-' if 02 S QO o2 62 s . "I;?; c CO a *-^ fc 00 x> ^1 35t3 £iS2 a » a •-. J53 J; 00 pi* . to ^ 3 J- > u 2 lo 7: CO j^2 t; a. ^.^ c3 "l^ s 3 ;-• 3 Qfr; 0^ cS"! Q< Q^; o< a>? o< o4 (54 Q< •aaHvaddv xshij -■!,5 'ip 1- a o) Is ll Is g" ■•r Tf s-s ti asvasiQ KaHAv aivQ 5 " HO To "E '? tp _o 'r H _o _o To t: 'aioxis 'aaiaavK ,E ^ ^ X ;-■ rt j^ ;r &: .X jH M "^ ■^ m * S •^ '^ cc ''• < < o >J d d m d P3 ii ci d s S^d- J 1-5 < J i-s ^ W ai >-i •-5 •asvo ao -ovi ^ ? S^■; S S eo S3 ?s S g 296 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. . — » '^ IB < 2 1 i c 15 a S Si ■^ 1 Q o "2 o a fl S 1 o o ^ §■ a o oo 5 1*2 to a < <8 C3 CO a. CC a -a " ,s Q 1 s 1 o c — o "3 a 1 ' < S g a o C3 1 2 1 -i o p 1 14 j: ^ ^ s. d -a g .c ^ ^fH 2 1 ' J3 J35 a o & fl Q 1 a a a cr' g o a a 5 -e _« ? a ^ i X H o s "o §S o cr' 1 o o 1" ■2 o rt = S o 1: •< u a a s si s £ a ■2 s ! " -s . tS ce o ^^ s ^ >-t >. ;^ >> > X 5 ^> ■d h a g £" "3 > > » >■ 0.2 $ 55 ■e o p ♦3 ,-1 s £f § 1 o « -^?§ ■S"? J5 J3 ■3 = "p 2 "3 ■3 o1|^ •^-^ OJ Q a W H O o O O O Q O H •iNasaaj xv aoy in C5 lO 00 •* •HLvaQ iv aoy (M : : § OS a> '^oo •Hivaa ao axvQ * ^ Bt •g B go afe f^ 2^^ b, g 2 ->: o < en a: CC B 1^ S 6. <5 o 2| H MO t," rt ^« i= OS Ir^ 1^ Ift 00 lO CO lij to to 00 '-' oo i CO 1 00 Date of Operat By Wh Perfori o22 o 6- Is « i-H •§3 . Ml o ^ o Si «2 «2 PC p4 »2i ©►? t3 Ot» PO o< Q>5 QO o aevaBiQ xaH.tt aoy ■* e<5 lO ^ ■^ •A\oaiAV HO 1 1 -3 -o To s S To •c 1 To •2 ■5 'aiONis 'aaiauvjv s S s s t« ps c» S E= x s ^ C5 « a . 1 a !? ij w to a s m a < 1 ^ jzjfc o S S < ^ w « bli S s s g asvo JO "OX ^ S§ 05 •* 0-1 CO 5 S ^ 5; OBSERVATIONS ON SOME CASES OF CANCER OP THE BREAST. 297 > " _• i >« c^ o o ic «s VI g t^ O O O r-( 1 CO !B » .^ t- c; 'iiri 1 o •^ M Ji CO -^ M< -ti 115 >o U < < §• xa V. rh ai "^ a S A c 09 '.•? CO CO o ift »c CO i> CC O O O O ■^] o ira I'o CO »0 C5 CS -t* oo ^ CO lO 1(1 lO -* CO »o s a fe; < V ►< *♦* ►< g "1 Id «0 •** -S K o o b: o 00 !>• o X 00 >ft in t ^ . p 9 o o o p 00 ic M cb t?- eg -^ -ti C5 (N 00 S >- 5 lO CO '<}l M -* CO •>J< 2 S -S .9.3.S.S.S.S fl '"^6 pas "^ •2 5>> i« ,H i-H ,-1 —( r-( iH iH c O p 5 00 •> 00 ^ H r-H '^ K "S c :u ft ^ o o ^ a '^c:; P-, .T* ^ s a S g hCi ..'U c £ CO 00 r-l (N IN 00 t^ ,S ►<( e s 1-t tH C^ (N CO (M CO ^ fc -< r-l -Sv « s c g =>i a <^ S! ,^ s 05 ^5 a « -* (M lO o t- o o ,=*i Q 5 O O i-i oa lo o) CI ^ t- j « >« U rr C^ OC <-l X iM 00 of 'M c; .-H c; .-1 i-H CO '^ i-l T-l i-H 1-1 CO •^ g f2 ^ a O -^ IM CO ■* lO -3 < 00 CO 00 00 00 00 u: 00 00 00 00 00 00 -*^ !« r-l fH I-H i-H >-l i-H o H fin s ^ GO ~ O •" o -*■ o -^ C" CO ^ Ui rX) 2 ■«n r-l ^ r-t s ^ .o £ "^ 3 ^^ m •« e "5^^ T3 s ^ a -2 ^. ^ > Mg »« O t- 05 -H lO CTS CO t>. p o p 7< t-- t^ Cd C5 lio «5 CO 2x >ra CO i^ 00 cs x K 2 ?; z rH < < 73 m « :_ vo 00 n c~ -*< CO t^ a p CO p p p p P 'ji CO CO CO o A) f- r^ CO CO 00 C5 00 Cl X 2; ^ _fi i I-H ■< ■ji P H « a >: O M Z S5 -1 a Q > ^03 6 2 l£ - 2 ~ op t> CC CO >p C5 05 b: ^ an r^ cq oD tX) OS "* Ttl t^CO 00 ^ CO CO Q o .« >3 r. iH « < hS « J >^ 5 c « 2o o a: Ci, ^ X •5 a t^ t» t^ O -t -H CO 1 r~ * 1-1 I-l T-i iri ^ 01 O iH U 1 y. S ic 5g IM CO CO iC 00 O t~ CO 00 I-l ^ CO m M 1 og ^ O -^i 00 CO o X ' rH 1— 1 1— 1 ^H r-< C0 CO CO -^ — 1 "^ o CO O -f i-H T-l Lt l.-l 'c.'t '^ ■M iM "♦< -f -?> CI X ■ JM -< f- O H 1 s O <-! Cd CO "^ "5 1 00 00 00 X 00 00 c3 1 a X X » X X X H 1 ;- r-l 1-1 I-l I-l 1-1 iH W as «=" ss 2 fl -° a a> o 01 c3 "S cc o " o 3 (J) m 2 «= i "^ "3 '^ Ti c8 o 5 fci ^ o o S '^ a c w a> b< SO"" -a ^H to "" S a S ^•>; a ci a to >-. a ■s-« ! O g O a •« o 5 .2 S a a< -§.2 2 '3'S "^^ 04 a 298 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. ON THE USE OF SPECIAL EXERCISES, AND OF ACTIVE AND PASSIVE MOVEMENTS, AS AN AID TO SURGICAL TREATMENT. By R. E. Roth, M.R.C.S. Eng. M}' chief object in bringing the above subject before your notice is the hoi)e that it may help to supply a want felt among several of my colleagues who, when referiing to some of the various methods of treat- ment recommended in orthoptedic text-books, find certain systematic exercises (rubbing, &c.) recommended, but learn nothing as to the methods and manner in which such treatment is to be employed. Information also is very scanty as to the cases where such treatment by special exercises and movements is applicable and advantageous. Without doubt, the best and simplest scientifically-devised exercises, founded on sound physiological and anatomical principles, are those drawn up by Ling, and known as the Ling's or Swedish System of Gymnastics, where each individual exercise has been studied and con- structed with regard to its effect. The whole system is divided into four parts, to meet the requirements of educational, aesthetic, military, and medical |)ur))0ses. In the first, " exercises, with and without gymnastic apparatus," are made use of, and they are perfectly sufficient, when rationally applied, for the harmonious development of the body. The " cjesthetic " part is intended to teach the expression of ideas and sentiments by means of positions and movements, and is of great use for actors, orators, painters, sculptors, kc. The " military " is based on the pedagogic branch, to which are added sword, foil, and bayonet exercises, &c., necessaiy to the thorough training of the soldier. The "medical" or "movement cure" comprises special exercises devised for the treatment and cure of many chronic diseases and deformities ; it consists of active movements with or without assistance or resistance, of movements with special apparatus, and of passive movements usually grouped together as " manipulations." Active movements are all those which are executed by the special activity and determination of the moving person. They are always produced by the muscles subject to our will, and are the result of the organic contractility, influenced by our will. The special effects of a local active movement are — (1) To put into activity every single muscle, or oidy a i)art of it, or a group of muscles. (2) To increase locally the afllux of arterial blood ; and (3) to increase the innervation. Passive movements may be described as being executed either by living or inanimate agents, which are alone the moving power ; they are in no way connected with any special activity or determination of the person operated on. Among the special effects of local passive movements may be mentioned the following: — (1) the relief of pain; (2) moderate increase of the local nutrition ; (3) variations in the venous and lymphatic flow ; (4) restoration of the form, position, and direction of the parts, as well as the mobility of the articulations; (5) stimulation J INSTRUMENT FOU REOOHDINfJ LATERAL CURVATURE OF SPINE. 299 of the innervation in tl)e sensory fibi-es ; and (6) to increase or diminish the teni[)erature of the body, or a part of it. ^Movements are natural curative agents in many diseases. Voluntary or involuntary, active or passive, tliey act in a most extensive manner, by preventing, allaying, curing, and suppressing disease. They eflect their purpose either as derivative from the sensitive nervous parts, or as neutralising the bad effects of external injuries. In the healthy state, the brain expresses its sensations and ideas by muscular action ; in disease, it does the same. During pain, or any other disagreeable sensation, it is the commonest tiling in the world to see the sufferer either making a grimace, twisting his trunk, moving his limbs, or rubbing the part. Patients in delirium or mania often find relief by screaming, shouting, and other violent movements. On the other hand, we often see the sufferers relieved by voluntarily suspending muscular action, by resting the body, or part of it, in this or that ])osition ; for instance, we might contrast the elevation of an inflamed limb with the prone position of a fevei' patient, or with the stoojiing position of an asthmatic martyr. Active movements are used therapeutically, in order — To strengthen and fortify a muscle — that is, to form new and stronger muscular fibres ; to effect a better innervation of the motor nerves ; to increase the temperature ; to promote the formation of arterial Ijlood in general ; to derive blood, principally the arterial, from neighbouring organs ; to effect an increased circuhition of venous blood and Ijniijjh fluid, not only in the muscles, but also in more distant regions of the body ; to relieve the contraction of certain muscles by strengthening their antagonists. Passive movements are used therapeutically — In hypertroj)liy, due to congestion ; for the removal of the products of inflammation ; in dilatation of the veins ; in disorders of the valves of the heart ; for the relief of pain. [A number of cases were here related by the writer.] AX INSTRUMENT FOR ACCURATELY RECORDING LATERAL CURVATURE OF THE 8PINE. By R. E. Roth, M.R.C.S. Eng. This little instrument, which I have the pleasure of bringing before your notice, I invented some time ago, in order that I might accurately record from time to time, in my case-book, the improvement that took place in scoliotic patients, who were undergoing a rational gymnastic treatment. The usual method of i)hotographing, or making a sketch of a scoliotic before and after tieatment, is always unsatisfactory, because it is so easy to minimise or enlarge the cuives according to will. I take advantage of the fact, that rotation invariably accompanies lateral curvature, so that if we make a tracing, showing the differences of the back on both sides of the spinal column, we have an accurate record of the extent of the deformity. But this tiacing must l)e made under certain conditions, otherwise we are liable to error. The patient having had her clothing removed, and fastened around the hips, just below the 300 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. trochanter, the surgeon stands ])ehind, and corrects any irregiilarity of the hips by placing a suitable block, or a small book, under the foot; he then requests the patient to stoop forward, and to allow the hands to hang as much as possible. By this method, all weight is taken off the spinal column, and any curvature and rotation that is now noticed will be of a permanent character, and cannot be either increased or diminished, so long as the patient is in this ])osition. In order to make a tracing, 1 place the stand of the instrument at some chosen sj)Ot on the spinal column, the chosen sjjot being the length of the long arm of the lever from the ijart which we wish to trace. Now, on holding the stand firmly down with the index and middle fingers of the left hand, and on slowly moving the ivory point at the end of the lever with the right, the short arm, which carries a pencil, makes a correct tracing on the slip of pa])er, held firm by a curved piece of tin. The resulting tracing, which is reversed in size, will depend on the ratio of the short to the long arm of the lever ; in this instrument, the tracing made is one-fourth of the natural size. CASE OF COMPOUND DISLOCATION OF ANKLE JOINT, WITH FRACTURE OF ASTRAGALUS PER ;SE, AND RESECTION OF SAME. By H. C. Garde, F.R.C.S. Surgeon to the Maryborough Hospital, Queensland. The notes of the case which I now bring before you were taken some years back, but as the injury to the astragalus is of a rather exce[)tional nature, they may not be deemed unworthy of reproducing. On the 11th March, 1882, Robert P., aged 33 years, fell down the hold of a steamer (some twelve feet) landing on his feet, and which he said immediately turned under him. I .saw him on the wharf, half an hour after the accident, and found him suffering from a Pott's fracture of the right foot, which was readily brought into position. On cutting off the left OPERATION FOR DILATATION OF PYLORIC OIUFICK OF STOMACH. 301 boot a more serious state of affairs presented itself, viz., a laceration of about an inch in lengtli on the inner side of the foot, through which a fractured surface of bone protruded. My colleague, the late Dr. J . J. Power, just then arriving on the scene, we decided to i-eniove the patient to his own house before doing anything further. On arriving there chloroform was administered, with the double view of relieving pain and facilitating the reduction of the dislocated and fractured bone. On careful examination, we found we had to deal with a portion of the astragalus, which was dislocated inwards, forwards, and u})wards. Every means, including enlargement of the wound, and division of the tendo Achillis, was tried to re]ilaee the bone, but without success ; so that nothing remained to be done, but either to amputate, or resect. We decided on the latter, which I accordingly did, removing the body and portion of the neck, the greater part of the head of the bone remaining in situ. The anterior and external portion of the posterior facet on the inferior surface was also fractured, and as it could not be got at readily, was allowed to lemain. The foot was then brought into position, and kept on a back splint. Listerism was not carried out, but the strictest cleanliness was observed, with the result that the wound healed in six weeks. It took a few months before he was able to get about, but since then lie has continued at his work (wharf storeman), and can walk without a stick, but has a hardly perceptible lini]). The chief point of interest about the case is the fact that neithei- of the other bones forming the joint were injured, and it is difficult to account for, how such a strong bone as the astragalus should Ije smashed right across, and the greater portion of the bone shot out of its place without more or less injury to the other bones whicli articulate with it. [Dr. Garde exhibited the specimen, which is a most interesting one.] A CASE OF LORETA'8 OPERATION FOR DILATATION OF THE PYLORIC ORIFICE OF THE STOMACH. By Wm. Gardner, M.D., CM. Glas. Lecturer on Surgery, Adelaide University. Senior Surgeon to Adelaide Hospital. The following case is recorded, not because I deem it to be of any value as an isolated instance of success, but because it is the first pub- lished example in the Australian colonies of a procedure highly recommended in similar conditions by Professor Loreta, of Bologna, who performed his first operation in September 1882. A full account of this was published in the British Medical Journal, Feb. 21st, 1885, by Mr. Holmes. On April 2Gth, 1884, a short account of Professor Loreta's ninth ojjeration, which was for contraction of the cardiac orifice, is given. The operation has also been practised by a few other Italian surgeons, and in two cases by INIcBurney, of New York, notes of whicli are to be found in the Nev York Medical Journal, of Jan. 16, 1886. So far as I know, the remote results of these operations have not yet been publislied, and the value of the operation is still sidj judice. The immediate results of the published cases have been excellent The operation is suitable for cases of simple cicatricial or fibrous narrowing of the pylorus, or the cardia or lower end of the ccsophagus. The 302 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. narrowing iu simple cases is due to Ijypertrophy of the involuntary muscular fibre, and over-distension of this is the object to be aimed at, and the result is said to be as good as in cases of over-distension for tibrous stricture of the rectum. Reasoning from analogy, every surgeon would be disposed to say that the good result will only be a temporaiy one, as is certainly the case iu all true strictures of the urethra. This is the great point which has yet to be settled, and I offer ray tirst case as an encouragement to others to perform the operation, and note carefully the immediate and also the remote result. In this way, and in this way only, can the permanent value of the procedure be estimated. The patient upon whom 1 operated was sent to me by my friend Dr. Baly, of Yorketown, with a note, stating that she had long suffered from pyloric obstruction, and that he considered the case a suitable one for trying Loreta's operation. Every form of treatment had been tried by him for months, and after consultation with my colleagues, I determined to make the attempt, and as the evident thickening of the pylorus might turn out to be malignant, I made every preparation for performing })ylorectoniy, should it be deemed necessary. For the same reason, I made use of a transverse incision, such as Billroth recommends for pylorectomy, and I found this quite convenient for the other operation. The following is tlie case : — J. H., aged 43, admitted to Adelaide Hospital July 15, 18S8. History. — Patient complains of sickness, and pains in the region of her stomach. When she takes anything, it usually lies on her stomach, and makes her feel very sick. She has been troubled with indigestion, off and on, for several years, but during the last tln-ee months it has got very much worse, and ])atient finds her strength failing. As a rule, she vomits e\'ery other day, and generally in the evening. Sometimes, however, she goes for four or live days without being sick, and then vomits up over a chamberful. The pains across the upper part of her abdomen are of a shooting character, and made their appearance about three months ago. They are very much worse just before vomiting, on account of the distension of the stomach with gas, which has then occurred. The pains increase in proportion to the amount of flatulence present. Previous health has been good, as is also the family history. Has been married twenty-four yeai's, and has had nine children, the youngest of which is Ave years old. Climactery three years ago. r resent Condition. — The stomach is of variable size, but distinctly enlai'ged, and on some days its outline can be traced on the abdominal walls. To the right of the median line, and just above the umbilicus, may be felt a lump aboitt the size of a walnut, which moves up and down with the movements of re.spiration. The vomited matter is of a yeasty cliai'acter, very acid, and contains sarcinsTe in abundance. Urine is acid, and contains neither sugar or albumen. Professor Rennie kindly examined the vomited matters, and reports just a trace of free hydrochloric acid. July 19th. — Comi)lains of a boring pain in her stomach. July 26th. — Patient anaisthetised, and stomach washed out with two pints of weak boracic lotion. July 30th. — Patient anaesthetised, and stomach washed out with five pints of the lotion. The tumour could be felt readily on eacli of these occasions. OPERATION FOR DILATATION OK PYLORIC ORIFICE OF STOMACH. 303 Aug. -ith.— Patient hcis been on milk diet, and lias not been sick since first washed out. To liave milk, baked a|)])les, etc. Aug. 6tli. — Patient sick this evening and last niglit. Aug. 7th. — Patient vomited again this evening. Aug. 11th. — Patient partially ansesthetised, and stomach washed out. The Operation. — On the V2t\\ August, 1888, the patient having been placed under the influence of ether, Dr. Gardner pei'formed the following operation : — (The stomach was thoi-onghly washed out with a boric acid solution). A transverse incision, about four inches long, was made in the e})igastric region, and the skin, muscles, and fascia, down to the peritoneum, were rajjidly divided. All bleeding points were ligatured with wallal)y tendons, and the api)lication of hot sponges for a few minutes effectually stoi)ped the oozing, before the peritoneum was opened. Although no tumour could be recognised in the neighbourhood of the pylorus, the walls of that part of the stomach were very hard, and greatly thickened. A portion of the viscus was then drawn out through the opening in the abdominal parietes without ditticulty, as no adhesions were pi-esent. After the extruded part had been carefully surrounded with hot sponges, an opening one inch long, running in the long axis of the organ, was made with scissors, through which the operator inserted the forefinger of his right hand. On examining the pyloric orifice, he found it almost completely closed, and it was with some difficulty that a No. 6 gum elastic male catheter was made to pass through it. After patiently boring with the right forefinger, the passage was gradually opened up, the forefinger eventually being passed with ease from the stomach into the duodenum. The hasmorrhage was very slight indeed, and the interior of the stomach having been cleansed immediately before the operation, no difficulty was experienced with the stomach contents. The wound in the gastric wall was brought togetlier with great accuracy, and in a most satisfactory manner, by means of Gussenbauer's sutures, which were introduced with sjjecially curved needles, and an interval of about two millimetres allowed between each. Fine silk was employed. All the stitches were [)laced in position before any were tied. The wound in abdominal wall closed in the usual manner. Aug. 12th, evening. — Patient complaining of ])ain since the operation. No vomiting. Enemata of milk, ?ijss, and brandy, ^ ss, every eight hours. Enemata of port wine every eight hours, J iij. R. Strychninaj, gr. 4; glycerine, 3 ij ; aquam ad., Jij. Fifteen drops (J^ gr.) hypo- dermically every four hours. Aug. 13th. — Patient slept very little during the night. Wind troublesome. Passed urine at 2 a.m., lOi ozs. Temperature, 100° ; pulse, 125. Enema of soap and water. No vomiting. Aug. 14th. — Patient slept well during the night. Passed flatus i)er rectum, and found great relief. No vomiting. Aug. 15th. — Bowels not open ; has passed flatus. Thei-e is no abdom- inal distension, but complains still of flatulence. There is some pain in her stomach. Aug. 16th. — Very restless during the night; still complains of flatulence. No vomiting. Gruel, a teaspoonful every two hours. Aug. 17th. — Slept very little during night; still passing flatus per rectum, causing pain. No vomiting after giving gruel. One stitcli 304 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. removed. 6.15 p.m. — Patient comfortable. Supp. morph. gr. \; mitte iij, one every six hours. Eiiemata of brandy and milk. Aug. 18 til. — Complains of very little pain ; still much flatus passing per rectum. Bowels moved at 3.30 p.m. No vomiting. One teaspoon- ful of scraped rump steak every four hours. Give ten drops of ac. hydro- chlor. dil. quarter of an hour before, and then gr. iij of pepsin immediately after. A teaspoonful of milk, and two teaspoonfuls of lime water, every four hours, alternately with the beef. Enemata of milk every four hours. Injection of strychnina, twice daily, gr. -gL. Aug. 19th. — Wounds dressed. A little discharge. .Stitches removed. Aug. 20th. — Wound dressed. Looking well. There is a little inflanniiatory hardening about the wound. Enema of soap and water, and bowels moved well. Aug. 21st. — Omit raw meat. Give chops and fish instead, and also bread and biitter. Enemata every six hours only. Aug. 22nd. — -No vomiting. Comphiins of pain in her right side. Aug. 21th. — There is a little discharge from the centre of the wound. R. Liq. strych. m. iij, aq. ad. 3j, thrice daily before food. Aug. 28th. — The edges of wound are uniting fairly well. The skin is a little inverted at the edge. Still inflammatory hardening about the wound. Aug. 29th. — Patient complains of pain in her stomach. No vomiting. Food does not cause her trouble. Aug. 30th. — Still has crtirapy pains in her stomach at night ; relieved last night by some warm water and brandy. Scarcely any discharge from the wounds. Sept. 7th. — Patient says that she feels fine ; never feels sick, but nearly every night she has pains of a burning character about her stomach. She eats bread and butter, eggs, toast, cake, mutton, beef, custard, and drinks milk and cocoa. She does not take pudding, vegetables, or tea. The temperature I'ose above 100" on only one occasion. For the short notes of the case, I am indebted to my dresser, Mr. Verco ; and the account of the opei'ation was written for me b}'- Dr. Giles, who assi.sted. On Dec. 24:th, 1888, Dr. Baly, at my I'equest, kindly sent me the following note, after examining the patient : — " Patient looks and feels perfectly well, and has evidently gained flesh in a marked degree; weight 7st 101b (weight l)efore operation not known, but Mrs. Hewton thinks she must have gained a stone). Has never vomited since the operation, and has had no ])ain since leaving the hospital. Is able to eat ordinaiy diet without inconvenience, but has felt somewhat uneasy aftei' eating beef, cabbage, or rich cake. Can eat mutton, poultry, fish, and farinaceous puddings, and drinks tea three or four times a week. No flatulence, heartburn, or eructations now after food ; bowels regular. Ate green peas several times during the season without any bad effects. Examination : — Abdomen well covered (instead of appearing a mere envelope of skin, as it did before operation) ; skin over site of operation freely movable ; some induration still to be felt in the region of the ])ylorus. Gastric resonance not increased upwards, or to the left." He adds, "you will recollect, of course, that before the operation, even a little milk used to cause Mrs. H. great agony." THE SURGERY OF THE KIDXEY. 305 I have quoted Dr. Baly's words, although not intended l)y him for publication, as I am anxious not to interpolate in this account any bias of my own in favour of tlie operation. In conclusion, I must say that in my opinion this case warrants me in recommending those of you, who have the chance, to give the operation a fair trial, and publish your resiilts both immediate and remote, for only in this way can we arrive at a satisfactory conclusion. THE SURGERY OF THE KIDNEY. By William Gardner, M.D., CM. Glas. Lecturer on Surgery, Adelaide University. Senior Surgeon to Adelaide Hospital. The surgery of the kidney is one of the greatest developments of modern surgery, and dates from 1869, when Simon, of Heidelberg, l)erformed extirpation of the kidney with the object of curing a urinary fistula. The case was a complete success, and six months after, the patient was in perfect health. In 1690, Blancard suggested that extirpation of the kidney might be attended with a successful result in cases of renal calculus. In the earlier part of this century, the kidney was several times i-emoved successfully in animals, and accidentally in man, by Wolcott (1861), Spiegelberg (1867), Peaslee (1868), and Spencer Wells. In 1870, Thomas Smith, Surgeon to St. Bartholomew's Hospital, wrote an article in the '• Medico-Chirurgical Transactions," recommending nephrotomy as a means of treating renal calculus ; and this operation was performed, for other conditions, successfully in 1870 by Durham, Moses, Gunn, and Bryant. Nephro- lithotomy was first performed by Mr. Henry Morris in 1880. Nephrorraphy was first performed by Professor Hahn, of Berlin, in 1881, and since then he has repeated the operation several times, and always with success. My own operations on the kidney began with a case of nephrotomy for scrofulous abscess, performed on May 16th, 1883, in the Adelaide Hospital ; and although the patient only lived a month afterwards, he experienced great relief, but eventually died of ui'temic convulsions. At the post-mortem, it was found that botli kidneys were diseased, the right (the one operated on) being in a more advanced stage of disease than the left. Nephrectomy was first performed by me in October 1885, upon a patient who, in February 1884, had an abscess of the right kidney oi)ened and drained by nephrotomy. The operation was necessitated by the persistence of a urinary fistula in the right loin. Langenbuch's abdominal incision was used to ascertain the state of the other kidney, and as it was found not greatly enlarged, the right kidney was removed by a lumbar incision, and the abdominal wound closed in the ordinary way. Suppression of urine caused death in forty-eight hours ; and at the post-mortem there were no signs of peritonitis, but the left kidney was found to be in a state of fatty degeneration. On Dec. i, 1884, I operated on a case of movable kidney, which had given rise to troublesome symptoms, fixing the kidney to the sides of the lumbar incision by two kangaroo tendons passed through the substance of the kidney. The result was completely successful, and she has remained in splendid health, and free from all her previous troubles to date. Nephro-lithotomy was first perfoi-med by me on Feb. 10th, 1887, X 306 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. for calculus, and in a fortniglit the patient returned to his home, and in a short time was able to resume his work as a lumper on the wharf ; and a few days ago, I learnt from his father that he had never had a day's illness since. Appended to this paper is a tahle of all the operations on the kidney which I have performed, and also detailed accounts of several of the }nore interesting cases. They include three cases of nephro-lithotomy for renal calculi; No. 7, in which a stone weighing twenty-five grains was removed from a healthy kidney. The patient had been suffering severely for three years, and within a month was able to return to his work as a lumper on the wharf. No. 13 was operated upon by Terrier's transperitoneal method, because the kidney was enlarged and contained fluid. The cause was not diagnosed until the kidney was incised, and then a small fragment of calculous matter was accidentally felt and removed from the inner wall. A further search led to the opening up of a calyx, and the removal of an irregularly-shaped calculus, weighing ninety-six grains, from which the former had become detached, the line of fracture being distinct, and the fragment afterwards fitted on accu- rately. In this case, the sacculated kidney was not removed, but drained by a glass drainage-tube, and the result was perfect, the wound healing up without leaving any fistula. No. 14 was diagnosed as a case of stone in the right kidney, and at the operation the organ was found so irretrievably damaged, that it was removed by nephrectomy ; and this course of action was taken because pyo-nephi'osis was found. We have thus examples of three different conditions : — • (1) A calculus removed from a sound kidney, with preservation of the organ, and without the formation of a urinary fistula. (2) Removal of a calculus from a hydro-nephrotic kidney, with retention of the damaged organ, and cure Avithout the formation of a urinary fistula. (3) Removal of a calculus from the kidney, which was irretrievably damaged and contained pus, and was, therefore, removed at the same time. The first case is undoxibtedly the best, as the healthy organ was retained, and when contrasted with the others, shows the immense advantage of an early operation. On the other hand, there is an advantage in diminished risk in operating on cases complicated by hydro- or pyo-nephrosis, because the other kidney, during the process of destruction of the one, has been gradually educated up to do extra duty ; and so the risk of suppression of urine is lessened, much in the same way that gangrene is less frequent after ligature of the femoral for aneurism, when pressure has previously been tried, than when it has been performed without such previous treatment. The cases also show that the remains of the kidney may be left behind when the coiitents are serous, but that it is probably the best practice to remove the damaged organ when pyo-nephrosis is present. Nos. 4 and 9 in the table exhibit the great advantages to be derived from nephrorraphy in suitable cases. Both cases were absolutely restored to liealth. In conclusion, let me say that I have not ventured on the debatable ground of diagnosis, but have endeavoured to lay before you, as shortly as ])Ossible, my own work ; and I trust that it will be found not to be without some interest to the members of this Congress. TUB SUUGEKY OF TIIK KIDNEY. 307 .£ =3 g Cl! to c ■§■ 1 ober 6th, as he was losiug liual iucisioji haviug first 3ath occurred iu 48 lioiirs, pust-morteiu, iu the left 2 60 ii ■§'2 i^ 5 3 --^ 5 60 111 %% a - Ii a2 .2 ^ ■3 3 3 60 a — !a "3 aB to ci rt _r . °^ 'S = B u i a >> 5 — J- to _!.2 « 5 '"is 2~ a g £3 M > 3 P •5 2-^ ^1 Si "T, — a ii 2-2 T a 5 — ' 15-2 rt to ^ ■*^ s 60 5>i| to "5 5-3 _5 S 60 i:S 2 a o •3 S >i 5"!! s a^ %l a"" '2 ■^ 3 s -a -n rt w a2 p _s -- > a* 2t3 60^ 5 III ■S3 S 0) dj rt o5 rt a« £ J.-|6p £■5 • •= ° 8 o-a t- IP ^^ ^. g yj <„ =« 2 ■3 g-a a'" > c -'2 .2^ 60 2-^5 111 5 s a 60 a. B 3 " ^ 2 60 5 5^ "2 Pi -« P. 03 |i 1'' 11 IS »-* CO ^• -^ n — ' S o 13 2 • ""^•^ 5 ° •-1 >> «l s 5- O '^ 55"" C 60 CO Sols fiil ^ a 5= S ^ 5 >>'" 9 5 2 5 O so Ij » S >>-S =^ 2 S-s'3 -^ £ m 3 itil rt s a s = « 2 S ° 3 " "> Ii g 'I -n a lit III s ■»^ a o - S "3 2 s Sort pi ^ a? O 60 ^ S Em •= i o -■ ? !* 2 3 9 '?■§ 60 - %% %\ If as s s |i o s = "5 . "^•S a 2 > o 111 s a t3 ^1 i a >'^ 3.'' '" £ -r"S i^oSg " '^ to = S?2 g ci 2 =«" 60 5:5.2 5 _a . ill CO a* 5 ® ^ til s a-^ a==2 .2 >;2 lll S'S 2 22« ~3^ 2 2^ -1 ? "3. 3 -S ° M a a ■^ "S 28 60-:; p a rt '^ tl ^5 &•! a 5 i3 3 2 m" a^2| S fa 1 3 0-;= S^ a » +i - - Ja^^ ^ w 53 te i|a§ S _e a a C3 a a a ° i '^ [5)|_3 2I2 S a c« 60 a ■.'■^■^ a ^ '■" .2 5 "S ■3 ^ -2 PI 5 2 cl 1% 2 ^ 11 5 o ^ fc- fa H ^ ■< H "^ hi fa H « -^ "5 > y to ^ g a ^ ';^ *:2 3 2 S5 ^ 13 ^^ ^ - o a b O ■a o s 3 >. 5 >i 1 _S >> 3 II >= 1 2 "5 p "^ ? P ■43 6 ci ^ cS a « (n k; >i ^ *^ ^ S^ ^ >-! ^ y^ < < ^ ^ < a = IS 5 1 >> 12 ? 2 12 _o 13 a. > 5 1 t p ,a 2 - ^ p = "5 ;| 5 ~ C - 3 -J a - 3 c a. "^ p c -J % g P o p > "c a o ^ rj 3 "a "cS ;^ £-a t-l >>3 ^ 39 xn 03 s m H S !» H a K 6 1 at u,--= ^ o ' r- "-^ ^^- 00 '-' -0 1^ '"' 00 ^ O) CO i-s " o' '^ s CO ^• ?° X CO . CO to "g si 2I g±> S ":2 "o "p rt Z> '"fa r-< ^^ ^C r-« ^ J y • ^^. a a «— ' ■i ■J. <"' r^ ,f. '_^ t::^ X ►^ _^ * • 10 y^ li "-5 ■^ ■^ ^- ^ ^ ~' - =^ d ^ ^ ^ s ■c o r-l •M SO •* m •.0 f- 00 ^ ^j CO ^ " *"* *"* i-H *"* X 2 308 intercolonial medical coxfjkkss of at^stralasia. Treatment of Kidney Disease. Case I. John Smith, a^t. 28, seaman ; tuberculosis of kidneys, nephrotomy, death. April 13, 1883. — Aspirated in right renal region by Dr. A^erco, and two ounces of fuetid pus drawn oft'. May 5. — Transferred to surgical wards under Dr. Gardner's care. May 16. — Has a high evening temperature ; passes three pints urine in twenty-four hours, M'hich contains pus. At 4 p.m., under ether, and using the carbolic spray, Dr. Gardner made an incision down and into the right kidney, evacuating from six to eight ounces fnetid pus. The kidney was freely explored by the finger; no stone found. A large tube inserted, and gauze dressing applied. May 17. — Temperature normal ; feels better, and .sits up in l^ed with ease ; moves more freely than before operation ; on dressing, ^ery little dischai'ge found. May 18. — Dressed; urine dai-k olive colour, and contains albumen. May 20. — Dressed ; discharge oozing tlirough l:)andages ; some pus in urine ; bowels confined. May 21. — Temperature rising every night ; urine over three pints, ' no pus ; feels well. May 25. — Dressed ; gut sutures dissoh ing ; tube removed ; urine clear, four pints per diem. June 11. — Discharge increasing the last week; patient much weaker, and at times delirious ; urine clear ; bowels rather loose ; takes nourish- ment well ; an epileptiform attack to-day. June 16. — Urine ruby red colour; contains blood. June 17. — Worse; passes evacuations involuntarily. June 18. — Two " fits" last night, one this morning. June 19. — Died, having had sevei'al more "fits." On post-mortem examination, both kidneys were found to be scrofulous, and have been exhibited to tlie Society. Cases II. and III. Alexander M'Leod, pet. 42, gaoler ; abscess of kidney, nephrotomy, recovery. January 21, 1884. — Five years ago, experienced a scalding sensation on passing urine, and this continued for about six months, when it was so bad as to necessitate micturition every hour ; medical treatment for six months, without much benefit. For two years svibsequently had scalding, but not such frequent micturition. Two and a half years ago jiassed Ijlood with the urine, and had, at intervals of about a month, colic attended l)y \oniiting, and pain in the hypogastric region. This lasted about two montlis. Has since been pretty well, until witliin two months ago, when pain set in in the right lumljar region. No scalding for about twelve montlis ; apparent fulness of right lumbar region, with dulness on percussion in front; no kidney mai'gin to be made out; complains of pain on manipulation in both lumbar regions, but especially the right. January 22. — Uiine slighty acid and copious ; contains phosphates, and nuicli pus. THE SURr.ERY OF THE KIDNEY. 309 January 24. — Gets up once every night to micturate, and passes water three times during the day ; has occasional lumbar pain passing down the right thigh. January 26. — Urine deposits less ; no albumen ; slight trace of phosphates. January 28. — Dulness of riglit back, with absence of vocal resonance and vocal fremitus ; pleurisy with effusion. Transferred to Dr. Yerco's care. February 24. — Sent back from medical wards, fluid having become absorbed under ti-eatment. February 29. — Under ether, and using a carbolic spi*ay, an incision was made into the kidney, and one and a half pints of tliin pus evacuated. Marcli 1. — Dressed ; very little discharge. March 5. — Dressed ; less discharge. Two weeks after leaving the hospital, the patient returned to his duties as gaolei', and was able to continue his work to the end of April 1885, when he began to lose flesh, and on the 18th May was re-admitted into the Adelaide Hospital. He has lost five pounds in weight during the last month. There is still a sinus in the loin, from which pus escapes, and a probe can be passed along it to the depth of three inches. The urine is acid, slightly turbid, and contains no albumen. The average daily amount for a week was 50 ozs. June -t. — Professor Rennie kindly estimated foi- me the quantity of urea daily excreted, and found it to be 400 grains. June 5. — After a consultation with my colleagues, I determined to attempt removal of the kidney, a procedure which was rendered neces- sary by the downwai"d tendency of the case. The patient having been put under the influence of etlier, I made an incision obliquely from the twelfth rib to the crest of the ilium in the right lumbar region, keeping as nearly as possible in the line of the old cicatrix. Tlie edges of the wound being held aside by retractors, I continued to cut down to a depth of three inches, and on thrusting in my finger, I felt three openings lead- ing out laterally, which appeared to be tlie calyces of a dilated pelvis. I then came to the conclusion that the kidney was so incorporated with the surrounding structures, that it could not possibly be removed. A large drainage tube was inserted, and the wound closed with metallic sutui^es. The subsequent progi-ess of the case was uniformly favourable, thei'e being no rise of temperature at any time, and the patient was dis- charged on the 28th July in niucli tlie same condition as when admitted to tlie wards. October 3. — Patient came to my consulting rooms, and besought me to do something for him to relieve his present condition, as he felt himself sinking gradually. He elected to enter a private hospital, and I determined to make another attempt to remove the kidney. October 6. — Assisted by Dr. Giles, Dr. Moore giving ether, I made an incision to the outer side of the right rectus (Langenbuch's) four inches long, and divided the tissues down to the peritoneum, which I carefully opened, and divided to the full extent of the external incision. I then gently passed my hand into tlie abdominal cavity, and felt the right kidney considerably enlarged, but still movable, and therefore not, as I had imagined, incorporated with the surrounding tissues. Passing 310 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. my hand cautiously across to the other side, I examined tlie left kidney, and it felt to me about the usual size. I then determined to remove the right kidney through the lumbar incisions, if possible. Napkins dipped in warm carbolic lotion were laid over the abdominal wound, which was kept thoroughly closed by Dr. Giles. I then cut down in the lumbar region through my previous incision, until I felt the kidney, which was very much enlarged, but freely movable. As there was not room to pass in my whole hand, I made an incision along the whole length of the twelfth rib on the right side, separated the peritoneum, divided the rib with the bone forceps at its spinal end, and removed it. I then easily introduced my hand, and grasped the kidney, which was extremely brittle, and dilated to a shell. A great deal of the kidney structure broke down under the finger, but by gently pulling, I was enabled to get the pedicle so far out as to transfix with a double ligature, and tie in two portions. The cavity was then washed out with tepid water, and the peritoneum found to be intact, as the water soon began to overflow. A large drainage tube was inserted, and the wound brouffht toijether with metallic sutures. The abdominal wound was now closed with silk sutures. Lister's antiseptic dressing was employed. The whole operation lasted one hour and a half. On the morning of the operation, the temperatui'e stood at 100"4° F., and immediately after the operation, it fell to normal, and continued so during the further progress of the case. October 7. — Slight vomiting thi-ough the night ; profuse perspirations ; passed seven ounces of high-coloui'ed urine. At 10 a.m. the wound was dressed. Beef tea and brandy enemata were ordered every two hours. No sickness during the afternoon. Slept at intervals. At 6.30 p.m. patient became very restless, and vomited. The catheter was passed twice during the day, but no urine was found in the bladder. October 8th. — No urine passed, and vomiting continued at intervals until death, which took place at 2.30 p.m. Post-mortem Examination. — Body much emaciated, skin jaundiced, abdomen distended. In the anterior abdominal wall, three inches to the right of the linea alba, is a longitudinal wound brought together with silk sutures. The skin in the neighbourhood of the wound is somewhat dark and discoloured. Over the right kidney, in the lumbar region, is a wound extending from a point just above the twelfth rib, downwards for nearly six inches. Running from this, in the direction of tlie I'ib, is another incision, about four inches long. Through this, tlu'ee inches of the twelfth rib liave been removed. On opening the abdomen, some flakes of lymph were observed on the intestines. One recent adhesion exists between the wound and the ascending colon ; and between the lower lobe of the li^•er and tlie intestines adjoining, are several bands, also quite recent. Very extensive old fibrous adhesions are found between the ascending colon and the posterior al^dominal wall. The abdominal cavity contains about six ounces of thin watery fluid. The inner surface of the wound in the anterior wall looks healtljy, but all the sutures have torn tlirough the peritoneum, and a gap of nearly one inch is seen between the divided portions, showing some tension has existed. The intestines are enormously distended, but not matted togetlier, and appear quite healthy. No trace of tubercle in any of the mesenteric glands. Right kidney THE SUUOERY OF THE KIDNEY. 311 absent. A large cavity capable of admitting a man's two fists, enclosed by thick fibrous walls, and completely shut oft' from the peritoneal sac, communicates witli the wound in the right lumbar region. It contains a few pieces of broken down kidney substance, and small blood clots. The pedicle of the kidney is also found here, firmly tied with a double silk ligature. Left kidney is enlarged, pale, soft and flabby ; the capsule readily strips oft"; the cortex is somewhat wasted and yellow. Distinct signs of fatty degeneration are present in this organ. The right ureter is embedded throughout its entire length in dense hard fibrous tissues, forming a thick band which is firmly adherent to the underlying muscles. A probe passes down it with ease. There is no trace of dilatation. The left ureter is normal. The bladder is small and contracted. About a teaspoonful of thick pus escapes on opening. The walls are a quarter of an inch in thickness. The mucous membi-ane is corrugated and hypertrophied. The prostate appears healthy, normal in size, and shows no sign of any tubercle. A Case of Nepltroto^ny. January 22, 1884. — Mrs. N. consulted me; manned twelve years; two children living ; nine have died ; the children living are the fifth and the first ; took ill three years ago after confinement ; micturition became painful, and white sand came away in large quantities ; the urine became turbid and smelt badly ; pain began in the right lumbar region, and passing across the abdomen ran into the right labium. When the pain in the back was worst, vomiting was present, often lasting twenty-four hours ; the attacks have occurred as often as three times in a week. Examination per vaginam showed endo-cervicitis and abrasion of the os, with rents in the cervix ; on sounding the bladder, it was found to be covered all over with phosphatic concretions. I sponged out the uterus with glycer. acid, carbol., inserted a watch-spring pessary to secure rest, and washed out the bladder twice a week. This treat- ment was .so far successful, that after a time I lost sight of her. In July 1884, she appeared again, and I then found that, although tlie bladder was entirely free from phosphatic plates, the right kidney liad become very much enlarged, and could easily be felt. I then determined to explore the kidney. On August 4 and 6, with the assistance of Dr. C. Gosse, Dr. Corbin iciving ether, I performed nephrotomy. After opening the capsule of the kidney, which I stitched on both sides to the edges of the wound, I made an incision into the kidney, examined carefully with the finger, but could find no stone. A large drainage tube was then inserted, and the wound dressed with carbolised gauze. The spray was allowed to play freely over the part, but was not directed on to the wound. August 7. — Dressed the wound, which was apparently healed throughout its whole length ; urine passed the last twenty-four hours feebly acid, quite clear; sp. gr. 1022; patient vomiting a greenish fluid. August 8. — Urine greenisli ; sickness stopped ; dressing stained with a considerable sanguineous discharge. Urine, when tested with nitric acid, turns black ; sp. gr. 1022. August 9. — One-fiftli curdy pus in the urine; sp. gr. 1022. August 11. — Urine clearer, one-sixteenth pus only. 312 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. August 13. — Sits up; takes food well; urine contains one-thirtieth pus only ; tube discharging well. August 17. — Tube washed out twice daily with weak Condy and water ; urine slightly cloudy with pus. August 19. — Introduced sound into bladder; no stone; rather more pus in urine. August 23. — Urine contains very little pus ; patient putting on flesh, and walks about. September 2. — Patient left private hospital quite strong; urine clear; wound discharging very little. After returning home, patient had in some way caught cold, and had severe rigors and profuse sweats for many days. A Case of Nephrotomy. August 23, 1884.— Mrs. K. consulted me, with a history of gravel for years, and pus in the urine. She complains of intense pain for months in the region of the left kidney, but as she was very fat, no enlargement of the organ could be made out. Her intelligence was not of the higliest order, and I desired her to bring me a sample of the matter she passed. In a few days she brought me an eight-ounce bottle full of muco-pus. I then determined to explore the kidney, and with the assistance of Dr. Jay, who gave ether, I performed the usual operation for nephrotomy. The kidney was plainly seen at the bottom of a deep pit, caused by excessive deposit of fat, and after fixing its capsule, I cut into the substance, and explored the interior, but found nothing abnormal. The wound was dressed in the usual way, and a drainage tube inserted. Healing went on rapidly, and in a few days the drainage tube was removed. She left the private hospital on September 17th, well. In conversation with her on the day after the operation, I discovered that she had made up the bottle of pus, by pouring off the clear urine every day, and storing up the nmco-pus. Case IV. — Nephrorraphy. Mrs. G., a?t. 45, consulted me on the 6th September, 1884, for excruciating pain under the ribs on the right side, and below the right shoulder blade. Has eleven children, youngest three years of age. She showed me a lump on the right side of the abdomen, which could be freely moved about, either downwards to level of iliac crest, laterally beyond the median line, and backwards it could be disj^laced so as to be lost under the edge of the liver. It was perfectly smooth on the surface, and about the size of an ordinary kidney. I diagnosed " movable kidney," and told the patient's husband, that if at any time they could assure me that the pain was unbeai^able, I would cut into the loin and stitch the kidney to the edges of the incision. In the beginning of December she returned to say that she could bear the pain no longer. Accordingly, on 4th December, with the assistance of Drs. Way and Gosse (Dr. (Jraham, of Melbourne, being pi-esent), I cut down by the usual incisif)n in the loin, I then opened the capsule, and put in two steadying stitclies, which I passed through the sides of the incision. Finally, I passed two chromicised kangaroo tendons through tlie substance of the kidney, and about two iiiches apart ; then passing an THE SUKGERY OP THE KIDNEY. 313 unthreaded needle down through tlie incision on each side, T drew out the kangaroo ligatures and tied them tightly, after inserting a drainage tube in the lower angle of the wound. The operation was done under thymol spray (1 in 1000), and dressed with thymol gauze. The progress of the case was very slow, owing to the foi'mation of a burrowing abscess under the fascia, necessitating incision and the insertion of a drainage tube. The collection of matter could be distinctly felt just inside of the anterior superior spinous process of the ilium. Tliis abscess was probably caused by the decomposition of blood whicli had forced its way down under the fascia. The tinal I'esult of this case was excellent, tlie patient being now entirely free from her old pains, and able to walk about with comfort. The kidney can be felt obscurely in its normal position, and does not undergo the slightest change of position during the movements of the patient. Case VIT. — Nephro-Lithotomi/. Daniel D., set. 23, consulted me lirst on January 29, 1887, complain- ing of pain in the left lumbar region, from which he has sufiered for the last three years. Whenever he walks or runs, the urine becomes like blood ; and on passing it, he has pain across the lower part of the abdomen. When the pain is very severe, he has to make water frequently, and sometimes there is a difficulty in starting the stream. Three years ago last November, was working at a dam with an excavator, and while running across it he fell down on his left side, and twenty minutes after, on attempting to make water, he passed jjure blood. This continued for a month. Has never been able to do a hard day's work since, without feeling the pain. In every severe attack, has had pain in the left testicle. Family history good ; previous healtli good. Has not suffered from any A^enei'eal disease. Heart and lungs noi-mal ; sounded, no stone or stricture. There is undoubted tenderness over the left kidney, detected by bi-manual palpation. Microscopical examination of the urine showed pus and blood-corpuscles, and abundant ciystals of oxalate of lime. After a careful consideration of the case, the diagnosis made was probable oxalate of lime calculus in the left kidney. On the 10th February, the patient was placed under the influence of ether by Dr. Lloyd, and a transverse incision was made in the left lumbar region, about four inches long, and three-quarters of an inch below the twelfth rib. The dissection was continued downwards, through the muscles and the lumbar aponeurosis, and the quadratus lumborum was divided for one inch. Tlie bleeding was controlled by the application of pressure forceps, and the separation of the supra-renal fat and capsule of the kidney was made by tearing with the two fore- fingers. The kidney could then be plainly felt and seen, and a fine trocar was thrust into it, and gave the peculiar grating feeling caused by striking calculous matter. The kidney was then incised till the point of the trocar was reached, and then a small stone was felt, resting in one of the calyces below the incision. By means of the left fore-finger in the wound, and a small pair of lithotomy forceps passed into the kidney by the right hand, the stone was delivered. The wound was then douched out with warm thymol solution, and two large drainage tubes 314 IXTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. inserted into the post-renal cavity, and the edges brought togetlier with interrupted sutures of silver wire and wallaby tendon alternately. The stone weighed twenty-five grains, and consisted of oxalate of lime. February 10, 7 p.m. — Rallied well after the ether, temperature 98°, vomited twice, some pain in the back, pulse very good. 9.30 p.m. — Passed O ss. of urine, mixed with much blood. 12 p.m. — Temperature 101*2°. 12.30 p.m. — No sleep, restless, and in some pain; slight discharge showing at lower part of tlie dressing ; salicylic wool applied. February 11, 9 a.m. — Pulse 88, respiration 20, temperature 99 -0° ; air-bed ordered; dressed; no blood in the tubes. 6 p.m. — Tempei'ature 100°. 8 p.m. — Sleeping soundly ; discharge has not come through dressings. February 12. — Slept fairly well through the night; pulse 88, tempera- ture 99-6°; dressed, wound quite sweet, and urine not so highly coloured with blood. 5 p.m. — Urine not passed since 4 a.m., drawn oft' (twelve ounces) with catheter, previously washed in thymol. Dressed, shortened tubes a quarter of an inch, two stitches removed. The tubes after this wei'e gradually shortened, and the wound was regulai'ly kept clean with thymol solution. February 16. — Anterior half of wound well united; allowed solid food. February 17. — Bowels acted. February 18. — One of the tubes removed. February 21. — ^Second tube was removed; no urine was passing by the lumbar wound ; dressed with red lotion. This case is i-emarkable, as being the first reported case of nephro- lithotomy in Australia. Case XIII. — Neplivo-Litliotomy hij Terrier's Trans-Peritoneal Operation. M^^s. D., a?t. about 55 years, had been several times under my care, from November 10, 1886, for slight attacks of dyspepsia. Examination of the abdomen and of the chest revealed nothing abnormal, and the urine was also found to be normal. On March 6, 1888, another attack occurred, which was not I'elieved by medical treatment ; and another examination of the abdomen was made, with tlie result of finding an enlargement of the left kidney. On March 29, I called Dr. Verco in consultation, and we concluded that there were symptoms pointing to a collection of fluid in or around the left kidney. We advised aspiration, which was carried out on March 30, and four ounces of light amber- coloured fluid were removed, without any odour of uiine. With nitrate of silver, the fluid yielded a copious white precipitate ; microscopically, there were no signs of hydatid. Professor Rennie, by chemical analysis, could only find traces of urea. We were thus left in doubt whether the case was one of hydatid or hydro-nephrosis. After the operation, the kidney swelling disappeared ; three weeks after, it enlarged again ; and with the assistance of Dr. Verco (Dr. Giles administering ether), on Api-il 18, 1888, the abdomen was opened by Langenbuch's incision, outside of the left rectus, and the parietal peritoneum was stitched to the edges of tlie wound. The visceral peritoneum was then divided, and also stitclied to the edges of the wound. The cystic swelling was then incised sufficiently to admit the forefinger, and on introducing it, THE SUnORRY OP THE KIDNEY. 315 I could feel a small piece of calculous matter al)out the size of a split pea. This I removed, and on examining still furtlier, I found a small fragment also embedded in what T liad then discovered to be the renal tissue. I tried to remove it with the nail, but found that on scratching the tissue, the stone appeai'ed to become larger ; and inserting a knife along the finger, I incised a calyx, and removed an irregularly-shaped calculus weighing ninety-six grains. There had been a doubtful history of an attack of renal colic, but it was certainly on the opposite side. A glass di'ainage-tube was inserted, and the wound dressed with gauze "and salicylic wool. The highest temperatures recorded were 99*2° on the second day, and 99 '6° on the third day ; on every other occasion the temjierature was normal. Urine was passed spontaneously on the day of operation, and the patient only vomited once after the ether. Case XIV. — Nepliredomy for Stone in the Kidney. Miss M. has been under my care for years — first for disease of the hip-joint, which I excised on May 1st, 1881. She recovered perfectly, and enjoyed fjxir health for a few years, when symptoms of irritability of the bladder came on (April 1885), and this viscus was examined with a negative result. Later on (two years ago) she had an attack of renal colic, and passed a small calculus per urethram. The patient was not able to say from which side the pain started, and I was therefore unable to say from which kidney the stone had descended. For the last year, she has been passing considerable, although varying, quantities of pus in the urine. There was no enlargement of either kidney ; but as there was a possibility of the presence of "strumous" kidney, and as the patient was disinclined to have any exploratory incision, I determined to await the further development of the case. Lately, she sent word to me that the pain had now declared itself in the right loin, and that she had decided to enter the private hospital for operation. On examination after admission, I discovered that tlie right kidney was enlarged, and the probability of stone being present decided me to operate. On July 28, 1888, Dr. Todd having put the patient under the influence of ether, I made the usual lumbar incision, and after exposing the capsule, I passed in a needle, and immediately felt the sensation of a stone. The kidney was then incised, and exit given to a large quantity of opalescent fluid, with curdy flakes in it. After this no kidney could be felt, but a thickened condition of the outer wall of the capsule. This was then dissected out, and looked like a piece of gangrenous intestine. It was tlien decided to remove the kidney, and the pedicle 'was ligatured by transfixion, and the kidney removed. Unfortunately, after examination of the removed organ, no stone could l)e found, and as the presence of the stone was certain, a further search was made, and a hard piece of fatty tissue was incised, and the stone removed. The explanation was, that in holding the kidney up to assist its removal, the stone had droj^ped down, and had been in some manner included in the part which had been ligatured. Drainage tubes were inserted, and the wound bi'ouglit together. After the operation there was vomiting of greenish fluid, which stopped after the administration of a little Ijrandy and soda. At 3 p.m. on the same day tlie temperature was 98°, pulse 120, respirations .32. Urine was j^assed spontaneously. Very little pain. Barley water was given, and at 8 p.m. the tempera- 316 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. ture was 98-2°, pulse 120, respirations 32. July 29.— Temperature 98', pulse 116, respirations 24. Twenty-four ounces of urine passed in the last twenty-four hours. Wound dressed, and injected out with boric acid lotion ; tubes removed, cleansed, and replaced. Slept well during night. Thirty-eight ounces of urine passed in twenty-four hours. On the fourteenth day after operation, the patient was allowed out of bed, and returned to her home at the end of three weeks with a small granulating wound where the tube had been removed. A NEW PROCEDURE FOR THE CURE OF CONGENITAL TALIPES VARUS AND EQUINO-VARUS. By T. N. FitzGerald, F.R.C.S.L Senior Surgeon to the Melbourne Hospital. That all the various operations designed since the time of Delpech, for the treatment of talipes, have turned out in practice w4th only more or less modilied success, is a truism that requires no re-assertion. The very number and variety of methods that are constantly being suggested, and the differences of opinion that exist as regards their respective merits, are sufficient evidence that either the nature of this deformity is not properly understood, or that, through some default, our remedial measures have not yet fallen into a really satisfactory dii-ection. In my own experience, the various surgical procedures of tenotomy, tarsotomy, and tarsectomy, combined with manipulations, are not infrequently failures ; at all events, their success is by no means com- mensurate with the promises of their originators and advocates. In some instances, the cases relapse ; and not infrequently, if the appear- ance of the foot is improved, the results, as regards the usefulness of the member, are but little better than the original condition. And if in the proceeding of tarsotomy or tarsectomy, fibrous, instead of osseous, union should happen to take place, then the state of affairs cannot be deemed satisfactory. In considering the causes of these failures from a practical and clinical standpoint, I have formed some conclusions as to the natui-e of talipes varus or equino-varus, and have in consequence been led to devise a new method of treatment. It is not necessary to enter at length into the various opinions which liave been expressed as to what joints or })arts of the foot are distorted and misplaced in this deformity ; suffice it to say, that I am entirely in accordance with Mr. Par-ker in his opinion, as expressed at the last August meeting of tlie British Medical Association, in the discussion on cluij foot. Mr. Parker considers that every structure of the foot is involved, but I also further hold tliat in severe cases, resistance to the replacement of tlie deformity results from structural clianges in the bone, CURE OP COXOENITAL TALIPES VARUS AND RQUINO-VARUS. 317 as well as tlie alteration of the relati\e positions of tlieii' articailar surfaces. This condition is very well desci-ibed by Mr. William Adams in his able work on "Club-Foot." That this is so Mr. Parker admits, but he differs in considering that it is not an essential part of the deformity. The idea that the bony change is the difficulty, is the foundation of all operations such as those devised by Messrs. Lund and Davies-CoUey. However, there is this objection to all procedures, which requii'e for their fulfilment the resection or the removal of some portion of the tarsus. The inalposition may be remedied, but it is a great disadvantage to leave the foot permanently weakened. Now I hold veiy strongly that, whatever the etiology of club-foot may be, the principal factor is impaired nutrition of the whole foot, and particularly of the bones. How this occurs " in utero " is unnecessary for me to discuss. But everyone concerned in medical pi'actice must have observed the frequency with which talipes is associated in a family (as instance the two brothers whose cases are related at the end of this paper), or in the same child, with other deformities such as hare-lip, cleft palate, spina-bifida, imperforate anus and hernia. These abnormalities are admittedly due to arrest of development ; but the cause is inexplicable. With respect to the pathology of club-foot, the following seem to me to be the anatomical peculiarities in a severe instance of equino- ^ arus : — The astragalus is displaced forwards, outwards, and downwards, so that the trochlear svirface projects in front of the tibia ; the outer side of its neck is elongated, and the head directed inwards. The scaphoid is displaced, and appi'oximated to the os calcis and inner malleolus ; the external malleolus is apparently considerably thrown backwards, but in reality it is only slightly displaced. The OS calcis is nearly vertical ; its tuberosity is drawn upwards and inwai'ds, and the whole bone generally presents a crescentic shape. The upper surface of the cuboid, and the head of the fifth metatarsal bone, are turned downwards. The tendo Achillis is nearly always contracted, and also the tibialis anticus and posticus tendons. The calcaneo-scaphoid ligament is contracted and shortened, the astragalo- scaphoid ligament is lengthened, and the plantar fascia and other fibrous structures contracted as described by orthops^jdic surgeons — this latter being the real cause of the deformity of the sole of the foot. What operative measures then can be adopted which may remedy tiiese structural changes of form, these mal-positions of the bones, without much risk to the patient, witliout weakening the foot, and by which at the same time nutrition can be improved ? In another paper, I have drawn attention to the marked effects of subcutaneous drilling and gouging in improving the nutrition and vitality of bone in cases of ostitis ; and it occurred to me that if the poorly nourished and mal-formed bones in talipes were sufficiently broken up subcutaneously, and at the same time all resisting fibrous structures were freely divided, the displacement could be rectified by a pi'ocess of forcible moulding togethei- of the bones. In this way, the osseous tissues, rendered soft and malleable so to speak, would be capable of being ci'ushed together or flattened out as occasion required. Repair would then set in, new tissue be formed, and the improved 318 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. position be rendered permanent, witli the probability that tlie whole nutrition would be improved instead of impaired, the foot strengthened instead of weakened. The operation I perform is as follows :-— An Esmarch bandage is applied from the toes to above the knee. The following tendons are then divided : the tendo Achillis close to its insei'tion, the tibialis antic us just above the ankle, the tibialis posticus about an inch and a half above the inner malleolus, in the usual way. When this part of the procedure has been completed, it becomes comparatively easy to judge the amount of I'esistance offered by the contraction of the ligaments and librous structures of the sole. The fear that the divided ends of the tendo Acliillis will not unite, if severed as directed, is, I am satisfied, groundless. It is simply necessary to see that the gap (no matter how large), which is occasioned when the parts are separated, is not oblitei^ated by the too firm pressure of the bandage. To avoid this, I protect the ends and intervening space by a piece of cardboard, over which the bandage is evenly and gently applied. This portion of the tenotomy being concluded, the plantar fascia, the calcaneo-scaphoid ligament, the deep ligaments, the abductor pollicis, and all resisting structures down to the astragalo-scaphoid articulation are freely divided. I often find it necessary to sever some of the anterior fibres of the deltoid ligament. If the artery and nerve come in the way, their incision does not seem to affect the issue in the slightest. Next comes the osteotomy, and as this is the most important part of the operation, it will be well to be somewhat full in its explanation. The instruments used are an ordinary tenotomy knife, rather long in the shaft between the blade and the handle, and a chisel (a full sized representation of which is given in the annexed diagram). The chisel is made of the finest steel, its cutting extremity is bevelled like a V, similar to Macewen's osteotome, and the stem is of a uniform size and perfectly smooth and round, and just sufliciently long that it can be grasped with the hand, and at the same time perfectly controlled l)y the forefinger resting on and commanding the blade. To one accustomed to handling instruments, the importance of the chisel being of a manageable length can be easily understood, though at the first glance it may seem an unimpoi'tant matter. To proceed, the astragalus is first divided through its neck ; to effect this, a valvular incision, just sufiiciently large to admit the chisel, is made with the tenotome, obliquely down to the bone, the knife being entered on the outside of the foot, slightly inclined from above down- wards, a little Ijackwards and inwards, behind the calcaneo-cuboid articulation, so that it passes in its course through the foot immediately in front of the ankle-joint. The tenotome being withdrawn, the chisel, firmly iield, is puslied along the channel the knife has just made, so that it impinges on the bone at the spot where the astragalus may be said to narrow to a neck. The chisel enters this constriction, and with a little force by pushing and twisting, it is manipulated in such a manner, tliat the head or part of the bone which enters into the astragalo-scaplioid joint, becomes detached from the body. The inner aspect of the foot is now attacked, and the scaphoid freely broken up subcutaneously. Tlie os calcis is now subcutaneously divided INrKKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. *318 319' IliTEECOLONIAL MEDICAL CONGKESS OF AUSTJiALASU. CURE OF CONGENITAL TALIPES VARUS AND EQUINO-VARUS. 319 obliquely, at a point just behind the posterior articulating surface, in fact separating the bone into neai-ly equal halves. A few drills are put into the cuboid to help nutrition, and this finishes the actual operation. The next aim is to mould the foot into a normal position, and to do this, considerable force is required, and it is well to have the help of a trustworthy assistant, so as to prevent fracturing the tibia or fibula close to the joint, or separating the epiphyses. The rotation of the tarsal bones may be assisted by enrolling the foot in a wet towel, or the member may be levered into position by means of a flat piece of wood firmly attached to the sole of the foot, and the OS calcis forced into place. By these means, and the exercise of a little patience, it will he found that the foot can be nearly fashioned into good position. Any little fragment of the scaphoid that sticks out, or is unduly prominent, may be hammered back by a mallet, interposing a roll of bandage between tlie foot and the blow. All that now remains is to roll the foot in antiseptic wool, and apply firm but even pressure from the toes to the knee. The limb is put in a light trough splint, wdth a foot-piece so adjusted that it keeps the foot in good position, i.e., at right angles with the leg ; the Esmarch tourniquet is then removed. In three or four days, when the superficial wounds are healed, I apply the little splint depicted in the diagram. Fig. I. shows the ball-and-socket joint. Fig. II., the foot-piece (b), on the outer side of which there is a small plate, so that the projection from the ball can be screwed into it, thus allowing the foot-piece to remain on the sole when the splint is removed. Fig. III. is a full view of the whole apparatus. The foot that has been operated upon is firndy and evenly strapped to the foot-piece (b), and the limb is laid in the splint, which is care- fully adjusted to the leg; the ball portion lying free in the socket is then screwed into the foot-piece ; the foot is then turned to the desired angle, and is held in position by tightening the screw c in Fig. I. For a fortnight, the case requires careful watching, and should be seen almost daily, in the event of any undue pressure occasioning sloughing. At the end of this time, when the foot is taken down and examined, it may require some little re-adjustment, and should be f)ut up again for another week. The whole splint, with the exception of the foot-piece, should be now removed every morning, and gentle passive motion used, and the child may be permitted to walk on the foot-piece. xYt night-time, the splint should be put on, and the foot adjusted to the position desired. At first sight, this operation, no doubt, appears rough and unsurgical from the amount of force that is required to twist the foot, but the same is the case with many other proceedings, the utility of which is not in the least doubted. A question that naturally arises is, whether there is not, in breaking up the .scaphoid and chiselling ofF the head of the astragalus, a risk of separating the fragonents from their attachments and nutritive supply, thus setting up necrosis 1 Such has never occurred to me, and I think the danger apprehended rather chimerical, provided that the cutting is strictly subcutaneous, and that absolute cleanliness is rigorously observed. 320 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. 8ome of my cases have been sent from the Melbourne Hospital for inspection. The little fellow, Simon T., who walks so well and straight, was one of the worst forms of double equino-varus. The operation was performed witliin the last three months at the hospital, and was witnessed by several gentlemen present. The little boy, John B., aged 6, with the thin legs, but large fedt, was an extremely bad case, in fact he never walked before his admission to the hospital, three and a half months ago; he crawled on his hands and knees, or was pushed along in a small conveyance. His feet are straight and flat on tlie ground, but he does not "handle" them well yet, although he walks strongly and straightly. A most interesting feature about this case is, that the right tibia was over an inch shorter than its fellow, and that by drilling the upper and lower epiphyses the leg grew an inch in eight weeks, and is now only a quarter of an inch shorter than the left. (Photographs are given of this boy before and after operation). Out of many cases, I select for illustration the photographs of two brothers, Robert and Alfred C, aged respectively 8 and 6. They were admitted to the Melbourne Hospital, and operated vipon in the manner described. The photographs speak for themselves. Before the operation, the feet were turned so that the boys walked entirely on the outer side of them, and ambled about with the peculiar gait and roll which are seen in all cases of aggravated equino-varus. They left the hospital within two months of the operation, walking on the soles of their feet, as shown in the photograph. For the most part I find, that if the osteotomies and tenotomies are fearlessly and carefully performed at tlie time of the opei^ation, very little subsequent handling is required ; but occasionally I meet with feet where resistance to re-shaping is out of the common. These cases not only require patience on the part of the operator, but their treatment should be undertaken with e"\'ery confidence that in time they must yield to the measures adopted. I have now operated on twenty cases at the Melbourne Hospital alone during the past year, and up to the present, with almost invari- able success. In one case some sloughing took place, and for a time I was afraid that more of the foot would become involved than I cared for, but a few days relieved my fears, as the slough was merely suj^erficial. Discussion ensued. Dr. Gardner said that no one present in that theatre had ever seen better results than those exhibited by Mr. FitzGerald. It did not matter what theoretical objections they might have to the treatment — they might say it was wrong, and calculated to set u}) acute inflammation, but in the face of what Mr. FitzGerald had done so many times, they must be silent. He had learnt from Mr. FitzGerald the operation of drilling in bones, and he invariably drilled in suitable cases. If drilling was done in the early stage, the disease would be stayed. He was fully determined to adopt Mr. FitzGerald's method in talipes. On one or two occasions he had i)erformed, with good results, Davies-Colley's operation. He congratulated Mr. FitzGerald on his excellent paper. NEW OPERATION FOR TALIPES (Mr. FitzGeralds Paper) John B.. /et. 6. BEFORE Operation.- Had Never Walked. NEW OPERATION FOR TALIPES (Mr. FitzGeralds Paper) John B. /et. 6, AFTER Operation— Stands and Walks well. NEW OPERATION FOR TALIPES (Mr. FitzGeralds Paper) R. C. AND A. 0. BEFORE Operation. NEW OPERATION FOR TALIPES (Mr. FitzGerald's Paper) R. C. AND A, C. BEFORE Operation. NEW OPERATION FOR TALIPES (Mr. FitzGeralds Paper) R. 0. AND A. 0. AFTER Operation. SUBCUTANEOUS DKILLINO FOR BONE INFLAMMATION. 321 Dr. O'Hara said he was so struck with what he heard about Mv. FitzGerakl's operation for talipes, that he availed himself ' of the opportunity he had had of going to the hospital to see him operate. When he saw him at work, he was perfectly thunderstruck. It seemed as if he could mould a foot to whatever shape he wished. Mr. FitzGerakl's operations would sui)ersede several of the old-fashioned ones. Dr. Eexdle said they might look upon Mr. FitzGerald's paper as one of the most original and valuable that had been bi'ought before the Congress. He was struck with the originality and completeness dis})layed in the operations. One great advantage over the operations of cutting out was, that Mr. FitzGerald not only set up new action and relieved irritation, but he preserved the attachment of the' ligaments and tendons. That was a great point, and one which would make his cases more successful than those of other operations. It was well- known how unsatisfactory the old method had been. He had watched the practice in Guy's Hospital in London, and he must say that the cases in wdiich there w^ere satisfactory results were very few indeed. He never saw there any cases at all equal to those shown them that day. Even Mr. FitzGerald, with his great originality and courage, would hardly have dared to perform the operation on the tarsus, if he had not had previous experience of drilling in ostitis and bone disease. He was quite converted to Mr. FitzGerald's operation for club-foot. Dr. C. S. Ryan said he rose to express the admiration he felt on seeing one of the operations performed. He had had the privilege of being present when Mr. FitzGerald operated on the boy Hennessey. If any- body had then told him that he would see that boy walk on the soles of his feet he would not have believed him. However, it had happened, and it was one of the greatest triumphs of the day. Since then, he had seen two cases equally satisfactory. He did not think anybody who had seen those cases would fail to be convinced that there was a great deal in the operation. Since seeing them, he had done two himself at the Children's Hospital, and the results were in every degree satisfactory. No operation but that performed by Mr. FitzGerald would have given such satisfactory results. SUBCUTANEOUS DRILLING IN THE TREATMENT OF BONE INFLAMMATION. By T. N. FitzGerald, F.R.C.S.L Senior Surgeon to the Melbourne Hospital. I wish to bring before you briefly the method of treating chronic and sub-acute inflammations of bone which I have practised for very many years. Of its efficacy, I am convinced by constant verification ; and it attacks a condition of inflammation which, owang to the aiifitomical relations of the pai-t implicated, is particularly inaccessible to the ordinary means at our disposal. The method consists in subcutancously puncturing the bone in many places with a drill inserted through a valvular skin opening; this Y 322 INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. prevents the access of air, and renders the proceeding truly aseptic. In tliis way, I frequently apply the drill to the shaft and extremities of the tibia, to the trochanter femoris and the cervical portion of the bone, to the bones of the tarsus and metatarsus, to the corresponding bones of the upper extremity, and to the lower jaw, for chronic inflammation and sub-acute exacerbations of the inflammatory j)rocess of these bones. Believing that the terms periostitis, osteomyelitis, and endostitis are founded on theoretical rather than practical reasons, I have no hesitation in passing the drill through and through the medullaiy cavity, and in scoring the periosteum deeply with a tenotome. From anatomical conditions, inflammations in any one of the difierentiated portions of bone must implicate the other component parts, either by their intensity or their long continuance. This pathological consideration, this recognition of ostitis as an aflTection of the whole bone, has an important bearing on the treatment ; this can be tested clinically by the use of the drill and the tenotome, and the treatment of chronic bone inflammations ought to include the use of both instruments. There is little use in trying to combat bone inflammation with remedies which from all time have proved so efiicient in inflammations of other textures. Rest, moist heat, depletion, and counter irritants are here, by themselves, almost unavailing. In the soft parts, where the tissues have become engorged and constricted with exudations, and strangulation is imminent, relief may occur by increased activity of the absorbents immediately outside the area of turmoil, and if the condition must end in necrosis, nature can remove the necrosed portion. But for bone there is no such succour, no such vent ; enclosed in unyielding, indistensible channels, the unaflfected healthy lymphatics lying just outside the inflammatory focus can neither increase in size, nor perform much more than their usual tasks. Within the area, for a while, all is stagnant, till tension-relief can be effected by slow expansion and absorption of the bone channels, resulting in that rarefaction of the osseous tissue which affbi'ds suflacient room for the exudation, without that pressure which ends in death. The qviestion of pressure is, undoubtedly, the imjjortant one in all inflammations of bone. Clearly then, in the treatment, the relief of tension by assuring efiicient drainage is the prominent point. The essential feature of bone inflammation is the plugging of the nutritive and natural drain channels ; and therefore, for restoration, the removal of all inflammatory products is imperative. In this direction, the surgeon can come to Nature's aid by the use of either the trephine or the drill. When a bone cavity can be accurately diagnosed, or when it is required to evacuate pus, or free sequestra, the trephine, as suggested by M. Oilier, is an instr-ument that is perfect in its action, and effects exactly what is desired. However, the smallest instrument inflicts a considerable wound, which, whilst it remains open, is at any time subject to infection. There is always more or less liability of severely injuring the periosteum, or occasioning bleeding, and it is an appliance a surgeon would reluctantly use in instances where the diagnosis was SUBCUTANEOUS DIULLlNr; FOR BONE INFLAMMATION. 323 floubtful. On the other IuiikI, the drill tluit ] have been in the habit of using weekly for the last twenty years, is a surgical instrument that, in most regions, is easy of application. The subcutaneous incision through wliich the blade passes to reach tlie bone is of the smallest calibre, and the pain resulting fi-om tlie drilling, as a rule, scarcely amounts to an ache, which soon passes off. There never is, and never can be, the slightest danger of conveying any infection if oi'dinary cleanliness be observed. Again, T am constantly in the haV)it of drilling bone tissue, of which I am doubtful, and T feel sui'e I have saved many a limb in consequence. If it does no good, it can do no possible harm. It is advisable to use it several times, in fact in eight or ten different places around the suspected area, i)enetrating to the medulla or right through the cancellated structure on each occasion ; but I must repeat, that I never fail to see that perfect cleaiiliness is observed. With this precaution, the results obtained have been most satisfactory. To relate the history of even some of the many cases in which the drill has shown its utility, would be to occupy too long a time ; aiid besides, ostitis is of such frequent occurrence, that any surgeon can easily test the efficacy of my method himself. But I will take the liberty of enumerating a few of the affections where this instrument, in my hands, has proved eminently successful. The drill I generally use is Woake's, as supplied by the instrument makers, but I now prefer a moditication of the boat builder's bradawl, fitted to a proper handle; the shaft is square, and easily passes through ordinary bone tissue. The patient here presented to you, Mr. P., is 25 years of age, a clerk. For the last two years, he has had repeated attacks of severe localised inflammation of the right tibia, just below the head, and extending down the shaft for about three inches. He generally obtained relief after a week's rest, and by the application of leeches and hot fomenta- tions, with the internal administration of iodide of potassium, and occasionally a Dover's powder at night. Mr. P. was brought to my consulting room in great agony. I caused him to be placed under the influence of an an?esthetic, and at once, subcutaneously, put eight drills into the medullary canal, ordered the limb to be supported by a flannel bandage, and that the patient should rest for two days. You see him here, seven days after the operation, without a limp; he will tell you that he has no pain, and that he is better than he has been for a length of time. It may be said that the relief will be only transitory, but the records of a large numbei- of similar cases prove otherwise. For instance, under almost exactly the same conditions, T operated on a bank inspector, seven years ago, Mr. M. (well known in this city), who had been a very great sufferer for years, and periodically liad exacerbations of acute tibial ostitis of a very severe character, with nocturnal pains so great that he had to resort to narcotics. A long incision was made by a surgeon down to the bone, dividing the perios- teum to the extent of over three inches. Until the wound healed (some eight weeks) he was fairly free from pain, l)ut it at once le- commenced the moment the wound closed. In my consulting room, and witliout an anaesthetic, I put a few drills subcutaneously rigiit through tlie bone. Mr. M. was able to attend his office two days y 2 324 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. afterwards, and has not had the least pain since, and is in the enjoyment of perfect health. For this form of affection I ha\e drilled, successfully, most of the long bones, and continue to do so weekly. The OS calcis is not uncommonly the seat of a form of gouty ostitis, which does not easily give way to ordinary treatment. I find that half a dozen drills, three inserted obliquely on each side, with a little additional treatment, relieve pain, and soon restore the heel to its normal condition. Allow me here to gi-\"e one instance : — J. C, an auctioneer, a tall, stout, heai'ty-looking man of about 60, had been a great sufferer from pains in both heels, aggravated considerably by M-alking or standing. He had several attacks of gout, and believing these pains to be dependeiit on this affection, resorted to the usual anti- gout treatment, but without much relief. He also tried all kinds of circular pads, etc., endeavouring to take off the weight from the sore spots. In this case, and without an amesthetic, I drilled both heels as described. Mr. C limped away from my rooms, and was able to attend at his office two days afterwards. It is now two years since the bones were drilled, and Mr. C. remains quite free from his old pains. In articular ostitis, when from extension of the inflammation or interference with nutrition tlie joint trouble begins to show itself, it is really wonderful what the timely and free application of the drill will do. A case, for instance, that came under my notice, is a good illustration: — A girl, a't. 16, was admitted into Ward 5, under my care, at the Melbourne Hospital. Her history was that nine weeks previously, whilst running after a cow, she slipped and fell somewhat heavily on her hip. She did not feel very much pain at the time, and was able to go about with a limp for several days after her fall. On rising in the moniing, the joint was very stiff, and she was unable to mo^"e it vintil, as she expressed herself, "the hip got warm." At the end of a week, she began to feel a deep-seated pain in the hip, and the pain increased at night time, or rather towards early morning. tShe continued to move abovit, but with increasing difficulty, till the end of the third week, when she took to bed, and the family doctor was called in. Under treatment, she improved to a certain extent, but could not walk without pain, and she was oliliged to take a sedative to i-elie^e the nightly jiains. On admission to the hospital, evidence of liaving gone through pain or trouble was plainly written on her countenance. The left leg was apparently elong- ated and slightly abducted; the limb could be moderately adducted, but this caused pain. There was a form of solid cedema around this hip joint, but superficial manipulation could be borne. However, deep pressure caused pain over tlie trochanter, but not down tlie shaft of tlie femur ; slight fluctuation could be detected in the hip joint. Eight drills wei'e inserted subcutaneously into the trochanter, and two sent along into the neck of the bone. The joint was sulicutaneously opened by a tenotome from beliind, and a rather free cut made into tlie capsule. A 4 11). weiglit was attached to the foot in the usual way, and sand bags placed on eacli side of the limb ; the next day, pain had disappeai'ed. In a fortniglit a leather splint was applied, and the patient allowed up. The girl left the institution within a month perfectly well, and is now in good liealth, and walks without the slightest lameness. The same form of treatment equally applies to other joints. 325* INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. SUBCUTAXEOUS DRILLING FOR BONK INFLAMMATION. 325 A sliort account of a knee-joint case may be interesting. The patient, /Ion. As the result of an enquiry, made in the year 1885, I am able to state on the authority of Dr. W. R. Kynsey, the principal medical officer of the colony, that " there is absolutely no hydatid disease in this country. I have gone carefully over the hospital post-mortem books, and am unable to trace any cases of disease in connection with hydatids, and our post-mortem examinations are most carefully made." During the twenty-two years, 1863 to 1884 inclusive, the number of deaths registered in the colony was 1,109,724, and not one was from echinococcus. British India — Province of Madras. Dr. G. T. Thomas has kindly investigated the records of the Madras General Hospital for many years past, and could find only five cases of hydatid disease among the vast number of patients, native and Eui'opean, that have been treated within its walls ; of these, four were Europeans, and one a Hindu. As regards the organs invaded — two were in the liver, two in the lungs, and one in the right ventricle of the heart. One of the " Europeans " was an Australian jockey. Surgeon Sturmer, who had been ten years in Madras, and was also Secretary to the Surgeon- General, had seen only two cases — one in a European woman, the other in a native woman. Dr. Thomas adds, " Hydatid disease is said, by all of the profession, to be very uncommon in the Presidency, or this part of it. The returns from the out-lying dispensaries show hydatids as occurring seldom, if ever ; they may, of course, have occurred, and been returned under headings of other diseases." It is curious, that while hydatid disease is so rare in man in this part of India, it is yet common in the domestic herbivoi'a. Thus, James Mills, Esq., Inspector of Cattle Diseases of the Army Veterinary Department, in the Madras Presidency, wrote to me that, " echinococcus veterinorum is most common in Madras ; and at the slaughter-houses, the cysts found in the livers of sheep can be coiuited by hundreds daily ; as far as I have seen, they are not so common in cattle." The Presidency of Bengal. Here, as in Madras, echinococcus is very I'are in man. In the Medical College Hospital, between May 1866 and the end of 1884, there were treated as in-patients, 21,043 male Europeans, but among them, no case of this disease. During the years 1876 to 1884, inclusive,, 11,873 male natives were treated, also with no case of hydatids. Finally, out of 13,504 women (native and European) admitted between April 1878 and the end of 1884, only one case of hydatids occurred. In the catalogue of the museum of the Medical College Hospital, Calcutta,, HYDATID DISEASE. 337' there are four specimens of hydatid of the liver; one only of these died at the hospital — two of these certainly came from Europeans. J)r. D. Cr. Crawford, to whom I am indebted for much information relative to this subject, in Bengal, also e.xamined the post-mortem books of the Medical College Hospital, with the following results : — Surgical cases from October 8, 1873, to June 26, 1884, 498 cases, no hydatids; medical cases, from Se))tember 29, 1873, to January 1, 1885, 1836 cases, with one hydatid — this was in a Hindu male. In another large hospital in Calcutta, viz., tlie Mayo Native Hospital, during the years 1876 to 1880, inclusive, one case of hydatid of the liver was treated. The Presidency European General Hospital, Calcutta, founded about 1780, contains a little over 200 beds, but retuinis only one case of hydatid disease. The North-West Provinces and the Punjauh. Surgeon-General S. C. Townseud, C.B., reported in 1882, that — "no hydatid diseases have ever l)een recorded at Amritsar or Peshawur." At Lahore, however, four cases of echinococcus in natives were met with between the years 1863 and 1881. From the Delhi Civil Hospital, Eamkiishen (Assistant-Surgeon) reported — •" No cases of hydatid cyst have been observed in this hospital, either in the wards, among the out- patients, or in the post-mortem room." The Bomhay Presidency. Dr. Hatch, Surgeon to the Jamsetjee Jeejeebhoy Hospital, has kindly sufjplied me with the following facts : — In the hospital referred to, during the years 187r) to 188.3, inclusive, 70,254 in-patients were treated, with one case of hydatid disease-— in a man, who died after an operation by puncture. In the Goculdas Jeypal Hospital, Bombay, during the years 1874 to 1884, inclusive, 22,873 in-patients were under treatment ; among them were two cases of echinococcus disease — one in the liver, the other connected with the bladder. From the preceding data, it will be seen that throughout the whole of India, echinococcus is rare in man; this is remarkable, inasmuch as the jiarasite is very connnon in the domestic herbivora, at any rate, in some parts of India. Hydatid Diseases in the Colonies of Australasia. It has long been known that hydatid disease is very common in some parts of Australia, and references have been made to its prevalence by various writers. For instance, so far back as April 1861, Di-. R. F. Hudson remarked that hy'datids were becoming common in Melbourne, and he "ventured to predict that hydatids would become of frequent occurrence in Australia." Subsequent experience has proved the sound- ness of Dr. Hudson's judgment. The principal sources of information here, as in Europe, are the hospital statistics and the bills of mortality. Victoria. I am indebted to the kindness of Mr. H. H. Hayter, the Government Statist of Victoria, for a complete record of the number of deaths, registered as due to hydatid disease, for the past twenty-five years. They appear in Table IV. It will be observed, that 901 cases of death from this cause have been registered during the period in question ; of z 338 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. these, 509 occurred in males and 392 in females. The percentage of the total mortality, attributable to echinococcus disease, varied in different years from 0-152 in 1871 to 0495 in 1879, the average being 0-323. There has been a gradual increase in the numVjer of deaths from this cause. This is well seen, if we compare the five quinquennial })eriods embraced in the past quarter of a century : — Fh-st quinquennium 18fi3-1867 79 cases Second „ 1868-1872 116 „ Third „ 1873-1877 191 ,, Fourth „ 1878-1882 251 „ Fifth „ 1883-1887 264 „ 901 „ The increase in the number of deaths registered from hydatid disease, is probably due to several causes, viz. :—(l) The population of the colony has grown rapidly, for example : — Estimate.! population in 1865 621,095 1875 791,399 „ „ 1885 991,869 But this, alone, cannot explain the increase in the number of deaths attributed to echinococcus, for in the fifth quinquennium there were more than three times as many deaths registered (from this cause) as in tlie first quinquennium ; but the population, meanwhile, had increased only by a little more than one-half. It is evident, therefore, that other causes contribute to increase the number of deaths registered from this disease. (2) Probably the disease is becoming better known, both to the general j)ublic and the medical jjrofession ; and thus, deaths due to it are more frequently recorded correctly. (3) There is reason to feai- that the disease is actually more prevalent than formerly. As might have been expected, a considerable proportion of the deaths from this cause occurred in the hospitals of the colony. From data courteously supplied by Mr. Hayter, it appears that more than one-third of the deaths from hydatid disease, during the ten years 1872 to 1881 inclusive, took [jlace in the hospitals. Hospital /Statistics. — As the result of an extensive enquiry made in the year 1880 (for details, see "Hydatid Disease, with Sjiecial Reference to its Prevalence in Australia," by J. Davies Thomas, M.D., Adelaide, 1884), over 1000 cases were found to have been treated in the hospitals of the colony. Taking the gross results, it was ascertained that about one, out of one hundred and seventy-five of all cases admitted into the Victorian hospitals, was a case of tliis disease. In the following hosintals, during the period over which their returns extended, there were said to have been no cases of echinococcus treated, viz.: — Belfast, Mansfield, Swan Hill, Maldon, Portland, and Warrnambool. The highest i)roportion of cases was found in the Alexandra, Wood's Point, Horsham, and Sand- liurst Hospitals; but as the three first-named hospitals had only a small numljer of in-jiatients under treatment, but little weight can be attached to their apparently liigh proportion of hydatids. Tlie case, however, is different as regards Sandliurst ; where, during the twenty-two years over which the returns extend, there were treated as in-patients 14,058 persons, including one hundred and fourteen cases of hydatid disease, being at the rate of about one to every one hundred and twenty-three in-patients treated. HYDATID DISEASE. 339 Table IV. — l\ible shoivini/ the Nimiher of Persons of each Sex that Died in Victoria, from Hydatid Disease, during the Twenty-five Years, 1863 to 1887 inclusive: — Percentage of Total Deaths Year. Males. Females. 2 Total. Caused bv Hydatid Disea.se. 1863 3 5 _ 1864 6 3 9 — 1865 9 6 15 . — 1866 18 7 25 — 1567 13 12 25 — 1868 •21 12 33 0-329 1869 12 10 22 0-208 1870 10 7 17 0-164 1871 6 9 15 0-152 1872 24 5 29 0-269 1873 17 12 29 0-253 1874 20 21 41 0-336 1875 25 22 47 0-308 1876 23 13 36 0-266 1877 24 14 38 0-298 1878 17 20 37 0-291 1879 29 31 60 U-495 1880 28 20 48 0-412 1881 30 18 48 0-390 1882 34 24 58 0-42 1883 27 29 56 0-43 1884 29 30 59 0-44 1885 29 18 47 0-33 1886 27 24 51 0-34 1887 28 23 51 0-83 509 392 901 6-461 The annual average for the twenty year.s, 1868-87, was 0-323 per cent. of the total deatli.s. It would be extremely niisleadiug to conclude that the number of cases of hydatid disease treated in any Victorian hospital really repre- sented the prevalence of the disease in the adjacent part of the country, for owing to the migratory habits of the Australian country population, this could not be the case ; a patient treated in Melbourne may have acquired his infection in Xew South Wales, &c. New South Wales. The tJnder-S(?cretary, writing under date, )Sydney, April 11^ 1878, reports that, " No sej)arate classification of hydatid disease was made before the year 1875." Dui-ing the seven years, 1875-1881, inclusive, tifty-six deaths were registered from this disease, out of a total of 75,503 deaths from all causes. This is at the rate of 0-741 per 1000. More recent returns from this colony, although applied for, have not been received. The hos])ital returns obtained from twenty-four public insti- tutions prior to the year 1879, show that out of a total of 35,760 in-patients treated, there were ninety-four cases of hydatid disease, l^eing at the rate of one out of every 3804'2 persons treated. z 2 340 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. (Queensland. From tlie published returns, it a|)pears that no particulars were supplied as to deaths from hydatid disease prior to the year 1878, but the annexed table shows tlie deaths registered from this cause from 1878 to 1887, inclusive. Table Y. — Table showing the Number of Deaths Registered from Hydatid Disease in Queensland, : — Percentage ok Mortality Due to Hvdatid Disease. Year. Males. Females. Total. 1878 2 2 1879 — 2 — 1880 1 1 1881 — 2 2 1832 2 1 3 1883 2 2 4 1884 12 13 25 1885 11 8 19 1886 7 2 9 1887 9 8 17 0-05 0-03 0-06 0-07 0-08 0-3« 0-30 0-16 033 It will be noticed, that a remarkable increase has taken place in the deaths from this cause since 1883. That this disease was formerly rare in Queensland is shown, not only by the Eegistrai'-General's returns of deaths, but also by the hospital statistics as far as these were procurable by me. It will be interesting to notice whether the spread of the pai-asite will continue in this colony. Soutli Australia. No deaths from this disease appear to have been registered before the year 1871. It is remarkable, that in different years the number of deaths from this canse has varied greatly in this colony. Table VI. — Deaths Iicgistered from Hydatid Disease in South A ustralia : — Percentage of the Total Year. Males. Females. Total. Mortality CAUSED bv Hydatids. 1871 _ 1 1 1872 — — — 1873 1 2 3 1874 — 1 1 1875 1 1 2 1876 \ 1877 r 8 3 11 1-61 per 1000 1878"^ 1 2 3 1879) 18801 1881/ 9 4 13 1-61 1882 7 5 12 2-78 1883 (; — 6 0-14 1884 9 3 12 0-25 1885 4 1 5 0-12 1886 8 1(1 18 0-42 1887 4 3 9 0-23 HYDATID DISEASE. 341 Hospital Siatidics.—Thd i)riiici])al liospitals in the colony arc. the AdeUiide Hospital, anil that at Mount Ganibier. At the Adelaide Hospital there were treated, during the thirty-six years, 1S52-18S7, inclusive, 293 cases of hydatid disease among 48,716 in-patients, or at tlie rate of one out of 1G6 in-patients treated. During the last few years, there has been a notable increase in the proportion of cases of this disease treated in this hospital. For example— the average ])ro])ortion of hydatids among the in-patients for the thirty-one years preceding 188.'5, was one out of 222 in-])atients ; it has now risen to an average of one in 166 during the last thirty-six years. During the live years, 1873 to 1877, inclusive, there were seventy cases admitted; from 1878 to 1882, inclusive, there were seventy-four cases: but during the last live years, 1883 to 1887, inclusive, the number rose to 118. This is not due to any increase in the number of in-patients treated; on the contrary, there has been an actual diminution in their number. Western A ustralia. In March 1878, the Colonial Secretary wrote that he regretted his inability to supply information as to deaths from hydatid disease, because—" Under the Eegistration Act of this Colony, it is not com- pulsory on individuals registering deaths to produce the certificate of a professional man ; consequently, causes of death in most instances are recorded in general terms." Tiie Colonial Surgeon also reported — " That no cases of death have occurred in Western Australia .from the disease in question during the period from 1878 to October 1882, the few cases that have been brought under his notice having all been successfully treated." XeiD Zealand. The returns of the causes of death were not compiled by the Registrar- General's Department ]/rior to the year 1873. The number of deaths registered from hydatids from 1878 to 1887, inclusive, appear in the table appended. Table VII. — iJt^athti from Uijdalld Disease in New Zealand: — Percentage of Total Yi;.\R. Males. 2 Females. Total, Mortality due to Hydatid Disease. 1878 4 6 0-129 1879 4 3 7 0125 1880 8 6 9 0-165 1881 3 3 0-055 1882 5 2 7 0-123 1888 1 1 0-0165 188-i 2 1 3 0-0522 1885 1 2 3 00493 1886 3 1 4 0-0652 1887 20 2 2 0-C325 In ten j-ears . . 25 45 It will be seen that the disease is not common in this Colony is also borne out by the hospital statistics. This 342 IXTEHCOLOXIAL MEDICAL COXGUESS OF AUSTRALASIA. Tasmania. Here, as in New ZeaLmd, the disease is not frequently met with. This is evident from the record of the registered deaths. Table YIII. — Deaths from Hydatid iJlsease in Tasrnavia PERrENTAfiE OF TOTA t. Yk.^r. Males. Fkmai.es. Total. MoRIAI.lTV nUE TO Hvi'AiiL) Disease. 1878 2 2 0-117() 1879 1 1 2 0-118O 1880 1 — 1 0-054() 1881 — I 1 0-0577 1882 2 2 4 0-209 1883 4 — 4 0-188 188i 2 4 0-3015 1885 1 1 2 0-0982 1886 — 2 2 0-1062 1887 1 2 3 0-1388 In teu years . . 14 13 27 Age in Relation to Hydatid Disease. No age is necessarily exempt from echinococcus disease, for whenever the ripe eggs of the ^o roper tape-worm are swallowed, infection will follow. But the chances of infection of infants and of young children are small. A sucking babe is very unlikely to receive infection in any way, and yet Cruveilhier mentions the case of a child, aged twelve days, that appeared to have a hydatid cyst ; but in this instance, there were strong reasons for doubting whether the observation was correct. I have, however, recorded (AustraUaii Medical JonrnaJ, October 15, 1882, page 438) the case of a boy, aged two years and one month, in whom T operated upon a hydatid cyst of the liver Old age gives no exemption, foi' Monod met with a case in which the patient was seventy-seven years old, and Charcot saw a hydatid in the phalanx of the index-finger of a man eighty-one years of age. From the natural history of the disease, it is evident that, other things being equal, the longer a person lives, the greater are his chances of becoming infected with echinococcus ; but on the other hand, witli advancing age, there are fewer persons left alive to take the disease. It must also be remembered that the parasite requires usually a coi\siderable time to make its presence known in the body of its liost. Probal)Iy, on an average, five or six years pass between the moment M'hen the egg is swallowed up to the time when the great size of the bladder-worm, or the accidents caused by its rupture. Arc, betray its presence. In consecjuence of these various conditions, we find that the frecjuency of the disease increases with eacli decade of life up to al:)out thirty or forty years of age ; it afterwards declines, so that after sixty it is not connnon. The age distribution of the disease is shown in the accompanying table, based on 1301 cases collected by me from \arious parts of the world. HYDATID DISEASE. 343 Table IX. — Table s/toivinr/ the J)lstribution, according to Age, of 1301 Cases of Echinococcus Disease, collected from various 2J(t'>'fs of the World :— Age. Ni'MBEK OF Cases. Peucentage. 1 to 10 years old 91 7-00 11 to 20 „ ,, 222 17-06 21 to 30 „ ,, 376 28-90 31 to 40 1, 299 22-98 41 to 50 „ 171 13-14 51 to 60 „ ji 108 8-30 61 to 70 „ .. 34 2-62 1301 100-CO With minor and probably, in a certain sense, accidental exceptions, this age distribution prevails in the case of all the organs of the body excepting the brain, in which the highest mortality from echinococcus occurs in the second decade of life. Sex IX Relation to Hydatid Disease. There seems, a priori, to exist no valid reason why, tlu'oughout the world generally, the two sexes should suffer in unequal proportion from this disease, and indeed Davaine ("Traite des Entozoaires," second edition, page 387), and other writers on the subject have usually failed to discover any such difference. If in a given country one sex suffers more frequently than the otlier, this may be due to one or both of the following causes, viz.: — (1) The two sexes may form unequal propor- tions of tlie community; or (2) The occupations and habits of tlie men and women may expose them unequally to the chance of infection. As regards the former of these factors, the numbers of the two sexes living do not difier greatly, at any rate in the case of the principal races of the civilized world. If we take the principal nations of Europe as a whole, the sexes stand thus in the population : — Males, 48-5 per cent.; female-s, 51*5 per cent. But with regard to the liability to echinococcus disease in Europe as a whole, I find, from 11-52 published cases, that tlie numbers of each sex stand thus: — Males 586, or 50-86 per cent.; females 566, or 49-14 per cent. So that in Europe in general, although tlie living females outnumber the males, yet rather moi'e males than females acquire hydatid disease. In England and "Wales, however, according to the Mortality Returns of the Registrar-General, out of 527 deaths attributed to liydatids, tliere were — Males 243, or 46-11 per cent.; females 284, or 53-87 per cent. In England, then, there is a slight but distinct preponderance of females attacked. In Iceland, this attains a still more marked degree; for it is generally admitted by physicians practising in this land, that women here are far more often the A^ictims of the disease, than men. Finsen even states the ratio to be as high as two and a half women to one man. This is not to be explained by a great preponderance of females in the Icelandic population, because from data derived from Burton (" Ultima Thule, or 344 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. a Summer in Iceland," by Richard F. Burton), I find the proportions of the sexes in Iceland to be — Males, 47*49 per cent.; females, 53-51 per cent. The cause of the preponderance of females among the sufterers from this disease in Iceland, is probably correctly stated by Finsen to be, that the domestic avocations of the women which oc'cupy them in cooking and in washing kitchen utensils, hty-four cnses of treatment by caustics, with fifty-nine recoveries and twenty-tive deatlis. The treatment in most of the cases was complicated Ijy the iuti-oduction of several methods, in addition to Recamier's caustic method. They serve to demonstrate the terriljle mortality which attend such procedures, viz., 29-76 per cent, of deaths. In 1885 I made a collection of Australian statistics of radical opera- tions for abdominal and lung hydatids, by various surgeons, and I liaA e now slightly adderl to it. They number forty-six, with eight deaths, giving a death-rate of 17 "39 per cent. I also submit a list of internal hydatids, treated in the Adelaide Hospital, from January 1, 1885, to the end of 1888. Seven cases of livei- hydatid were ti-eated with retained canula, with two deaths, or a death-i-ate of 28-57 per cent. Thirty-live cases were treated by section, with the following results: — Liver 23 . . Deaths 5 . . Cures 18 Luug 4 .. ,, ■ — .. ,, 4 Omentum 4 . . ,, 1 .. ,, H Pleura ;> .. „ — .. ,, ^ Kidney 1 .. ,, — .. ,. 1 35 6 29 That is a death-rate for section of 17-14 per cent., or on tlie whole forty-two cases, a death-rate of 19-04 per cent. In another table at the close of this paper is a collection of thirty- two cases of section occurring in my own practice, from January 1, 1885, to the end of 1888, showing 100 per cent, of recoveries in the thoracic sections, and a mortality of 6-25 per cent, in the thirty-two sections. Dr. Davies Thomas has collated the deaths and recoveries in ninety cases of hydatids treated by retained canula. The percentage of deaths is 26-66 per cent., and cures 64 per cent., the balance consisting of cases in which the result was doubtful. Part III. In the beginning of 1885, a case of hydatid of the li\er occurred in my practice, which, terminating fatally from septictemia, led me to the conclusion that danger was to be expected from allowing the cysts to be sjiontaneously expelled, or from removing them gradually with the forceps. The case was shortly as follows: — Mrs. B. consulted me for a pain in the right side of the chest, in front. Lungs and heart were found normal on examination. There was no l)ulging in the I'egion of the liver, and the lower edge was not lower than usual. The upper border on percussion was found normal in position, but there was an extension of dulness upwards at one point in the line, semi-circular in shape, and having a radius of about two inches. I determined to explore this with the aspirator, but on inserting the needle, no fluid came away, and I was forced to the conclusion that I had made a mistake; but on reaching home I luckily \)\ew through the needle on to a glass slide, and under the microscope discovered about twenty separate hooklets. I then removed subsequently part of a rib, 348 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. and incised the cyst, inserting a rubber tube. Very little came out at the operation, the mother cyst being absolutely packed tight with daughter cysts. I left the Colony at the time for my annual holiday, and the case was attended by my friend, the late Dr. Chas. Gosse, who, following the practice of that time, drew out the cysts as they appeared in the drainage-tube. Had there been an opening made in the back, and the whole of tlie contents Avashed out early in the case, I feel sure the result would have been different. This led me to formulate for myself the following rule, viz., to I'emove all cysts contained in the external envelope at the time of operation. Since that date, my practice has invariably been not to use the aspirator exce23t at the time of operation, and then only to make sure of the best point to attack the cyst. The operation consists, then, in the thorax, of resecting parts of two or more ribs, then incising the pleura, cutting through the visceral pleura into the lung, and then removing the membranes thoroughly. In the abdomen, I cut down on the most prominent part of the cyst, and if the cyst wall will hold stitches, I place a circle of stitches uniting the cyst wall to the parietal peritoneum. Then my assistant presses with a circle of sponges the abdominal wall against the cyst, and, with a sharp-pointed knife, the cyst is boldly opened for about one inch. As soon as the knife is removed, the finger enters, and large curved needles are then passed through the cyst and the abdominal wall, at fii'st at four points, and then a few secondary sutures in between. As soon as this is finished, the cyst is distended with boric lotion, and as the current returns, the membranes are gradually extruded, the exit of the mother- cyst being aided with ovum- or other suitable holding-forceps. A soft rubber tube is then inserted, and over all a dressing of carbolised gauze, followed by salicylic wool, and finally, by a large pad of oakum enclosed in carbolised gauze. The cyst is then washed out daily, in abdominal cases. In thoracic cases, douching frequently sets up violent coughing, and if so, has to be very little used, or given up altogether. In two of my lung cases, I have had an empyema form, compelling me to resect a rib and drain from the lowest point of the pleura. To obviate this in future, I intend to resect pieces of several ribs to give plenty of room, and then endeavour to unite the visceral to the parietal pleura, immediately before cutting into the cyst. The table which is here introduced, contains all my sections for hydatid during the last four years into the abdomen and thorax, and in each case, except that of Mrs. B., all the cyst, or at least the greater bulk of it, was removed at the time of operation, only small fragments appearing afterwards. Tlie i-esults are as follow : — Thoracic Sections 9 . . Cures 9 . . Deaths — Abdominal Sections — Liver .. 20 .. .,19 .. „ 1 Broad Ligament 1 .. ,,1 •• m — Kidney .. 1 .. ,,1 •• n — Omentum .. 1 .. ,, — .. >, - Totals .. .32 .. ,.30 .. „ 2 Or a mortality of 6-25 per cent, in tliirty-two operations. THE SURGICAL TREATMENT OF HYDATID DISEASE. 349 «*-! t a; cj ^ ' — _ £ tj in '^ i^ ^ a. is rf 00 •« TJ '^ • « il-fWil 3 S S :3 O =.:=■« 5 .2 a 5 C3 > ■2 ^ -s 2 i 5 ?. 4 •2 'h3 — O =3 -/: — ; q _ g "eg O a 2 a; a 5 S S 'j. s 5^ s-B^^.-: 0^ o o '■=• 1 p ci C CJ o X XT. r^ CI „ O O 'c, S 5 J O) a ^ JS o H P3 O s H H O 5 ■73 '6 ^ ■^^ ■73 13 'C r3" ^• D » r^ ;^ ic ^ ^ I ^■ > c 2 a 03 > p > p 1 P 3 ^ S 13 1-5 J 13 ■^3 . 1 2 s *o o °o S a o "o "o o o 1 5- ^ r^ ■^ •73 S 2 '"o r^ r3 r^ rs ^ r^ •J- CS 1 :/j cS 42 r5 rt rS es n:; ? U*^ -5 -^ 03 a ^i >~i >^ S a ffl W' Ph O ffi a K M K <-o o o o » in ift >o 00 00 o 00 00 00 t~ 00 m CO O) co_ 00 rH go_ r-> o^ l>r cT < ,^ ^ 00 -__ ic" »-H cc~ -^ Q »o t>- 00 I-H 'O 00 o >--5 1-1 C5 (M 1-4 M CO -3 ^ a » a OJ tc >^ o a> S a O Is 'rt < >-3 o ^ ?; o c s ;: CO > Ol qj aj 3 U) rg ^ ■^ -a ■-2 qj |5) ri °o >4 OT "" rS _3 o 'en o .3*3 O sa £ 2 o "S o o g p "3 m r2 a 'a 0)^ ■3 ^ .3 ^ - 3 « fa "3 _'g 'P CO CO Cj CO '0 £ CD CD ^ o 3 tp CO 9 a -a ." a CD OJ to "S •J2 9 A O '~^'^ "^ "Mi > oj & ^ & QJ fi o 6 H ■^ S 3 P3 H H H P5 n£ _ T 'B ■TS ^ ^ "^ ^ ; ^ r—' ^ '^" r3 ^• a> Qi QJ tu JU a> QJ m 0; p ;-( ;h ;~t i-l ;-H ^ '& ^ ^ 3 j2 a a a a a a P3 6 o d 6 6 O o o ^a B R ■^ ;_^ s- j^ ^ ;^ i^ 1^ ;^ -^ ?H ;^ '0 ;.^ H 7 Oj OJ. OJ o o a> o 0) OJ S 2 OJ ^ Q ^ti ^ ^ .g ^ ^ ^ ■^ .a la < H s H H W H H H w W H H w ;^' ^ ^ ^ w ^ '^ ^ ;;^ ^ ;-^ M ;^ to a> a> OJ OJ Oj O a> ■ZJ en CD CD >■ > >■ > > > > ^ o 13 3 ■k3 't-l W K^l hJ hi ^ hi (-:i 1-1 i^ hi H ■ «4H ., , ., 1 tt-H t4_, ■ 1 1 «4-| c+H ^*-( e^-H «4-H e*H «4-H S4-I to o o o o O o o o n r3 p— 1—; r-^ ^ r-^ 1 — ' rw ■-3 rr^ -3 rs Ti y2 a ce JS cS cS cS ce ce 03 cS c3 03 ca 03 'C ts ? 'p 'TS ■73 '« "P f^ '« TS •^ K^i >- >J >~i >> >^ P-^ p>~. !>> >j !>j ffi a" K w K M W w w w w w W ffi U 00 00 00_ 55- 00_ 00 00 2. 00 go_ CO 00 00 co_ 00 00 00 < o" ?^ >H cT rH 5r 5r c5" r-l tH co" S] ^ £" Q IN 00" «r 55" CO r-l CO" 5" t>- C^ rH rH CO fe s ^ fe [xj s s P^ Ph ^ % Pm S >H 6 l-j UJ w cc o »■ ;^' w W r^t fe 6 w d < ^ W 05 • ^ H^ H 3 d o r"! i§ s a H i==i 6 ^ i-l iH i-H t-( i-i tH i-H iM IM (M (M IN I THE SURGICAL TREATMEXT OF HYDATID DISEASE. 351 if rib in through xamina- le back, ib below s of ribs emoving- a to 2 n3 a c3 ■^ > S g bcc.2 o ^ § 2 oj a) o "S S W) g 'a o il m _a fl r; S oi to S 3 Q ■" " t, a o =3 ^ ir! a" .2 fc< o W5 ■:: _ S -1-3 O is »3 vi-i in to c a: ^ "S O •3 a -rt o cc > 53 S "g •^ tc s- -Ji •- '^ ^ g g « S c^ 2 § 'Sc 2 CD = ci" = o3 3 0) to a a p > g m P5 p ^ a ^ a, "0 CO % i 03 p. 2 _^ :2 « 3 |. a -^J " g fl =* >^ s .2 ja 2 ."2 u W)c3 1 a 2 a .2 >; H r; r^ t; l^' ^• 'C ■TS 'O ^ Oi p ? a> CU _cu K d 6 5 6 d d = P ^ (^ ;h Oi u 3 alS rg ~ J ■5 z H H H H H w w 73 ^ ti) ti iM ti ti (D tc^ a a 2 !5 O > i3 t^ >J ij ^ 3 ^ O r5 p D I5 :^ c5 ce d c3 cS ce a ci IS TS ^ '^i 13 '^ '^ ■^ >; >^^ >i >3 t»i >-. >-i ffi W w w r • ffi K a oo 00 oo" 00 00 00 o" 1-H 00 C0_ .-1 00 0" CO I— r 00 1-1 a QO" (.-0 eo" r-l CI T-l 01 i ' ^ ^ S ^ r) Canule-H-demeure. (c) The varied forms of incision operations. III. — A third grouj) of operations is constituted by a comparatively few recorded cases, where not only has the parasite been removed, but also, more or less completely, its fibrous sac as well. These operations may be regarded as " ultra-radical," in consequence both of their greater gravity, and of the limited number of cases in which they can be regarded as permissible. Before proceeding to the discussion of the claims of the different modes of treatment, it is desirable to consider briefly the nature of the conditions p)esent. In its normal state, the eehinococcus cyst lies imbedded in some organ, tissue, or " closed cavity " of its host ; almost invariably it is completely enveloped in an adventitious sac, or capsule, THE OPERATIVE TIJEATMEXT OF ECIIIKOCOCCUS CYSTS. 353 wliicli is not an integral jiait of tlie parasite, Imt is a niorhid product of the organ or tissue in Avhich tlie bladder-worm has taken up its abode ; it is, nevertheless, a structure of great importance to the parasite, for through it, by a process of diosmosis, the latter obtains its supply of ]>abu]um from the blood of its liost ; its functional integrity therefore determines whether the parasite shall dwell in plenty, or die of inanition. When the parasite, and consequently also its fibrous sac, is young, the latter is very richly supplied with blood-vessels, which are derived from the neighbouring normal vessels ; consequently, the removal of the fibrous sac of necessity entails a very abundant employment of ligatures. But from the very natui-e of the fibrous capsule, whicli consists of stratified layers of connective tissue, it tends to contract, and in doing so, to ira])air its own vascular supply; hence follow extreme induration and rigidity of the cajisule, and calcareous degeneration. This process may issue in complete calcitication of the entire sac, if it be of small size, but in the case of large cysts, the process is more or less localised ; some portions of its surface being thick, tough, and often infiltrated with calcareous salts, whilst others are much less indurated and rigid. Calcai'eous degeneration, here as elsewhere, is a necrotic change, and is in this case an indication of impaired blood supply. The effect of this alteration upon the enclosed parasite is, when it has reached an extreme degree, fatal, by cutting off its sujiply of pabulum. When the parasite dies from this cause, as is fi^quently the case, its fluid contents become more or less opaque, the scolices die and disintegrate, a putty-like matter is found between the parasite and its capsule, and ultimately nothing remains except a tough sac much contracted in size, within which are found a })utty-like mass, with the remains, if any, of the mother-cyst, variously folded and plaited in a manner resembling the aestivation of certain plants. It is important, clinically speaking, to recognise that the mere death of the parasite does not of necessity mean the cure of the host ; for it is quite common to meet with hydatids requiring operation, but in whicli the parasite is dead and far advanced in spontaneous decay. In estimating the results of different plans of treatment, several conditions have to be regaixled, viz : — (1) Tlte locality of the parasite. — It is evident that an echinococcus cyst in the female breast may be safely removed, without remo\'al of the mamma itself; whilst a colony of hydatids in the interior of the thigh bone may entail amputation of the hip joint, and so may kill the host indirectly. — (Case recorded by Kanzow and Virchow, and cited in '•Vii'chow and Hirsch's Jahresbericht," V^ol. XV., Part 1, page 341.) Then the cyst may be so })laced as to render diagnosis, and consequently treatment, impossible — for example, in the walls of the heart, in the interior of the brain, Arc. Speaking generally, the most important cases of hydatid disease, on account of their relative frequency, are those of the interior of the thorax and abdomen, and more par- ticularly those of the liver and lungs. About 72 per cent, of all cases of echinococcus disease in man occur in connection with the abdominal cavity ; but as regards individual organs, the liver is most frequently invaded (in 67 per cent.), and the lungs next (in nearly 12 per cent.) Even in the case of the different organs situated in the same cavity, the special local conditions exert a great influence both upon the prognosis and treatment. For example, echinococci of lA 354 INTEUCOLONIAL MEDICAL COXGKESS OF AUSTRALASIA. the pericardium and heart must, for the ])rescnt at least, be regarded as alike beyond the reach of diagnosis and of treatment. Echinococci of the lung are greatly affected in their career by the frequency of their rupture into the bronchial tracts. Many cases of this disease in the lungs are spontaneously cured by the elimination of the parasite through the air-passages : and, moreover, a considerable proportion of the cases of pulmonary hydatids, reputedly " cured " by tapping operations, really have recovered in consequence of the expulsion of tlie remains of the parasite by coughing, although the bladder-worm was killed by the puncture. Moreover, in the case of jjulmonary hydatids which have ruptured either spontaneously or in consequence of surgical interference, it frequently happens that bacteria are conveyed by the air entering the cavity, through the bronchial tubes which open into it, and thus putrefactive changes are induced in the contents of the sac. From this cause, pyi'exia, cough, night sweats and emaciation may arise, and the patient often prese)its the precise general aspect of a jihthisical suffei'er. In hydatids of the liver and kidney also, the existence of the natural ducts of these organs often occasions special accidents to befall them. In the case of liver cysts, bile may enter into the sac after the mothei-- cyst has ruptured, and the remains of the i)arasite or any daughter-cysts present may pass into or through the l)ile ducts, or may be arrested in them and cause jaundice. Hydatids of the kidney are particularly liable to rupture spontaneously into the pelvis of the organ, or into some other part of the urinary ducts, for more than two-thirds of the cases collected by Beraud (Beraud's " Des Hydatides des Reins," Paris Thesis, ISGl, page 47) terminated in this way. On the other hand, the spleen, omentum, mesentery, and the abdominal cavity, which often are tlie seats of echinococcus cysts, have no natural channels which can serve as outlets for the ])arasite. (2.) 77i(' age of the parasite. — With advancing age the fibrous capsule l)ecomes thicker, more rigid, and tends to undergo calcareous degeneration : it also ac(|uires more extensive and closei- connection with the adjacent structures, and in consequence, it collapses less readily when its contents are removed. I have seen a case of hydatid cyst which |)rojected from the under surface of the liver, and which extended deep into the recto- vesical pouch, where the fibrous capsule was so closely adherent to both the anterior and posterior walls of the abdomen, that it was a puzzle to discover where the intestines were placed. It is evident that, under such circumstances, much delay must occur in the process of obliteration of the cavity formerly filled with the bladder-worm, for usually the sac yields to the pressure of the stomach, intestines, Ac, and thus its opposed walls come in contact, and arc soon united by membranous adhesions. Again, when the fibrous capsule is extensively degenerated, it may become detached in larger or smaller portions during the process of cure ; this is especially apt to occur where the sac has undergone calcareous degeneration. (3.) The occurrence of suj)puration in the sac, or of putrefactive changes in its contents, with or without the accumulation of gas, exert a weighty infiuence upon the prognosis and projjcr treatment. Usually, such conditions render a radical operation imperatively necessary. In this essay, J ])roi)ose to briefly review the modes of treatment more commonly aiJoptcd for the relief of hydatid disease, especially as concerns THE OPERATIVK TRKATMKXT OF KCIIINOCOCCUS CYSTS. 3.j5 tlieir efiieacy ami their danger to life ; but, as I have elsowliere recently discussed {A>(stra/l(ni MnViral Jonrnal, 1888) at lengtli many of tlie plans of treatment, I shall here only refer to the conclusions arrived at with regard to the following methods, viz., punctures, injections, electri- city, caustics, and canule-a-demeure. It is intended, however, that the more modern methods of incision, according to the modifications of Simon, Volkmann, and Lindemann, shall receive fuller consideration. (a) Operations nv Puncture, either Aspiratory, or by Means OF A Simple Trochar and Canula. Tapjiing, at first with a common trochar of small calibre, and, after its introduction by Dieulafoy, by the aspirator and fine canulii, has been a favourite mode of treatment in most ])arts of the world where hydatid disease is met with. In has been strongly advocated by Murchison in England, by Boinet and Dieulafoy in France, by Iljaltaliu in Iceland, and by Hudson, MacGillivray, Bird, and others in Australia. Until quite recently in Australia, inincture has been the recognised regular mode of treatment for all cases of internal hydatids. This fact alone should be jjroof that sometimes cure i-esults from tapping opera- tions ; but on the other hand, it is certain that in a large proportion of eases, it fails to rescue the ])atient from death. It must also be conceded that the treatment by puncture is attractive from its sim])licity, and its apparent freedom from risk : moreover, if we accept without criticism the statements of many of its advocates, it might be concluded that failure to cure by it is oxce])tional. But a closer scrutiny brings with it much scepticism, for the statistical ulmonary hydatids also, death has been known to supervene rapidly aftei- jjuncture. [n two cases kindly communicated to me by L>r. Lonsdale Holden, of Hobart, the patients died, one in. about five minutes, the other in about half an hour after puncture with a fine trochar. Dr. Holden was inclined to regard these as deaths frou) syncoi)e. It seems to me however that, at any rate, in some cases of sudden death after the j)uncture of large pulmonary cysts, the patient has really died of suffocation, in consequence of the flooding of the 1a 2 356 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. loronchial tracts of both lungs l)y the outflow of hydatid fluid from the punctured cyst. That this accident is not more frequent under tliese circumstances is probably attributable to the fact that the collapsed mother-cyst often occludes the openings of the bronchial tubes on the ■walls of the cavity. (For a discussion of this point, see " Hydatid Disease of the Lungs," Proceedings of the South Australian I>ranch of the British Medical Association, September 1884.) In a case recorded by Schede (cited in Madelung, " Beitriige Mecklen- burgischer ^rzte zur Lehre von der Echinococcen-Krankheit," Stuttgart, 1885, p. 86), a woman, aged twenty-three, died from sufi'ocation in the course of a few minutes after an exploratorj puncture of a huge hydatid of the right lung. I have witnessed most urgent dyspncea from the same cause. When, an echinococcus cyst of the kidney is punctured, its contents may escape by the ureter into the bladder, and so become eliminated, as in a case related by Bradbury {British Medical Journal, October 6, 1887, p. 471). In the case of liver cysts, escape of the parasite by the bile ducts after puncture is not very common, probably in consequence of the compara- tively small size of the intra-hepatic ducts ; jaundice from their blockage is probably more often met with. There is good reason for believing that a large proportion of the cases of lung hydatids cured after punctxire recover simply in consequence of the expectoration of the membranes, although it is true that the puncture killed the bladder-worm, and so rendered possible its expulsion by coughing. The recorded deaths after the puncture of pulmonary hydatids appear to me to be of sufficient interest and importance to merit notice in this paper ; they are fully recorded in a table published in the Australian Medical Journal, of July 1889. In four cases, death seems to have resulted from rupture into the pleural cavity. In one, death was apparently due chiefly to a cyst of the liver that was also present. In four instances, death took place very soon after puncture ; one them admittedly died from suffocation, the others possibly from the same cause, or from shock. The i-emaining cases sank from dyspncea, pyrexia, and exhaustion. Table I. — Table showlnr/ the Besidts of Tapping Operations upon Echinococcus Cysts in various I^arts of the Body : — Failurf. of I SiTl'ATIOS OF Deaths. Not PrNCTUKE tj Reputed Result Total. Cyst. Relieved. (other openi- tioiis). j Cukes. Unknown. Liver . . 73 5 92 68 168 10 411 Lunj,' . . 14 — 20 ' 1 14 4 53 Spleen 2 — 7 4 6 1 20 Kidney — — 4 1 2 — 6 Omentum ,mes- 1 enteiy, etc. . . 1 — ^ i — 3 — 7 ' Abdomen ". . 1 — 1 1 2 10 Male Pelvis . . 4* 4 ' — 5t — 13 Total 95 5 131 73 199 17 520 • Once the bladder as well as the cyst was inmctuied ; twice the cyst was punctured per rectum, t Three doubtful cures. THE OPERATIVE TIUCATMENT OF ECniNOCOCCUS CYSTS. 357 The general conclusions to be drawn from the statistics of tapping operations, as shown in Tal>le I., are that the death-rate has been about 19 percent.; that in 46 percent, it evidently failed to cure the patients; and that, although 54 per cent, were regarded as relieved or cured, still in the majority of them the patients had not been under the observation of the operators for a sufficiently long time after the operation to justify the conclusion that a })ermanent cure had been effected. Sumjaari/ of the Results of Tapyinc/ Operations : — Deaths . . . . . . . • • • 18-88 per cent. Not relieved .. .. .. .. •• 0-99 ■Unsuccessful punctures followed by other operations 26-04 ,, Total failure of punctures . . .. .. 45-91 ,, Believed .. .. .. .. .. li"51 Eeputed cures •. .. .. ..39-56 Total successes of punctures .. .. 54-07 ,, The results of aspiratory puncture show only about half the ratio of deaths as compared with puncture with an ordinary trochar. The mortality rises with the number of tappings required. The be.st results are met with in living juvenile echinoccocci of moderate size, the worst in old degenerated or suppurated cysts. [b) The Treatment of Echinococcus Cysts by Means of Medicated Ixjections. Injections have been e.\tensively eni])loyed as adjuncts to various forms of radical operations, e.tj., in the course of treatment by caustics and by canule-a-demeure, lirc. ; their object being, partly to evacuate the solid contents of the sac, and |)artly to correct decomposition ; however, they have also had a limited use as direct parasiticides, and also, apparently, with a vague idea that they caused adhesive inflammation in the sac, and thus led to the cure of the disease; in this case puncture forms, of necessity, a part of the treatment. Out of eighteen cases in Avhich injections were employed in this manner, five died and thirteen recovered. Numerous substances have been used as injections, e.g., iodine, alcohol, carbolic acid, ox-bile, extract of male fern, A:c. ; the latest modification being that suggested by Professor Bacelli, of Rome; he advises that about ten centigrammes of the contents of the parasite should be removed, and replaced by an equal bulk of a two per 1000 solution of mercuric chloride. At present, no satisfactory conclusion can be drawn as to the effect of this treat- ment, but there seems to be no reason to expect better results from it than from the use of iodine or carbolic acid. (For a fuller discussion of this mode of treatment see the Australian MedicalJonrnal, June 1888.) (c) The Treatment of Hydatid Cysts by Electricity. Electromotive force has been tried in various forms for the ])urpose of destroying this parasite, as faradism, galvanism, and by way of electro- lysis. The last-named is the only form of application of electricity worthy of .serious consideration. It has been tried ))rincipally in cases of liver echinococci. Out of twelve cases, collected from various sources, one died; in one case it distinctly failed to cure, but in the remaining ten cases it was claimed that cure resulted. 358 INTKUCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. In one case of Splenic hydatid recorded by Magdelaine (Paris Thesis, 1868), electro-puncture was tried for one minute, but indications of peritonitis followed in a few days, and the patient was then successfully treated by Recamier's method. For the present it seems to me that the successes claimed for electrolysis in the treatment of this disease are probably referable sim])ly to the puncture which is its necessary accom- paniment. (For a further discussion of tliis subject, see the Australian Jlledical Journal, June 1888.) Radical Operations. We now arrive at the consideration of " Radical Operations." These include — (a) Caustic treatment; (6) Canule-a-demeure operations; and (c) Various modifications of incision procedures. (a) Caustics. Recamier's Method. The uncertainty of cure after tapping with a fine trochar, and the danger occasioned by the escape of the cyst contents into the peritoneal cavity when a large instrument is used, led to attempts being made to procure adhesions between the sac and the parietes by various methods. One of the earliest and most important of these, was the use of caustics, applied repeatedly at short intervals of time, until the surface of the sac was reached, or even until an opening in the sac itself was procured; the contents were tlien removed, and the effects of their decomposition were, as far as possible, corrected by the i;se of antiseptic injections. The principal chemical agents employed for this purpose were caustic potash and zinc chloride. As the process of opening the cyst by caustics was a very tedious one, many operators hastened it by making incisions to a certain depth, and then applying caustic to the floor of tlie wound, and in the majority of cases the sac itself was opened either by an incision or by puncture with a large trochar. The general results of the caustic method appear in Table II. Table II. — Shoiving the Results of Treatment hy Caustics in Ninety-Jive Coses of Echinococcus Cysts Situated in Various Organs : — OncAN Affkcted. Deaths. Failures TO CURK. ClIRFS RKSt'LT TOIAL. Liver Kidney . . Spleen . . Abtloraiiial hydatids of uncertain seat 25 3 4 2 55 2 1 1 — 2 — 1 i — 84 4 6 1 Total . . 32 2 59 2 1 95 Summarii of Tahle II. Deaths . . . . . . H;-i-(;8 per cent. Cures G2-l() Faihu-es to Cure .. .. 210 ,, llesult Uncertain .. .. 2-10 99-98 It will 1)0 seen that about one-thii'd of the cases so treated died. THE OPERATIVE TREATMENT OF ECIIINOCOCCUS CYSTS. 359 Tliis method of treatment is to be condemned for the following reasons : — • (1) Its high mortality, nearly thirty-four per cent. (2) Its extreme painful ness ; for in children it has even been found necessary to discontinue the treatment for this cause. (3) Its prolonged duration ; probably three or four months on an average are required for convalescence, which can hardly be said to begin until the motlier-oyst has escajied. (4) Its total inapplicability in some localities, e.g., fur lung hydatids, or pelvic cysts. (5) Even when applicable in a given case, it cannot be depended upon to procure etiicient adhesions. For these reasons, Recamier's treatment should forthwith pass into disuse. [h) Canule-a-demeure. The aims of this i)lan of treatment are identical with those of Iiecamier's method, viz., to establish a free o])ening into the sac of the parasite, in order to extract its contents, and at the same time to establish adhesions, in order that none of the cyst contents should escape into the peritoneal cavity ; there can be no doubt that this metliod represented a great advance upon the treatment by caustics, as is sufficiently proven by its lower death rate, and also by the fact that it can be adopted when the parasite is situated within the limits of the thoracic parietes. In ninety cases in which this treatment was employed for liver hydatids, there were tw,enty-four deaths, or at the rate of nearly twenty-seven per cent.; but this is better than the death- rate of the caustic treatment, which amounts to over thirty-three per cent. In three cases of sjjlenic hydatid, however, so treated, all proved fatal. In a large proportion of the fatal cases, death took place from septicaemia, caused principally by imperfect evacuation of the cyst contents, which generally soon become decomposed; two of the deaths from peritonitis appear to have resulted from escape of the cyst contents into the peritoneum, and in one of them the canula had slipped out of the sac. The objections to the canule-u-demeure treatment are: — (1) The uncertainty of the course of the canula. In most cases it is not difficult to avoid transfixing the intestine or stomach, but it is common to traverse the omentum ; but in the case, for example, of a pelvic hydatid projecting in the hypogastric region, it may easily happen that the iirinary Itladder may be carried up by the cyst, and that it may be transfixed by the trochar. It is needless to comment upon the probable result. (2) In the case of a deeply-seated cyst, it is quite connnon for the canula to slip out of the sac, in consequence of the collapse of the ]iarasite, caused by the evacuation of its fluid contents. I have seen fatal ])neumo-thorax caused in this way, by an attem])t to treat a pulmonary cyst by canule-a-demeure; even when a long trochar is used this may happen, and on the other hand, if the instrument be too long, it may wound the distal wall of the capsule. (3) It is practically impossible to prevent the cyst contents from becoming septic ; the amount of discharge is so great that the usual 360 IMTEKCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. antiseptic precautions fail ; indeed it is probable that if perfect asepticisia could be maintained, adhesions would not form ; this, at any rate, has been the experience of Trendelenberg with regard to Simon's operation of double puncture, in which two canulas are retained in the sac for the sole ])urpose of causing adhesions. (4) The process is a slow one, for on an average convalescence occu])ies from two to four months, and it has been known to extend to ten or twelve months; the reason of this is, that a considerable time is occupied in the process of making an opening into the sac of sufficient size to allow the mother-cyst to be extracted, and usually it comes away in fragments, and until all the solid constituents of the parasite have been removed, the sac rarely closes ; moreover, the presence of any shreds of membrane induces suppuration and decomposition in the sac, and thus tends to cause septicaemia, and to delay convalescence. (c) Various Forms op Incisiox Operatioxs. Operations by incisions upon hydatid cysts are influenced in an important manner by the precise locality of the parasite, so that it is necessary to consider separately — (a) abdominal, and (b) thoracic hydatids. Some hydatid cysts, which have their origin within the abdomen, necessitate opei'ations which invade the thoracic cavity, e.g., echinococci of the convex surface of the liver, aiTd those connected with the upper part of the spleen. In consequence of their relative frequency, the most important abdominal hydatids are those of the liver, and consequently they merit our first and most attentive consideration. The Treatiaeat of Ecliinococcus Cysts of the Liver hy various Muds of Incision Operations. The recorded cases of liver echinococci, treated by various modes of incision, comprise a motley group. The earlier cases so dealt with were usually operated on under the impression that they were abscesses pointing on the surface ; but, in later instances, the incision Avas made after unsuccessful attempts to cure the disease by other plans of treat- ment, such as tapping and canule-a-demeure. Arc. Very frequently, during the employment of the caustic treatment, the sac was opened by an incision when it was believed that adhesions had been procured ; and in other in.stances, preliminary incisions were made into, but not through, the abdominal walls, caustics being then applied to the bottom of tlie wound. In a few cases, non-suppurating hydatids were rashly cut into, without any precautions being taken to previously procure adliesions, the result generally being that the patient died quickly of peritonitis irom escape of the cyst-contents into the peritoneal cavity. Tlie danger of such a procedure soon forced itself upon the notice of operatoi-s, and thenceforth it became a recognised principle, that hydatids of tlie liver should not l)e incised, unless adhesions were believed to be present. To attain this end, caustics were used by many operators, but others regarded them as unsatisfactory, and various means of procuring adhesions were suggested and practised. For example. Trousseau had recourse to multiple acupuncture for this purpose. Begin's method THE OPEKATIVE TREATMENT OF ECHINOCOCCUS CYSTS. 3G1 consisted in reaching tlie tiuiiour by repeated incisions, the wound being meanwhile plugged with lint ; sometimes the first incision was carried down to the peritoneum, and occasionally even tlu'ough tliat structure. A modification of this procedure, resulting from the intro- duction of the antiseptic method, has been advocated and successfully practised by A'olkmann. Another plan, having a similar aim, is Simon's method of double-puncture, followed by incision. Finally, as a result of the recent advances in abdominal surgery, comes the method of treatment generally associated in Germany with the name of Lindemann, of Hanover, by which the sac is immediately incised, its contents evacuated, the lips of the wound in the fibrous capsule being securely attached by sutures to the edges of the parietal incision. Before entering into a detailed discussion of these various operations, it is necessary to distinguish between those cases in which tlie parasite is accessible through the abdominal parietes, and those in which it can be reached only by traversing the pleura, as when the cyst occupies the convexity of the liver; for it is obvious that the invasion of the pleura inti'oduces a new element of difficulty and danger into the treatment. In order to arrive at trustworthy conclusions, it is necessary also to separate those cases in which no precautions against escape of the cyst- contents into the peritoneal and pleural cavities have been taken, from those where such precautions have been taken. Also, it is needful to consider the influence of antiseptic treatment ; of complete evacuation of the solid and fluid contents of the sac ; of effective drainage, Szc. It follows that a just criticism of the results of the various incision operations is not by any means a simple matter. Operations by incision will be considered under two principal groups, viz., (n) abdominal incisions, (6) thoracic incisions. 1. — Simple Ahdominal Incisions, loithout jrrecaiUions. In.tliis class will come simple abdominal incisions in which no special precautions were taken to prevent the escape of the cyst contents into the peritoneal cavity. Many of these were operated upon under the mistaken idea that they were cases of abscess. General Results. No. of Ca^es. I'er Cent. Deaths 23 .. 38-5 Cures .. .. .. .. 34 .. o6'-> Recoveries .. .. .. 3 .. 50 GO 100-0 It will be seen by the above table that simple incision, without precautions, is a very mortal operation. Causes of Death. Cas Peritonitis certainly in . . . . . . . . 7 Peritonitis probably iu . . . . . . . . 4 Septicffimia ,. .. .. .. .. 7 Exhaustion ,, .. .. .. .. 1 Pleurisy ,, . . . . . . . . 1 Uncertain ,, .. .. .. .. 3 23 362 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Peritonitis seems to ha-\e been the cause of death in about half the fatal cases, and to have been itself occasioned by the escape of the cyst-contents into the abdominal cavity ; in one instance, however, the fatal peritonitis was produced by tlie accidental puncture of the bladder in an attempt to procure drainage. The majority of the remaining deaths were apparently due to imperfect evacuation of the decomposed cyst-coiatents causing blood-poisoning. Multiple cysts were present in five fatal cases. Cures. — In 23 of these cases it is clearly set forth that suppuration had taken place in the sac, and consequently, there is little doubt but that adhesions had formed ; indeed, in some instances, it is expressly stated that the tumour was regarded as an abscess. It would profit little to devote much space to the discussion of this form of treatment; it suffices, however, by its appalling mortality, to teach the lesson that the cyst-contents should be jealously excluded from the peritoneal cavity. This vitally important object may be attained, before the opening of the sac, as by the methods of Simon and A'olkmann, or at the time of incising the sac, as by the method of Lindemann. Simon's Operation of Double-Puncture followed by Incision. References. Simon. — Mittheilungen aus der chirurgischen Station des Kranken- hauses zu Piostock. — Deutsche KUnik, No. 43, October 27, 1866. Uterliart. — Ueber die Incision nach Doppelpunktion zur Heilung der Echinococcencysten des Unterleibes, nebst Beschi'eibung zweier Operations-fadle, welche in der chirurgischen Klinik des Rostocker Krankenhauses vorkamen. — Berliner Kiiiiische Wochenschri/f, No. 17, April 27, 1868. Wall/'. — Operative Behandlung zweier Unterleibs Echinococcen,.nel)st einigen Bemerkungen ueber f unf fruher in der hiesigen Klinik operirte Faille. — Berliner Klinische Woclienschrift, No. 5, January 31, 1870. Treiulelenhury, in Madelung. — Beitra^ge Mecklenburgischer ^rzte zur Lehre von der Echinococcen-Krankheit. — Stuttgart 1885, page 155, et seq. Recognising the dangers of permitting the escape of the cyst-contents into tlie abdominal cavity, and impressed with the disadvantages of the method of Recamier in the treatment of liver hydatids, Simon devised and practised the method of procedure associated with his name. It nnist be premised, that botli by Simon and by his followers it was considered tliat suppuration of the cyst-contents formed an essential feature of the intended process of cure ; this is clearly set forth in the contributions both of Uterhart and Simon himself {loco cit.) The plan of operation as described by Uterhart is as follows : — At the most prominent part of the tumour, or where fluctuation is most pronounced, a fine exploratory ti'ochar and canula are introduced to a depth of some inches ; the trochar is removed, and the character of the fluid that escapes is observed, in order to establish the diagnosis ; if this be satisfactorily determined, a second fine or a somewhat larger instrument is inserted at a point two and a half or three centimetres (say an inch) distant. After a part of tlie contained fluid has been permitted to flow away through the canuhv, the latter are plugged with I THK OPKRATIVK TREATMENT OF ECIIIXOCOCCUS CYSTS. 301^ cafbolisecl \\';ix, ancl a pi'otective dressing' is applied ; for the next few- days the patient must remain very quiet in ])efl. In two or three days' time a portion of tlie accumulated fluid is apage in the flow, and a peculiar tap given to the canula, such as is perceived when a piece of membrane flaps against its end in the aspira- tion of a hydatid, increased the probability of the presence of a parasite. A pair of dressing forceps was therefore pushed along the ti'ack of the canula, and the thin layer of brain tissue toni through by opening it. The finger could then be introduced into an enormous cavity, within which could be detected unruptured cysts. The fluid was allowed to run out by turning the head on its side, and the daughter-cysts washed out by a stream of solution of boracic acid, pumped in through a flexible catheter. Finally the mother-cyst presented at the orifice, and was withdrawn, partly by the traction of forceps, and partly by the lotion introduced behind it. After the emptying of the cavity, it was filled with lotion again, and this, when collected, measured sixteen ounces. The deei)er boundaries of the cavity could not be reached by the finger. It extended forward and inward from the trephine hole towards the base. The thin layer of brain tissue around the opening did not collapse, indicating probable slight adhesions between the membranes here ; hence the free way into the cavity was not lost on ren)oval of the cyst. There .seemed to be a thin bounding membrane between the cyst and the brain. A large drainage tube of red rubber was introduced, and the flaj), divided in the middle for its passage, was stitched all round with catgut sutures, and tlie wound dressed with iodoform powder and a layer of salicylic wool. The air of the room was disinfected by the carbolic acid steam si)iay during the operation. Was somewhat collapsed after the operation. Slei)t heavily. At 2 i).m., temperature 104"2° ; sponged with cold water. 4 p.m. — Temperature 10-1:'2' ; antifebrin gr. ij given. Left arm rigidly flexed at elbow, bringing the hand to the shoulder ; right eyelid closed, left partly open. Home conjugate deviation of eyes to left, but with clonic nystagmus movements to the middle line, and slightly to the right of it ; right pupil larger than the left. 7 p.m. — In breathing, right nostril dilates more than the left; eyes quiet. Tem))erature 101'4°. Swallows milk. 8 p.m. — Breathes heavily. Kesjnrations 36, pulse 136, tempera- HYDATID OF THE BRAIN. 381 ture 102°. Tremors of riglit arm, lasting a few seconds; can use it. Ti'enior of right leg. 9 j).ni. — Pulse 160, respirations 40, tem])erature 101 "4°. Dressed under spray ; dressing soake-d through with watery slightly blood-stained fluid. AEovement of the head causes tremors of right arm, and evident pain. 12 p.m. — Pulse IGO, respirations 40, temperature 102-4°. Eyes still deviated to left ; breathing heavily. Enema of egg and milk retained. Dec. 1, 4 a.m. — Pulse 160, respirations 40, temperature 103-6°. Gr. ij antifebrin, did not swallow it; urinated into the bed. 8 a.m. — Pulse 168, respirations 44, temperature 10.3". Left pupil has been contracted some hours; right dilated. Left side of face hot and flushed; right cheek cold. Kight arm stiff, adducted at shoulder, extended at elbow, extended at the basal joint of the index, flexed at the further joints. 9.30 a.m. — Enema, with antifebrin gr. ij ; and again at 1 1 a.m. 12 noon. — Pulse 152, respirations 36, temperature 103-6". Wound dressed, still abundant wateiy discharge ; slight left extei'nal squint ; swallows liquids. 4 p.m. — Pulse 136, respirations 36, temperature 104°. Has had gr. ij antifebrin every hour. Left squint gone; slight riglit external squint; eyes widely open; right cheek hot, left cold. 9 p.m. — Tempe- rature 103°. Has liad antifeb. gr. ix, in three doses. Wound dressed ; inner end of drainage pushed up close under cranial vault ; probe passed along it, does not enter a large cavity, but impinges against soft substance; little sanious fluid runs out. Tube replaced by a smaller one. Dec. 2, 1 a.m. — Pulse 132, respirations 27, temperature 104-4°. Left side of face flushed in patches; urinated ; antifebrin gr. iv given. 2 a.m. — Temperature 104-2° ; gr. iv repeated. 5 a.m. — Temjierature 103°. 8 a.m. — Temperature 104-4°, pulse 146, respirations 29. Left cheek very hot, right cool. 10 a.m. — Temperature 103-8° ; has had three doses of 4 grs. of antifebrin, one every hour. Wound : oedema of all the back part of the scalp, with tenderness; prominence with elastic tension of the flap over the trephine hole; the drainage tube spon- taneously rises out of its track; re-introduced. No sugar or albumen in urine; swallows well. 12 noon. — Pulse 128, respirations 28, tempe- rature 101°. Cheeks pale and cool; pupils nearly equal, slightly turned to the left. 3 p.m. — Temperature 100-4", pulse 136, respirations 24. 6 p.m. — Temperature 102-4°. Both arms relaxed; left pupil dilated; right contracted; l)0th cheeks cool. 8.30 p.m. — Temperature 103-6°. Pupils equal; taken 20 oz. of fluid in the twelve hours; wound dressed; antefebrin gr. iv given. 12 p.m. — Pulse 136, respirations 28, temperature 99-8°. Dec. 3, 2 a.m. — Temperature 104°. Right eye nearly closed, left half open; eyes directed to the right; antifeb. gr. iv given. 4 a.m. — Pulse 160, respirations 40, temperature 105-8°. Face flushed in patches; antifebrin gr. iv given, but was vomited. 6 a.m. — Temperature 104-2°. Quivering of the whole body for a few seconds ; face flushed ; pupils con- tracted; bowels moved. 10 a.m. — Pulse 136, respirations 36, temperature lOr. Swallows not .so well; wound dressed; tube removed and not replaced; small hernia of apparently blood clot; cedema with tenderness over back of head; slight redness around the wound. 12 noon. — Pulse ' 144, respirations 40, temperature 101-4°. Swallows well; eyes central again, after deviation to left. 5 p.m. — Temperature 104-2°, pulse 160, ■382 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. respirations 44. Antifeb. gr. iv; wound dressed; redness less; pro- trusion little more marked; cannot swallow. 6 p.m. — Temperature 103-6°. Left cheek hot, right cold; eyes turned to left. 7 p.m. — Temperature 102°. 8 p.m. — Temperature 103°. Both cheeks cold; antifeb. gr. iv. 9 p.m. — Temperature 104°. Urinated, and bowels opened ; nutrient enema given, with antifeb. gr. iv. ; right eye moving, left quiet. 12 p.m. — Temperature 104'8°. Injection of antifeb. gr. iv; right cheek cold, left hot. Dec. 4, 2 a.m. — Pulse 180, respirations 50, temperature 105-4°. Lower jaw stiff; twitching of left hand. 4 a.m. — Temperature 105-4°. Enema of antifeb. returned. 7 a.m. — Temperature 106-4^ Deviation of eyes to right ; perspiring. Has had two enemata of antifeb. g. iv. 8 a.m. — Temperature 108-4°. Died at 9 a.m. He did not recover sufficient consciousness after the operation to speak, although until the last day he was quite sensitive to irritation anywhere, and would move his hand towards the place touched. He was sponged every hour during the first two days, and then packed in wet towels every hour till death. Post-mortem, six hours after death. The measurement of the head was found to be twenty-four inches in circumference, and sixteen .and a half inches over the vertex from one external auditory meatus to the other. The centre of the vertex was eight and a quarter inches from each aperture of the ear ; so that although the bulging on the right side of the head was a]:)})arent to the eye, it was not measurable. The trephine wound was four and a half inches vertically above the -aperture of the right meatus, and obliquely four and a half inches above and behind the right external angular process of the frontal, and three and a half inches from the sagittal suture. There was some edematous infiltration of the back of the scalp, and in the right temporal region. There was a slight hernia of blood clot. The flap was not adherent to the cranial bones. The skull was considerably thinned ; the trephine wound had perforated it where most attenuated. None of the sutures had sejmrated. The dura mater was rather more firmly attached than usual ; especially was this the case on the right side, from above the trejihine wound to the petrous portion of the temporal. On opening the dura mater, a consistent layer of buttery lymph covered the brain throughout, while a thinner watery fluid was in considerable quantity. The dura mater could be easily removed from the brain beneath, excei)t at a spot on the right side, about two and a half inches below the trephine hole. Here it was firmly adherent to the subjacent parts, and an attempt to separate it with the scalpel opened the cyst cavity, with the fil>rous wall of which it had intimately coalesced. The cyst presented on the right side of the brain, on the outer and on the inferior aspect, where over an area of about four inches by two it was uncovered by brain substance, and was translucent, but tough and membranous. This part seemed to be in the Sylvian fissure. Posteriorly, it was adherent to the temporo- sphenoidal lobe, which it very slightly overlapped, and had pushed backwards. On the cerebral surface, the Rolandic fissure, the ascending pari(;tal and ascending frontal convolutions, and the first, second and third frontals were quite distinct ; but they were displaced u})wards, so that the lower extremity of the fissure of Rolando was situated nearly four inches vertically above the end of the temporo- HYDATID OP THE BRAIN. 383 sphenoidal lobe. The third frontal convolution was not perfect at its lower part, for in the posterior extremity of this, at a si)ot about an inch and a half in front of and below the lower end of the fissure of Rolando, was the perforation made at the operation. Here the brain tissue was not more than an eighth of an inch thick. Below this point, and behind it, there is scarcely any brain substance. In front, the brain tissue gradually thickened from the thinnest pellicle, and so also towards the junction of the otiter and inferior surface of the frontal lobe. On examination of the interior of the sac, it was found to be lined throughout with a continuous tough fibrous membrane, completely shutting it off from all the cavities of the brain. It had been opened at the operation almost at its highest ])oint. It was discovered to have hollowed out the anterior end of the brain. The brain tissue above it was fully an inch in thickness ; along the front surface, about half an inch ; along the median aspect, where the frontal touches its fellow, about a quarter of an inch ; along the inferior external margin, about half an inch, thinning out on the external surface and the orbital surface to nothing, as it passed backwards. The diameter of the cyst was about four and a half or five inches. The finger in the cyst passed backwards and downwards, apparently into the substance of the right temporo-sphenoidal lobe, which appeared to be hollowed out, as well as displaced downwards and backwards. On tracing up the Sylvian or middle cerebral artery, it was found to pass on the inner side of the cyst ; that is to say, the sac of the hydatid lay between the dura mater and the Sylvian artery, and could be felt hollowing out the temporo-sphenoidal lobe for a full inch and a half posterior to the line of the artery. The hydatids evacuated consisted of a considerable amount of thick gelatinous translucent mother-cyst, studded with opaque, white, elevated, closely-set spots. These under the microscope, appeared to be mam- millated projections of the same laminated texture as the rest of the membrane, and did not display any differentiated structure. There were numerous daughter-cysts of various sizes, up to that of a small walnut. There was also noticed, among the first products in wasliing out the cavity at the operation, before the removal of the mother-cyst, a mass of fibrous flocculent material, containing very minute cysts, and in which a gentleman present suggested a resemblance to the choroid plexus. It could be spread out as a thin, tangled-looking membrane. • The microscope revealed no areolar tissue nor epithelial elements, but tangled threads of homogeneous material matted together, in places enclosing, and at others bearing on their surface, microscopic cysts of various size. These had walls of homogeneous tissue, sometimes dis- playing finely concentric laminated structure throughout ; at others, and this generally in the larger ones, only at the circumference ; while the interior was gi-anular, or contained large oval dark granular bodies, with an almost black eccentric spot. Some were apparently minute daughter-cysts, without any, or with only liquid, contents ; others con- tained formed elements, })resumably scolices. There were, in other parts, easily recognised In-ood capsules, with scolices in varying number.s in their interior, or projecting singly or in masses from their exterior, or with nipple-like protrusions from their circumference. Hooklets and granular matter in abundance were dispersed over the whole field. 384 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. The foregoing case is recorded, and brought under the consideration of the Congress, as being the first in which a diagnosis of probable hydatid has been made, and its complete removal effected by operation. The diagnosis in the present case lay between effusion into the ventricles, hydatid cyst, solid tumour, and abscess. In favour of hydrocephalus, was the history of a very large head from infancy; but against it were the absence of all symptoms till seven months ago, their rapid progress since that date, the elevated tempe- rature, the one-sided paresis, and the unilateral bulging of the head. In favour of hydatid, was the asserted increase in the size of the head of late, the unilateral pain, the unilateral bulging, the one-sided paresis, the duration of seven months. The age of the patient was consistent with this supposition. In Dr. Thomas's list of cerebral hydatids, read at the session of the Congress held in Adelaide, of the cases in which the age is given, none occurred up to seven years of age, twenty-two between the ages of seven and fifteen, and only twenty-two during all the other periods of life. The situation, too, favoured hydatid ; for this is half as covnmon again on the right side as on the left. The constant elevation of temperature was against hydatid, for in a previous case under my own care it was absent, as also in other recorded instances. Intra-ci'anial sarcoma suggested itself, because of the signs pointing to the existence of some tumour. But sarcomata are by far most common during the fourth decade of life, and the bulging would be improbable if the tumour sprang from the brain tissue; and if it originated in the cranial bones, it would be less uniform, and give evidence rather of a thickening of these structures; the temperature also opposed this theory. The diagnosis of an abscess would rest on the unilateral cerebi'al symptoms, and the persistent feverishness. But there was no efficient known cause for suppui^ation, for though there was a history of a fall, yet it occasioned no head symptoms at the time, and had occurred a long while before any such arose. Bulging of the cranium is not a characteristic of cerebral abscess. Hydatid of the brain, therefore, seemed to furnish the most complete explanation of the case, and it was further just possible that suppuration of the cyst might be the occasion of the pyrexia. The localisation was simplified by the protrusion of the skull on the right side, most marked at a point about four inches above the right auditory meatus. With this situation agreed three localising symptoms, namely, the i)aresis of the left arm, the paresis of the left face, and the pointing of the left index finger, Avith spasm of the left arm, in two convulsive seizures; these would indicate mischief about the ascending frontal, and the posterior ])art of the frontal convolutions. From the position and connexions of the cyst, it probably originated in the lower and back part of the frontal lobe; in its growth it hollowed out this lobe, chiefiy in an inferior and posterior direction. It thus pushed the three frontal convolutions upwards, as well as those about the Rolandic area upwards and backwards. It then appeared in the Sylvian fissure, and crossing over this, external to the middle cerebral artery, pushed the vessel inwards towards the centre of the brain. Growing backwards still fHirther, it pressed against the temporo- spheuoidal lobe, displacing it posteriorly, and appearing to hollow it out. HYDATID CYST OF THE ZYGOMATIC FOSSA. 385 clown almost to its tip. Tlie situation of the Sylvian artery seems to indicate that the hydatid developed in the frontal lobe, and crossed the fissure to the middle lobe; and did not originate in the brain substance in the Island of Reil, or between the two lobes, and then spread both tbrwaids and backwards. In this case, the artery would most probably have been on the exterior surface of the cyst. Death resulted from general cerebral meningitis. The layer of plastic lymph in the arachnoid sac was so extensive, thick, and consistent, that it is well nigh impossible for it to have originated subsequent to the operation, only four days before. Moreover, at the seat of operation, there was adhesion between the membranes and the thin layer of brain- tissue, practically preventing the opening of the arachnoid sac at this point. Again, the hydatid had not suppurated, hence some inflammatory mischief, such as a meningitis, must have existed prior to the operation to account for the persistent pyrexia. The supposition of meningitis explains also the acute pain experienced on moving, and on px'essing the head, and the rapid retrogression in the patient's condition during the week preceding the operation. Hence, I conclude that a meningitis existed prior to my first visit, and simply progressed after the surgical interference, without being materially affected thereby, and accounted for the fatal issue. NOTES OF A CASE OF HYDATID CYST OF THE ZYGOMATIC FOSSA. By J. R. M. Thomson, M.B., Ch.B. Melb., York, Western Australia. J. M., aged 56, came under my notice on the 26th October last, suffering from a tumour in the temporal region, of which he gave the following history : — Early last May he first noticed a " lump " about an inch from the outer border of the right eye ; it gradually increased, till it attained its present size. It has never been painful. He has never had any stiffiiess of the jaw. As the lump increased in size, he began to notice a swelling inside the mouth, between the jaw and the cheek, opposite the back teeth. On the 26th October, the condition is as follows : — There is a tumour occupying a space extending from about the centre of the temporal fossa to an inch below the zygoma, and almost from the ear to the orbit. It is very tense, and the skin covering it is shiny. There is no pain nor tenderness. I made an exploratory puncture with a hypodermic syringe, and drew off" a few drops of turbid fluid, the needle being blocked with a piece of hydatid membrane. On October 30th, I made an incision from one end of the tumour to the other. I had to cut through the temporal fascia, whicli was unusually tough. I then emptied the tumour, which consisted of a hydatid cyst crammed with daughter-cysts in all stages of development, living and dead. The zygoma was completely eroded for about half an inch from Ic 386 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. its junction with the malar bone. The cyst extended deeply into the zygomatic fossa. The wound was drained, and treated in the ordinary way. It seems remarkable that the growth of a hydatid cyst should have such force as to erode bone, while it had the 0])portunity of enlarging by expanding a softer structure ; but it would appear, in this case, at any rate, that the hard unyielding bone was less resistent than the elastic fibrous structure of the temporal fascia. The choice of locality in this case is also peculiar, especially as its growth was evidently from the surface into the deeper structures. I have not been able to find a similar case recorded. CASE OF MULTIPLE HYDATID CYSTS, TREATED BY THORACIC INCISIONS— RECOVERY. By Joseph C. Verco, M.D. Lond. Joint Lecturer on Medicine in the University of Adelaide. Honorary Physician, Adelaide Hospital. And Alfred Austin Lendon, M.D. Lond. Lecturer on Forensic Medicine in the University of Adelaide. Honorary Assistant Physician, Adelaide Hospital. In view of the proposed discussion on " Hydatids," it was thought that the following case might be of interest, illustrating, as it does, the most recent method of dealing surgically with this disease. It is believed to be the only recorded instance where a radical operation has been jjerformed through the chest wall upon separate cysts in two lobes of the liver, and also where a cyst, believed to be in the left lobe, has been deliberately operated upon in this manner : — Charles D. C, fet. 14, was admitted into the Adelaide Hospital under the care of Dr. Verco, on November 24, 1886. His previous history was briefly as follows : — He was born at Robe, and when he was two years old his parents removed to Narracoorte, where he lived till he reached the age of thirteen years, both these places being situate in the south-eastern district of South Australia, where hydatid disease is very prevalent. When eleven years of age, he is said to have had inflamma- tion of the lungs, from which he completely recovered. Shortly after removing to Port Adelaide, when thirteen years old, he is said to have had a second attack, which left him with a permanent cough. In March 188G, he had considerable haemoptysis; and in June, an enlargement of the left side of the abdomen was noticed, which temporarily subsided after a second attack of haemoptysis, which was accompanied by the expectoration of "skins." His medical attendant (Dr. Mitchell) came to the conclusion that he had ruptured a hydatid cyst of the lung. In August, however, the abdominal tumoui' rcai)peared, and subsequently increased in size rapidly, while the cougli and expectoi'ation of hydatid debris continued up to the date of admission. MULTIPLE HYDATID CYSTS, TREATED BY THORACIC INCISIONS. 3S7 On admission, he was desciiljed as being pale and emaciated, tliough not feverish, but the pulse was rapid, and the respirations were forty per minute, and shallow. He was unable to lie down in bed, as the cough was aggravated by the recumbent posture. The lower part of the chest was considerably bulged out on the right side, but on the left side the prominence was much more abdominal than thoracic. The lower border of the abdominal tumour could be traced from an inch below the costal margin in the right mammary line, to about two inches above the umbilicus in the median line, and to nearly the level of the umbilicus in the left mammary line. The hepatic dulness commenced at the fifth interspace in the right niaunnary line, the left front of the chest was dull on percussion below the third i-ib, and the whole of the left axilla was also dull. Posteriorly, there was dulness over both lower lobes of the lungs, more marked, however, on the left side, where it reached to nearly the angle of the scapula. Over these dull regions, the respiratory sounds were either much weakened or abolished. Tlie cardiac apex beat was in the sixth space, rather outside the left nipj^le line, and the impulse could be seen and felt over a wide area. The pulmonary signs showed relative flattening and deficient expansion at the left apex ; but on the other hand, impaired percussion resonance, blowing breathing, and adventitious sounds at the right apex, both in front and behind, indicating, in Dr. Verco's opinion, the existence of a cavity containing a ruptured hydatid cyst, and the source of the haemoptysis and expectoration before mentioned. Dr. Verco further thought that the tumour of the left side of the abdomen and thorax was probably a pulmonary hydatid, and that the lower part of the right side of the chest was occupied by a distinct hydatid cyst, which might be either pulmonary or hepatic. On December 24th, the left side was aspirated in the anterior axillary line, at about the level of the nipple, and ^ xv of clear hydatid fluid with- drawn. On December 31st, another slight haemoptysis occurred, followed on January 5th, 1887, by the expectoration of a piece of membrane, together with J ss. of pus; another haemoptysis is reported on February 3rd. On February 11th, the right side was aspirated in the eighth interspace, and ^ xlij of clear hydatid fluid drawn ofl". From the date of admission, he steadily improved in his general health, and when discharged on April 26th, the cyst did not appear to have refilled. He was again an inmate of the hospital for six weeks, during the months of August and September 1887, and owing to the illness of Dr. Verco, was under the care of Dr. Lendon. During this time he hafl hectic fever ; the cough and expectoration were considerable, and abundant rales were audible at the right apex. Hence it was doubtful whether he might not have phthisis in addition to the hydatids. On November Sth, 1887, he was re-admitted under Dr. Lendon's care. The abdominal and thoracic physical signs had not altered much, but there was orthopncca, and so considerable was the emljarrassment of the breathing that, in spite of the unfavourable condition of his right apex, which it was still feared might jjossiljly mean phthisis (for he had had a severe haemoptysis a week before), it was decided, after consulta- tion with Drs. Davies Thomas and Way, to operate. There was a diflerence of opinion as to the precise locality of the cyst which occupied the left side of the abdomen and thorax, but Dr. Lendon was inclined to Ic 2 388 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. think that it was connected with the left lol)e of the liver, rather than with the spleen or omentum, and certainly that it was not pulmonary; and moreover, that it would be Letter to operate upon this cyst first, in order, if possible, to relieve the dyspnoea, as it was much the larger cyst of the two, and for fear that it might be less accessible if the cyst on the right side (now presumed to be hepatic) were evacuated first. Accordingly, on November 20th, the boy was placed under the influence of ether, and Dr. Lendon proceeded to operate, with the assistance of the above- mentioned colleagues. After a confirmatory aspiration in mid-axilla, a portion of the ninth left rib was excised, the pleural cavity opened, and slight pneumo-thorax caused thereby. The diaphragm was incised, and the spleen which was presenting was retracted backwai-ds, and the omentum lifted forwards. The cyst was now obvious, but quite inadherent; for certainty, it was again punctured with the aspirator needle, and then stout loops of silk were passed through in order to bring it up to the external wound, when it was freely incised, and the contents— slightly opalescent fluid, and an enormous mother-cyst — evacuated. The edges of the sac were stitched to the deeper structures of tlie wound, but not to the skin. A large drainage tube was inserted into the sac, and a smaller into the pleural cavity. Only modified antiseptics were employed, and on the fourth day the pleural tube, being blocked with solid lymph, was left out as being no longer necessary. Bile-stained serum was discharged through the large tube, which was left out on the ninth day after the operation. Very little constitutional disturbance followed the operation, the temperature being noi-mal after three days, and a gradual improve- ment of the respiratory sound was noticed over the left back. The patient left for the Convalescent Home on December 20th, to recruit for the second operation. On Deceml)er 27th he was re-admitted, ^\'ith the sinus discharging a considerable amount of bile, although a probe could only be passed in about one and a half inches. His general condition was still far from satisfactory. There were signs of active mischief at the right apex, and there were well marked hectic symptoms, but as the hepatic tumour had increased in size, so as now to reach quite to the umbilicus. Dr. Lendon decided again to operate. On January 12th, 1888, under ether, an aspirator needle was introduced into the right mid-axilla, and pus withdrawn. Part of the eighth rib was excised, and the pleui-a found to be partially adherent. The diaphragm was cut through, and the cyst seized and dealt with in the same manner as on the opposite side, five pints of fluid being evacuated. There was much less disturbance than even after the former operation, the pleural tube being left out on the fifth day, and tlie larger tube a few days later. The sinus on the left side finally closed early in February, and that on right side early in April, the boy having left the hospital some weeks previously (March 9th) in excellent health, excepting the persistent cough. Dr. Verco had meanwhile resumed charge of his wards, and the ]iatient was admitted for the fifth and last time on April 3rd, 1888, having been ailing for the previous week with pain in the right shoulder, and having coughed up about half a tumblerful of pus. He was found to be again feverish, but this was explained by the development of signs of fluid in the upper part of the right back, which an aspiration showed to be jjurulent. Accordingly, on April Gth, under ether, INJECTION OF PERMANGANATE OF POTASS FOR HYDATIDS. 389 Dr. Verco again explored the chest by an incision in the ninth right interspace, in the scapular line, without excision of a portion of ril). On introdufing his finger into the chest, he detected the abscess bulging fioui al)ove downwards; the aspirator needle was again inserted and used as a director, and the abscess freely opened, when a large quantity of pus was evacuated, without, however, any hydatid membrane or cysts ; a drainage tube was then inserted. It was evident that this collection of pus was contained in the upper pai't of the chest; and it is probable that it was connected with the cavity at the right apex, as the signs of activity in this cavity soon disaj^peared. This last sinus liealed about the end of INIay, after the patient had left the hospital, and from this date all dyspnoea, cough, and expectoration ceased entirely. Since June, he has been at work as a clerk. On Nov. 17th, 1888, he was examined by Dr. Lendon, who found him to be in robust health, and free from cough, dyspnoea, or expectoration, although at the right apex there were marked signs of consolidation (deficient expansion and percussion resonance, bi'onchial breatliing with prolonged exjjiration, and increased resonance on .speaking and whispering), more evident in front than behind. There was no abdominal enlargement, and the hepatic dulness was normal in its limits ; the cardiac apex beat was in the normal situation, but the impul.se was diffused over an extensive area. The whole chest, with the exception of the right ajiex, expanded remarkably well, and the other physical signs were, louglily speaking, normal, excepting that the breath sounds were weak at each base posteriorly. The wounds were all soundly healed, Init the skin was puckered and adherent to the periosteum, which had formed new bone, so that it would have been difficult for one unacquainted with the case to believe that so extensive excisions of ribs had been practised. TREATMENT OF HYDATID DISEAkSE BY INJECTION OF PERMANGANATE OF POTASS. By W. P. Whitcombe, M.R.C.S.E. Amongst the many and different methods of treating hydatid disease, it has long seemed to me that some means of destroying the walls of the cysts (both parent and daughter) was much required, having, of course, due regard to the safety of the patient. But it was not till May 1885 that I liecame acquainted with any solvent for them. In a paper read for me before the Victorian Branch of the British Medical Association, I described a case of multiple hydatid, occurring in my hospital practice, which (piite as a dernier ressort I treated by laparotomy, the case proving fatal. During the operation some three gallons of cysts were removed, and at the post-mortem examination, some two gallons more were taken from different parts of the abdomen. Thus we had an excellent opportimity of seeking for an agent capable of acting as a solvent. Our then resident surgeon directed the dispense ;■ to try and 390 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. find something which would thus act, and in a few days, after tryinaj many different things, he discovered that a solution of jierinanganate of potass had this power, and since then it has been my common practice to inject solutions of this salt into hydatid cysts containing, as is often the case, large numbers of daughter cysts, and as a rule with good results. In illustration of this plan, I will give a short resume of the last case treated by me in this way : — On •22nd July, 1888, I was called to see J. G., ajt. 24, by occupation a letter-carrier, i)reviously a healthy man. He was feverish, and comjilaining of pain and tenderness in left hypogastrium. After a few days' attendance, the pain being somewhat relieved, I diagnosed a large hydatid cyst in left wall of the liver. This I aspirated, but could only obtain a few drachms of the characteristic fluid, the parent cyst being literally crammed with daughter-cysts. On 2nd August, I tapped with a lai'ge trocar, leaving the canula in the wound, and introducing through it a drainage tube. Through this but little fluid escaped, and therefore in about three days I commenced injecting solutions of potass permanganate at first, but very little could be forced in. This was repeated every other day for about a fortnight, the result being that by the end of the month the whole of that cyst and its contents were dissolved, and had come away, leaving a small unhealed sinus. It was then found that there was another cyst in the right lobe of the liver. This was treated in like manner, and in about three weeks this had also come away, also leaving a sinus. These sinuses were perfectly healed by lltli October, and the })atient went to the seaside for cliange of air, returning to his duty by the end of November. Such has been the plan I have pursued during the past two years. I have always endeavoured at first to evacuate the cyst by simple tapping, with or without aspii-ation, as I have found that this treatment has been sufficient to effect a cure in the majority of cases met with — I think I may safely say in all cases where the cyst has been simple, and not containing any daughter-cysts. And I am now con- vinced that, in the injection of a solution of permanganate of potass, we have an agent which will in almost all the severer cases destroy the cysts, without the slightest danger to the patient, and will thus effect a perfect cure. UPON THE OCCASIONAL PRESENCE OF BILIRUBIN IN HYDATID CYSTS. By JouN Davies Thomas, M.D., F.R.C.S. On October 17, 1SS8, 1 operated by abdominal section upon an enormous hydatid of the abdomen in a man aged 25. When the abdomen was opened, it was found that it was nearly filled with a huge 3chinococcus cyst. The fibrous sac was inseparably adherent to the abdominal wall in front, whilst posteriorly it seemed to line the abdominal parietes, so that it was a mystery where the intestines lay. It also reached to the bottom of the pelvis, between the rectum and bladder, both of which must have been compressed, OCCASIONAL rUKSKNCK OV IJILlllUUlN IN HYDATID CYSTS. 391 Above, its u})per limit could bo reached with the fingei-, at about the margin of the thorax, on the left side of the median line ; but on the right, the sac extended to the under surface of the liver, far beyond the reacli of the finger. I felt assured that tlae parasite had originated at the under surface of the right lobe of the liver, and had grown downwards to the pelvis, almost entirely filling the abdomen. The mother-cyst was dead, and had been ruptured before the oj)eration. It was also stained deep green, apparently from bile. The daughter-cysts, which were present to the number of thousands, were of all sizes, from that of a large pin's head to that of a medium sized apple. The nuijority contained clear transparent contents, and were tense and plump ; but a great niiniber were flaccid, collapsed, with opaque walls and j)uriform (not })urulent) contents. They were for the most i)art unruptured. Inside many of these dead, but still entire, daughter-cysts, I found flakes of matter resembling in colour red sealing-wax, but of soft consistence. Upon microscopic examination, I found that the flakes in question consisted of a collection of ruddy crystals, having the fundamental shape of oblique rhombic prisms. Some were pi'esent as isolated crystals, but the majority were accumulated into irregular masses, in which, however, it was easy to recognise the forms of the component crystals. Mixed with these coloured crystals were acicular fatty crystals and numerous oil globules of all sizes. The latter were, no doubt, products of the degeneration of the cyst contents. The quantity of the red matter procurable was very small, so that a quantitative analysis was impossible ; but it possessed the following chemical characters : — Insoluble in water and in cold alcohol ; soluble in ether, and very readily so in chloroform ; from the chloroform solution there were deposited, by the volatilisation of the solvent, small oblique rhombic prisms of yellowish-red tint, quite like those found in the original red matter, and acicular crystals apparently of some fatty acid, as well as rhombic plates of cholestearin ; both the latter were colourless. The chloroform solution gave the distinctive colours of bile ])igment with Gmelin's test, and this was particularly well marked ui)on the addition of chloroform containing a trace of free chlorine. tSpectroscopically examined, the solution was found to extinguish to a great extent the blue end of the spectruu), but there were no absorption bands in the rest of the spectrum. Examination by polarised light showed the ci'ystals to be double refracting. From the preceding data, it is clear that the matter in (question was bilirubin. I must acknowledge with thanks the kind assistance given nie by Professors Eennie and Bragg, as well as by Dr. Whittell, in determining this point. The j)resence of bilirubin has been previously noticed in connection with hydatid cysts. For example, Bristovve (Path. Soc. Trans., Vol. IV., }). 166) mentions a case of degenerated hydatid in the left lobe of the liver, in every part of which numerous vermilion spots were found. These spots consisted of colourless plates of cholestearin mixed with ruby-coloured, more or less regularly rhomboidal, crystals. In June 188G, Dr. Springthorpe read a paper before the Medical Society of Victoria u[ion an interesting case, in which a very large 392 INTEHCOLOXIAL MEDICAL CONGKESS OP AUSTKALASIA. amount of this body was found in an abdominal cyst. It is not clear to me whether this cyst was originally of hepatic origin or not, and this important point does not seem to have presented itself to the writer of the paper. Apparently, however, the cyst in point was not considered to have taken its rise from the liver, for Dr. Springthorpe evidently attributes the presence of the bilirubin to altered blood effusion ; but, as lie remarks (p. 254, Australian Medical Journal, June 15, 1886) it would require about thirty ounces of blood to yield this quantity of pigment, and this loss of blood could hardly fail to assert its occurrence ioy marked symptoms. In my own case, there could be no doubt that an effusion of bile had taken place into the sac, and had not only killed the mother-cyst, but had also passed by endosmosis into many of the daughter-cysts, destroying them also. In process of time the colouring matter of the bile was precipitated as bilirubin in the interior of the daughter-cysts invaded. I believe that some flakes of bilirubin were present free in the mother-cyst, but of this I cannot be certain, for daughter-cysts may have ruptured during the operation, and so have given rise to what appeared to be flakes in the mother-cyst. DISCUSSION ON HYDATID DISEASE, A discussion was then instituted ; and on the suggestion of the Chairman (Dr. Stirling), it was agreed that, as far as possible, seeing that so little time was available, the speakers should confine themselves to questions concerning the surgical treatment of liydatid disease. Dr. Sydney Jones (New South Wales) said : — I have listened with intense interest to the papers which have just been read, and particu- lai'ly so as to the surgical treatment of hydatids. We in New South Wales do not see hydatids so frequently as our favoured brethren in South Australia, still the disease in our colony is not infrequent ; and there, as elsewhere, the most favoured localities for the disease ai'e primarily the liver, and secondarily the lung. I do not propose to occupy your time in discoursing on the various methods of treatment which have been adopted by myself in New South Wales in years gone by ; I should siniply like to record what is the ultimate opinion at which I have ai'rived after consideration of cases that have come under my observation for many years ])ast. I may say that my methods of treatment, and those, I think, of my fellow pi-actitioners, dwindle down to two — tii'st, aspiration ; secondly, direct incision, with stitching of the sac to the parietes. I am not disposed to give up asj)iration Mt toto, as I think the tendency of the pape.rs which we have just heard would induce us to do, I cannot shut my eyes to the fact that in years gone by I have operated upon scores of cases of hydatids of the liver by simple aspiration, and I have every reason to believe that, in the vast majority of those cases, an absolutn cure has taken ])lace. At any rate I have lived long enough, having bocu in practice twenty-five years, to have had frequent o])por- DISCUSSION ON llVDATIl) DISKASK. 393 tuiiity of watching' tlio cases that were operatud oti by iiio many years ago, and it is only within tlie hist six months tliat I saw two of those cases, and from the time of operation up to tlie present day, not a solitary sign or symptom of hydatids had occurred, and I do not think it is fair to say that the cyst itself may refill after an interval of ten years. Who shall say, when such a thing occurs, that there is not a formation of a fresh liydatid cyst? Who is to pronounce that such a thing is not possiljle, nay even ])robable 1 Then, Sir, the conclusions at which I have arrived, and which I now cx]>ress, are that in all cases of liydatid cyst, other than those of the thoracic cavity, which I exclude for the ))resent, our first duty is simple asjnration. In a large nund^er of cases, of course, we shall be unable to draw off" any quantity of fluid that will have any material eifect on the vitality of the [)arasite. Those are cases in which the parent cyst is completely packed with daughter-cysts. Such cases as those have occurred to me pretty frequently, and I must say, much more frequently of late years than they did in previous years. In such cases as that, of course, simi)le aspiration will be perfectly u.seless, and if I find such a result, I am prepared at once to proceed with the o])eration of cutting down and stitching the sac to the parietes, and opening and draining in the usuiil way, evacuating all the daughter-cysts, and wash- ing out, and inserting a very large drainage tube ; but as I said before, tho.se are cases that one will meet with every now and again, but there are other numerous cases in which one will Ije able to evacuate two or three pints of clear hydatid fluid. I am confident that, in the vast majority of such cases, an absolute cure will result. I am fully aware of the risk of aspiiation in thoracic cases, and I therefore have some hesitation in aspirating such cases because of the risk, which has been so well pointed out by Dr. Thomas, of rapid suffocation, which is the sj)ecial risk to which those cases are exposed ; still, if I have a case where there is distinct bulging of the thoracic wall, I should not hesitate for one moment to use the hypodermic syringe, which I think we ought to use in more instances than we do, and withdraw a portion of the contents of the cyst. Finding it to be hydatids, I should then consider it my duty to cut down and stitch the ]Julmonary and parietal ])leur{e together, and open and drain in the usual way. I have discarded altogether the other oi)erations which have been referred to, such as retained canula, caustics, injections, and all such like. I think the whole thing is naiM'owed down to the two operations which I have just described, and I think it will be of infinite regret to us all, if we discard the simple and almost perfectly safe operation of aspiration. I say perfectly safe from my own experience, because not a solitary death has ever occurred in my practice from simple aspiration. Dr. Rendle (Brisbane) said : — Although I cannot boast of a very large personal experience of hydatids, yet I was very anxious to have an opportunity of saying a few words on the subject, and this morning, when I spoke to a friend, saying that I was coming here to listen to the papers on the sul)ject, he said " That is a well-worn subject ; there is nothing new on that." I am very glad to say I was not of that opinion, and I am still less of that opinion, now that I feel that I have learnt a great deal in listening to the papers which have been rend to-day : and T think the great lesson, in spite of what my .senior, Mr. Sydney Jones, has said, that most of us, if not all, will take away 394 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. from this meeting to-day, is the great importance and the great advantage of the treatment by free incision and drainage. I think no one can forget the large number of cases where putrefaction occurs, and this is one of the greatest dangers in the treatment of this class of disease. No doubt we are able to protect ourselves from that more by operation and free incision than l)y any other operation, however careful we are in the process of aspiration. There can be no doubt, although we do not introduce any foreign element, yet the very fact of the beings dying after the operation shows that they themselves are a source of putrefaction, and consequently of danger to the host. Another great advantage of the operation by incision is, that one is better able to see where one is going, and better able to regulate the size of the operation according to the need as it arises, and a greater freedom from injury to the intestines and other structures, and a greater certainty of confirming our diagnosis, before we have gone too far in our treatment. Another thing tliat struck me was the condemnation of the subsequent injection. I could not understand why that was condemned ; and I was very pleased to hear Dr. Thomas explain that it i)revented the collaps- ing of the cyst, and the occurrence of adhesions, both of which circumstances are so desirable. With all due respect to Dr. Sydney Jones, I think it would more satisfactory if, instead of making sweeping statements about the treatment, he had brought a few statistics of his cases to show the actual number that have really recovered, and the time of observation after aspiration, and also the number of cases in which putrefaction has or has not occurred. Mr. FitzCtEUald said that the subject of hydatid disease had always been of great interest to him, and that his interest had not diminished, but rather increased, during thirty years of jiractice. He had not intended to speak, but on some ]ioints he could give definite information. Firstly, it was (juestioned whether tai)ping effected a permanent cure. Over twenty-five years ago, a lady in Melbourne came under his care suffer- ing from gastralgia. He diagnosed the case as one of hydatid of the liver, and with difficulty obtained the patient's consent to paracentesis. Dr. Bird was present at the operation. The aspirator was not used, simply the ordinary trocar. Between ten and twelve ounces of fluid were removed. The pii,tient lost all pain. Five years later, she died of apo})lexy. A ])ost-mortem examination was obtained. The mother cyst was found rolled up in the collapsed adventitia, but not adherent to it. He had seen many cases subsequently, which showed that when simple tapping was performed with success the sac contracted to very small dimensions, and then fiecpiently remained permanent, with relics of the true echino- coccus structures encapsiiled within it. He almost always tapped in the first insttince, but seldom used the asi)irator. Aspiration, when pushed too far, had, within his knowledge, caused death by h?emorrhage. He remembered only one case in which simple tajjping caused death. That occurred twenty-six years ago, in the Melbourne Hospital, in a patient under the care of the late Dr. Wilkie. The hydatid was deep in the liver, and long trocars weie not then in general use. A short trocar was inserted without result. Dr. Wilkie objected to the use of a longer instrument; deatli ensuf^d. At the auto])sy, it was foiuid that tlie sac h;i(l boon ])onetrat('d, but the mothoi- cyst had been pushed inwards by the trocar, and separated froui the adventitia; haemorrhage DISCUSSION 0\ HYDATID DISRASK. 395 had occurred into tlie s])ace so formed. He had seen no otlior case in which death could be attributed directly to tapping. Undoubtedly, tapping frequently revealed the presence of multitudes of daughter cysts. Free incision and thorough drainage were then required, and death often followed the neglect of these procedures. But, even in these difficult cases, the preliminary tai)ping did no harm, while in the simpler cases it sufficed for a cure. Surely then, it was not correct surgery to neglect an operation attended with no danger, which was thoroughly effective in a lai'ge number of instances, on the ground that in a minority of cases it needed supplementing l)y incision, evaoiation, and drainage. During tlie discussion, reference had been made to symptoms of shock after tapping. In one instance, he was treating, in conjunction with Dr. Bird, a case of multiple hydatid. The patient, a man from Queensland, was over 70 years old. The abdomen was full of cysts. One after another was tapped and emptied, till a cyst over the great end of the stomach was punctured. Pulse and breathing at once ceased, and the patient fell as if dead. He lay in a trance for eleven days. Probably some great .sympathetic reflex had been excited. However, he gradually recovered, and years later had no sign of liydatid disease. He (Mr. FitzGerald) further said that, when he determined to incise a hydatid cyst, he inserted a number of hare-lip pins, so as to .secure adhesions. If the abdomin;il wall was flaccid, he pinned the cyst to the wall ; if it was thick, he simply inserted the pins into the cyst cavity ; if the cyst was tense, he diew off a small quantity of fluid in the flrst instance. He left the ])ins in for twenty-four to forty-eight hours, though adhesions were in reality obtained in five or six hours. It was nearly fifteen years since he first incised and removed the whole parasite. But he insisted that this lai-ger operation should be restricted to cases requiring it. The recovery after sim])le tapping was sometimes startling in its rapidity. About seven years ago he saw^, with Dr. Williams, a case of large single cyst of the liver. Eight pints of fluid were removed. Within fourteen days, the patient was in the saddle in the hunting field. Two years later the |)atient reported liimself, and there were no signs of hydatid disease. Eighteen years ago, a railway ])orter presented himself with partial right hemiplegia, pain in the right arm, bulging and intense pain around the left ear. The finger in the ear detected slight crackling and semi-fluctuation on pressure. Eight ounces of fluid wei-e withdrawn with a fine trocar. Complete recovery followed. Dr. S. D. Bird said that it had fallen to his lot to see a lai'ge number of hydatid cases dating as far back as 1861, when he saw, in the Melbourne Hospital, the late Dr. Motherwell and Dr. Hudson (now present) tap many such in the liver, with the ordinary fine trocar and canula, with perfect success ; and he was informed by those gentlemen that they had heard no complaints of recurrence in the great majority of cases. A good example, amongst hundreds that might be quoted, of tlie efficacy of simple tapping, was that of a little girl from the Western district, who was so treated by Mr. FitzGerald and himself for a cyst in the liver in the year 1872, with complete recovery as usual; but the following year a cyst in tlie right lung made its appearance, which was treated in the same way with the same lesult, and some years afterwards, the young lady when presented at Coint caused a notable 39G INTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. sensation by her remarkable beauty. Sometimes violent convulsive cough, with expulsion of membranes and blood, followed tapping the lung, and even pneumothorax, but he h;id never seen death or permanent injury, or indeed any other result than cure follow this treatment. On the other hand, the use of the aspirator was distinctly dangerous. Several sudden deaths had been caused by it, even in the most skilled hands; and it also hindered, instead of aiding, the emptying of the c\\st, by sucking portions of membrane into the canula, thus giving rise to delay and trouble. For oUl suppurating cysts of the lung, a different treatment was required. In all )>robability, adhesions to tlie chest wall ali'eady existed, and all that was necessary was to introduce the largest trocar and canula that would pass between the ribs, leaving the latter in for a few days, and frequently washing out with antiseptics. The wound being now freely enlarged laterally with a probe-pointed bistoury, the whole of th^. parasite was easily removed with a little assistance, and a radical cure was effected. He had never found it necessaiy to resect any portion of rib, though some of the cysts had been of enormous size, and weighed over a pound after removal. In none of the.se cases had there been septicfiemia, or any warning of it ; the constant result had been ladical cuie in about three weeks, though sometimes separation of the cyst wall from its nidus was delayed much longer than this. So far from hydatid of the lung being a difficult disease to cure, he had found it more safely and readily curable here tlian in any other internal organ — except, perhaps, the liver — piovided the treatment was not hurried, and the aspirator was not used. He had reported a great many of these cases in the Aitstralian Medical Joiornal in past years, but of late had not done so, as he had nothing new to tell — all the cases ending in the same way. The only cases, in his opinion, in which immediate cutting operations for hydatid within the thorax were justifiable, were those in which the parasite occupied the cavity of the pleura, either by rupture from the lung or elsewhere, or by primary development. These were much more serious cases. Many years ago, he removed a large cyst which had burst from the lung into the pleura, leaving a fistulous opening and pneumo-thorax ; complete recovery followed after a pro- longed course of treatment ; but some months afterwards, during an attack of pneumonia from exposure, the fistula re-opened, and after a tedious illness the patient died of exhaustion. Primary hydatid of the pleura was very rare ; he had only seen two cases, in both of which, after operation, a secondary development of hydatid took place in the pericardium, and of course caused death. If adhesion to the chest wall did not exist in an old suppurating hydatid, his practice had been to tap with a moderate-sized trocar, and leave the canula in for a few days, when adhesion was sure to form. His experience of these plans of treatment of lung hydatid (and the same was equally applicable and successful in the liver), led him to enteitain very grave doubts as to the proi)riety and .safety of ])rimary cutting operations in non- suppurating cysts, involving such serious procedures as resection of ribs, incision of sound lung, stitching of pleura, and so on, reconnnended and ])ractised by Dr. Gar t s 1 < Ill Total. Atrophy and Debility 1058 865 363 107 287 268 2948 Diarrhoea and Dysentery 78] 802 431 94 268 337 2713 Enteritis 243 181 64 11 45 99 643 Teething 324 111 180 35 79 101 830 Tabes Mesenterica . . 269 96 58 49 51 . , 523 Gastritis and Stomach Disease 178 219 45 7 13 , , 492 Liver Disease . . 2 13 15 10 18 , ^ 58 Peritonitis 18 8 2 1 6 5 40 Cholera 81 38 23 4 16 : 10 172 Want of Breast-milk . . 79 115 28 20 29 29 , , 300 Thrush 59 19 16 9 10 17 •• 130 Total . . 3092 2467 1225 281 806 978 •• 8849 Percentage to Deaths from all causes . . . 20-23 17-17 19-65 13-80 20-21 16-08 •• 18-44 CL.4SS B.— NEKVOUS DISEASES. Total Deaths of Persons under 5 Years of Age from the undermentioned Causes in the A ustralasian Colonies during the Year 1885. : ■^AME OF Colony Disease. a; 06 1 > 13 ■ a ce a 1 _C3 Z 3 Total. Apoplexy 4 1 3 4 12 Convulsions . . 820 312 346 141 155 153 1927 Cephalitis 235 179 41 16 45 42 558 Paralj-sis 5 1 2 1 1 , , 10 Hydrocephalus 73 116 26 9 48 46 318 Brain Disease . . 5 21 26 15 27 38 . , 132 Epilepsy 15 11 7 •• 4 37 Total .. 1153 644 448 182 279 288 • ■ 2994 Percentage to Deaths from all Causes 7-54 4-48 7-18 8-94 6-99 4-74 .. 6-24 410 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Class C— RESPIRATOEY DISEASES. Total Deaths of Persons under 5 Years of Age from the undermentioned Causes in the A ustralasian Colonies during the Year 1885. ] !f AME OF Colony Disease. o "2 1 _C3 5 1 Western Australia (1886). Total. z > O" ^ < N Pneumonia 236 260 31 16 84 106 733 Bronchitis 397 288 84 48 98 168 1083 Congestion of Lungs . . 69 83 41 23 10 28 .. 2.54 Whooping Cough 108 162 28 16 87 87 488 Pleurisy 8 7 1 1 ^ 3 .. 22 Influenza 56 29 10 3 1 5 •• 104 Total .. 874 829 195 107 282 397 .. , 2684 Percentage to Deaths from all Causes 5-72 5-77 3-13 5-25 7-07 6-52 5-59 From these it will be seen that, in the case of the nutritive diseases of childhood, tlio warmer colonies, viz., Queensland, New South Wales, and South Australia, have a decidedly greater mortality ; whereas, in the colder colonies — Victoria, New Zealand, and Tasmania—infantile mortality from nutritive disorder is less. On the other hand, from respiratory diseases Queensland shows a great immunity ; but South Australia here, also, has an unfortunate pre-eminence. In nervous diseases, exemplified by convulsions, cephalitis, and so forth, Tasmania, contrary to our expectation, shows the greatest fatality, followed by New South Wales, Queensland, and South Australia. Taking it altogether, it must be observed that in all the classes of diseases of infancy, Victoria and New Zealand are decidedly the most healthy. Old age is fourth in New South Wales, is thirteenth in Queensland, eighth in Victovin, first in Tasmania, fifth in South Australia, and in Western Australia, third. In the country parts of most of the colonies, it seems, as a cause of death, to be much on an equ.ility with accidents. There are many matters connected with these tables which it would be exceedingly interesting to inquire into ; but in a brief sketch like the present, detailed inquiry necessai-ilv would be somewhat out of place, my object being to give a few of the most salient points, which are obvious on a cursory glance. I niust, moreover, remember that the time at our disposal is but limited, and that there are also limits to your patience, on which I must not encroach too much. I shall, therefore, refrain from going regularly down the columns, and shall now confine PRESIDENTS ADDRESS — SECTION OF HYGIENE. 411 myself to considering one or two of the most important diseases, espe- cially those which are generally considered the most amenable to sanitary influences. Of these, typhoid fever is certainly one of the principal, whether we consider its prevalence, the amount of public attention it excites, or the influence which sanitary improvements are believed to have in checking it. The exact details of the prevalence of this disease, during the three years under consideration, will be found set forth at length in the larger tables which I have caused to be prepared. For convenience I have, as in the case of phthisis, selected the latest year for which a retui-n common to all the colonies is in my possession, viz., 1885 ; and I have drawn up a short table, giving at a glance a compara- tive view of the mortality from typhoid fever in the various colonies during that year. And it is to be borne in mind that this is only an account of the mortality from typhoid, and that the real sickness from typhoid — that is to say, the number of persons affected by this disease ■who recovered from it, or at all events who did not die from it — cannot in any way be ascertained, there being no materials for the purpose, but must be simply estimated as a matter of speculation by each of us, in accordance with his experience of the fatality attendant upon the disease in diffei'ent places. Typhoid Fever, 1885. Name of Colony or District. Ordf.r of Fatality. Total Deaths. Rate per 100,000 OF Population. Percentage OF Deaths. New South Wales . . 12th 503 53-06 3-29 Sydney . . 9th 93 71-31 3-53 Suburbs 9th 130 85-28 3-37 Country 11th 280 42-10 3-18 Victoria 10th 424 43-48 2-95 Melbourne and Suburbs 12th 183 52-98 2-63 Country 9th 241 38-27 3-25 Queensland 3rd 541 169-90 8-68 South Australia . . 11th 145 45-34 3-64 New Zealand IGth 128 22-32 2-10 Tasmania . . 18th 30 22-42 1-47 "Western Australia (1886).. 16th 13 32-84 1-61 From this table it will be seen that Queensland is by far the greatest suffei'er from this disease of any of the colonies. In that tropical province, typhoid occupies the second place in the list of fatality, causing 541 deaths in the j'ear, an absolutely greater number than in any other colony ; the relative mortality was at the rate of 169-9 per 100,000 of the population, and the percentage to deaths from all causes was 8*68. Taking the other years in my tables, it appears that in 1884 the results were rather worse, and in 188fi rather better ; we may, therefore, assume that the results of 1885 give not an unfair idea of the 412 INTEKCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. mortality from typhoid fever in Queensland. It is certainly very high, quite sufficiently so, I think, to attract the attention of sanitary inquirers in that Colony. Leaving Queensland, which occupies an unenviable position by itself, we shall find that the death-rate in even the most populous of the other colonies is much lighter, although there can be no doubt that in some there is still a good deal of room for improvement. New South Wales is the worst, with its death-rate for the whole colony of 53-06, which rises in Sydney to 71-31, and in the suburbs to 85-28. These figures, especially the last, are far from creditable ; but I am glad to say that public attention has at last been called to this matter, and various measures have been adopted, or are in process of adoption, with a view to reducing the mortality from this disease. Of these, I may mention the Dairies Supervision Act, which was passed in 1886, and is now gradually being extended to different parts of the colony. I should also notice that the Government have in prepai-ation a comprehensive scheme of sewerage for the western suburbs of Sydney, which have hitherto been left to their own devices in this important matter. The somewhat sensational reports which from time to time appeared in the newspapers last summer as to the prevalence of typhoid fever in Victoria, would lead us to suppose that there had been at that time a considerable increase, within a comparatively recent period, in the prevalence of this disease in that colony. I am, of course, not in a position to give the number of deaths for 1888, but for 1887 there were 631, whereas in 1885 there were only 424, being at the rate of 43-48 per 100,000; Melbourne and suburbs being credited with 183 of these deaths, at the rate of 52-98 per 100,000 of the population. It would appear from these figures, that of late typhoid fever has been increasing in severity in Victoria. What may be the reason of this, I shall leave to those to say whose business it is to manage the health affairs of the colony. South Australia appears to be, as regards this disease, much on a level with Victoria and New South Wales, the mortality being 45-34 per 100,000. But when we come to consider the island colonies, we find a very different, and much more agreeable, state of matters, the death-rate falling in New Zealand to 22-32, and in Tasmania to 22-42, per 100,000. Here, then, is a problem for the sanitarians, which I trust they will lose no time in attacking, viz. : — How to reduce the 169-9 of Queensland — not to speak of the smaller figures of the other Australian colonies— to the very desirable 22-32 of New Zealand. The last disease with a notice of which I shall trouble you to-day, is one which has always attracted great attention in the different parts of Australia, viz., diphtheria. In accordance, as I believe, with the views of the best authorities, I have associated croup with it. I attach hereto PRESIDENTS ADDRESS — SECTION" OF HYGIENE. 413 a table, giving a coni])arative view of the prevalence of the disease in the diflerent colonies for the year 1885, already selected, excepting, as usual, Western Australia, for which I have only one return, viz., 1886 :— Name ok Colony ok District. Order of Fatality. Total Deaths. Rate per 100,000 OF Population'. Percentage of Deaths. New South Wales . . 10th 582 61-38 3-76 Sydney . . 46 35-27 1-74 Suburbs 91 59-70 2-35 Country 445 66-90 5-06 Victoria 14th 332 34-05 2-31 Melboui-ue and Suburbs , , 129 37-35 1-85 Country 203 32-24 2-74 Queeuslaud 9th 208 65-32 3-34 South Australia . . 7th 188 58-79 4-71 New Zealand 10th 172 29-99 2-83 Tasmania . . 13th 50 37-37 2-45 Western Austraha . . 23rd 9 22-74 1-12 From this it appears that, if whole colonies be taken, Queensland has. again a bad pre-eminence, heading the list with a death-rate of 65-32 per 100,000, to which New South Wales comes, as a veiy close second, with 61-38. If we leave out from the latter the figures for Sydney and suburbs, we find that the country districts of New South Wales surpass the whole colony of Queensland, the death-rate amounting to 66-90 per 100,000. This is another illustration of the well-known principle, that diphtheria is a disease rather of the country than the town. An apparent exception to this is shown by the .suburbs of Sydney, which, with the high ratio of 59-70, approach closely to the rural rate. This excessive prevalence of diphtheria appears to me to be, to a considerable extent, due to the absence of any systematic method of getting rid of the fiecal accumulations within these suburbs, a defect which, I am glad to say, is likely very soon to be remedied. South Australia, with its ratio of 58-79, follows close on New South Wales ; and the three colonies named are in a distinctly worse position as regards mortality from diphtheria than any of the other colonies. Thus in Victoria, the rate was only 34*05 ; in Tasmania, it was 37'37 ; in New Zealand, it was just under 30 ; while in Western Australia, it was a little over 22 per 100,000. The diffei'ence in these figures is sufficiently striking, and here again plenty of scope is offered for the exertions of sanitarians. Tliere are very many other matters of interest connected with these tables to which I might draw your attention; for example, the prevalence of diflTerent diseases in different quinquennial periods of life would afford us a most interesting suljject of study. But time will not 414 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. fillow me to enter into tlie suljject with further detail; and in fact, as you will see, I have not been able to do more than deal with it in the most superficial way, touching merely on the matters which were most obvious on the surface. But even such cursory consideration as we have been able to give to-day, is quite sufficient to show that there is an ample field in these colonies for the exercise of all means for the improvement of the public liealth. In conclusion, I venture to express the hope that our sanitarians will leave no stone unturned until they succeed in lowering the death-rates from preventable diseases in all the colonies — at all events to the minimum level which our tables show to exist in the most salubrious of our districts. And I am sure that I cannot give utterance to this aspiration more apijropriately than befoi'e the present audience, composed as it is of the most distinguished practitioners of medicine from all the Australasian colonies, and more especially of those who take particular interest in matters of public health. This great Congress of the profession, so successfully organised by our Victorian friends, ought to lead to the most beneficial results in every branch of medicine, and certainly not least are the hopes entertained from our action in the department of public health. Medical men have always been honourably distinguished by the great interest they take in sanitary matters, and it is to us that the public naturally look for guidance and advice in such questions. It is our duty to make plain to everyone what are the shortcomings of our community in questions of public health, and to show how these shortcomings can be remedied. No better opportunity can be conceived than this Congress affords for the proclaiming of our views, and it is difficult to over-estimate the influence for good which it will have with the public, who are never backward in acknowledging with respect any honest effort to advance the interest of the community. 415 -8d8n»o TIB •ooo'oox •eqfjBaa mox ?* r" y 7^ ?* 'f' ^- ?^ <» ? T' 30 ffl O in Ifl Ci 00 (Jl 00 I - C M 17I XI -p -p 7^ t_- I>1 IH Til CI -W 1^ S F- O S o S S2 S S S r' S 't; '"' 55 "^ ^ "" 00 o 1^ «'- 1- 'J' do iH 4^ o i i- I- 00 1- i o t- in •* t- tV. *• oj 000 '001 •smsaa mox '?^ T T' ■* T' ?■?'.-?=?'?"??' p ':'''?"'?' ?^ ■??"• ?^ r' ?" T' '."■?? "iP '."'."• T* T* T' T* T^ ?'?' ^ ®^ "^ '»^■-t«ooooo■^«c^•^:ooor^Ol«l-Hlftco>o«I-(^3couoo-^^cOr-^oooc/^oooooooa^'^^(^^o rMipt»';il-»ri^'^yDl^M»pW00»05'^C5O0ii;H'^ip«l;-l^'<»0000l» SS2S^£"22^^'-'i'f~'*'=''Ood»C3i^cvb-4'iii5t.oooi-'Ij<4t"oooooMiot~do Oi(OMX-OCiC5rsl-.tO-^OXlCOiA-*00(N'N05mi>-05-00'^t0e050i«lO(N(NC0C0r-(vnco05COT-HC5ioec'M — ]ocq(»o{»M^o»p»oposco*^a)cogocoC5J^^t-(>i(Nr----' — ■ — — 1 O) >o o -^ b -^ o i 1 - ^- >Jr5 -^ c-i 10 (>i (i-i 4<) 00 iJ:3 o t-- o o » C5 1^ I— I »f5 t— ■^ ■ IOt^t^lft»CC5'NCliH0005OTl^O-^Oi*OlOWOCiOO-^OOCO(M'^00'MOO tOO:C'*T-lX'»*l-lOOff^i;a'^TjfCO-«#CO0 "Tj* M (f 1 rH O O C5 t-- CD o 03 O i^ o in (X00'MO??OOOI^^I^i0Mt-»CiO:Ct^O"-0C0rNT-H-'#r-t-*'MI^OC::/^'^^T>rH05C0l^:0t» ■^:0r:i^:DCi-+'MrH'^C5r-l05-*C0r-(i-IO00 1^^C0i-i CO i-H IM 'M 1-4 - oy CO •gjBa.C oi 0% qg rao.i^ (M CO • CO -.O O • t— OIM-#C0T-l.-(MC0r-l •ai«a^ 99 o^ 09 uiojj • oot~m i-H CO I-* (N • 1- Tj4 1-4 - CO in i-l iH 50 (N CO •sreeS o9 <4 gg mo\q^ •^'MrH^Ht-t^i-tOO r-4(M »i-4 r-l OCOC^tNi-t-^-^infl •sxesi og (xj OS tao.ij o3!Di-ocoeq'<*Ti400 •saB9jC 05 o^ c^ utoj^ rH 1.0 •■* rH CO OC01>-(NffJJ-CJC0i.0rHl-»OC0 'sicaX g^ en o^ raoi j; •MBaX 0^ o^ gg moj^ C/D 1^ . 10 t- 00 (N W CO • :o CO th (MCS'MCOCOC'IOOmCO^COmcO rH <>J rH rH rH r-4 Ot^C-lintMCOOOOOiOrHCCO-^d^O •RI«a;C Qg CKt Og UtOJ^ I '* . 7-1 CO I- (N 10 O • CO CO CO ■Biv9/i 08 0% ss moa^ Ol 1-4 • CO N o c^ o w . 5.) ^ -.51 0'MCO:0^0 10 0! in C5 t- O CO ■* I- O -* •* »^ S3 CO ooci o r^ -M in 1-4 1- TJ1 c" ■ v:oi-4a5 co(Mco cofhc^ 'MC000CIOr^'Mmi-4l-TJi(M mcO»(NrH o •Tj • ;o --54 in th t- o IM o 05 in I^ in -n -)< coeoco ■^•3 •J •.C}irB}i!j JO iai(.io 5 li : to 3^3 /T ^"^'^ ^J^.^««^ -"^^ r5 ^^ ^Jx ^ ^'Z J'. ^ ^'% '-\7\*^ .t^ '"^r^, r•^fvr**':T1-#^■ic^S*i!5!-5^S 7) CO -i" I.- -O I- -/; cv o — I ■M CO -r i- -^ 1- vD o o rH ji CO ^4 i;-: o i;^ 5J> Jj g j; ; I CO Tj4 in :3 t* CO Ci o ICOCOCOCOCOCOCO-* 416 ns 5- •<£ § ■u ►«> ■^ Si. 2f5 ^ M C> ^. o o ^ <:^l o '^ ^^ 5- QO ■iJ 00 ^ ^ !^ ?; ?! Si "<£ 0% eSB^asoaaj o 'C c-i «-* o c; o -t c-i C-. o ^ r: »^ I-- o: cc -t CO -x 1- r; ^ ■s-r'TiaiO-fc.-J'.ciysmajr-OTOi-ici ICtOOi-tOCOiCOOiCi 1 ^ CO ■«♦"•*•* : 'OOO'OOT •stRBaa ib;ox 4t-o;oo':ci^cooori'ccc:cOf-HC:t*-OiCrH05(/3Ct^vcTa ~ — HiH-^C^CMC^COJCNC^rHiHrHG^IG^i-i r-i lCO»if-Hf>i^cr-^cooo-*oirs^Cii--t^i--'iHOODiniou;:iC'. (-iCO-*r-irHl-(MCO-*'l-CCOgF-iC:c '«C^4'MrHT-(OCiG:ODl-<:OiO»-niOO'-u;5Mt-i-HlQOr^-t-*iOij:3C0C0C0CN(N(NG^(NC^G^T cooMO'>Ju'too-Hr-cocc»cr--i--ocooc::^T-*r-.i'.ir;cct--coi--o*cC')»nrHCOCj^t^cD^cor^ t-t-OOSOt^t-SOtOCOCOTlxNegCNCNIMr-tr-llMi-lr-li-li-Jr-lr-l rii-H r-l i-3'»1'*^t^'*-^ir2rrTji'^(MG^rHrHrHr-lp-'f-H rlr-t 00 « C"! (j-i t^ iri c; *£ o M ^^ rs i~ T}< -^ CO c^ o in p t- c^ p Ci <» ^ p ift >*'i p rH i^ CO »p -t< I- »p 1- o (Ti /-OWCOGOihcO-iliCCQ^inMe^C^C^CNrHrHC^r-t'rHr-i ' r-l »HiH 0»OiHCir^(Mt-OOf-tOO-*1^0CCl-*liCpCicOp-"pC;ip^f7»'OCS^'^tft»^rH»pr-tC3ipt^'^P'Tll 1- .w c-1 CC (>1 C; Oi 'O 4-1 iT. 1^ «^ CI ^- C-1 00 f>l O •<*« t— C: (>3 r-- C-l O ^ I^ CO CC I~- O OS CO CC rH O Ttl t- CO o O"-C00 30'MC0C:rHO>u0C0C0OO!0irtC0-^OQ-li-tC00^'M'Mr-t^lrHi-l0]C0lH i-trHrii-lrHrH ^-tC5>rtt~-C^'^]'^l':i— tini-Tjl"^CNtNTPTlHCOrH[Nr-tCOC-J(MC^ COCOiHtHCO'M cHrHfH t;9(j 01 9S«4U90J9J Ot-tC-lli5rHCO-^a)rJ'-**^COOiCO'^»^COi-<'MC:COOOO'MifttO'^'*l^UOCOCMOOO rH UO-^iC-*** l-l^-^no51^Tl^ln1<"a.t-l-u^-JrHCO'»i* r-trHOCJC:cca:t-t^Ou^ICCOcoco(^^f^J(^:(^J'^^^ •SlllB9(I IB^Oi in C5 1^ (N I>1 OJ rH rH rH t^ (M o in m t' • t^ ■S.IB9JL 09 o* Se nioi^ OSOCiCOfMCOXOtNCS CO CO (M rH (M OrHinOW X -lO ■8JB9X ge 01 05 tuo.ij rH (M X . in o o c-j c: CO t- o C--3 X •* CO CO CO !M rH Tjl ttl X OC5CO'1<'OOt>-XOrH -O N rHOTH I-IC5 -O •8JB9X 98 01 Qg tno.ij •MB9;£ 08 01 SS lUOJ^ CO to IN . 05 rH 1- -^ CO rH • (N rt* CO •*•* rH IN (N t- < C; CO rH (N to CI CO 4 t-^ 1-i f>t COt^rHin-^rHt^COCTiinClO in CI o CI rH (N -in Cl rH rH C] rH t* • CN •S.IB9X: 55 01 OS wo.i^ M* t^ • ©fl rH CO t^ O'*'*OC]ClrHC0l0rHO -COCaXCSINCl -rH •8XB9^ OS 01 ex raoj^ « O CJ I- rH 00 t^ CO rH ■<* CO.*Cl OinmOi rH rH O -O X )-*rHX -O •OCJCOOi £» .5 f-i"-^ ^J5 '4 i-| 5=1 'l-S ci ? ^ i5 'S..-': 'J ^ S<'COt~t-mOrHt>-t--r>i-IMl-i-IO-iMl-Oi-(CO-HO'*i2t--'-'3!?iS'»'2^ 00 00 lO i ^ ii O -^ 00 CO S^ CO iH (N (M f-H r-( rH rH rH rH i-H ■*i~lOi0005eOrHOOOCOi-H®(N(NCOIN03i-HCOOOl-OODOO-. O05l0000i-I0'><0000!0ffl CiOWS^OOt^uaOCC-^tNCOrHC^C^r ■ cot-OS t-t^«>-i-50c»ot-iot-.oocotatoi;--»>'*'to»io OXf-H^t-l— r-IC/300l— -^O'COOO** COOlCOC^OiCOO&tOTHOOClC.OCSOiOJCOI- 1— 1— l^tMCO'COf-HCO^Ol^-^i-H-^b-O'-ti-HiCOrH-^f-lOCOCO'^CO'^^iOCOCO-^COC^'MCOCOCO OOSO'^CO'^O^COC^tMi-HC-li-li— IrHrHr-tr-t rHi-H tHrH •sssuiij) ]^i; OI^I>- o cs ^ t iCSOCO^OOinCOiOi-H-^COOO'7^l-OiftlOWCOCSt^'>»CO^CCC;45;J« . .. — . -, ._ — — _ . .. ■ ^ ^ ,_( ^ ^^ CQ irt if^ irt CO o *o "^ « CO CO ■OOO'OOT •Bq^saa mox ipocot-Oioci'^i7Hi-»o^t>op'^i7HWi-»pf^'^«wwwp^in-^t— oopi-»p T*(005Tjf«>l'-WOI»iOWOt-oi>«300'lD4j1CO!-HCiOOt»i-H(>l'NC^ ^0-*OrH:OCi'^':OOU^COOir5'^l0^^iOCOCO-^C>J!>4COJC5cy3»riOl-Ci00OrHC0i-<-lil— t^'MOOOOlrt'^'^CO » Oi I- •-"s o >o lO -^ 1-1 c; Ci 'J3 1- 1— o lO ^n, L 1 -11 ^1 Tjl -* -# ■stut'fiQ [i!;ox -tcoo^rHO^Nt-Oijiosiot-oiMcOTfic-. eo-od-*-i'05-t-i2-3;;*co O^i-HM(N-^iH-1iC-li-H:00^t^-1iC0Mi0O«0l— *Op'^pppCp»P'^i7iprHi^'*0O!Z>'«JlC0C^rH OOibo r o4^1C5C500t-00o4ll4hMO-i)r-iTfi'C^C-lC^^OI-'^(>li-«O®CSC000 1-:D^:0^«0'O ■vesO-. COl-I-5D-*-!(i-.Ji-:OcOF-i — ooCi:oco(MOCsOiCOi-t-t— cDOOOmo COC5»t-l-:OCC"*'*'3iCO:OCOCOCOC-)>J'MMC-I3>ICl'MrHrHrHr-ti-( ■paifioads ^ou saSy spjUiVidn sjBaX gj, uiojj •sveaX cj, o^ oi tno.Tj •s.iBaA' oi o:> 59 raoj^ 00 1- t- CO O -O QO 1- ■ O (M • I-H O T G^S-IfHCOrH -1* O CO • 1— t- »H lO 00 COiHi-l-^O '(MCO i-Hi-t ^-oooooooinc^cs -inc^ ■* i-ieouo ■*■* -CI IN sj^a^ 99 o^ 00 uio.i^ COi-t 08 tnoj^ •sjua.C OS o| gt luo.ij •sivai gt o^ Ot WOJJ t- 00 00 05 e-1 -* -- oo iji 1-1 :D!N 1- I^ CO 00 I- 30 1-1 •* -"Ji Td ») CO t- © W T*l CO ai r-t •s.maA" 0^ o^ gg luo.t^ •s.a'9jC gs o* OS iuo.tj CO 00 in CO CO -* CO (M iM CO ea O 1« iH -* CO 00 141 •8.ii!B\ OR (y) gj; nio.tj 1 CO 1-H C» O CO U5 t-H •* I-H 1-1 O 'O 1-1 10 1-0 O CO CO O CJ t>» CO ■ CO ^ • 0 (M iC 0-1 ■ 1-H X I— Tti rH 1-H C5 *4< 05 • 10 1— I . ijlt-ia rH w I-l IN o oq »q ■>* t- 1-1 r-1 » CO O rjl Tjl LC r-00 lo o 00 O » O to iTi • i-H Til 'ii I— -.0 O to -# IN lO lO O »At-0 ' •1-H CO 00 t- CO 00 ■*OS • • 1-1 to CO 00 t- !>. OJC-ICOCN * -t-OOiaWiH tOCOCOCN • frl 10 10 -^ I-H 1-1 tK .0 .'1-1 -■ IN 1-H I- I— X) 1- O: rH IN = — (N 1— lINi-irHi— irHi-il>: O ^ t^ rH 1-H OJ IN -(N -IN t-rH • tOi-H (N •INrH I" •■* C5 CO eJ 1-H IN ■ai CO IN CO uO 1-H iH to to f— 1 CO 1>» 'S* coe^ i-HTH 13 c; MtC .(N lOrH 1-H ©4 ■ rH to CO « to rH "# 1.0 0^ rH to • 1-H lil tH ■* .lOt- PI •« i-H • t- rH rH rH rH CO to 1-H F-CrH .rHIN O -* I- 00 e^ IN IN ;a : £. » _ to £. •73 5|f3 :| : s •.3 tM . 3 : S| -^Ul^'^vjJ^^i^pJO i-^ciM-^iA:or-xciOr-<(Mco'i) cc « e-i w ci os « « o m oo oo n ■ji -f -* V" '.- ?' r".~ f ?' ?' T : ' ? ? V '.' T" ?'.-?' ?^ "P ■??"." T* ?"."? T^ 'p ■?* ^ "p "* ® "^ ^'S ^ ■* ■^ ■^ I " •ooo'ooi .lad a:}Ba ■gllJtiSQ tl!}OX •gasnug III! mOJJ S114B8fI •OOO'OOI S -SldBaQ IBCIOX ' r'a C2 i - c: 71 'M t- :o -S' JO i^ it^ h-it5«0 3:h--x>-tc:"»''*ai-*cOira(NOC-)^ a:iCM00^1^CO^CliiCO^t^ ' OC»C5r-li«3inrHrHa:OCS-^o60i-f»^r-Tt*rHi^ilC; JOtb CO to :0 •-< ■^ •^ '— "^ *^ ■"-"■- —^ -* — ■•*—" — **-••"• — . — ^ ^ . — -- d rl r-C i-H rH CO«:0<-«-.^t^t^iO»ia-^0'*50:£'U5'^-«»'«OCIdCOrHC1*JC4rHr-«Wi-1rHrHrH rH 03i'Ociinr^or:-i*r?c>-HCiC5co-^;ocioccr^rHOOinoci:ooocof>DOc;Lr:);cori-tn^. ^iKr^j-^O'X)-^-*'^ to-m corHcicsMcznoasooiCsoot-wt^oo pppppCIt^'Z)p'^';i«iprHptp'^CIC3-^mpu^ClCliClI->;ZCOrHrHrHtHC5inOX.O:0 71rH '"' 2 ' ■* £ ^ "^ "-^ 5^ '^ ^ '* '^ "* ** *^' "' "•'^ '"* ^ ""^ "^ ^ ^^ '"'^ ^ *"• ""^ '^ '"^ *^ '^ ^ 1'^ '*■" *■' '>^ "-^ ^ ^ "^ '^C;CiOC5t-'^-0-^'*C0 70COCOCQ1 •sinuaa IB^.)X '+<:0i.0-^CI-t^rH?0Orf.iftl-c0CII:-:C'O:0C0C>i-7rH0000^i0C0rHOCSC; C3L«■*CSt- V? •£) O OQ -^ 71 1.0 ■i -* M CO rH r- 1- -o o —■ 3 00 ;o :s CO r- rH rH o r; 00 1- 1- 1- as -o -i -o l^ ■£■ CO 05 CS Ci Ci I- '^ li^ -^ -^ CO 70 CO CO CO CO CI 7J CI CI 71 rH .-I ^ rH r-t rH rH rH 1^ S>-5 c -J; 2^5 » ~ = p 'pagpads !(oa saSy 'sp.ii!Avdii s.reajf gi tuo.i j •s.ivai gi o:} oi taaij -sjBa^ OZ o* S9 ino,i J OT • •* - -rH • -iH •O t* Ci CI CO 1- CO OO CI rH X C3 CI 1- X H" 00 -!• 00 70 O rH rH -J4 CI CI -!)< -^ O 1-0 -a O CO 00 rt» rH t- • -* CO • OO 'i^ O rH 70 -r-l • CO rH :0 ■ CO ■* O rH -^ o • rH COrH rj< • O rH rH I- rH CI CO ■ • rH d CI m 00 O r- d CI ■* 10 ■ rH rH O CO Tji «# rH o la rH CI y^l V:> t^^H-^ '&ve9& S9 o:> 09 nio.ij Cl M O 00 S)"0O in -O CO rH -- CO CO •s.i'BajC 09 o^ gg iuo.ij ■eaea.C gg o% oS roo.i^ ■MBa.C OS o; qf mo.i^ •ai«aX gi^ cvj o^ rao.i£ -C 70 -J 71 O » ^ C-. 1- rH CO CI O -1< uo S-, CI CI — r - o CI I^ Cl O rH 10 CO 1- w C-. S O I^ CO 0:0 1-rH ■* rH CI 1- rH O O ■* rH >n cioo ' eooio OS -* rH * CO rH O t- Cl rH jb- ;d --< in ■■O ■ 53 -* 05 CI o m rH • CO d rHC) t- • to •^ C5 O 00 CO in - CO d t^ ci CO CO • d rH rH ooOrHt^ -coco-^omo CO - 1-) d ci CO CO m t- • • !-!>. -^ -^ d •O C: rH rHd 1 O • rH d •s.i«a.f 0^ 0% gg rao.i^ O d ■ n-i< ^-c t^ CO -^ rH rH GO rH • 00 tOd • d ^ 4{ I •s.itja.f gg o; 08 "loij I- rH 00 -* rH t- 35 '-0 CI CO in d * m •gjna^f 08 01 gs raoj^ 0. ci CO Ci 70 in CO (in • 00 • CO t^ «# rH Hi< rH i 5 ~ - a e •8.1B9.C gg o^ OS vao.i^ •axeaS o? o* SI rao.ij m t- rH C5 Cl O O COCOrHCO - !>. CO CO r-t t^ in • -*oo-* ■^d CO coco • d • O CO I- C3 rH • rH rH in d -If CO -rH eocoO!C5deo • rn rn O -* CI C: rH t O'j'co'* -t-ojcoddinrHcod •siBa^ gX 01 01 luo.ij •sacaX 01 o^ e rao.i j^ Cl rH Cl CD • 00 C •rHrHCS t-COCOdrH rH CI CO rl< d CO -11 rH Cl t~* CO rH • O Cl CO CO O 1- dl- CO c 77t- -!j4 d CO d • CO CO ■s.rBa.C g .Tapnfi » o m CO Cl « CO ■ CO I- o d CO CO rH O -1" GO ■■ ■" CI 00 CO rH Cl rH-14X)C5ClCOCirHrHeOCOd -COOt^rHCO • -rHOOCSCOrHrHTOXrH CI ^ 1-t r-* r~t t:^ '-/:> CO CO • -H rn j~t Ci ' • ^ Cl m -* CI . ^- -^ f 'i " 5 2 •.\;!1B»BJ JO jap.10 rH Cl 70 -* lO CO I- Z3 -" O — 71 CO -Ji in CO I - GO 01 O rH Cl CO -I* in CO I - CC C. O rH Cl CO -H in CO I r CO c. ^ ;:; rH Ah ^ rH rH rH rH rH rH Cl Cl Cl Cl Cl CI d Cl CI Cl 70 c; :7 77 7C 75 77 CO CO CO ■ 1 LfT" 420 •sesiiug we t- O 'O OQ i O '^ i^ ^ ^" '?^ ^1 ^' '"''"' ^ ^ ^' '"' "^ ■"• '"' '-* 'OOO'OOT .led a^^y^ ir: CO '.c r-- c: ir: o ci c. 'C ^ i^ f' *-" f^ •* o I— - — o 00 00 w o r*- !^ 5S I - ct c: -^ 1^ "^ I - -^ 7- 1, ir: o C-- 1- i 00 -Jt i- ■— 1^ w c: -M i^ X _ _ _ C:l— — O;i"-00C^wC^'*C':CN'N'71r— iOJt— ICli— •r-Hr— 1— (i-Hf-" I— ) Oi-'-^'Mc-ooo-r'-roin'M^rMcoCiOt-.'-'Cr-^Of-ici •stn^sa T^^OX ic 1-t O c-j CO vr: 1-" I-- C>t w r- O I!:: I- 50 CC C: CM r-i C: G-u:30i"*'*0i00Oin® ■ooo'ooi cccococi-^O^r-icOC: 1 c*. c-i « c. r- c: — ^ o c<5 GO »-• CO CO c; (M o o CO c: 'to ic cs •* < ic f^i o i-H -^ — c» 'o r. ot -^ o p o. c>: o; X -Jt »^- r- t^ Tj« -^ r^- OT 'O <— -C^ 1-- — C-l GO W c: I* w w ^* »- u- 117 "M ^ *' *' "' ■■ -M r- T-H 1-1 rH ICOCMC-lCCCOCCi— iCOi-Hi-lrHi-lr-tr-'f •sqjtjoa T^>0X c: '-o c; cc ir: C-. ;;; ■* c. CO r: o X c. -c o 1 - c ;T-l'MQ0050l"-r-tCO'»*'0 t-- O OQ ■* i o X !0 o 05 "O o; u^ CO X -^ -^ '^^ Oi CO oc !_■- -* -* 1(^--OT7HC^ n'^t( IO-l(M'Mi-HrHrHr-«rHr--i-tr-.rHr- 5 •IS •S S JJ o^ E •?• ■" C 'S -" 5 ~ o Si"" 2 s s •Sa § « -9 ^ S--2 |«^ sis 1 2 ^ *» S ♦* ** 2 a a»~ - v « 5i •« •« -» ^ ^ * s ' S.-2 5 o* s s > o o u o X t 2 ID fill n o 30 io -i -Is -in T- ;'•; 71 ■>] fi -ji rii^ rt rt 1^ 1^ Ah ■M p TO o^rt■:r•i^-/2co'M-•■/5yD'M>5-.^|-1'l-t-^l-■^o^-1'p^-opippecooTOl-^-pl-«« w 1^ -J; 30 -j M -i .!< f 1 i -i -i .'r: -^ ,!< b t- 1^ ■* 'jj l'9.f qi rao.t J «- : iH rH : - : es : : !- -M .- 1-1 >-<:::::: TO :. rH :: (N : iQ .:::::::: : c 1~t ■SsiBa.f Qi o^ 01 'UO.I J ^' : i-' ; :^'S ;- = o::u-:::.:::(M::«;:::rH:::r-i:-<:.i-i: 3 ■saB9,f Oi o% 59 uiaij I*- N iH -o : : ffj o : r- 51 o : tH 00 : ^ : : rn : -m : : ; tj ; to 1-1 ih : : : : to : 1-1 to : 00 ■sivsigQ 0% 09 tnojj co o o t- ^ -;• -o : 1- 1" -5< : to ci : .-1 : : ; : 'i ?i : to r-i to to t^i -* .- : : ; : : : ti : iH ■s.iBaiCo9 ■•o.-i :-^^ : :TO30rH :.-.ooriinTOiNiNr^ : : : -^ —1 ^ ■>■> r^ i ■8.iBaX s^ o^ Of nio.i^ in rH M C5 3 ; -M -o : 30 IN TO iM « : 1-1 »! : : r- : ■>] : I- : : 1- as to rn t^ i- 1- rn » to ; -o e^ : : :o 71 « : ri to •s.iBajC 0* o; SS «io.i^ »i .* i-i TO : rH (N : : TO 11 p : -M (M : — --»»] : ;s .h .ra to 1-1 to e-i e-i : ; ; -m i-i : ih •s.iB8iC SS 0% OS tuoa J -o -* -i 1-1 ri . i« -o : Ti O O O ■* . -M f-l - i-l :m — 0-.0 : ri ■«•*?) 5j ; ii « 1- 1-1 to ^ ^ (m »» 1-1 ; : : 1-1 -mo 1 •SJB9.f 08! r- -o — i.-; -■; M n ■ -»• O 1- X TO rH . -?i . -M TO ;Oi-l;^-)i ;'>lt^TOlOTOn ; IldMl^-^m-^TO-Ml-fN : r^TOf-iTO p •8.1B9.C o^; 0% ox nio.ij ■8aB3.f m o:> 01 U10.I J : -f ^^i-i :-.s-i<^i-TOt-('Mi-ii-ifhi-ito :^ic:if:-.scoi-i cto^h-mio •a o -J TO •* : : i-i -< : ; -*! .-1 : ; TO L'O n to : : ^ ; ; ; : pH ; ; . (M ; :r^ ; ; -M ; -M ■S.IB3X OX o* S raoij 00 TO jO m -* 1-1 TO 1- : n -M .» CC K K 7J »J 71 ei (M .- ..^ r-i i-l fH 1-1 rH rH r^ 1-1 Ii c-. 1 C)ir5iC'^'^tr-< i •paijpgds ?o(i sa3y T*- -^ *0 • • CO (M • 71r^r-l ;r-l ; ; -r-lr-i-* .71r-rH • • • '->'-> ; ; ; \ '-< \ ; ; ; CO •sp-n-Av -du s.rea.f c^ uto.t^ r-( rH • M • Jt^ ; : CO-^O -71 • • • - ;71 -COr-ieOr-l ■ • ; ; | ;i-l ; ;tH^^ :«:::::-: ;-'> s.reaicg 0^ 09«io.id •s.rea a" 09 01 gg iHo.i_j ■s-reaX og 0^ OS uio.ij CD X T-H • "MO ■ •^C-. '^ -m . . - r-171 -r-XTl -OOr-l .i-HTl -rl . .|-|.* 71 C: C. 0; '^^ -M ; (?i » • ^ -w 71 IX, -71 • .* I- • 71 .-•: X rH 1- i-l ■ .0 • rH • . CO rr - r-H ... •rHrH s s-a-aA" 05 "% CI uio-J^ OT X M rH 71 mm . .-).1^IM»X71 .71C0C0rHX71711-OT -r-tn ■ .00 . - . .^1 .... .71rH X C7CDOO .rHi«COr-( .rH . g -aniav ot en g mo.ij t-..c05^in7i7a-'j<.*in rH 00 . . 71 71 71 m 1- . . ■ OJ - . ■ • ■_ •-! ■ • Ot rH . . . • • ■ ■ 1 71 -S.I lia.C g .lapufi i-< c; I- -^^ CO :5 in r-( .c c « 71 a a -* CO 5C ry Ml :o CO r-l r- ,-< ~r - s .- 0: -t- X -- .n - • ;; - - 71 71 1- r-4 - = X X rH tc T(- X - 71 r- r- C ..-^ Hf .» . - 71 - - i-H rH ■ 71 r^ 71 71 ?,S'- a < u Q b. U < Diavrhoia and Dysentery . . Phthisis Typhoid and Simple Fever . . Accidents Atrophy, Debility, and Inanition . Convulsions Disejises of Circulatory .System Pneumonia Croup and Diphtheria Teething Lung Disease, &c Bronchitis f>l.l Age Premature Birth Liver Disease, kc. TuVierculosis and Scrofula . . Enteritis Tabes jMesenterira Cephalitis Disease of Stomach Alcoholism Chilbirth and .Metria Brain Di.sease, A:c. Apoplexy Cancer Peritonitis Paralysis, rH 71 o:-t.m:c I- xc^CrH 71 co-.j' in ^ot'-x^CrH 71 co^vncot-* ^"-. , , . PRESIDKNTS ADDRESS — SECTION OF HYGIENE. 423 s ^ ■^1 c d 5 s 8 rt » p — •2 psgioads ■jon saSv 09 '.~ ^^ ^~ ?''.- s' ?' V' ?' T** T' r^ r^ ?■' ^^ ¥>':'' t' ?'?' 'T' ? P ??■• ?3 V" "i"" ^ ? '^ ?':'''? "P '*''' ^ "* Ci GC I^ 1- O O O Ct j^ C-I C-l C>) C-] IH rH F-( ! O "» 2; n L- y; o C! Ol 35 CO I - I- 1^ « W5 >» IS ■.-; -* T(< »)< -t" O 50 CO eO eO M « «■! ©1 !M 'M M »1 <>) •-i ■S Zi ^ '^" - ''■^ '^ "•I '^ CO ^ c: a r^^ i>i r-> c: '!i '>i <^ 0-i r^ ao ^ <:> m -* i-i t~. t~. t~ f n o a a-. t~ t~ t~ *2S??5'^^^-C50ooMcoc^i-tOociCst^i>-t^i-:s:ou;oo^^'^coM«cocowcoc'ic^ic-ic^ ■gpjV.M -(In sjsa.C gi too.ij •saBS.C gi j <0 o cj ^ V. I •s.rea^ Sf o^ Of raoj j ' sxeoi ot o* 5S rao.i^ ■sreai gg o!> og rao.i j ~ -i 'MBai OS o* So nio.t^ 2 O ~ •sjBa.C cj o'j 03 luo.i J •S.IB8.C Oo o* ex rao.i^ -tj-reaiC sx o^. 01 tao.ij cooi-i'* :0m : :e<3 ciNm : ioomi-i-i^ ; : :i-i(M»tCr-i : : ; la CO C-] rH : c^ i-t :co :i-i r- N 00 0-* ooo l-C« 1-1 l-H :co :c^co:ccc?oc^!M ; ;Or-io*:coc^ :rHr-» : ;^oo :co ;c^ OOOOOOt- :] :coi-(i-t(Moo :co los ;(N-* ■*;0!M iq p ICO :r-icoojr; :i-"-* roco-*'*^ rt ricsinoo^iM:'-!.. ri I-I. I-I •• CO (M ir: GO - 1-1 .1-1 . . .CO i-* • •rHrHL^t-i-ICOCO :OC-)COl-:OrHiH !^ u %} s "3 ~ •siBa^C ox 0% g inoj j •s.ti!aX c .lapufj •Xiip^M JO J3l«0 CO r-llO CO : cooiM -* : CO 1-1 . :'* : :(Mt-ii-i CO 1-1 IN 13 I* ) rH : '^ i i^ :s-i CO : rH o : :.^ s: •S f '« S 5 § <= ^' (^ £>« o ;:i K tt 2 S 5: w"^. « o 3 K-g ■pagpads ^on seSy ■spjt'.M -(In sivaA cj, mo.i^ CO ci t' 1^ -^ 1;* P T'l p 9"- 7^ 73 1- *?' 7^ 7^ i^ i' "p "P »p 7^ th rH o Ci 03 Oi t' :o ^ o lO -^ Tj< -^ CO CQ CO ^ -C50'?lCOOOOf-tC300i5^r-ICO(MCOC-lNi-ICOC03;t'?0'^0.-ICJCCt>-(Mr-tC3l^^-tOO 'MOO'Mt^iO'M'MOOiCOOCOCOOOOOOaCt^t-l^;Oi/5lO'q<"^'^Tj100COC^5^MWNfHi-HrHr-ii-( sneai qi 0% Oi nioj^ •S.1B8^ Oi O^ 99 1101^ •sjng^gg o? 09 tnoj^ gJBai 09 o* SS nioj^ BJB8jf 5Q 0% OS nioij S.IB8A OS <'* St UIOJ J •sjiia^ St oj Of tuojjj si'Ea^ Ot o* S8 raoj^ ■sjBsXgg o^ OS nioj^i sj«9A OS o^ 55 moj^ 8J«9jC sS o^ OS uioi J siB3.Co5 o^Siraoi^ •s.maif gx o^ oi i«OJ^ •eivaX 01 0} s mo.ij ■s.iBaA' g aapiifi (N •♦ I-l O O T5 --O O CO r-H . -* :0 -* O ■* (Mc^oinocDoio ■*T-ie0030 r- ■* 5^ CO i-l !M . M CO CO ■ ■ C-l ■ CC "^ • • rH r: ^ CO ^1 <0 • O C5 CO O • MOO -OJ 1-1 cocoes ■ la CO ■* t- 1-H • ■>»< .-^co S^ -7-1 ■•*^ -to • -(N -OOO C5 -J> M lis . . CS rl •* so • •■-li>. O -1-1 -CiO 'Oi • •■^i ■ ira ■ r-l -^ • H • -1-1 CO ■•-H • o^ I-. ffj (N tH • ao -co • "O • 1-t T-t • 'M • • IM -^r-KO •CO .000 « 10 rH rH f-( ffj iH 0-1 00 • O O ■* lO CO • CO C-l CO f Ifl rl . • W • n CO • • 1-4 w i-t CO e^ CO O • rH rH pH m • CI 5-1 ■>! -o rH CJ • CO rH . rH SO C^ T-H T-H ifl* • « • tM C3 ^3 ^ W . rH QO00 rH rH CO rH rH •CO t-.rHCOrH r-i»>elMr<'MCO?5«COCOWMCOCOCO-3< PRESIDENTS ADDRESS — SECTION OP HYGIENE. 425 « 3 ;S^ 0) ss §S g-e iio ks S c> ■"• m n 3 H o . . . ^ ^ T*^ *.' ?' ? o p iQ *>! c^ t-^ o go '^ •p lo -^ CO eo "j-i CO CO t^ I- :o lo ^ ■* -^ -^ -^ n* '^ ?5 w CO ) -^ CO rt ?^ ?0 -T-l O Ci 'O « •pagjoatls ^ou saSy -dn sj«ai g^ rao.i^ SXB9A e^ o^ oi lIIOJjJ r: ^ ':^ Ti" '^ '^ c-. ^ y^ t^ ■« 1^ ■^ ryi r^ o ifi f-i a> ■£> -f a t~ -r ^ w^ i~ -^ n vo •)< ^■• P V" '.^ r* ?^ *.^ T** ?5 CO c:) -C^ rH O f>I t^ ip p OQ I- rH '?) to -^ CO O O 1 ' — * CO Cl ^ ^ p O M o ^ o o 5£ S S .■* i" U ? %5 9 ? !2 i; ^ ^ '-'*'''' i °~- ^ ii '- i 'i^ "=5 o ^ M o) i o i o o ih ^ 126;feS3l£:2S^'^;S'''S'="»^c>(N•*(NOooinoJoeo'^^0!0^0'^^»ooa)xz>^-ffllOco^5 C5 r-( • ifi O O .CO CD .7^ 3» CO O ^•5-* . .rt . -r-lff^CCrH •Tqfi': i •8ji!3^ Qi 0% so niOJ J "M GO • ■r^S'l • CO C'l l-H . f-l PN -M ^ ^ I -sjBaA" 59 0} 09 moj j I O ■» t- 1.-5 O . lO CS -^ . • rM CO rH CO 5^ ■* OT (O -M 1-1 Ci . OJ CO O . . fH (N • ■ CO r-t a 5 ;saB8.fSQo?0S inojj = S s ■9iv.aA sf o^ Of mojiji i-t CO . . ^1 (M . . rH rH C<) C-1 CO C^ • ■ i-l rH 00 O W ■* • Ci CO rH !>. -^ lO (M ©1 rH . CO lO • f-t W Tjl W 1-1 *S fTi 'CO -CO ■ ^1 ri 1^ O O) ■* ■ I-l CO • M O'l rH ^4? a ji -o -;£S S 3 .i .^ ^ i Cs-« S U - j; S IM s =<^, -> 1^ = IS 8 •!s^ e « Q s"^? :^^|? j<^-M : »■•« ; «i ~ : 5 C -35 W«9XcgO(J08 wo-i,t[ 1-1 O i-H 1~ ■ O • t- • i-l 00 Ci >n ■ 1-1 rH n iH rH rl« , J -i = s a '■§ ° :-^ rHMSOHj4if3;Ob-WCSOrH'NCO-**UO'.Ot-OOC50rH'NCO-*JOJ»«ri(M'MTl»JI'JCOCOCOrCr0r5?3«COCO'J< 426 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. '*~.'^ V 12 ss o a co Q^^ "3 (_, e;*§ •-> 2 H O 5 2 i •p9gio8(Is 30U saSy =0 ,C •SpjBAl -dn s.nis\ ql raojj •S '^ "^ •2 I 2 = •sxvsi gi 0% oi tuo.T^ ■SJBei Oi 0% 99 rao.T J •s-rea^C 59 o(j 09 moj^ •B.IB9.C 09 o:j eg uioj^ •S.1B9A ug o^ OS KIO.TJ 0-*in»C5t-l-'5 0000tOOO»(MOOi-IOJOr-IC:0-*r-05e:'*MO-ii--:-]rHiriM:0i^ir:iHO f-tT-l(NC. CC'tCO 'Oi in • r: o »c »£5 o • t— i-lrHIMO'^O'. CO -O • rH -O ■* . ■<* C5 CO M ■ Tj- in l^ 'CO •s.n!9i OS oj gf- iuo.t^ ■i) ] -siTja^ gf c). Of- rao.ijj •s.iV9^0t 0% gs luo.ijj ■8.I'B9jf gg O'i OS lUOJ^J •s.t«9;C OS 0% 55 raoj^ •s.ii;9,C gz 0% Oo wio.i j •g.reaX 05 01 51 ino.i^ ■S.1138A' gx o; 01 nuuj ■S.lB9,f 01 O'J S WO.IJ •8JB9A g .lapnQ I i-l -* • to o o < i-l(N ■ r-l 1-1 • in « CO • O M CO -IN (N .CO -T* 0!->* • iH rH 10 ■ r-l inc-ici .^--^o pHi-Hj-fH -Oi o -c^ .ir;(Mm(N • •GO'-i ■'^1 • c: 00 -* • ■ f-H Ci . 'CO ■ !M C5 (M rH (N CO 1- ^ . Tj» • to C» CO CO W IM CO . . (M « i-H 00 t-» ■ -e^ . CO -rH r1 .1-1 fH • OJ ^ &1 rH (M .■^COrHiCCOCOr-tO^r-t rH "I-lincOrHCO 'CO .rH •CO ■ r-l r" ) fH -^ C-1 I-) -^Jl r i-l CO 00 CO ■ « CO (M 00 CO ■* IN -* COI^OlCOCO'^WfHC^ i-lC-liO -iMcOeOCO -INr-li-l ^ -* . . CO r-t OI CO CO CO c^ cq c-i c-i IM rH f-l • rH • rH IN IM • N .(N ••-< t-l -IN C;oi^ .COCOt-OOOiMrHrHC:OCO'*C:OtCI— rHrJ'C^tO O— • '*a;i'r-GOrH Z- '-^ C C llaf s ill ||_i' ^ — , o ^ i-^ -.* n" ,-'. -^ ■". rCl '''1 :_ r£: -t; (^ .r. ■'^ ^. -A »y« «' ^i^ _:- — , , — f« - 7: rv! ".7; fi^ r^ ir^ /-I -^ Ch3QOP-1Ph':J — i^UJ'Jt^WlSPu, ?cos33 0h!« .- ...... .~n.n ^IMe0^in0 1-000»OrHWCO"*OtOl-OOC50'-'IM«»Kio0 1-00030rH03CO-*mt0 1-OOSt A^TJVJ'BjJ JO I9p.tO r^ "-■' ^ •— r«rHrHrHrHrHrHrHrHrH(M01IMO-llNIM(NIM(M! C-l 1-1 rH O O-. C. X CC & (K O « O O O i-'5 O lO O t~ »r r-(it: ■.- c: r-i is V o « r-i 1 - c: r- -c ■* r (M o c-i T^ cs o w c^ *>! o i-t c-i -i to "c o 'o i^ o: "I* -^ w cc CO ^1 «-< »-* L*: i~- o o CO 00 r-t rH r: r— Oi t-H CO .^ S ih f- M r- -5 X ci 5 oi '>! 5 o i~ r; ■;)• o '>) K '^l p 1,- in "N M « o X lO i-T « ^ ; cc i-i «1 I- lO Tt ^ O^ - OO M rH CC t- C; ■^* t- ^ fM t'- O (M r: C-l u- Tf -M I- r- O C I- t- 00 00 "i^ "S Ift CO fM I-' o .,, .-oc:c;c;i-«0'<*'r«'c«?rHOCiCscct'-i— w«ooir:ir:0'f'*'TMcocococoo^cccoco MeJ5^»Jr-* rH Tji i"^ 05 t-M vnrfOrH : :o ; :"-oi- :rH uoc/rr rH". COrHCN . . i-^ . . ^ r^ . rn : tS CO : : ; : -rj* rH rH '^ CO CO rH -o» :i-i^c-. (M : :o ; cc -^ : : CO :!M cts-* : : : rn -^ rn :tj«coco: CO o i-iN c: T-H oi : :'M rHrH CO rH rH . . IN : ; : '« ; ■* c: co ] • 'Oi • ' •(»'*0-lS;CCrH©1lO ;C0 ;O0t-COrH .rnCCl^tNIMrHIMIMCq ;rH COCO CO cq : : CO '■ ' 'i-i . . • OI O rH -r rH uO : : . ■* I- X oi o : CO IM : to : ;; c: : o t- ■* o IN IM oi : : 90 : O ■* (M rH • : I - J- «0 «C rH : O ■coco ;0>]Ol-^r-»rH 0-1 rHrHrJ* ; ; ^i^rHI^OrHIM ;iaTK I'^OrHIMCOlM :C0 (M c; : oi c: : ^ l-'^rHCOfMrH :rHTt1 ;C-1 ■* O I'M 3D : rH : (M rH : CO -C I- i-O rH 01 ■* : Ol Ol : O : r» Ol ; OI rn ; (M Ol Ol •WB9.f OX Oi g UI0.1 J 35 :'#05 0j ; to^oio : :rHco — c/:r- ■*iM : f-i ■IrH ro^^l- ;COrHIM ; : r^ t-^irt rH Ci C'J rH M •■* OI rH (M rH rH QO rH CO l^ I- ; r- rH CO K> rH IS CO ; CO : C; r- -* in (M :■* ; rn rn rn CO CO CO ■Ot-t-OlSSJ^aOOr-CrH-H rH c: ^ -H c: -c y. c: o c » ■'tcrOlClrH ; ;^OTj*rH ; :C0 "XjtrBiBj JO JapJO i'S -^ : : J So ? . >.- : .O 3, ^ - K £ !— •? » ^ o -r X r. 1» -r-2 5 = )&- — <»HO'l"lO«t-.COOSOr-"01COH>'in»I- S)" S D Or4.- O rH -o :3 I - CO p c- s;:;sssp;Si::»aM5ojoii;.o5iMMo5«co5o=o I « •* 1.0 C 1- c ! coco CO M CO C 428 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. ^1 ^ ^ O B ^ - C8 S S •psgioscis !jon saSy^ CO t* -O ti •* ' lClT)(NIMMi-lr-0 00'»-l^i-Hf-<005XI-1^00ir5 0'^'^-*COCOCOCOCOCCC^C^C^ iO'» -iO s.it!a.C OS o? St raoja {- OrH CO 00(M ■ CO CO *« rH • lO CO O lO lO IC CO -* •* CO rH . IM • CO ■* US'* OO N P ^ H. si-ea£ Of 0% S8 nioj^: 00 t* OS rH to 03 (M .O I- • ^ O CO X o sjBSif gg o^ 08 raojj rH O t* t^ 00 -H C^ • -^ 1- CO rH rH sdV9£ OS ^ •B.iija.{oi 0% S moaj ■* 00 05 (N » H ■ • » -CO • lO • 00 TJ 'T^ rH ■CO . ?C C- rH •* C-l ^1 Ol 0-1 . CO -* ■ C^ ■ eoo .00 •moe^ •meo'MH)' •■*■* .n •0(M -co -OOeOCMrH --"SI -0-1 •-J'tO •50(N ■ r^ •in'*rHCO1 • t- . OJ rH rH •<*< Oa rH to COCO • Ol rH in -IMiaiO -rHiHrHHil ■ r^ •COO: •RaBaA g .lapnfj ■£mv%is^ JO japjQ ■^inXr^tOXOJC; -OI -co •ClTlHCOrHX'MrHl^OOCOCOaSrH . •oovoMHticieos^ rH00rHC0O'-O-O(N •« -in -O rH rH-*OCOCO^-*^»ft • ' r-i r-i CO rH (N rH M ••a • a ^ i^ ^ :|^ ti-a -= O 5 sa S3 tfl >. ■^ Is ~ ^ ^; g'4 ;^ Oh ^ ID " * ■? '-S g 3 '3 iS 3 =; '3 -^ o i? . S to tl) c s'5, ;2-s •r" 3 2 i Is -^r;*-M rt s - o ^ ^ aajjs — -^ a5HOHa2ffii»;:MwysaHa< lHe'ie0^lO!0«-COa©r"NCO-*10(ei-'/!050rH(MCOHflU5-0 1-OOCSOrHOJCO-»'OOI-00»© lO^C^C^fMOlW^M'MCOCOCOCOCOCOCOCOCOCO^ president's address^section of hygiene. 42& O C4 Eh « Q •psgioacTs ?oti BsSy •Sp.ITJ.U -dn sivoi qi mat j 8.reaiQi o^ Oi raaij o iffl c; M 00 c; ~. C r~ I— y: -»• cc ..- o •-: c I - -f "-I •* "♦ 1- t- "■3 f- -* 5^ '" o I- CJ ■* OS o> o: 3; (N iM iM ccco^•^o•iJ44t'Mr?<^^•^l^(^^'fl'^l4■J^lr-lr-t■— •-HrHi^i-ii-- 1- CD C3 !3 i—i l>- ©I l~» *-0 "T rr it i-< I - M d t^ r- C ^ "^ O C^ C-l ^1* CO r- »rt »o (N i—t CO M M CCOOl-»tClC'*«CCMCCC^^(MC^C^(Mr^'-trHr- "M r- O ■ eO ■ • • ■* i-l ■ • e<5 rH •■* rH • • -co !N - " a •^ •ii, s s ■-. •«.ib3jC eg (X) 09 niojj • GO (M I- t- 00(MOOO-*rHt^ »H ir3 p-t rH (M rHiOi-HlCC 010 • t:~ C5 • • CO Ol ■ O rH !>. CO • i. i a* -e ^ tts « S ««. h Ci '^ M >J| V on 00 *** ^ s ffl C eS ft 3 s 2 s 3 « c cs K "^-g" L-:) t- /■• ^ lO *»*< Tt^ M C^ i^'S "M >1 C4 -71 ^1 C^ r-t r-t rH i-l rH rH (M i-t lO C> L-r T» O -^ u- r-l I- -* O f-H r-i O M T— I X CO t^ CJ :0 O -^ CO C-J -M C-1 T— I rH o CS CC CO X t^ I- O CO O in -* (M rl C: CO 1- O -^ O in L.-5 u'i ^ >J< (?■: r7 7-1 !N CI 5-1 r-. rM rl I- 1-1 f-. rl rH r-l r-1 M t-1 r-l tH — & o s « « « O ^ !J s " « *. ? ^ eJ Ji ?^ oj a Vl i. =- <^ ^ S ^ d '-^ '^ ■pagpgds %ou. saSv •Sp.lBAl -dn sxvaS gj, aiojj; •s.reai ai o; oi, mo.! j^ •sjvaX 01 0% gg lucij; •sjBa.C 59 o; 09 ino.i^ s.rB8X 09 0% gg rao.i^ •S.IB8.C ge 0% og tuoi j sjtiajf OS o? g^ luoj^ ■SJV9S gf 0% Of tnojj •s.ic8jC Of o^ eg raoj^j s.re8<( gs O!) 08 i«o.i^ 1— J • M • (J. 1 in ii • . c; I- inC5 • ■rHCO'M *C0 • -X^ -(M iininrHco • ■c:^oco • r~t ?1 IN rH -rH U^ i-H • 1-1 (N i-< iM 1-1 s^ rs T • CO moi-i iH CO - Q^ • r-t rH • ©1 (M CI . Tj( TJ (N . (N « iH • iH 1-1 (N ■ OI ■* -(M • -iH ■* CJ (N rH 1-1 tH iH -IN . rH Mi-H • 1-1 rH -iH r •f-l rl . .(N ■ r-t'li'M'^fSOl^lO -0OCOl-tlflOl(N •i-lrHX^GCiHi-i •rHiniHI^ • -i-l r-4rMi**I-l'M •!— lira WrH • COi-tC • to rH ■* •>* .^r^ '^'iimm JO wp'O •2 iS : o fl) a? « o5S . 2 = ; i2 a ! «> S sJk'S „ 3 rt 3 ■ = -43 Sf S -.^ :« -2 5 >-.. r ?. 55?:i'"i 2- -S rH(MC01-a)OOrH(MeO'fl.r1lneO •(N(N(>J . ■ .Wi-I . . .r-l .e-Ji-IC^e-l .rH .11 • . . o •-" -i-l . . • . . -sjuaX og 0% gf mojj •OCi •CC»-*i-.f'MNCO'.*CO 'ClrH .rH -W— ^ . .|-lrH .©JC-l • t-* -iHr-trH f-ti-( •RH!9,C gt o:j 01" nioj J •OOOf-c-.i-Hff^tJ.M FH...(M.rH...rt.r-l..r^ -sjiiaX 0* 0^ gs tncT J _.-J.eO.--.r-lr-ieOi-<;;r-l;;;-i-li-l.-i-l..|-i............,_(rH!o -sjcaX se 0% 08 tnaTj •0?3 • .»! ..*,HrH • • .CO • -FHINtHIN . i-l . . . ■-( r-l . rH . . r-l . . • - ^ - . . . C^ .• . ... .. , ... . .. .... ... •B.reaiC g 2 -w V ^ ^ c ^ ^ B C^ r^ s; «J r^ Oh a, ^ Uh'C ^'^' 5J s •=> « c = ■Sj <^s s ^ '^ c-i is ^ O' ~ s _ a, sivsA OS o'J St rao.ij s.iBa;C gf. o^ Of "lo.i^ aiBajf gg o^ oS «io.t^ SJB3JC 08 o; SS rao.i^ fi^Ba^ gg Oi OS iMO.T J B-njaX OS Oi gx wio.i^ii g.iBaX gx Oi 01 rao.x^ •s.iB3i£ 01 Oi g rao.15 •s.TBaA g .lapufi ._, : :^ ••::•.::•: : « u^ •* : 1-1 . ■* Cl t- (N as r-l . .f^ : -n :t~r- :co : i'^ : i : i'^ : S'l i-i :»-H ':^ i S3 M 10 gg3'^' : ; C-l -^ CO 0:) Oi :e-j 1-1 ■:s :« 5-1 :,-^ ri-i IN : : :WMcpi^(WO^^g5f7H-^rj<'^ t^OOCa30I-t-OiO-*-*WMOT- JCOIN-^fHOCOr-tC^W :vft :!NiC : :i— I :rH(NrHf-l :C^ ;i-t ; ;r-l ; : ; : CO Lo ; fji I-H c-l IN o CO o c^j IN M : IN . IN -* : ; r-l : cN : ; : fh : ; ; c^ ; ih : ; ; : ^ 00 ; iH N 10 lo CO CO r-» rH ; ; : : CO w ; :t-t :(Nr-t-«** : -^ r^ :::::::; i-^o : :iN :coiMiN :(n : ; :rH rrnm :(n : : :rHrH :rH :r-i : ; ; ; ; . ; y-Or-* : :r-lrHr-li-HlN .CO-*rH ; r-\ ; Ol ; 1 1-^ iH iCN^l ; • r-* z ; ; : ; ; ; If* :>ne'5 : : :rH«3inr-irHcorH : : ; :(nin :r-i ; ;i-ir-ir-i :r-4 : :rH ; : : : • ; r-l rH « rH rH •* M ;eOrH rH ;00(N : .COrHinin :rHINr^lN :"* « : IN . IN rH rH rH IN - rH rH rH « r-< ; 1 i i- : i^ : rH ; rH C-l rH ;eo : : i- : 1-1 r-t : rH 18 ; ~ CO T-i '.r-itr* ; : :rH •* M i-^-^^ i ; :- :iN :COrH i^ : i i : i^ IN rH T-i S :CO itSrH : IN rH rHS^ : :eorH rH : :rHOrH :) -(Mr-trH- (^ _ __ ifillTJ^^a JO J9P-«0 OOPh : Ct, ^ -- ^ ' * -^ .« 5 i2 a! ►< "« Q 'S S -ffl 3 9:/,== S -'•" o ' o o S .=: a i- o rt y 3+^tH-r.ucc4^^t'^!-'OiHc2;Hr<.;:.f-'^3S4>y:.i:HciS^a) j-i3«p-i1PHOOrHNC0'^l0C0t^C0CiOrHC>lC0-#v0i©r'-XC5OrHC-JrtTjremises are thus guarded until they liave been disinfected, and are declared clean. When an outbreak tln-eatens, an ambulance camp is establislied in an isolated spot, and placed in connection wdth the Health Department by telephone; and patients, with their families, are removed in ambulances, which are driven by the staft' residing tliere, in Quarantine, to one of the wharves. They are transferred tlience to the Quarantine Station, in a launcli specially fitted to carry the sick. Suspicious cases are reported from time to time all the year round, but their number greatly increases as soon as it becomes known that 446 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. small-pox has made its appearance anywhere in Australasia. They arc visited by the Chief Medical Inspector to the Board, who decides Avliether they are cases of small-pox or not, and who at once takes the necessary steps. He reports to the Board, who confirm the action taken, obtains special executive authority for it, and give any further directions wliich may seem necessary. As the authority to administer " The Dairies Supervision Act," the Board has power to declare what are infectious diseases for the purposes of that Act. Cow -keepers, and also the medical attendant, must report any case of the diseases named, which they meet with on dairy premises, to the Board, in writing, under a penalty of £20. Prosecutions against medical practitioners have been instituted under the first-mentioned Act, and fines recovered from them, as well as, in one case, from an unqualified practitioner who liad assumed the functions of medical attendant; but, as in other places where dual notification is the law, no prosecution has yet been undertaken against a lay householder, although in one instance, at all events, there seemed to be sufficient ground to proceed upon. With exception, then (as to diseases) of small-pox, and (as to places) of dairy premises, infectious illness among the resident population is under no sort of supervision or restraint. No hospital regularly admits such cases, or cases of erysipelas, except the Coast Hospital (see Hospital Accommodation). There the Medical Adviser has improvised some accommodation for them, but the total number admitted was, in 1887, only 63. There is a Fraser's Disinfector at the Maritime Quarantine Station, and anotlier at the Coast Hospital. Rarely requests for disinfection are received from the public. They are attended to without cliarge. (For prevalence of the zymotics, see Vital Statistics.) The General Hospital Accommodation foi' Sydney is furnished by 1003 beds, in six institutions; of these, one is strictly self-supporting, one is exclusively supported by the Govern- ment, while the remainder are suppoi'ted by voluntary contributions in part, in part by payments made by the patients, in a further part by subsidies of public monies, and lastly, by payments from the Vote for the Maintenance of Sick Paupers, made at the rate of three shillings a head a day for every destitute patient admitted by direction of tlie Medical Adviser. There is also an institution, not included in the above, which is partly supported by voluntary contributions, and partly subsidised, called the Benevolent Asylum, where from 250 to 300 destitute women are received for lying-in annually. The 1003 beds are assigned as follows : — 758 ar^ for medical and surgical cases in adults ; there are 41 lock-beds (10 female, 34 male); 70 for children, 26 for gy I uecological cases, 75 ophthalmic, 22 for infectious fev'ers (other than tyi)hoid); and there ai-e 8 single bed wards. In the country, the last re])ort of the Inspector of Public Charities (188G) shows that there ai'e 1029 beds distriliuted among sixty-seven small hospitals, and the latter receive from tlie Consolidated Revenue either a grant in aid of their building fund, or else a subsidy equal in amount to the public sub- scriptions raised for building, and thereafter a subsidy equal in amount to tlie sums raised by public subscription to meet current THE PRESENT SANITARY STATE OP NEW SOUTH WALES. 447 expenses. The inspection unci passing of plans for new liospitals is a part of the duty of the jMedical Advisei', preliminary to a subsidy being paid over. f append a table, which shows some details of the Sydney hospitals, including revenue and expenditure, as far as these can be gathered from the ainiual reports for 1887. Admission to hospital is as follows: — The tiualitication for admissiontothe Coast Hospital for the majority, is destitu- tion, this being aGovernment institution for the relief of the destitute sick, but eases of entei-ic and other infectious fevers are admitted from all classes for the sake of isolating them. To St. Vincent's, admission is free, and depends only on the suitability and urgency of the case, but capable patients contribute to their support. To Prince Alfred and Sydney Hospitals, a proportion are admitted free as being urgent cases ; a majority either contribute something towards their cost, or ai'e referred to the Medical Adviser for admission as being destitute, when he pays for their treatment at the rate of three shillings a day. The last mentioned class of patients, however, are expected to apply for admission to the Government Medical Officer for Sydney, who sits daily to give orders for their ti-eatment at the hospital which may seem most suitable. In addition, a large number of chronic cases of illness among the destitute are lodged in the hospital wards of the Asylums for the Infirm and Destitute, which are situated (to the number of four, containing about 2000 inmates), in several situations outside the metropolitan division, and I have not thought it necessary to do more liere than just mention the Lunatic Asylums. The proportion of strictly hospital beds to the estimated population of the metropolitan division is therefore 2-9 per 1000; and, as mentioned elsewhere, in 1887 about 15 '7 of all deaths occurred in them. 448 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA H :z5 o Cd oc v> t^ o ^ ^ O 0^ H r^ •< 2 ft s O K S ■^ S •« o o cc C) rSi Bj-()nojo-o(,j ■pag .lad ()soo iBuuiiv rH CI CO O l^ CO _• t^ .'^ rt C C5 Ut 'iCtllS 9SB.19AV •S!JU9l'}'Bc[-llI JO •ojj jfireo; egi!J9AV •iC^T['(!l.lOI\[ •pa^^toipv S98B0 JO O^ ■spog liooT^ ■spaa JO '0& TOOX f-t O CO o (M CO (M 00 CO &; 0) a o 0} s 1 o o 04 J CI «« -3 3 rl s £ c ■2 O) G 'S r ^■ K o" "^ >-. w fq -p g fa s ■§ ^ :^ a « I ^ P i S S S S oT g 5 -s '-' C) 53 " 7^ S g I f^ 2 o 2 ■* S = ■§ ■§ S s I § 6 o I'S I ■5 oard has no power to remove from the register any name once placed upon it, either in case of death, or for any other reason. Speaking generally, medical men performing public duties are required to be registered in New South Wales ; cases occur, however, in which Coroner's summon unqualified persons to give evidence even when legally qualified practitioners are accessible, and seek to pay the former the statutory fees. Some further remarks on this topic are made in the section on Vital Statistics. The law which regulates the Registration op Births and Deaths was placed on the Statute Book in 1855 ; it has never been amended. Under it, parents (subject to interpretation) are required to give District Registrars information of births within sixty days ; and thereafter, the registration of a bii-th (within the Colony) is not lawful, unless some person present at it, or the parent shall at some time within six inonth.s iG 450 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. next after it, make a solemn declaration regarding it. But in evexy case of the arrival of a child within the Colony under the age of eighteen months, born at sea, or in any place out of the Colony whose parents are about to take up their residence in the Colony, the birth may be registered on a solemn declaration being made by the parent. It is not lawful to register a birth within the Colony after the expiration of six month's, nor one without it after arrival of the child within it. In case of a death, the tenant of the house or place where it occurred shall o-ive the Registrar information within thirty days ; the Registrar must deliver to the undertaker or other person having charge of the funeral, a certificate of registration, and this must be delivered by the undertaker to the minister or ofticiating person who shall be required to bury, &c., the body ; and if any body shall be buried without that certificate, then the ofliciating person, who shall bury or otherwise dispose of it, shall forthwith give notice to the Registrar. In the case of any new-born child or dead body found exposed — in the former case the Constable, in the latter the Coroner, shall give the information to the Registrar. Under Section 6, the Registrar-General may make regulations from time to time to be observed by the District Registrars (see Vital Statistics.) I now approach the last section of this paper — that which deals with the Vital Statistics. of New South Wales. Although this subject naturally comes last, it is by far the most important. Just as one way of testing the degree of civilisation to which nations have attained, is to enquire into the value they set on human life, as witnessed by tlieir laws. So, with some limitations, it may be learned by examining the form of their mortality return.., in what degree that legal or apparent value is based upon observation and reason, and in what it is merely imitative. I have, therefore, devoted a considerable space to describing the manner in which our retunis are made. This is very much the same as in the other provinces, and, perhaps I need not detain you to hear read details, of which the value can only be arrived at after deliljerate study. With your permission, therefore, I shall read only a few remarks on some of the more salient pcjints ; first of all obserA'ing, tliat this matter is transacted quite independently of the Health Department, and that the retui'ns are the outcome of tlie joint laboui's of the Registrar-General and Government Statist. Registration Districts coincide throughout the country with electoi'al districts; Ijut when the latter are very populous, or very large, they are divided into registration sub-districts. In the metropolitan division, sub-districts have, as far as possible, the same Ijoundaries as municipalities; but, when tliinly populated areas lie adjacent to municipalities, but outside them, such areas are sometimes included in the registration sub-district, of wliich the said municipality forms the main part. As to Street Names and Numbers within the city of Sydney. Tlie same name is not used more tlian once, and there are not many THB PHESRNT SANITAIJY STATK OP N'RW SOUTH WALES. 4ol 11 n nil ui be red liouses. Tlie foi-iner statement holds good of tlie otlier metropolitan sub-districts, taken severally; but the same name is used over and over again in diffeieiit distiicts. Houses in the more populous districts are imperfectly numbered, and in the less populous, are unnumbered as a rule. Long streets, which i"un through more than one district, are often numbered in part only. No map or index of streets and numbers within their districts are issued to the Registrars. StUl-hirths are unregistered, and it is well known that here, as in other countries, children who Iiave lived even for several weeks have been buried as still-ljoni. The law as to the Registration of Births is defective, especially by allowing an interval of sixty days. It prol^ably helps to swell the numbers who escape registration. The "Registration Act" contains no mention of the Cause of Death. The Registrar-Greneral has power under it to make regulations, which, when gazetted, have the force of the Act itself. In this way, the form of register has been prescribed, and one of its columns is headed " Name of the medical attendant by whom certified," and " When he last saw the deceased." The Registrars are therefore bound to enquire the name of the medical attendant, but are not bound to ascertain wliether the iiame given is that of a legally qualified practitioner, ^ilthough, no doubt, some of them do so. In 1886, according to " Bruck's Medical Directory," there were in the whole province 526 legally qualified, and 18-3 unqualified, practitioners; 83 of the latter resided in Sydney. Certijied and Uncertified Deaths are not distinguished in the regis- ters. Deaths in Public Institutions are not distributed. In the country, there is no reason to suppose that they are in large proportion, and as districts are large, and Hospitals few, error could l)e caused by them only if abstracts for the larger towns were separately published, and this is not done; but the case is veiy different with the metropolitan district. There, in 1887, no less than 15"7 per cent, of all deaths occurred in public institutions. Abstracts of the returns oj' Births and Deatlis aie published monthly for the metropolitan districts only, pursuant on a departmental order of the Registrar-General. Outside this area, aijstracts are published annually only, and the larger towns are not separately reported on. The population which is dealt with in them, under the general heading "countiy districts," is in unknown [)roportions strictly urban and strictly rural (see sections 1 and 2). I now give a detailed account of the important particulars furnished in the monthly abstracts for the Metropolitan disti-icts, and iii the annual abstracts for the whole province. The former are published to the current date, but the latter only to 1885. The Montldy Abstracts for the Metropolitan District (or, the City and Suburbs of Sydney) then, give the following pai'ticulars and calculations (the estimated population at the middle of the cui-rent year is used): — The absolute number- of deaths under each of the eight classes, dis- tinguishing those below five years of age, and the percentage of deaths 1« 2 452 INTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. ill each class to total deaths, are given for the city and for the suburbs separately. Under each class are mentioned the orders most largely represented by the observed causes of death ; and under each order are nientioned the more fatal diseases, number of the deaths due to each being given. Another table enumerates the se^■en districts which form the metro- politan division, and the twenty-four su])-districts comprised in them ; it gives the estimated population of the several districts, and shows the number of births and deaths, distributed under sex, which occurred in the city district and in each of the sub-districts, and gives the per- centage of deaths struck on the estimated population of each of the districts. Deaths in public institutions ai-e here entered separately, and are not used in the calculation just mentioned ; they are included and used in the total for the metropolitan division. A third table gi"\'es similar information for each of the eight wards of the city, but the population of each ward is not estimated. A fourth table, intended for comjiarison, gives the number of births and deaths for the city and suburbs respectively, in the corresponding montli of each of nine previous years and in the current month, and on these ten strikes an average. To tliis table the mean temperature and height of the barometer, and the rainfall in inches and on days, is added. A fifth table gives the deaths under one yeai-, under five years, and at all ages, in the corresponding montli of eacli of five preceding years and in the current montli, for the city and suburbs resj)ectively. These reports open with some general remarks. In the course of them, the percentage of deaths under five, to total deaths, and the monthly millesimal proportion of deaths to the living, are given. The Annual Abst7xicts furnish in several tables the following informa- tion : — Table A, births and deaths in the whole pi'ovince, distributed under sex, for each quarter of the current year. Table D, births in tlie whole pi-ovince in each quarter of nine preceding years and of tlie current year, and the millesimal propoi'tion of births to the population estimated at the middle of each year. Table G is constructed as Tal)le I), but relates to deatlis. Table H is entitled " Infantile Mortality," it gives the total deatlis in the whole province, distinguishing those under five, and the percentage of the latter to th(; former, in each of nine pi-evious and the current years. Talile Ha gives the deaths at all ages (1, 2, 3, 4. 5, and quinquennially up to 100) in the City of 8ydney, in its suburbs, and in the country districts separately. Table Ub contains the births, the deaths (distinguishing those under five), distributed under sex, in each ward of the city ; the enumerated population (18(S1) is added. Table He is the same as H />, l)ut for the whole city and foi- each sub-district in the metropolitan di^ ision ; the enumerated populations are added. Table I shows the centesimal proportion of deatlis under five to total deaths, of deaths under live to births, of tot;il deaths to births, and of total deatlis to the enumei-attnl population in each ward of the city during the current and each of tlie nine previous years. Table J, is con- structed as Table 1, but deals with tlie city as a whole, and each of the sub-districts of the metropolitan division. Table K gives the per- THE PftESEXT SANITAKY STATE OF NEW SOUTH AVALES. 4o3 ceiitage of deatlis under each of the classes and orders of tlie older classification, to the total deaths in the whole province in each of nine previous and the current years. Table L shows the births and deaths in Sydney and in the rest of the metropolitan division, the mean tem- perature and the mean heiglit of the barometer, with the rainfall in depth and on days, for each month of the current year. In an appendix are shown the obsei-ved deaths from all causes, distributed under ages (1, 2, 3, 4-, o, and (juinquennially up to 100), and set against classes and orders of iiiales, of females, and of persons, which occurred during the year in Sydney, in the suburbs, in the country districts, and in the whole pi'ovince during the year (twelve tables). Here there is also a summary table of deaths set against classes and orders of disease, for each month of the year, distributed under sex, and the percentage of deaths under each order to total deaths, for the whole province. Lastly, there is a table which shows the deaths that occurred in each ward of the city, set against classes and orders, distinguishing those under live ; and to this is appended the total deaths set against classes and oi'ders, which occurred in the city in the current and in each of nine previous years. It only remains now to sliowfrom tlie abstracts I have just described, wliat the actual state of tlie public liealth was at the date of the last published returns. No life table has ever been constructed for New South Wales. I therefore give the two tables which follow, and which I have made for tlie present purpose; I believe they contain all the information that is necessary for the present purpose as far as the returns furnish it. It is necessary to observe that they are uncorrected for sex, that they give recorded rates only, and that the estimates of population are rather above the truth in all probability. I do not till up the column for density, for reasons which (in the absence of annual enumeration) may be inferred fi-om what is said under Sections I. and II. The means of making trustworthy comparisons between selected districts do not, in my opinion, exist : — 454 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. CO ■A>t.is.'s::4(f -SHJ.vaff 1VJ.0X oj, -iv5DHaavin asv aioHdAX -siixvaa JO a o V ,L K a J H ri j 1 CO -t< c^ 1^ :c I- 1— ( (M ■^c «i -ti-Ti o OJ CO Jo 6i C m oi o lO c 9 OI i-H OJ i-H •ono'oi «5rHa -vviQ anv aioHdAX K>ms axvH-Hivaa 1 »ffloco;0(Nt-i-Haoo>.-i OIC-^CptOOOt^-OQOC c>i tc --ti C". ""■r oi i: (yi oq i!o CO Ol Ol fM Ol CT i-H O) Ol (M 'SI >* o OJ rH o OJ ■oOO'Ot »ap t-- CO CO >n CO "o- c — n t^ oi c; <>i lis (fi 1?) o OJ 6i th coioco-^ooTfioicoojeo CO CO t- CO CO o s o (S e- a < o o .J ?. X t- Q 26-06 18-41 18-76 20-30 19-S8 i8-7.r 15-63 2117 16-24 17-52 05 OJ X do Enteric Fever. c; US tf o CO >o-x t~ Oi -y^ CD cp O t- -^1 O CT5 lO -^ t- i>- lb OS lb -^ -qt cc o t>- Oi I— 1 o CO -i[Sno,'-i 't 35 X -^05 Ol ^ OJ O -H t~ -T* O X rHrHOO-»<>OrHt--COS5 OO-^C-.O-JfOJOOcb X OJ OJ OJ o X 6 ■dno.io pni!iJi.taii!>ii(ItQ ^COt-OXOJt^OOIOS T^COrHI^-CpwiClipOOJ ocbocbibccrHoiibas lO ■* o ^ oi CO =5 ic o •-:: >i7 C^ O T-H 05 OJ — . C: X rH CC --r -* OJ O O CO OJ CO rH 1— 1 CO X CO OI c OJ COr-oCO—iOCOOJ 16-32 0-06 0-049 9-98 0-614 01-24 0-889 0-250 X OJ 6 1- 0-226 0-746 0-951 0-107 OJ OJ OJ 6 CO 9 o •sH.i.Hifr onoT OJ. 'i aaaKii SHxvau COi— IOC~'— ^-fOJXO oi ^ oi CO -t< OJ c OJ OJ 3; oicbcocbojojcbcbr^ t^COlOC^lOOiCCXCOt^ o 1— ( X X r— ( ■:m.vj[-hxv:iq 2(:-80 24-96 18-82 21-16 19-46 22-96 19-11 20-77 18-75 21-24 OJ -*< ip OJ rHi-l— i — — — lOJi-HOIOJ i-H ■-! -nva_i^ ao a-iuaiK iv aaxvK -IXSJI KOIXVI.l.KiJ 1-H ^ tH -rtH 05 O «0 -tl 05 I OJCil-HC0OOJC0?0'— 105 i-H_ oj_^ -tH_ o o OJ_ I - i^ ira c; rH t^ ^ t^ O' -f t^ — T X' X' «C O l^ X O — ' OI -t< >o C^ I-H rH I-H 1-H OJ OJ OJ OJ OJ OI lO^r^XOSOi-I'MJO'* 6cfl M^gio c~-t-.t^r-i~-xxxxx «s.-^ S'X XXXXXXXXXX SH g'Onn rHi— l*-Hi-^i-HT-HrHi-HrHf-H t>tx^»-^ t>" r-i THE PRESENT SANITARY STATE OF NEW SOUTH WALES. 455 Its 00 '-I -2 C5 456 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. I may mention, in conclusion, that the following Bills and Select Committees have been introduced or appointed by one or other House during the past few years: — During the session of 1885-6, a Public Health Bill was introduced in the Council by the late Mr. Dalley; it was interrupted by Prorogation of Parliament, and not re-introduced. During the same session, a Bill to regulate the practice of Cremation was introduced in the Council by Dr. Creed, and passed ; it was sent to the Assembly, interrupted by Prorogation, and re-introduced in tlie Council ; it was then dropped. A Bill to amend the laws relating to the Medical Profession was introdviced in the Assembly by Dr. Tarrant ; it passed that House, was sent to the Council, and was interrupted by Prorogation. A Government measure to proclaim a site on which Noxious Trades might be carried on, passed the Assembly ; it was sent up to the Council, M'as referred to a Select Committee of that House, and was dropped. During 1887-8, a Factories and Workshops Regulation Bill was introduced in the Council by Dr. Renwick, and passed ; it was sent to the Assembly for concurrence, and was not returned. Two Select Committees of the Council were appointed on motion of Dr. Creed, one to enquire into the law relating to the Registration of Births, Deaths, and Marriages, the other to enquire into the laws relating to the Practice of Medicine ; and they repoi'ted. A Bill to amend the Law relating to the Registration of Births, Deaths, and Marriages, was introduced in the Council by Dr. Creed, and being- ruled by the Pi'esident a money Bill, was dropped, and not re-introduced elsewhere. Leave to introduce in the Assembly a measure to amend the laws relating to the Practice of Medicine was granted to Dr. Cortis, but the Bill being ruled by the Speaker to exceed the leave, was not accepted ; it was re-introduced after amendment, and thrown out. The Government introduced a short Bill to prohibit the Sale of Diseased Animals for food, and to amend the law relating to the sale of Diseased Meat, and was thrown out. A Bill to Regulate Common Lodging- houses was introduced in the Assembly by Mr. Camei'on, and thrown out. STATE MEDICINE IN NEW SOUTH WALES, WITH SOME REMARKS ON THE MEDICAL ACTS OF THE COLONY. By C. W. Morgan, M.D. Tlie thoughtful address of Dr. Whittell, the Chairman of the Section of State Medicine at the First Intercolonial Medical Congress, dwelt on the duty of the State, in providing for the removal and prevention of disease, and indicated the objections to the principle of appointing members of corporations, or of shires, oi- of district councils, to be local boards of health, which his experience of the working of tlie Health Act of South Australia suggested. Dr. Whittell contended tliat the public health was too sacrcid a subject to be committed to tlie care of gentlemen who, not being impressed with its importance, placed STATK MKDTCIXE T\ XKW SOUTH WALES. 457 it in a secondary poi^ition; and, while adAOcatiiig the principle of a central authority, armed with the fullest powers to control and direct local l)oards, he insisted upon the importance of the latter beinni system of dispo.sal of sewage ; the purifica- tion of air, and su])j)ly of pure water ; the reform in the dwellings of the poor, and tlie improvement in the in.spection of the food — all convey STATK MRDICIN'K I\ NEW SOUTH WALES. 461 lessons that should lun e iutliu'iiced our lulers and excited theif emula- tion ; but it is reniackahle tliat, as refoi-niation in puljlic health has progressed in the Ignited Kingdom, our sanitary condition is daily degenerating, througli tlie niost culjiable neglect and mismanagement. And in the absence of legislation to enforce sanitary rules, the very diseases the home authorities are straining every nerve to combat and stamp out, and which experience has proved to be controllable, are gaining ground, and becoming more firmly rooted in the soil of oiir young country. T now proceed to detail the machinery by which the State exercises its power for the preservation of public health in New South Wales. The Colonial Secretaiy controls all the medical service, with the excep- tion of the quarantine officers, who are in the Department of Finance and Trade, under the Colonial Treasurer. Tn all cases of emergency and danger, these Ministers take prompt action, and, being tlie chief members of the Executive, no power in the land could be more efficient. The responsibility of dii'ecting their actions rests with the Medical Adviser to the Government, who is also, Pi-esident of the Board of Health, to which reference has been made. This Board is composed of the Secretary for Finance and Trade, the Inspector-General of Police, and the Mayor of Sydney ex-officio, and of five members of the medical pi'ofession, exclusive of the President, who are appointed by the Gover- nor and Executive Council. Its functions are chiefly those of advice and inspection. There are also a numbei- of Government Medical Officers appointed to country districts. These gentlemen are required to report tjuarterly to the Medical Adviser to the Government, on the sanitary condition of the localities to which they are gazetted, and to pen-form such services as the Government may require of them ; but I do not think they have any connection, officially, with the Board of Health, and their position and functions are defined by regulation, rather than by Act of Parliament. It will be seen that, in some respects, the organisation of the Health Board, at head-quarters, and the Government Medical Officers in the country, resembles the details of the Public Health Acts in the other colonies; but there is this material difference, that there are no local Health Boards, and the duties which such Boards would l>e called upon to perfoun, under the provisions of the "Health Act," fall on the Muni- cipal Councils of incorporated towns, under their special bye-laws. These are framed under the "Municipalities Act," and relate to inspec- tion, drainage, water supply, scavenging, disposal of nightsoil, »tc., without any special reference to sanitary law ; therefore, the control of the causes that lead to epidemics, and the exercise of pi"oper precautions for prevention of disease, rest with bodies who are under no central authority or skilled local advice. If a town is not incoi-por-ated, the suppression of nuisances, or of the causes which lead to epidemics, rests with the police. The officer in charge reports insanitary conditions to the Inspector-General, himself a member of the Board of Health, and active steps are taken; but the Municipal process is much more uncer- tain and unsatisfactory. The routine of reports, reference to conanittee, reception of more i-eports, delay and discussion on adoption, ha\e to be undergone, and, in the me^intime, the opportunity of dealing with the emergency is lost. From an intimate and personal knowledge of the 462 INTERCOLONIAL MKDICAL CONGRESS OF AUSTRALASIA. routine of a Borou)eing 92 J gallons.* ' As regards the composition of the Yan Yean water, the most recent analysis, that of Professor Masson, is contained in the following table, taken from the Second Progress Keport of the Eoyal Sanitary Commission, published since this paper was read : — Aiialffses of Fice Sa)ii2)les of Yan Yean Water from a Tup at the Unicersittj. (Chemical const ituent>i estimated in part^ per million. j Date of collection 13th Jan. Uth Feb. 30th Mar. 23rd April 6th May Teinperatme of the water C. . . 21°-22° 21-6' 21°-22° 17°-18° not detir- mined Colour in 2-foot tube All sample s darkish ye low. Oilour at 40'" C Slight in a 1 Ciises. Reaction Slightly all laline iu all case.s. Total soliils 75 81.5 84 86-5 95-5 Total hardness 7-S 11 1 111 11^1 not deter mined Chlorine ■2:i 21-5 22 24 25-5 Oxygen consumed at 27 -' '" 17""'"*"" ■"' ( in 4 hours . . 1-0:5 1-90 1-07 2-05 109 2-u2 113 2^38 •84 2^CS Free amiuonia * tra:e •006 trace trace •005 Alhnmeuoid ammonia •218 •lao •096 •132 •108 Nitrogen, iis nitrates ■164 •137 •110 •113 not deter mined Nitrogen, as nitrites AUsent in ill cases. Phosi>hates Absent in ill cases. Microorganisms per j lifiuefying 'elatine 20 none none none 5 cubic centimetre "( not liquefj ills ,, 5.0 45 none 1.-. 15 * Free ammonia less than •COS is stated as " trace." 476 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. In connection with the question of water-supply, two questions arise of great sanitary importance — the spread of typhoid fever, and the prevalence of hydatids. (1) Typhoid fever exists in Victoria to an alarming extent. The figures of the President of this Section, Dr. MacLaurin, are sufficient evidence upon this point. More recent statistics show that the disease is rapidly increasing. Thus, during the six months ending May 31, 1889, no less than 5159 cases, 789 of which proved fatal, have been repoi'ted to the Central Board of Health. No doubt, the main starting- point lies in our insanitary surroundings, whilst our contaminated surface and subsoil afford the germs a very prolific breeding-ground. But here, as elsewhere, a polluted water-supply has much to do with the extension of the disease. Already, numerous cases have been traced to polluted tanks and water-holes, and several epidemics have followed the contamination of creeks and rivers.* (2) As to the prevalence of hydatid disease, Victoria still remains the second most infected country in the world, despite the fact that the danger must be materially diminished by the boiling of water in the preparation of the general country drink, " tea." Some years ago, the writer was successful in inducing the Central Board of Health to issue and circulate some 30,000 circulars bearing upon the spread of hydatids, but beyond that, little has been done preventatively. No investigation has yet been made as to the proportionate number of dogs and other animals infected, and no attempt has yet been made to attack the echinococcus pi'ior to its entrance into water. Legal Hygiene. The earliest legislation afiiecting the Public Health in Victoria, was the "Quarantine Act," of 1832, and the "Act for Regulating Buildings and Party Walls, and for Preventing Mischief by Fire in the City of Melbourne." Both these Acts were passed when Victoria was a portion of New South Wales, and, with some amendments, remain in force to the present time. (1) "The Quarantine Act "of 1832, of course, was framed for the exclusion of external disease. Power to take action, without waiting for an order of the Governor-in-Council, has been added under Section 12 of " The Public Health Act, 1888." For the j)ractical enforcement of its regulations, a quarantine station, able to accommodate over 450 persons, is maintained in a higli state of efficiency. There are three salaried Officers of Healtli for tlie Port of Melbourne, and medical officers at Geelong, Portland, Warrnambool, and Port Fairy, who are paid by fees, and their inspection is very thorough. Considerable discussion has, from time to time, taken ])lace as to the quarantine system adopted by Victoria against external infection, the consensus of opinion being, that the system is well suited to our requirements. On three occasions, the passengers, ifec, of large steamers have been quarantined, and as • More recently still, since this paper was read, similar contamination has been shown to be only too probable in tlio case of the Yan Yean water-supply ; and M. de Bavay, a pupil of the Pasteur school, has discovered in great abundance germs, which he and the writer have every confidence, after isolation and cultivation, in reporting as typical tyjihoid bacilli. HYGIENIC CONDITIOXS IN VICTORIA. 477 active measures in vaccination, isolation, and disinfection have followed the few cases of small pox which have gained an entrance, that disease has never yet obtained a jiermanent footing. A sanatorium, suitably situated, and capable of holding some fifty patients, was built several years ago, and is always ready for use. It is maintained by the eighteen Metropolitan Local Boards, on a rateable basis of population, and is under the immediate control of the Central Board of Health. (2) The first Act relating to the internal health of the colony was passed in 1854, but was applicable only to "populous places." This was followed by an "Act to Prevent the Adulteration of Food." In 1865, Act 264 was passed. Part lY. of which, dealing with the prevention of the pollution of the River Yarra, and Part YI., relating to quarantine, are still in force. This was followed, in 1867, by Act 310, of which the portion, governing Cemeteries, is still in operation. Then came Acts 436 and 524, both of which have been repealed. (3) Some of the sections of the foregoing Acts, together with a number of new provisions, and many sections based on the great English "Public Health Act" of 1875, were incorporated in 1883 in our " Public Health Amendment Act, 782." This measure was in foi'ce in its entirety until the end of last year, when " The Public Health Act, 1888," was passed. Now it is referred to as " The Principal Act." The basis of this Act is, that a central authority composed of persons not exceeding nine, appointed by the Governor-in-Council, shall exercise a control somewhat similar to that vested in the Local Government Board of England. The non-salaried members (except two, who are Members of Parliament), draw fees of two guineas for attendance at each ordinary meeting, the total paid to any member, not however to exceed fifty guineas per annum. The Board is composed of three practising medical men (one of them being the Government Medical OfHcer), the two Professors respectively of Engineering and Chemistry at the University of Melbourne ; the Director of the Technological INIuseum, the Government Analyst, a Bank Director, and a practical business man of long Colonial experience, with a Police Magistrate as President. The local and primary authority on sanitary matters, vests in Local Boards, one for each Municipal District, and the members of the ]\[unicipal Council for the time being, form such Local Boards ; every City, Town, Borough and Shire, being a separate Municipality. With the exception of some mountains in Gippsland, and the West Melbourne Swamp, the whole of Yictoria is divided into Municipalities, there being 8 Cities, 9 Towns, 42 Boroughs and 128 Shires. Total 187. Local Boards have the power of making sanitary By-laws, and must make them, if required by the Central Board so to do. At present, 170 Municipalities have By-laws more or less complete, not including a series of By-laws passed by the City of Melbourne, some of which are excellently framed. Nearly all the Cities and Towns have well-drawn building regulations adopted under the " Local Government Act." The City of Melbourne and the Town of Geelong, were incorporated and given special powers before the separation of Port Phillip and its creation into a separate Colony. 478 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. The Act requires each Local Board to appoint a Medical Officer of Health, and also provides for the appointment of Analysts and Inspectors of Nuisances. The Town Clerk, or Shire Secretary, always acts also as Secretary to the Local Board of Health. Nuisances, adulteration of food, offensive trades, infant life protection, unhealtliy dwellings, infectious diseases, control and regulation of dairies, removal of excreta and liouse refuse, closing of polluted wells -and tanks, and the inspection of certain public buildings, are the principal subjects that daily come under the attention of Local Boards and tlieir Officers. As already stated, the Central Board has, to some extent, a controlling power ; and in some cases of default on the part of a Local Board, can enforce action, or may direct the Police to prosecute offenders against the Act. In addition to this, the Central Board has the administration, under the Chief Secretary, of all matters relating to quarantine, of vaccinations throughout the Colony, and of cemeteries. No theatrical licenses are issued witliout the Central Board's previous approval of the building, and churches, concert rooms, stands on race courses, and cricket grounds cannot be opened to the Public, without the previous consent of the Board. For the foregoing account, I am indebted to the kindness of Mr. Akehurst, President of the Central Board of Health. In pvirsuance of the powers thus vested in it, the Central Board has continued to act with considerable vigour. In August 1884, it drafted and forwarded to all the Local Boaixls, a pamphlet of instructions for tlieir guidance ; and since then, it has issued model bye-laws upon the questions of their duties, regulations for the prevention of the spread of infectious disease, memoranda for the suppression of cesspools, the suppression of nuisances, tlie methods of disinfection, and instructions to officers of healtli. In addition to the annual report to the Govern- ment, it has circulated valuable papers on the prevention of small pox, the treatment of measles, diphtheria, croup, pertussis, and typhoid fever, in the absence of medical aid. Recommendations, in view of cholera outbreaks, on liydatid disease, closet and urinal construction, improved stT'eet, gutter, and open drain construction, the building and manage- ment of public structures. It has been specially energetic in pointing out how to deal witli typhoid fever on railway and water work camps, and in disposing of excreta; and in 1887, it issued a special report to Parliament on the whole question, a report which was very favour- ably reviewed in The Lancet. Its final annual report, for 1887-1888, is a document of eighty-eiglit pages, which afibrds ample evidence as to the time and attention which the Central Board has given to its important duties. This report r-efers to the frequent failure of duty on the part of Local Boards, to the fact that only fifteen boards had attempted to carry out the law as to tlie adulteration of food. It deals with tlie treatment of threatened small-pox, and supports tlie Victorian practice of quarantine as, under oui' circumstances, safer and more efficient than the Englisli system of medical inspection. Under the heading of nuisances, it discusses the important questions of the Elwood Swamp, the Port Melbourne Lagoon, the West Melbourne Swamp, and HYGIENIC CONDITIONS IN VICTORIA. 479 indiA'idual complaints, eighty-two in number. It lays special stress on the want of public urinals and closets; and in view of the serious danger to health from the conunon practice of speculators in land, cutting up blocks without nudving sufficient pro^■ision for I'oads and drainage, and submits a series of ckiuses, bearing ujjon these points, for Parliamentary approval. Matters of vaccination, quarantine, water pollution, abattoirs, polluted mattresses, drainage of stables and piggeries, overcrowding in asylums, and buiial of nightsoil on Crown lands, also receive intelligent and suggestive attention. Further, a general state- ment is given of the sanitary state of the colony, and a synopsis is presented of the reports from 185 of the Local Boaixls, containing a detailed account of sanitary matters in their midst, and of the chief facts observed upon offici;d inspection. A perusal of this report, there- fore, wliicli is procurable on application to the Central Board, furnishes a fair way of arriving at an intelligent conception of many of our hygienic conditions, and tlie difficulties that stand in the way of their amelioration. (4) To improve the state of matters tlms shown to be very unsatis- factory, the "Public Health Act 1888," was introduced. Most unfortunately, this Act was not brought forward until the A^ery end of Session, and to be passed at all, it liad to be passed without any discussion, and in a mutilated form. i\Iany important Amendments, liowever, were enacted. Thus, additional power is given to the Aarious authorities to enforce sanitary regulations, especially against typhoid fever. The jVlinister may define what are infectious diseases under the Act, may order the enforcement of regulations, and in any emergency, perform all or any of the functions of the Local Boards. Notification of infectious disease is made compulsory upon medical practitioners, X'egisti'ars, school teachers aiT,d members of the police force, as well as householders, and provision is made to ensure the value of such notification. A separate service in enjoined for the removal of typhoid excreta, and their disposal by fire. The Health Officer is empowered to question masters of ships, or passengers, as to infectious disease, and the Central Board may act instanter. Penalties are provided against over-crowding, and the continuance of nuisances. To prevent water pollution, the sanitary authority is made a riparian proprietor, proofs in court are simplified, and the penalties for food adulteration are raised. (5) Conflicts of opinion, however, were still permitted, and arose between the Central and the Local Boards, and in the compromise mentioned above, important clauses, such as those regulating the powers of the Central Board, the disposal of nightsoil, the completion of rights-of-way, and the subdivision and drainage of land devoted to building purposes, had been sacrificed. Hence, there is at present before the Legislature a Bill, the main objects of which are the establishment of a Department of Health, with a responsible Minister, and the enactment of clauses equivalent to those previously aban- doned. Such is an ab,stract of the general sanitary legislation of the Colony. It may perhaps be claimed with justice, that it shows an appreciation of the importance of the subject, and a desire, progressively, to grapple 480 IXTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. with it. Apart from the general apathy and ignorance, howe^'er, to which are due, here as elsewhere, most of its defects in construction and scope, it must be admitted, that a great source of failure has always been present in its inefiective execution. The great need of both Local and Central Boards indeed has been, not so much increased powers, as more inspection and better execution. Special sanitary legislation, however, has not been forgotten. (1) In 1874 a "Compulsory Vaccination Act "was passed. This Act requires that every child be vaccinated within the first six month's of life. All the necessary machinery, including an admirable Calf Lymph Depot, has been provided. In 1887, the number of public vaccinators was 180, the fees and travelling allowances amounted to £5186 19s. 6d., and 85-85 per cent, of the children boi-n in the Colony, are recorded as successfully vaccinated. The quantities of calf and humanised lymph respectively, received and issued at the offices of the Central Board during the year, are given below : — Received. Issued. Calf Lymph from the depot, and Humanised from various Public Vaccinators. To Public Vaccinators. To Private Medical Prac- titioners. Sent to Qua- rantine Sta- tion. |.| Total sent out. Calf lymph . . Humanised lymph . . 15,690 points 3,425 tubes 11,861 1,395 1,966 654 182 170 592 429 14,601 pomts 2,648 tubes The above is exclusive of the calf lymph used in direct vaccinations at the Calf Lymph Depot. It still remains possible for unqualified men to vaccinate, provided qualified men sign the certificate, and there is no power to re-vaccinate in cases of necessity. Clauses to remedy these defects were introduced in the Amending Health Bill, but met the fate of all opposed alterations. (2) There is a " Pharmacy Act," regulating the sale of poisons, and the registration and education of chemists and druggists. There is also a " Dentists Act, 1887," placing the dental profession upon a similar satisfactory footing. The number of registered chemists is over 600, and of registered dentists, 486. (3) The insane and inebriate are also legally provided for. Until last year, provision was made for their treatment by the " Lunacy Statute," as amended by Act 342, and the " Inebriates Act, 1872," as similarly amended. These are now repealed, and replaced by the "Lunacy Amendment Act, 1888," and the "Inebriate Asylums Act, 1888." J5y " The Lunacy Amendment Act," orders are made for conveyance to a receiving house, which may be part of an asylum, or separate therefrom. Tliere the superintendent may dischai'ge the patient, if not, HYGIENIC CONDITIONS IN VICTORIA. 481 in his opinion, insane; or, if in doubt, may take medical opinion, and in case of disagreement, abide by the opinion of a second medical practitioner. When, however, he considers the patient insane, two medical men are to examine him, and if they agree, discharge or certify him as insane, as the case may be; if they disagree, the patient is to be examined before a police magistrate, upon fresh evidence, and his decision is final. Not only is the course of procedure thus authorised, both cumbersome and unnecessary, but, as the writer has pointed out, the medical practitioner who signs the certilicate in the fii'st instance, has to certify tlie patient as insane, though, within three days, his certificate has to run the gauntlet of one, two, or three fresh opinions, the result being, that he dare not certify a patient in an early stage for fear of subsequent proceedings. Thus, the value of a receiving house is reduced to the minimum. Other clauses deal with the yearly examina- tion of all asylum patients, the boarding out of harmless patients, the establishment of separate accommodation for paying patients (all private asylums having been aliolislied), the separation of tlie criminal insane, and the establishment of philanthropic hospitals, in which patients may be maintained and cared for without charge. By "The Inebriate Asylums Act, 1888," suitable places may )je proclaimed as such asylums. To these, an inebriate may be committed on his own application, or on the certificate of two medical men, to the effect that he requires curative treatment. The term must not exceed three months, without subsequent ordei's, made on similar grounds. The expenses come from the inebriate himself, and penalties are pro- vided against improper treatment. (4) By "The Shops and Factories Act," provision is made for the sanitary condition and inspection of all shops and factories, and for limitation in the hours of labour. No childi-en under thirteen years of age are allowed to work therein, and for all under sixteen years of age a medical certificate must be obtained from a duly appointed officer, the fee being Five shillings, payable by the applicant. (5) The legal status of the profession is regulated by a " Medical Practitioners Act, 1865." This provides a nominee board of registra- tion, the requirements for registration being a three years' course of study, "to the satisfaction of the board." Penalties are imposed for the assumption of certain medical titles (from which, howevei", oculist and aurist are absent), to be recovered by any person suing in the County Court. Until recently, such prosecutions were undertaken by the police, but a late remarkable order from the Chief Secretary has forbidden such action. The unrepresentative character of the board, the absence of power to erase names from the register, the scanty re- quirements in the matter of medical education, and the want of defini- tion as to power of prosecuting, on infringement of the Act, have proved so damaging to the utility of tlie present Act, that the profession has under consideration an amended bill, which it is hoped will be intro- duced before Parliament during the present session. Meantime, though quackery is very much on the increase, unqualified men have no legal status ; and in only two instances do they hold office in institutions which receive a Government grant towards their maintenance. As I'egards the profession, numerically, Hayter's "Year Book" for 1887 states that, li 482 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA at the last census, there was one practitioner for every 1 900 persons. The proportion, however, is constantly being diminished, and at a somewhat rapid rate. It would be unpardonable in this connection, to omit all mention of the Medical School in connection with the University of Melbourne, established in 1862. It has turned out more than 200 graduates in medicine, and has 236 students at present attending lectures. The course prescribed is five years in duration, four of which include hospital attendance. The range of lectures is comprehensive, the examinations noted for their severity, and the clinical facilities ample for all requirements. (6) Lastly, Charitable Institutions are numerous, largely endowed by the State, and under State supervision. The returns of the Inspector for Charitable Institutions for the year ending 30th June, 1888, show that there are 34 hospitals in the colony, with 1289 beds for male, and 681 for female patients, with a daily average of 1455; the total number of 16,004 in-patients ti'eated, and 43,334 distinct out-patient cases treated. There are also 10 institutions which are both hospitals and benevolent asylums, with a daily average of 211 hospital and 267 benevolent cases. There are also 6 benevolent asylums, with a total of 1974 patients; 7 orphan asylums, with 834 inmates — 331 boarded out, and 148 in service. There is an infant asylum with 59 inmates ; a blind asylum with 102 ; a deaf and dumb institution with 66 ; 4 female refuges ; 2 convalescent homes, with 10 male, and 17 female beds. In addition, there are numerous benevolent disjDensaries, private chari- ties, nursing and maternity societies ; Charity Organisation Society ; and a Hospital Sunday Fund, which this year collected the large sum of £14,691 14s. lid. The actual results which follow from the hygienic conditions which have thus been described can, perhaps, be best illustrated by the presentment of the vital statistics, and expectancy of life, as compiled by recognised authorities. Vital Statistics. - Book "for 1888:- -The following table is taken from Hayter's " Year Death-Rate at Various Ages in Different Countries. ColTNTUIkS. NuMBEK OF Deaths PER 1000 LIVING AT EACH AGK. Under 5. 38-6 63-6 5 to 10. 10 to 25. 25 to 45. 45 to 55. 55 to 65. 65 to 75. Victoria .. 3-5 6-6 3-9 5-5 10-2 10-2 16-2 17-4 29-1 31-8 59-4 Englaud . . 64-3 United States . . 58-8 10-1 5-4 10-8 17-6 27-2 51-4 France . . 75-6 9-2 8-8 12-7 16-6 28-3 66-3 Prussia . . 9-2 6-4 11-5 18-6 33-0 64-5 Austria . . 111-7 9-8 6-6 11-3 21-1 41-5 92-8 Switzerland 8.5 6-3 11-6 19-3 38-4 82-5 Italy 110-6 11-6 7-8 11-7 17-3 33-1 70-1 Spain 106-2 11-7 8-8 12-9 23-8 42-0 95-0 Belgium . . 68-1 12-7 8-1 12-9 19-0 32-3 74-5 Sweden . . 57-6 8-0 4-8 ^•2 14-7 27-4 62-6 HYGIENIC CONDITIONS IN VICTORIA. 483 Expectancy of Life. — Tlie followin<^ table is taken from a work just published by the Goveriuiieiit Statist of New South Wales, and entitled, "Tlie Wealth and Progress of New South Wales" :— Expectation of Life at Various Ages. Birth 5 years 10 „ 15 „ 20 „ 25 „ 30 „ 35 „ 40 „ 45 „ 50 „ 55 „ 60 „ 65 „ "0 „ 75 „ 80 „ New South Wales, Victoria, AND Queensland s ^. 50-3 46-2 42-1 38-4 34-7 31-0 27-4 23 -S 20-3 17-0 13S 11-0 8-5 6-4 4-7 35 2-4 M. F. 4()-5 49-6 53-0 55-4 49-2 51-7 44-9 47-4 40-S 43-3 37 39-4 33-3 35-7 29-7 32-3 26-2 28-9 22-9 25-6 19-8 22-3 16-7 18-S 13-8 15-5 11-2 12-5 8-9 9-7 6-9 7-2 5-4 5-7 4-,) 4-2 3-0 3-2 En(;laxi>. Holland. Belgium. Sweden. M. P. 41-9 51-5 48-2 45-2 53-6 50'3 39-9 42-1 33'2 34-1 26-5 27-5 19-9 20-8 13-6 14-5 se 9-1 5-2 5-6 2.S 31 31-4 48-7 45-9 38'3 3i'8 25-0 18-5 l^'-8 7'9 4-4 2'4 36-4 49-2 46-5 39-2 3'2'4 2(3-4 19-7 13-3 8-1 4-5 2-7 M. 43-8 44-8 41-3 49-4 46-5 45- 53- 50- 3(3-4 37-7 38-6 42- 30-5 31-9 3i'-2 34- 24-8 20-1 24-3 27- 18-9 20-3 18-0 20- 12-4 13-9 12-3 IS-. 8-1 8-3 7-4 s-( 5-2 5-4 3-9 i\ 2-9 3-1 2-4 2\ 47-0 393 32-1 25-0 18-0 li-7 6-9 3-0 48-7 42-2 35-3 28'2 20-9 14-1 %h 44 Vide A. F. Biirridge iu "Jounial of Institute of Actuaries," vol. xxiv. Summary. The following general statements will, in the opinion of the writer, be found to give a fail- summary of the hygienic conditions of the Victorian people : — The typical Victorian individual is healthy, but neurotic. He eats far too much meat, lives in a climate characterised by its variability, and generally wears clothing ill adapted to his surroundings. The result is that, upon his endowment, he is rapidly grafting a distinct hepatic tendency. This is accentuated by the fact, that if a drinker, he takes alcohol in greater quantity and more injurious form than the average Englishman. In his favour, however, it must be said that his hours of labour are light, and his social condition and general physical and mental environment such as should conduce to health. In his educational .system, however, sufficient prominence is not given to certain fundamental moral elements. Taken as a member of a com- munity, he would naturally enjoy an unusually long and healthy life, did he not allow himself to be surrounded by numerous preventile causes of disease. His water supply, in the country, is very frequently contaminated by the germs of hydatid disease; and, in the settled districts, it is becoming more and more liable to sewage pollution. It is when we look, however, to his surroundings as a citizen that we meet with the main factors of his corporate ill health. His household con- struction is frequently bad, liis surface conservancy generally worse, and his system of drainage and sewerage always worst of all. Regarded li 2 484 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. from .a medico-legal point of view, he is found enjoying the benefit of more valuable legislation, perhaps, than is the case in any other colony ; but, ineffective execution and municipal neglect, combine with individual apathy to deprive him of most of its beneficial results. After all, however, the fact remains, that the expectation of life and death-rate of the community, compare favourably with those of most other civilized countries, though they sink much below what might be reasonably expected. In conclusion, a brief resume of the main factors of Victorian disease may not be out of place. In thus giving an individual opinion, the usual terminology adopted on such occasions is discarded, partly because such classifications are always full of errors, but mainly because results and modes of death are therein discussed, rather than actual operative causes. I venture, therefore, to advance the statement, that the main factors of Victorian disease are insanitary surroundings, hepatic vulnerability, and climatic variability. The extent to which tliese are present, may be gathered from the foregoing pages. The three are so interwoven in their operations, that their separation is frequently impossible. Giving them, however, a sejDarate existence, it may perhaps be said with justice, that our insanitary surroundings are responsible for the wide extension of typhoid fever and diphtheria amongst us — not to particularise other less common forms of germ disorders — for the prevalence of hydatid disease, and an indesci'ibable amount of general ill health, which assumes many local forms, and upon which the seeds of future disease of many kinds are found to flourish. Similarly, it may be said, that our hepatic vulnerability is responsible for all our liver complaints, for much of our circulatory, renal, and nervous disease, and for a large percentage of our rheumatism. Finally, to the extreme variability of our climate, we owe a vast quantity of respiratory disease, culminating in phthisis; a large proportion of our infant moi^tality, many diarrhceal and hepatic disorders, and the greater portion of our rheumatism. For all further information, as to the extent to which each separate foi'm of disease prevails in our midst, the reader is referred to the reliable and exhaustive tables which formed the l:)asis of Dr. MacLaui'in's most valuable presidential address. I cannot conclude without thanking Mr. Ellery, the Government Astronomer; Mr. Akehurst, the President of the Central Board of Health; Mr. Hayter, the Government Statist; Mr. Coghlan, the Government Statist of New South Wales; and Mr. Davidson, tlie Engineer of the Water Supply Department, for the very great assistance which they have afforded me in the collection of much statistical and otlier matter. THE SANITARY CONDITION OF NEW ZEALAND. 485 THE SANITARY CONDITION OF NEW ZEALAND. By Leger Erson, L.R.C.P. Late Honorary Physician to the Auckland Hospital. The health and well being of the GOO, 000 people who are scattered over the wide area comprised under the general heading of New Zealand is, legislatively, under the control of " The Public Health Act of New Zealand, 1876." The machinery which is thus provided, comprises a Central Board of Health, Local Boards of Health, and Road and High- way Boards. The Centi'al Board of Health consists of His Excellency the Governor, the Executive, a retired sea captain, and a medical man, who is also othcial visitor to the various hospitals and asylums of the colony. A Board so constituted, and so busied in many other import- ant duties, cannot be expected to grapple, either energetically or successfully, with the great questions of State medicine. Still, it is as discreditable as it is surprising, to find how little work it has attempted. It has not sent an official communication to the Local Boards of Health for five years, and then only in the form of a few stereotyped questions regarding local sanitation, and without taking any action thereon, although incentives to such action were by no means lacking. The whole burden of the care of the public thus falls upon the Local Boards and Road Boards ; the latter have jurisdiction only in places situated outside the corporate boundaries. Being unofficially advised, and largely com})Osed of small farmers, elected from time to time to superintend such useful work as road-making, etc., they rarely take any steps to enforce sanitary ]n-ecautions; and the utility of their functions does not deserve any serious discussion. The health of the people is thus, practically, left in the hands of the Local Boards of Health, or in other words, the various Municipal bodies throughout the colony. The Auckland Borough Council, in its capacity a,s a Local Board of Health, is taken, as giving a typical examjile of this j\Iunici|)al Health administration in New Zealand. The Sanitary Staff and Health Department, for this city of 00,000 people, comprises the City Councillors, a Medical Officer of Health, a Sanitary Engineer, an Inspector of Nuisances, scavengers, and a dog catcher. The drawbacks to constituting a city council a health committee, are everywhere those of connnitting health matters to those who are generally ignorant of the suljject, without time to attend to its requirements, too easily removed from their office, and too likely to be influenced by personal or ijetty motives. These drawbacks, of course, are not absent in New Zealand. Again, that the Medical Officer of Health should be without a si)ecial <|ualification in State n)edicine, and allowed private jji-actice in addition to his official duties, is a state of matters b}' no means confined to New Zealand — however desirable the opj)Osite may be. But it is a gieat and adilitional disadvantage when, as with us, he should receive ])ayment only when his services are asked for, and that his remuneration should be less tlian that enjoyed by a city scavenger. Further, as elsewhere throughout the colonies generally, our Inspectors of Nuisances are appointed rather for their general usefulness than foi- any approved 446 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. knowledge, or experience in sanitary matters. But nowhere else^ j)erhaps, has tliat officer snch an enormous amount of extraneons work as with us. It may amuse readers to know, that he includes the follow- ing amongst his duties : — Dog Registrar, Kerosene Inspector, Inspector of Hackney and otlier Carriages, Inspector of Lodging Houses, of Butchers' Shops, Prosecutor in cases of Breaches of the City Bye-laws, and Issuer of Licenses to Ti'am Drivers and Conductors. He has, also, to supervise the removal of nightsoil, the laying of dust, as well as attend to all correspondence, receive all reports on infectious diseases, and keep a return of the same. Can one wonder, if nuisances do accumulate somewhat, even when the inspector is most anxious and Avilling to remove them ; and can one wonder, if infectious and other disease multiplies also, often to an alarming extent. A striking example of how such a Health Committee may labour, in the presence of an epidemic, was given during last season, when the City Fathers, becoming alarmed at the results of sanitary neglect, actually stopped the publication of the health retui'ns, under the pretext of preventing alarm. The public, however, became both alarmed and indignant, and the City Fathers fled to the local Medical Association, confessed their shortcomings, and asked for guidance. After due investigation, we found that the whole system of sanitary administration was faulty, insufficient, and delusive ; while possible sources of infection for the typhoid, then prevalent, were ^discovered in almost every municij)al district. The main sewer was not properly ventilated, and discharged itself, close by the frozen meat works, into the harbour, almost adjoining the wharves. Abattoirs existed, full of abominations, not far from the source of the water supply. Human dwelling places were discovered, which only allowed for breathing purposes :250 cubic feet of air for each of the unfortunate peojile who occupied them; untrapped sewers; open side drains, with channels but seldom flushed. Dairies were re[)orted reeking with poisonous exhala- tions, from befouled surroundings of decomposing animal or vegetable filth. Thus we have the eloquent fact, and I ask this Congress to note it, that the Munici})ality of the largest city in New Zealand admittedly confessed their inability to fulfil the duties assigned to them by the Act of 1876, as a Local Board of Health, and had, in their difficulty, to ol)tain the advice and guidance of a body of medical men. The condition of aftairs just recapitulated, so far as relates to the Northern c;i})ital, but reflects a similar unsatisfactory state in matters appertaining to the public health throughout the colony. Towns are laid out and Iniilt without due provision being made for sewerage and water supply. Transitions are gradually taking place from the hamlet to the village; the village to the town, and from the town to the city, without a thought being given as to the disastrous eft'ects attendant upon an increasing population, when associated with the steady accumu- lation of insanitary surroundings. It, indeed, appears in many instances as if history would repeat itself, and that no awakening would take place until a succession of dire epidemics decimated and horrified a repentant and alarmed people. From all sides come requests for water supply, and waste ))ipes are placed in every direction, while the petitioners remain ol)livious or careless of the fact, that if adequate sewerage be not provided at the same time, it were far better and safer 1 THE SANITARY STATE OP NEW ZEALAND. 487 that the water supply liad never been obtained; since the more sewerage is dihited, the more will it penetrate the soil, and unless let off in proper channels must increase decomposition, and ultimately poison the in- habitants. This will account for the apparent anomaly of some boroughs with no water supply, escaping typhoid; whilst others, who are so supplied, become infected. Independently altogether of the loss of valuable lives and of useful labour to the State, the aggregate cost to New Zealand, which has been attendant upon the absence of proper sanitary administration, must be enormous. One little epidemic cost an already impoverished Town Council a trifle of over £5000 for the care of typlioid victims within the borough. The Seaclifie Asylum, which was built at a great cost to the country, had to be almost re-erected, to remedy defects in drainage, which threatened to make the building unlit for human habitation. In like manner, public buildings have been erected and are even now being erected, without proper sanitary inspection or supervision, with the inevitable result, that in a little time they will also be condemned, and upon an already burdened colony will fall the ultimate loss. I found Wellington insanitary, and zymotic diseases prevalent, and that in Dunedin no provision had been made for victims to infectious diseases, although many were reported; whilst the general hospital was built on what is known as made ground, and on principles now generally con- demned for such institutions. I found, in Invercargill, the city laid out on a flat, but three feet above the level of the sea, whilst the wards of the local hospital were ill ventilated, and conveyed to the visitor a sensation of stifling. I found, at Napier, a swamp, which for want of pi'oper di'ainage, periodically injured and endangered the health of the whole community. I found school-rooms so designed, that the rays of light struck the eyes of the pupils obliquely, from windows on the various sides of an octagon. I found public refuges, which upon measurement, allowed but 385 cubic feet of air for the breathing space of the unfortunate inmates, while everywhere, evidences were afforded of the want of ])roper sanitary supervision, and of the truths contained in the fact, that good drains and sewers vvill never be properly constructed until regularly organised Boards of Health have competent sanitary engineers and strict })lumbing laws. Now to the conclusion of the matter. It is useless to blame this or that for the spread of zymotic disease, when the whole system of sanitary administration is faulty, inefficient, and honeycombed by iucom])etency. Inflnitely better to go at once to the root of the evil, and relieve Municipal Councils of duties they should never have under- taken. At present, the whole business seems to have a premium laid upon ignorance, since we know that these bodies are, with few excep- tions, avoided by the best colonists as they would avoid leper- houses. The sole IMunicipal control of the Public Health, as practically adopted in New Zealand, is but a relic of the old English system, which has long since been discarded in the mother country. It was swept away at the instance of Sir Charles Dilke and the English Local Government Board, with the happiest results; whilst the death-rate has since been lowered to a figure hitherto unknown in the United Kingdom. America also tried the .sole Municipal control system, but there also it was attended with disastrous results, so it has been replaced by the 488 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. establishment, over the length and breadth of that continent, of State Boards of Health, which, being well organised and administered, have already achieved grand results, to the lasting benefit of the great American nation. Canada, in like manner, had a sole Municipal control of health system, to be again rejilaced by the provincial Boards of Health, which are now doing good work all over the Dominion. It has been my privilege, Mr. President and Gentlemen, to have travelled in recent years over America, Canada, and many parts of Europe. T would, therefore, desire to bear testimony to the fact, that in no part of the world have I found sanitaiy administration attain a higher standard of efficiency, than in the Dominion of Canada. The svstem, therefore, which commends itself most to my judgment as the best for New Zealand, is a modification of the one adopted in Canada. Since there are now engaged in the control of educational matters in New Zealand a Minister of Education, with a large number of School Boards, who are again furtlier assisted by a larger contingent still of School Committees — and as the care of the Public Health is at least of equal importance to any country or people, T would, in like manner, suggest the establishing of a threefold cordon of sanitary administration throughout the colony. The first line of defence against the ravages of preventible disease would be the ci-eation of a Minister of Public Health. To him should be submitted, for final adjustment, any differences, when such may arise, between local and provincial Boards ; and he would be held responsible to the Parliament of the colony for the care of the Public Health. The second (and, to my mind, the most important) line of defence would be the establishing of a Provincial Board of Health, consist- ing of seven members in each provincial district of the colony. They should be elected triennially; and amongst the members of the respective i)rovincial Boards, there ought to be at least one medical man, a sanitary engineer, and one analytical chemist. Three members of each Provincial Board to be elected by the Governor- in-Council, and the remaining four by the Local Boards of Health, to be hereafter described. The jiowers of the Provincial Boards of Health to be analogous to those now exercised by the Central Boai'd of Health of Victoria, and their relations to the Local Boards to be of a similar character. The last line of defence would be the Local Boards of Health, one of which to be established in each town or district containing 4000 people and upwards. They should be elected solely for the })urpose of attending to matters affecting the public health within their resjiective districts, whether directly or indirectly, and be guided in all large matters, such as water su})])ly and sewage, by the Board of Health of their provincial district. Such, briefly, is the scope and direction of these proposed measures of sanitary reform; measures wliicli, I am convinced, are necessary and essential, not only to the well being of the people, but to the good name of the colony. Doubtless a minister may arise there, and declare as we have already heard here, that public opinion is not ri|)e for the changes indicated. Let the answer be to such political weaklings, that reform should ever j)recede, and not follow, jjublic oi)inion. The cost attendant ujton some of my ])roposals may also be objected to; but compared with STATE MEDICINE IX WESTERN AUSTRALIA. 4i59 the great good that would follow their adoption, the outlay bears but little comi)arison, and would repay a hundred fold. New Zealand, once purged from the consequences of sanitary mal-administration, would shew a national longevity, hitherto nuattained by any nation in any clime. Aided by her glorious climate and great natural advantages, this lovely country would then take the ))roud place which a bounteous Providence has apjiarently assigned to her lot, that of being the sanatorium of the Southern Hemisphere, and one of the gardens of the world. In conclusion, let me add with Bryce, that if the voice of science be unanimous as to the necessity for sanitary measures being taken in the interests of the Public Health ; if the more thoughtful and intelligent of the public are one in their opinion, as to the desirability of sanitary laws being passed ; if foi-eign states press upon the country the urgency of international quarantine and sanitary legislation, for mutual benefit and j)x-otection ; if statistics from the most civilised states of Europe and America incontestably prove the incalculable advantages to the State, from the annual saving of many lives, and of the expenditure of immense sums of unproductive capital in the treatment of disease and the burial of the dead; if thousands of homes, desolated by the scourge of epidemic diseases, and untold memories, sad and sorrowful at the thought of what might have been, had not pale death cast a sable pall over fair hopes blighted, and {)romises unfulfilled, are not to pass unheeded, then can the wisdom be doubted, the urgency questioned, or the necessity denied, of speedy, thorough, and extended measures being taken by the firm, yet not harsh, hands of the men who guide the ship of State in her appointed course towards the desired haven— the people's good. Can there be any doubt that the people of New Zealand are not only willing, but anxious, for reform in the direction indicated 1 STATE MEDICINE IN WESTERN AUSTRALIA. By J. R. M. Thomson, M.B. Melb. District Medical Officer, York, Western Australia. In order to render a series complete, I have written the following account of the legislative enactments in Western Austialia with regard to medicine. The "Ordinance to Regulate the Registration of Medical Practitioners " was passed by the Legislative Council in 1869. By this act, provision is made for the registration of medical j)ractitioners on production of diploma ; but there is also a })rovision for the registration and licensing of persons who are not able to produce a dijiloma, if they are able to prove to the satisfaction of the Licensing Board that they are possessed of sufiicient skill in medicine and surgery. There is also provision to punish ])ersons who falsely rejtresent themselves to be qualified. By the provisions of this Act, no unqualified person can recover fees for medical attendance in a court of law. 490 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Other Acts relating to matters affecting the profession are those concerning lunatics, quarantine, vaccination, and public health. I shall treat of these seriatim. The Lunacy Act is a copy, to all intents and purposes, of the ordinary enactments on this subject ; it provides for the proper examination of persons alleged to be lunatics, by two medical practitioners, and the form of medical certificate is the same as in England and the colonies. Quarantine is also the same as in other British communities ; but there is a " Land Quarantine Act," by which, on the outbreak of infectious diseases, special regulations may be enforced to prevent the spread of infection, by isolating the house in which the disease occurs. Vaccination at the age of three months is compulsory in Western Australia ; and on account of the vast extent of the colony, provision is made by the Vaccination Act for vaccination in the more remote districts hy appointing vaccinators occasionally to make special journeys into the country. Inoculation with small-pox virus is an offence punishable by fine and imprisonment. The Public Health Act is a recent one. It provides for the appoint- ment of a Central Board of Health, and of Local Boards in the ])rincipal towns of the colony, and such other places as may be recommended by the Central Board. These Local Boards have ever}'- thing to do with sanitation, and their officers are empowered to secure the punishment of oflfenders. SEWAGE DISPOSAL. By W. F. Taylor, M.D. Diplome iu Public Health, Koyal College of Physicians, Loudon. Member of the Sanitary Institute of Great Britain. Judging fi'om the present insanitary condition of many of the cities and towns of these colonies, the subject of sewage disposal does not ai)i)ear to have been fully understood by the various local sanitary authorities. In the following i-emarks I shall endeavour to detail, as briefly as possible, the result of my investigations with regard to this very im])ortant matter: — The removal of excreta by water is the cleane.st, most convenient, quickest, and cheapest method in all cases where a public water supj)ly exists. Sir Joseph Bazelgette says : — " There are few who will not now recognise that the removal of the refuse of large towns by water, is so vastly superior to any other known method, as to have caused it to be an essential in these days of civilisation and refinement." As channels must necessarily be made for the conveyance of the water used for baths and other domestic purposes, such as washing, cooking, d'c, some urine, and trade products, they can be used with little alteration SEWAGE DISPOSAL. 491 for tlie removal of excreta also. Tlii.s does not apply, however, to such cities or towns where the system of surface sewerage pertains; where the water tables of the streets are made to do the duty of sewers, and house drains are not the rule, but the disposal of slop water, by throwing it on the ground at the back of the kitchen, the almost general l)ractice. In such places immediate sewering, with proper house drains, is a crying necessity for the disposal of the slop water, whether the excreta be intercepted or not. And as, in such places, provision is usually made for the removal of the rainfall by means of these water tables and underground conduits, the sewage could be dealt with on the separate system, the advantages of which are fully recognised by all those who have given the subject any consideration. On the question of separating the sewage from the rainfall, the evidence given before the Koyal Commission on Metropolitan Sewage Discharge, which sat from July 1882, to October 1884, is pretty conclusive. >Sir Robert Rawlinson says : — " If you had to begin at the beginning and sewer London de novo, the Fleet Ditch should not be a sewer; the Ranelagh River should not be a sewer; all the valley lines should not be sewers. They should have been surface water channels alone, and the sewage should have been intercepted on both sides, and carried into the main outlets which are now provided." INIr. Bailey Denton says, in his work of 1880: — "Experience has established the fact, that no mode of cleansing sewage by tank treatment, or by irrigation over, or filtration through, land, can be effective when the sewage is diluted by rainfall beyond a certain amount. It is easy enough to deal with an outflow from sewers, if the quantity be constant, and is ascertained, but it is quite beyond the powers of any engineer to devise a means of ti-eating liquids swollen by sudden and extraordinary dilution." Colonel Jones also, very experienced in sewage treatment, says: — "The Town Council of Wrexham have found it possible to meet my views, by a very inexpensive diversion of surface water from its former course (of admission into the sewers), direct into a river which intersects the whole length of the town." The Commissioners express the following opinion, in referring to the sewage of liOndon : — "We consider, however, that this is a matter of mucli importance as regards the future disposal of the sewage, in whatever way this disposal may be ettected. If it is to be used on the land, or treated chemically, its concentration and uniformity are highly desirable ; and if it is to be carried further away by a long conduit, its volume should, fiom motives of economy, be reduced to a minimum. For these reasons, the separation ought to be effected as much as possible in future extensions of tlie drainage. We are glad to see that the Metropolitan Board are alive to the necessity of this measure." Sir Joseph Bazelgette says: — "To carry out such a scheme as I am suggesting, or uny scheme suitable for those districts (the valley of the lower Thame.s), it would be necessary to separate the sewage from the rainfall. The areas are .so large, and the quantity of sewage so small, that it would be impossible to take them together ; they must be taken separately." Dr. Alfred Ludlow Carroll, formerly Secretary to the State Board of Health of New York, wrote me as follows : — " We have had in many parts of the countiy a very satisfactory experience of the 492 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. " separate system " of sewerage, wherever it is possible (as it is in most cases) to carry off surface water by surface grades. The modification in construction upon which the success of these chiefly depends, consists in the frequent and thorough flushing of them by means of automatic flushing tanks (usually Field's syphon), discharging from 120 to 140 gallons at intervals of from eight to twelve hours. A 6-inch vitrified earthenware pipe will carry the sewage of a considerable population {over 400,000 gallons per diem, with a grade of fifty feet to the mile), and is kept free from filth accumulations by the intermittent flushing." This system has been in operation in Memphis (where it was first tried), Keene, New Brighton, Rockaway, aiid other places, for some years, and so far as I can learn, has answered remarkably well, being comparatively cheap and easily worked. A complete description of the practical working of it has been furnished by Mr. Horace Andrews, C.E., in a report to the "Chairman of Committee on Drainage, Sewage, and Topograpliy, Albany. It is the invention of Mr. G'eorge E. Waring, C.E., who has recently written me to the effect that the system has been much improved of late, and is being applied to many different places in America. The "separate system" appears to me to meet the requirements of this country much more satisfactorily than any "combined system." For in the case of the latter, the conduits must be made of large size, to carry ofl" the sudden and great rainfall which so frequently occurs ; and these, during periods of dry weather, would only have a small stream of sewage flowing tlirough them, which, if undergoing decomposition, would fill them with noxious gases ; whereas, in the case of the former system, the pipes would never be less tlian half full of sewage, would be well ventilated by the means which Mr. Waring has adopted, of carrying the soil pipes above the roofs of the houses, and doing away with any disconnection between house drain and street sewer, and would be efficiently flushed as often as necessary by the automatic flusliing tanks. The disadvantages of a separate system are — that separate channels and pipes Jiave to be provided for the rain ; that the rain from all large cities carries fiom roofs and streets much organic debris, which pollutes the river or watercourse into which it may be discharged. But with a single system the drains require to be much larger, and storm overflows must be provided, sufficient to carry ofl' the storm water when the drains get filled, and with this storm water the whole contents of the sewers are discharged, so the stream would run greater risk of being ])olluted in this way, than if the surface water only were allowed to flow into it. However, the second objection to the separate system has been done away witli by an ingenious contrivance of Mr. Horace Andrews, by means of which the first portions of rain water (containing the foulest parts of the street washings, tfcc), may be intercepted, and be thus i)revented from polluting any watercourse into whicli they would otherwise run. It consists in jJacing an intercepting drain at a lowe)- level than the conduit for rainwater, and so ai'ranged that the contents of the conduit will flow into it until they increase in volume and rapidity sufliciently to shoot over the drain, by which time they are comparatively jiure. In a pajjer on "American Sanitation," by John B. Gass, A.R.I.Bd., read at the Congress of the Sanitary Institute of Great Britain, held at SEWAGE DISPOSAL. 493 York in September 1886, he says :— "Memphis is the best known and largest example of the application of the result of the investigations in various cities, by order of the United States National Board of Health. In these cities, the main sewers were gauged to determine the actual size of pipes needed for the removal of the greatest amount of foul sewage matter only, produced under various circum- stances. These gaugings show conclusively that for foul sewage matter for a large jiopulation, main di'ains of only small diameter ai'e necessary. Colonel Waring, of Newport, R. I., the engineer who designed the JMemphis sewage scheme, communicated a paper to the Sanitary Institute, in September 1880, giving a full account of this work : — "It has now been in use over four years, and the practical working appears to have been very satisfactory. To recall the main features, 1 may say that Memphis is a city on the Mississii)pi, of between forty and lifty thousand inhabitants. The main drainage system is for foul sewage only, and when complete, will have a total length of about forty miles. There being very few cellar."., and the ground having a good natural fall, the drains were laid about six feet deej). No outlet drain from any house was allowed more than four inches in diameter, the tributary mains being eight inches and six inches in diameter, and the two mains commencing from eight inches diameter and increasing to twelve inches and fifteen inches diameter, all being of socketted glazed pipes. The two mains are joined together into a twenty-inch brick sewer, which has swicches turning the drainage into a three-foot iron pipe for the high water outlet, and into a twenty-inch iron pipe for the low water outlet— the extreme variation in the river being thirty-five feet. On the main lines, man-holes have been put in at intervals. No house connection is trapped, but each has an unobstructed ventilator reaching to top of roof ; this gives vent to about thirty feet of sewer. Every slop stone, water-closet, sink, &c., has an independent trap ; hopper closets are insisted on ; the sanitary regulations are very strict ; and all plumbing work is inspected by engineers. The whole system is flushed daily or half dail}- with about one hundred and fifty Rogers Field's well-known automatic flush tanks, supplied with town water, and placed at the dead end of every branch, to thoroughly flush each length ; each flush tank discharging one hundred gallons in forty seconds, thoroughly scours the pipes. The subsoil drainage is by agricultural drain tiles one inch to three inches in diameter, laid beside sewei-, and in the same trench ; these dischai'ge into the nearest watercourse, or, on very level ground, into the main sewer, with special precautions against sewer water backing up. Storm water is removed by surface gutters, with outlets through shallow conduits, easily accessible." On this system, there have been ofiicial reports bv Mr. Gardiner, for the Board of Health, New York State ; and Mr. W\ H. Baldwin, C.E., the latter dated March 29, 1884. The following is a summary of these reports, with regard to the working: — " In the mains, from ten inches and over, a deposit is found of tine silt, supposed to be mud and paper pulp; this is cleaned out about once a month, by rope and steel brush being dragged through from man-hole to man-hole. In the lateral sewers, there are very few stoppages; when stoppages occur, they are from schools or shops only, and in pipes six inches in diameter and under, and are 494 IXTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. caused by sticks or pieces of metal getting crosswise in the pipes. For stable washings, catch pits have been found necessary. A few T clean- ing pipes have been inserted, and hand holes are now put in all extensions 100 feet apart. Some of the sewers are 2000 feet from the mains, and the longest lines generally run about a quarter full. Over- flows have had to be provided, for taking the water in winter, when the water taps are left running in the houses to prevent them freezing. Neither in removing obstructions, in cleansing the main sewers, nor in connecting with house drains, is the odour of sewer gas ever observed. This system was adopted at Keene, N.H., and executed in 1882-3. I am informed that it is working well, though the greatest fall is only four inches in 100 feet, and the lowest fall being -^-^ inches in 100 feet, and that line nearly two miles long. It is also being used in parts of Paris and other places, and may, I think, on a large scale, be considered a success." TJie "separate system" offers a very great advantage over the single or combined system, in places where the sewage has to be raised to a higher from a low level ; the quantity being nearly uniform, the pumping machinery could be easily regulated to meet all require- ments. Mr. Isaac Shone's system of pneumatic ejectors would, however, in many cases answer this purpose better than pumping. It consists in forcing the sewage, by means of compressed air from iron tanks, termed ejectors. At a central station an engine is placed, which forces air under a pressure of sixty five pounds to the square inch, into air compressors, consisting of large vessels made of boiler plate iron. From these, pipes lead to the ejectors, which may be placed at different points of the town; the distance at which they are placed from the central station being practically of no importance, as it is said, very little loss of power ensues, no matter how long the pipe may be. The ejectors are iron vessels of about 600 gallons capacity, having an inlet for the sewage which flows into them by gravitation, and an outlet for the discharge. When the ejector is full, the compressed air is admitted by an automatic arrangement, which opens the valve of the air pipe, and shuts it again when the ejector is emptied. A ball valve prevents the sewage being foi'ced back into the sewer. The height to which sewage or water can be lifted by this means is i)ractically unlimited. The town can l)e completely sewered on this principle, ejectors being placed at certain cross streets to receive the sewage of a number of houses, the sewage being forced into and along air-tight main sewers to the outfall. At Eastbourne there are seven pneumatic ejectors, which ai"e supplied with compressed air from one station, one ejector being about two miles from the station. The cost of working the system at Eastbourne, the sewage of which is entirely managed by it, is £600 per annum ; the total cost of plant, land, houses, tfcc, being .£8500. Eastbourne is, for the most part, about twelve feet below the level of high water, yet the low lying part is as well and efficiently drained by this system as the higher parts are by gravitation, the sewage being lifted sufliciently high to flow by gravitation into the sea. The mains being air-tight, there is no danger of sewer gas escaping. The disposal of sewage at the outfall is a matter of serious considera- tion, and the method must differ with the position and other circum- stances of the place. When possible, it should be discharged directly I t SEWAGE DISPOSAL. 495 into the sea, its manurial value being less than the cost of applying it to land. Its value as a manure may be gathered from the fact that, in 100 tons of sewage of average quality, the susi)ended matters are worth 2s., and the matter in solution, 15s. = 17s. in all, or about 2d. per ton theoretical value, or less than ^ of a penny actual value. Sir R. Rawlinson says : — " Sewage, to have value, must have certain natural facilities, such as cheap land and a free outlet to the sea. If the sewage of London is to be valued (at what it is worth) all the year round, you could not ])ut more than I a penny to a ton on it." Dr. Meymott Tidy says: — " The local authorities always will get it into their heads that they ought to make their sewage pay, whereas sewage is a great ugly thing that one has to spend money on to prevent its being a trouble and a cause of nuisance." Sir Frederick Abel, C.B., says : — "That it is impossible to deal with sewage in reference to its manurial value. The only real method of disposing of sewage is to carry it out to sea." In considering the question of disposal of the sewage of any place, that plan should be ado))ted which will be the least costly and most efficient — i.e., efficiency and cheapness should be solely considered, and all idea of utilisation for manui-ial purposes dismissed. Storage in Tank with an Overflow. The sewer water runs into a cemented tank with an overflow pipe ; the solids subside, and are removed from time to time ; the liquid is allowed to run away, either into a ditch or stream, or is conducted in drain-pipes half to one foot under ground, and escapes into the subsoil, where it will be readily absorbed by the roots of grasses. The fat, grease, and coarser solids, may be intercepted by a strainer, and the liquid portion may be discharged automatically by means of a flush tank (Field's). The plan is only adapted for a small scale, and when the .soil is light. It may be used for a single house, or a small village, for the slop water, even where the excreta are removed by the dry method. The tank should be ventilated by a shaft leading up a tree, and there should be a well-ventilated disconnecting gully between the house-pipe and sewer. Discharge at once into Running Water. All new works of this kind are ])roliibited in Great Britain, and the tendency is to do away with the plan altogether. The injury to rivers by turning sewage into them is of three kinds : — (1) Sediment whicli forms banks of mud ; (2) destruction of fish (fish will live in fresh sewage, but not in stale) ; and (3) emanations into the air of gases. Precipitation. The solid part of the sewage is precipitated before the liquid is allowed to pass into the stream, or over the land. This is sometimes done by subsidence, the sewage being made to pass through strainers into a settling tank ; but usually, some chemical precipitant is also used. A variety of substances have been employed as precipitants, such as lime, salts, albuminous substances, charcoal, alum, blood, clay, charcoal, manganese, &.c. ; the A. B.C. process — perchloride of iron, sulphate of zinc, permanganate of soda, ikc, and the effluent is more or less 496 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. satisfactory. Mr. Dibdin (consulting chemist to the Metropolitan Board of Works), maintains however, that the dissolved organic matter is not aiFected to any appreciable extent by chemical treatment, the sewage being merely clarified, the clearness of the effluent, i.e., the degree of removal of the suspended matter being dependent on the quantity of of such chemicals used. Chiswick offers an example of the chemical treatment of sewage, without any subsequent filtration through land, the effluent being rendered sufficiently pure to permit of its discharge direct from the settling tanks into the River Thames, above London. Lime and alum are the chemicals used, in the proportion of 11 grains of the former, to 7 grains of the latter per gallon. The lime is first mixed with the sewage by means of a revolving mixer, and the sewage passes into the pump-well, and then has a run of 300 feet before it is mixed with the alum. It is then run into tanks and allowed to precipitate for three hours, and the effluent run off into the river. The sludge is turned into a small tank at the rear of the sludge-press shed, and is then passed through a Tobinson's pneumatic sludge-press, which turns out 24 cakes, of 5 libs, each at a time, a bag of slacked lime being added to eacli lot. The sludge cakes are sold as a manure at Is. 6d. per ton. '•' Broad irrigation means," says Mr. Edward Piitchard, " the applica- tion of a minimum quantity of sewage upon a maximum area of land, l)y which we obtain the greatest amount of utilisation combined with purification, that enables the crops to be grown upon the land, at the same time that the sewage is treated, and the land purified." The land is cropped principally with Italian rye grass, but root crops, such as mangolds, turnips, &c , are also grown. The sewage water passes over and through the soil, and is thus brought under the influence of growing plants, a very good clean effluent being the usual result in the case of well-managed farms. When the sewer water passes through the soil, there occurs — First, a mechanical arrest of suspended matters; second, nitrification. — Dr. Thomas Stevenson says: — "There is no agent which so efficiently deodorises sewage as the soil, which acts not only as a checker of ])utref action, but also absorbs the gases of sewage; and further, is the nidus of the well nigh demonstrated nitrifying agents — i.e., the bacterial organism by which ammonia and nitrogenous organic matter, imme- diately, or through the intermediate stage of ammonia, are converted into nitrates." Third, chemical interchanges. — The soil I'equii'es to be deeply ploughed, or dug with a spade, and otherwise properly prepared. In the case of a light soil, ploughing will probably be sufficient; but in clay soil, underground drainage, and the a])plication of ashes or ballast (l)urnt clay) may be necessary. The land should have a gradual slope, and be levelled of all its irregularities. The sewage is allowed to flow into main carriers constructed of concrete, earthenware, or trenches dug into the ground, and from these it is carried by subsidiary carriers to different parts of the land. By a simple arrangement, any carrier may be blocked, and the sewage allowed to flow on to the ground below, and thus its distribution may bo regulated. The heavier suspended matters in the sewage are usually removed l)y passing it through strainers and subsidence tanks, the sludge being removed, and dug into the ground. By pro[)er attention to detail, a sewage farm may be managed SEWAGE DISPOSAL. 497 SO as to be free from disagreeable odours, and any danger to health. At some farms, the sewage is chemically treated, to increase the precipitation of the suspended matters. Sir Robert Rawlinson, C.B., stated before the Royal Commission referred to — "That in Doncaster 1,000,000 gallons of sewage per day were put on the surface of the ground, and that no effluent could be seen. And also in Bedford, the same quantity was put in sandy soil, with a similar result. They have discountenanced the use of tanks at Doncaster, the sewage being pumped directly into the carriers." Examples of the treatment of sewage by " broad irrigation " are to be found at Croydon — the Beddington Farm, consisting of between five and six hundred acres, receives the sewage of a population of 60,000; South Norwood, with an ai'ea of sixty acres, receives the sewage from 12,000 peo[)le ; and Tunbridge Wells, which has a population of 26,000, and the sewage of which is disposed of by two farms of 205 and 125 acres respectively. On the subject of Broad Irrigation, the Commissioners alluded to, state : — (1) That generally speaking, it offers a satisfactory mode of disposal of town sewage, when circumstances admit of its application. (2) That it offers the mo.st likely means of realising some portion of the value of the sewage. (.3) That when properly arranged, and carefully conducted, the effluent will be effectually purified ; but that under careless management, the purification will be incomplete. (4) That it need cause no danger to health. (5) That with proper care, when applied on a moderate scale, it need cause no serious nuisance to the surrounding neighbourhood; but that if improperly managed, nuisance may arise, and may become considerable. (6) That there may be a danger of the pollution of subsoil waters. Intermittent Filtration. The Croyden Rural Sanitary Authority dispose of the sewage from a population of 21,000, by filtering it through a filter-bed consisting of twenty -eight acres. The ground is underdrained to a depth of from four to six feet. The drains are twenty feet apart, and consist of six-inch socketed pipes. Grass is grown on the filter-bed. Irrigation may be combined with filtration, and chemical precijntation may be combined with either, or with both. In a paper on the " Sheffield Corporation Sewage Works," read by Mr. John Merrill, at the Congress of the Sanitary Institute of Great Britain, in September 1886, he gives the following description of the intermittent system of precipitation as in operation at Bradford and Sheffield :— " The works cover about seven and a half acres, and consist of a main building and thirty tanks, each having a capacity of 50,000 gallons, together with an oxidising weir and two filters to each tank. The process may be said to consist of four parts or sub-processes — subsidence, precipitation, oxidation, and filtration. *' The sewage enters the works, and flows through four deep subsi- ding tanks ; these act also as catch-pits, as well as separating the heavier Ik 498 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. solids contained in the sewage. The reasons for this separation of the heavier solids are threefold : — Firstly, the heavier solids form a compost •which can be readily and easily got rid of ; secondly, the quantity of sludge from the precipitating tanks is thereby reduced; and thirdly, the separation of the heavier from the lighter solids abolishes all nuisance in the drying. " From the subsiding tanks, the sewage flows forward under the main building, and receives the milk of lime. It then flows through a conveying channel, which serves also as a mixing chamber, where by a beautifully simple and ingenious arrangement, the lime is most thoroughly mixed with the sewage without the use of any machinery whatever. So intimate is this mixture, that the quantity of lime has been reduced from one ton per million gallons to fourteen cwt., a saving of about one-third. The sewage is then admitted into the precipitating tanks, which are the most important feature of this process (first introduced by M. Alsing at Bradford), and from which it takes its name of "intermittent precipitation." " As soon as a tank is full, the flow is shut off", and the sewage allowed to remain comjoletely at rest. The advantages of this method of treat- ment are very great; by it, we are able to get rid of every trace of solid matter, which cannot be done when a constant flow is maintained. " In the Shefiield Works, twenty-five minutes after a tank is filled, complete precipitation has taken ])lace, and the clarified sewage is as bright, clear, and colourless as spring water, and contains not a trace of solid matter." The next feature of the works is one entirely novel, namely, the oxidation of the eflEluent. Oxygen is the great purifier, and to quote the Glasgow report — " If an efiluent is brought into contact with oxygen, either by churning it up with air, or passing it over numerous falls, or exposing it in a thin stratum to the air, it speedily becomes inodorous, and no longer putrescable." The problem, however, has been solved in the Shefiield works, by the establishment of weii'S— one to each tank. The clarified sewage runs from the tanks in a very thin stream over a weir, with a slight fall, exposing a very large surface to the air. From the weirs, the sewage runs through two filters, downward and upward. The filters are so constructed that, after a tank is run off", the filters used can be com- pletely emptied of liquid, and allowed a period of rest, so that the filtering material becomes re-charged with oxygen. The sludge runs by gravity from the tanks into a collector, from whence it is pumped into open air drying ponds. These ponds ai-e placed at a higher level than the tanks, consequently, the supernatant liquid can be run back into the tanks, and treated over again. Mr. Merrill sums up the advantages of the intermittent system to be — " Simplicity, great efiiciency, small tank area required, economy of both construction and in working — cost of Shefiield works £32,000, and working expenses about £5000 a year." The solid excreta appear to be a great bugbear to most local authori- ties ; but their admission into the ordinary sewage does not chemically affect it, as it is well ascertained that the sewage of a non-water-closeted town does not differ chemically from that of a water-closeted one. Dr. Thomas Stevenson has stated that the composition of sewage varied I LEPROSY. i99 much less tlian luight be ex})ected, and the difference was one vatlier of degree than of kind ; that there was little difference between the sewage of a water-closeted town and a non-water-closeted town (see Lancet, May 9, 1885). The average amount per head per diem of moist excreta is, in Europe, 2^ ounces, equal to 1 ounce dry ; which, if added to 30 gallons of water — the average water-su{)ply per head per diem of London — Avould repre- sent an addition of only 15 grains of solid matter to tlie gallon — i.e., 15 grains to 10 lbs. — a mere fraction. Home provision must be made for carrying off the urine, which amounts to an average of 40 to 50 ounces per head j)er diem ; and as we now know that the bacilli of typhoid fever are to be found in the urine, it is not so innocuous as hitherto supposed. From the foregoing, it is apparent that no valid reasons exist for intercepting the solid excreta from ordinary sewage. All intercepting methods fail more or less in effecting their object. They are expensive, and contribute, in a great measure, to engender those habits of constipa- tion, which are so common among such a large section of the female population of non- water-closeted towns. LEPROSY : IN ITS RELATION TO THE EUROPEAN POPULATION OF AUSTRALIA. By John M. Creed, L.R.C.P., M.R.C.S. Member of the Legislative Council of New South Wales. It is not my intention, nor do I think it will be the desire of the Members of the Congress, that I should enter very deeply in this j)aper into the pathology and symptoms of leprosy, my object being to point out in a concise mode, the amount of danger to which a community such as that of these Colonies is exposed, by the presence in it of the few lepers which are now here. I think that only good can follow an attempt to point out how comparatively ungrounded is the unreasoning terror in which this disease is held by most non-professional persons, and to show that the danger of infection is comparatively trifling. I do not, however, for a moment wish it to be understood, that I do not think the disease a terrible one for its unhappy victims when once infected. Leprosy may affect any portion of the body. It is essentially a constitutional disorder, indicative of a cachexia, or depressed condition of the general system. Its outward manifestation occurs in three forms — the tuberculated, the maculated, and the ansesthetic. One, or all, may be present in the same subject at the same time. In lepra maculosa, the first symptoms are the appearance on the skin of spots varying in size, having an area of from half a squai-e inch, to five square inches or more. At first the colour is light red, disappearing on pressure. This by degrees gets darker, gradually increasing in intensity until it becomes Ik ? 500 INTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. a dark brown. The surface of the spot is shining and .smooth, and the skin feels like fine velvet. The latter characteristic, Hebra considered absolutely diagnostic. The affected part is not much elevated, but between the fingers the skin feels hardened and thickened, and is sometimes very sensitive. The spots are generally situated on the trunk and limbs. They grow peripherically, the centie turning into yellow brown, while the fresh outer jjortion is red and slightly swollen. They never perspire. The whole spot may disappear. In lepra tuberculosa, the nodules may grow out of the spots of the last form, or they may appear independently, they may vary in size from a shot to a walnut, they generally first appear on the face, and are almost always in the gieatest proportion on this part. The face is broadened, puffed, and brown or red in colour. On the tubercles, the hair is thin or completely lost. The nose is genei-ally thickened, and as well as the lips, covered with knots. The lobes of the ears are converted into thick, rugged masses. The tubercles may appear on all parts of the body and limbs. Next to the face, however, the hands and feet show the most striking appearance ; they become deformed ; the digits are enlarged, especially at the tips, and are frequently ke})t apart by their thickened extremities ; the joints become stiff and often immovable. The knots may atrophy, be re-absorbed, or turn into abscesses and ulcerations. Destnxction of the tissues sets in, and portions of the hands or feet may be spontaneously amputated, and death ensue after some years, according to Drs. Danielssen and Boeck, on an average in about nine or ten, though many })atients live for many years, and occasionally life is jirolonged to old age. Lepers, however, do not usually die directly of leprosy, but of diarrhoea or dysentery, of inflamma- tion of the lungs or air passages, or of disease of the kidneys. In these varieties of leprosy, neuralgia is said to be a special symptom ; but leprous neuralgia seems to be limited to the ulnar nerve, a little above the inner condyle of the humerus ; to the auricularis magnus nerve on the sterno-mastoid muscle, and to the posterior tibial nerve along its course ; but the ulnar nerve is attacked by this neuralgia most frequently and most severely. These nerves may be felt even in the early stages of the disease, when there is no neuralgia, to have assumed a tense cord- like character. Marked changes have been noted on post-mortem examination in the nerves of lepers, by Drs. Danielssen and Boeck of Norway, and Dr. Carter of Bombay, the latter's more exact observations confirming those of the former. The third form, lepra ansesthetica, is, as a rule, associated with one or both of the others, but it may occur alone. When it is the original form, large vesicles first appear on the skin, which will, probably, be mistaken for pemphigus, and for a time the sensibility of the skin remains normal, but subsequently, the seats of the vesicles lose all feeling. The anaesthetic spots may appear on an otherwise apparently healthy skin, so that patients first gain a knowledge of it by medical examination, or by the painless result of some accident, for they may burn, scald, or cut themselves without being conscious of it, except from seeing the thing happen. This insensibility is not confined to the skin, but extends to the deeper tissues beneath the anaesthetic spots. The disease may make its a])pearance at any period of life, even in early childhood, but from the age of puberty to that of maturity is the LEPROSY. 501 more general time of its incidence. Until the discovery of the bacillus of leprosy, those observers who had the best means of judging, with few exceptions, were of opinion that the disease was non-contagious ; and the numerous examples given, of continued intimate association for years, even as husband and wife, by healthy persons witii lepers, without the transmission of the disease, gave such support to this view that it was practically incontestable. The ])resence of this specific germ, however, gives such support to the opinions of those who believe that it is contagious, that I think ])robability is in accordance with this view. At the same time, the difficulty of transmission is so great, excepting under circumstances extremely favourable to the development of the disease, that there is but little danger of infection to the white popula- tion of these colonies. The long period of incubation, often many years, renders it the more difficult to decide this question positively. A case is (juoted from Borneo, in which a boy, having thrust a knife into an anaesthetic spot of a leprous child, afterwards incised with it his own thigh. He had no further dealings with lepers, but nineteen years afterwards developed the disease. Dr. Massanao Goto, a Japanese physician educated in European medicine, stated in his graduation thesis at the Cooper Medical College in San Francisco, that, by the permission of the Hawaian Government, an attem])t was made to reproduce leprosy in a convict, by inoculation with leprous matter, but that two years afterwards lie had developed no signs of the disease. According to the same gentleman, who was practising in the Sandwich Islands, and ))aid great attention to leprosy, the disease was unknown there until 1859, when it first occun-ed in the persons of two Chinese coolies; but in 1884 there were upwards of 1200 lepers, about IS per cent, of the ])opulation in this grou]) of islands; 721 of whom were, in that year, confined in the leper settlement of Molokai, and 186 in a branch hospital in the suburbs of Honolulu. About 300 more were met with by him in his private practice, who were not under Government su))ervision. In view of the fact that, in twenty-five 3'ears, the disease manifested itself in 1-5 per cent, of the population, it is impossible to deny that it must be communicable by contagion or infection ; but when this is considered, it must be borne in mind how extremely favourable for the development of the disease are the conditions of life of these people. In the Report of the Committee on Leprosy, of the Koyal College of Physicians, are given a numljer of instances, by various observers in all ])arts of the world, of the most intimate relations having existed for years between healthy ])ersons and others suffering from the disease, without its being conununicated. Dr. Goto made careful inquiry as to hereditary transmission in leprosy, and succeeded in collecting sufficient data in Japan to show that the disease occurs from hereditary trans- mission in about fifty per cent, of cases. Leprosy, when inherited from the mother, is more severe than when inherited from the father ; and is more severe when inherited fi-om both ))arents, than from one alone. The disease may skip a generation or more, to re-appear in later descendants, who have it in a milder form. This physician, as well as otlier observers, are of opinion that the presence of constitutional syphilis increases the susceptibility to leprosy, and that in those cases in ■which hereditary leprosy is latent in an individual, the infection of 502 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. syphilis will bring it into activity. He claims considerable success in the treatment of the disease, and is said to have cured several cases. The Japanese Mail says — " Dr. Arai Saku, a Japanese practitioner, who has charge of the Shusai Hospital, has been most successful in treating cases of leprosy amongst his countrymen. It is said that this was made known to the Indian Government, and resulted in their writing to Dr. Arai Saku, to invite him to go over to India, and there try his hand on confirmed cases." It must not be forgotten, that the practice of medicine in Japan is of the most advanced European type, and that its conduct is regulated by Im])erial decree as to study and qualification for practice, far in advance of the regulations in these colonies. The disease is found in all parts of the world, and under the most diverse circumstances of climate, latitude, and mode of life but in every place where it is present, the conditions of life of the people are such as to lower vitality. It is found so far from the equator as 70° north, and in such cold countries as Iceland, . Norway, the Baltic provinces of Russia, and New Brunswick ; but it is perhaps more pi-evalent in the warmer climates, and in damp, low-lying situations. In the middle ages it was common in all the countries of Europe, including Great Britain and Ii-eland, in which latter country it was prevalent until the close of the seventeenth century. The disappearance of the disease in the countries of a higher civilisation, is accounted for by the vast improvement which has taken place in the food and dwellings of the people during the last two or thi-ee centuries. Prior to this, for at least six months of the year, the entire animal food of the population consisted of salt meat or fish, often in a semi-putrid state ; whilst wheaten bread was an unknown luxury to the majority, and fresh vegetables were unprocurable, except in the summer months. The dwellings were unventilated and often filthy in the extreme, the I'ushes or straw with which the floors were strewed being frequently left until they were rotten before removal — this insanitary condition being added to by the debris of food dropped or thrown down by persons eating. Personal cleanliness was almost an unknown thing in those days, no greater proof of which can be advanced than the curious fact brought into prominence by " Saint Beuve," in a review of the diaries of the physicians of Louis XIV. of France. Of this monarch it is recorded, that after childhood he took but one bath, which he found so distasteful, that he vowed he would never take another ; and it is believed he kept his word. When such a thing is recorded of so great a personage — the head of the most refined court of Europe at a comparatively late period — what must have been the condition of the lower classes during the time in which leprosy was prevalent on that continent. Even in the great houses, men slept on straw in the large hall, often with a common covering ; whilst clothes were made of such lasting material, and were so passed from one to another, as must have greatly aided the transmission of disease of all kinds. These clothes it must be remem- bered were worn, by at all events the lower classes, without body-linen. As to the conditions under which le[)rosy exists in these times, we have the fullest information in the answers to the interrogatories put by the Committee of the College of Physicians, of London, who made inquiry some twenty-five years since. Almost without exception, the answers show that the disease rarely attacked any but persons living LEPROSY. 503 under conditions of the most insanitary kind; and that in the majority of instances, it showed the greatest activity where the diet consisted principally of salt tish, often semi-putrescent, with dry vegetable food, mainly consisting of inferior and damaged gi'ain ; and that in those places where the patients had had a fair supply of fresh meat, there had been a complete absence of fresh vegetables. In Hawaia, where the spread of the disease has been more rapid than anywhere else, the staple diet is chiefly vegetable, with fish ; the former is generally prepared so as to be in a fermented or even partially putrid state before being eaten. Dr. Thomson^ surgeon to the 58th Regiment in 1853, accounted for the presence of leprosy amongst the Maories by their neglect of personal cleanliness, and their fondness for putrid vegetable food. He says that the disease was more common just in proportion to the fondness of the people for this kind of diet. He remarks that " since the improvement in the condition of the New Zealanders by intercourse with Europeans, the disease is becoming rare." In Australia, in 186-5, there were no known lepers, except in Victoria, which at that time had thirteen. To the present time, there have been none known in South Australia or Tasmania, and the number has decreased in Victoria to five, but there are now ten in New South Wales, and several in Queensland — the exact number I have been unable to ascertain from the health authorities of that colony. The lepers in the older colonies are all Chinese immigrants, with two excep- tions — one of whom is a Malay, a native of Java ; the other a young European, aged twenty-seven, born in Sydney. The latter is, as far as I can ascertain, the only instance of a white leper known in Australasia, except the young daughter of a British oflicial in a South Sea island. His is a well-marked case of the tuberculated variety, but little informa- tion can be obtained from him as to the probable source of his disease. He, however, denies all intimate association with the Chinese. To summarise, I submit we may fairly assume : — (1) That the disease is contagious, but only under circumstances (extremely favourable to its propagation) which lower the vital powers of the persons exposed to it ; and that there is no real danger to persons who live with good sanitary surroundings, have a fitting, wholesome diet, and are personally cleanly, however intimate their association with the lejjer is. (2) That the disease may be hereditary, but frequently skips genera- tions, and becomes less severe as the descent becomes remote. (3) That the presence of constitutional syphilis increases the liability to the disease. (4) That though very intractable, it is not incurable, and that cases improve under treatment ; and there are occasionally instances of spontaneous cure. (5) That there are other diseases much more dangerous to life and health rife in these colonies, and that there is no just reason for the unrea.soning dread and horror in which leprosy is held by the majority of the people. 504 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. SHORT ACCOUNT OF THE CLIMATOLOGY OF NELSON, NEW ZEALAND; AND THE DISEASES FOR WHICH IT IS MOST SUITED. By J AS. Hudson, M.B. Lend. The town of Nelson is situated at the head of Blind Bay, in about 41 J parellel of south latitude, almost exactly the same latitude as the City of Wellington, and right in tlie course of the westerly winds ; yet, while Wellington is so windy, that it is often spoken of as the " City of Blow," Nelson is comparatively free from wind. The reason for this is seen in the disposition of the Mountains. The main range of the Southern Alps, the backbone of the Middle Island, about eighty miles south of Nelson, splits, roughly speaking, into an eastern and western range. The former is continued thi-ough the Spencer, St. Arnaud, and Raglan Ranges, Gordon's Knot, Ben Nevis, ikc, into those lower ranges which tei'minate about the Pelorus and Queen Charlotte Sounds. The latter (i.e., western) is continued through the Brunner, Lyell and Owen Mountains, and the Mount Arthur Range, to the gradually lessening declivities, which terminate at Separation Point and the Farewell Spit. Between these ranges, lie Nelson and the shores of Blind Bay. The effect of this is, that easterly, westerly, or southerly gales are to a great extent deflected, and blown over the town, leaving the lower atmosphere comparatively still. A striking demonstration of this fact may be frequently observed on moonlight evenings, when the clouds may be seen travelling o^'er the moon at a consideral)le rate, while the lower atmospliere is absolutely still. The nights of Nelson are usually still ; spring is the most windy season, and winter the least so. The most characteristic winds of Nelson are — tirst, the sea breeze ; and second, the Waimea wind. The direction of the first is northerly, and generally accompanies fine weather. la summer, it usually commences at about 9.30 or 10 a.m., and blows strongly until sunset, reaching its maximum force at about 2 to 3 p.m. At niglit, and early morning, there will be a slight land breeze from a S.S.E. direction. In winter, the sea breeze is a very gentle zephyr, commencing about noon, and blowing very gently until about 4 p.m., soon after which the sun sets behind the we.stern hills; and the consequent sudden fall of temperature, say between 4 and 6 p.m., is one of the most trying features in the Nelson climate. Invalids with delicate chests should beware of that period (4 to 6 p.m. in winter), and always arrange to be in the house. After 7 or 8 o'clock, there is much less danger of exposure, for then the atmosphere has in great part deposited its moisture, and is consequently much dryer, and less irritating to the bronchial mucous membrane. ACCOUNT OP THE CLIMATOLOGY OP NELSON, NEW ZEALAND. 505 The Wainiea wind is S.W. in direction. It is a cold wind in winter, for it blows ort' the then snowy mountains ; but a hot, dry, dusty wind in summer, for then it comes from over the parched-up hill.s. It usually does not commence until about 9 a.m., tlien blows hard all day, winter or summer, and usually dies away about .sunset, though occasionally it will continue titfuUy blowing all night. It is produced by a combination of the general westerly wnnd (all over New Zealand) ; and locally, by the sun heating the low lands round the shores of the bay, and so raising the atniosphere — and the colder air from the mountains rushing in to supi)ly its i)lace — in fact, a sort of reversed sea breeze, only it will not occur except there be a westerly wind blowing over this part of New Zealand. It is the driest wind we have, and is always indicated by the hygrometer showing a large ditterence between the wet and dry bulbs. To give an instance — on January 2, 1888, aWaimea wind was blowing; at 10 a.m. the dry bulb stood at 81, the wet at 62, indicating a dew point of 40'6, and a relative humidity of 23, taking 100 as saturation. That was the hottest and driest day we have had this year. Our coldest wind, and at the same time most bracing, is the S.E., this is generally squally, and not unfrequently showery ; and if ever we get snow in Nelson (which is extremely rare, only once did a few flakes fall within the last eight years), it comes with S.E. weather. S.E. winds are most prevalent in the early spring. Our rainy wind is the N.E. A typical Nelson rain comes on something like this — you may notice a bank of cloud along the northern horizon, and clouds more or less piled up over the eastern and western ranges ; a damp northerly breeze begins to blow, this increases in force, at the same time getting warmer, and then down comes the rain, accompanied with much wind at first. Gradually tlie wind lessens, the rain comes down straight, and then, if you notice the sky beginning to get lighter over the N.W., you may pretty certainly pio})hesy the rain will soon cease. Our rainfall avei'ages from 30 to 40 inches per annum ; in 1887, it was 29'04 ; and in 1888, up to the present time (December 11), it has amounted to 26'38 inches. Comparatively little rain falls during January, February and March, the rest is ])retty equally distributed throughout the remaining nine months. North westerly winds are damp and warm, they often blow with great violence and cause high tides ; tli^y pile up a tremendous quantit}^ of mist on the south back hills, and give the appearance of a heavy downpour, but we never get more than a .shower with N.W. weather. After a short time the wind usually changes to S.W., and all the mist on the hills rapidly disaj)pears. 506 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. -noi^uoo JC|.rB9a JO 's n o n n 1 'J -noD JO sXv(j }o jaqron^ tptqiv uo e.fuQ JO jaqraiiNi t-C-OOiOt-IMOOfHCOOieOCl OOO QOC-a>«p05CO»H lo o o ^- oj 6 CO CO (M CO 'f aa -^ ;:r ^ ^ , ^ rO O ^1 CO — . ^ — ^ ^ ,— . -^—r-r-* q2 oi 5x5c?5 . .o3 2 a^ a^ 3° s -* ^ 00 . cp^-•N(^l cp50 mhcoioco-^i-hio t^«s t^-eo ih us t(*' ;^t-(jadbo 6«b rHTH65lOlAJO^-?2a>6■J5§g^.co5T"^ ^'^O'c *" »« o CO t- t^to ?o »o -s< Ti( ^ m o '^ o w '^ ^ >o MS ^ -"^ us"'»05 00 - :ao : ; :: r s-a-^^^. aS'aaS' oJ'^as-^'^-Sopoa .is > o g .a - 5; CL,.s >■ " a r^ J;; 0) .^ iM'^ •c t->S >.& ^ 2 « ^ s^ ■S a 0^ a a S 2 'H s&^s^ a oj o fc ACCOUNT OF THE CLIMATOLOGY OF NELSON, NEW ZEALAND. 507 The chief characteristics of the Nelson climate are: — (1) Stillness of atmosphere. (2) Dryness of atmosphere. (3) Equality of temperature throughout the year. (4) Large proportion of bright sunshine. The first point I have already touched upon. The second is strikingly shown by the almost entire absence of fogs at the sea level, and for almost 500 feet above it. During the eight and a half years I have been I'esident in Nelson, there has only been one foggy day (of course I mean white mist, not yellow London fog) ; this occurred in July 1885, and cleared up towards evening. I think this is the more remarkable, as in certain interior districts of Australia, which are at the same time much hotter and drier than Nelson, are subject to fogs, at any rate, in the winter months. For instance, I liappened to be staying at Goulburn, N.S.W., for a few days in July 1886, and although it was tine weather, the fog was very dense until about 10 or 11 a.m. This is a most important factor in the suitability of Nelson for consumptives. Of course I am speaking of the lower strata of atmosphere ; mist on the hills is of almost daily occurrence. The average relative humidity of Nelson is about 70, taking 100 as saturation ; and as might be expected, the summer months, January and February, are the driest ; and the winter months, June and July, the dampest. Third — Equality of temperature throughout the year. — This is a striking feature in the Nelson climate. The average day temperature, taken at 10 a.m., varies from about 45*^ in July to a little over 70° in January. I have taken the temperature carefully for the last three years (at 10 a.m.), and the highest of which I have any record is 81° on January 2, 1888, and the lowest is 37°, in June. These are day temperatures. On winter nights, the thermometer will sometimes fall to 25°, when fully exposed on the grass ; and even in summer the nights are always cool. The temperature usually rises slightly after 10 a.m., but not much, for the sea breeze usually sets in about that time, and the warmer the day the harder it blows, and so keeps the temperature from rising much. My thermometer is placed under a verandah, facing the south, and I have never known it reach 90° at any time. The summer minimums range from 40° to 55°. Fourth — Amount of sunshine. — Bishop Selwyn, long ago, drew attention to the sunny skies of Blind Bay ; and, although very many parts of Australia and Africa can show a larger record in this respect, still, taking into consideration that Nelson is excellently supplied with water for all household purposes, and that there is plenty of rainfall for agriculture, it is perfectly wonderful the amount of sunshine we get. I find, from my observations, that out of thirty-two months, containing in the aggregate 973 days, there were 550 days of continuous, or nearly continuous (i.e., days on which the total obscuration did not amount to an hour), sunshine. During the same period there were 283 days (i.e., 24-hour periods) on which rain fell. These must not be considered rainy days, as in many instances the rain fell in the night, and even if it only fell for ten minutes, it would be recorded in my observations as rain having fallen on that day. The nights in Nelson are never very 508 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. hot ; no matter liow oppressive the day may have been, the nights and early mornings are always cool, and feel like a pick-me-up. We now come to the considei'ation, most interesting to our profession, of the diseases this climate is suited for. Foremost in the list stands consumption. My eight and a half years' experience enables me to sj^eak very confidently on that point; and I can assert without any fear of contradiction, that almost every case of consumption, contracted in a cold damp climate like England, will be considerably benefited, and life much prolonged, by a residence in Nelson. This has been observed time upon time, and I will now give a few details of individuals known to me personally : — J. G., a young man, came from England two years ago, with con- siderable disease in both apices, pyrexia, quick small pulse, &c. He rapidly improved in every way, and now rides and walks just like any other man, attends meetings at night and in all weathers. I have not examined him lately, but see him constantly about the town. W. S., a medical man, came from home with phthisis considerably advanced. He was able to follow a large general practice for over ten years, including plenty of night work. During this time the disease never advanced, and he became quite stout; but unfortunately, while in liis usual health, he was seized with an attack of htemoptysis, due to the old disease, and he expired within a fortnight. W. B. G. contracted apical pneumonia in India, in the early part of 1880. This was followed by plithisis, for which he went to England, and spent the winter of 1880-1 at Davos Platz, where he derived very much benefit, so much so that he ventured back to India ; but finding that he rapidly relapsed, he returned to England, and came out to Australia about October 1881. He now lived for some months on a sheep station in the interior of N.S.W., but finding the lieat too great for him, he came to New Zealand in the early part of 1882, and lived for some months at Tauranga, in the Bay of Plenty. Not feeling satisfied with his progress, he removed to Nelson in August 1882, where he remained under my care for three years. During this time he was a valetudinarian, but kept tolerable health ; however, he was not satisfied with remaining about the same, he wished to get well, and remembering how very much benefit he derived from residence at Davos Platz, lie decided to try the mountain climate of Colorado. There, however, lie was very unfortunate; he broke his arm, he had an attack of luemoptysis (this latter symptom he never suffered from in Nelson), and about a twelvemonth ago, I heard of his death at Colorado Springs. "W. T. sliowed symptoms of incipient phthisis about twenty-five years ago; since his ai-rival liere he has married, bi'ought up a family, and lives just like any otlier man. Of course we get cases of consumption develop here in people born in the district, and occasionally in those who have come out from Great Britain, free from the disease ; for these, of course, continued residence in the climate is useless, and I always recommend such cases to either try the dry interior of Australia or South Afi-ica, and better still, the mountain climate of Colorado. Cases of clironic bronchitis, contracted in Great Britain or any similar climate, derive great benefit in Nelson. We have here, among us now, an eldeily F.H.C.S., who four or five years ago was brought THE COLONIES AS A IIEALTII RESORT FOR CONSUMPTIVES. 509 very low indeed with tliis iiialaily, combined with a weak heart. He was ordered to Nelson, and since his arri^"al here has enjoyed unin- terrupted fair health ; attends evening meetings, itc, and goes about just as any other individual. Asthma is such an erratic disease, that it is impossible to say whetlier it will be benefited or not by a i-esidence in Nelson. The Nelson climate also appears to be suitable for people more or less broken in health by residence in the tropics. AVe have now, and always have had, several old Indians living amongst us; one I can think of now, who has been a victim to gout and rheumatism for several years, tinds this climate suit him better than any he has tried yet. The weak point in Nelson, as in so many colonial towns, is its drainage; this is gradually impro^■ing year by year, but is far from perfect at pre- sent — not that the town presents any insuperable difficulties in the way of drainage, and we have enough available water to flush a sewer ten feet ' in diameter, continuously all the year round — but the sewers have been constructed by difterent men, having different ideas, and none of whom have been qualified to write C.E. after their name. To this flaw, in an otherwise almost perfect climate, may be attributed the fact, that we are more subject to epidemics than we ought to be. The principal ones that have occurred since I arrived in May 1880, have been : — An epidemic of pneumonia, in September and October 1880; of measles, in 1882; whooping cough, in 1882; dysentery, in 1885; influenza, in the spring of 1887; and diphtheria, in the winter of 1888. With regard to this last, the majority of the cases were traceable to direct contagion. Occasional cases of typhoid fever occur, but I think, leather less frequently than I observed when practising in a rural district of Norfolk, England. Our comparative freedom from typhoid fever I attribute to our excellent water supply, of which every Nelsonian is justly proud. The water supplied is perfectly pure, and practically unlimited. Our food supjily is, in common with the rest of New Zealand, good, varied, and abundant. THE COLONIES AS A HEALTH RESORT FOR CONSUMPTIVES. By J. Carnegie MacMullen, L.R.C.S.T., l^c. Late Honorary Surgeon, Auckland Hospital, New Zealand. The subject of consumptives travelling to, and sojourning in, these colonies, is of such great importance, that I wish to make some remarks upon it, from the time such sufferers leave Great Britain, until they recover, return, or die. In the flrst place, it would appear that medical men in the old country, having exhausted the usual remedies, advised change of air, regulated diet, etc., and finding no improvement in their patients, at last come to the stereotyped " sea voyage," with or without i-esidence in the colonies " somewhere." They do not, as a rule, seem to have any special knowledge as to the suitability or otherwise of any 510 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. particular locality ; and so little do tliey seem to know of the colonies generally, that a patient is frequently told to go to Australia or New Zealand, no advice being given as to what part of either will be likely to suit him. He may be roasted in Queensland, or frozen in Tasmania ; be exposed to the intense cold and inclemency of Southland, or enei'vated by the moist warmth of the north of New Zealand. He is not told to go inland, or to the sea ; to remain in a town, or seek the country. If he can only be got away, he may crane over an office desk, idle about town, going to hot theatres and crowded balls ; or, if he be fortunate enough to receive competent advice, he can live a wholesome life in a suitable place, provided he can alford to do so, in which case, if his lungs are not seriously damaged, he has a good chance of getting well. With regard to the sea voyage, if a patient has advanced phthisis, I • do not think he should be sent upon a long sea voyage with a view of re-establishing his health, for the vast majority of cases show that death is the usual result ; and I would here quote a few passages from the valuable work by Dr. Wm. S. "Wilson, of Sandown, Isle of Wight, on " The Ocean as a Health Resort"' (J. and A. Churchill, 1881). He says, at page 14 : — "Consumption is the illness of all others for which it is now customary to prescribe a sea voyage, although it is only compai'atively of late years that this has been the case. There can be no doubt that, in the first stages of consumption, a judiciously selected sea voyage is often of incalculable value — the one great point is to take the disease sufficienthj early, if possible when the first threatenings only have manifested themselves. Every physician is familiar with cases where, while the patient is still young and the constitution otherwise sound, symptoms arise which, though they might be regarded as trivial by the patient himself, will be at once recognised by the medical man as of grave import, especially if there should be any family predisposition to lung disease. These are, in fact, the premonitory symptoms of what may prove serious pulmonary mischief. It is in just such cases as these that a sea voyage acts most beneficially. It will often eradicate the tendency to consumjDtion, and establish the con- stitution for life. Even in those cases w-here the first stage of the disease is more fully established, a few months at sea will frequently arrest the mischief, and sometimes effect a permanent cure. It is when tlie disease has passed into its later stages, that the advisability of sending a consumptive patient to sea becomes more doubtful. Even then great benefit will sometimes be obtained; but the question whether the possible good which may result, will weigh against the certain loss of home comforts, and the many inconveniences of ship life, is one that can only be decided by the physician in attendance on the case." Even for those sliglitly affected, it is not good to travel in a noisy ship, for it is anytliing but beneficial for a consumptive person to make one of three or four in a small ill-ventilated cabin, putting aside the danger, which is far more tlian a mere possibility, of his imparting the disease to one or more of his companions, especially should any predisposition exist amongst them. A sailing ship, or auxiliary screw steamer, should be chosen, large and well provisioned, liaving plenty of accommodation, good ventilation, and properly warmed in cold weather. Tliere should be on board a THE COLONIES AS A HEALTH RESORT FOR CONSUMPTIVES. 511 large airy and well-appointed liospital ward, to which patients suffering severely from any form of disease might be removed, both for their own sakes, and for the comfort and well-being of their fellow passengers. (Valuable information on the subject of ventilating ships' cabins, &c., is given at page 330 of Dr. Wilson's book.) On arriving at any port in the colonies, if intending to remain for any length of time, the patient should consult a physician (say the Health Officer of the port, who should make it his duty to be well infoi'med as to the various localities and climates likely to suit his case) as to where and how he should live; and should he have arrived at any unsuitable place, be advised to seek some other moi'e likely to benefit him. If the circumstances of a patient make it necessary for him to engage, on arrival, in office-work, or other unsuitable employment in a large town — placing himself more or less under similar conditions to those he has just left — I do not think he can improve, and would have been better advised to remain where he was. As to the main question of the colonies as a health resoi't for consumptives, I do not wish to extol one place as being better than another, although certain parts are, no doubt, to be avoided. There are parts of each of the colonies which are eminently suited for those suffering from pulmonary disease, but they must live in those places under certain healthful conditions conducive to recovery. They should live in a comfortable house, well ventilated, warm in winter, and cool as possible in summer. Their food should at all times be varied, and of the best quality. There should be ample supplies of fresh milk, butter, eggs, and vegetables. The question of stimulants should be decided in each case by the medical attendant, both as to kind and quantity allowed. Smoking should be limited, and clothing carefully selected to suit the climate. The patient should live in the open air as much as possible, but never over-fatigue himself. Riding, dinving, shooting, fishing, and any other healthful occupation or amusement, will greatly benefit him; but excesses of any kind must carefully be avoided. Under such circumstances, I feel confident that many would recover who otherwise would go from bad to worse; but the difficulty lies in placing such conditions within reach of those requiring them. Many are fortunate in having friends on home stations and farms, where all the necessaries I have mentioned can be had. But there are so many who must work to live, that the question is rendered very difficult of solution, and it is mainly with tlie object of raising discussion on this point that I have brought the subject forward, and in order that, if possible, the question should he represented in such a light, that more care and discrimination may be exercised in the selection of patients sent to Australia and New Zealand for their health, thus also avoiding discredit being thrown upon our colonies as a health resort. We frequently see patients far advanced in phthisis, who have been sent from home l3y their doctors, having been told that there was a good chance of recovery. Huch a case came into my hands quite recently. A gentleman from Glasgow arrived by sailing ship at Auckland ; he had been sent away without friend or servant to accompany him, and assured that he had a good chance. He was one of three in a cabin, and the ship was ill-provisioned. On arrival, he was in a dying state, though not much worse than that in which he 512 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. started. I managed to keep him alive for a few weeks, and then sent him back, hoping he would see his wife and children again before he died. Anyone could have seen that when he left home, his case must have been a hopeless one, and yet he was sent away without a friend to cheer, or servant to help him, in a comfortless ship, to spend the last few weeks of his life in misery, a stranger in a strange land, and to die without the sympathy and kindly offices of his family, none of whom he was likely to see again. Cases of this kind are of such frequent occurrence, that I think it our duty to lift our voices in strong protest against the practice of medical men at home sending such cases away at all, and to beg of them to use all care in considering the circumstances, both physical and financial, of any patients they may advise to seek for health in the colonies. With regard to the difficulties to be met liere in giving patients the best chance of recovery, T would suggest the possibility of selecting suitable localities for health establishments, and there having large farms with cottage dwellings, where patients would live as in their own homes — two or three friends in one house, a family in another, &c., &c. Servants could be procured as required through reliable agents. A manager would supervise the working of the farm, and the general well- being of those living on it. Horses and vehicles could be kept for hire, and fruit, ikc, grown on the farm, could be purchased by the patients. Sheep, cattle, pigs, poultry, etc., could all be raised on the farm. In conclusion, I would again refer to the great danger to healthy persons from sleeping in small apartments, and for lengthened periods, with those wlio are suffering from advanced phthisis. Recent scientific research has shown conclusively that, under such circumstances, phthisis is undoubtedly communicable. It is therefore our duty to warn the public who are unaware of the fact, which I do not think is sufficiently recognised even by the profession. My hope is that discussion on this subject will lead to some practical steps being taken for the benefit of the healthy public, for consumptive travellers, and the phthisical portion of our population, which is not by any means inconsiderable. SOME OBSERVATIONS ON THE WESTERLY WINDS OF WINTER IN THEIR INFLUENCE ON DISEASE. By F. MiLFORD, Sydney, N.S.W. In the winter of the year 1851, when a student at the Sydney Infirmary, now the Sydney Hospital, the late Dr. Douglass, one of the honorary physicians, drew the attention of the other pupils and myself to the important fact that, "during the prevalence of tlie present strong westerly winds, the tongues of patients suffering from inflammatoiy disease have been dark -colovx red and dry." Since that period, when I have liad an opportunity of obser\ing, and during tlie last thirty years tliat T have Ijeen in practice in Sydney, I have found the epidemic constitution of the year influenced considerably by the presence or WESTERLY WINTER WINDS IN THEIR INFLUENCE ON DISEASE. 513 absence of these sti-ong winds. As a rule, these produce a depressinir influence on the nervous system of persons sufiering from disease, and robust healthy persons are more subject to assume zymotic disease at these times than at others. Intlanmiatory attacks of a sthenic character, during the prevalence of these winds, in some cases rapidly become asthenic, typhoid symptoms supervene, the tongue becomes dry, hard and brown, tlie temperature elevated, the pulse rapid and small, and the patient delirious. So much has my practice been influenced by the presence of these winds, that I have been in the iiabit of postponing any surgical procedure, not ab.solutely necessary, until such period as the westerly has blown itself out — perhaps two or three days, or even more. As a rule, westerly weather prevails during the winter months, but occasionally a whole winter may pass without strong gales from this (quarter. The westerly wind is more prevalent during April, May, June and July, than other winter months. It may blow directly from the westward, or southward, or northward, varying sometimes three or four points during the day. ]Mr. Thorpe, of Brisbane, in the year 1880, read a paper before the Queensland Philosophical Society on these westerly gales, which was afterwards printed in pamphlet form. Through the courtesy of Mr. Lenehan, Assistant Astronomer at the Sydney Observatory, I ha%'e recently had the opportunity of perusing it. He ascribes the origin of most of the westerly gales of our winter months to an inrush of cold air from the Southern Pole, which at tirst blows directly from the south, and gradually curves round so as to blow from the west. After arriving at between 35° and 25°, the gale alters its direction to the westward, or a few points to northward or southward of it. Shortly before the westerly conmiences, the barometer falls considerably ; is seen to be often as low as 29° 50', and I have seen it as low as 29°. The gale during the first twelve or twenty-four hours frequently blows at a velocity of from fifteen to twenty miles an hour, and sometimes assumes a rapidity of from forty to fifty miles. This wind is usually very dry ; caused, according to Mr. Thorpe, by the deposition of the moisture originally contained in its atmosphere during its passage along the southern coast of South Australia and Victoria, and the inland districts to the .southward and westward of Sydney and Brisbane. During the pre^■alence of the wind, the barometer gradually rises, the sky is per- fectly cloudless, the temperature in Sydney varying from 48° to 62°. We learn also from the Government Astronomer's report (Mr. H. C. Russell), that the amount of ozone in the atmosphere is less than during the prevalence of easterly, north-easterly, and south-easterly weather. From tables most kindly furnished me by the Government Astronomer, I have been able to draw up a resume of the various p^e^'ailing weather which has occurred in Sydney during the first eight months of 1888:— During January, the most prevalent direction of the wind was easterly during thii*ty days. The greatest velocity was from north-east or south-east. On thirteen days out of the month, there were some periods during which westerly airs prevailed, but there was only one day in the month when its greatest velocity was from a westerly iL 514 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. quarter; this was the 15th, and the wind was S.S.W. The mean' temperature of the month was 70° 8' Fah. In February, twenty-two days partook of westerly weather, although in two days only was it the prevailing wind, i.e., on the 10th and 24th. Mean temperature was 64" 9' Fah. In March, there were no less than twenty-seven days which partook more or less of westerly weather, and in thirteen it was the prevailing wind. Mean temperature 67° 7' Fah. In April, twenty-seven days partook of westerly weather, but only eight in which it was the prevailing wind. Mean temperature 64° 9' Fah. In May, the wind blew eveiy day from the westward more or less, and there were thirteen days in which it was the prevailing wind. Mean temperature 56° 1' Fah. In June, the wind was more or less westerly during the whole of the thirty days, and during twenty-three days was the prevailing wind. Mean temperature, 55° 7' Fah. In July, the whole thirty-one days showed w^esterly weather prevalent, with the exception of a few hours during nine days and two days (the 7th and the 11th), when it blew strongly from S.S.E. and S.E. respectively. Temperature, 53° 5' Fah. In August, there was more or less westerly weather during the tliirty-one days, and sixteen days out of the thirty-one days it was the prevailing wind. The mean temperatui'e at Sydney was 54° 5' Fah, With the exception of the direction of the winds, their force, the barometric pressure, and the temperature, the hygienic conditions of Sydney did not alter, although we find from the Registrar-General's returns that deaths from diphtheria increased from March to July, The deaths recorded from this cause in Sydney and suburbs dui'ing the first months of the present year are as under :— Deaths in Sydney and Suburbs. May 15 June . . . . . , 12 January , . . . . . 5 February . . . . . . 7 March , , . . . . 6 Amil 11 JiUy 17 August . . . . . , 10 It will thus be seen, that the deaths from diphtheria increased and decreased in the same ratio with the duration and strength of the westerly winds. As a rule, catarrh and influenza are more or less epidemic during the prevalence of these westerly winds. These are caused, not only by the retardation of the circulation, occasioned by abstraction of heat from the cuticular surface of the body, contraction of the capillaries, and congestion of the vessels in tlie internal organs, but also by the irritating natui'e of the cold dry air itself, brought into contact with 'tlie mucous membranes of the nose, mouth and throat, as well as the lining membranes of the larynx, trachea, and bronchi. This is, in my opinion, one of the most predisposing causes of diphtheria. I have known at least three rapid deaths result from exposure to westerly winds during the months of May and June in the tram carriages, the persons thus dying being, in two cases, healthy nursing mothers ; and in the third, a healthy old man of eighty. The cause of death in these cases Avas congestion of the internal organs, especially THE MEDICAL PRACTITIOXER AX OFFICKH OF THE STATE. 515 the lungs and kidneys. The persons most likely to suffer are those who have a tendency to chronic bronchitis, or are affected with incipient or miliary tuberculosis of the lunleasure of meeting Dr. Wigg, I heard he was going to combat principally the remedy against rabbits, and the treatment of hydrophobia. I mark with pleasure, that Dr. Wigg does not intend to attack Pasteur's work on Cumberland Disease, and its vaccination — a discovery now universally adopted, which no one doubts, and the efficacy of which Drs. Germont and Loir have shown in such a conclusive way a short time ago in New South Wales. 536 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Firstly, as regards Pasteur's remedy against the rabbit pest, I regret that 1 have not time to complete any long and scientific work, or to look up all the documents aboiit the microbe of chicken cholera, that I would like to give you. Also, I cannot here undertake a technical discussion. I cannot however accept, and I must protest, when I am told that the experiments made in Australia are a failure, when they have succeeded a number of times all over the world. After waiting and talking for six or seven months, these experiments were at last allowed to be made, and everyone has in mind the success which The Argus recorded. All the rabbits on the small island on which the experiments were made, were destroyed, whilst none of the other animals contracted the least indisposition. The disease produced is so little contagious, that Drs. Germont and Loir offered to eat the flesh of some animals inoculated with this microbe. The contagion affects rabbits, and in no way does it afiect other animals. It was said that birds were liable to take it. This has not been proved, at any rate in the case of fowls. Does it not remain a fact, that the rabbits were destroyed, as was announced ? Why are complementary experiments not undertaken? For more than eight months Pasteur's delegates have been here, ready to perform all the experiments which they may be asked for, and certainly quite willing to try and convince all who have doubts. Secondly, in reference to hydrophobia. — I have here sufficient proofs to convert Dr. Wigg, and I hope he may be convinced. I do not argue, but bring figures and facts. That recovery from hydrophobia does occur, is everywhere admitted. The most incredulous have, after a careful study, been convinced, and there are now branch establishments of Pasteur's Institute in nearly all parts of the world. There is only one celebrated detractor of Pasteur — Professor Peter. Dr. Wigg has read Peter's criticisms, which are based, on I do not know what statistics, which have been falsely given. I regret very much that Dr. Wigg is not in possession of all the discussions which took place at the Academy of Medicine of Paris on this subject, and at which Peter's arguments were completely and surely destroyed, one after the other, and himself reduced to silence. In one or other of the many and keen scientific discussions that have taken place on this subject, every argument has been employed for and against anti-liydro])hobic vaccination — its adversaries declaring it useless or dangerous ; its partisans pro- claiming it inoffensive and wonderfully useful. The battle, after being stopped for some months, was resumed in Pasteur's presence, when presenting the report of the English Commission to the Academy. This official commission, composed of the first scientific men of England, and of a young and clever physiologist, Mr. V. Horsley, as reporter, went to Paris full of incredulity. After a careful inquiry into the facts, this commission returned to England, and repeated Pasteur's experiences for more than a year ; the conclusion being, to the great disappointment of his adversaries, that " M. Pasteur had discovered a ])reventive method for hydrophobia, comparable to that of vaccination against small-pox." This is a quotation from their report ! There are now in the world more than twenty anti-hydrophobic institutes. Besides those in Paris, there are seven in Russia: — Odessa, St. Petersburg, Moscow, Varsovia, Charkow, Samara and Tifflis, and five A NOTE ON Pasteur's methods. 537 in Italy : — Na])les, Milan, Turin, Palermo and Bologne (these last two recently created and endowed by the King). There is one in Vienna, one in Barcelona, one in Bucharest, one in Buenos Ayres ; and, to conclude, in Chicago and Malta two new laboratories are being organised. The Anti-hydro})liobic Institute of Paris is in constant relation with all these laboratories, the directors of which have all studied Pasteur's method at Paris, so as to apply it to their patients with all its jn'ogressive improvements. I will now give you the official statistics of the Pasteur Institute since its opening, as embodied in the report which was read before the President of the French Bepublic, at the inauguration of the new Institute : — From the lirst, the patients have been classified in three classes, A, B, C. The Class A contains all the patients v iiich have been bitten by animals, known by certain proofs to be absolutely mad. In Class B are those bitten by animals stated to be mad, by certi- ficate from veterinary surgeons. It is the frame the most filled. Lastly, Class C is for patients bitten by animals supposed to be mad. Suspicion here is based on the circumstances of the accident. The number of people treated in Paris, in the years 1886-1887, and for the first half of 1888 is 5374. In 1886, when strangers were numerous, there were 2682 people inoculated, 1778 people in 1887, and 914 up to the 1st July, 1888. The mortality, counting all the deaths, including even those taken ill the day after treatment is — For 1886, 1-34 per cent.; for 1887, 1*12 per cent.; for 1888, 0-77 per cent. Foreign statistics are in accordance with those of Paris. In St. Petersburg, in the laboratory founded by His Imperial Highness, Prince Alexander of Oldenburg, and endowed by him, there have been, from the 13th July, 1886, to the 13th September, 1888, 484 patients; the mortality numbering 2 '68 per cent. From information given by Dr. Kraiouchkine, this mortality is explained by the extreme gravity of the bites. In Odessa, in the laboratory managed by Professor Metchnikofi', Dr. Jamaleia has vaccinated — In 1886, 324 patients, by simple treat- ment; mortality, 3-39 per cent. In 1887, 34.5 patients, by intensive treatment; mortality, 0*58 per cent. In 1888, 364 ])atients, by the intensive treatment; mortality, 0*64 per cent. During these three years, 1135 patients have been submitted to the anti-hydrophobic treat- ment, with a mortality of 1'41 per cent. In Moscow, at the Anti-hydrophobic Institute, founded imder the patronage of Prince Dolgorovtow, there have been vaccinated — In 1886, 107 patients, by simple treatment; mortality, 8 '40 per cent. In 1887, 280 patients, by intensive treatment; mortality, 1-27 per cent. In 1888, 246 patients, by intensive treatment; mortality, 1'60 per cent. At Varsovia, M. Bujivid inoculated 297 patients by simple treatment, the mortality being three j)er cent.; 370 patients by the intensive method, mortality till now, 7ii/. Already sixteen months have elapsed since the first application of this method, and two months since the treatment of the last patient. 538 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. In Samara, Dr. Parchenski vaccinated fifty-three patients, of whom four were bitten by wolves. The mortality here (very high, 5-67 per cent.), is explained by the fact of the treatment not being sufficiently energetic and kept up, as explained by Dr. Parchenski. At Charchow, probably for the same reasons, but without knowing precisely, Dr. ProtopopofF vaccinated 233 jDatients, with a mortality of 3-80 per cent. In Milan, Dr. Bai-atieri vaccinated 335 patients ; two are dead,^ notwithstanding the treatment. Mortality, 0"60 per cent. In Palermo, Professor A. Celli vaccinated, from the 1st of March to the 30th September, 1888, 109 patients, without one failure. In Naples, Professor Catani, assisted by Drs. Vestea and Zagari, was forced to close his laboratory, not receiving any income from the municipality from January till August, 1888. In that town, Pasteur's numerous adversaries, notwithstanding a vote of confidence and encouragement from the Academy, had succeeded in shaking public opinion, and in disposing the municipality against Pasteur's method. But during this period of seven months, nine deaths by hydrophobia having occurred in Naples, the municipality agreed to give an endowment. The Government and the province of Naples also promised some help, and the laboratory has been opened once more ; it is novv in full working order. Two hundred and forty-six patients have been vaccinated in Naples — 199 since the opening of the laboratory (22nd September, 1886) till January 1888, and thirty-four since its re-opening. Mortality after vaccination being 1*5 per cent. In Havanna, in the Anti-hydrophobic Institute of Dr. Santos Fernandez, Dr. Tamayo inoculated 170 patients, amongst whom fifty had been bitten by animals proved undoubtedly mad. Mortality being 0*60 per cent. In Pio de Janeiro, at the vaccinating station due to His Majesty the Emperor of Brazil, Dr. Ferreira dos Santos vaccinated fifty-three patients. Up to date, there have not been any failures. The foregoing statistics are official. I have the documents in hand. Other statistics I do not admit. After enumerating these results, I do not add any commentary. They furnish the most eloquent answer to the detractors of the Pasteur method, for no one can demolish them. I will conclude by saying, that I hope Australia may be always jirivileged, and continue to be kept free from hydrophobia by the severe measures which do honour to its legislators. But, should there be any ]iydroi)hobia here, I am confident Australia would not allow herself to be surpassed by all the other nations, and that there would be a branch of the Pasteur Institute established here ; and I prophesy of Dr. Wigg that, knowing his love of truth and his professional integrity, he would be amongst the first to vaccinate his own patients. IS CHOLERA QUARANTINE SCIENTIFICALLY SAKCTIONED. 539 IS CHOLERA QUARANTINE SCIENTIFICALLY SANCTIONED 1 By K. R. KiRTiKAu, M.R.C.S. Eng., L.R.C.P. Lond. Surgeon H.M. Bombay Army. Civil Surgeon, Thana. India lias been tlie home of cholera for ages past. India's commercial relations with England, I may even say with Europe, ai-e daily getting stronger and stronger. The wonderful speed with which steam com- munication between the two countries takes place, has rendered the transportation of infectious and contagious diseases from India to Euro])e more frequent. The chances of the introduction of cholera, therefore, from the one country to the other, are daily increasing. India is never free from cholera throughout the year, or at any rate, at some part of the year. In some part of the country or other, there is cholera present, either in an epidemic, or a sporadic form. When we remember the formidable nature of this disease, it is but natural that there should be a strong desire on the part of the authorities who regulate the international communication of the different countries, that the disease should not only be kept at arm's length, but stamped out; that the ships from Indian ports, coming from an infected locality, should not be allowed to be the importers of cholera into the harbours which they touch. Eight days' quarantine, or ten days' quarantine, is sometimes enjoined. This has been considered by some not so much as a hardship, and as an infringement of one's rights, on account of ignorance on the part of the advisers of the respective authorities enjoining the quarantine; nor even so much as a personal grievance, but, what is most ridiculous, a practice not borne out by the most advanced and acce[)ted scientific principles of the day. It will be my jmrpose to show this to you briefly. It must be remembered, that cholera is a protean disease — insidious and sudden — as sudden in coming, as it is in departing. No two epidemics are alike, and each man who observes it clinically, observes it as lie tinds it. Writers have therefore differed most mateiially some- times, and this is the reason why the true etiology of the disease is buried in so much mystery. In India, the cholera question is looked at from two points of view. We have what I woidd call the sceptics, or as Dr. de Chaumont calls them Nihilists, who think, and very rightly too, that the true cause of cholera is unknown. They believe that there is some telluric, climatic, atmospheric, unknown condition, which influences its rise, spread, and subsequent subsidence ; that cholera does not spread by human inter- course, and that even if it were demonstrated that it did so spread, nothing could be done to prevent such intercourse. They further maintain, and .strengthen their position I think, by advancing the fact, and it is a fact borne out by my individual experience of over fifteen years, " that attendants on cholera cases, do not necessarily suffer from cholera, nor ai-e they attacked in larger proi)ortions, or with greater frequency than other classes of peojile, which they would certainly be, had cholera been propagated purely by human intercourse by human 540 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. contagion and infection." Further they say, that " isolation of the sick and disinfection of the discharges, are valueless." — (Cunningham.) There are others who maintain certain pet theories, who ignore the experience of others, and force their own on the world. I class them under the head of alarmists. Chief among these, are those who attach undue importance to one or other particular cause, such as human intercourse. This is rather a comprehensive term. Dr. Duncan, a young Bengal Surgeon of the Indian Medical Service, who has recently been awarded the " Parkes Memorial Medal," for 1886, for his essay on the prevention of disease in tropical and sub-tropical campaigns, and who is a vigorous, I should say an uncompromising, advocate of the human intercourse theory, includes vnider these two words, the following incongruous mass of one thing and another : — " suffice it," he says*, *' to enumerate the air, the drinking water, the cooking water, the solid food, the bedding, the tents, the bodies of the dead ; and dominating all these, the dejecta of the sick or their effluvia." It is forgotten by this class of thinkers, that when cholera breaks out in an epidemic form in a town, several cases occur all at once, having no connection with each other of any kind. Where cholera is endemic, one case may occur or one hundred at a time, without personal contact. Some of these mono- theorists attach so much, and such undue, importance to drinking water alone, that they get completely lost in their solitary idea, and think of no other equally potent, or even under some circumstances a more potent, or perhaps the only mode of infection. Thus, for instance. Dr. JNIadSTamara says: — "That if we only preserve the drinking water from contamination, it is out of the question, cholera should become ej)idemic in either town or country." In saying so. Dr. MacNamara furnishes me with an argument against cholera quarantine. A cholera case, according to him, may remain in the close vicinity of the drinking water reservoir without danger, i.e., he would say : — " Guard the water against the inroads of the affected person, and you need not fear his presence." It has however been my experience, that other causes than contamination of water have brought on cholera, such as tainted food supply. Cholera has prevailed under my eye in Sibi, and in Thana, notwithstanding a pure and uncontaminated water su]:)ply. In June 1879, during the late Afghan Campaign, I was in medical charge of the outpost at Sibi, in Southern Afghanistan. Our water supply was run- ning and abundant, coming down from the Nari gorge clear, sweet, and uncontaminated. There was no cholera in its ripal villages. The river runs north to south. Cholera, on the other liand, had been marching from south to north, in the line of our communication, from Sukkur, Jacobabad, through Kutchi Pat — a barren waterless tract in Balochistan, extending over ten miles. It touched the towns of Haji-ka-shaho and Bugh, killing several men along the southern course of the Piiver Nari, to the north of which we had our outpost (infantry, cavalry, and native followers) flocked together. This ei)idemic of cholera subsequently i-eachod Dadur, and only thence came to us, as we received our rations from th(! Dadur Depot Commissariat. Not long after, it i)assed through the Bolan Pass, and thence it went on to Quella. Thence it travelled on through the Sind Hor.se Cavalry post at Khooshdilkhan, and tln'oiigh ' Op. cit., p. ai2. IS CHOLEKA CiUAHANTINE SCIENTIB'ICALLY SAKCTIONED. 541 the Khojak Pass on to Kandahar, at the speed at which human inter- course can reach from place to place. Now, if we liad held the sole theory of these drinking water alarmists, we should have felt ourselves insecure in our outpost only, on account of our water supply, or rather secure because our river was running north to south, and we might have misspent our energies. But I knew it was no good lending myself to one theory, and I was prej)ared for an outbreak, and as sure as anything it came our way before it had travelled through the Bolan Pass. This stands on the records of the Deputy Surgeon-General of the Sind Division, under whose orders I was then working. We have now to take cognisance of the germ theorists. The germ theory is a mighty question, vast in its extent, difficult of verification, and weighty in its results. It is at present in its infancy; it would be presumptuous to discuss its merits here; it would be premature, and even perilous, to consign it to oblivion. We are living in the age of microbes. Koch, with all the advantages of modern microscoi)ical ajjpliauces, claims that he has demonstrated that cholera is due to a specific bacillus which, under certain favourable eii-cuu)stances, can live and multiply. Those favourable circumstances are principally tlie alkaline state of the human intestines. Koch further says that the acid secretions of the stomach destroy it, that it is present in every cholera stool, and that it is the cause of Cholera- A siatica. Now, Gentlemen, the e^■idence which connects the particulate organism, or the comma bacillus, with the origin or causation of the disease itself, is highly unsatisfactory. It has yet to be proved what the contagium vivum of cholera is, and how it is carried about, whether as a s])ore, or as a bacillus ])ure and simple; for be it remeinbei'ed, according to the latest classification of Professor De Bary, the cholera bacillus, whether it is a bacillus, or a vibrio, or a spirillum, or the repi-esentative of a genus midway between bacillus and spirillum, as Trouessart says it is believed to be, it is one of the endosporous bacteria, i.e., having their spores formed endogenously, whether Koch has been, or will be able to find its spore or not. Klein thinks the poison of cholera is of the nature of a ptomaine. Bellew, an officer of vast Indian experience, calls it an influenza of the raucous membrane of the intestinal canal. Such is the state of our present knowledge — theories beai'ing out certain points, and conflicting on the other hand with certain other equally well noted experiences. Now let me })roceed to examine how our pi-esent stock of knowledge helps us in the consideration of the question of quarantine. Dr. Duncan's work supplies me abundantly with facts which can be used against the present system of quarantine : — (1) Dr. Van Gazel, of Gangam, gives an instance of what occurred in his district. "In 1885," he says, "cholera raged all over the Gangam District, but Gopaulpore suffered immunity. The villages in the neighbourhood of Go])aulpore were all affected, communication from which daily occurred "with Gopaulpore. But the latter village had, absolutely, no tanks whatever." Thus it follows, that if the tanks were stopped from being contaminated, were covered up, closed entirely for washing purposes, there would be no necessity for quarantine. (2) Dr. Duncan says : — " Reviewing all evidence, we see that evidence, involving practically all parts of India, coincides in one direction. The investiga- tion of those in chief sanitary authority bear testimony, as conclusive as 542 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. testimony can be, that cholera-polluted water is the cause of cholera epidemics." Nevertheless, such evidence has been passed over as one- sided, and held to be of no value. (3) Dr. Johnson, of Hong Kong, declared at the Medico-Chirurgical Society, that the disease was frequently introduced there, yet it never became epidemic; and this he showed to be entirely due to the excellent water supplied and obtained from lofty reservoirs on Victoria Park, and used by the inhabitants. He was also in charge of a man-of-war, which entered Shanghai harbour at a time when cholera was raging round him. Some of the crew became infected. Immediately all on board were ordered to drink distilled water. The ship steamed away north, and the epidemic ceased. There were other ships also infected, which likewise went away north ; but as they were using the water they had brought from shoi-e, cholera continued, and only stopped with the stoppage of the tainted water, and use of the distilled water instead. If, as Dr. Duncan says, water is the only medium for conveying poison, as long as the water is protected, there is no scientific reason whatever why harbour quarantine should be enforced, supposing a ship came from an infected locality, had no sick men on boaixl, but was kept out merely Ijecause it is the rule, and it may be that a case of cholera may occur. This leads us to the consideration of the question of incubation. How long can a man be actually with the cholera germ in his system, and yet apparently well. Dr. Pringle fixes it at two days. It is not very easy to determine this. It may be ten days, or even more. (4) The next argument against cholera quarantine is, that it is a noted fact that epidemics do not arise in a town from one imported case, especially if the town is healthy, and the cholera stools are carefully disposed of (burnt), and thus effectually destroyed. (5) Professor Frankland's experiments show that Koch's bacilli grow very quickly in sewage. Thus, where the cholera stools are not brought into contact with sewage, there is no necessity for jn-eventing ship's men from landing if the ship comes from an infected locality, or even if they have a cholera case on board. Frankland's experiments would seem to conflict with Koch's, however, for we know that in sewage there are putrefying organic matters, and Koch has shown that the existence of putrefaction arrests the growth of cholera organisms. Here, then, is need for fui'ther research, as Pro- fessor Koch himself allows. (6) The next argument against cholera quarantine is the idea that " stools are the most important poison bearers, if not the only poison bearers." If, therefore, you destroy the stools, by burning them, you need not insist on quarantine. Koch and Pettenkofer urge that tlae cholera stools are poisonous directly after they are i)assed, whilst Thiersch would hold that a certain change is necessary before they attain their infective power. Corrosive sublimate is considered the l)est and most reliable destructive agent for orerms — a five per cent, solution. I say burn them. (7) I may add that Professor Lebert, of Breslau, does not believe in quarantine' at all. In the face of Koch's theory, that the drying of cholera bacillus in mere open air kills the germ, the process of disinfection is rendered unnecessary, and cholera would seem to be shorn of all its pristine gravity. "The dread of cholera must vanish ; and the necessity of disinfecting, entailing such a large expenditure of money, time, and energy to municipalities and health boards to find disinfectants and IS CHOLERA QUARANTINE SCIENTIFICALLY SANCTIONED. 543 germicides, should, a priori, vanish, especially in such a hot country as India ; but it has been my experience that, in a temperature of 115° in the shade, and 130" in the o)jen, lasting for over six hours — when medicine bottles have gone to pieces, and measure glasses cracked from sheer heat — we could not kill cholera germs straight off (as would be imagined should have happened of a necessity if Koch is right), when cholera bioke out in our outj)ost in the hot plains of Sibi, in the year 1879. If Professor Koch is right, well may Cunningham, Hunter and Fayrer, who represent the sceptical school, exclaim, " Our task is done ! Mere act of drying is enough disinfection ! We don't insist on more !" Dr. Cunningham says the same thing. He says there is abundant evidence to show that isolation of the sick, and disinfection of the discharges, are valueless. Koch however recommends, as an additional measure, boiling of clothes and bedding for an hour, and soaking in a solution of cori'osive sublimate (four ounces to a gallon) for two hours; or immersion for twenty-four hours in a weak solution of carbolic acid (two per cent.) and chloride of lime (one per cent). As long as the true period of incubation is not settled, quarantine by sea cannot be fully established. In a report on the diffusion of cholera and its ))revalence in Europe during the ten years 1865-74, submitted to the Medical Officer of the Privy Council by Mr. Netten Ptadcliffe,* we read as follows: — "The experience of this country since 1865 has tended to show that cholera may be carried greater distances in a latent or undetected form than had previously been suspected. The instances I have already quoted, of bodies of emigrants travelling from infected districts of the Continent across the German Ocean, and across England, several days' sail out into the Atlantic Ocean before any sign of cholera was manifested among them, are peculiarly instructive with regard to the question now under consideration." What then is the use, I ask, from a scientific point of view, of subjecting a ship from an infected port, from India for instance, to mere eight or ten days' meaningless quarantine 1 There is no rational answer. The common mistake that is made in connection with the question of quarantine by sea and by land is, that the term "human intercourse" is understood to mean '•' propagation." The terms are made co-extensive. The one may lead, I admit, to the other ; but is not, nor need be, the sequence of the other. There may be ever so much human inter- course ; but if, as the necessary condition of that intercourse, there is every care taken to destroy or disinfect the discharges from a cholera patient, then I submit, all the necessary precautionary measures so far as we understand them, and so far as we can control them, will have been adopted, and every possible danger averted. The Vienna conference of 1874 unanimously accepted the conclusion of the Constantinople conference of 1866, that "Cholera is transmissible by goods employed for personal use coming from an infected place, and especially by such as have been used by cholera patients ; and that there are even facts which show that the disease may be conveyed to a distance by such goods if they have been kept close and unexposed to free circulation of air." This is what the Vienna conference admits. If it be so, then it stands to reason that there would be transmission of * EeportB of the iledical Officer of Privy Council. New Series, No. 5, p. 146. 544 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. cholera possible by merchandise arriving from an infected locality. The possibility of such an occurrence is even probable. Take, for instance, the case of the Indian wheat and rice, and other articles of food that annually leave the shores of India for the European markets. India is no longer the curiosity shop it was in the olden days of the East India Company. It is no longer the repository of the barbaric pearl and gold. That envied position is now transferi'ed to your colonies. India is now the granary of England, and is daily increasing in importance. To give you an idea in quantity, take the wheat sent out from India in 1873. It was one and three-quarter million cwt. ; it is now sent out to the extent of twenty-one million cwt. Up to 1875, the export of oil seeds have averaged about four million cwt. ; " but," says Sir William Hunter, " they were freed from duty, and by 1885 the quantity exported had grown to eighteen million cwt." Tlie rice trade has not shown such considerable increase, but still we send it out to Euro[)e in large quantities enough to infect all England, or even Europe, if tainted with cholera poison. Now wlien we come to think of the habits of the people who gather the corn and the oil seeds from fields and forests of India, and when we know they are by no means scrupulously clean, or mindful of sanitary laws, if at ail they are made aware of them, I cannot helj) thinking and even feeling a sort of apprehension, that the more our Indian grain bags are exposed for sale in European markets, the greater is the chance of cholera contagion being introduced from the east to the west — from India into Europe. When ships carry such bags from tainted localities, is it not reasonable to expect that they should be subjected to quarantine rules ? But how are the authorities to know where the bags come from — from tainted cholera districts, or otherwise themselves tainted, or not? All this it is impossible to know; the exporting merchants won't know it, and won't tell if they know it; the inland field purchaser, or broker, would hardly be aware of the danger of buying the grain in a cholera-stricken locality ; and what is the result 1 Practically, the grain coming from a cholera-stricken country, is exempt from sanitary rules and quarantine cordons; and the human being — clean washed men and women, coming from cholera-stricken localities — perhaps equally tainted, or maybe, quite untainted, have to go through the rigid observance of quarantine rules ! Is it not all a farce 1 I ask, therefore, are not our present quarantine measures highly unscientific 1 What Sir Ranald Martin said years ago, applies with still greater force to the circumstances of our own day : — " Quarantine can no longer be adopted," he says, "as the means of preventing the entrance of cholera into England, for it is incompatible with the present state of commercial intercourse, and with the well-being of a commercial country." Far ])etter, I say, therefore, would it be to direct our whole and sole energy to the isolation of those who are actually sick, and to the destruction of their excreta, than to waste our time, energy, and money in carrying out what is a mere mockery of (juarantine — a shadow, instead of the substance. Koch has said that cholera has never reached Europe from India by merchandise; "we have," he says, "letters and parcels sent by post; they have never carried cholera." This aftbrds an additional argument against the jjresent quarantine arrangement. Yet it can never FEDERAL INSPECTION OP FOREIGN-GOING SHIPS. 545 be said tliat cholera may not be so transferred. I have handled hundreds of daily cholera re])orts sent to me by village officers and town officers from infected places, where cholera has often fiercely raged, but neither have I, nor my assistants, ever suffered from the disease, and hope never may. Pettenkofer very rightly observes, that a germ of cliolera may remain latent even a whole year, he does not know exactly how long. Mr. John Simon, tlie great sanitary patriarch of England, has said, and said truly, " that Her Majesty's Government has been now for years past promoting the study of cholera in India, with the best lights of contemporary European knowledge, and no one will doubt but that here, as in other departments of medical research, truly scientific study must eventuate in practical good." "If," says this veteran hygienist, " the constantly developing and constantly accelerating commerce between India and the rest of the world is not to carry with it a con- stantly increasing terror of pestilence, the safeguards, I apprehend, will consist, not in contrivances of quarantine to maintain from time to time more or less seclusion of nation from nation, but rather in such pro- gressi\'e sanitary improvements on both sides as will reduce to a minimum on the one side the conditions which originate the infection, and on the other side the conditions which extend it." Quarantine separates, I most emphatically say, man from man in the most unwarrantable manner, in the most cruel manner, and in an utterly useless manner; commerce on the other, unites us, and strengthens the bonds of mutual sympathy. Let us therefore, not only as men of science and culture, but as the contributors to the commerce and the "human intercourse " of the world, never forget the golden words of one of England's greatest ])oets, that : — " The bond of commerce was designed To associate all the branches of mankind, And if a bomidless plenty be the robe, Trade is the golden girdle of the globe ; Wise to promote whatever end He means, God opens fruitful nature's various scenes ; Each climate needs what other climes produce, And offers something for the general use." THE NECESSITY OF FEDERAL INSPECTION OF FOREIGN- GOING SHIPS ARRIVING AT AUSTRALIAN PORTS, COUPLED WITH ISOLATING AND FEDERAL QUAR- ANTINE LAWS. By A. E. Salter, M.B., Thursday Island. It must be understood that I use the term " federal " to indicate that these acts should be done under intercolonial treaty, not that we must have intercolonial federation first. Of all those things which afi'ect the welfare of mankind as a mass, and under the influence of which all varieties of human beings come, irrespective of language, race, religion, or climatic and geographical peculiarities, none is applied so absolutely to all, and none is so important, as the liability to disease and death ; In S46 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. and means for the prevention of the first, and averting the second, are questions of the most vital importance to all the inhabitants of the globe. The great political questions of the day are subjects which have for their ultimate object selfish ends in view ; and nations, when studying any of these questions, ask themselves, which is best for them to advocate from their own jioint of view — which will benefit them the most, and their neighbour the least 1 But in circumscribing and isolating preventible diseases, the benefit of all the individuals of the different races of mankind is held in view ] and if such a thing as unity of action among all states, having for its object the suppression of certain infectious and contagious diseases throughout the world were ever brought about, those diseases would soon cease to be known, except as matters of medical history. Thisend attained, would produce both a great improvement in the huuian race as a race, and mitigate the sorrow and pain of the individuals of that race. But such a thing as unity of thought among all the earth's nations on this subject, or, perhaps I should say, better unity of interest, seems still a long way off. It would be beneficial, however, if unity of system, having for its object the isolation of infectious diseases, could be attained among states which are conterminous, and one step would have thus been made in the direction of the unity of nations for the same purpose. The minds of men are in a state of perpetual excitement concerning things which they believe must benefit themselves, their friends, or their nation ; but there is perhaps nothing about which all their opinions would be agreed so much as that it is good to prevent disease. It is with the hope of helping towards this object in Australia that I bring under notice the necessity for a unity of system among the Australian colonies, by virtue of which virulent, infectious, and contagious diseases may be no longer carried from port to port as has been hitherto the case, but may be removed and treated as early as possible. I shall not indicate any particular places which are more suitable than others for the purposes of isolation, though I shall refer to a few chai'acteristics of these Straits, which well qualify it for such a filtering station. Possibly other places exist which may suit better. We require similarity of quarantine law, in order that gi'eater safety may be given to the inhabitants of Australia, to the healthy passengers in ships, and to those who may be sick on board ship; and so that anomalies, such as have happened under existing multiple systems, may cease to be known. For a very considerable time a system, having as its object the interception and isolation of infectious diseases brought to this country by sea — such system to be maintained by the united Australian colonies — has attracted the attention of the statesmen and sanitary authorities of Austx'alia. Some have objected to our present quarantine, on the ground that it has been tried in Europe and America and found almost useless, and in the case of Great Britain, abandoned ; but, even these will, I think agree, that the inspection of vessels ai'riving at the first port of call on the Australian coast, and the removal of any cases of infectious diseases, is a necessity. As to the question of quarantine in Europe, it has been a much debated one, and the sanitary authorities of England have come to the conclusion that sufliicient benefit did not result from it to comjiensate for FEDERAL INSPECTION OF FOREIGN-GOING SHIPS. 547 the injury to trade caused by it. Accordingly, England has only a system of inspection, and removal of contagious and infectious cases at the port of call. Now, the comparison between (^reat Britain and Australia is not a good one, because, as has been ])ointed out, Great Britain has a most excellent internal sanitation, and Australia has just as bad a one. This is a difference between the two countries which time ought to overcome; but there are differences which appear to me of more importance, since they cannot be got rid of — they are geographical and meteorological. The Australian colonies are isolated from other countries much more comjiletely than Great Britain is. The continent of Australia has an innnense coast line, at various points of which vessels arrive, and thence travel along her shores for days, and thousands of miles. In Great Britain such journeys are impossible, and did they take place even under the English system of inspection, it is certain tliat vessels would not arrive at ))orts having cases of small-pox, scarlet fever, or cholera on board, and lie compelled to go out of them with their cases still on board. Yet this is precisely what happens in Australia. England's internal sanitary arrangements are unsurpassed; but even they are being continually improved, and the authorities expect to get great benefits from the Local Government Act just passed, while everywhere isolating hospitals for special diseases of an infectious nature are being built. As to Australia's internal sanitary arrange- ments, it is correct to say that no scheme carried out under Intercolonial Treaty exists ; from which it follows that, while one colony may be expending large sums on its own internal sanitation, its neighbour may be doing nothing at all. It is to be hoped that a commencement in the direction of unity in this very important matter may be made by the establishment of federal medical inspection, and isolating stations. As to meteorological differences between England and Australia, the temperature of the former is very much lower than that of the latter. The winter of Great Britain is almost sufficient, itself to inhibit the vitality of the infecting particles where they become exposed to its influence outside the houses. And last, and most important of all, Australia has no united plan for the isolation of those cases of disease arriving by sea which, as I have pointed out, Engldnd has, and which 1 am now advocating for Australia. Having in view these great differences between the two countries, I take it that the result obtained by a comparison between them is not sufficiently valuable to be entertained. At any x-ate, it seems to me that for those who will persist in arguing from this comjiarison, the only conclusion is, that if it is a bad thing to have quai-antine because England has not got it, that is, if it is a bad thing to differ in this law from her, it is a good thing to resemble her ; and therefore, those persons will be in favour of isolating stations which — as Australia is not like Great Britain, one empire, but several colonies — must be maintained under Intercolonial Treaty ; that is, a federal inspection and isolating system, and federal quarantine laws, under which the infecting cases would bt^ removed before the vessels carrying them reached the centres of population. During the last eighteen months, it has quite frequently happened that vessels have passed through Torres Straits, having one or more cases of small pox on board, and thus freighted have proceeded past In 2 548 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Cape York, southwards along tlie eastern coast for nearly two tlionsand miles, reacliing Sydney at last, wliei-e the infectious cases have been removed, if they have not already died before reacliing that port. That is, we have a vessel passing within a mile of a port where, if the patients could have been landed, they could have received that attention whicli can be given with so nmch greater advantage ashore, while the passengers remaining in the ship proceeding on its voyage, after being cleansed and disinfected, would have travelled more safely, and the shipowners would, in the event of no more illness breaking out, have been saved the expense of a number of days in quarantine; and superadded to these advantages, such highly infectious and contagious diseases as were on board would have been kept away from the centres of population, and possibly, such a contingency as the infecting of families outside the quarantine station at Sydney have been avoided, the disease being left at the least thickly populated part of Australia, instead of the most thickly populated. Under federal quarantine or federal inspection, another advantage and a very material one would be gained, in addition to the sweeping away of the present inhuman and barbaric state of things ; the advantage to which I refer, is the co-operation of the charterers of steamships, in the detection of suspicious cases. These latter deserve the greatest credit as a class, for the way in which they have always assisted the Health Department in the detection of cases of di.sease. Still, it is not part of their business to co-operate witli that department, much less is it to their advantage under the present Laws; but under the new regime, which I trust some day to find adopted, and which I wish to indicate in this ])aper, they would have every inducement to assist in the detection and expulsion of such cases. It would be so clearly to their advantage, and to the conducement of their comfort, that they would only too willingly seek to discover any disease. Where now a master of a shi]>, if he were unscrupulous enough, might misstate the number of his passengers and crew, on account of his intention to conceal one of them, who appeared sickening ; iinder the more favoui-able circumstances, he would be only too glad to indicate the case and get rid of it, seeing as he must, how advantageous it would lie for his owners and passengei's, not to have a source of infection, which hourly was threatening to spread itself in spite of all his precautions. Again, the necessity for isolating stations at convenient ports, is as great as the necessity for infectious disease hospitals ashore, such as are now found to work so well in Great Britain. This is a greater necessity ; for it is possible, that sick persons ashore may get the best attention, but a person on board ship, affected with a deadly contagious or infectious disease, must expect to be looked u])on with dread by all on board ; and we must all know that the facilities, even on the best appointed steamship, can be but indifferent, compared with those which lie may reasonably expect ashore. Humanity alone urges the establish- ment, without further delay, of such isolating stations, which may be called the disease filters of Australia. Many people ai-e, perhaps, unaware of the course usually pursued when a person on board ship is found to be suffering from a disease which the master has reason to believe may prove to be an infectious one. To such, it may be news to learn that the sick ai'e placed in one of FEDERAL INSPECTION OP FOREIGN-GOING SHIPS. 549 the ship's boats, over which a tarpaulin is erected to protect the invalid from the sun, wind, and rain. This portion of the ship's furniture being tlie most isolated and easiest disinfected, and the least expensive to destroy, is the place chosen for the future home of the pest stricken patient, until he is put ashore. I do not think it is necessary to enlarge upon the condition of the poor mortal condemned to pass eight to ten days of his existence under such circumstances, at a time too when he wants all the help he can get from his fellow-beings, and all the skill likewise. As the greater number of vessels passing this port do not carry medical men, the unfortunate sick have not much to depend upon in this respect. No doubt the boat is the best place at the captain's disposal; he does his best for the man who is infected, and also for those not infected, by placing him there, but for the person to remain under such circumstances after he has passed close to a port, should be quite beyond a civilized nation's ideas of humanity. The facts of the case, I feel sure, only require to be generally known to the Australian people for them to terminate so bad a condition of things. One more proof of the necessity, by analogy. It is admitted that it is good that ships should be inspected, and their diseased passengers isolated, at Port Phillip Heads, at Sydney Heads, at Moreton Bay, and not at Melbourne city, nor Sydney city, nor Brisbane city. Is it not then still better that the ship should be inspected and its cases isolated at some port further removed in the line of call, such as Torres Straits. I now come to those particulars in connection with Torres Straits, which specially fit it to be an inspecting and isolating station. It is to the East Australian Coast, what Port Phillip Heads and Sydney Heads are to their respective cities, for very few vessels indeed do, and still fewer will, in future, pass outside these straits when coming to East Australian ports. Whenever they do so come outside, they must pass to the north of New Guinea. The course over ninety per cent, at least adopt is to come along from Java to Torres Sti-aits, and through the channel between Goode Island and North West Reef — through the passage known as Prince of Wales Channel — on to the passage between Albany Island and the mainland, and south to Cooktown, Sydney, Melbourne, and Adelaide. One other point has Torres Straits in common with the Heads before referred to, it is the pilot station for the channel through which the vessels pass down the coast; it is there the pilots are taken on board, although the port may not be entered — a matter which is only of importance in so much as it goes to prove that no more hardship would be entailed upon a vessel in compelling it to be examined at Torres Straits, than is entailed by compelling it to be examined at Sydney Heads, and the result, as I have tried to explain, would be much more to its owner's advantage. At present, it is as if it were decided better that ships should be examined at Port Melboui-ne and the Circular Quay, instead of before reaching those populated localities. If, however, it is better to isolate your infectious diseases at the boundaries of the chief ports that is at their entrances, it is better still to isolate at those entrances still more remote to the continent itself. It has been argued by some, that it is no use establishing such stations and having such insjtectionK, because the disease may not be developed at the time of the ship's arrival at the inspecting port. Now, 550 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. that the disease may be undeveloped, is perfectly true, but it is not in itself any reason why the stations should not be formed, for if it were, it would be a reason why stations should not exist at Port Phillip Heads or Sydney Heads, or the entrance to any other port. Those stations are there to detect and stop disease, if it be found present, and they can do no more; if they do it once in twelve months, they prove their usefulness. As a matter of experience, too, these diseases have generally happened before arrival, even at Port Darwin, and during the last epidemic of sniall-pox in China, ship after ship passed this port with cases of small-pox on board. In my opinion, these intercolonial isolating stations should be a commencement, in part, of a system of sanitation of the whole of Australia. And, at all events, from every point of view, a place should have been in readiness for the cases which have occurred in the past, and most assuredly will occur again in the future. It is, after all, an outer line of defence. It may be carried, but it shoiild be there; and as a nation should be prepared to defend itself against warlike neighbours, so should it be prepared to intercept infectious disease at its different gates. As the entrance to its harbour should be guarded by torpedo mines, so should that entrance be made to act as a filter to waylay infectious diseases, and prevent their further march. Is it necessary to say more 1 The matter seems to me to be one of those facts which commend themselves to the common sense of all, and only requires to be known in order to be accepted. As to the need of a uniform quarantine law, I think the citation of a few examples of what actually has taken place under our existing multiple system of quarantine law is sufficient to prove the urgent need of a change. During the small-pox outbreak in Tasmania some of the colonies enforced quarantine against Tasmania, others only treated the vessels to inspection, and others did not do that. There was no good reason why they should not have followed one uniform system; and it made the law appear ridiculous when they did not. Suppose, for instance, that Victoria rendered twenty-one days quarantine imperative against ships fi'om Tasmania, but New South Wales deemed inspection alone sufficient, what would result 1 Why, Victorian passengers would proceed per steamer from Tasmania to New South Wales, and thence per steamer or railway to Victoria, the time taken up only being a few days longer than by the old direct way of travelling, and the risk of persons coming into Victoria liable to the disease being just as great. With the law uniform, this could not occur. What one colony enforced, the other would enforce. One more example of anomaly, resulting from difference in quarantine law. Early in this year the law of Queensland said, " No ])erson shall land at a Queensland port who has had communication with a Java port, unless he do fourteen days quarantine." The quarantine law of New South Wales said, "Java is a clean country, we do not intend to quarantine any person arriving therefrom." What then happens? Passengers in Batavia wishing to come to Queensland, take ship for Sydney, and arriving there take the railway to Brisbane, having been delayed by a day or two, no more, so far as travelling time is concerned, but having l)een put to much extra expense, and perhaps, kept in Java a week or more waitinsr for a steamer. THE EVILS OF SPECIALISM. 551 It is no wonder that people, under those circumstances, hxugh at the eccentricities of the law, and at the same time complain of the expense it puts them to, without achieving the result intended. I might cite other examples similar to these, but it cannot be necessary. Were there unity of quarantine law, these things would be known no more, and much just, but very unfavourable, criticism avoided. In conclusion, it is my earnest desire to see unity of purpose among the Austi'alian colonies, in producing unity of quarantine law, working in combination with a system of intercolonial inspecting and isolating stations, culminating in the production of a system to which other nations may point as an example of good law and of humanity. THE EVILS OF SPECIALISM. By DuxcAN Turner, L.R.C.P. Lond., L.R.C.S. Ed. That specialism must exist in medicine and surgery at the present day, no one will deny. Kept within reasonable bounds, it has its uses; but if allowed to go on multiplying, and so to speak, run riot, it is fraught with numerous and dangerous evils. In my humble judgment it is a cankering sore, which will gradually drain and irretrievably injure the dignity, position, and usefulness of the profession at large. It is not the intention of this paper to point out how to keep specialism in its jilace. My attempt is simply to call the attention of the profession to its mischief, in the hope that some general professional opinion on the subject may be brought to bear to curb it, and restrict it within proper lines. That specialism has great attractions and temptations is true. Indeed, the bed of the specialist is generally so rosy that it is no wonder so many are led into the ranks. For the hard-worked practitioner to emerge from the toils and hardships of general practice to the ease and elegance of specialism, is like escaping from a wilderness of thistles into a Garden of Eden. Moreover, special ])ractice is easy — it is money- making; and socially, the specialist stands as high, if not higher, with the general public as the all-round practitioner. But when the profession is divided and sub-divided into a multitude of sections, that our status must ultimately be lowered, is certain. Quackery will creep in, and it is doubtful whether any legislation we are likely to get in modern democratic days will in any degree check it. Already, we have numbers of people calling themselves eye and ear doctors, who have no education whatever. Why is this? Simply because the laity know there is " money in it," while the public outside are ready to run after a specialist, whether he is educated or not. Not least among the evils of specialism is, that it takes away a great many fees from the hard- worked general ])ractitioner, and that too, in cases he could manage as well, or perhaps better, than the specialist. I am not going to run down specialism in r/loho. Some of its forms uo one oVjjects to. Diseases of the eye have for many years been regarded as a proper sphere for specialism, and it must be acknowledged 552 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. that the best discoveries in the treatment of eye diseases have been made by special practitioners. The same may be said of diseases of other special organs. But none of the great discoveries in medicine or surgery can be claimed for specialists. The mischief is, that the mind of the specialist gets contracted, like that of other special workmen. After all, he is only a superior workman. I have heard of workmen in Birming- ham who make nothing but hinges all their lives, and no doubt, they attach a vast importance to their calling, and occasionally wonder what the world would do without them. I have no means of knowing their mental calibre ; but I make a shrewd guess that their thoughts are pretty well confined to the qualities of the iron they use, and t)ie pay they are to get. Machinery has in many instances replaced such work- men, and as machinery has ah^eady been made to do elaborate work in the way of calculation, possibly some machine will be invented to do the work of some specialists, just as well, if not better. The human body cannot be split up for medical treatment into fifty or sixty different pieces, and any practitioner who gives exclusive attention to one organ, to the neglect of the others, is sure to blunder, and is, as a rule, unsafe. No doubt there is something to be said in respect of some of the external parts of the body. It has been already admitted that there is no objection to a moderate amount of specialism on such organs of sense as the eye and ear. But when specialism seizes on the internal organs, and one man takes the heart, another the liver, a third the kidneys, and so on, what are we to expect? At present we have no representative specialists for all these organs, but we have them for most, and there are signs that others ai-e coming. Is it not time for us to raise our voices against such abuses, which are calculated to undermine, and ultimately seriously injure, what a dis- tinguished Victorian statesman called the noblest of all the professions. The world has recently beheld a spectacle which, I am afraid, will for a long time be remembered with shame — a set of specialists wrangling over the afflicted body of a distinguished Imperial patient. Who will deny that the whole thing will undoubtedly lower the entire profession in the eyes of the world 1 Among the drawbacks of specialism is hair-splitting, that is, the invention of fanciful diseases and the consequent multiplication of indefinite medical terms, much to the confusion of the young student, and also of the ordinary practitioner. I remember in my student days poring over a large volume well known to you — I mean Erasmus Wilson on skin diseases — and I have a keen recollection that, after several days of fighting with it, I put it down in disgust, coming to the philosophical conclusion — one worthy of Lord Dundreary — that skin diseases were among the things that " no fellah could understand." Now that our knowledge in this direction is extended, and I have had other means of studying these common ailments, I have no doubt whatever that Wilson split up eczema into at least four diseases that liave no justification for a separate existence. Did time ])ermit, I could mention many other diseases dealt with by specialists in the same way. Each specialist is discontented with the name adopted by a brother specialist, and must invent one of his own. Now, 1 ask you, can any tiling be more tantalizing to the student or to the practitioner (for we are students all our lives), than this wading THE EVILS OF SPECIALISM. 553 through a needless multiplicity of names 1 Especially is it confusing and harassing to the hard-worked general i)ractitioner, who is supposed to be equally Avell up in all the diseases that flesh is heir to. In France, the Academy of Medicine put some check on this process ; bub in Great Britain nothing of the sort has ever been attempted, if we except the effort made in that direction by the London College of Physicians. But I feel sure tlie day will come, when there will be a representative intercolonial medical congress to agree upon certain names for certain diseases, and so avoid this terrible and endless confusion. In Melbourne, gynaecology is tlie only specialism that has attained that prominence, when it is viewed with some disfavour by the pro- fession at large. I regret to say that I think there is some reason for this. I am not going to utter a word against the gynsecological practitioners of this city. Many of them are known to be honourable men, and zealous in their calling. But, as I hinted in a former part of this paper, it is one of the characteristics of the human mind, when it dwells on one subject for a length of time, that the understanding gets wai'ped, and it sees things through a coloured atmosphere, which is always more or less harmful to the judgment. The specialism of gynaecology is eminently a money-making one ; no wonder, therefore, that it is such a favourite with the medical profession. At the same time, it is certainly one in legard to which there is great danger of abuse of the trust the jjublic put in us, so that its professors should be specially on their guard not to lay themselves open to the adverse criticisu) of their professional brethren. Our specialists must take warning that, however great favourites they may be with the public for the time being, or however large their yearly income, they cannot for any length of time brave the opinions of their medical brethren ; and there are several instances in recent medical history, where a continuance in such courses brought ruin on those that persisted in them. But it is when we come to gyniecology that we find this delightful multiplication of terms run riot. For example, for that common disease chronic metritis, I find in different text-books at least eight names ; and some of the other diseases of the female generative organs fare as badly. We all know how much faith a woman puts in her medical adviser. We likewise know how many of the ailments supi)osed to be connected with the generative organs of women are pui-ely imaginary, or at most, quite harmless. How easy it is then for an unscrupulous practitioner to fill his pockets full of gold from his nervous female patients 'I Turning to our own sex, we know what rich harvests quacks make from the unsuspecting, who are under a delusion about some purely imaginary disease of sexual functions. If ours, which is generally called the stronger sex, is liable to delusion in this way, need we wonder at what occasionally happens to the weaker one 1 An immortal poet, and a keen observer of human nature, has said — " Then gently scan your brother man, Still gentler, sister woman." The changing fashions that prevail in the treatment of female diseases are, I think, only equalled in their dresses. I am old enough to remember when metrotomy was the panacea for all female ailments. Being over a quarter of a century ia the profession, I have a vivid recollection of how these fashions burst upon us with a flourish of 554 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. trumpets, only to die away after a year or two, if not to be entirely forgotten, at least to take a back seat. Some thirty years ago, metrotomy was accepted as a panacea for almost all tliat female flesh is heir to. Then came Dr. Henry Bennet, with his inflammations, ulceration.?, and caustics. A few years afterwards, the late Dr. Tyler Smith brought uterine cervical catarrh so prominently before the profession that he had a great many followers; and for some years, among London practitioners at least, no woman could have an ache in her head or foot but it was ascribed to this cause. Then came Dr. Graily Hewit, with his versions and flexions, and how many pessaries were invented by different specialists for their alleviation or cure, I would be afraid to say. But it has been reserved for an American gynaecologist to make the discovery in female operative surgery which is so much in vogue at the present day, and judging from the frequency of its performance, has, in this respect, eclipsed all others. I need hardly say that I refer to the well-known operation of Emmet. In this city especially, this distinguished specialist has found many zealous disciples; but, I think, were he present at this Congress, he would be ready to adopt for his motto — "Save me from my friends!" That his operation has been abused, I believe it is the opinion of nine- tenths of the profession in this country; and, what was at first a useful and scientific proceeding, and eminently necessary in many cases, is now got to be received with so much disfavour and suspicion, that the very name stinks in our nostrils, and few men who value their reputation would care to perform it. I hope the day will come when this operation will be relegated to its proper and legitimate place, and no longer practised in the wholesale manner we have been accustomed to witness for some years past. HYGIENIC CONDITIONS OF ABO, FINLAND. By Axel R. Spoof, M.D. The town of Abo, the number of whose inhabitants at the commence- ment of 188S amounted to 27,592, does not yet enjoy a water supply, though one has been in preparation for five or six years. Nor has the town a public .sewer canal system, though to this end a project was wrought out some years ago, and a report was made to the representative of the town. The said project proposed that the cleaning take place by means of sewers and surface irrigation; but this system, in view of our long winters — about six months — during which vegetation is quite dead, was considered to be inapplicable, and hence the project has not been accomplished. In lieu thereof, the authorities have agreed that, in the most populated parts of the town, the fluid excreta be conducted into the river, which runs through the town, and falls into the sea within the port district. The solid excreta is collected in pails impervious to water, and is brought outside the town by means of light carriages, for the most part by neighbouring farmers, who make use of it as soon as possible. The morbility and mortality in some of the most important epidemic and chronic diseases are shown in the table following, which I have HYGIENIC CONDITIONS OF ABO, FINLAND. 555 compiled according to official reports by the Local Board of Health, whose work began in 1880. In order to as far as possible j)revent the propagation of infection, each case of epidemic disease is immediately reported to the town doctor — at present K. K. Kynberg — with indications of the dwelling of the sick. Besides this, the Local Board of Health once a week collects a report from each of the practising medical men, about the number of cases treated by him in the pi*evious week. Blank forms are supplied by the board for the purpose. For statistical purposes, such means are further taken, that every death is to be attested by the doctor who has treated the case, or by the town doctor. The Morhility at Abo 1880-87. Disease. ISSO 477 1881 1882 1883 1884 1885 21 1886 19 1887 Typhus abdomin. . . 31 189 37 56 23 Febris remittens 1_ Febris intermittens j" 774/ 39 254 131 77 57 95 90 578 517 809 724 518 881 822 Mening. cerebro-spin. epideiu. . . , , 4 ^ ^ Dys-enteria 16 ii ii 2 2 12 26 Variola & variolois . . 5 95 17 2 Scarlatina . . 26 5 231 117 98 116 106 15 llorbilli . . 555 46 13 1 4 811 72 3 Rubeola 5 158 14 Eiysipelas idiop. . . 37 48 44 27 13 19 74 86 Febris puerperalis . . 6 13 6 1 3 5 4 3 Diphtheria faucium 82 54 44 62 ) 9 8 f 36 24 Laryngitis crouposa 14 13 14 9i \ 15 36 Pertussis . . 18 98 40 7 239 41 13 4 Pneumonia, croup et pleuritis 353 303 205 237 209 196 185 147 Rheumatismus 149 169 179 121 150 153 94 95 The Mortality at Abo, 1880-81 DiSKASE. Typhus abdomin. . . Dys-enteria Variola Scarlatina . . Morbilli Erysipelas idiop. . . Febris puerperalis . . Diphtheria faucium Laryngitis crouposa Pertussis . . Pneumonia, croup et pleuritis Phthisis pulmonum Diseases of the brain and nerves The number of the inhabitants was 1880 (?) (?) (?) (?) (?) (?) 22,529 1881 18 2 39 3 3 1 9 56 130 37 6 62 3 2 3 3 4 3 26 89 64 1 55 .. 24,916 12 3 19 2 1 7 2 3 34 70 27 25,480 1S84 11 1885 18 58 2 3 31 86 37 81 55 54 25,052 25,796 9 2 19 3 2 6 9 70 113 81 26,365 1887 2 "1 *8 23 42 125 80 27,186 556 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Amongst the means which aim at the prevention of disease, or at least, at the mitigation of its influence, especially with regard to the working class, may be mentioned : — (a) The town supports an infirmary for epidemic diseases, which at present, ought to be organised anew; and in connection with it an oven for disinfection, and a lodging for people whose dwelling and clothes, &c., are to be disinfected; and besides this, a town doctor, two district doctors, two midwives, and four district nurses are paid by the town. The oven for disinfection on Merke's system (Germany), is kept at the free disposal of all, for disinfection in cases of epidemic diseases, as well as for cleaning from vermin objects belonging to any one of the town establishments. The oven is also at the disposal of others, on payment of eight shillings per oven, and four pence per bag. The things are brought to the oven in sj)ecial carriages, and are received at one end of the building, and, if small, collected in bags and placed in the oven, which is then closed. Into it is let a continual stream of steam, of four atmospheres pressure, mixed with hot air. The temperature within the bags rises to somewhat above 100° C. Disinfection having gone on for an hour, the oven is allowed to get cool; the objects are taken out at the opposite end of the oven, and are brought to their owners in hired carriages. Families dwelling in small rooms, and in whom some epidemic disease has broken out, are taken into the disinfecting lodging house, where they will be undressed and bathed, and afterwards dressed in the clothes of the establishment; whilst their own clothing and utensils are disin- fected in the oven, and their dwelling is disinfected by the sanitary police for half-an-hour, by means of sulphur spray (1-1000) mixed with tartaric acid (5-1000), and again made safe by soda spray (1-100). In order to provide, in case of necessity, the citizens, especially those without means, with nursing attendance, there are four district nurses. For the attendance which the nurse has rendered to a patient, she may neither demand nor receive remuneration of any kind whatever. From Wealthy patients the Board of Health collects a moderate tax, which goes to an assistance fund for nurses that have grown old or infirm in the service. The instruction of the nurses is arranged agreeably to tlie princi[)les laid down in Miss Florence Nightingale's " Notes on Nursing." (b) Private associations, limited companies, or employers, have procured sound dwellings in different parts of the town, which afford to the industrious and regular workman a chance, at a moderate rent, to get light, clean, and comfortable houses; of which he may, if he likes, become the owner, by paying during the course of eighteen years, annually, a somewhat higher rent. Such dwellings are built on the Muhlliouse system, and at the end of 1887 there were four terraces, consisting in all of nineteen wooden liouses, each containing three apartments and a kitchen, with a bake-oven. Of such a workman's domicile I send you a ground plan, with intersection and situation, together with a copy of the statutes for the Abo Workman Domicile Company, Limited. In order to countej-act the great mortality amongst tender children, which arises from unhealthy dwellings and careless treatment, there was oiganised two years ago, an Abo Child Protecting Association, after the HYGIENIC CONDITIONS OF ABO, B'INLAND. 557 Berlin manner, witii the object of taking cai-e of tender cliildren up to the age of three years. These are left in charge of nurses, carefully- selected and controlled. The parents also, must contribute monthly sums, larger or smallei-, towards the payment of the mu'ses, but always through the Association. A copy of the statutes is also forwarded. Associations for mutual assistance in case of sickness or death are organised at the following larger industrial establishments, viz. : — Wm. Crichton and Company's Shipbuilding and Steam Engine Works, The Abo Iron Manufacturing Company, The Aura Sugar Refining Com- pany, and the P. C. Rettig and Company Tobacco Works. The balance of tliose four associations amounted last December 1887, to 45,931 marks 25 pennies Finnish money, about £1700 English. Besides this, there exists a common Abo Workmen's Sick and Burial Fund, founded in the year 1879, whose members at present number 529, and the surplus 26,000 Finnish marks, somewhat above £1000. By paying to this fund an entrance fee and a monthly contribution, a workman will guarantee himself or his family fixed subsidies, in case of disease or death. Statistics. Members. Sick Subsidies Paid Funeral Subsidies (Marks a, as in chickens. Hence it was not excreted ; and tliere was no reason why other individuals should become attacked, and practically, others were not, when tlie animals were not domesticated. Possil)ly some little personal feeling had crept into the question, l)ut the Commission simply wanted the truth. Upon the Quesdoti of the Attitude of the State toioards Q'uacks and Quackery. Dr. ^iuLLEN (Victoria) upheld the Medical Practitioners' Act, 1865, as equitable, though imperfect in details. He considered it impossil>le to proliibit quackery, and to be unjust for the State to do more for (|ualified medical men than register them, restrict to them certain recognised titles, and legal status. He considered the action of the ( Jhief Secretary of Victoria, in not allowing the police to prosecute unqualified practitioners, as perfectly legal. Dr. Creed (Sydney), as Cliairman of the recent Commission which liad exposed the extent of quackery in New South Wales, spoke from a full knowledge of the subject. He agreed that proliibition was impossil)le, but maintained that the spurious should be labelled spurious; that for State requirements only the genuine should be selected, and that the public should be put in a position to discriminate the true from the false. Dr. MoRGAX (Newcastle) pointed out how badly they were in need of reform in New South Wales, where the quacks were a powerful body, and did infinite harm to the public. Further, they were recognised by the State; for unfjualitied men acted as Coroners and Justices of the Peace, give medicrd evidence, signed certificates of death, and held hospital appointments. Dr. Springtiiorpe (Victoria) pointed out that the defects in the Victorian Act were — the mode of election of the Board, the absence of power to erase names, the scanty requirements for registration, and the absence of explicit powers of prosecution. The complaint against the Chief Secretary was, that he had actually forbidden the police to act upon information received, though they had so acted for many years. At present no one would prosecute, and quacks were flocking over fi'om New South Wales. Dr. Taylor (Queensland) urged the necessity of reform as a matter of vital importance. Upon the Qtiestioii of the /Sanitary Comlition of the Different Colonies. Dr. Taylor (Queensland) regretted that, owing to unavoidable circum- stances, Queensland was not represented in the list of colonies which had reported tlieir sanitary status. Dr. WiiiTTELL (South Australia), tliough not advocating centralisation in all tilings, considered that the great want in sanitary matters was a powerful central authority. He had thought it a mistake when, last year. Local Boards of Health had been established, and the powers of the Central Board curtailed. After a year's experience, he was more convinced than ever that such establishment was a mistake. 568 INTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Di\ A. Shields (Victoria) said that the Central Board of Health for Victoria was the most abused body in the colony, and had a very hard uphill light to wage — so that such testimony was reassuring. Dr. Appleyard (Tasmania) pointed out that Tasmania enjoyed a fair Registration Act, and a stringent Vaccination Act. Dr. Bonnefin (Victoria) considered the state of Melbourne more than scandalous. He looked for reform, mainly in the education of the public, and considered that medical men should woi'k towards this object more than they did. Dr. Leger Erson (New Zealand) considered the present sanitary executive in New Zealand, as worse than useless. Dr. Morgan (Newcastle) deplored the sanitary condition of New South "Wales. It was simply, that the public and the local authorities were entirely ignorant of what should be done. The profession owed it to itself, to band together and make its influence felt, in the direction of speedy reform. Dr. Springthorpe (Victoria) trusted that the Section would not separate without taking some practical step towards showing the Governments of the different colonies the opinion held by it, upon the sanitary condition of the colonies. It was thereupon decided that the President (Dr. MacLaurin) and the Secretary, Dr. Springthorpe, should draft a series of resolutions for tlie consideration of the Section. The following resolutions were accordingly drafted, and unanimously agreed to: — (1) "That this Section of the Intercolonial Medical Congress, 1889, urges upon the notice of the different Governments of Aus- tralasia the necessity which exists for fresh legislative enactments in all the colonies, with a view to obviate the grave dangers to public health which everywhere prevail, and which, in many cases, are due to easily removable causes." (2) "That, in the interests of the public, this Section of the Congress urges upon the various Governments of Australasia the necessity for amendments in the laws relating to the position of medical practitioners, in oi'der that the public may be in n position, at all times, to protect themselves against the imposi- tions of unqualified persons." (3) " That copies of these resolutions be forwarded by the Secretary to the Federal Council, and also to the Governments of the different colonies." It was then decided that Dr. Springthorpe should bring these resolu- tions under tlie notice of the general meeting of the Congress, so tlmt, if possible, they should receive the sanction of the whole Congress. The Section then adjourned. SECTION OF ANATOMY AND PHYSIOLOGY. PKESIDENT'S ADDRESS. By T. P, Anderson Stuart, M.D. Professor of Anatomy and Phyaiology, and Dean of the Faculty of Medicine in the University of Sydney. In an address on Anatomy and Physiology, one may either speak of the subject matter, as one would before a number of specialists in these branches of learning, or one may treat them in a more general manner as one would before a purely lay audience ; speaking, for instance, of their value as a discipline, or means of education, or of their value in relation to the art of healing. Further, one may deal with them his- torically as they were in the past, descriptively as they are at present, or prophetically, one may form anticipations of their future. I think I shall be most in harmony with the nature of this meeting, if T take up more or less of all these lines. On the Scientific Culture. Before an audience of scientific men I do not need to advocate the training of the mind in science and scientific methods, as a means of education and culture. That the scientific mode of thought and habit of mind fosters the love of truth for its own sake, and constitutes a thoroughly effective mental discipline, no member of this Congress will doubt. That there is, in the cultivation of science, something which imparts a culture in as true a sense as does the study of letters, I do not need to ui-ge here. That the recognition of a scientific culture as such is spreading among men, anyone who notes the signs of the times can perceive. But this tardy and partial recognition has come only after being fought for and struggled for, and the struggle is not yet over. Thus it has all too often happened, that the scientific man has had to waste in contention, time and energy which he would fain have given to his proper work. It should be added that the struggle is not peculiar to Australia — it comes from the older lands. In a sense, therefore, the legend of the University of Sydney is only too true — " Siclere mens eadem mutator The attitude of the ancient Universities of Oxford and Cambridge is worthy of notice in this connection, for in these homes of culture, 570 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA, medical schools have been revived withiii the last few years. In some departments, Cambridge is already worthy of the designation of the " great " school of medical science, and Oxford is making steady progress ; and it is of interest to us in this place to note that both these schools of medicine date their real revival from the establishment of schools of physiology. Perhaps, in some measure connected with this academic recognition of medical science, there has, in recent years, I am told, been a distinct improvement in the manners and habits of medical students. Bob Sawyer is now as dead as Julius Csesar. And yet, let the tree be judged by its fruit; for when we think of the con- fidential relations which must of necessity exist between medical adviser and patient, when we remember the varied and oft-repeated temptations that beset the medical man in his practice, and when we think how seldom he has been found wanting, surely that medical and scientific education cannot have been a bad thing, when it could make such men out of such students. The Physician must be a Physicist. The progress of Physiology during its period of marked progress — say the last quarter of a ceutury^ — shows very clearly that the energies at work within the body are in no wise different from the energies at work in the world without it. The sole difference is in the stage on which they play their parts. Time was, and not so very long ago, when a " vital " force was believed in as it now no longer is, and the phenomena of life were thought to be approachable only on lines some- what different from those on which we would take up the phenomena of the world around us. But now, the whole tendency of the time is to show that vital manifestations are phenomena to be studied as other phenomena are ; and more and more is it clear, that the methods and laws of Physics are to be applied in Physiology. The physiologist is but a student of ])hysics in so far as concerns organised things, to the I'ight understanding of which he must add also a knowledge of their structure. And — like the exj^erimental physiologist — the physician, too, is constantly called upon in diagnosis and in treatment to make experiments, to record observations, and to work out problems more or less j)hysical — in optics, in acoustics, in hydraulics, in mechanics, in electricity, and so on. For instance, the physician now employs electricity to obtain heat and light, to coagulate blood, to modify the nutiition of the tissues, as in the restoration of wasted nerve and muscle, and the dissolution of tumours, &c. The physician even uses the galvanometer, and prescribes doses of electricity in milliamperes, as he would prescribe degrees of teuiperature, or weights of drugs. president's address — SECTION OF ANATOMY AND PHYSIOLOGY. 571 But it may be urged that the physicist must needs be so good a mathematician, that a fair knowledge of physics is beyond the average mathematical attainments of the average student of medicine. This, however, is not the case — some mathematics he must know, but not so much as is often assumed; for indeed tliere are not wanting examples of men of high attainments in physics who were of but moderate mathe- matical attainments. I mention this, because I desire to urge the study of pliysics as a vecessary part of the training of the medical man, and accordingly, I wish to show that a lack of an advanced knowledge of mathematics need not stand in his way. The proper position of the study of physics in a curriculum is not difficult to settle. It must be at the beginning, and it is a matter of no importance what it is called — it may be part of a preliminary scientific training, or it may be the beginning of the medical course — it is enough if it be there. But this raises the question of what the preliminary training of a medical man should be — a question of extreme importance in these colonies where medical schools are young, and, like other young things, plastic, because free from the trammels of use and wont; and largely free also, though unfortunately, from the influence of a medical public opinion — an influence, the absence of which on many grounds,, is gi-eatly to be deplored, but a contribution to the creation of which will, I trust, be one of the chief results of this Congress. The question takes us even further back — it takes us back to the school training. I confess that I am not sure how far the teaching of what is ordinarily called science may be introduced into primary schools, but I have no hesitation in saying, that some measure of elementary scientific teaching should be given to all cliildren, without distinction. To the boy who will afterwards get such teaching at the University, where, in all likelihood, he will begin at the beginning, it is not a matter of such moment; but for the great majority of boys, who will jiot get any instruction at all in natural science if not at .school, it is a matter of the very greatest importance. Of course, what I say of boys, I say equally of gii-ls. It is unfortunately the case that, as yet, the best teachers are nearly all literary and mathematical teachers, and consequently, the Ijest teaching is still exclusively of a literary and mathematical nature. So long as the teaching of natural science in schools is a sort of extra thing, done at odd times, done in most iusufticient measure and too often in an inetticient manner; .so long as the study of letters and abstract mathematics thus completely overshadows the study of everything else, so long must the pre.sent unsatisfactory state of matters continue. In parenthesis, as it were, I would strongly urge the teaching of drawing to every child in the school. I do not necessarily mean 572 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. more than the drawing of a straight line, of a good curve, of a proper angle, and such like, so that in after life, ideas may more frequently be conveyed by figures instead of by words only. The efficiency of this description by pictures, as a training of the faculty of observation and of the mind, is not, I think, questioned in theory, though sadly neglected in practice. The ancient Mexicans — -a wonderful race — had no other mode of recording ideas. I would likewise urge the more frequent training of children in the art of verbal description. All sorts of objects should be placed before them, and they should be required, after due observation, to write down in words just exactly what they find. Such an exercise would be at once a training in observation, in composition, grammar, spelling, and writing. All teachers of science complain of the many young men and women who come to them with their eyes wide open, and yet seeing nothing whatever. This faculty of description is in a large measure to be acquired by practice, as every teacher of anatomy can testify. The New Medical Curriculum of the University of Sydney. Amongst other things, we have secured for students the training in physics, of which I have spoken. Sydney, as regards the medical curriculum at least, is now well in the van of progress. Thus, in Australia, we were thinking on the same lines as they have been in the United Kingdom. The time is evidently ripe for the change. Here, we had carried out, what there they are still only thinking about. Perhaps I might be permitted to say a word on the curriculum which we have striven to make as perfect as practicable, and which — as finally passed by our governing body only last month — is, of course, probably the latest thing of the kind. As a giiarantee of a sufficient general education, we require a degree in arts or in science, or failing a degree, a year's attendance on the classes of the first year of the arts course, together with the examina- tion at the end of that year. As an alternative, we have now as an entrance examination, certain subjects of the Senior Public Examination. After this follows a course of five years' duration. The student is mainly concerned in the first year with physics, chemistry, and biology ; in the second and third years with anatomy and physiology ; in the fourth and fifth years with the more special departments of medical science. In every department, practical instruction is insisted upon. It is our desire to educate and train, rather than merely to instruct and cram. Further, we recognise that, while examinations of some sort are necessary, they are not an unmixed good ; and in our practice, we have to some extent anticipated the remedies suggested in that much-needed president's ADDRESS — SECTION OF ANATOMY AND PHYSIOLOGY. 573 signed protest, and the accompanying comments, published in the November number of the Nineteenth Century. We try to minimise the evils of the examination system as follows : — In the degree examinations, the results of the class examinations, which are compulsoxy, and are conducted during the course by the teacher aloiie, may be taken into account ; there is an interval of two years between the first and second examinations ; the teacher is co-ordinate in every way with the associate examiner ; in every subject a practical or vivd voce examination follows the written paper ; there is no separate honours examination — honours depend on the high excellence of the student throughout his whole career. We have made compulsory a course of ophthalmic medicine and surgery, and a course of psychological medicine. Requiring attendance on a course of instruction in logic and psychology, is a new feature. Thus the student becomes acquainted systematically with tlie general methods of science — with, as it were, the grammar and syntax of science, and is introduced to many of those problems of philosophy which have occupied the minds of men in the past, and which, from the nature of his daily work, can hardly fail to occupy his own. Also, by making it part of the Bachelor's course, we avoid that annoyance so often experienced by the Bachelor proceeding to the Doctorate, when he finds that he has still to pass in logic at a period of life when such examinations are peculiarly distasteful. These are steps in the right direction, which I am bold enough to commend to the attention of the General Council of Medical Education and Registration, and of most British licensing authorities. Another point worthy of notice here is, that at the end of the first three years of our medical curriculum, the student can, with some extra work, obtain the Bachelor of Science degree. The science and medical curricula are now made practically identical as regards the first year, and we reckon that the next two years' medical study will, with some additional and advanced work, make up the requisite three years' work in science, so that the best and most industrious students of medicine can acquire a degree in science. We thus seek to emphasise the fact, that the earnest man of medicine, is a man of science in the truest sense of the term. The Improvement in Teaching Methods. Nothing, I am frequently told, strikes men who have received their teaching in the not very distant past, so much as the great care that is now taken to see that every student, in each department, shall have the maximiim of practical work and the relative minimum of book work. The illustration of lectures is now carried to an extent before unheard of. I have heard it remarked that we make things too easy for students 574 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. noAvadays. I cannot think that ; for with the advance made in teaching methods, there has been an enormous expansion of the subjects in every direction. I think we may assume that the best text-books contain a statement of what is fairly established. On this assumption, an examination of some of the standai'd text-books is very instructive, as showing the rate and extent of the expansion of our sciences. Thus " Quain's Anatomy " was first written by Jones Quain alone; in the later editions, there are always three editoi'S. The third edition, in 1834, had no illustrations, and only 467 pages (when its actual 855 are reduced to the present standard); the sixth edition, in 1856, had 356 figures in 1096 pages (its 1635 being reduced to the present standard); and the last, the ninth edition, in 1882, has 1194 figures in 1617 pages. Some Account op what Anatomy and Physiology have been Doing during Recent Years. "While the influence of the doctrine of evolution has extended to every department of knowledge, it has influenced our own branches of science more directly than any other, and to it we owe much of oiir progress. It is as pre-eminently the working conception of anatomy, as the law of the conservation of energy is now that of physiology. The progress of physiology has led to that of preventive, as compared with curative, medicine; and though the modern system of preventive medicine is only about forty years old, its development is now the great and high end of the efforts of medical men. The triumphs of sanitary science are now to be sought in every clime — in the barrack and in the field, in hospital construction and in hospital nursing, in the sanitary arrangements of the house, of the city, and of the entire community. In this connection, it is greatly to be deplored that the Legislatures of the world — not of these colonies only — do not see it to be their duty to do more in the way of sanitary legislation ; for, as has been so wisely said, the best way to make a people happy, is to keep them healthy. This advance in sanitary matters has been greatly aided by the spread of natural knowledge amongst the people, by their greater disposition to ascribe their troubles to natural and often })reventible causes, rather than to wholly inevitable workings of an unseen power, whether good or bad. In curative medicine, physiology, through pharmacology, has played a great part lately, and is playing a greater part every day. Pharma- cology, i.e., the precise knowledge of the mode of action of drugs and other influences affecting the organism — rests almost solely on physiology. But on the other hand, physiology owes much to the younger science. From pharmacology, indeed, everything is to be expected. Huxley, in his address before the London Meeting of the PRESIDENTS ADDRESS — SECTION OF ANATOMY AND PHYSIOLOGY. 575 International Medical Congress in 1881, said of |)liarmacology : — " There can surely be no ground for doubting that, sooner or later, the pharmacologist will supply the physician with the means of affecting, in any desired sense, the functions of any physiological element of the body. It will, in short, become possible to introduce into the economy a molecular mechanism which, like a very cunningly devised torpedo, shall find its way to some particular group of living elements, and cause an explosion among them, leaving the rest untouched." A perusal of Lauder Brunton's " Pharmacology, Therapeutics and Materia Medica," tends to convince one that the goal is nearer than many think, for it is becoming clearer that there is a very close connection between the physiological action of a body and its physical characters, such as its •chemical constitution, its atomic weight, and its spectrum. To{)Ographical anatomy has made such strides quite lately, that its arty wall had become obliterated, and resulted in the formation of one large cavity. I only remember reading of one similar case, reported recently by Mr. K. Thornton. FIFTY CASES OF ABDOMINAL SECTIOX. 651 Case 50. — This patient was a woman,. who gave her age as 62 years, but probabl}' older. On ojiening the peritoneum, the whole abdomen was fjlled with layers of jelly-like material, which dipped between the bowels and different viscera. On clearing away some of the surface jelly, a white ovarian cyst was found, with a large rent, through which the colloid material had esca})ed into the general peritoneal cavity. In Case 65, a similar accident had occurred, the peritoneal cavity being filled with colloid material, considerably modifying the ordinary lines of resonance on examination prior to operation. In both ■ these cases, the syphon trochar recommended by Lawson Tait was employed, and acted most efficiently — gallons of hot water were thus syphoned into the peritoneal cavity, block after block of glutinous jelly-like material floated up out of the wound, until the })eritoneal cavity was thoroughly cleared out. Both these patients made most satisfactory recoveries. Another point to which I would draw your attention in this list of ovariotomies, is the frequency with which more or less abundant traces of dermoid materials were observed — in seven of the eighteen cases was dermoid matter distinctly present. Those who are interested in the subject, and have not read an article in the last number of the Gi/mecological .Tournal, by Bland Sutton, on the "Origin of Ovarian Dermoid," will find it well worthy of careful perusal. In it, he points out : — (1) How multilocular, ovarian, and dermoids, originate in Graafian follicles. (2) How frequently dermoids are associated with multilocular ovarian tumours. (3) How transitional stages can be traced from the membrana granulosa — the lining membrane of the follicle — to mucous membrane; then to mucous glands, of which multilocular ovarian are composed; then that skin and mucous membrane are fundamentally identical. Skin covers the exterior of the body, has sebaceous glands, and is furnished with hair; and if a complex cyst, such as a multilocular ovarian, can aiise from a Graafian follicle, surely we cannot deny the origin of an ovarian from the same source. In this manner, accounts for ovarian dermoids in a much more satisfactory manner, than by the vague hypotheses formerly held. Under the heading. " Tait's Operation," are classed cases where the Fallopian tube pre.sented some marked inflammatory change, where this iiiflaumiation had extended to the neighbouring peritoneum, and where the ovary was more or less bound down by adhesions. The operation for the removal of the.se diseased appendages has been by far the most diflBcult I have performed within the abdomen. Throughout the ojieration, one has to depend solely u|)on the sense of touch. The relations of parts are often much altered, the structures themselves olianged often beyond recognition, the ovary more than once entirely >hut off by layers of exudation. The i-esult of my cases has ])roved to me, what an immense amount of manipulative interference the peritoneum will stand, provided no 652 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. visceral injury is inflicted. The incision through the abdominal walls, in these cases, must be made with much more care and deliberation than where the abdomen is distended by a large cyst. More than once have I found the peritoneum beneath the line of incision, thickened and adherent to underlying structures. The fundus uteri, which is generally taken as a guide to identify the tubes, was in Case 55 so surrounded by adhesions to neighbouring bowel, that it was with difficulty reached; the adhesions of the tubes and ovaries to surrounding structures are often so dense, that considerable force has to be employed to separate them; and more than once I have feared a rupture would occur into the neighbouring viscera, or that some of the main vessels would be torn. In Case 40, .such a ruptui'e into the bowel did occur ; and a subsequent post-mortem showed several points of ulcerative com- munication between an enlarged caseating cavity in the Fallopian tube and the descending colon. In both cases of this operation that terminated fatally, the disease in the tube was tubercular. In Case 40, the general peritoneal cavity was inoculated throughout ; the tubes were converted into large caseating masses, and the left had formed adhesions so dense and extensive, that the attempt to remove it had to be abandoned ; and even at post-mortem it was found impossible to remove diseased portions, without actually stripping the whole of the left and posterior part of the pelvic cavity of its contents. Even here, however, the broad ligament could be identified, displaced and covered by adhesions, but no thickening or deposit existed between its layers. In my second fatal case. No. 56, some rupture into the urinary passages must, I fear, liave occurred during operation. The case was one of old standing ; the adhesions were unusually tough and dense, their solid irregular feel having led to a diagnosis of cancer by the gentleman who had forwarded tlie case to me. Blood was drawn off with the urine ; following the operation, peritonitis and collapse ensued ; the abdomen was drained, but no improvement followed, the patient dying on the third day. Dr. Roberts made sections from the diseased tissues, and found typical giant-cells of tubercle. In Case 54, the adhesions between the right Fallopian tube and the bowel were most intimate, and required most careful dissection for its removal ; and if it had been permitted to run on, a communication between the two must shortly have occurred. Ileviewing this class, I should say that the operation is severe proportionately to the nature and extent of the adhesions. The symptoms to which the disease gives rise are also severe, and often render invalid, or eventually even cause death. Operative measures give the only prospect of relief, especially to that class of patients to whom the struggle for existence renders work imperative. The risks of the operation itself should be by no means greater than other operations performed for less serious conditions. It is an operation we therefore hail as a great addition to our resources, and the greatest advance in modern Gynaecology. Oophorectomy has been performed for two different conditions : — (1) To arrest growth of fibroid tumours. (2) For severe ovarian pain, causing marked reflex disturbance. FIFTY CASES OF ABDOMINAL SKCTIOX. 653 Oo])hovpctoinv, for arresting; growtli of filiroids, is not so easy as one might at first siglit imagine. The fibroid is often twisted on its transverse axis ; the position of the ovary difficult to discover, especially through a small abdominal incision ; the pedicle is very short, and difficult to drag into the wound, and the veins of the broad ligament enormously dilated ; although I have not lost a patient. Case 25 had an attack of phlegmasia dolens following operation, which i-etarded recovery. In all four cases, the growth of the tumour has been arrested. In Case 16, the lu^morrhage, a troublesome symiitom, continued as severe as ever, when I last heard of the patient. In Cases 25 and 33, the haemorrhage was arrested, and the tumours decreased remarkably in size. In Case 25, although prior to operation the summit of the tumour reached two inches above the umbilicus, eight months subsequently, the outlines could only with difficulty be made out immediately above the symphysis. Case 28. — The fibroid was small, and tending to grow towards the right side of the pelvis. The menorrhagia was effectually controlled, liut the patient's condition has been rather aggravated than improved by the operation, so severe have been the climacteric disturbances. For twelve months, flushings, headache, and general debility were the chief complaints. Latterly, })alpitation and polyuria, amounting to twenty pints a day, and other sympathetic disturbances. On the whole, I am not satisfied with the results of these operations for arrest of fibroid ; and from a somewhat limited experience of the Apostuli method, by large doses of galvanism, should certainly give it a trial before resorting to oui)horectomy, or severer measures. With regard to oophorectomies for persistent and severe ovarian pain, I must honestly confess that, with these cases, I have always felt myself treading on dangerous ground. I have avoided opei-ating in a good many cases where some surgeons have considered the indications sufficient to justify this radical measure. My difficulty has been in determining where the subjective symptom (pain) is due to a change which, by examination, gives no physical sign, and those cases where pain is merely an indication of some general nervous condition, localised specially in the ovary by some morbid concentratioii of the mind on the generative organs ; or some slight local irritation which, with a more healthy state of the nervous centres, would not cause any appreciable disturbance. In the few cases where I have removed ovaries on account of pain, I have failed to find sufficient change to account for the symptoms. I entertain the gravest doubts as to the role that slighter form of cystic conditions play, as a factor in the production of symptoms. I have more than once seen an ovary containing cysts in abnormal quantity and size, without giving rise to any symptom whatever. In the early stage, too, of the ordinary forms of cystoma, there is, more frequently than not, an entire absence of pain. When we perform an operation which mutilates and destroys one of the most important functions of womanhood, I must admit, that I am materialistic enough to expect to find some change marked, evident, and ready of recognition by the naked eye ; and that the same rule must apply to the ovary, as to any other imjiortant organ in the body, viz., that before removing it, it 654 INTERCOLONIAL MEDICAL CONCxRESS OF AUSTRALASIA. must be hopelessly diseased, and the changes gross and characteiistic. Until, however, we obtain a closer insight into the histology and pathology of the ovary, we must expect to find radical differences in opinions and practices. In Case 49, when I removed a prolapsed right ovary, which contained cysts in excess, it would have been better practice to have fixed the ovary in normal jjosition, and not removed it entirely, as I did. In Cases 53 and 54, excessive cystic formations were present in the ovaries. The pain, constant and jjersistent in one case, was entirely removed; and in the other, the reflex ocular disturbance entirely subsided, but the conjecture must ai'ise — had these patients' social surrouiadings been different, had they been in a position to undergo a course of Weir jMitchell's treatment, or had they become pregnant, might not the results have been equally good, and at a less cost. The operation for removal of cystic or cirrhosed ovaries is by far the simplest in abdominal surgery; and it is hardly fair to class these cases with Tait's operation, where one frequently meets difficult and dangerous complications, and where there must be a much heavier mortality. The mere fact of the operation being so easily performed, and being attended by so little danger, renders it a measure specially liable to become alaused. The two cases of extra uterine fcetation, I have already repoi'ted in full. No. 14 was at the earlier month of pregnancy, and the cyst had apparently ruptured between the layers of the broad ligament. No. 19. — The pregnancy was probably originally tubal, and had burst as usual about the third month into the general peritoneal cavity. The foetus continued to develop till term ; its death occurred, and for some twelve months it remained in the abdominal cavity, without causing any disturbance. Communication then occurred between the sac containing the foetus, and the bowel, and decomposition set in, with symptoms of septic absorption. By operation, a decomposing foetus was removed. Both these cases made satisfactory recoveries. Laparotomy, during pregnancy, was twice performed : — Case 4, was removal of a cyst (hydatid) from the under surface of the liver, by an incision on the outside of the right rectus muscle. Case 21, was a case of strangulation of the bowel, from bands; the patient was almost moribund during operation — a most desperate case. Both patients made most satisfactory recoveries. Pregnancy in each case had advanced to between tlie third and fourth month; in neither was its normal course interfered with. Both were delivered at full term of healthy children. Hysterectomy was performed in four cases : — Case 15 was a moderate-sized tumour of slow growth, causing severe menorrhagia. The fundus uteri reached to the cartilage of the ribs on the right side ; the adhesions were numerous and tough. An interesting point in connection with this case is that, when first admitted into the hosi)ital, the tumour was diagnosed malignant, on account of oedema of the legs, ascites, and a large effusion in the right pleural cavity. The chest was tapped, and the patient left the hospital relieved. Six months FIFTY CASES OF A15D0MINAL SECTION. 655 subset) uently, slie was i-e-atlinitted, on account of the increasing size of the abdomen ; and as her general health had in no way deteriorated, and there was no reappearance of the pleuritic effusion, 1 determined to make an attempt to remove the growth, which I succeeded in doing, treating the stump by Kceberle's clamp. The })atient made a good recovery. Case 22. — An enormous fibroid, distending the whole abdomen, and causing anajmia, from menorrhagia and constant irritating Avatery dis- charge. Drugs had no effect, and intra-uterine dilatation and applications failed to arrest haemorrhage. The entire uterus and appendages were therefore removed, and the extra-])eritoneal stump clamped, as before. The patient made a thorough recovery, though for many days her life hung in tlie balance. A free purgation, finally, I think, determined matters in her favour. Case 35. — A ]:>articularly distressing one. A young woman, set. 2H, only confined of her second child a few months previously, developed malignant disease in the uterus, which must have rapidly involved the whole organ. When I first visited her, she had only complained six weeks, yet there was a large fungating mass protruding through the cervix. The body of the mass was irregular and nodular, and infiltra- tion was evidently extending in the broad ligaments. A microscopic examination of a section from cervical tissue showed alveolar structure of scirrhus, and consequently it was determined to make an attempt at removal. In consequence of the broad ligament being involved, it was determined to operate through the abdomen. The mischief was found to be even more extensive than had been anticipated ; the whole uterus, a great portion of the broad ligament, the Fallopian tubes, and ovaries, requiring removal. The stump of the broad ligament was ligatured, the abdominal wound closed, and a large drainage tube inserted through the vagina. The patient for three days sviffered severely from shock, but subsequently made a truly remarkable recovery in ten days, being freer from pain and in better health than she had been prior to opera- tion, there being an entire absence of any constitutional disturbance. The disease, however, rapidly recurred ; and shortly she succumbed, large masses of cancer blocking up the pelvis. It is somewhat remark- able, that six months previously, I had removed an ovarian tumour from this patient's sister. Case 51. — One of the most interesting cases I have met with in abdominal surgery. The patient, aged 22, a strong, muscular woman, was admitted into the Dunedin Hospital with a history of a miscarriage at the fourth month, two weeks pi-eviously. Since then, she has been excessively ill, losing flesh, unable to take food, confined to bed, and suffering heavy losses of blood. On admission, the patient was blanched, suffering from metrorrhagic discharge, with an irregular temperatui-e and quick pulse. The uterus was felt enlarged to the level of the umbilicus, hard, and excessively tender. In consequence of the history of miscarriage, it was considered probable that there were some placental remains in the uterus ; and consequently it was dilated and its cavity examined, but nothing was discovered beyond the fact of its being too large, and though the whole finger was introduced, it did not reach to within an inch or more of the fundus. After this, the metrorrhagia ceased, but the abdominal 656 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. tenderness, fever, and constitutional disturbance continued. The anaemia became daily more marked, and it was suggested that we were dealing with a case of pernicious anaemia. An examination of the blood showed the red corpuscles irregular in outline, deficient, and large quantities of granular matter, and small corpuscles. By abdominal palpation, the tumour was found to be increasing in size, the bulging being especially marked on the right side, whereas the sound passed to its greatest depth towards the left. On visiting, one day, it was found that the outlines of the tumour — which had been carefully mapped out with aniline the day previously — had made a very remarkable increase in all its dimensions, and the margins were softer and less defined. The patient's condition was worse, being more ansemic than ever ; it was thought that possibly there might be some heematic effusion. A needle was passed on several occasions for diagnostic purposes, but gave no further information. An exploratory incision was therefore made. On getting through the abdominal walls, the sub-peritoneal fat was cedematous ; the peritoneum itself thickened ; on opening it, semi- opaque fluid spirted from the opening, and a firm fleshy tumour came into view, part covered by flakes of lymph, pai-t by a greyish exudation, and part black and gangrenous-looking. To the summit and posterior portion of the tumour were attached neighbouring bowel and omentum, in separating which, several separate accumulations of fluid were opened — some consisting of clear serous, some semi-purulent, and some purulent fluid. After clearing the whole mass, we found that the portion to the left consisted of a large sub-involuted uterus, while springing from its right side was a sloughing semi-gangrenous fibroid, larger than a good-sized cocoanut. It was evident that the woman's only chance lay in removing the sloughing fibroid, and with it the uterus. This condition not having been anticipated, I was not prepared with the clamp I have previously used in my hysterectomies; and therefore adopted the plan of clamping the broad ligaments separately by long forceps, and then amputated the uterus close to its neck by a circular flap, taking care to cut the exterior layer of uterine tissue at a higher level than the inner. Smart bleeding occurred from some vessels at the root of the broad ligament, which had not been included in the clamp, but it was quickly arrested by application of Spencer Wells' forceps. The tissues of the stump of the broad ligament were then separately ligatured, and all bleeding controlled. The uterine stump was united by double layers of suture — the deep taking a good grip of the muscular wall, and the superficial including only the peritoneal tissue — a very good stump was thus obtained. After freely syphoning the ])eritoneal cavity, and inserting a glass drainage tube, the abdominal wound was closed. For the first week, all went well ; little discharge coming from the drainage tube, and temperature and pulse improving. Then symptoms, of intestinal disturbance arose — flatus, vomiting, and twisting pain in the bowels. The upper part of the wound, two inches above opening for drainage tuVje, became distended and hard, and here I had to make a counter opening, evacuating pus in large quantities, and subsequently bowel matter. A cavity formed here as large as a small orange, the floor being formed by convolutions of the bowels, in one of which a FIFTY CASES OP ABDOMINAL SECTION, 657 circular opening existed, through wliich the intestinal contents discharged. This oi)ening was evidently high in the intestinal canal, as food escaped through it almost as taken by the mouth. Tlie patient gradually sank. At post-mortem, two feet of the small bowel was found to have become invaginated ; the intussusception had started by a portion of the bowel being constricted by adhesions, the result of the previous purulent peritonitis, and sinking within and becoming strangulated by a larger and more patulous portion. The sudden enlargement in the outline of the tumour was probably due to the ojdematous state of the peritoneal tissues surrounding it, and possibly also to exudation in the tumour itself. In this case, a purgative was administered on the fifth day, which I have since regretted, as it may have had some influence in producing the intussusception, and it was unnecessary, as the peritoneum was well drained. Case 43. —This case of Cfesarian section opens a very large subject. The patient, a primipara, fet. 32, had been in labour three days ; the os had been fully dilated, and the membrane ruptured many hours. On visiting her, in consultation with Dr. Roberts, I found the patient a stout muscular woman, who was evidently becoming exhausted. The vagina was dry, rigid, and undilatable; the os was high, the pelvic cavity being very deep; it was only by introducing part of the hand that the presentation could be determined. Forceps had been applied, and re-applied, and failed (brow and hand). The uterus was in a state of tonic irritable contraction. An attempt was made to turn, but utterly failed. It was impossible to convert the case into vertex. Chloroform was administered to deep anaesthesia, but no relaxation of the uterine walls ensued. Our choice lay between craniotomy, which with rigid undilated vagina and deep pelvis would be aia exceedingly difficult and prolonged operation; and in patient's weak state, dangerous, involving much laceration of soft parts; or Caesarian section, which we considered finally would give a little chance. The operation was performed on a table, in as good a light as we could command, in a small room. The uterine wall was freely incised, keeping away from cervical portion. The child was so tightly grijDped by the uterus, that in incising the uterine wall, we also scored the skin of the child's back. The child (dead) was extracted with difficulty. Haemorrhage from the placental site was quickly arrested, but a large sinus from the lower part of the uterine wound bled pi'ofusely, and was the cause of much delay in closing the wound. Deep muscular and superficial peritoneal sutures closed the uterine incision. The patient never rallied from the operation, but died shortly after removal to her bed. Now to make a few references to the steps of the operation itself, in addition to the preliminary preparations usually recommended. In all cases where I have to open the abdomen, and expect to find changes in the pelvic organs, immediately prior to Operation the vagina is rendered aseptic by thoi'oughly washing out with sti'ong tincture of iodine in solution with hot water. In cases of difliculty, I have gained much by passing one or two fingers into the vagina, while the fingers of the other hand work in the abdominal cavity. When the tubes and ovaries lu 658 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. are much bound down by inflammatory products, the assistance thus gained is immense, and but for this manoeuvre, I should have been unable to complete several cases of Tait's operation. In making my incision through the abdominal walls, I always avoid dissecting the tissues as far as possible ; the first cut usually divides skin and fat down the muscular walls, the second divides the sheaths of the muscles for the length of the wound. On reaching the sub-peritoneal fat, especially in cases where there has been peritonitis, I find it neces- sary to be exceedingly careful, much more so for oophorectomies than ■when dealing with large cysts. To divide the sub-peritoneal fat cleanly, a very sharp kiaife is required, otherwise it slips under the blade, and the fat is notched and jagged irregularly, which intei-feres with the subse- quent kindly healing. As soon as I have opened the peritoneal cavity sufiiciently to admit the finger, I trust to it rather than to directors (from non-observance of this rule, I once saw an operator seriously injure an adherent coil of bowel). For emptying a cyst, I now always incise freely with a sharp-pointed bistoury, turning the patient on her side before so doing, and directing one of my assistants to seize the cut and gaping edge with strong catch forceps. I prefer this infinitely to tapping with a trochar — the latter, being often blunt, fails to penetrate a thick cyst-wall cleanly ; the cyst often tears near the trochar, and permits an escape of fluid ; the tubing is apt to kink, or get clogged, if contents of cyst are thick, if a multi- locular cyst is being dealt with. To open secondai-y cysts satisfactorily, one must eventually, in most cases, open cyst- wall sufiiciently to introduce the finger and feel for projecting cysts. For ligature of stump, I employ the Stafi"ordshire knot, as advised by Lawson Tait. If thick silk is used, it should be well saturated with wax, or otherwise it will fail to run freely, and causes trouble. The syphon apparatus, recommended also by Lawson Tait, I have found invaluable in several cases. Where colloid material has escaped fi'eely into the peritoneum, it would have been simply impossible to have cleaned that cavity effectually, without employing some such measure. With a large tube, the pei'itoneum can be flushed with gallons of water in a few minutes ; colloid matex'ial floats out of the wound ; much time is thus saved. It avoids a large amount of sponging and manipulating within the peritoneum, and one can do with far fewer sponges. I have several times completed an ovariotomy, and employed only two or three sponges throughout. It is a mistake to have too many sponges in use ; they are apt to get mislaid amongst the patient's coverings, or in dirty solutions, and at completion of operation cannot be found. I always have a supply ready, but direct the assistant not to use more than is absolutely required. For sutures for abdominal walls, I use strong silkworm gut, and include the whole of the tissues of abdominal walls; they are more easily removed than silver wire, and are equally clean and strong, and will remain for months in the wound without dissolving. The necessity for carefully counting sponges and forceps, prior to closing the wound, has more than once been xmpleasantly brought home to me. Once, after a severe and difficult operation, I neglected this usual precaution, and on getting my instruments home, found a forceps missing. I had almost decided to return and open the wound, when FIFTY CASES OP ABDOMINAL SECTION. 659 •on enquiry of the gentleman who had administered the anaesthetic, I found lie had inadvertently enclosed it in the bag with his anajsthetic apparatus. [ employ very simple dressing for the wound. After adjusting sutures and drying surface, it is freely dusted with a powder, composed of one part of finely powdered iodoform with four of amorphous boracic acid. A light layer of absorbent or alembroth wool is laid on this; a broad strip of straj)ping, which encircles the fourth of the body, keeps this in place, and supports the wound in case of vomiting. A large pad of absorbent tow covers the whole abdomen, and a many-tailed bandage is applied over all. When possible, I do without drainage tubes. The proper place for draining of the peritoneum is, I consider, the posterior vaginal fornix. In the majority of my cases, the jiatient is advised to pass her water without the assistance of the catheter. A few hours after o])eration, if the patient prefers it, she is allowed "to lie partially over on her side, supported by a pillow along the spine. On the third or fourth day following operation, a purgative is generally administered, especially if there is a foul breath, furred tongue, vomiting, persistent distension, or other sign of abdominal disturbances. Opium, if possible, I carefully avoid ; some administer this drug as a mere matter of routine; some immediately any symptoms of peritonitis are apparent. There seems to me little likeliliood of this drug being of any xise in the form of peritonitis we most dread after operation in the abdominal cavity, viz., purulent peritonitis ; and my impression is, that the strong recommendation of the administration of opium, in the treatment of pure peritonitis, depends upon a confusion of ideas and expressions. Peritonitis, as met with in general practice, almost invariably depends upon ])re-existing visceral lesions, and for such visceral lesions opium stands pre-eminent amongst drugs ; but it is illogical to argue that it is of equal applicability in peritonitis, independent of such visceral complications. In fact, in dealing with a pure peritonitis, my belief is that opium does much harm by masking symptoms, and rendering adhesions, when they do form, more dangerous. Vomiting has always been my greatest trouble amongst minor complications. I know of nothing that I can depend upon for its relief. As a rule, for two days no food is administered by the mouth. A little scalding water, sipped now and again, is all I generally allow. Ice is avoided, as it induces thirst. Occasionally, when there is much shock, an injection of morphia will temporarily allay sickness. lu 2 660 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. 5 o (M CO -* »c I-H OJ CO '^ >0) 1 o 00 o-l § I-H I-H T-H I-H 1 1-H t-H !§^n s ^" ^ p « H 03 ^ Si 1 Sh cS Ed s s pi ^ ca oi t> > o ft P- > t> > o O .3 s s •S O o^ o o o o OOQ a 'm OJ 'm a a a a a a ffl "S A S K K Ph « m O P5 "o (D to (D N _o _N 'S ^- 'cQ to ^ Xfl aj o fl g ® o 'm o > a O ft o CO frJ "^ rfl 1" Is CO p a a ft a i 1 a ^ >» 9 CQ V g 1 Ii § a .3 fl >1 •1 "c3 o O > a 3} s "S a 2 1 p O tn CQ o o ft m S -si S O U tH M TJH O CO CO (M ira C^ 1 o » o <1 ^ CO CO 00 CO OJ CO CO (M 1 CO S<1 WH f^ d H^ M w w i4 M m 1 CQ g s pq W S z s H^ S S 1 S" CQ O 00 t- i-i o US ■* I-H i-H « 05 u ^IN (N"-" CO "^ (M -t< (M I-H i-H lO «D (M -< ggg ^t "ft 00 ^ l> 00 . 00 p to ft 00 00 00 . 00^ ^ P '-^^ >H (li a> o '^ c3 a I-H iH gj ■s ;Z5 ■al S 02 l-^ iz; 1-5 < CQ Pt, i-s sis »H c-i CO Tl< Ui o t- 00 05 O o' 2 S iH !^£^ FIFTY CASES OP ABDOMINAL SECTION. 661 ^"« o a O 3 9 a 3 a I 3 2 a Ph o ft O O o Q O o O o U o o rrSrQ o d< a a ri CS e § !3 g 't> g3 Q _g "3 . O o ^•1 g ^ 1 1o ■cS a o g ■■8 1 ■§ o "o a _o 3 o o g O ,a a O g o p o ra CO s o -a 0) a ^ CO * ca^ > a ^ o.a -;s g o o >i "S, Ol i 8 o a Cm db .9 o CO C3 a fcD d g "3 g g CO CO a o g <0 1 "3 a o o a _o 1 CO a a cS O -^ >. _a to . a* _o 3 .3 0) < M c o H a s H < O O a a > O a to a 6 S ^ a O tJD CO 0) g a _a CO S 'tJD c3 ra o a o a CO 6 i CO cS g o g 6 a CS ,a O a g to CO cS > o o CO c tc cS a cT o Q & a P _N 3 a CO to _a O 3 CO It -2 ^ « g „ o M a o 'o a o a o > o > CS a 2 tD C3 a o a o d CS 0) CO li a p -a a . o ^ 11 'Ec' g 1 2 c=a o CO g a _3 1 3 c3 CO c3 1 a o o ^ 3 o '<~< ^ ■^ "3 g CO "cS 3 H 1-q o 3 ft 6 £ S 02 s s s O O 00 -* t~ o C5 ^ CO o 'I* !>• 00 o CO «5 • > > t=^ O O o sj 0) a< a tu o o o o o O O •^ l-B P4 <3 t-B CQ O IZi ;z; iz; :z; sis c-i CO — H •« — c- GO Ci o I-H (M CO -*i o " S 1-1 rH rH r-t 1-H I-H Ol 0^ O? (M C^l a*^ 6G2 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. loas a5 a5 ,:^ aj 0) aj oj « o c3 S pi ai ^ r- 3 S 13 o U P a ^ O U o O o r3 O « ^ g :;^ a ^^ rt o ij * a H rt H rt °o i ^ o « P3 s g ci & >• O >4 N «: 1 p ® oT P< ■i §2 c3 153 ^ a .. -;S s 2 ... g.2 w a: SD tp.^^ O cS a S 6 >3 n^-^ •5 ?^ a> cS ^-73 OJ <-< n gj a cj O S o = «^ ^ cS ca-i^ a '^ &i a. 5 r-* .,. OJ a> rH ^ tc a: S"^ M *r" , , o a T! a oi a "S 0) 0-. O o3 56 o S *^ ft fi S , — > -^ U2 ^ £1. ci rt s .a p^ ;L4 >i > g O IK I- ^ ^ '3 oj ;S -a "- CC tj C£ ^ « O ft o < ■ t^ oi O CO CO o CO CO CO CO 00 CO § CO 00 IN m 00 q ^ g S S n lO »« •0 «o CO CO CO CO CO 5 ^ ^ o 9 oj P -< U 0) 3 d 3 a J3 3 3 a « o O o Q 6 U u Q 6 6 a c^ _o ;-( a, Ol J S "S CM '" '-^ 1 ••■ QJ . a* a a a C a >1 a o a _o ,0 Id "t? QJ c o 1- "S o a, ID Pi a "3 "^ 1 "S o CO rx. j/i ai g m m 3 :o 'cS '3 '3 ■3 3 '3 '3 S 0) Ol W O O H H H H Ph H H M « p^ c3 "3 3 CO a a a .60 "72 a a m ^ |-~] _o o a "3 a. d ^ a 5 CO o it a> CO g tp C3 .2 o 03 _o ^ -t-i g "S H '3 o O CO CO '33 3 3 .'a 2 •< U o p4 ^ c3 ■3 a .„ ri> '0 3 CO a 5 O « p < iz; "a S p "a CO o o a 2 u CO o ,0 a CO to c3 a a C3 s en "cS 8 3 a to CO 0) to Is a g 3 ta _a CO to 0) tJD 60 in ■2 i a TS cS cS c3 03 2 to a '3 Pi o 3 a, a< ■ eg Ol CO cS a (U Pi P4 a Ol a a- cS 3 a Ph Pi 03 3 a 3" 11 a a a a a rw 0) '« > 0) CO CD ^ a> 3 >

t» > M O O s « S Q ft s u o < (M eo ■^ t- «5 CO IN »« -rH CO (N 10 « i (N cq i > Ol s < -< iz; ;« 'Z « Q « i *gg III 00 o o i-H iM CO -*< "o t^ 00 as 1 M cr. ~^ tt tX '^ -i< ■^ '^ ^ ■>«' »o 664 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. TWO CASES OF EXTRA-UTERINE PREGNANCY, SUC- CESSFULLY TREATED BY ABDOMINAL SECTION. By Ralph Worrall, M.D., M. Ch. Hon. Assistant Sm-geon to the Department for Diseases of Women at the Sydney Hospital. At the present time, no subject in Gynaecology is more energetically discussed than that of ectopic gestation. I have, therefore, thought the record of two cases a not unworthy subject to bring before this Congress. The first case was that of Mrs. W., set. 33, married fifteen years, four children, last in January 1887. This labour was diflicult, and convalescence slow. A slight red discharge appeared off and on for three months afterwards, and then completely ceased. About seven months after confinement, she noticed a small lump in the right inguinal region, which was painful on exertion. She felt queer, but did not know whether to consider herself pregnant. She was nursing the baby, and, therefore, was not surprised at the absence of her monthly periods. On September 27, whilst washing, felt a sudden severe pain in the small tumour, and spreading from there all over the abdomen, causing her to faint. She was carried to bed, and revived by brandy. In about two hours vomiting set in, and the faintness passed off; but the pain continued to be very sevei-e. The patient was first seen by me on the following day, September 28, and then presented the local and general signs of acute peritonitis. Bimanual examination disclosed a tender fluctuating swelling, 2)rojecting into the right vaginal fornix, displacing the uterus forwards and to the left, and reaching above nearly to the umbilicus. For the next five days there was no change in her condition, except that the acuteness of the attack passed off, and with it the vomiting. On October 5, seven days after the sudden attack of pain, there was a considerable discharge of blood from the uterus, containing shreds of decidua-like membrane. This continuing, the following day, after consultation with Dr. Chambers, I dilated the cervix with Hegar's dilators, and curetted away a great quantity of decidua. The sound passed 4^ inches. Haemorrhage followed this ])rocedure so profusely, that it could only be controlled by injecting a solution of perchloiide of iron (1 in 20). Collapse was marked, and for twenty hours the pulse kept at 160. It gradually resiimed its previous rate of 120, the temperature ranging about 101°. There was no more bleeding after this, but the general condition remained unchanged. There was much sweating, and progressive loss of flesh, but no pain nor shivering. The tumour gradually increased in size, and on October 27 was noted to have extended to two inches above the umbilicus, and to have crossed the middle line for a like distance. On November 2, ether was administered by Dr. Jenkins, and assisted by Dr. Chambers, I performed abdominal section. The parietes were highly vascular, and, to the right of the middle line, the cyst was TWO CASES OF EXTRA-UTERINE PREGNANCY. 665 found to be uuivei'sally adherent ; to the left, it was free. With the aspirator I drew off about two pints of dai'k grumons-looking fluid, which subsequent examination showed to have a specific gravity of IOl'O, and to be highly albuminous. The microscope showed a few red corpuscles ; others, which were similar to white or pus cells, and much granular matter. The cyst was incised, and its margins stitched to the edges of the abdominal wound. On exploring the interior with the linger, a body the size of a small hen's egg was found engrafted on the lower wall ; it fluctuated, and when incised appeared to contain similar fluid to that in the cyst. A drainage tube was inserted, and the wound closed in the usual manner. Recovery was very slow, the patient being confined to her bed for two months. Sanious pus and necrosed tissue continued to discharge from the cyst, so that I was unable to remove the tube until the end of the third month. At the present time she is in good health, and menstruates normally. It will be noticed, that no foetus w'as found, and therefore it may be contended that this was not an instance of extra-uterine pregnancy at all ; if, however, the case be viewed as a whole, I think it will be admitted tl)at tlie diagnosis was warranted by the facts. I base my opinion, more particularly, on the detection by the patient — who was very spare — of a small lump ; on her feeling so, that she was led to suspect pregnancy ; on the sudden attack of agonising pain, followed immediately by collajtse, and later on by peritonitis, with discharge of blood and shreds of membrane ; and on the enlargement of the uterus, with formation of decidua. The second case (Mrs. H.), I saw in consultation with Dr. Power, on January 11th, 1888. She gave the following history :— yEt. 28; married nine years, two children (last seven years ago), no miscarriages, menstruation had been regular and health good up to eight months before ; she then missed a period, and thought herself pregnant ; the flow, however, appeared a week later, and lasted two weeks. It was regular every month after this until the last two months, during which there was again a break, while for the last two weeks there had been a profuse discharge. From the time the menses flrst ceased, she was troubled with pains in the lower abdomen and occasional vomiting, which culminated during a period, four months before I first saw her, in an attack of agonising pain, followed by collapse. Her usual medical attendant was hastily summoned, and administered morphine hypodermic-ally. Repeated doses in the course of twenty-four hours subdued the first violence of the pain; but sijice then, she had been more or less confined to bed. About three months ago, she noticed " pieces of flesh" coming away with the menstrual flow ; milk also appeared in the breasts, and she felt what appeared to be movements. She con- sulted one of the leading surgeons in Sydney, who told her she was pregnant, and this assurance satisfied her for a time. Becoming alarmed however at her increasing weakness, with occasional shivers and profuse night sweats, she called in Dr. Power, who asked me to see the case. We found her much emaciated. Temperature 101°, pulse 112. Tongue dry. Abdomen hard, distended, and moderately tender. Id the hypochondriac and right inguinal regions, extending nearly to the umbilicus, could be distinguished a tense cyst. Per vaginam, the cervix had somewliat the soft feel of pregnancy, the uterus 666 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA, was firmly fixed, and the vaginal vault hard and tender ; the sound passed to the left three and a quarter inches. Taking these physical signs in conjunction with the foregoing history, there was little difficulty in arriving at the conclusion, that we had to deal with a case of ectopic gestation. The patient's means not allowing of home treat- ment, she was admitted into the Sydney Hospital, and on January 19 I opened the abdomen in the middle line. On raising the omentum, which was extremely vascular, the cyst, which had been felt thi'ough the parietes, was found to be the right broad ligament distended with fluid, and containing in addition some hard body. It was, to a large extent, adherent to surrounding parts, and over its surface ramified several enormous vessels. With the aspirator, I drew off" sufficient stinking pus to relieve the tension ; I then incised, and extracted, in j)ieces, a putrid foetus of about the fifth month. Every precaution was taken to prevent contamination of the peritoneum, and all pus having been removed from the cyst with the syringe, its edges were stitched in the abdominal wound. The placenta was left undistui'bed. A large drainage-tube was inserted, and the cyst syringed out with warm carbolic lotion three times daily. From the third day, small pieces of placenta, loosened by the syringing, were removed by forceps; and on the twelfth day, the entire mass was found to have separated, and was removed in the same way. The foetid discharge rapidly diminished after this, but it was not until the thirtieth day that I was able to take away the drainage-tube. The temperature, winch had ranged from 100° to 103° before operation, fell to 99° afterwards, and never again exceeded 101° ; it did not, however, become perfectly normal until the twentieth day. On the thirty-seventh day, the patient was allowed up, and at the present time is in perfect health. In discussing this subject generally, it would be well if attention were directed to some of the points most in dispute. What, for instance, is the opinion of members on the doctrine of Lawson Tait, that all extra- uterine pregnancies are at first tubal 1 For my own part, a close study of the evidence has failed to convince me of its truth, and I agree with Harris that such a theory is refuted by those cases in which the placenta has been found attached to a remote part of the abdominal cavity. Again, do cases of tubal pregnancy frequently, or ever, come under the notice of the surgeon prior to rupture ? and, if they do, what are the diagncstic points upon which reliance should be placed'? and what treatment should be adopted? In America, the diagnosis of such a condition appears to be by no nieans infrequent ; and as regards treatment, the profession there are j)retty equally divided into those who advocate abdominal section, and those who rely on electricity. I give in my adhesion to the former, for I cannot conceive how a mode of treatment can long continue to " hold the field," which may prove immediately fatal by causing rupture of the sac, and which, although it can kill the embryo, yet leaves it as a sleeping danger, liable at any time to light up fatal inflammation. Finally, we come to the most difficult question of all. What is to be done in cases of advanced ectopic gestation 1 Are we to operate at once, or wait until tlie child be viable ? or until after pseudo-labour and cessation of circulation in the placenta 1 And when we do operate, how should the placenta be dealt with 1 Four times it has been removed CONDITIONS AVARRANTING REMOVAL OF THE OVARIES AND TUBES. G67 with success at the time of operation, viz., by Martin, Lazyarewitch^ Breisky, and Eastman — the two latter operators extirpating, in addition, the entire sac. In this ex-section of one or both, as may be possible, lies, I believe, our best hope of coping successfully with this great ditHculty. While I shall be glad to hear any criticisms of my own two cases, I think it of much greater importance to endeavour to have recorded, for the benefit of womankind, the matured opinions of Australian surgeons upon the unsolved problems connected with this subject. CONDITIONS WARRANTING REMOVAL OF THE OVARIES AND TUBES. By W. Balls-Headlev, M.A., M.D. Cantab., F.E.C.P. Lond. Lecturer on Obstetrics and the Diseases of Women at the University of Melbourne. Hon. Physician to the Women's Hospital. President of the Medical Society of Victoria. Fellow of the Obstetrical and Gynaecological Societies of London, d-c, &c. When abdominal section was an operation which involved serious risk to life from imperfection of details, it was natural it should be delayed till the risk to life was immediately palpable and great; and some vague rule existed that ovariotomy was justifiable, when tlie patient could no longer walk half a mile. Now, more happily placed by experience and a comparative immunity from danger, the period of operative interference may be regulated and defined more in accordance with science by our experience of the comparative dangers of removal, and of non-interference or delay. The diseased structures may be conveniently divided into :— (1) Progressive ovarian cystic degeneration, and (2) Other abnormal conditions of the ovaries and Fallo[)ian tubes. Progressive ovarian cystic degeneration. — In regard to the first, I would at once advance the necessity of immediate operation on the discovery of the tumour, for the following reasons : — (1) That the opei'ation in the earlier time is almost without danger, (2) That the nature of the disease being progressive, removal will be ultimately compulsory. (3) That complications in the course of its development are liable to occur, Avhich greatly enhance the subsequent risk to life, whether uninterfered with, or in the operation. That the operation in the earlier time may be almost without danger, in the hands of the lapai'otomist of the present date, will probal^ly be accepted as not requiring proof. The removal of a practically unilocular cyst, without complication, is the easiest form of peritoneal removal "668 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. that can be found, and reports of sucli successful cases by general practitioners, all over the country, are constantly recorded. The incision may be but of two or three inches in length; the abdominal cavity need not be touched ; no fluid need enter its cavity ; and it would appear that, with the most ordinary abdominal knowledge, there is nothing to cause death. But if in the earlier stages there be difficulties, there can be little doubt that later they will have increased, and one cannot suppose that they can be materially diminished by the progress of the ■disease. Nor is there a reasonable expectation but that the operation will ultimately be recpdred. During the interval between the recognition of the tumour and tlie time when the condition of the patient necessitates its removal, the mind and health sufi"er, and danger is incurred of complications presently to be mentioned. It is true that such term may be long, yet it is rare that operation is not ultimately necessary. In a case reported in the Lancet of November 1887, I tapped a cyst ■occupying the pelvis in 1881, and removed a multilocular cyst in 1886. During the interval, the patient had been constantly in the hands of doctors, and was finally a complete invalid. By such delay, a period of health was lost. The longest interval with which I am acquainted is that of Mrs. L., fet. 73, who had, forty-four years previously, noticed a tumour in the right abdomen, and for the last two months had been incapacitated by pain in it. A dermoid cyst, tmiversally adherent, was successfully removed. Thus, in a stationary tumour, as to size, even where degeneration had, or perhaps in consequence of its having proceeded to its utmost limit, removal was preferred by an old lady of 73, rather than suff'er the pain induced by its presence. The effects of pressure on the abdominal organs and vessels require to be only mentioned. This is not comparable to that of pregnancy, which, however occasionally injurious, is but temporary. The capacity for adaptation is frequently strongly exemplified, and we may wonder at the apparently small inconvenience ; yet such pressure is often evidenced by tlie partial obstruction of the rectum by a pelvic tumour, producing constipation, flatulence, and indigestion, which promote chronic blood jwisoning by absorption of ftecal matters, evidenced by the muddy complexion and de[)ressed spirits. There is the annoyance of frequent or painful micturition, by pressure on the bladder ; perhaps disease of the kidneys with albuminuria, by direct pressure, or more probably by partial obstruction of the ureters ; congestion or disease of the liver, by pressure on it, or compression of the biliary duct ; irritability of the heart, by its displacement upwards ; oedema of the legs, by partial obstruction of the inferior vena cava or great veins ; as well as ascites, from some one of these conditions. Some one or more of these results of pressure are witnessed in most cases of tumour of any size according to its site. A complication which much creates new conditions of danger, is the peritonitis resulting in adhesions, whether induced by injury, or by^ inflanmiation extending from within the tumour, or by rupture of a cyst into the abdominal cavity. In the case of a Mrs. M., from whom I removed a large dermoid tumour, the intestine was thus firmly adherent to the abdominal wall, and compressed between it and the tumour, producing alternating obstruction and diarrhoea ; for its COXDITIONS WARRANTING REMOVAL OF THE OVARIES AND TUBES. 609 removal, an opening had to be made througli the omentum. In tlie case of Mrs. L., the okl hxdy of seventy-three, similarly with a dermoid tumour, the intestines were closely attached, while the sac was calcareous and in sections, resembling the hydrocephalic skull of a newly-born child. All her arteries were also densely atheromatous. This case was also complicated by a fibroid of the uterus, which occupied the whole pelvis. In a multilocular case of Dr. Hewlett's, in which there was great pain and high alternating temperatures, some small internal cysts of the tumour contained pus, others being of various qualities, and there were most firm adhesions everywhere, especially to the rectum and deep in the pelvis ; an injury was done to the intestine, and she died. IVIrs. H. had a small ovarian tumour, wldch burst into the peritoneal cavity without apparent cause, and death ensued from acute pei'itonitis. In a case on which I lately operated, the sac had dissected its way under the broad ligament. She took a long coach journey, and a sudden and large venous hfemorrhage occurred into the sac, so that the tumour greatly and rapidly enlarged, and her temperature rose ; so great Avas the pain, that she could neither lie nor sleej:). At the operation, the sac was found partially mortified from pressure, the fluid being nearly black and very ofiensive ; being aspirated, the gas did not enter the peritoneal cavity ; the condition simulated that of a twisted pedicle. The sac had to be enucleated from the peritoneal membrane ; and, opei-atively, there appeared no reason why immediate recovery should not ensue, but she sank from the effects of the absorbed septicaemia. It is unnecessary to multiply such cases. It is certain that the longer the existence of the tumour, the greater the probability of peritonitic adhesions and of consequent difficulty and danger in the operation, of mortification of the sac or its contents, of suppuration, or of spontaneous rupture and fatal peritonitis. One of the most frequent causes of immediate danger is the twisting of the pedicle by rotation of the tumour. The size of the tumour, within moderate limits, does not appear to materially affect such rotation, which is rather influenced by its form, and the degree to which it may be steadied by its occupation of the pelvis. The almost invariable result of such rotation is peritonitis, from obstruction to the return of the venous blood ; but the death of the sac will depend on the completeness of such obstruction. In a highly unsatisfactory case, which I had some years ago, a very stout woman, with fat abdominal walls, had a deep lacera- tion of the cervix uteri, with such eversion and granulations as to simulate malignant disease. I performed Emmet's operation on the cervix ; but immediately afterwards her temperature became high, and she got peritonitis, without apparent cause so far as the cervix was concerned. She presently died, and at the post-mortem, an ovarian tumour of the left side, of the size of the head of a six months' fostus, was found to have twisted its pedicle, which induced the fatal inflam- mation. The whole attention had been centred on the condition of the uterus, and the examination of the abdomen of this thick-walled woman had been incomplete prior to 0})eration, and impossible from distension after the advent of inflammation. Probably the rotation of the tumour had been effected by the laxation of the parietes imder the anaesthetic, in conjunction with her being placed in Sims' position. 670 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. A very severe case of this rotation occurred in a patient of Dr. Scblesinger's, of St. Kilda, who had been putting up curtains. She had not suspected a tumour, having had many children. Her peritonitis induced a temperatui'e of 105°. Having thus diagnosed, I removed the blackened gangrenous tumour, and she made an excellent recovery. It is probable that the occurrence of pregnancy may tend to increase the probability of such rotation, by the enlarging uterus raising the ovarian tumour out of the pelvis. A patient of Dr. Barker's, of South Melbourne, the mother of three children, got an acute peritonitis, her catamenia having ceased for three months. On its partial subsidence, a tumour was found. On opening the abdomen, the dusky tumour was found full of dark blood, and the constriction of the veins was so great, that an extensive venous rupture was found on the right broad ligament with effusion of blood into the peritoneum, which conditions induced the inflammation. The patient afterwards miscarried, from the healed intestinal adhesions preventing the rise of the ])regnant uterus, but she made a perfect recovery. This case was fully reported in the Lancet of November 1887. Yet the constrictions need not be so complete. In the case of a tumour of the size of a child's head at term, the temperatures were erratic, and, it being some eight years ago, I awaited for some weeks their subsidence before operating. This not occurring, the abdomen was opened and the tumour removed ; but a general phlebitis had spread from the twisted compressed ovarian veins to those of the bladder and pelvis, to which she finally succumbed. In another case, under the care of Dr. Brownless, the tumour of the size of a child's head had become so much twisted that she was seriously ill with peritonitis, and Dr. Brownless tapped the tumour. The patient continued ill, and was unable to perform her domestic duties ; on operation, I found a dirty brown cyst loosely adherent, but not so unnourished as to be actually gangrenous, yet sufficiently so to injure the system by absorption ; but her recovery was complete. These cases are sufficient to show that, whether in small or large tumours, or in combination with pregnancy, rotation of the tumour with dangerous constriction of the veins is liable to occur, whereby greater danger is incurred. That malignant disease is liable to be induced by persistent irritation, is established ; and the principle applies not less in the case of ovarian tumours than of other morbid conditions. In November last, I operated on a woman in whom an ovarian tumour of the right side had acquired extensive adhesions to the intestines, and had spread itself deeply under the broad ligament. A second tumour of the left side filled the pelvis, and from its upper edge sprouted epithelial growths, which were in a stage of rapid progress. The cases are not infrequent in which such cancer affects the mesentery and intestines, having apparently originated from the external surface of the ovarian sac ; such additional diseased growths form a further reason for an early removal of such a source of irritation. I have thought it well to adduce so many fatal cases, to show how serious simple cases are made by delay. For the several consequences mentioned above, I think it cannot but be our duty to .strongly recommend the removal of progressive ovarian cystic tumours at the earliest date at which we become aware that CONDITIONS WARRANTING REMOVAL OF THE OVARIES AND TUBES. 671 they have risen out of the pelvis, or produce such pressure there as to require that it be reduced. (2) Of the abnormal conditions of the ovaries and Fallopian tubes. — From the point of view of the desirability of removal, I would first consider the simplest, and advance towards the more serious. Thus, certainly the simplest condition is the misplacement of one or both ovaries without adhesions, which so frequently occurs in the parous woman, as the result of lacerated cervix, with its so common sequelcB of sub-involution, retroflexion with dragging on the broad ligaments, and the falling back of an ovary, tube, or of both. Thus the ovary may become pressed between the fundus uteri and the sacrum ; and on replacement, it may find its way to compression by a pessary. Such conditions as this may be met by various modes of treatment, and I have not seen the case which in my opinion necessitated removal. As a further com])lication in these cases, pelvic peritonitis may bind down such misplaced ovary, when the case becomes identical in its condition with that of adherent ovary, which so frequently occurs in the nulliparous, next to be considered. By far the greater number of cases of aSected ovary or tube, or both, have their origin in the virgin or nullipara, though similar conditions occur in tliose who have been pregnant. The friends of a suffering girl find it necessary to take medical advice, and an examination is made. The simplest condition found, leading in the direction of enlarged ovary or tube, is perhaps a congested os, with evei-sion of cervical mucous membrane, forming the state called "granular"; and there is endo- metritis. Many of these cases simulate a laceration of the cervix, so large appears the opening, caused, however, by the pressure of the constant protrusion. A farther step may be, that the greater weight of the heavy inflamed uterus has depressed the organ in the pelvis ; and, its axes being followed, retroflexion has resulted ; or it may be anteflexion. The ovai-ies and tubes have followed such retroflexion, and may be felt misj)laced, tender, and perhaps enlarged. In comparatively few cases thus advanced can the uterus be replaced and retained in position, pelvic peritonitis having bound down the parts. In such peritonitis, the ovaries and tubes participate. It appears to me, that the above states are oinginally caused by an inflammatory state of the lining membrane of the uterus, whether induced by a contracted outer or inner os ; by pressure on the canal, from anteflexion ; by deficient development ; by flexion from accident ; by unsatisfied desire ; by excessive develoj)ment and exudation of utei'ine mucous membrane, as in fibrinous dysmenorrhcea ; or by the inflamma- tion of gonorrhoea : that if such inflammatory thickening should exist near the uterine openings of the Fallopian tubes, and be sufficient to hinder or prevent escape of their secretions — a condition which a similar progressive inflammation of the tissues of the tubes, with compression of their proximal ends, serves to confirm — a bar to the escape of secretion is formed, which secretion, now rendered muco-purulent by the inflammatory action, ])asses oiit at the fimbriated extremities, whereby a pelvic peritonitis is caused : that thus the tubes become bound down, and unable to accommodate themselves to the surface of the ovaries : that 672 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. the ovaries probably participate in such peritonitis : that the Graafian follicles, as they develop in due course, can with difficulty burst through the organised peritonitic lymph : that their fluid thus accumulates, and compresses the ovarian tissue, producing pain, local inflammation, and gi'adual absorption of ovarian tissue : and that thus such ovaries are finally liable to become bags divided into a few small cysts, which cysts have no relation to the true progressive ovarian tumour ; or, if such follicles can burst, or the Fallopian distal extremities ai-e free, and can continue to dischai-ge their contents into the peritoneal cavity, successive attacks of more or less local peritonitis with progressive adhesions occur ; but if the fimbriated extremities be occluded as well as the uterine, accumulations in the tubes occur, forming muco-, hydro-, or pyo-salpinx, some relief to which may occasionally be afforded under varying conditions by escape of fluid into the uterine cavity. I can adduce cases in every stage of the above-mentioned conditions, from those of the endometritis with extensive granulations, gradually advancing, as noted in the course of years, into the enlargement of the tube or ovary with frequent intermediate pain or invalidism, up to a case now under my care, in which there is extensive granular tissue at the OS ; the uterus is enlarged and inflamed ; the left tube and ovary are enlarged ; there is general peritonitis and pelvic cellulitis ; and the temperatures vary from 99° to 103°. From the consideration of the cause and progress of this class of cases, must be derived our opinion as to the desirability or otherwise of removing the ovaries and tubes ; and this will much depend on the period at which we see the patient. Early, nothing may be found but evidence of the inflammation of the lining membrane, with or without some thickening of the tube or ovary ; and undoubtedly, treatment adapted to the state of the uterus may be sufficient to restrain the progress of the disease, at any rate for a considerable time ; yet in several cases which I have watched for years, though the os and cervix appeared to have been rendered quite normal, an attack of pelvic peritonitis would occasionally occur, and a tube or ovary, at times scarcely felt, would enlarge — at last to subside, and the whole genital organs to become atrophic, or advance into permanently diseased bodies. In view of the progressive character of the natural histoiy of the disease ; of the formation of the adhesions, which, by lapse of time, become exceedingly dense ; of the liability of fluid, mucus, pus, or cystic, whether of the ovary or tube, escaping into the cavity of the peritoneum, the bowel, or bladder ; any of which complications much increase the danger of operation, I think it may be rightly determined to remove the diseased organs as soon as it is found that the woman can no longer satisfactorily [jerform the duties of her life ; or that frequent attacks of local peritonitis occur ; or when, from one such peritonitis of consider- able duration, it may be inferred that the condition is one of progressive disease ; and that, in the presence of these conditions, the sooner the operation is performed, the less the danger and the greater the expecta- tion of complete recovery. Of the numerous complications which may occur, pregnancy may first be mentioned. In a fatal case of septicaemia after miscarriage, the pregnancy had occurred by the healthy tube, the other being a bag of pus. Had an operation successfully removed this tube and ovary, it CONDITIONS WARRANTING REMOVAL OF THE OVARIES AND TUBES. G73 may have been that the pregnancy would have continued ; certainly, had the conditions been recognised, the operation should have been performed. In view of the frequency of both tubes or ovaries being affected, the condition of only one of which may have been ascertained even in the case of considerable enlargements, as well as from other considerations and difficulties, it is evident that it is unsafe to trust to minor operations as aspiration, though several aspirated cases have terminated temporarily successfully enough ; yet, in all but one, the parts have continued to give trouble, which would not have been the case had they been successfully removed. Tlie dangers of delay were exemplified in a case of many years' standing, in whom at length blood poisoning symptoms were acute, and it was evident life could not long continue. On operation, there was an exceedingly foetid abscess of the left tube, embedded in the lymph of a chronic cellulitis and peritonitis, while the mesentery and omentum were closely adherent in the right pelvic cavity, with general matting and many points of gangrene. All was cleared away as far as possible, but the patient sank. No doubt in gonorrhceal extension, the disease of the tubes and ovaries is usually double. In a case I lately read, among others, before the Medical Society of Victoi'ia, a considerable abscess had formed in each ovary, but the left was so large as to push the uterus to the right, and the right abscess was not perceptible before operation on this account, and through the peritonitic distension. She recovered. While, then, in the more chronic cases with no immediate danger we may calmly argue out the desirability of removal, such latitude is not justifiable in the more serious cases of blood poisoning temperatures, where, with some suppurative condition of tubes or ovaries, there may be peritonitis, and, indeed, usually is. Here the main point is, not to delay too long ; again, the earlier the operation in this condition, the greater the success. Yet of complications, there may well be great hesitation in those cases in which an undesirable delay has permitted rupture into the intestines. Such abscesses fill and empty, and thus alternate till the patient may be worn out, or succumb in an acute attack of peritonitis ; but I have known some cases, in which finally the sac appeared to have closed or become quiescent. Yet this is not the usual result ; and such has been the frequent discomfort and danger, that regret at neglect of the early operation has frequently recurred. In operating with such a ti*act, it is to be anticipated that the adhesion will so break down as to leave a faecal fistula, the danger of which will mainly depend on the extent of cohesion by previous peritonitis. Such cases, as a general rule, are better left alone ; but they should have been removed early, and in no case aspirated, which complicates removal. And again, when pelvic cellulitis is a complication, the gravest doubts of successful removal may well be entertained. The anticipated matting of every tissue, coupled with the softening of a pelvic cellulitis, may readily permit the stripping off" of the peritoneum with underlying cellular tissue, leaving a raw cavity, instead of the mere separation of adherent surfaces of peritoneum ; and as the whole contents of the pelvis are intimately connected l)y inflammatory products, it is impossible in such an operation carefully to dissect part from part. In such cases, Ix 674 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. it is a mattei' of anxious cai'e to decide whether to hope that tlie patient will not die of her almost necessarily progressive disease, or to attempt removal ; and again the rule holds good that, if it has to be done, the earlier the better, before the feebleness of the patient shuts out all hope. The conclusions thus arrived at are : — (1) That in the earlier or more chronic stages, the rule may be, that removal is desirable when a woman can no longer satisfactorily perform the duties of her life ; or when attacks of local peritonitis are frequent, or where such an attack is of considerable duration. (2) That in the stages of blood poisoning from absorption or presence of pus, without pelvic cellulitis or previous rupture into the intestine, removal is essential. (3) That in the late conditions with pelvic cellulitis, or rupture into the intestine, such operation should only be entered upon as an alterna- tive from the anticipation of eventual death, but be performed even then as early as such fatal natural conclusion seems positive. TWISTING OF PEDICLE IN OVARIA.N TUMOURS. By Wm. Gardner, M.D., C.M. Glas. Lecturer on Surgery, Adelaide University. Senior Surgeon to Adelaide Hospital. The subject of this short paper is of great interest to all gynaecologists and operating surgeons generally, both on account of the difficulties involved in the diagnosis, and also because many important points in treatment yet remain to be definitely answered. Personally, 1 had not given any attention to this condition until the occurrence of two cases in my practice, within three months, led me to study the literature of the subject. Appended to this paper are short notes of the cases to which I refer, and they are instructive because they furnish examples of successful and unsuccessful terminations. In Case No. 1, it is evident that rotation of the cyst took place with twisting of the pedicle, followed by extravasation of blood into the cyst and peritonitis, with the formation of adhesions as a conservative process, and designed to assist in carrying blood to the tumour, the supply of which must have been to a large extent cut oflf by the rotation of the pedicle. The patient was not known at the onset of the symptoms to be the bearer of an ovarian cyst, and the appearance of the pedicle, when cut, was strongly suggestive of what one would regard in other parts as gangrene. Case No. 2 is an example of a patient not known to be suffering from ovarian tumour, but in whose case rotation occurred during pregnancy, followed by extravasation of blood into the cyst, and then finally rupture into the abdominal cavity and peritonitis. In both cases the symptoms, as interpreted by the medical attendants, pointed to obstruction of the bowels; but in the first case, the discovery and aspiration of a tumour, under ether, led to a correct diagnosis of ovarian cyst. In the second case, however, no diagnosis was arrived at, • CO C\J i. -- 1 -i--- --.L -■ 1 r ■■■ CM . CM I T i < 1 ! o " 1 2 - - 1 .- i 1 I ..- '^ i - . - 1 Li. 1 V 2 ~ < \. ^. ;- — ? £ - - - 1 ">• - ■ CD C t~. ul - -~- -' 1 im — 1X3 CC ^ 1 Z ! 1 :^ — C_3 u> ui 2 - • -^ - -^ "Z* CD ^ ul 2 - - — ~_,_ ,>= — -2 C5 2 < " --C ,^^»^ 1 - — CO CNJ w -- < > r" --- 3 O £ - ui ■- - -v.. r' — 3 ! — o Ul 2 --- --^^ Y a. 00 en 5£ -- < -^ - - - CO O c o ^ 1^ -- - -\. " ^ Ul ''''^-~- -— . S ^^ — ■ >• CD Ul 2 '^ ~- >- -- 1 J. . - --- LO Ul ---- --- --- <:.^ ^ f — — vi- s --- V ' — nn UJ --- _.< l ' ' — -- i c r-J IfAi •^ ., - - — C/T X ''» 5 1— UJ •t^ [r>* i -- 1 -- - - " - 1 CD Ul Z y - r - 1 _-_ --- — _ 05 Ui '■^ - - >- \ \ ^ ul Z -V rrT jk 1 ■■ ... --- S --- u 7/yr. sa'o ^ ... --- ul i [ 1 2 1 1 1 i 1 — =■ 'O S S e i 2 « s; CT CT TWISTING OF PEDICLE IX OVARIAN TUMOURS. 675 as tlie tumour was small, and the patient was four months advanced in pregnancy. It is noteworthy, that the direction of the twist in the second case, which was a right ovarian cyst, was from ri^ht to left; and in the former, it was from left to right, the left ovary being involved in til is case. The treatment adopted in tlie first case was to wait until the acute symj)toiiis had passed off, and then perform laparotomy, which fortunately was successful. In the second case, the })roblem presented to us was a much easier one, as diagnosis, after rupture of an ovarian cyst not known to be present, is impossible. We came to a decision to perform laparotomy for some unknown abdominal condition, as the patient was rapidly becoming worse, and it was a last, thougli not very promising, chance. The result of the laparotomy was failure, and al)ortion took place ; but, as cure could not have taken place by nature's \inaided efforts, the operation was in my opinion fully justified, although the duration of the illness (a week) militated against success. In the International Journal of the Medical Sciences, October 188S, Mr. Thornton, in an excellent paper from which I quote freely, states that out of 600 cases of ovariotomy, fifty-seven had twisted pedicles, i.e., more than 9 ]ier cent. ; and seven of these had ruptured at the date of operation, i.e., 14 per cent., or about 1 per cent, of the whole number of cases. Of the fifty-seven cases, four died after ovariotomy; and of the seven cases of ruptured cyst, one only died. History. — Thornton states that Patruben, in 1855, recorded a case of rapidly fatal intra-cystic htemorrhage, from rotation of an ovarian tumour. Rokitansky, in 18-41, first drew attention to the subject in his "Handbook of Pathological Anatomy;" and in 1865, the same author published a paper on " Strangulation of Ovarian Tumours by Rotation." In making autopsies in fifty-eight cases of deaths from ovarian disease, he found twisted pedicles in eight cases, Spencer Wells, at page 61 of his work on " Ovarian and Uterine Tumours," says that he met with this condition in from eighteen to twenty cases, and in two of the cases it caused death before operation. Wiltshire, in the " Transactions of the Pathological Society of London, 1868," has published notes of a case in which he successfully removed a strangulated ovarian tumour during ihe acute stage of axial rotation. Lawson Tait and Alban Doran have published a number of cases, and have written in their resjjective works on " Diseases of the Ovaries " on the subject, and to these works we shall later on refei". Scattered through the medical literature of the last few years are a number of single cases, illustrating more or less completely the various interesting phenomena accompanying the condition of twisted pedicle. Results of the Accident on the Tumour and Surrounding Parts. Spencer Wells says that, after rotation has occurred, " the great veins are compressed, and blood continues to pour in by the arteries. Con- gestion, exudation of serum, extravasation of blood into the cysts, and nipture follow in rapid succession; antl unless timely relief is afforded by ovariotomy, the patient soon sinks. If the rotations are so complete and enduring as to strangulate the arteries of the pedicle, gangrene is Ix 2 676 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. inevitable. In other instances, the constriction of the vessels by the change of ]iosition is so moderate, that the tumour itself is not much affected, but it remains stationary, and contracts adhesions to some of the viscera, and cannot be replaced." Eokitansky mentions one case in which a strong cord-like band so ligatured the sigmoid flexure of the bowel, that the slightest change of position rendered it impermeable. The bowel has also got so entangled with a long pedicle, during rotation, as to become strangulated. Even after new vascular alliances have been formed between the rotated tumour and the omentum and viscera, the pedicle has by some means, either tension or pressure, been divided. In such a state of transplanta- tion, the tumour has drawn its nutriment through the newly-formed vessels of the plastic adhesions, and its ])arasitic existence has not been much less vigorous than before. Thornton expresses his views as to the results of rotation in the following passage : — " First we have interference with the circulation ; the firm arteries, resisting pressure, continue to pump in blood, which the yielding veins cannot return quickly enough, so that congestion with exudation of serum, rupture of vessels, and extravasation of blood and rapid enlargement of the cyst, result. These ]H'ocesses are accom- panied by acute pain, chiefly referred to the pedicle, and due to the pressure to which its nerves are subjected, but also in extreme cases extending over the whole surface of the tumour ; also by reflex symp- toms, such as vomiting and collapse, and l)y fainting and pallor, the result of internal hemorrhage. The strong fibrous covering of the tumour prevents ru]iture of the external vessels, and in the majority of cases confines the effused blood ; but if, as sometimes happens, previous inflammatory changes in the cyst-wall have caused blocking of vessels and deficient nutrition of portion of its substance, these, being soft and lacerable, give way, and the mixture of ovarian fluid, serum, blood, and clot, is poured into the peritoneum. This accident is, as we have seen, often speedily fatal ; but in many cases, the pedicle vessels being closed by clot, the haemorrhage ceases ; the effused matters, after causing more or less peritonitis and fusion of parts, are absorbed, and the patient slowly recovers, till the rent in the cyst heals, and the adhesions affording a new blood-supply, the tumour starts growing again." Theories as to Causation. In 1880, Lawson Tait read a paper before the Obstetrical Society founded on three cases of twisted pedicle in right-sided tumours, and advanced the theory that the solid wedge of ft^ces passing down the rectum was the cause of the rotation. This may be one of the causes, but cannot be the only one, as Thornton's cases show an almost equal number of twisted pedicles in right and left-sided tumours, and this theory would not explain the latter. Thornton, in a paper published in 1877, suggested " that the peristaltic action of the intestines may start the process, and that the twist once started, the pulsations through the cord tlius formed would tend to increase it." He also said, "If the case is complicated with pregnancy, the foetal movements may play an important part." Doran, in describing a post-mortem on a case of ovarian tumour complicated with cancer of the rectum, says : — " A little artificial TWISTING OF PEDICLE IN OVARIAN TUMOURS. G77 ilistension of the intestine caused it to press against the tumour so as to push its left side backward, stretching and twisting the pedicle." Ther'e was no twist in the pedicle, but its vessels were blocked with old clot, and he considered it probable that the loading ot the rectum, caused by the cancerous stricture, may have caused enough twist to set u]) clotting in the vessels. Doran's opinion is that " as a rule the twisting of a pedicle is to be explained by the simple doctrine that the tumour, pressed u]>on by the viscera and even the costal cartilages above, and by the i)elvic structures below, but comparatively free laterally and anteriorly, rotates on its own axis every time that the })atient, after walking or lying on her back, 'turns round and rests on her side.'" There is a general consensus of opinion, that pregnancy predisposes to rotation in ovarian tumours ; foui'teen out of Thornton's fifty-seven cases were thus associated. Tapping has also been suggested as a possible cause of rotation, and in several recorded cases it certainly preceded the accident by a few days. Other causes too numerous to mention, and unfortunately, also, too insusceptible of proof, have been suggested. They are mostly of the 2x>st hoc, propter hoc kind. Klob has suggested the alternate tilling and emptying of the bladder as a cause. Direction op the Twist. For tumours of the right side, the twist is generally from right to left, and the reverse in tumours of the left side. My two cases followed the general rule, but there are a few undoubted instances on record in which twisting in the reverse way took place. Dermoid and small tumours are .specially liable to rotate. PtEMARKS. Looking back on my experiences in ovariotomy, I feel sure that I have frequently passed by unnoticed minor degrees of rotation, but the cases now recorded are the only ones in which I have met w-ith serious pathological results. As far as my reading goes, the only contribution in Australia to the interesting subject of rotation of ovarian tumours was made by Dr. Balls-Headley, in the AvMralian Medical Journal of November ].5th, 18S0 ; and although in the discussion which followed, some of the speakers ventured to doubt whether the case was one of axial rotation, I cannot help thinking, from the reported condition of the cyst contents, and the recently-formed adhesions, that the operator ■was correct in his interpretation of the facts. Case I. Mrs. C, a;t. 38, married, residing in Adelaide. Was delivered of her last child eighteen months ago, and since has complained of i)ain in the left ovarian region, and the last few ))eriods have been profuse for tlie first and second days, and then stopped suddeidy. She was attended four months ago for constijiation and pain in the left iliac region, supposed to be due to colic, and relieved by enemata. Present illness began on the morning of August 16, 1888, with acute pain in the left iliac and lumbar regions, accompanied with nausea, 678 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. vomiting, and constipation. Patient stated that the period had stopped suddenly on the 14th. Temperature found to be normal ; pulse 84, full and regular, features pinched, abdomen excessively tender in the above- named regions, with an ill-defined sense of fulness. Ordered hot fomentations, and a mixture containing morphia. August 18. — Pain much more severe; vomiting continues; bowels still unrelieved in spite of enemata ; pulse 84, temperature 99*8°. August 19.- — Slight improvement; sickness has ceased; bowels not yet opened ; pulse and temperature as before. 11 p.m. — Patient fainted on getting out of bed to pass ui-ine, and remained unconscious for half an hour. Takes nourishment badly. Rectum examined and found normal. Vaginal examination shows no fulness. Uterus not fixed ; painful on pressure. Abdomen much fuller on the lower left side, with severe pain ; no sleep. August 20, 8 a.m. — Much worse this morning. Face dusky, features pinched. Pulse 120, feeble, regular. Breathing quick and shallow. Ko sickness, and bowels have not acted. Tongue moist, but furred. Abdomen still more swollen, and tender in left iliac and lumbar regions. 11 a.m. — Seen by Dr. Gardner in consultation with Dr. Marten, but abdominal tenderness Avas so great that palpation could not be borne. It was decided to try if the swelling was due to ftecal accumulation by passing a long rectal tube, and administering an oil and gruel enema. Flatus passed, but no motion ; Jq gr. of stvychnife sulj^h. was given hypodermically every four hours. 6.15 p.m. — Pulse 120, feeble; no sickness, and no action of bowels. Tongue moist, but furred. As there was no improvement, it was determined to place the patient under the influence of ether. The abdomen was thoroughly examined, and an elastic and movable swelling was detected in the left lumbar and iliac region, extending high up and well to the left of the mid-line. Vaginal and rectal examination revealed nothing abnormal. Temperature 102°. August 21. — Patient was again placed under ether, and the tumour aspirated by Dr. Marten, and thirty ounces of red, glairy fluid removed. Tlie operation gave great relief. Under the microscope were seen numerous red and white blood-corpuscles, and some variable sized oily- looking rounded masses. The fluid was sticky, and highly albuminous. Ko Drysdale corpuscles found. 6 p.m. — No action of bowels. Ordered calomel gr. iv., immediately, to be followed by ^j hst. sennje co. if required. Temperature 99'8° ; pulse 116. Pain and fulness in the left iliac and lumbar regions have almost disappeared. Retention of urine relieved by catheter. August 22. — Seen with Dr. Gardner. Swelling can still be detected, but is not tender, and has a well-defined rounded liorder. Septemljer 5.— Bowels have acted freely, and the patient continues to make satisfactory progress as regards her general health, and there is no increase in the size of the tumour. Temperature varies during each day from 99' to 100°. September 24. — Patient is in e.xcellent spirits, but has wasted slightly and complains of pain in the left ovarian region, increased by movement. Tongue clean ; appetite fair. The abdomen is iri'egularly distended and ])rominent, especially over the lower left half where there is increased resistance, dulness on percussion, and marked tenderness. No dulness in either flank; measures forty-two inches at umbilicus, nine and a TWISTING OF PEDICLE IN OVARIAN TUMOURS. 679 (juarter from lower anterior superior spine to umbilicus, and eight and tliree-cpiarters between the same j)oints on the right side. September 27. — On this date, at 8.30 a.m., ovariotomy was performed by Dr. Gardner in the Private Hospital, South Terrace, to which she had been removed. Dr. Marten assisted, and Dr. Giles administered ether. An incision was made three inches long in the linea alba, and carried through an inch of fat, and the peritoneum was opened to the full extent of the external incision. There were recent adhesions in front, which were easily broken down. When the trocar was thrust into the tumour, three pints of dark thin bloody fluid escaped, and ran freely, also into the abdominal cavity by the side of the canula, as the cyst-wall was so friable, that it gave way on the slightest touch. Adhesions, which were numerous, were then dealt with, and the pedicle was found to be rotated from left to right, and the tumour required to be tui'ned completely round twice in the opposite way, to get rid of the axial rotation. The pedicle was transfixed and tied with Spencer Wells' silk, and the cyst removed. The stump was of a greenish black hue, such as we associate with gangrene in other parts, and it was deemed advisable to pare it down as closely as possible to the ligature. Tlie right ovary was found to be slightly enlarged, and was removed. The tumour was found to be almost gangrenous, owing to twisting of its pedicle, and was full of old blood-clots. Its blackish-green surface was covered with fairly recent lymph. The abdomen was then washed out with warm boracic solution, until it was thoroughly clean. A glass drainage tube was inserted into the lower angle of the wound, which was closed with silk sutures in the usual way. Patient stood the operation well, made a slow recovery, and is now perfectly Avell, except that she is much troubled with flushes. For the above notes, I am indebted to my friend. Dr. Marten, and I have also to thank him for the opportunity of seeing this very interest- ing case, and performing the operation, which resulted so successfully. Case II Mi's. C, set. 41, has had eight children, with post-partum hfemorrhage on several occasions, and after the last child was born the haemorrhage was severe, although the labour was in other respects easy. Recovery was in each case good, exce])t after the first, when she was confined to bed for eight months, owing to some unknown cause. Previous health good, except occasional bilious attacks and flatulence. Present attack began on October 26, 1888, by two sudden attacks of pain in the right iliac region, which passed off in a few minutes. She was first seen by Dr. AUwork, at 3 p.m. on October 28, when the face had an anxious expression, and the skin was slightly tinged with bile. The legs were drawn up on the abdomen; tem])erature normal, pulse 11-5, small and feeble. Pregnancy had advanced to four months. She complained of intense pain, which commenced two hours before, in the right iliac region, with intermittent spasms of agonising pain eA-ery five or six minutes, extending across the lower ]>art of the abdomen, and down the inner side of the right thigh to the knee; and during the paroxysms, the nght thigh became exquisitely tender. At the first onset of pain, passed two normal stools at short intervals, giving temporary relief. Vomiting followed immediately, the ejecta consisting at first of food and 680 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. then mucus and bile. There was extreme tenderness over the right iliac region, where an irregular, somewhat cylindrical mass could be felt extending upwards towards the liver. There was dulness on deep percussion ; no fluctuation ; swelling elastic, and exceedingly tender. There was also some tenderness over the whole abdomen, and particularly over the uterus. Examination per vaginam revealed no signs of threatening abortion. Opiates were given internally, and soothing fomentations applied to the abdomen. October 29. — Very little relief; one attack of vomiting since last night — not stercoraceous. No motion nor flatus passed, but intestines distended. Aperients and copious enemata administered, without relief, through a long rectal tube. Temperature normal; pulse 120, feeble. October 30. — The paroxysms of pain are slightly less severe. October 31. — Increasing distress, and abdomen gradually becoming more tympanitic. Opiate treatment continued. November 1. — Small amount of flatus passed once, but no motion. Patient anaesthetised with chloroform, and insufiiation performed per rectum without result. No blood passed per anum. November 2, 7 a.m. — Small amount of flatus, and also faeces and mucus passed. Dr. Gardner was telegraphed for from Adelaide, and saw the patient with me. At the consultation it was decided, as a last hope, to perform laymrotomy, and at noon the patient was placed under the influence of ether by Dr. Yeatman. Dr. Gardner having emptied the bladder, made the usual abdominal incision in thelinea alba; and on opening the peritoneum, blood and clots escaped freely. The whole hand was then passed into the abdomen in the direction of the right iliac fossa, and a mass discovered which had some loose connections to the ascending colon. These were easily separated, and tracing the tumour back, it was found to be connected by the ovarian ligament with the right horn of the uterus. It was then drawn out of the external oi)ening, and found to be an ovarian tumour, which was rotated, and had ruptured. The rotation was from right to left, and two complete rotations of it had to be made in the opi)osite direction to prepare the pedicle for ligature. The pedicle was long, and the opening in the cyst admitted several fingers. The ligatiu-e was then applied in the usual way, and the abdomen thoroughly washed out with boric acid lotion. A drainage tube was inserted, and the abdomen closed with silk sutures. 7.30 ]).m. — Patient in a semi-comatose condition. Temperature 102°; pulse 175, almost imperceptible; respirations 40, shallow. Administered stimulant enemata and ether hypodermically, but condition did not impx'ove, and the patient, after aborting, gradually sank, and died at 6 p.m. on November 3, the day after the operation. For the above notes, I am deeply indebted to Dr. Allwork, who made them at great personal inconvenience, as he was practising in a town nine miles distant from the patient's residence, and I was not able to see her after the operation— she was residing sixty-two miles out of Adelaide. Not much was to l)e expected from an operation performed so late in such a case, but we deemed it right to give the patient the remote chance; however, the "unexpected," which so frequently happens, unfortunately failed to do so in this case. PUERPERAL HYSTERECTOMY. 681 PUERPERAL HYSTERECTOMY; OR PORRO'S OPERATION BY A NEW METHOD. By H. WiDENiiAM Maunsell, M.D. Honorary Surgeon, Dunedin Hospital. Porro, of Pavia, was the first surgeon who successfully amputated the pregnant uterus in a woman — Utero-ovarian amputation as a mode of completing C;esarian section. The operation was performed twelve years ago in the Maternity Hospital of Pavia, on a woman deformed by rickets. Since then, the operation has been performed two hundred times, with a mortality of nearly fifty per cent. Instruments required. — Sti'ong scalpel, large sti'ong circular ampu- tating knife, two pairs of strong scissors, eighteen pairs of Spencer Wells' artery forceps, two strong slightly-curved needles, on handles ; curved surgical needles, suitable sutures and ligatures, specially prepared ; yaixl of strong rubber tubing, for tourniqi;et ; Tait's recent modification of Kceberle's serre-nceud, with needle for transfixing pedicle ; three large flat sponges, the bichloride antiseptic solution, and large quantities of liot water. In performing laparotomy in the median line, the incision should be lower than for simple C?esarian section, as the stump of the amputated uterus has to be brought out immediately above the pubes, as in hysterectomy. A sound should be passed into the bladder, and BAery care taken not to injure it, as it is often dragged up above the pubes in these cases. New Method of Treating the Stump. (1) The incision should be long enough to permit of the gravid uterus being taken out of the cavity of the abdomen. (2) While an assistant takes charge of the gravid uterus, place a large flat sponge, wrung out of hot water, over the bowels, to keep them warm and out of sight ; and rapidly suture up the Avound Avith strong salmon silkAvorm gut, as far as the neck of the uterus, Avhich is pressed toAvards the pubic end of the Avound by an assistant. (3) Open uterus by longitudinal incision in upper third, and remove child, leaving placenta behind. (•i) Transfix the neck of the uterus with a strong transfixion pin, and apply the rubber tourniquet below it. (5) Ligature the A-essels of the broad ligament en masse on both side.s, immediately aboA-e the pin and torniquet. (6) Pack round Avitli sponges. Make transverse incision through peritoneum coA'ering the top of the uterus, and rapidly reflect it to Avithin half an inch of the rubber tourniquet. If the peritoneum is found to be A'ery adherent to the fundus, make a circular incision all round the upper third of the uterus, and reflect it as above described. (7) Apply Kuiberle's pin and wire ecraseur to the neck of tJie deperitonised uterus. (8) Amputate the uterus Avith a large circular amputating knife, leaving a fair stump beyond the pin. 682 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. (9) Apply torsion and ligature to any bleeding points, as the assistant slowly and cautiously removes the rubber tourniquet and transfixion pin immediately above it. (10) Secure the lower end of the laparotomy wound, immediately above the stump, Avith a strong acupuncture needle. (11) Place a thin layer of iodoform wool under the reflected peritoneum, which is spread out like a saucer round the stump. Secure the edges of the reflected pei^itoneum loosely to the skin by five or six horse-hair sutures. (12) Screw up the wire clamp daily. Dress the stump night and morning ^Aith a thick layer of iodoform and absorbent wool. I have advocated this method of treating the stump in cases of hysterectomy for fibroids. As far as I know, this method of treating the stump has never been tried or suggested before. Its advantages may be summed up as follows : — • (a) The bladder and vxreters cannot be injured by the ecraseur. (b) There is no tension of the peritoneum or broad ligaments. (c) The stump cannot retract into the cavity of the peritoneum. (d) The stump is effectually shut off from the cavity of the peritoneum ; and as it shrinks and sloughs away, it is impossible for the matter to drain on to the abdominal wound, or into the cavity of the peritoneum. Godson's Classification. (1) True Porro operation — fcetus A'iable. (2) Utero-ovarian amputation performed during pregnancy, before ftetus is viable. (3) Laparotomy for removal of fo?tus from abdominal cavity, followed by amputation of ruptured uterus and ovaries. The same treatment of the stump applies with equal force to all these conditions. In puerperal hysterectomy, experience is strongly in favour of the extra-peritoneal method of treating the pedicle. According to Godson's tables, eleven died out of fifteen cases treated by intra-peritoneal methods. DISCUSSION. Dr. Jakins supplemented Dr. Rowan's experience with a case of his own, in which an ovarian tumour had been diagnosed as a complication of pregnancy in a single girl. Abdominal section was successfully peiformed. He did not quite see the necessity for Dr. Batchelor's ahdoniinal section if the pelvic diameters were normal. Dr. Balls-Headley agreed tlioroughly with Dr. Batchelor, as to his views on the treatnient of diseased tubes and ovaries. There could be only one metliod of dealing with such conditions — viz., i-emoval. Dr. Batchelor's Ccesarian section opened up the question as to whether, witli our increasing knowledge of abdominal .surgery, we should do craniotomy at all. He favoured the treatment adopted in this instance DISCUSSION. 683 by the President. In his recent experiences in an osteomalacia district in Gei'many, lie had had numbers of women pointed out to him, the subjects of Caesarian section- — as many as five times in the same woman. Dr. Batchelor had not given the pelvic measurements. He agreed with Dr. Eowan's views as to ovaiiotomy during pregnancy — a much safer proceeding than the risk of twisting of the pedicle, with death of the sac or prematui'e confinement. Dr. WuRRALL agreed with Dr. Eowan, especially (as pointed out by Dr. Balls-Headley) as the twisting of the pedicle increased the danger. Like Dr. Batchelor, he thought that oophorectomy checked the growth of fibroids ; but in cases of cancer, he pi-eferred the operation through the vagina. He thought craniotomy, or even the removal of the uterus altogether, applied to the obstetric case of Dr. Batchelor. He preferred No. 2 silk for ligature. On one occasion, after operation, he re-opened the abdomen on the eighth day ; found it full of pus, washed it out, with good results. In his experience, ligatures often remained, and came away after months, with pus in their track. Dr. RowAX was quite in accord with Dr. Balls-Headley's views. He believed that rest and other measures should be tried before resorting to the heroic operation. He had had cases where rest had relieved troublesome ovaries ; but where an ovary was encysted and bound down, and laid a woman up, he felt himself justified in operating. He had done so some sixty or seventy times, and had no cause for regret. With regard to Dr. Batchelor's Caesarian section, he had seen only one case. He had been consulted by a woman, two or three months married, as to why she was not pregnant. He found the vagina occluded, and thought she was not likely to become pregnant. The next time he saw her, she had been in labour fifty-two hours, with no possibility of delivery per vias naturales. He performed Caesarian section, using catgut sutures for the uterine wall. The patient unfor- tunately collapsed the second day, all the sutures having come undone. In reply to Dr. Balls-Headley, he stated the sutures were ordinary carbolised gut. The knots became untied. He would like to ask Dr. Worrall if the absence of foetal consistence did not (in one of his two ca.ses) point to something else 1 Dr. Meyer endorsed the views of the President, their soundness being manifest from his practical and happy results. He begged, however, to differ from the propriety of Caesarian section in the obstetric case. He had met with a very similar case, where two medical men advised section in a woman who had been some forty hours in labour, and on whom forceps and version had been carefully tried in vain. He performed craniotomy with a perfectly successful result. The case read exactly like Dr. Batchelor's. He was not ready to discard craniotomy from the list of obstetric operations. The President said that he preferred Caesarian section in this case, having in mind a similar one — a case of convulsions — where (after weighing the value of a Porro) he delivered by vagina, with the result — ■ death in twelve hours. He had no right to render the woman sterile. Another ))oint was the absence of the husband. As to the propriety of abdominal section in cases of cancer, he was opposed to Dr. Worrall, who favoured the vaginal method. In this case, the broad ligaments being involved, the only question was — Should operation be done at 684 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. all? He thought if so, there was but one way. Although opposed to all authorities, he would (unless with a very capacious vagina, an easily prolapsed uterus, and all circumstances favourable) invariably make an abdominal incision. He saw no reason why a small incision of two or three inches should endanger the operation. You saw what you were doing, and did not injure the ureters. Although statistics were in favour of vaginal operation, it was probably because the worst cases had been treated by abdominal section. He quite agreed with Dr. Eowan, not to operate till other measures had been tried and failed. The dangers of o]ieration at delivery, favoured operation on tumours during pregnancy. Neglected tumours often sloughed. The doubt which Dr. Ptowan had expressed as to the nature of one of Dr. Worrall's cases, was removed by the fact that decidua came away. SHOULD A MEDICAL MAN PRACTISE MIDWIFERY, WHILE IN CHARGE OF A CASE OF PUERPERAL FEVER ? By Jos. C. Verco, M.D. Lond., F.R.C.S. Eng. Joiut Lecturer on Medicine at the University of Adelaide. Honorary Physician at the Adelaide Hospital. There is an opinion current among the people and in medical circles, that the occurrence of a case of puerperal fever in the practice of a medical man demands the discontinuance of obstetric work, until such time as he shall be cei'tainly free from the case and its contaminating influence. This opinion, though somewhat indefinite in its application and partial in its prevalence, is nevertheless a kind of lex non scrijita. The more timid or the more conscientious among the profession ai'e ruled by it. They sacrihce their immediate pecuniary interests by cancelling every forward engagement as it falls due; and since by this very means they gain an unenviable notoriety, they suffer loss, remote, but no less certain. Bolder spirits, or less sincere, ignore this opinion, and continue their work with a still tongue. But in so doing, they play a pei'ilous game — one that, by an accident or a coincidence, may place them in a serious position, where censure, swift and sharp, may be meted out to them, both by the profession and the people; and where they may be involved in the uncertain toils or ruinous processes of the law. Now, if this opinion be valid, the reckless temerity of the bold must be resisted ; but if, on the other hand, it be invalid, the timid must be reasoned out of their fears, and the public must be educated out of their populai- fancy. A full discussion of the question by the leaders of thought amongst us is, therefore, of no little moment, and a plain expression of opinion by tliose most competent to form one. If the Conference unanimously negatives my question, then a practi- tioner can honestly refuse to carry out his midwifery engagements, and PRACTISING MIDAVIFRKY WHILE IX CIIAUCK OF PrEKPKRAL CASES. 685 ran openly appeal to this consensus, in order to prevent the misconception and misrepresentation which such refusal may provoke, and to obviate the necessity for such petty frauds as a healthy right arm, borne for weeks in a sling. If, howevei', this Conference decides in the affirmative, then, while continuing in his obstetric work, its moral svipport will be his, and he will be free from the fear of foi-feitingthe respect of his medical brethren, or ruining his public reputation. And if, to-day, opinions differ upon the suliject, so as to l)e even equally divided, then the /ex non scripta will l>e proven no law whatever, and the individual practitioner will henceforth feel at liberty to follow the dictates of his own enlightened reason and conscience in regard to the particular case, or the special circumstances with which he may be concerned. Whatever, therefore, may be the mind of the Conference upon the issue raised, the result will be beneficial, and with this confidence, I proceed to discuss it. The consideration of the question, T propose to direct along three chief lines, viz. : — (1) What evidence exists, that the puerperal fever under our care has ai'isen from previous cases of the same disease ? (2) What evidence exists, that during the conduct of a puerperal fever case, midwifery may be practised with impunity ? (3) If puerperal fever preclude midwifery work, what shall be our definition of that complaint 1 If the instances with which we ax'e acquainted are known to have originated from similar ones, occurring just before them, this would be a strong argument in favour of abandoning obstetric work in the presence of puerperal fever ; but if they are ascertained to be almost invariably sporadic, and to have generally no causal relation with previous examples, then its continuance would be justified. So also would it be, if we can demonstrate immunity from transmission of the disease, in cases of puei'peral fever ti'eated by the accoucheur, while in full oijsteti'ic practice. And lastly, before we decide upon the necessity of relinquishing midwifery directly Ave are face to face with puerperal fever, let us regard the difficulty of determining with precision which of the post-partum pyrexias must be designated by so terrifying and so binding a name. Our first inquiry then is. What evidence have we, that puerperal fever arises from previous cases of the same disease 1 During the past ten and a half years in South Australia, I have attended 1255 cases of parturition, and have lost four patients only, all of whom died of fever : — One, a primipara, was seen first at eleven o'clock p.m. ; and at 4.15 a.m., as the head, with a large caput succedaneum, was somewhat delayed on the pei'ineum, forceps were applied, and the delivery was easily effected "without perineal rupture. At 5 p.m. of the same day, ?.e., about twelve houi's afterwards, she had a long severe rigor, and after eight weeks of illness, during which she had rigors almost daily, and on some days more chills than one, she died, without developing any objective signs of local disease, except towards the termination of the case, when some albuminuria, anasarca and bed-sores appeared. Regarded clinically, it was as well marked an instance of septicaemia as could be conceiAed. 686 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. How did it arise ? The occurrence of the rigor, with a temperature of 102-6°, within twelve hours of delivery, tends to negative the explana- tion of sapra^mia from decomposition of lochia, especially as it arose during the cool month of August. So also the rigor within seventeen hours of the first examination by the accoucheur, renders somewhat improbable infection by him with an animal poison ; and as a fact, it was learned that the patient had been "out of sorts" immediately prior to delivery, and had had medicines prescribed by a chemist. But on the supposition of contamination by the medical attendant (which in many of these cases is, I think, somewhat gratuitous), whence came the virus ? I had no puerperal fever under my cai'e, but for four days T had had a boy with malignant scarlet fever, who subsequently died of pleural effusion and pulmonary gangrene ; besides another child with acute tibial periostitis (whose subpei-iosteal abscess had been opened however, three weeks), and in wliose ailment there was some pypemic element, as manifested by an abscess some months after in connection with an exfoliation from the humerus. There was also a boil on my own right arm, in the stage of suppuration, about two inches above the wrist. Any one of these three may have been the source of the septic?emic bacilli ; but no puerperal fever origin can be traced. The second was a primipara, delivered with instruments, when the head was at the lower end of the sacrum, without perineal rupture. On the second day, the temperature was 104° F. She had had hardness of hearing from before her delivery. On the fifth day, large diphtheritic patches were discovered in the fauces ; then it appeared, that some soreness of throat had been expei'ienced, though not complained of, ever since the pai'turition. On the day following, the urine was smoky and slightly albuminous. On the 14th day she died. This was evidently post-partum diphtheria. I was not treating any patients with this complaint at the time ; but it was learned, that the mother of the deceased had sufiered from a serious attack of this affection three weeks before. The third was a multipara. The child was born, and the placenta removed by the nurse before my arrival. There had been severe alidominal pain some days before the confinement. She developed symptoms of abdominal inflammation, and died on the eighth day. The fourth was a primipara, whose left hip was fixed by old disease, and who had been afflicted for many years with rectal strictui'e. Tiie l)owel, from about two inches above the anus, was impermeable to the finger, but per vaginam could be felt enlarged, thick, and hard, as high as it could be reached. There were secondary fistuhe in ano, always discharging sanious pus. After thirty-six hours of labour, with the head still at the brim, she was etherised ; the forcejDS were applied, and with great difficulty the head was brought through a pelvis, some- what contracted to the very outlet. After a few days, fever supervened with rigors, and these recurred at intervals for many weeks. There developed in succession — swelling of the left sterno-clavicular articula- tion, the right shoulder, the left temporo-maxillary joint, and the left parotid gland— all without suppuration ; panophthalmitis of the left eye, with collapse of the globe ; discharge of abundant fcetid pus per rectum ; an abscess of the left gluteal region, apparently connected with the bowel ; suppuration in the diseased hip-joint gradually wasted PRACTISING M1D\V1FERY AVHILE IN CHAKGE OF PUERPERAL CASES. 687 her, and she died eight months after delivery. Tliis was an evident puerperal pyjvmia ; nor was the cause far to seek. The diseased suppurating septic bowel, bruised by the passage of the head through a pelvis diminished in its capacity by old morbus coxa?, became inflamed, and provided a focus of infection for the system. These are the only instances of death, or death from puerperal fever, •which have come within my experience in South Australia, and from them I conclude that, in its ordinary sporadic form, the disease can very rarely be attributed to infection f i-om previous cases of a like kind. It would lead me too far, and into too much detail, to enumerate and discuss all the cases of post-partum pyrexia which have recovered, amongst these many hundreds of deliveries. Suffice it to say, I have been unable to trace any causal connexion between any two cases of such feverishness under my care. To what extent we can trace the instances I have given : — They may have arisen from a scarlet fever patient under medical care, from a diph- theria, from a surgical pyaemia, or from a surgical disease such as rectal stricture and fistula? in ano. And does not this possibility press upon our consideration another view of the matter 1 There is not room for doubt, that much of the puerperal fever encountered does originate from such diseases as scax'let fever, measles, diphtheria ; from such surgical aft'ections as erysipelas and pya?mia ; and from the putrefactive matters of the post-mortem room. Hence, to bring the lying-in woman into proximity with patients sutiering from any of these complaints is reasonably regarded as eminently dangerous and reckless. But do we therefore decide that the general practitioner, who has under his care a case of scarlatina, of measles, of diphtheria, of erysipelas, of pyaemia, must, during this period, and for a week or a month afterwards, do no midwifery, lest he should communi- cate puerperal fever? Do we forbid every man who is engaged iii obstetrics admission to the post-mortem room ? To insist on this, would practically exckide the general practitioner from the realm of obstetrics ; for how seldom does he find himself entii-ely free from infecting patients ? And yet if the attendant on a puerperal fever case is thereby forbidden midwifery, because he may transmit the fever poison, for the same reason and to the same extent should the Ijan apply during the conduct of these other infectious and contagious complaints, unless it can be proved that the parturient woman is more susceptible to the influence of the poison of puerperal fever than of any other complaint. No such evidence is, to my knowledge, forthcoming. On the other hand, my own experience, and the usual sporadic nature of the com- plaint, with only an exceptional and very limited epidemic, suggest an origin, not from previous puerperal fever, but from other conditions and complaints which are capable of exciting it. As, therefore, midwifery is not precluded by attendance on these various poisonous affections, neither should it be by the attendance on puerperal fever. Of course, it would be folly to deny the communicability of puerperal fever from a puerperal fever patient, or the communication of the malady in its most virulent form by the accoucheur. For instances are on record of medical men, in whose footsteps death has trodden relent- lessly, and seized in succession every lying-in woman attended by them, until they have relinquished their work. Here the transmissibility and 688 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. the transmission were demonstrated. And here the line of duty is plain. When a man has two or more cases in succession, and he has reason to suspect himself the vehicle of the morbid virus, no considerations of personal financial loss, of undesirable publicity, or of boldness and independent action should be allowed to weigh; but midwifery should be wholly and instantly abandoned. Now it has become a question, not of possible transmissibility, but of certain transmission ; not of a sick woman, who may supply a materies morbi, but of an accoucheur who has a fatal supply about himself, and who is as dangerous in his person, his clothing, his instruments, or his methods, to every lying-in woman he attends, as if a puerperal fever patient were placed beside her in the same bed. Midwifery under such circumstances would be no less than murder. To draw an analogy. Surgical pyaamia is very contagious. Does the surgeon who has under his charge a pyjemic jaatient, therefore, and of necessity, forljear to operate until this case is well or dead 1 Certainly not ! He goes on with his work, and endeavours to prevent any contagion; but should he discover in his operations a succession of fatalities from this cause, would he not readily lay down his scalpel for a while? So should it be with the accoucheur. We proceed now to our second inquiry, viz.. What evidence exists that, during the conduct of a case of puerperal fever, midwifery may be practised Avith impunity 1 As narrated above, four lying-in women have died in my obstetric experience, all fi'om puerperal fever. The first, from septic?emia, lived 57 days, and received 118 visits, or an average of two each day. During its protracted course, three women, previously delivered, were seen 13 times; and 15 others were confined, receiving 108 visits — so that on 121 occasions was I brought into contact with parturient females. The second, from diphtheria, died after 14 days, being seen 24 times. During this period, I paid seven calls to two persons previously confined, and 49 to seven others whom I delivei'ed, making a total of 56. , The third, from inflammation (presumably peritonitis), succumbed in eight days, and was seen 15 times. Two antecedent deliveries were seen five times ; two confined on the same day, 12 times ; one on the next day, six times ; and one on the day following, five times — numbering altogether 28 visits. The fourth, from pyasmia, lived for eight months. But after 10 weeks' attendance vipon her, I was laid aside myself, and she Avas kindly taken in chai-ge by a brother practitioner. During tliose ten weeks, on 63 days I paid 110 A'isits, and delivered no fewer than 22 other women, seeing them 130 times, and two women, previously delivered, four times, or altogether 134. Combining the figures, we get the following reassuring I'esult : — At the very lowest computation, I was at the bedside of those infective patients 267 times; and simultaneously was brought, not into proximity, but into contact, with 57 parturient and puerperal women on no fewer than 337 occasions. And with what efTect 1 Not one of them showed symptoms of contamination in any form, nor developed post-partuni pyrexia sufficient to justify the term "puerperal fever," or to cause danger or grave anxiety. This succession of cases demonstrates the possibility of working amidst these organic poisons without transmitting them. And if to PRACTISING MIDWIFERY WHILE IX CHARGE OF PUERPERAL CASES. 689 these we add the occasions on which I have seen in consultation, and made complete examinations of, patients with serious puerperal fever under the care of otlier medical gentlemen, we get some idea of the impunity with which an indi\idual may move amongst the puerperal miasmata, and handle the puerperal contagia, and yet do no hurt to the healthy lying-in woman. In face of such facts, it is surely almost puerile to ask the question — Was it demanded of me that I should not attend those 57 women? The abandonment of my midwifery was evidently not an obstetric necessity. With such a personal experience in the past, am I required in the future, by any law, ethical or profes- sional, to cancel all my obstetric engagements, should some one patient have the misfortune to develop inflammatory or septiciemic or acute specific febrile symptoms? Does consideration for the well-l)eing of a woman, who trusts herself to my care in the critical time of her delivery, if it be reasonable as well as conscientiovis, demand that she should be transferi'ed by me to other hands ? Under such circumstances, I have no hesitation in answering openly and honestly, " it does not ! " Puerperal fever is I'egarded by some eminent authorities as an excellent name, because it includes all the pyrexias which overtake the lying-in woman, and because it involves no theories. For these reasons, the designation certainly has its advantages for some purposes; l)ut under other circumstances, they are evident disadvantages. If, for instance, it be decided that a medical man, who has under his charge a case of puerperal fever, must not practise midwifery — and puerperal fever includes all post-partum pyrexias — obstetrics will be an impos- sibility. Such a law will plainly demand a definition of puerperal fever, not quite so general, nor quite so free from all theories. Here arises a great difficulty. The term embraces not one specific entity, as does scarlet fever for example, but a medley of diverse diseases. We have seen from the four cases cited, how it may be a septictemia, a pyaemia, a diphtheria, or a peritonitis ; and, without any doubt, it may be a putrefactive sapr^emia, a scarlet fever, a measles, an erysipelas, a metritis, a parametritis, a perimetritis, and probably several other complaints besides. This is sure. The only evidences locally may be a pleurisy, a pericarditis, a pneumonia, or a femoral phlebitis, a so-called white leg, with attendant feverishness. And further, any one of these may exist in any degree of severity, from the least even to the greatest. Are all these puerperal fever ? Are all these infectious ? If not all, which of tliem are ? With reference to some of them, the answer is easy enough theoretically — tho.se derived from scarlet fever, from measles, from diphtheria, from erysipelas. But, practically, it is very difficult, inas- much as the origin is often involved in obscurity. Moreover, what eA-idence have we even then that it is more dangerous than the primary disease from which it was derived ? And if it be not, then scarlet fever precludes obstetrics equally with scarlatinal puerperal fever. Again, there is a floating idea to this effect — if the puerpera have high fever, without local symptoms, it is of grave import to her, and serious as regards contagion. But if there he found a collar of cellulitis round the uterus, here is a local explanation of the continued elevation of temperature. The prognosis is more favourable, and the transmissibility of poison is improbable; in fact, there probably is no poison. But on wliat foundation does such an opinion rest ? So far as I can gather, lY 690 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. not on that of fact, but of fancy. A pelvic cellulitis occurring in an uncomplicated labour must be due to absorption of some sort of poison; and that it should be less virulent, in respect of transmission, than that of a puerperal peritonitis or a puerperal pericarditis, is not quite manifest, though it may evidence a more localised absorption. Frequently after delivery, there is pyrexia ; sometimes with a rigor, at others without. We seek the cause, but cannot find it. In a day or two it disappears, or it may last a full week, and range high, and excite our apprehension, and then subside entirely without revealing- its origin, or leaving any local sequela. In a few days perhaps it recurs, may be continuous or remittent, may be ushered in by rigors, be attended by variable shifting pains, lasting a fortnight, and after giving the patient a shaking and the doctor a fright, terminate in a complete recovery to both. Where shall we find our working rule, by Avhich to measure the degree of infection in these cases? The directions by which to sift the contagious from the innocent are still to seek. There may be cases, such as the first cited by me, in which, after but two or three days, recurrent rigors render a difignosis certain, and establish the contagious nature of the complaint ; but on the contrary, it would be no modesty in us to allow that, in nine out of ten instances of post- partum pyrexia, we are unable to affirm, in the early stages at least, whether we are dealing with an infectious malady or not. And yet, if it ultimately develop positive symptoms, its virus was as dangerous in our midwifery practice during the first few days of our doubt, as it is now during the period of our certainty. One of my patients lived for eight months ; during the last three of which, she was gradually drained to death, by discharging abscesses in the pelvis and the hip-joint. Now we must either insist that infection was present here from first to last, or we must allow some arbitrary line to be drawn, on one side of which is a malignant poison, and on the other side none. The suggestion may arise in our minds, that these difficulties pro- pounded are but captious quibblings. To me, they are far different. They are pi'oblems demanding solution, if puerperal fever is to preclude midwifery. We must know what we mean by the phrase ; otherwise it means nothing, and the law cannot be interpreted ; or perhaps we might say, can be interpreted anyhow. If, whenever a puerperal pyrexia creates anxiety, we cease our obstetric work, this will be an absurdly irregular department of our practice ; and if we defer our decision as to the existence of puerpei'al fever until the case has become critical or hopeless, and not until then take steps for self quarantine, we shall have run the risks of transmitting the disease while the risks were greatest, and have instituted our precautions when probably these were the least requix'ed. The conclusion at which I arrive is this :— A medical man should recognise the special susceptibility of the lying-in woman to the pernicious influence of all animal poisons. He should therefore in every midwifery case exercise cai'e, lest these gain entrance to her system, by adopting simple routine protective measures. Whenever he has under his chai'ge a case of infectious or contagious disease, whether this be medical, surgical, or obstetric, e.g., scarlatina, pyaemia, or puerperal fever, he should regax'd himself as a possible vehicle of transmission or contamination, and should consequently use extra care ON THE ADMINISTRATION OF AN.f:STHETIC.S DUKINfJ LABOUR. G91 in the einployineiit of precfiutioiiary means. But if in his midwifery, a .succession of two or more cases of puerperal poisoning occur, between which he is certainly or pi-obably tlie connecting link, since it is here not a (piestion of pos.sible transmissibility of virus, but of its transmission, not of an infective patient, but of an infecting pi'actitioner, obstetric practice sliould be instantly and wliolly abandoned. By this course the fears and endeavours of the medical man will not be focussed solely on puerperal fevei'. while he overlooks or too lightly regards the equally grave and far more numerous dangers lurking in the multitude of septic medical and surgical maladies with which he is so f recjuently associated. The terror investing puerperal fever, which is a foolish timidity, will be toned down ; and the apathy regarding eminently poisonous common complaints, which is a foolish temerity, will be corrected, and the life of the mother, which for so many reasons should be specially sacred to us, will be pi'eserved. ■SOME REMARKS ON THE ADMINISTRATION OP ANESTHETICS DURING LABOUR. By S. Mabekly Smith, M.R.C.S. Eng. I propose to submit to your consideration a few points on this subject, based on an experience of about 500 cases of midwifery, in which an. anaesthetic has been gi^'en, either in small quantities to diminish pain, or more fully to produce insensibility. Most autliorities, who have written on the administration of anaes- thetics in natural labour, speak of it as an unqualitied success in all cases ; .some of the older writers have equally condemned it. My experience has been, that the results of this practice vary in all degrees from a brilliant success to a miserable failure, owing to the very different effects produced on individuals. As TO THE BEST ANESTHETIC TO BE EMPLOYED. In most cases, the A.C.E. mixture acts admirably in stopping the sensation of pain, and is then to be preferred from its safety. But there are .some patients on whom, from various causes, the mixture is not sufficiently quick in its effect to dull the pain, and in these cases chloroform is preferable from its more rapid action. I have, on various occasions, found the latter succeed, where the A.C.E. mixture has given little relief. It is here presumed that the anaesthetic is given at the beginning of each pain, and removed when it ceases. Where complete insensibility is required, the A.C.E. mixture still seems to be the best agent, or i-ather, I should say, the A.E.C., which is the combination I use in midwifery. Of other narcotics, bichloride of methylene does well. Ether is too slow in its action, and e.scapes so much about the room ; there is also some risk of tire in these cases. lY 2 692 intekcolonial medical confjhkss ok australasia. Of the Risk to Life. Though there is undoubtedly much less danger in giving ansesthetics to pregnant women than to others, from the position of the patient, the small amount given at once, where it is administered only to deaden pain, and the special immunity from heart failure enjoyed by persons in this condition, still I believe that some risk does exist, and that this risk is generally under-estimated. Though I do not personally know of a death under these circumstances, several of my patients have exhibited alarming symptoms, and medical friends ha\ e had the same unpleasant experience. In the British Jfedical Journal of 1878, Dr. Lusk, of New Yoi'k, recoi'ds five cases in which an anaesthetic was given during labour. In two of these, death took place immediately ; and in the other three, the patients were saved with great difficulty. There are other cases I'ecorded where death took place some hours after the labour, and there- fore where it is doubtful whether tlie narcotic was answerable for the fatal result. I attended a patient in four consecutive confinements. On each occasion she took the A.E.C. mixture to relieve pain only, and therefore in small quantities. Twice she took it well ; the third time she exhibited most alarming symptoms of heart failure ; on the fourth occasion she insisted on having it again, and this time there was no trouble. I think this element of danger is an important point. In various places, I have seen anaesthetics administered with the greatest careless- ness, under the belief that a woman in labour cannot be so killed. The Question of Patients Talking Whilst Under the Influence of an Anaesthetic. Writers on the subject seem to confine themselves to the discussion, whether women in this state do or do not talk indecently. Some have said that, where an anststhetic is given only to relieve pain, the amount inhaled is so small that the talking stage is not reached. From my oljservations, patients very seldom do make these remarks, though I have not had qviite the same experience as Simpson, who says that they never do. When they do so it is caused, I think, by the act of vaginal examination ; and anything unpleasant in this way can be avoided by always alloAving a full return to consciousness before an examination is made. As to the amount of vapour inhaled being too small to cause talking, there are women who lose control of their speech with the least inhalation. But, though women in this state seldom speak indecently, they frequently say very foolish things, will tell the greatest secrets, and will answer, generally truthfully, any question put to them. They will quietly, and being apparently to non-professional by-standers in their right senses, make statements damaging to themselves and others; statements which huxe no foundation in fact, and which I am convinced have no existence in their minds when conscious. I am aware of two cases in which trouble arose in this way. In one, there was the unfortunate combination of a woman who talked with the smallest whifi" of an anaesthetic, a mischief-making nurse, and a jealous ON THE ADMINISTRATION OF ANiESTHETICS DURING LABOUR. 693 husband. The semi-conscious patient made some foolisli remark to the doctor, this was duly carried to the husband, there was trouble, and the doctor was never called in again. Some years ago a well-known man was found drowned under suspicious circumstances. Though great efforts were made by the police, no one could be found who had seen the deceased after a certain time at night, though he was believed to have been alive some hours after. Some time after this occurred, I had to attend a woman, who was a stranger to me, in her confinement, and as she was suffering severely, I administei'ed small (juantities of chloroform. Undei* the influence of this, she began to talk tjuietly and rationally about the man who had been drowned. She gave a complete history of him from the time that he was last seen by the witnesses at the inquest almost till his death, stating that she had been with liim all the while. When this patient was well, I told her what she had said. She was very frightened, and was totally unconscious of having said anything, but admitted that her statement was in every particular true. I mention this case as an example of the revelations which may be made by a narcotised patient. Certainly one should be most careful that a woman in this condition does not damage herself or others by her statements. Twice after administering the A. E.G. mixture, I have seen the condition described by Dr. Tom Bird as a'ther mania — that is, that long after tlie inhalation has ceased, perhaps for hours, tlie patient will go on unconsciously saying anything that comes into her liead. This matter of talking is so much more important in these cases of anjvsthesia than in all others, because in these the patient is kept constantly at the talking stage, whereas in others the state of silence is soon reached. Of the Effect of an Anaesthetic on Others in the LviNfi-iN Room. A drawback to the administration of an anaesthetic in some cases seems to me to be this : — Where it is given for a pi-olonged period to deaden the pains, and when tinally some operative measure has to be resorted to, the effect of the vapour on the medical attendant may be sucli that he is not in the best condition, mentally and pliysically, to undertake a critical deliveiy. He is to a certain extent unnerved, his head is not thoroughly clear, and muscularly he is rendered weaker. At all events, I have expei'ienced this condition personally so often that I think there must be others who have been similarly affected. In some rooms, and under some circumstances, it is impossible to ventilate so that the fumes of the anaesthetic are all carried away. Others may be also affected. I attended a lady in a severe labour where cliloroform was used. During its progress, her husband came into the room several times. He became A^ery curious in his manner, and after the case terminated, I found him in another room (juite hysterical. Though a perfectly sober man, he was suspected of being drunk at this time. In another case, I had to get the assistance of the husband in a chloroform case. He was a very strong able-bodied man, but after l^eing in the room a short time, he began to cry, and Ijehave much as the man in the other •case. Both these men were aware of being affected by the anfesthetic 694 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. vapour. I have never seen mother or child aftectecl after the confine- ment. Women in labour must have an exceptional freedom from the sequela? of anjesthesia, though some cases of vomiting are recorded. Do ANiESTHETICS TeND TO PRODUCE PoST-PaRTUM HAEMORRHAGE? There is much difference of opinion on this question ; some authoritie go so far as to say that they prevent it. My belief is, that they have this tendency to cause bleeding. In looking over a record of about 4000 cases, the constant relation between the use of ana;sthetics and haemorrhage is striking. To any woman who has a predisposition to bleed, the smallest amount of any of these agents adds to her danger. Unfortunately in first cases, and often in others, one cannot usually foretell this predisposition. There is however one guide, I think, that is, that there is a pretty frequent relation between those who sufi'er from menorrhagia and those who fiood, though it is by no means constant. If I know that a woman has habitually menstruated excessively, I never, if possible, give her an ana'sthetic. The chance o post-partum ha'morrhage occurring increases with each laljour, and that risk is proportionately made greater by an;esthesia. If I can avoid it, I do not give inhalations simply to relieve pain after the first case, specially as there is usually less need. But here there arises one of the drawbacks of this pi'actice. After once having a narcotic, patients often insist on a repetition of the practice on all future occasions, yet some special risk may have been disclosed from a former experience. If a woman knows she has to bear the pains of labour, and thinks there is no way of escape, she will bear them bravely ; whereas, if she has once had an anaesthetic, she is a coward without it in many cases. Of this I am sure, that whether there is post-partum ha'morrhage or not, after-pains are very frequently caused by anjesthesia, even in first cases ; that is, that though relaxation of the uterus, sufficient to cause severe bleeding, may not occur, yet there is enough to allow oozing into the uterus, causing clots. Of the Effect of this Form of Narcosis in Relaxing the Soft Parts. As a general rule, ana'sthetics have ;i powerful and rapid effect in relaxing the os, but not always. I have seen the deepest anaesthesia fail to do this. I think that the thick rigid ps withstands the effect more than the thin rigid one, and primijiarous cases than multiparous. In cases where the rigidity will yield to nothing else, I have found hypodermic injection of morphia succeed. Inhalation always relaxes and moistens the rigid perina>um to some extent, and generally in a very marked mannei-. The Use of Chloral in Labour. On the whole, my experience of chloral has not been satisfactory. In some cases, doubtless, it relaxes a rigid os ; in many, it fails. In a large number it causes vomiting, and, I belie\e, sometimes relaxes the rigid OS by its emetic action. It is, in my opinion, more dangerous, given in repeated doses, than a general anjesthetic. I have seen two deaths from moderate doses, but not in parturient women. I attended a DISCUSSION. 695 patient in labour with a rigid os ; twenty grains of chloral were given in Liebreich's Syrup. Twenty minutes after, the os not having yielded, the dose was repeated. The woman then got into the most alarming condition with the symptoms of chloi'al poisoning, and was with difficulty saved. Patients made semi-unconscious, sometimes become very noisy and unmanageable ; in this case, it is better to stop the inhalation, however much they object. Giving an anaesthetic for natural labour is often a severe tax on the medical attendant. However tired he may be, he has to sit perhaps for hours watcliing for the commencement of each pain, to give the looked-for whiti' — the more tempting process being to go to sleep in anotlier room. The cases above all others in which anaesthesia gives relief, and does direct good, are those in which there is one continual pain without cessation, pain peculiarly hai'd to bear and nearly useless, caused by irregular contraction of the uterus. A few inhalations make a complete change, the pains become bearable and defined, there is the regular rise and fall with an interval, and the labour progresses. In conclusion, I would advocate the use of aniesthetics in operative midwifery, and in natural labour, where it is required, and where it is practicable. I say, whei'e practicable, because there is a vast difference between giving them where there is the assistance of another medical man, or of a skilled nurse in a town, and being away in the bush with practically no help, and where the proceeding may be strongly objected to by the friends. In such cases, it is often better to do without them. In natural first confinements, I would administer an anaesthetic for any of the following reasons : — Either that the patient desired it, or that the pain was excessive, or to relax the soft parts. In natural multiparous cases, I would not give it if I could avoid doing so. In all operative cases I would give it, except where forceps are used with the head on the perina?um, when it is not required, unless the perinaami be rigid and dry, then the practice is invaluable. DISCUSSION. Dr Balls-Headley agreed ^\ith Dr. Verco's conclusions, but pointed out the necessity of practitioners taking every precaution to protect themselves against dangers of transmission. He recommended even so strong an antiseptic as a solution of corrosive sublimate of ten grains to the pint. It must be noticed that Dr. Verco's statistics were those of private practice, and so were different from those of hospital practice. The common cause of so-called puerperal fever was the transmission from one septictemic patient to another. Antiseptic midwifery prevented septic;emia. The lines of temperature in hospital charts i)efore and since the introduction of antiseptic treatment, undoubtedly proved this. Dr. Bkummitt had had a fairly wide experience in the country, having attended 1000 cases of midwifery during the period covered by 696 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Dr. Verco's paper. He had seen only one case of true puerperal feve)-, a fatal one, in a house which contained a case of malignant diphtheria. The degree, with which lying-in women sufiered from proximity to contagion, varied. He rememl^ered finding a child with typhoid lying in bed alongside its recently confined mother. The woman escaped scot-free with a straight line temperature. Another child (in a different case) had scarlatina, without in any way affecting the mother. In his district, he had known no year free from zymotic disease ; but as far as he knew, it had not affected lying-in women. Dr. Eugene Anderson, Resident Medical Officer of the Women's Hospital, Melbourne, pointed out that from May 1877 to August 1888, there had been 688 women confined in the institution; and that of the four deaths that had occurred among them, only one was due to puerperal fever. This, he thought, proved that he himself, combining as he did the dual duties of infirmary and midwifery departments, had conveyed no puerperal fever to his lying-in patients. The strictest antiseptic precautions were observed. He laid great stress on thoroughly cleaning the nails with a nail brush. He mentioned the case of a woman who had been brought to the hospital with scarlatina, and though she was seen (necessarily) in the first instance by nurses, no harm had ensued. Dr. WoRRALL agreed with the conclusions of Dr. Verco, provided rigoi'ous antiseptic measures were adopted, as indicated by Dr. Balls- Headley. He thought that Dr. Verco had proved that other forms of blood-poisoning than puerperal fever may occur from contagion. Dr. J. W. Dunbar Hooper could speak from his experience as a previous Resident Medical Officer of the Women's Hospital for two years, and a member of the present Honorary Staff of the Midwifery Department. He agi-eed with Dr. Verco, provided antiseptic pre- cautions were employed. He had seen a woman affected with puerperal fever lying in the same ward as another not so affected, without conmmnicating puerperal fever to the latter. He thought a good deal of liarm was done by ignorant midwives, who should be made to pass examinations, and show their knowledge of the use of antiseptics. Mr. E. M. James agreed with Dr. Hooper, and approved of tlie registration of midwives, and of cases also. Puerperal fever cases should be traced. He believed that lacerations of the cervix, by presenting a solution of continuity, were a cause of feAer by absorption. Dr. Nyulasy asked if Dr. Verco believed that bad drainage was a cause of puerperal fever. Dr. Meyer, as one of the pi'esent Honorary Staff of the Midwifery Department of the Women's Hospital, and a previous Resident Medical Officer of over four years' standing to that institution, could agree thorouglily with Dr. Verco. Dr. Bright, of Hobart, differed from the voice of the meeting. He thought that where a medical man had a case of puerperal fever, he sliould give up attendance on liis other patients for at least a month, especially in towns. Dr. Batciielor pointed out that we must not overlook the possibility of mischief existing in a pati(!nt before the onset of puerperal fever. In Dr. Verco's first case, the mischief might have been tubal. In the second case, the unilateral pain pointed to tubal mischief. These causes UTERINE PREGNANCY SUPERVENING ON ECTOPIC GESTATION. G97 might account for a good many sporadic cases. He wished to correct an erroneous impression in Dr. Verco's mind, that he (Dr. Batchelor) did not believe in the existence of pelvic cellulitis. He did say such a condition was excessively rare, except as an accompaniment of acute general septic conditions. He thought the term, " puerperal fevers," was better than " fever." Dr. Verco, in reply, was very thankful to the members for their cordial support of his views. He had feared opposition. He wished it to be understood, that he did not say that puerperal fever cannot be conveyed from one patient to another. He never attended a case without previous disinfection ; even if the child had been born before his arrival, he used antiseptic measures before commencing treatment. We might for our own peace of mind (in the face of puerperal fever developing in a patient), hand over our cases to a brother practitioner. Such a proceeding would be all right, if we knew that he had nothing likely to be a source of contagion ; on this point, we could not be sui'e. In reply to Dr. Nyulasy, he thought bad drainage a likely cause of puerperal fever. A CASE OF UTERINE PREGNANCY SUPERVENING ON ECTOPIC GESTATION, WHICH HAD PERSISTED FOUR YEARS. By Thomas Chambers. Lectiu'er on Midwifery and Diseases of Women at the Sydney University. Senior Physician to the Department for Diseases of Women at tlie Sydney Hospital. Mrs. ^I., a^t. 32, mother of three living children, youngest two years old ; always had lingering labours. She engaged Dr. Jones, of Ashfield, to attend her fourth confinement, which was expected in March 1884. When two months pregnant, she had a severe attack of pain in the right iliac region, which passed off in about a week without any special treatment beyond rest and sedatives. When four months gone, she went to Grafton by sea, and soon after her arrival there she was seized with very severe crampy pains in the right side, and urgent vomiting, which kept her in bed about a month, fixed on her right side — this being the only position compatible with anything short of the severest agony. In the early part of the sixth month, when preparing to return home, another attack of severe pain and vomiting came on, which prevented her return. From this time the attacks were frequently repeated, with more or less severity, until the full term of gestation was completed, when strong pains, similar in all respects to her former labour pains, came on, and continued for forty-eight hours. She herself believed, and the doctors (three) who attended lier believed her to be in labour. 698 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. At the end of forty-eight liours she had a severe attack of faintness, with loss of vision and a sense of approaching death, with a very peculiar fluttering, as if something was loosely moving about in the abdomen. At this time sevei'al attempts were made to deliver her, but, I need scarcely add, without success. These unpleasant symptoms gradually subsided, when a discharge of blood from the vagina appeared, much in the same way, and in about the same quantity, as had followed her former confinements. Several clots were passed, one being specially noticed from its peculiar formation and density, having the length and outline of a child's forearm. By the end of the tenth week she had I'ecovered sufficiently to enable her to return home, when she again came under Dr. Jones's observation, and shortly after her return I had an opportunity of seeing her with him. She could now get about her house, and attend to her family affairs without pain or discomfort. The lower zone of the abdomen was occupied with a globular tumour, resting on the pelvic brim, inclining decidedly to the left side. It was s})herical in outline, perfectly smooth on its surface, with a boggy feel closely resembling a dense colloid tumour, but by deep pressure the fcetal outline could be cleai-ly traced. The tumour, which had a diameter of seven and a half inches, was to some extent movable — ■ that is, it moved like a body anchored to a fixed point. The inference was, that it had formed attachments to the antero- lateral aspect of the abdominal peritoneum. The uterus was normal in size, but the fundus was less movable than the cervix and body. As she felt herself to be in good general health, and able to attend to her domestic afiairs, she absolutely declined to submit to any surgical interference ; and although she was warned as to the risk's involved in delay, she stoutly resisted any operative procedure. The patient continued to enjoy excellent health up to the end of the year 1887, when she again consulted Dr. Jones, believing herself to be pregnant. This belief was confirmed by Dr. Jones, and she continued pretty well until the early pai*t of June 1888, when she had an exhausting attack of diarrhoea and vomiting, accompanied by severe abdominal pain. The abdomen was greatly distended and veiy painful, with great mental depression ; and her sufierings were so acute and exhausting, that she earnestly desired something might be done to relieve the painful distension. I saw her in consultation with Dr. Jones on June 21, and found the aspect of afiairs greatly changed since my last visit. The severe attack of diarrluea and vomiting had much exhausted her, the abdomen was distended to an extreme degree, and exquisitely sensitive, even to the most careful manipulation. The uterus was placed obliquely across the alxlomen, with its fundus directed towards the spleen ; the dorsum of the child lying immediately under the median line, with its head resting against the right ilio-pectineal ridge. The tumour was lifted com- pletely out of its original position, and relegated to the right hypochondriac region, immediately under the liver. Per ^■aginam, the cervix utei'i could be easily reached by tlie examining fingei", the os uteri was sufficiently patent to admit the finger, and the cranial arch could be felt resting against the right half of the pelvic brim. Ifo trace of the tumour could be felt within the pelvic area. UTERINE PREGNANCY SUPERVENING ON ECTOPIC GESTATION. 69^ The important question now to be determined was — What was best to he done in the interests both of mother and child? That something must be done was clearly manifest. Upon which factor should we act? I'pon the tumour, leaving the uterus and its contents intact ; upon the uterus, leaving tlie tumour for a future occasion ; or should we leave both alone, and let nature take her own course ? If these important questions could have been discussed under less urgent and nwre favourable circumstances, the difficulty would have been reduced considerably. Having carefully considered the unfavourable circumstances surround- ing the case, the condition and position of the uterus and its contents (the evident indications that nature had already detei"mined the question as to which factor she intended to act upon, in order to relieve herself of an insupportable burden), the changed position of the tumour, the great uncertainty as to its attachments, as well as the difficulty of dealing with it under existing circumstances ; having, I say, carefully balanced these several risks, we came to the conclusion that, if one course offered fewer risks than another, it was to follow the manifest indications of nature, viz., to empty the uterus by the induction of premature labour. The fcetus having passed the seventh month of utero-gestation, and as its heart sounds counted 144, a female was diagiiosed, which was regarded as a favourable element in the case. On June 23, Dr. Jones passed a soft gum elastic catheter up between the uterine wall and the membranes ; labour pains came on with increasing regularity and force in about twenty hours, and a living female child was born twenty-four hours after the introduction of. the catheter. Post-partum haemorrhage necessitated the mechanical removal of the placenta, after which the uterus contracted pretty lirmly. I saw the patient four hours after the child's birth ; the uterus had relaxed considerably, and its cavity was distended with coagula, which were removed by gentle compression, and the uterus and the vagina were well irrigated with vinegar and water, after which tlie uterus contracted fairly well. The abdomen was a good deal distended and painful : pulse 1 20, lessened in volume; temperature 101 "4°, and respirations 28. The face was pinched and anxious, and the skin covered with perspiration. These early symptoms pointed to peritoneal iri-itation of an asthenic type, and to a doubtful prognosis. Next day, the symptoms which usually characterise asthenic puerperal peritonitis were in full force — • viz., abdominal distension, acute pain, urgent vomiting (green vomit), exhausting diarrfuea, dry tongue, urgent thirst, high temperature 103"5°), quickened pulse without power (132), shallow respirations (36 to 38), great facial anxiety, and fixity in the dorsal decubitus, with flexed lower extremities. Tn this condition she continued, fluctuating from day to day, until Saturday, June 30, when she quietly succumbed, just a week from the introduction of the catheter. A post-mortem examination was made about eighteen hours after death by Dr. Wilson, Pathologist to Prince Alfred Hospital, and Demonstrator of Anatomy at the Sydney University. The peritoneal cavity contained a quantity of dark grumous fluid, mixed with lymph shreds and pus. The peritoneum around the ca?cum was much congested^ 700 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. and studded with dark patches of effused blood. The uterus was well contracted, and liad descended well into the pelvis, although its sinuses contained pus. The tumour extended upwards to the ninth rib (right side), overlapping the ascending colon, to whicli it was attached by recent adhesions; it was also connected by tibrous bands, of old standing, to tlie meso-colon and small intestines. In the immediate vicinity of the tumour, the coils of the small intestines were matted together by recently eS'used lymph, at a point where the sac containing the foetus had given way, apparently from ulceration, and the cranial bones were protruding through the opening. The tumour was anchored to a long pedicle, which appeared to have undergone gradvial elongation, by the enlarging uterus exercising continuous upward pressure upon it. The pedicle was triangular, having a very bi"oad base, which involved the right broad and round ligaments, the right Fallopian tube and ovary, the round ligament forming its right free border. The sac, uterus, and appendages were removed, and cai-efully examined by Dr. Wilson, who, in answer to a list of questions, kindly replied as follows: — (1) Character of cyst and its site — originally tubal, now in the folds of right broad ligament. (2) The containing sac is too much condensed to say whether it consists of the original membranes ; but the lining- membrane is, in part at least, original. (3) Right ovary is intact, and appears to be atrophied; the right tube is intact from the cyst to the fimbriated extremity; the proximal uterine part is ati'ophied and closed. (4) I am of opinion that puerperal peritonitis, together with septicfemia, were the causes of death, and think it probable that the peritonitis preceded tlie septicaemia, though it may have been otherwise. (5) 1 do not believe that, apart from the subsequent septic infection, the cyst contents which escaped into the peritoneal cavity were the causes of the peritonitis; but they may have been predisposing causes. (6) The ftetus belongs to the macerated variety. (7) Tlie left ovary contained a coi'pus luteum. Having already occupied more of your time than I originally intended, I will not trespass much longer; but I cannot refrain from offering a remark or two. In the first place, it may be asked — "What were the causes of the severe pains at the end of the second month ? I am inclined to the opinion that pai'tial rupture of the muscular wall of the tube occurred, while the ovum remained intact, and if the true cause had been recognised, it would have been good practice to have performed laparotomy, and cleared out the peritoneal cavity. Then, with respect to the formidable array of symptoms which presented themselves at the end of the fourth month, it may be fairly inferred that a second and more extended rupture occurred, but did not involve the amniotic coat on the placental site, at any rate to any considerable extent. Laparotomy would, at this juncture, have been in accord with modern views, if tlie nature of the case had been made out; but extra-uterine gestation does not appear to have been suspected, notwithstanding tlie presence of a chai-acteristic symptom, viz., a sanguineous discharge from the vagina, more or less continuous. What were the precise changes wliicli took place after tlie cessation of the labour pains, when the faintness, loss of vision, and a sense of impending death — witli a feeling as if something was moving loosely in the aVjdomen — occurred, it is difficult to conjecture? The patient UTEIUNK PUEGNANCY SUFEKVKXING 0\ iiCTOfIC (iKSTATIOX. 701 was satisfied tliatthe child was alive previous to this attack, but did not feel its movements after the urgent symptoms had passed away. It is, however, within the range of possibility that the membranes were more completely ruptured than heretofore, permitting the escape of the liquor amnii, and perhaps tlie child, in part, into the al)dominal cavity ; that the child died ; and the ruptured cyst was repaired by the inflammatory changes that supervened. AVith respect to the clot passed per ^"aginaln, of peculiar formation, size, and density, having the length and outline of a child's forearm, we may fairly assume this to have been the uterine decidua, although it does not appear to ha\'e l)een recognised by the medical men in chai-ge of the case. When the patient returned from the countiy, her general health had so much improved, and her personal inconvenience was comparatively so little, that slie positively declined to permit of any surgical inter- ference, although it was represented to her that the retention of the tumour might eventually prove to be a source of danger. While, in some cases, toleration of a gestation sac may be established after the sac and its membranes have become calcified, and may be retained, as an inert body, for a long series of years, — (Sappey met with a case where a foetus had been thus retained, in this way, for more than half a century) — nevertheless, it is well-known that tliis process of calci- fication, even when established, is often impei-fect, and the sac may rupture inopportunely, and prove disastrous to the interests of the unfortunate patient. Hence, it is a wise precaution to remove the tumour when a favourable opportunity offers. It is quite possible that rupture would not have taken place in this case had irot uterine pregnancy supervened. But the most important questions yet remain to be noticed, viz. : — ■ What was the best course to adopt when interference became a necessity ? Upon which factor ought we to have acted 1 Upon the tumour, or upon the uterus? These are important questions, upon which I should be glad to hear an expression of professional opinion, especially as we possess so little information as to the best method of dealing with cases of this kind ; indeed, I have not been able to find a similar case on record. Looking at the case from an after-event point of view, it may be said that, to have removed the tumour, as we should an ovarian tumour complicating pregnancy, would have been the best mode of treatment. I was not of this opinion before the event, nor am I now, and for the following reasons : — (1) Because the uterus had evidently made preparation for relieving itself of its contents, as indicated by the conditions already mentioned, and I am one of those who hold the opinion that in cases of perplexity we should, if possible, ascertain nature's plan of dealing with her difficulties ; and if her method is practical and reasonable, we should, as far as possible, aid her in carrying out her conservative designs. (2) Because Ave liave the fact on record, that toleration of an abdominal gestation sac may have become so well established, that labour, even at full term, may be completed without injuiy to the sac or its contents, even if the uterine gestation is several times repeated 702 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. (3) Because I Ijelieved the patient's general condition and surroundings were exceedingly unfavourable for abdominal section — a belief which was well sustained by the after- death examination, which revealed the facts that the fcetus belonged to the macerated variety ; that the sac had given way, and its Huid contents had escaped into the peritoneal cavity. How long the cyst had been ruptured could not be ascertained ; but it may reasonably be inferred, that the escape of the fluid contents of the cyst into the abdominal cavity was the exciting cause of the exhausting attack of diarrhoea and subsequent peritonitis, which contributed so materially to the disastrous i-esult. If rupture of the sac could have been diagnosed, then abdominal section should have been undertaken immediately, notwithstanding the unfavourable circumstances surroundinc: the case. A MODIFICATION OF MARION SIMS' OPERATION FOR METROTOMY. By George Rotiiwell Adam, M.B., Ch. M. Edin. Hon. Physician, Midwifery Department, Women's Hospital, Melbourne. It is not within the scope of this paper to enter upon a discussion on the merits of metrotomy ; suftice it to say, that the operation has now been thirty years or more before the profession, and is still extensively practised in some form or other. My aim is rather to bring tlie operation up to the scientific requirements of the day, and thereliy reduce its possible dangers to a minimum. The patient is directed to have the pudenda, including the inside of the thighs and each groin, thoroughly well washed with soft soap a}id hot water, the vagina to be syringed out with water as hot as can conveniently be borne, the night before, and the morning of the operation. The patient is placed in Sims' position on a stout table. The pudenda, insides of thighs and groins, are then well washed with a 1 — 1600 solution of perchloi'ide of mercuiy, diluting the solution to about half this strength to syringe out the vagina. The instruments and sponges are kept in a 1 — 20 solution of carbolic acid. A Sims' speculum, or wliat I prefer for vaginal surgery, Semon's perineal retractor, is then introduced, the cervix brought into view, and seized with a vulsellum, which is steadied by an assistant. An attempt is then made to introduce a sound tlii'ough the cervical canal into the utei'us, in order to ascertain the lie of the viterus, the condition of the cervical canal :ind internal os. If the external os is so narrow that a sound cannot enter, its posterior lip may be incised by a curved sharp-pointed bistoury. MODIFICATION OF MARION SIMS' OPEKATION FOli METROTOMY. 703 The posterior wall of the cervix is then divided at one cut with a pair of Hart's scissors, nearly up to the vaginal roof. The hjemorrhage is usually slight, but after sponging, bleeding points are easily seen and secured by pressure forceps. General oozing is readily controlled by a strea^m of liot corrosive solution. The tip of the left forefinger is now pushed up the canal as close to the internal os as possible, and a curved probe-pointed bistouiy is slipped along it through the internal os, and its superficial fibres lightly notched, anteriorly and posteriorly. I the}i enlarge tlie internal os, by stretching it with a four-bladed dilator with spring handles, which enables the operator to accurately gauge the amount of tension used. The vagina is again washed out, and all clots removed by careful sponging. Three or four sutures are noAV introduced into each half of the divided cervix, so that the endo-cervical mucous membrane is united to the mucous membrane on the vaginal aspect of the neck of the uterus, thus practically covering in the cut surfaces of eacli half of the divided cervix. For this purpose, I use curved needles on long handles, similar in pattern to those employed in the operation of cleft palate. No. 3 silver wire makes a good suture, being pliable and sufficiently strong, as there is little strain on it. It is well to leave the ends long enough to reach to just within the vaginal outlet, taking care to bend up the points in order that the vagina may be uninjured. In this way, the removal of the suture is more easily •effected. The vagina is now thoroughly washed out with corrosive solution, carefully sponged dry, and packed with absorbent iodoform wool. The whole operation need not occupy more than twenty or twenty-five minutes. The after-treatment consists in keeping the patient in bed for seven or eight days, after which she may be allowed to get on to a sofa, and on the fourteenth day she is usually convalescent. I remove the vaginal packing on the second day, and have the vagina then daily washed out with hot carbolised water until after the sutures are taken out, which is done on the sixth or seventh day. The advantages of this method of j^erforming metrotomy are: — (1) It is aseptic, in so far that the vagina is thoroughly cleansed, and the cut sui*f aces are closed in and encouraged to heal rapidly. (2) Ha?moi'rhage is effectually controlled by the fact, that those parts from which any considerable bleeding can occur are bi'ought within easy view, and secondary hiemorrhage is obviated by the closing in of the cut edges. (3) The object of the operation is more effectually carried out, inasmuch as closure of the cervical canal is abundantly provided against by the forcible teai'ing of the superficial muscular fibres of the internal os (wliich act as a sphincter) and the suturing of each half of the divided cervix. (4) It is in accordance with modern scientific requirements, whereby tlie sense of touch is not alone unnecessarily relied on, but a precision is given to the can-ying out of details which other methods in vogue do not possess. The homely adage, " the proof of the pudding is in the eating," is axiomatic; so in surgery, an operation must be known by its results. Of five cases I have done by this method, two were where steiility was the prominent trouble, and in both instances the result justified the procedure. The other three were for dysmenorrhoea. In two, the relief was all that could be desired ; in the third, the result was a failure, probably due to want of care in selecting it as a suitable case for 704 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. operation, as there was a fibroid gi'owth in the posterior wall of the uterus, on which I now think the dysmenorrhcea depended. Not one of these cases gave me the least anxiety during convalescence. The temperature and pulse, after the reaction from the operation subsided, continued normal throughout, and the patients suffered no incovenience beyond the confinement to bed. In contra-distinction to this, within the past year I have seen thi^ee cases, in which the metrotome was used, do very badly. One had alarming hfemorrhage; the other two were confined to bed for many weeks with a sharp attack of peri-uterine inflammation. In conclusion, I would say that any who may try this method of doing meti'otomy will find it a distinct advance on the ordinary methods in vogue. THE MENSTRUAL FUNCTION— ITS INCEPTION, DURA- TION, AND CESSATION, COMPARATIVELY CONSIDERED. By Eugene Anderson, M.D., B.S. Melb.; L.R.C.P. et S. Ed. For two years Senior Resident Surgeon, Women's Hospital, Melbourne. In casting round for a subject worthy the attention of so important a meeting of the medical profession as this, it occurred to me that a consideration of some points connected with menstruation might be of interest, especially if those points we)-e particularly worked up from an examination of the suiTOundings of that function as exhibited by those born in the colonies, as compared with those born in the United Kingdom. For this purpose, I have taken the records of the Women's Hospital, Melbourne, and from over 1200 cases I have drawn out the following results and conclusions. Comparatively, I have also considered throughout the differences which exist in the perfoi'mance of this function, when it is first established, and later, in more mature years, when marriage and child-bearing have in most cases brought their influences (if any) to bear. I have taken particular note of the following points, viz. : — The age at which menstruation is established, its regularity or otherwise, the number of days which the flow lasts, the amount of accompanying pain, the age at which menstruation ceases, and the duration of menstrual life. These points I desire to now shortly bring before this Congress, hoping that this paper may shed some few rays of light on this important function : — The Average Age at which Menstruation begins. In 1220 cases, the average is 14-71. The whole of these were born in the colonies, with the exception of 132 cases, in which the age was 14*73. The average mean temperature of Melbourne is 57° F., and of the capitals of all the colonies it is G0'5°, while that of THE MENSTRUAL FUNCTION. 705 Great Britain and Ireland is 45'4° ; thus a difference of 15"^ in temperature is accompanied by an earlier onset of the flow of only '02, or one week less than is, I think, ordinarily supposed to be the case. Hart and Barbour give from 13 to 15 as the usual age for the home country; while Playfair states that, in temperate climates, it generally commences between the fourteenth and sixteenth years, and is somewhat earlier in tropical, and later in very cold countries. My number of cases is certainly not large, but, as far as they go, tend to show that the difference is not so great, according to tem[)erature, as is often ascribed to this influence. A few particulars are given of the most notable cases met with in my examination of our records. Thus the earliest age at which men- struation commenced was 8}, years. This woman was regular from the start; married at 19, had one child, is 30 now, and is irregular, with a 7 to 8 weeks interval. In another case, pet. 25, the menses have never appeared ; married at 1 8 ; has never been pregnant ; no treatment was considered necessary ; uterus and ovaries present. Another, jet. 34 now; is married; never has been pregnant; menses have never appeared, though there is no pathological condition to acconnt for their absence. Another, set. 18 now; no menses have appeared; was married at 16, and has had two children, the last very recently. This is a curious case, and it would be interesting, if her history could be followed, to see if they appear later. Of 1160 cases— 1 began at 8.1,, 7 at 10, 20 at 11, 91 at 12, 154 at 13, 267 at 14, 254 at 15, 164 at 16^ 109 at 17, 54 at 18, 13 at 19, 12 at 20, 3 at 21, and 2 at 23. (a) Question of Regularity, or otherioise, at Incejyfion of Menstruation. In 1170 cases, 308 or 26 per cent, were irregular then, while 862 or 74 j)er cent, were regular. The average age at which menstruation began in those who were irregular was 14'82, or "11 higher than the general average — a slight indication that late appearance rather predisposes to irregularity. I find that in 1177 cases, the average number of days which early menstruation lasts is 4*42 days. (h) Amount of Pain with Early Menstruation has been considered as None, Some, Great, and Very Great. Out of 1144 cases : — No pain occurred in 484, or 42 per cent. Some ,, ,, 352, „ 31 ,, Great „ „ 289, „ 25 „ Very great „ 19, „ 2 „ (c) Amount of Floio in Early Menstruation is Grouped under the Heads of Very Scanty, Scanty, Usual, Free, and Very Free. In 1109 cases:— Very scanty in 34, or 3 per cent. Scanty „ 235, „ 21 „ Usual „ 450, „ 41 „ Free „ 346, „ 31 ,, Very free „ 44, „ 4 While working out these results, I thought it advisable to enquire if scanty or very scanty flow is associate*.! with more pain than when the Iz 706 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. amount is usual or free, and found, from a consideration of 228 cases, that scanty flow is associated with more pain in 9 per cent., while very scanty flow is accompanied by veiy great pain in 21 per cent, more (33 cases) than the average. Later Menstruation. The average age (of 940 cases) at which this is taken is 31, and the percentage of married to single women is 80 per cent, to 20 per cent. (1) Its Regularity, or Otherwise. In this, I have taken every woman as regular who menstruates every 2, 3, 4, 5, or 6 weeks habitually. In these 940 cases, 65 per cent, are regular, and 35 per cent, irregular. Comparing this return with the results obtained in early menstruation, it will be found that 9 per cent, more are regular in their early, than in their late performance of the function ; tending to show that, in later life, menstruation is a good deal more likely to be irregular, than at its onset. Hart and Barbour state that it is regular in 87 per cent, when once established. I suppose the discrepancy in these returns is due to the fact, that Hospital patients are so often affected with various uterine and ovarian troubles, which tend to cause irregularity. (2) The Frequency of Later 3fenstruation. In 621 cases who are regular : — 29 menstruate every 2 weeks, or 5 per cent. 88 „ „ 3 „ 14 „ 471 „ „ 4 „ 76 OK (\ 1 ■^" >> 5J " >> ■* 5) Thus, three-quarters of all those who have any regular interval are unwell every 4 weeks, while every 3 weeks is by far the next in frequency. Seventy-one per cent, of all women are stated to menstruate every 28 days. (3) The Number of Days tohich Later Menstruation lasts. Hart and Barbour consider it abnormal if the flow last less than 2 days, or more than 8. In 848 cases, I obtained an avei-age of 5 days, closely agreeing with Playfair (who gives 4 or 5 days for the Home Country, while some French writers give 8 days for that country), and being an excess of rather more than half a day over the duration of its continuance in early life. (4) Amou7U of Pain in Later Menstruation. In 853 cases : — No pain in 212, or 25 p.c. as comi)ared with 42 p.c. in early menstruation. Some „ 270, „ 32 „ „ „ 31 „ „ „ Great „ 316, ,, 37 „ ,, ,, 2a „ ,, „ Very great 55, „ 6 „ „ „ 2 „ „ ,, Thus late menstruation is found to be associated with pain of a varying degree in 17 per cent, more than in its earlier manifestations. THE MENSTRUAL FUNCTION. 707 (a) Aiiiuunt of Flow in Later Maistniation. The average amount of blood lost is very variously estimated. Hi])pocrates tliouglit IS ounces, wliich is much too high; and proVjably Playfair, witli 2 or .3 ounces, is more near correct. In 815 cases : — Flow was A^ery scanty in 40, or 5 p.c. as compared with 3 p.c. in early. ,, ,, fecanty ,, 1J4, ,, L4 ,, ,, >> -'i ;< )> „ „ Usual „ 227, „ 28 „ „ „ 41 „ ,, ,, J- ICC ,, .J I -J, ,, >)^J ,, ,, ,, !^i ,, ,, Vervfree S2 10 4 Comparatively, The flow is of usual amount in 28 per cent. Late, and 41 per cent. Early. Is below the average in 29 ,, ,, ,, 24 ,, ,, Is above the average in 4.5 „ „ „ 35 „ ,, Instituting a general comparison, it will be seen that in eaily menstruation the flow is more regular, lasts a shorter time, is accom- panied by less pain, is of a normal or usual amount much more often (13 per cent.), is below the normal less often (5 per cent.), and above the normal less often (8 per cent.) than in later menstruation, where the converse holds good. The very great majority of these women in "wliom later menstruation is taken, being married, and having had children, it seems that marriage and parturition tend to cause irregularity, a longer duration, more pain, and more variation from the usual flow than single life, (10) Age at tvhich Menstruation Ceases. This is generally given as from 40 to 50, and Raciborski states that the largest number of cases of cessation are met with in the forty-sixth year. I have taken out 95 cases, and their average is 46 years ; 4 of these ■women were single and had no children, and in them it ceased at 46^ years. Of the 91 married women, 12 had no children nor abortions, and in them it ceased on an average at 42i years. The average age at which menstruation began in all cases was 15 j years, so that the duration of menstrual life was 30f years ; in the single women it was 32 years, and in the 12 nulliparous married women it was 27'4 years — 3 years less than in parous married women, or longest in the single, and shortest in the married woman with no children. The greatest age at which it ceased was 60, and in this case it began at 13^, so that her menstrual life extended over 46^ years; she was married at 30, and had 2 children. The earliest age at which cessation took place was 28 ; in her it began at 15, married at 23, has never been pregnant, her present age being 43. It is generally said that women, who commence to menstruate when very young, cease to do so at a comparatively early age ; so that the average duration of the function is about the same in all women, those who commence late ceasing later than usual. I have tested this as follows : — In 37 cases, in which it began at 16 or over, the average age at which it ceased was 45?, years, and the duration of menstrual life was 28 years. In 16 cases, in which the function began at 13 or under, the age at which it ceased was 46.', years, and the average duration of their Iz 2 708 INTERCOLONIAL MEDICAL CONGRESS OB' AUSTRALASIA. menstrual activity was 34| years. These results show that if menstrua- tion commences much later than usual, the average duration of its activit}' is 2f years less, and the age at which it ceases is 6 months less ; while if it commences much earlier than customary, its average duration is 3^ years more than usual, and the age at which it ceases is 6 months more than the average of all cases; so that I agree with Playfair and others, that the earlier the menstruation commences, the longer it lasts — early menstruation indicating an excess of vital energy, whicli continues during the whole childbearing life. I have taken out in addition two points of general interest, though not actually included properly under the title of this paper : — (c() The average age at which marriage took place was 20'79 years. The youngest was married at 10, menses began at 15, had 1 child, is 28 years old now, and regular. The oldest was married at 46, she began to menstruate at 15, has had no children nor miscarriages, is 49 now, and regular. Another married at 12, menses began at 14, had 17 children, and at 47 is regular. {/>) Average number of children which parous married women bore, is 4 '48 (not counting abortions). A few remarkable cases of excessive childbearing are given : — One had 17 Menses began at 12 J» )) -l^ >) J) 1 '^ 1 'i >> 5> ^''' n J) 15 15 1 5 It will be noted, that the average age at which menses first appeared in these prolific women was 14], just about the regular time, while they all married very early, averaging 17i years; the latter fact, in connection with the large number of children they bore, is perhaps worthy of consideration. 12 Married at 18 Menses ceased at 49 12 141 „ 15 GO At 40 is irregular IG" 13 „ 18 „ 17 At 46 is regular 13 17 IG „ 15 22 ,',' 21 „ 40 „ „ 47 „ „ 47 PILOCARPINE IN PUERPERAL ECLAMPSIA. By R. H. J. Fetherston, L.R.C.S.I., L. et L.M.K.Q.C.P.I., M.D. et CM. Edin. During my residence at the Women's Hospital, it has been my lot to witness some twenty cases of eclami)sia; and having tried several methods of treatment with varying success, I have determined to give a few particulars of the treatment from which the greatest amount of success has been derived, namely, by the hypodermic injection of pilo- carpine nitrate. Before going into the treatment, I shall briefly give an account of the cases, so that you may be better able to judge of the value of the results. There have been in all twenty-two cases attended in the PILOCARPINE IN PUERPERAL ECLAMPSIA. 709 hospital during uiy residence. Of these, twelve developed the convulsions in the hospital, the other ten being brought or sent there at various periods of the disease — three being moribmid on admission, and dying in a few hours. Unfortunately, the notes of two cases have been mislaid, so that I am only able to give the particulars of twenty. Of these, nine were married and eleven single women, their average age Toeing slightly over 24 years; the youngest was 17, and the oldest 44. Fifteen of them were })rimipanx3, and one woman had previously had eight normal confinements. As to their condition when admitted — Thirteen were of urtemic type, with well-marked axlema of face and legs ; two were apparently heahhy , the other five being simply noted as delicate. The urine, on testing with heat and nitric acid, was found in every case to contain large quantities of albumen. Labour as a rule was slow, but in three it was rapid and precipitate; and in two it was doubtful if labour began at all. Delivery was completed imaided in thirteen, forceps being used in three, while podalic version was performed in one, and the remaining three died before delivery. Eleven of the children were born alive, only one showing any signs of convulsions during the time they remained in the hospital. Coming to theeclampsic seizures — The fits began before labour in five, in five others during the first stage, four during the second, and two in the third, the remainder (four) developing the convulsions after the completion of labour. The attack terminated in four before delivery (three of these being at death), six upon the completion of labour, and the "remaining ten at intervals varying from an hour to 4i days after confinement. The average number of fits was thirteen, but this is by no means an accurate average, as in those who had convulsions on admission it was impossible to obtain the exact number of fits from wliich the}^ had sufiered. As to the mental condition^ — they, with four exceptions, became unconscious after a few fits, and remained so for several hours, in one case for 4^ days. The average maximum tem- peratui-e was I02'.o^ F., the pulse varying from 120 to 160 per minute, while the respirations ran as high as 44. The termination as to the mother was death in five out of twenty-two cases — three, as I have before mentioned, being moribund on admission. Treatment. — When possible, chloroform was given at the approach of each convulsion, and its administration continued for sufficient time to cause relaxation of the muscles. I may here mention that I found a very small quantitj' of the drug, if given in time, was sufficient to prevent the violent spasms. The bowels were well em])tied, croton oil being generally chosen from its rapid action, and the simplicity of its administration. In seven, venesection was performed, the amount of blood taken varving from twelve to twenty-four ounces ; and in three cases its beneficial effects was very marked, but in the others it seemed to exert little or no power in controlling the disease. Three patients bad morphia by the skin, in doses of a quarter or a half grain ; and in one a wet ])ack was used, without any ap})reciable result. After free purgation, enemas containing chloral hydrat. and potas. bromid., thirty grains aa, were given in eleven cases, being usually repeated every six hours ; and if pilocarpine was used in the same case, the two drugs were made to alternate. Before going on to the treatment with pilocarpine, 710 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. I may mention that I at fii'st gave it in all cases, but in two of them (feeble delicate women) rather alarming symptoms supervened, such as marked lividity with very feeble action of the heart, coma being pro- found, with considerable cBdema of the lungs ; so that I have now discontinued its use in feeble subjects, only administering it where the patient is strong, and often of ura^mic type (with short thick neck, puffy face and eyelids, and more or less anasarca of the lower extremities), has a full, rapid and incompressible pulse, the urine being at the same time usually dark and scanty, containing much albumen. It was in such subjects, more especially if met with early in the attack, that I have found benefit accrue from the administration of pilocarpine, whicli, if given under the skin and in full doses, usually acts in from three to four minutes, causing profuse diaphoresis, the perspira- tion pouring off the body, and drenching the patient's clothes. The pulse almost invariably slows down, and salivation is often very marked, flowing, if the patient is lying upon her back, down her throat, thus causing a loud gurgling noise at each respiratory effort. The force of the tits is considerably diminished, and at the same time they often become less frequent for two or three hours, when the effects gradually wear off, and in from four to six hours the perspiration will have completely stopped, the skin again becoming dry, and the injections will have to be repeated as long as the fits continue, or until any symptoms contra-indicating their use should appear, such as the pulse becoming very feeble, permanent lividity of the face and extremities, or any degree of oedema of the lungs, which complication is not uncommon after prolonged and violent attacks, even when pilocarpine has not been used. But since I have only used this drug in such subjects as previously described, I have never .seen it produce any symptoms to cause the least anxiety, though I have repeatedly given as much as three or four grains to one patient. Dose and Administration. — The dose that I have generally used has been one-half grain of the nitrate given hypodermically, repeated, if necessary, every six hours for three or four doses ; and then if required longer, I diminished the dose, finding that one-quarter to one-sixth of a grain was sufficient ; this I continued till the convulsions ceased, and until the return of consciousness; and in several. cases, I have kept up its admiiiistration after the return of consciousness in doses of one-tenth of a grain thrice daily for several days, thus keeping the skin moist, and so promoting the excretion of deleterious matter, and at the same time relieving the kidneys, which are usually in a state of disease. Care should be taken that the air of the room is warm, and that the patient is well and warmly covered during the sweating stage, for fear of lung trouble suitervening. In conclusion, I wish it to be understood that, while advocating the use of pilocarpine in certain cases, I do not consider that in it we possess a specific or a drug to supersede all others in the treatment of eclampsia, but wish to urge that in it we have, when used in suitable cases, a valuable adjunct to other more widely known and less dangerous drugs, such as chloral hydrate, potas. bromide, morphia, or chloroform. THE OBLIGATIONS OF GYNiECOLOGY TO OBSTETRICS. 711 THE OBLIGATIONS OF GYNECOLOGY TO OBSTETRICS. By Felix Meyer, M.B., B.S. If the title of this short essny slioulcl seem in any way equivocal, I would premise by saying that fur from being in the slightest degree a depreciation of a specialty tliat is daily receiving greater recognition as a legitimate application of a special surgery and therapeusis for the diseases peculiar to women, it is rather a special plea for a more scientitic development of a phenomenon which, originally universal in its naturalness, is nowadays too often unnatural, misunderstood, and in consequence, more or less — if I may use the term — mal-administrated ; or to come at once to the indictment, I would say, that unscientific obstetrics are a veiy large factor in the product of modern gynaecology. This opinion is based mainly on the experience gained by a residence of over four years as House Surgeon to the Women's Hospital, Melbourne, with an annual average accouchment of 600 women, an intirmary treating yearly some 350 gyntecological cases, and an average annual attendance of some 400 out-patients. Private practice has fully confirmed my views. My conclusions are : — (1) That single women enjoy a disproportionately larger innimnity from special disease than married women. (2) That a large proportion of manied women date their special trouble from confinement or miscarriage. (3) That in a large number of this latter class, it is the first confine- ment or miscarriage that is the starting point of the trouble. In making this estimate, I am not ignoring the fact that numbers of single women (and married women also), suffering from special disease, fail, from motives of delicacy, to present themselves for treatment ; that in others, independently of childljirth, there may be hereditary, congenital, or acquired disease ; and that incompatibility in marriage and general pathological conditions play a very important part ; but even after eliminating these causes, I maintain that there still remains an unduly large number of cases which have their first source in the obstetric function ; and it is the perversion of this function which I wish briefly to touch upon. The Period of Pregnancy. While it cannot be denied that any abnormal condition during pregnancy must discount the chances of a successful jDarturition, it is also true that such abnormal conditions are very often overlooked by, or unknown to, the medical man ; since, except in the case of some remarkaVjly disturbing element for which he may be summoned, he very often sees nothing of his patient between the time of his engagement and the onset of labour. Many of these abnormal conditions, especially in the case of first pregnancies, are accepted by their subjects as natural accom^^animents, and are allowed to continue with all their deteriorating effects up to the time of labour. Such, for example, are versions or flexions of the uterus, mal-positions of the child, leucorrhoea, blood discharges, and pathological conditions of the genital tract generally. Wliei'e, in 712 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. answer to questions, there is the slightest suspicion of the existence of anything abnormal, an examination should be insisted on, a little tact and delicacy on the part of the medical man generally overcoming the natural objection of a woman for the first time pregnant. I can only say that, by insisting on this method when deemed necessary, it has fallen to my lot to detect and treat beforehand complications that might have otherwise proved serious. The question of surgical interference during pregnancy is one that can be answered only by the individual exigency of the case. While it is true that women have miscarried after the drawing of a tooth, it is also true that grave operations, such as ovariotomy, have been performed without in any way disturbing pregnancy. I have done numerous small operations on pregnant women, with and without an anaesthetic, even to removing a cervical polypus, without any untoward result. Coming now to labour itself, we arrive -at a period during whicli unskilled obstetrics provide ample material for the gynaecologist. If labour with the human species were the almost purely physiological process it is with tlie lower animals, midwifery, as an art, would have no need of existence; and what is often sneeringly termed "old women's work " might be safely relegated to old women. The conditions of life, however, bring about so many deviations from the natural process, as to render it very often pathological ; and in this part of medical science more than in any other, I take it, does it lie within the function of the practitioner to bridge with the smallest span the distance between the natural and the unnatural. How this function is perverted, I wish briefly to indicate. The value of a rational antisepsis needs no comment from me. The enormous reduction of the mortality of lying-in hospitals over the whole world, since its introduction, speaks volumes. Grave, then, is the error of those accoucheurs and nurses — and their number is not few — who ignore it. I use the word "rational," because its employment is very often irrational and excessive. The First Stage of Labour. And here we come to the questio vexata of the clinical significance of lacerations of the cervix. And while I would not, as some do, ascribe all pathological conditions of uterus to this lesion, I venture to think that few will agree with even such an eminent authority as Noeggerath, wlio, basing his opinion on an examination of one hundred cases, declares tliat lacerations have no influence on the development of uterine affec- tions, either in regard to number or intensity. If wrong, I am content to err in the good company of almost the whole of the American gynsecologists, a large number of Continental ones, and latterly, not m few of the English specialists. And though statistics show that lacerations exist in some 30 per cent, of parous women, it does not follow that they do so rightly. It is sufficient for my purpose to state my l^elief, tliat lacerations of tlie cervix have an importance that extends beyond the time of their pro- duction ; that, in addition to tlie risks of haemorrhage and septicfemia at the time, they lead to exaggerated cell-growth (one form of which may be epithelioma), sub-involution, and chronic ceiwical endometritis. On these grounds alone, I advocate a greater care in the guarding of THE OBLIGATIONS OF GYNECOLOGY TO OBSTETRICS. 713 the cervix in the iiist stage than T believe at present obtains among accouclieurs. Its claims are surely equally as strong as those of its analogue — the well-cared-for perina-um. T do not for a moment forget tliat lacerations Avill and do occiu-, no matter what care is given, but I defend tlie position that they are largely preventible. Among the preventil)le causes is — Labour going on with a rigid os. In anaesthetics, in addition to other valuable results, we have the almost certain remedy of this complication. In connection with this part of the subject, I may mention a somewhat interesting case, so far as I know, unique : — I was called one morning at ten o'clock to see a lady in labour. She was the mother of live children, but had had no child for seven years, and some twelve months back had been the suljject of Emmet's operation. Pains were slight. She would permit of no examination. I cannot say I was very anxious as to the condition of the os, never having previously attended a woman who had had the operation. I received an urgent message in the night, and coming into the rooDi at the commencement of a strong pain, I examined and found the os small (the size of a threepenny piece), with a hard band of membrane occluding ; and as the pain proceeded, I felt the head of the child gradually tearing through the left lower part of the cervix — the hair of the child's head could be distinctly felt. Thei'e was no time to lose ; 1 poured a quantity of chloroform on to an inhaler and made the nurse apply it to tlie patient, and guiding a curved blunt-pointed bistoury along the riglit forefinger to the cervix, I slit through the cervix up to tlie margin of tlie laceration just produced by the head. Even then, as the pain continued, there was great difficulty in preventing the head from pushing upwards and enlarging tlie tear towards the fundus. The head had to be guided by two or three fingers over the cervix, as one would support a perina?um, but delivery was effected without anything worse than severe hemorrhage. The patient made a good recovery, and twelve days after, on examining, I found the laceration healed. I have since then had occasion to attend several women who have had this operation on the cervix (Emmet's), and with one exception — where I divided a cicatricial band in the beginning of labour — I have had no trouble. While it is in no way the province of this paper to deal with the treatment of lesions at a time remote from the period of parturition, during wliicli they may have been produced, I must — unless I have tliorouglily misunderstood one part of Dr. Batchelor's able and practical address of yesterday — beg to differ from his views as to the wisdom of ignoring the significance of extensive lacerations of the cervix, for T have yet to learn that such solutions of continuity are physiological ; and as for the few cases on which I have operated during only four years of private practice, I feel certain they would have been justified in the eyes of Dr. Batchelor, or any exponent of gynaecological or general surgery, as much from their abnormal appearance as from tlie relief of symptoms which followed operation. If in slavish subservience to a fad, some specialists attack every form of cervical eversion and small fissure with operation, it is the wrongful exponent of a system, not the system itself, which must be condemned. 714 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. However, when all is said and done, I think most will agree that we should try to prevent the tearing of the os in labour ; and so far as rigid OS is concerned, in my experience the value of anaesthetics (not necessarily deeply pushed), is beyond a doubt. Another cause of laceration of the cervix is the hasty and ill-advised use of forceps, either while the os is rigid — a not uncommon practice — or before it has had time to dilate — a still more common practice. In such cases, the instrument might well be termed pra^ceps. It may seem puerile to allvide to such a self-condemning practice, but I make bold to say it is such a common one, as needs allusion to in a paper like this, which is in the main suggestive. If the use of forceps is abused in the first stage, it is much more so in the second. The how and the when of their application cannot be tavight theoretically ; but this is certain, that to their misuse and unskilful application are due, very often, lacerations of perinseum, I'ectocele, cystocele, vesico-vaginal and recto-vaginal fistula, pelvic cellulitis and peritonitis — the latter very commonly the first link in a chain of pathological process, leading up to ovarian and tubal disease. Formidable as this list appears, it is a true bill ; and in taking the history of every woman who attended either as an in-patient or out- patient during my tei'm of residence at the Women's Hosj^ital, how often has the stereotyped reply come, " I have never been well since my first confinement ; I was hurt with instruments." I yield to none in my appreciation of the value of forceps, but in the hands of many, they are a thing of evil. Before leaving the subject, I may mention that: — (1) Before using forceps, I never omit to draw off" the urine, or make the patient pass it. (2) I invariably use an ansesthetic more or less deeply. (3) In most cases, I remove the blades before the head has passed the perinteum, in order to allow some gradual distension of the latter, and also to give the uterus some share in the expulsion of the child. Of the care of the perinfeum, as a necessity, I need not speak ; but I may mention that I now condemn what I at one time approved of, viz., the practice of pushing the head through the vagina by means of a finger or two in the rectum. Injury to the bowel or fistula may follow from this practice. It is far better to apply pressure at the space between tlie anus and the tip of the coccyx. I consider that all perineal teai's, unless there is some special contra-indication, should be at once brought togetlier with sutures ; good union is seldoni effected without ; no obstetrician, I would ventui'e to say, should be reproachable with the necessity of perinieorraphy. The mismanagement of the third stage of labour is responsible for not a little mischief to the uterus and appendages. On the best method, tliere still exists a great diversity of opinion ; but practically there are tvo schools — the advocates of Crede's method, and tliose who follow the expectant line of treatment. Dr. Felsenreich states, tliat out of 13,904 cases which occurred during four and a half years in Professor C. Braun's Clinic, Crede's nietliod succeeded pei-fectly well in all but fifty-one cases. In Munich Hospital, on the other liand, Winckel allows two hours to elapse before resorting to Crede's method. The two schools, howe^■er, are gradually approaching each other, tlu; ad\ocates of Crede's method inclining to THE OBLIGATIONS OP (JYX/KCOLOGY TO OBSTETRICS DISCUSSION. 715 lengthen the time before using expression, and the supporters of the expectant method shortening their period of expectancy. Personally, I have obtained the best results from Crede's method, and should be Very sorry to allow a placenta to remain in the vagina an hour, when the mildest of traction on the cord, or even the passage of a finger into the vagina, would suffice for innnediate delivery. Hasty and excessive manual pressure on the non-contracting or soft uterus is often followed by displacement, svib-involution, or an inflannnatory condition of the organ and jtarts adjacent. One important point in connection with the subject is that ergot should not he given during the placental stage. The amount of rest required by women in the puei'pei*al condition is, to my mind, greater than that usually insisted on by obstetricians. The average time required for involution is ten weeks, and when we regard the number of women who from choice, not necessity, are about and active in two to three weeks, resuming the pleasures and labours of life, we cannot be sui'prised at the consequent uterine troubles. It is abundantly proven, that involution is accomplished more slowly where haemorrhage has been an accompaniment of parturition, and also in the case of those who do not nurse — an argument whicli might well be made use of by medical men, in counteraction of the growing tendency, especially among the upper classes of women, to avoid the duties of nursing. Such is a crude and imperfect sketch of the prophylactic duties of obstetrics against secondary disease, and while it may contain nothing new or original, or nothing that may not be found scattered through the pages of a standard text work on midwifery, it may, as a purely clinical experience, serve as a reminder. There are medical men who get through a large midwifery practice year after year, in happy ignorance of the fact that many of their former patients are applying to sj^ecial hospitals, or specialists, for the relief of conditions directly traceable to parturition ; and, no doubt, the rank growth of self -constituted, ignorant, and unlicensed so-called midwives is contributing its quota to the sum of gyniecology. If obstetrics are worth doing at all, they ai-e worth doing well ; and, regarding every woman in the light of a " complex organism round a uterus," the maintenance of the uterus in a natural condition during the storm of parturition is a sine qua non in the preservation of the health of that organism. Dr. Chambers observed that the nature of diseases of women had changed much in the last twenty years. Formerly, we heard a great deal of vesico-vaginal iistulas, and very little of lacerations of the cervix. Nowadays, matters were very different. He thoroughly agreed with Dr. Meyer, that a confinement was often the starting point of a woman's trouble. We were in need of more careful accoucheurs and nurses. He was of opinion that laceration of the cervix interfered with involution of the uterus. Dr. Balls-Headlev believed that, in certain cases, disease of the uterus and appendages was due to parturition. He made it a point in his pi-actice to enquire if forceps and chloroform were used in the confinement. He looked upon lacerations (a subject, by-the-bye, some- what out of the scope of the paper) of the cervix as a wise provision of 716 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Nature for the prevention of too many cliilclren. He thought they were very often due to the head coming through a rigid os. He was one of those who believed in tlieir importance as a cause of disease. They brought about a slowing of involution, retroflexion, and jjrolapse. Dr. Jakins agreed with Dr. Meyer, and would go beyond him, especially in the use of antesthetics, which, more frequently employed, would prevent many grave accidents. [At this point, Dr. Batchelor asked permission to interrupt Dr, Jakins, with the object of saving the time of the meeting, as he perceived some remarks he had made had been misunderstood; and although only too pleased to discuss real difficulties, he did not wish to waste time with shadows. As a matter of fact, the opinions he held seemed to be unanimously held by members, viz., that cases of lacei'ation, requiring operation, were without doubt occasionally met with; but the condition was by no means so common as to class it among one of the common diseases of women causing severe and constant symptoms; and, for his own part, he considered the discoveries of Emmet immensely less important than the discoveries of Tait. With all due deference to his friend. Dr. Balls-Headley, whose experiences he most readily admitted were larger and wider than his own, he had formed an opinion diametrically 0]iposed to him on this subject. He had never seen, heard of, or imagined it possible, that a case requiring trachelorraphy could occur in a single girl, except the laceration resulted from a previous jDregnancy, or operative measure.] Dr. Jakins continued, that a great many cases of laceration could be cured without operation, and that there were many in which the laceration healed spontaneously. With regard to the third stage of laboui', he removed the placenta almost immediately, by passing a couple of fingers into the uterus. Dr. WoRRALL differed from Dr. Meyer as to forceps being a cause of lacerations ; he used forceps once in every six cases. The use of forceps for contracted ]3elvis was rare in New South Wales. If laceration were produced, it was preferable to vesico-vaginal fistula. He differed altogether from Dr. Jakins' method in the third stage. He thought that no man should insert his hand into the uterus after delivery, except in cases of adherent ])lacenta. So far as the treatment of lacerations was concerned, he did not believe in a cure of the laceration. The operation was to take a wedge-shaped jiiece from the cervix, a process which lightened it, and otherwise improved it. Dr. Adam agreed with Dr. Meyer. As regarded lacerations, there were no doubt many cases of granular os which healed under the action of chemicals; but he would ask — Why not do a simple surgical operation, which removed unhealthy surfaces "? Dr. Foreman did not agree with Dr. Balls-Headley, that lacerations of the cervix put an end to pregnancy. He thought they rather favoured it. He met with a great many cases of laceration. If the surfaces were covered by healthy membrane, he left them alone ; if there were ectropion, he o]ierated. The best proof of the value of the operation was the result to the patient — comfort, and loss of symptoms ; and moreover, there was no danger in the o])eration. Dr. Batchelor congratulated the Secretary on his paper. He thought tliat slitting up the os by bistoury, as Dr. Meyer had done, was not done ELECTlilCITV IN' DISKASES OF WOMEN. 717 often enougli. If we did not take Nature's hint, plain enough in Dr. Meyer's case, rupture of uterus would follow. He believed that iu a case of eclampsia which he saw, cutting of the cervix done early would have saved life. He quite agreed with Dr. INIeyer as to the abuse of forceps. He objected to Dr. Jakins' introduction of the hand in the third stage of labour. A})art from other objections, such a proceeding (as Dr. "NVorrall noticed), favoured the introduction of bad air into the passages. He knew another pi-actitioner who followed Dr. Jakins' method, and who had had no bad results, but he should be sorry to adopt it. He had done Emmet's operation, and did not agree with Dr. Foreman as to its non- dangerous nature. Dr. Meyer, in reply, was pleased to find that practically all the members agreed with him. Dr. Balls-Headley was perhai^s right in saying that the subject of lacerations was hardly within the scope of the paper, and he must admit that he had introduced the subject after hearing the President's address, in order to cause a discussion on the subject, as there were evidently differences of opinion. As regards forceps, he begged to inform Dr. Worrall that his average was almost as great as Dr. Worrall's (1 in 6); still he maintained that, to save time, etc., they were abused. Dr. Balls-Headley 's idea, that lacerations of the cervix were a jirovision of Nature against too frequent preg- nancies (combatted by Dr. Foreman), was oj)posed to the experience of Noeggerath, who thoiight that women with lacerated cervices conceived uiore readily than those with the cervix intact. He could not agree with the Qiethod of Dr. Jakins in the third sta^e of labour. ELECTRICITY IN DISEASES OF WOMEN. By J. Foreman, M.R.C.S. Obstetric Surgeon, Prince Alfred Hospital, Sydnej'. This subject is one that has exercised the medical mind to a great extent lately, owing to its re-introduction by Apostoli, who has recorded a marvellous succe.ss, certified to by sevei'al leading men in England. One could not hear of a method which promised .so much to the unfortunate patients and to the practitioner, on account of its harmlessness, without being desirous of trying it. Accordingly, I had 100 Leclanche cells fitted up in my rooms, and I got the instruments, such as are used by Apostoli, from Paris. At the same time, a large battery similar to mine was fitted vip at the Prince Alfred Hospital, where every facility is always given by the directors for investigation. The principal use for this treatment was for tibroids, and so much has been written about it in the medical journals that I need not take up your time with details. The instruments and the modes of applica- tion wei'e as described by Apostoli, namely, a ]>latinum sound introduced into the uterus and guarded by a vulcanite canula in the vagina, and on the abdomen a lai^ge soft clay pad, with a large zinc plate on it. The 718 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. galvanouieter at the Prince Alfred Hospital was a very elaborate and ingenious one made by Professor Threlfall ; mine was Apostoli's, which corresponded exactly with the former. The strength of the current varied from 50 to 300, the latter always under chloroform. The number of fibroids operated on by this method was ten. Without going into particulars, which would not be instructive but only wearisome, I will sum up the results, which were disappointing in the extreme. In some of the cases whei'e there was pain, ease was certainly given, but in no case was there a diminution in the size of the tumour, nor was there a decrease in the amount of haemorrhage which could not be produced by other means. In one case where she had had forty applications, I gave a current of 350, and some sloughing and high temperature resulted. In another, with the same current, death ensued. The treatment lasted from six to twelve months, and the applications were generally twice a week when well. My experience, you see, has not been a happy one, and I cannot understand a man like Dr. Keith writing as he does about it. It was mainly due to reading his ai'ticles that I persevered, for praise for the system comes with great weight from one who has been the most successful in removing these tumours. I could not see any fault in my way of applying it. The sound was always carefully passed, and generally without pain, the pad was lax'ge, and the current strong enough, and plenty of time given, both in the gradual increase of the current, and the time the patient was under it. At any rate, it has not come up to the expectations I had formed and hoped for. I can now speak of cases where it has been of benefit. In cases of endometritis, where there is a thick viscid mucus so difficult to get away, applications two or three times a week will prove of great use ; but even here it is far inferior to curetting, both in point of time and for certainty of cure. Cases of chronic metritis are relieved of pain to a great extent, but it is a curious thing that the improvement lasts only for about forty-eight hours. It otherwise exerts no influence on the tissue of the uterus. The cases I have been perfectly satisfied with are those where there has been an enlarged ovary, bound down and very difficult to remove by abdominal section ; in fact, I look on it as the most difficult opera- tion there is. The first of these cases was on the left side ; the swelling about the size of a hen's egg, very fixed, and containing a little fluid. It was very painful, and caused so much discomfort that removal was necessary. Under chlorofomn, it was pierced by this lance-pointed stilette for about half an inch, and a positive current of 150 milliamperes given for ten minutes. No reaction after, and there was such a marked decrease on examination four days later, that it was repeated. She left the hospital perfectly well in a fortnight, with scarcely a trace of the enlargement. The second was more instructive, as the growth was solid, and about the same size as the former. A large sized aspirator was used in all dii-ections without a trace of fluid. Three applications were used in this case, with a result l^etter than the formei', if possible. The third case was one where the appendages had been matted together from inflammation, and the pain was intense; two applications were made, with perfect relief, and subsidence of enlargement. I have ELECTRICITY I\ DISEASES OP WOMEN — DISCUSSION. 719 seen this patient twelve months after, and on examination there is notliing abnormal to be felt, and she says she is in perfect health. The second wrote to say she had no complaints after eight months, and the Hrst Avould have presented herself again had there been any cause. This, to put it shortly, has been my experience in electricity. The number of cases of metritis and endometritis has been considerable; the major troubles are given as they occurred. I have not wearied you with details, because, at a meeting like this, most of you are as well, if not better, acquainted with the subject than myself, and one should give his experience, and not wander off into comparative trifles, which every one should be acquainted with. I am sorry I cannot say with Keith, that the knife will never be required for fibroids. T occasionally do a hysterectomy, and have no cause to be ashamed of my success; but no one would hail with greater pleasure any means, such as I thought this would be, that would give us a safe and bloodless cure. Dr. Rowan said that he was personally obliged to Dr. Foreman for his paper. In his own case, he had had good experience of the method. He had made himself acquainted with the details, and had read carefully Apostoli and Keith. Having a complete apparatus, he had applied this form of treatment to fifteen cases in his own private hospital, and like Dr. Foreman, he was sadly disappointed. He must, however, except the application to cases of menorrhagia, whei-e he had great results, but on the cessation of the application, there was a recurrence of the old trouble. He never used more than 250 milliamjjeres. He found alarming symptoms follow on exceeding this dose. He thought that the tenderness and pain over the ovary, extending to the groin, which sometimes ensued, was due to the ovei'-stimulation of the nerves. He had applied the method in acute pelvic cellulitis, without good result."!. In answer to a question of Dr. Balls-Headley, he (Dr. Rowan) said that he had passed the sound into the cavity of the uterus in uterine thickenings, and afterwards used the stilette and punctured the wall all round. Dr. WoRRALL observed that what struck him in this new method was its great seriousness. The necessity for chloroform rendered this iorm •of treatment largely impracticable. He thought that metrorrhagia was more easily treated by curette. Dr. Jakins could speak of this method from his private practice, and not favourably. Apostoli had reported no cures, merely improvements. Dr. Balls-Headley remarked that, though it might be said " fibroids did not kill," yet they often broke down, and wore patients •out, causing anasarca, ikc. Dr. Foreman's method of applying electricity was new to him. He had seen Apostoli at work, and was not at all impressed. According to him, two or three applications not exceeding two hundred and fifty milliampei'es sufficed. Moreover, Apostoli's diagnoses were not so definite as one would expect. He had seen ■women in London hospitals carefully treated for fibroids after this method, and their temperatures had gone up to 102''. In brief, he had not had much reason to be pleased with this iorm. of treatment. Dr. Batchelor thanked Dr. Foreman for his paper on a wide and important subject, and his special case was an example to us to bring forward bad as well as good results. He was not surprised, however, 720 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. at Dr, Foreman's results. His own experience was too small for a decided opinion on his part, but he must say that Dr. Foreman had missed the essential element in Apostoli's treatment, viz., accurate domqe. He would point out that "seventy or eighty cells" meant nothino- definite, for if one cell liappened to be defective, all below were impaired, and the result might be a weaker current than with only twenty cells. Dr. Foreman had used large batteries ; Keith used a twenty-five Leclanche. Gaiffe, of Paris, used circular carbons, witli a small internal resistance, of twenty-four cells. Treatment was quite possible with an ordinary thirty-cell Stohrer battery, with a strong liichromate solution. Then there was a difference of galvanometers. He (Dr. Batchelor) had all his apparatus made in Dunedin, using a bichromate solution, aii ordinary galvanoscope, graduated by a tangent galvanometer, giving accurate readings. With a Stohrer's battery in good order, and with a fresh solution, he had obtained 200 to 240 milliamperes, with an extreme resistance of 170 ohms, which from numerous observations he believed to be the average resistance between the uterus and the abdominal walls. He was convinced that the local effects of the current were those of a strong chemical cautery, with decomposition at the site of the poles. On one occasion, through deficiency of the external rheophore, he caused a severe burn — resulting in a slough which took a month to heal ; this, too, in a current of only eighty milliamperes. Where there is less resistance and a far more concentrated current, we have only to expect much greater effects. On the whole, he believed this method to be a convenient form of cautery. He had, under three months of this treatment, reduced to below the umbilicus a tumour originally extending to the ribs — half an inch above the lowest rib on the right side, and one and a half inches above the corresponding left rib. Although Apostoli might be an enthusiast, and, like himself (the President) in regard to his views on "tubes," extreme, yet we could not possibly ignore statements coming from men like Keith, who had given up hysterectomy. He would point out to Dr. Rowan that he had applied the constant current to an acute inflammatory condition. This was quite opposed to Apostoli, who had recommended the Faradaic form until the subsidence of the inflamma- tion. It was quite possible, in such cases, that length of time sufficed for a cure. Dr. FoREJiAN, in re})ly, said that the only good he saw in the method was in its local action. In old inflammatory exudations, his experience differed from that of Dr. Batchelor ; nevertheless, he would try the method. Dr. Worrall's objection, on the score of chloroform being a necessity, he thought could not have much weight. With regard to the remarks of Dr. Balls-Headley, he agreed that cases of fibroids did end fatally. He had seen a large number of such cases. He remembered however one case of a lady, the subject of a large fibroid, living in unhappy circumstances, and wishing for death. She was greatly lowered by ha.'morrhages, till her skin became like parchment. Death was daily exj)ected. He kept her in bed for months, and she was now absolutely well. With regard to dosage, he could tell Dr. Batchelor that he measured his doses with the galvanometer to the extent it permitted. SECTION FOB DISEASES OP THE EYE, EAR & THEOAT. PRESIDENT'S ADDRESS. By Mark Johnston Symons, M.D., Ch. M. Edin. Lecturer on Ophthalmic Surgery to the Adelaide University. Hon. Ophthalmic Surgeon to the Adelaide Hospital. Gentlemen, — My occupancy of the position of President of the Section for Diseases of the Eye, Ear and Throat, I feel to be a very high, but unearned honour ; and my feeling of gratitude to the organisers of this great Congress is all the deeper, from the knowledge that I am so little entitled to it. I cannot be insensible of the fact, which I freely admit, that rather than to myself, it is to the colony from which I hail, that I owe my selection to this position — the colony in which I am proud to be able to say the idea of an Intercolonial Medical Congress had its inception, the able carrying out of which gave to us the first of what I hope, and indeed may prophesy, will prove to be a long and successful series of these invaluable meetings. At the first meeting of the Intercolonial Medical Congress, the Sections were four in number — Surgery, Medicine, Gynaecology, and State Medicine ; there was no division set apart for the subjects included in this Section, Doubtless we have, in most great undertakings, to creep before we run ; but the leap to the dignity of a Section, which has been made here by special subjects, is a matter for congratulation to all of us generally, and especially to those of iis who devote our time and thoughts to any or all of the subjects embraced in this Section. The separation of the organs concerned in the three senses of seeing, hearing, and speaking, from general Surgery into a Section of this Congress, leads us to consider this severance, and the existence of specialism in our midst. It is well known that there are many of our profession who regard the existence of specialism with grave doubts as to its justification ; and that its rapid growth in recent years has the more or less silent disapproval of many of our brethren, who are leaders of thought amongst us, whose breadth of idea generally is beyond question, but who still look with alarm at the spread of specialism which is becoming visible in all directions, lest its votaries become narrowed in their knowledge of or interest in disease by the limitation of their work. 2a 722 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. A glance at the history of Surgery shows us that every medical practitioner was a specialist in early times. Herodotus tells us that the healing art in Egypt was subdivided into many specialties in his day — *' Here, each physician applies himself to one disease only, and not more ; all places abound in physicians — some for the eyes, others for the head, others for the teeth, «fec." Celsus showed predilections for the eye and ear. We find him writing on tumours of the eyelids, pterygium, symblepharon, staphyloma, and on cataract (where he describes the operation of inferior kei-atotomy), and also "the modes of repairing defects of the ear." Antyllus, in the first century, affected throat work, and is supposed to be the first who recommended bronchiotomy in inflammations attended with tumefaction, which threatened suffocation- In the eleventh century, Albucasis, in advocating the operation of depression for cataract, mentions that he had heard of a certain oculist who sucked out the cataract through a small tube. In a lesser degree, specialism prevailed throughout the middle ages ; but apparently they did not as a rule become specialists in the ordinary course, but rather acquired what knowledge of general principles they possessed as a result of studying the particular branch in which they professed to be proficient. This kind of specialist exists now in the form of what are colloquially termed " quacks," and we have a variety of them in the Australian colonies. They affect chiefly a special know- ledge of the subjects comprised in this section ; and from the results of their practices, we may gather the unfortunate condition of the patients of many of those specialists who practised in bygone ages, assisted chiefly by rule of thumb and magic nostrums. This specialism of the ancients can hardly be compared with the specialism of to-day. In the Legal profession, specialism abounds — some devote themselves entirely to the Law of Probate, others to Divox-ce, to the Admiralty, or to the Ecclesiastical Coiirts. In Engineering, specialism is most marked in the divisions of civil and mechanical, with the subdivisions of sanitary, mining, hydraulic, electrical, &c., &c. But specialism in Medicine is as little comparable to specialism in Law or Engineering, as is the human organism to an Act of Parliament, as the study of the living to the study of the inert. The term " specialism " is faulty, as conveying the idea of work done in an unusual manner; while the definition of our work should be the exercise of an expert knowledge of the diseases of a naturally defined oi'gan of the body. Specialism immediately takes its rise from the common fact, that attention can be better directed upon a special object than upon a group of objects, particularly when such special object has an inherent interest for the observer; whereas things in which we take only a general president's address — EYE, EAR AND THROAT SECTION. 723 interest are " seen, ratlier than distinguished." In Medicine, specialism has an interest whicli can be felt in no other profession. The wondroiis structure of the organs concerned in the special senses, the beauty of their architectural design, the marvellous perfection of their adaptation to the purposes of life, the inaccessibility of their mechanism to ordinary observation, all tend to create a taste for the study of one or more of these organs in health, a longing for an acquaintance with their diseases, and a desire to master the details of their rational treatment. Moreover, there is an absorbing satisfaction in watching their return to health and usefulness. The fascination felt in his work by a specialist increases with his opportunities of observation, the origin and nurture of which may be ofttimes traced to a personal defect, claiming his greater sympathy. He becomes accustomed to the technique of examination, to a high appreciation of the value of the organ with which he has special concern, and to a desire to benefit his fellow sufl'ei'ers, which is dis- associated from mundane calculations. It is with a feeling of j)ride that he finds himself, after years of general work, accepted as a specialist ; able to devote all his time and all his thoughts to that one part of the enormous field in which he labours, but with the knowledge that his own field of study is still very large. It is then that he may be excused the neglect of other parts, to leave unhampered the pursuance of an intimacy with a part of Surgery, where special methods of observation, or special manipulative or operative dexterity, is required. , Specialism in medicine is the natural outcome of progress in medical science ; and, as in every other branch of science, there is a continuous progression from the general to the special ; were it not so, retrogression would be implied, which is practically impossible. The progression is in fact the operation of a natural law, and all we can consider is not whether specialism in medicine is desirable, but whether it is advisable to assi.st the progression as far as lies in our power by artificial means. Are we to assist the acquiring of special knowledge, by sacrificing to some extent the study of general principles ; or are we to continue to recognise in our colleges and universities a general know- ledge only, and allow specialism to mark out its own course ? In attempting to find an answer to this question, I think it may be taken for granted that, under any circumstances, the few years of study at present prescribed for intending followers of our profession are none too long in which to obtain such general instruction as it is absolutely necessary a specialist in any branch should have. If we wish to assist specialism, v,e must confine ourselves to individual exertion — firstly, in following the natural bent of our inclination (if we have one) in taking up the special study of any particular branch of medicine ; and secondly, ^n practically recognising the status of brother specialists in their 2a 2 724 IXTERCOLONIAL MEDICAL COXGRESS OF AUSTRALASIA. particular line. This latter is already done to a large extent ; and so far as I can gather, its only effects have been the benefit of the public and the advantage of the profession, the status of the members of which must naturally be improved thei-eby. Specialism is welcomed by the general practitioner, who can at any time obtain the aid of one presumably more familiar with certain diseases, probably of rare occurrence, without the suspicion that such action may cause the loss — as patients and as private friends — of the sulferer, his family, and probably some of his acquaintances. I do not know that an 0])position to specialism exists among the profession in this continent ; but I certainly think that he who is true and just to himself, and honourable in his dealings with others, and who can prove an expert knowledge of certain branches of his profession, need never apprehend being proscribed by his fellows, but may expect the support and co-operation of the busy practitioner, who cannot spare the time for the purpose of making himself as familiar with those details of departments of our work which create the specialist, or the time for the working out of the details which the proper examination of special cases requires. The importance of diseases of special organs has been direly neglected in our teaching centres — a fact which entails an after-application, the realisation of which is a question of opportunity, rather than of desire. The growth of specialism in the future will be regulated only by a better attention to the teaching of these important subjects in the curriculum. This limitation of practice is a recent departure, born of the extent and complexity of medical knowledge in its entirety, of the whole of which no one can claim to have an equal grasp ; and the enormous bibliography of the present time will sanction, if not compel, a limitation of correct study. Thus we find the reason for the existence of specialists, in that no one can expect to be cm coiirant with all branches of medicine and surgery. The argument resolves itself into one of the external influences surrounding one's medical life, rather than an aim on the part of the specialist to separate himself from the work of his brethren. We have only to look at the pressure of work carried on by the many special hospitals, at the good these hospitals have done and are doing, and at the success of the special societies, to recognise that specialism has done much to relieve former apathy, to realise the fact that th& specialist has the confidence of the public, and to demonstrate that he is accepted by his fellows. To weigh the lasting benefit done by specialists to our craft, we have only to recall the names of such lights in the science of Ophthalmology as Mackenzie, Bowman, Graefe, and Donders; iu the science of Otology, as Cleland, Toynbee, Wylde, and Politzer j in the science of Laryngology, as Tobold, Voltolini, Czermak and Turck f ON CONVERGENCE. 725 the bare mentioning of whose names, without alluding to their many illustrious colleagues, would answer the deci-ying note levelled against true specialism from whatever source. Can the present, or will the coming generation of practitioners ever rei)ay the si)ecialist for the boon of the post-graduate classes, created by specialists and maintained by themselves. They are the outcome of the specialist's self-sacrificing love of his profession. That specialism is beneficial to the general good, I do not doubt; that it may be carried over far, I do not gainsay. The great drawback to specialism lies in the limitation of the field, which renders possible the existence of those pretending adventurers, who find adverse criticism less fraught with the risk of exposure, in proi)ortion to the smallness of compass of the subject with which they pretend to deal, and so the moi'e easily deceive an over- readily gullible public ; but these pretenders would soon cease to exist, as parasites in a noble profession, and as a fraud on an unguarded public, were the words written by Rhazes in the ninth century applied by the sutiferer of the nineteenth century in the selection of a medical attendant — " Study carefully the antecedents of the man to whose care you propose confiding all you have most dear in the world ; that is to say, your health, your life, and the health and lives of your wife and your children." ON CONVERGENCE. By Mark Johnston Symons, M.D., Ch. M. Edin. Lecturer on Ophthalmic Surgery at the Adelaide University. Hon. Ophthalmic Surgeon to the Adelaide Hospital. The study of convergence is at once interesting, intricate, and incomplete. A knowledge of it is essential to those of us whose aim it is to enable our fellow creatures to obtain, or retain, for their highest sense its greatest benefit, namely, perfect vision with absolute comfort. Good sight with comfort, in the possessor of two healthy eyes, depends tipon the absence of any defect of static and dynamic refraction ; and it is our duty to correct dynamic as carefully as static refractive defects, if we would do justice to our patients and to ourselves. The subject is still in its infancy, and in the belief that every contribution thereto may be useful, I bring before you, for your consideration, a few notes bearing practically upon that matter. Convergence may be simply defined to be the inclination of the visual lines meeting at the point of fixation ; or in other words, the vertical angle of a triangle, of which the eyes form the extremities of the base, and the })oint of fixation the vertex ; which point will lie within infinity, or not more than twenty feet from the observer. For, suj)posing tlie point to be beyond this limit, the inclination of the visual lines is so f26 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. minute as practicably to be unappreciable, and therefore we say that, for points outside this limit, tlie visual lines are parallel. This inclination is given to the eyeballs by means of the internal recti muscles. The horopter is a curved line along which the two eyes can join in sight, the two eyes initiating a balance at infinity, and governed for points within infinity by the instinctive muscular consent in which the muscles of adduction are harmoniously associated with the muscles of accommoda- tion of both eyes. The law which governs the extra-ocular muscles is, that the fovea centralis retina3 of each eye must be directed upon the object obsei'ved. This law, in conjunction with obedience to the law of accommodation, results in an object at the point of fixation being seen as a single clearly defined object, and binocular vision is then said to exist. It is recognised that an intimate relation exists between the con- traction of the ciliary muscle and of the internal recti ; between accommodation and convergence. This synergy necessitates the admission of a common centre of innervation. True binocular vision is absent in very young infants, being attained with the functional development of the brain, from which arises the capacity of receiving the image upon associated percipient points — the great essential of binocular vision. In some subjects, this capacity is never attained ; in others, it may be lost after having been presumably acquired. The absence of exact binocular vision is frequently unremarked by the subject, and varies from an unconscious lack to the inconsequential orbital i-ollings of cerebral under-development, as typified in young infants. It has been seen, that good vision depends upon accommodation and con- vergence being harmoniously exerted. Of these two, the accommodation depends upon the elasticity of the lens, and the proper action of the ciliary muscle, and, in the absence of disease or functional upsettings, varies little in different individuals of similar age, but gradually lessens from youtli to old age; whilst convergence, on the other hand, varies in persons irrespective of age, depending as it does upon the sufficiency of the muscles. To the latter, consequently, we will devote our attention. In regarding the behaviour of the internal recti muscles, we must take into account the resistance of the external recti, and both with their bearing upon binocular vision. We are taught several methods by which muscular insufficiency can be gauged : — First method. — Instruct the patient to fix a point, such as the tip of the finger, at thirty centimetres distant from the eyes; cover one eye, to conceal the object of fixation. If the eye from which the object of fixation is cut off maintains its direction, the muscles are normal in power; if it deviates outwards the internal muscles, and if inwards the external muscles are insufficient. Second method. — Place a prism with its base upwards before one eye, say the left, and direct the patient to gaze at a card, upon which is drawn a vertical straight line having a dot at its centre, placed at reading distance. The prism causes vertical dii)lopia, and prevents binocular vision. Two dots will be seen; if seen on the same vertical line, the muscles are said to he competent. If two lines, having a dot upon each, be seen, insufficiency of the muscles is proclaimed. Should ON CONVERGENCE. 727 the upper dot, which belongs to the eye having the prism in front of it, be seen to the right, i.e., crossed vertical di])lopia, tliere is said to be insufficiency of tlie internal recti. Should the upper dot be seen to the left of the lower dot, i.e., homouj^mous vertical diplopia, there is said to be insufficiency of the external recti, and that the prism placed horizontally, which will bring the upper dot directly above the lower, is the measure of the insufficiency. Third method. — Place a prism of 5° base upwards before one eye, say the left, and a red glass before the right eye. Direct the patient to fix a lighted candle at twenty feet. Two flames will be seen; the red flame of the right eye will be seen on a higher level than the uncoloured flame of the left eye. Should the red flame stand directly above the other, there is said to be equilibrium of the muscles. If the red is to the right — homonymous diplopia — we have insufficiency of abduction ; and if to the left — crossed diplopia — we have insufficiency of adduction. The prism placed horizontally, which brings the images vertical, is the measure of the insufficiency. Fourth method. — To measure the capacity of the muscles at twenty feet, place a series of weak prisms with the base inwards. The prism inmiediately below the one which causes diplopia marks the measure of the abductive power, the adductive power being similarly measured by .stronger prisms placed, base outwards, before the eyes. These methods are found in all standard works on the Eye. Landolt, in his book on " Refraction and Accommodation of the Eye," teaches : — Page 333. — " In order to fuse distinct impressions of each eye in single binocular stereoscopic vision, the degree of convei'gence required by the position of the object must be made to agree with the degree of accommodation which corresponds to the ametropia." Page 342.—" Two-thirds of the convergence niust be held in reserve, in order that one may work with the remaining one-third." Page 344. — "The further away the object is, the less convergence is required for its binocular perception." Page 352. — "Notwithstanding their greater mobility, hyperopic eyes do not attain a range of convergence markedly higher than that of emmetropes." Page 354. — " We know that the two functions are associated in such a way that, for a given degree of convergence, there is always a nearly equal degree of accommodation, and vice vend." Page 422. — "Not taking into account the distance between the eyes, convergence depends, for all eyes, solely upon the distance of the object." Page 491. — " Knowing the great amount of convergence required for work, it will not astonish us to find this function so often in default in myopes." Page 502. — " We must confess that our knowledge as regards mus- cular asthenopia and insufficiency of convergence is still in its infancy, losufficiency of the power of convergence is quite a widespread affection, and a frequent cau.se of asthenopia. It is not by any means peculiar to myopes only. Whilst great advantage is gained by Graefe's test (Method II), it is not true that the latent insufficiency is always brought thus to view." 728 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Noyes writes, page 85 : — "This power and abduction beyond parallel- ism reaches to a prism of from three to eight degrees in most people, while adduction for distant objects, say at twenty feet, extends to twenty or to fifty degrees, and for the average of persons who have not cultivated their power, it is about twenty-five degrees. If an object come near, adduction increases ra])idly, being aided by association with accommodation." Page 87. — "The most frequent cause of these troubles is error of refraction ; and in a general way, weakness of adduction goes with myopia, and weakness of abduction goes with hyperopia. Many excep- tions are, however, noted." Page 91. — "The most common error (muscular abnormalities) is insufficiency of the internal recti. This is most often associated with myopia, but with nearly equal frequency is found in emmetropia, and sometimes, too, with hyperopia." Page 93. — " But we must sometimes order prisms for permanent wear, either with or without i-efractive correction, and this is indicated when a muscular error has been detected in testing for the distance of twenty feet." Williams, page 328. — " Relative divergent strabismus may occur in high degrees of luyopia where convergence is impossible, or it may also be due to insufficiency of the internal recti, without myopia — the eye deviating outwards when the internus is fatigued." The necessity for bringing small things very near to myopic eyes, and thus demanding of the interni excessive strain in convergence, is partially provided for by a greater muscular development ; but it is a very frequent cause of insufficiency. For infinity, the optic axes remain parallel ; but for near vision, the internal recti act in harmony with the ciliary muscles of the two eyes, and produce a degree of convergence, corresponding to a certain extent with the focal adjustment. In Carter and Frost, chapter on Insufficiency, we are taught that: — " The relative power of the ocular muscles is of much greater importance than their actual power." jMeyer tells us that : — " Weakness of the internal recti may be observed either in hyperopic, emmetropic, or myopic eyes. It is however most annoying to persons having the last, a.s they are obliged to bring objects very close to them ; they must make their eyes converge for very short distances. We will now proceed to analyse 150 cases, in which measurements of the abduction and adduction have been made by the method of the vertically displaced images (Methods II and III) ; and 200 additional cases, in which the abduction and adduction at distance have been measured by horizontally-placed prisms. In all of these cases, the refraction has been noted under the divisions of emmetropia, when the refraction did not amount to over + 1 D or — 0"50 D, the remaining cases coming under the head of ]iyperoj)ia or myopia. The ])resence or absence of binocular vision is also notfid. The cases are collected fx-om refraction cases, avoiding any in which there was strabismus, or in which the vision was in any way interfered with by disease or injury. The 150 cases were tested by the first method, that is, by covering one eye after fixation at thirty centimetres, and in each case there was ON CONVERGENCE. 729 divergence of the exoliuled eye, irrespective of the refraction or measure- ment of the muscular state by any of the other metliods. Table I. Talk of 150 Cases tested hi/ means of Vertical and Horizontal Prisms : — Emmetropic . . . . . . . . 64 cases Hypeiopic . . . . • . . . 68 ,, Myopic . . . . . . . . . • 18 „ Total 150 „ ,j.^ p (Abduction = 962°; average, 6-128 ^^" ^^^^^ (Adduction = 1717°; „ 11-446 Vision at Reading Distance. Homonymous diplopia, Crossed ,, Balance . . 12 cases = 124 ,, = 56°, = 733°, = = 0-373 each -- 4-888 „ Vision at Twenty Feet. Homonymous diplopia Crossed ,, Balance . . — 54 cases = 43 „ = 53 ,, = 144' ^ 96° = -94 each = -64 „ Emmetro^jia . . Abduction- Adduction -64 cases. 392° = 791" = 6-125 each 12-359 „ Hypermetropia . . Abduction- Adduction —68 cases. 470" = 727° = 6-911 each 10-691 „ Myopia . . . . Abduction Adduction - 18 cases. 100° = 199" = 5-505 each 11-105 „ 116 binocular vision . Abduction Adduction —each 6-991 13-534 34 not binocular vision. . . Abduction Adduction — each 4-212 4-545 The cases in this table show that, in testing for the muscular state at reading distance, instead of balance there was heteronymous diplopia on an average equal to a prism of 4°, and at twenty feet there was homonymous diplopia on an average equal to a prism of J° ; and that the average abductive power at twenty feet is equal to a prism of about 6", and the adductive power to a prism of about 12°; the emmetropes most nearly approaching these measurements, while the hypermetropes have a larger measure of abduction, and a lesser measure of adduction, than the myopes. Those possessing binocular vision give a greater measure of both abduction and adduction than the average of the whole, while those not ))ossessing binocular vision have their measure of abduction and adduction so much alike as only to leave a small fraction between the two. Absence of binocular vision occurred in thirty-four cases, each of which had the measuie of abduction so closely reaching that of adduction as to amount to within a range of 2° prism on either side of the adduction ; and in all the cases where the abduction was either over two degrees greater or less than the adduction, binocular vision existed. 730 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Table II. Table of 200 Cases, in ivhich the Measurevient of the Muscular State was taken at Twenty feet, by means of Horizontally -'placed Prisms, in which the Refraction was dealt tvith as p7'eviously indicated, and the presence or absence of Binocidar Vision noted : — Average Measurement. 200 cases Myopia Hyperopia . . Emmetropia Having Binocular Vision, . Mj'opia Hyperopia . . Emmetropia Not having Binocular Vision Myoi^ia Hyperopia . . Emmetropia 12-280 19-066 12-914 9-448 7-650 8-428 8-416 6-750 Table III. 350 Cases.— Abduction, 5-920 ; Adduction, 11-136. Table III is composed of the cases in Table I and Table II, measured at twenty feet by horizontally-placed prisms. Table IV. Table of Forty Cases, in ivhich the Measurement of Adduction at Tiventy Feet is compared ivith the Maximum of Convergence in Metre Angles : — Adduction. Metre Angles. Adduction. Metre Angles. 9 16 31 20 8 9 7 11 22 8 26 17 17 6 7 15 7 12 9 15 7 10 3 20 6 10 32 20 11 9 22 10 '.) 9 3 6 7 14 7 12 7 16 1^ 20 7 13 1 23 20 23 14 3 20 12 18 1 5 15 10 20 1 4 10 11 9 5 10 9 15 3 14 19 20 10 20 11 4 15 10 8 20 8 20 This tal)le shows correspondence between these two kinds of measurements. RESECTION OP THE OPTIC AXD CILIARY NERVES. 731 These, Gentlemen, are the facts I liave to bring before you. I will farther crave your indulgence while I lay before you the thoughts that have occurred to me whilst working out these cases; these I will put in the form of aphorisms to save space, but with no intention to dogmatise : — The point at which the measurements of abduction and adduction ought to be taken, is situated on that part of the horopter line at which the eyes meet with the least effort of convergence and accommodation, namely, at a point twenty feet distant from the eyes, on a line drawn from the centre of, and at right angles to, the base line. The method of measurement by means of horizontally-placed prisms is the only method by which the amount of abduction and adduction can be gauged, so as to be a guide to the power of convergence employed by the individual. That the measurement of the maximum of convergence does not give a reliable indication of the amount of convergence employed by the individual. (See Table IV.) That the absence of binocular vision destroys the normal relationship between the external and internal recti mn.scles. That the normal relationship between abduction and adduction may l)e regarded as in the proportion of one to two in the untrained. That insufficiency of the external recti so rarely produces distressing symptoms, that its- measurement may be disregarded in practice. That asthenopia, from insufficiency of the internal recti, was not found in any case where the measurement of adduction amounted to a prism of 12°. That the large majority of cases of insufficient employment of the power of adduction may be cured by the judicious use of prisms, as a means of gymnastic training, tenotomy of the opposing muscle or advancement of the insufficient muscle being seldom required. In conclusion, I wish to point out that the result of the examination of these cases has assured me, that the best indication for the need of treatment in cases of muscular asthenopia is found in the measurement of the adductive power at distance. A SERIES OF CASES OF RESECTION OF THE OPTIC AND CILIARY NERVES. By H. LiNDO Ferguson, F.R.C.S.I. Lecturer on Ophthalmology in the Otago University, New Zealand. Professor Schweigger's paper on Resection of the Optic Nerve, in Vol. XIV of " Knapp's Archives of Ophthalmology," is undoubtedly the most important contribution to the literature of the subject that has appeared of late years. In it, he deals so fully with the objections which have from time to time been raised against optic neurotomy, and points out so clearly the safety against sympathetic dangers, ensured. by resection of a portion of the nerve, that 1 should be merely para- phrasing his sentences, if I were to detain you by entering into the .subject at any length. 732 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Ill September 1886, Dr. Bell Taylor published in the British Medical Journal a report of thirty-one cases in whicli lie had performed the operation, and his results, together with Schweigger's paper, induced me to adopt it. Any alternative that will secure protection to the fellow eye in cases where there is risk of sympathetic inflammation, whicli stops short of removal of the injured organ, will be equally acceptable to the patient and to the surgeon. Excision, though it often terminates the patient's troubles in the way of pain or risk to the other eye, is very frequently the beginning of a series of annoyances, in the way of purulent discharge from the con- junctiva and discomfort, with an artificial eye ; or lachrymation, and collection of dust and foreign bodies in the orbit, without one. Of late. Mules' operation of introducing an artiticial vitreous has been brought prominently forward, but it does not obviate the drawback of having to wear an artiticial eye, and merely improves the stump on which the shell rests. Wliether it secures immunity from sympathetic trouble remains to be seen ; but there is no doubt that the class of cases, where the lids are too irritable to stand an artificial eye after excision, will stand it no better because it is supported by a metal ball inside the stump. In a very large number of cases calling for operation, the eye to be dealt with is as sightly, if not more so, than the artiticial eye which replaces it ; and even when this is not the case, most patients prefer to retain their eye, unless the disfigurement is extreme. I have operated on fifteen cases since November 1886, in all of which I should otherwise have had to excise, and had once begun the operation, but been obliged to excise. This case was one of severe injury to tlie cornea and sclera from glass, which had healed imperfectly, and as there was very severe pain, I operated at once. During the operation the wound ojDened, and I was obliged to remove the globe. All of the other fifteen cases, except the last, which is only recovering from operation, and of which I cannot speak, have been most satisfactory in their results. I have seen no material return of coi-neal sensibility, and have seen as much relief of sympathetic irritation in the other eye as if I had excised. In Case X, symj^athetic iritis set in on the sixteenth day, but there had been sympathetic irritation before the operation, and excision would probably have been no greater safeguard. So far as the cosmetic result of the operation in these fourteen cases is concerned, the appearance, except in Case X, was the same as before interference, and I have no reason to suppose the last case will do any worse than the others. Of course, the operation is not adapted to every case ; but in many instances where excision is now practised, I have no doubt a fi'eely movable eye of presentable appearance might be pi'eserved if resection of the nerve were adopted, and the cosmetic effect is known beforehand, wliicli is not the case with excision. I pej-form tlie operation by dividing the tendon of the internal rectus, fl,nd freely di\iding the conjunctiva and capsule of Tenon upwards and downwards at the same time. The middle needle of three on one silk is then passed through the divided muscle from within outwards, as if for advancement of the muscle, and the suture is drawn across the bridge of the nose out of the way. The globe is then rotated outwards by means of a small sharp hook, and the nerve divided as far back as RESECTION OF TIIR OPTIC AXD CILIAHV NKKVES. 733 possible with a curved scissors. A strabismus hook is slipped round the portion of the nerve attached to the globe, and used to rotate the eye till the posterior pole appears in the wound, when the nerve is snipped oft' close to the sclerotic, and the ciliary nerves cut off short. The globe is tlien replaced, and the rectus stitched forward to the conjunctiva aboAe and Ijelow the cornea. The lids are cai'efully closed, and a compress of lint, wrung out of carljolic oil, used as a dressing. The stitclies cause no inconvenience, owing to the insensiti^•eness of the cornea, and are removed on the third or fourth day. The last opera- tion, from introducing the speculum to pinning the bandage, took twenty-one minutes ; bvit if the haemorrhage is smart, it may cause delay in getting back the eye into place, and make the operation more tedious. The following notes of the cases speak for themselves, and do not require any furtlier explanation : — Case I. C. P., aged 8. Oc. Dex. was lost some months previously from a blow from a stick at whicli he was chopping on the ground. The stick tiew and struck the eye, penetrating the cornea and wounding tlie lens. At the time of operation, he had an occluded pvipil and anterior synechia. The cornea was somewhat shrunken, and the globe was very sensitive, especially in tlie ciliary region below. Oc. Sin. was showing signs of sympathetic irritation. Tliere was sufficient intolerance of light to prevent ophthalmoscopic examination, and a great loss of accommodation with some conjunctival irritation. Half an inch of the nerve was excised in November 1886. When last seen, in September 1888, he was attending school, and the left eye was normal in every respect. The injui*ed eye had perfect movements, but hardly any corneal sensation, and would stand stroking with a piece of paper without winking. The eye was absolutely quiet, and there was nothing to show that an operation had been performed. Case II. H. F., Jet. 35, sailor, presented himself on No^ ember 10, 1888, ha^ing• had his right cornea ruptured right across, below the centre, by a blow from a marline spike eight weeks before. The iris was adherent in the cicatrix, and the pi'ojection of light was bad. Oc. Sin. V. = f , some letters, and J 1 with effort. Ophthalmoscopically, fundus normal, but very sensitive to light. He was admitted to the hospital for observation, and some days later, the intolerance of light increasing, V' of the nerve of the injured eye was resected. He left the hospital a foi'tnight later with perfect motions of the globe, and very slight corneal sensation. The intolerance of light in the other eye had quite disappeared. Case III. T. B., aged 17, on November 24, 1886, gave the following history: — Two months before, in opening a sodawater bottle, it burst, and one of the fragments struck his right eye. There had been considerable pain, which had gradually subsided, but vision had not returned. There was a long cut from the equator inside, running forwards and rather downwards to within two millimetres of the corneal limbus. 734 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. This was lirmly healed by a somewhat depressed cicatrix. The cornea was normal, but the iris was pressed forwai'ds against it in its inner and lower portions. The lens showed commencing opacity in its outer lower quadrant. The retina was detached on its inner side, and there was a considerable cyclitic membrane along tlie cut, involving the retina. The nerve was veiy hazy, and the vessels of the attached portions of the retina were very hazy. In the macular region, was an exudation similar to that in albuminuric retinitis. V = Fingers at 0*3 millimetres, T-3; Oc. Sin. V = |^ and J 1. After some corres- pondence with his parents, between ^" and ^" of tlie nerve was excised on December 6. The stitches were removed on the 9th, when the eye was quiet, movement good, and cornea insensitive. On the 10th, he had an attack of acute rheumatism, and a temperature of 104°, but by the 21st he was able to I'eturn home. The eye was then quiet; the pupil was dilated and lixed, and the cyclitic membrane visible behind the lens ; the cornea was insensitive to slight irritations, such as touching with paper, but he was conscious of firmer pressure. A satisfactory report was received from the patient's father two months later, since when he has not been heard from. Case IV. Mr. G., aged 48, applied December 21, 1886, saying that he had been struck in the left eye twelve weeks before by a piece of iron, which flew from his hammer. Oc. Dex. V = -^■^, fundus normal ; V Oc. Sin. = doubtful perception of light ; T — 3. There was a linear scar from two to three millimetres long in the corneo-scleral junction above. Tlie iris was jiressed forwards almost to the cornea by the lens, which showed streaky haze in its centre ; the retina was almost entirely detached. He was admitted to the hospital, and ^" of the nerve resected. He made a good i-ecovexy, and left with an insensitive fi-eely moving globe. The right eye had improved to about V = ■^■^, and he did not care to have his manifest H corrected, to get better sight than this. Case V. J. W., aged about GO, was operated on in tlie Dunedin Hospital, in 1886, for a large orbital sarcoma which displaced the eye down and outwards, so that it lay outside the orbit below the outer canthus, completely hidden by the lower lid. He stipulated that the eye should on no account be removed, so, though the tumour was adherent to the upper inner posterior quadrant of the globe, the sclera was carefully scraped and the eye retained. In January 1887, lie presented himself, complaining of great pain in the eye, which was of stony hardness. The lens was opaque wlien he first came under observation, and there was no perception of light. He still refused excision, so ^" of the nerve was excised without difficulty, and some months later he remained free from pain and with a presentable eye. He was lost sight of about the middle of the year. Case VI. Mr. Wm. G., aged 45, presented himself November 8, 1886, stating that he had been struck in Oc. Dex. by a " spark," when quartz reefing RESECTION OF THE OPTIC AND CILIARY NERVES. 735 nine months before. V subsequently was nearly normal till three or four months befoi'e the visit, when it began to fail, and the iris began to change from a blue grey colour to a light brown. When seen, Oc. Sin. was normal, V = §, iris light blue. Oc. Dex, V = Fingers at 0"5 millimetres. The cornea showed a cicatrix two milli- metres long, running inwai'ds and downwards from the outer limbus. The iris was light brown in colour, showing slight indications of the old blue colour near its base, inside and above. It showed a laceration beliind tlie corneal cicatrix, corresponding with it. The anterior capsule was completely covered with a tine powdery cloud of pigment spots, denser in some spots than others. Tlie lens behind showed a dirtuse haze. He projected light well, except on tlie temporal part of the retina, where the projection was slow and uncertain. Being disinclined for operation, he was told to remain under observation. He returned on April 9, 1887, suffering from headaches. The lens was now completely opaque, and the projection of light very bad. V Oc. Sin. f . As there was no doubt as to the presence of a foreign body in the eye, he consented to operation, and on April 13th, ^" of the nerve was resected. He was very drowsy on the two following days, but on the third day, when the stitches were removed, he was much brighter. On the fourth day, there was doubtful corneal sensatio)i, and motion was good in all directions except outwards. On the 18th, outward rotation was better, and he left for home. On the 27th, he reported that he had been exposed to cold, and had suffered severe pain in the eye, which had ceased two days before his return. Rotation outward was slightly defective, but was good in other directions. The cornea was very slightly sensitive, and the eye was quite quiet. Oc. Sin. normal. He has not retui'ned since, but his employer has at intervals I'eported to me that he is well and free from discomfort. Case VII. H. L., a miner, was operated on in April 1887, for a rupture of the cornea from side to side. He was discharged from the hospital a fortnight latei*, with a freely movable stump and doubtful corneal sensation. Case VIII. C. B., aged 33, miner, had his right eye injured by a blasting accident in February 1887. On April 20, the stump was very tender. The cornea was much cut, on'e cut extending into the ciliary region above. The iris was incarcerated in the corneal wounds on its temporal side. Lens opaque. T - 2 ; V = P. light ; Oc. Sin. V = § letters. Some intolerance of light. Tlie right nerve was resected on April 21st, and on May 13th he returned to work. V Oc. Sin. =|^ and J 1 ; intolerance of light gone. The injured stump was not tender, looked fairly quiet, and had an insensitive cornea. He reported two months later, and his condition was then satisfactory. Case IX. Master T. C, aged 7. First seen on May 12th, 1887. A soda ■water bottle had exploded three weeks before, and a fragment had 736 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. entei^ed his left eye. His mother was witli him at the time, and drew out a piece of glass which projected from between the closed lids. There was a depressed scar from the ciliaiy region outside, extending down and back to the equator. Over the ciliary portion of the scar, was a granulation. The retina was extensively detached. T - 2. No perception of light. The stump was excessively tender to the touch. Oc. Dex. normal. The nerve was resected on the same day ; the stitches were removed four days later, and on the 20th he returned home with a painless insensitive stump. Two months later, the eye was reported as being still bloodsliot, but free from pain or sensibility, and his medical attendant (who is a careful observer, and occasionally writes to me) has not since reported anything wrong. Case X. Thos. S., aged 30, presented himself on January 6th, having had his right eye injured the pi'eviovis day. He was sewing sacks, when the twine broke as he was pulling it, and the packing needle entered his right cornea. V = P. light ; lens opaque ; T. low n. The wound was across the pupillary area, and the iris was incarcerated in the outer part. He was admitted to the hospital, and the anterior synechia was cut, and a considerable portion of the opaque and swollen lens was extracted. The case, however, ran on to plastic cyclitis, and I advised resection of the nerve. This he refused for some weeks, but consented in the latter part of Febi'uary, as he felt his left eye failing, though there were no recognisable changes in it. The operation was attended by severe hsemorrhage behind the globe, which forced it out between the lids. After very great difficulty it was reduced, and the lids closed. On the following day the eye was again protruding, and could not be thoroughly reduced, but steady pressure was kept up over the globe, which in about a fortnight was in good position, though outward rotation was very defective. The cornea was infiltrated with pus on the third day, but cleared up after threatening to necrose for over a week. On the 16tli day, he had a mild attack of sympathetic iritis in the left eye, which, however, readily yielded to treatment. On May 23rd, he had V 3-% without lens, f letters + 1 D Oc. Sin., and the right eye was a presentable stump, with good motion, except outwards ; but outward rotation seemed to be improviiig. The cornea of the stump was absolvitely insensitive. Case XL C. B., aged 8, was operated on in the hospital on April 18, for a perforating wound of the ciliary body Oc. Dex. Operation and recovery were normal, and he was discharged in a fortnight Avith a painless, insensitive, freely movable stump. Oc. Sin. normal. Case XII. Mrs. S., aged about 45, was operated on in the hospital in June last. She had absolute glaucoma in botli eyes, for Avhich iridectomies had been done .some years previously. She was suffering intense glaucoma- tous pain in the head from the right eye. During the operation, the ciliary nerves were found to be enormously enlarged, aixd fully f ' of RESECTION OF THE OPTIC AND CILIARY NERVES. 737 them was removed. She later complained much of pains, which she could not locate, in tlie back and stomach and globus hystericus. These symptoms were referable to the menopause, but the glaucomatous pain ceased absolutely from the time of operation. When discharged, except by some conjunctival redness, the eye operated on could not be dis- tinguished from the otliei". Case XIII. C. B., aged 52, lost Oc. Sin. thirteen years ago by an accident. He had severe intlanunation, and was many weeks in hospital. He has always since had tenderness in the eye, and has been liable to severe pain from such trivial causes as touching it while washing his face. When seen on August 28 last, he said the eye had been very painful for two months, and for four nights he had not slept. V. no P.L. T — ? great ciliary tenderness. There was a scar ^" long running through the outer limbus of the cornea into the ciliary region, in which the iris was incarcerated. The pupil was drawn to the edge of the coi'nea, and the lens was opaque. Great ciliary congestion and duski- ness. Oc. Dex. V = Y^2 j nerve distinctly hypersemic. The nerve was resected next day, and the pain ceased at once. He was discharged a fortnight later with a freely movable, quiet, insensitive stump. The riglit eye was quiet, and V had gone up to letters of f . His delight at being able to wash his face, without hurting his eye, was quite comic. Case XIV. Master W. A., aged 15, was brought to me on August 27 last, having had his right eye injured by a steel fork ten days previously. There were two perforating wounds of the cornea, at the level of the upper pupillary margin, to which were fixed two fine threads of iris. The pupil was contracted and much bound down, and there was great ciliary congestion. Lens opaque. T.n.; projects light badly. Every efibrt was made to dilate the pupil without success, and the boy's father consented to resection, when the left eye began to lose its accommoda- tion. The wounded eye then had T— 1, ciliary tenderness, a completely occluded pupil, and iris bulging forward. Oc. Sin. V = f and J 1, slowly and with difficulty. The nerve was resected on September 24, and there was some proptosis, but the lids covered the lids after some trouble. On the 29th, the stitches were removed ; some conjunctival sensation, but none in cornea. October 1. — The bandage was removed. October 17. — When last seen, eye quiet and movements perfect; no corneal sensibility. Oc. Sin. is strong, and bears the light well, V = § and J 1 easily. Case XV. R. S., aged 58, had his right eye injured by gorse five months before he applied at the Dunedin Hospital, on November 16, 1888. The globe was then flattening under the recti, and was in a condition of chronic cyclitis, and excessively tender. The lens was opaque, and the iris adherent all round the pupillary margin, and vision was absolutely destroyed. The other eye was " feeling weak," ])ut had no inflammatoiy condition. He was suffiering great pain over the right side of the head, 2b 738 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. radiating from the injured eye. Three days ago (November 19) three- quarters of an inch of the optic nerve was excised, and the proptosis, after the operation was complete, was nearly half an inch before the other eye, leaving fully one inch between the end of the nerve in the orbit and the globe. There was pain on the following day, which ceased on re-adjusting the bandage, and has not returned. To-day he is quite easy, and the proptosis is diminishing. SANDY BLIGHT AND GRANULAR OPHTHALMIA. By T. Aubrey Bowen, L.K. et Q.C.RL, M.R.C.S. Eng. In this paper 1 have used the term " Sandy Blight " (muco-purulent ophthalmia), as it is the popular term for perhaps the best known and the most frequently occurring disease in these colonies. At certain seasons of the year, notably in the middle and late summer months, it commences in a spoi'adic form, occasionally becoming epidemic in limited areas, and attacking a whole district, so that the State schools have from time to time to be closed for some weeks. Both in the endemic and epidemic forms, the sequela? of this disease have been by far the most frequent cause of blindness in the colonies; not on account of the serious nature of the disease at its commencement, but owing to its being allowed to continue in a chronic form, inducing trachoma, pannus, ulcers of the cornea, and all the disasters resulting thei-ef rom. Certain varieties of trachoma are so intimately associated with this disease, that it will be difficult to make any observations on the subject of granular ophthalmia, as it is oftenest seen in the colonies, without also glancing at this so-called blight. The subject of trachoma, or granular ophthalmia, is a most difficult one to deal with, both as regards its causation, its essential nature, and its treatment. The nomenclature is both imperfect and deceptive, and the words " granular ophthalmia " and " trachoma " are used by some as synonymous, and by others as expressing different diseased conditions. Others again give names in accordance with the particular theories they hold as to their distinctive characteristics, such as follicular and papillary granulations, and hypertrophy of the papillfe — these three forms being held as essentially different diseases. Others, as Von Arlt, regards the blenorrhcea of gonorrhoea and that of ophthalmia neonatorum as the same disease in the acute form as follicular and papillary granulations in the chronic form; and that these diseases only diii'er from one another partly by the rapidity of their course, and partly by the changes that take place in the conjunctiva. M. Wecker considers wliat he calls true granulations as new deposits analogous to tubercle. There is great diversity of opinion as to whether these granular bodies are new formations, or alterations of the adenoid tissues already existing. At present, I do not tind any satisfactory evidence as to these granules being the product of a specific micrococcus, and having a distinct origin or running a different course from the other SANDY BLIGHT AND GKANULAR OPHTHALMIA. 739 altered states of the conjunctiva in tliis ati'ection. T cannot agree that we are in a position to draw deductions as regards nomenclature or treatment from the present uncertain state in which the question stands. Sattler, ^Michel, and one or two others believe that tliey luive found a specitic micrococcus in the granular bodies, and that they have reproduced a similar disease with the cultivated germs; but their conclusions have not been sufficiently corroborated Ijy other investi- gators. I am perfectly prepared to believe that this disease, in common with a very large number of others, is caused by micro oi'ganisms ; but, granting that this may be true, the question still remains open — whether these same organisms are not also present in other forms of the disease. The more we consider the study of micro-organisms in connection with disease as of paramount importance, the more cautious we should be in admitting all the numerous so-called discoveries as proven, until they have l)een subjected to the test of time, and the unanimous concurrence of a large number of experienced workers in the same held. I do not tind that the usual descriptions of trachoma at all accurately represent the forms of the disease as it exists in the colonies ; nor are the various gradations nearly so clearly marked as usually described. On this account, I have thought it might be of interest to give my impressions of the disease, after having watched its progress in Hospital and private practice for twenty-five years; during which time I have had a very large number of cases pass through my hands, and have been able to contrast it with the disease as I have seen it in Egypt, Ireland, and England (although in England it is rare, in comparison to its frequency in the other counti'ies). In these colonies, it is perhaps more prevalent than in any paii of the Globe inhabited l)y Europeans. I am inclined to the belief, that the various forms of trachoma are modifications of the same disease, but differing in degree; and that one form may reproduce another foi-m, modified by the manner of transmission, and by the surrounding circumstances of the case. Some years ago I attended, on behalf of tlie Government, a very serious attack of purulent ophthalmia in the State Schools for children, in which many hundi'eds were attacked, and a large number lost one or both eyes. I have already described this epidemic, and only mention it now to point out that the forms of trachoma left after the subsidence of the disease were markedly different. In some, there were the well- marked sago grain bodies ; in others, these were never visible at all (and I watched the progress of all the cases from day to day), but only the enlarged and hypertrophied villi and conjunctiva. Through the kindness of my confrere, Dr. J. P. Ryan, and in conjunction with him, we examined over four hundred of the children at Abbotsford. Amongst a large number of them, trachoma was present in a greater or lesser degree. In some, the sago grain bodies were visible, but in by far the greater number they were not present; and in the cases in which they were seen (a strong lens was used), the enlarged villi gi'eatly predominated. Blight has several times visited this school, and, a large number of the children have been attacked, but not in a severe form, or as an epidemic. I cannot help thinking that it would be much better, whilst there is any serious difference as to the causation and essential nature of this disease, not to give a name or names in 2b 2 740 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. accordance with the particular theory of its nature or development, but for a time at least to describe the conditions simply as we see them, and on these grounds I should like this disease of granular ophthalmia not to be subdivided, but all forms to be classed under the sole name of ti'achoma, or trachomatous eyelids — signifying simply rough eyelids. I will now give a brief outline of the disease popularly known as sandy blight in these colonies. It is simply a muco-purulent con- junctivitis, and commences with a slight redness and itching of the conjunctiva of the lower eyelid. This soon extends to the ujjper lid and the globe; and on the second day, the eyelid swells moi'e or less, according to the severity of the case. There is usually a considerable amount of pain about the third or fourth day. On everting the upper lid, it is found somewhat roughened by the enlarged and swollen papilla:;, a muco-purulent discharge exudes from the eye, but unless in a very severe case, it is more of a mucous than a purulent character ; frequently however, in constitutions debilitated by drink or disease, and with vmhealthy surroundings, the disease takes on a decidedly purulent character, and the resulting trachoma (supposing the case is not properly treated) and pannus are of a far more serious character than in an ordinary case. All the prominent symptoms fade away in aljout a fortnight with ordinaiy cleanliness, and not much discomfort remains, and in this freedom from any serious annoyance lies the danger. In a large number of these untreated cases, the disease continues in a chronic form ; a slight mucoid discharge comes from the eyes during the night, or in a glare or strong wind ; and if the lids ai'e examined, the enlarge- ment and thickening of the papillaj can be seen to be slowly progressing, exudation of lymph is taking place into the tissues, thickening the lids, and in course of time, if nothing is done, pannus, ulceration of cornea, and all the other sequela? take place ; whilst in this chronic condition, as in gleet and other diseases of mucous membranes, exposure to cold, drinking, and other like causes, renew it with much of its original vigour. Blight is much more common in the country than in the towns, and amongst children than grown up people. It is rare except in the summer months, and is in a worse form at a late than at an early period of the summer. In looking for the causes of this disease, we must separate those which give it a chai^acter endemic to a particular country or district, and those which immediately concern its production in an epidemic form in a limited area. There can be no doubt that the usual causes inducing inflammation of mucous membranes are operative, as cold air draughts, dust, and especially Aiolent alternations of heat and cold : and in tlie case of the eyes, bright light will occasion the affection. A bright sun (especially when x'eflected from a briglit-coloured sandy surface) is without doubt an irritant to the eyes, and predisposes them to disease. The dust also, especially when it exists in an almost impalpable powder, acts very injuriously. We know that damp is a great medium for carrying the poison of many infectious diseases ; and I consider one of the chief causes of the propagation of this affection by contagion is an atmosphere loaded with moisture, whether produced by evaporation after a liot day, or from the moisture exhaling from the bodies of a large number of people crowded together in badly ventilated sleeping apartments. Both these causes may act at once, and usually SANDY BLIGHT AND GRANULAR OPHTHALMIA. 741 exert their influence on eyes predisposed to take disease from previous exposure to tlie sun, dust, Ac, and in constitutions debilitated by fatigue, drinking, improper food, or insufficient exercise. One of the principal causes of the disease in its simple form here is exposure of the eyes to the sudden changes of temperature in the early morning, Tliis change is very great in tlie summer in our climate ; and in tlie country districts, people, especially the young, often sleep during t!ie hot weather in exposed places, where they are subjected to its full force. In towns, they are usually in rooms more protected from atmospheric influences. Formerly, in the early days of gold-mining, when teams with large parties of miners, Arc, went to the diggings, sleeping in tents en route, a large number of the party almost invariably had blight. It is a common practice amongst the Tent Bedouins to cover their eyes at night in order to guard against a similar change that takes place in Egypt. The great decrease in blight and its consequences, that has taken place of late years from year to year, I attribute in great measure to the improved conditions in which the farmers and miners now live. They generally have fairly comfortable cottages, instead of log huts or tents. This disease is, without doubt, both contagious and infectious, but it is certainly by no means exclusively or chiefly to be attributed to tills cause. My own opinion is, that it is highly contagious, but infectious only in a minor degree, and in a suitable nidus. * I have given an outline of this disease, as I consider it is by far the most frequent cause of trachoma in these colonies, and of the irreparable damage that may be caused by neglecting its treatment — a disease so easily cured, and if untreated, leading to such disastrous results. This neglect is now being, to some degree, remedied by the greater facilities the country people have of reaching a doctor, and by the greater knowledge the profession now possess of the treatment of the disease. For my own part I have found fomentations, with or without leeches, in the acute stages ; and alum washes, with or without weak nitrate of silver drops, in the later stages ; with absolute cleanliness throughout, amply sufficient in nearly all cases to eftect a cure, and leave no trace of enlarged papillae behind. In sjDeaking of trachomatous (or rough) eyelids, as I have before stated, the sago-like bodies or granules are comparatively rare in this country, and are intimately associated with the other forms of trachoma. I have seldom seen them alone ; and it is very rare here to see a case of trachoma, which has not been preceded by some acute or long-continued sub-acute form of conjunctivitis, and generally no history of previous weakness of the eyes can be gathered. In the large Military Eye Hospital at Cairo, I have frequently seen cases of old trachoma, with tlie conjunctiva smooth and bright, but studded witli small, hard, round seed-like bodies, embedded in the conjunctiva, and wliich can be picked out with tlie point of a knife, and wlien placed on the palm of the hand can be rolled about like marbles. These I have never seen here. * By Contaijion, I mean immediate contagion, communicated through a material and visible substance. By Infection, mediate contagion communicated through the medium of the atmosphere, and invisible substances suspended in it. 742 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Of the trachomatous patients who have passed through my hands, I have not found any great predominance of a particular nationality. It is rare amongst the Jews, which I attribute to so few of them living in the bush, and out of reach of medical attendance ; and it is certainly rather more prevalent amongst the Irish, this I attribute to an exactly contrary reason — so many of the poorer classes of this nationality being small settlei^s, and gaining a mere subsistence. Pannus, here as elsewhere, is a very common accompaniment of trachoma ; and ulcers of the cornea also are far commoner here, in my experience, than in England, as a sequela of the disease, and are the most frequent cause of blindness, as they render it difficult, and often impossible, to properly treat the trachoma. I do not think it is of much use to attempt to cure the pannus until the trachoma is sufficiently recovered to enable us to beneficially treat the two together. The cicatricial bands in the conjunctiva of the upper lid, occasionally met with in old cases, are as often, I think, caused by the free use of solid caustic — which was formerly a common method of treating trachoma — as by contraction caused by changes in the granules. I do not intend to say much as to the treatment of this disease. It is sad to contemplate the infinite number of remedies that have been tried, extolled as almost specifics, and now fallen into utter disuse, or only used once in a way as of doubtful utility, and it has a tendency to shake one's faith in the wonderful results constantly reported of new methods of treatment. Of course, this may be accounted for to some extent by the fact that in this, as in other diseases, the same remedies iict in a very diflerent manner in diftei^ent persons, and in accordance with the various phases of the disease and of the constitution. I haA-e not found shaving the tops of the villi of much use, although when they are very large and vascular, the bleeding may do good sometimes ; a better plan is scarifying. Nor have I found much benefit from the actual or thei'mo cautery. I have not used the electric cauteiy sufficiently to form an opinion. Dr. C. Bell Taylor has adopted a method (in accoi'dance with the bacteria theory), of squeezing out the granules and scarifying, and afterwards applying liquor potassiB. I very rarely indeed meet with cases in which the sago gi'ains are sufiiciently isolated or numerous, and unaccompanied with enlarged papillte, to apply this treatment with any hope of success. He also in some cases, in common with others, excises the I'etro-tarsal fold. I have made trials, in some cases ^^rolonged ones, with tannin, perchloride of mercury, and others of the numerous forms of treatment that have been from time to time advocated, such as the aqupe chlorinatte so strongly recommended by Graefe, Pagenstacher's yellow oxide of mercury ointment, Worlomont's — cantharides, sulphate of copper, and glycerine ; Bowman's spirits of turpentine and olive oil, &c. itc. ; and although tliey ai'e most of them undoubtedly useful in certain cases (I have found the perchloride particularly so), I have as a general rule come back to the thi'ee old remedies of the mitigated nitrate of silver stick, applied lightly to the lids, and afterwards neutralised ; followed by the sulpliate of cop])eT', divine stone, or a brush OAer with a ten or twenty grain solution of nitrate of silver, neutralised after a short time, as the most reliable i-emedies in bad cases of trachoma. Local depletion and counter-irritation are of course used from time to time. GRANULAR CONJUNCTIVITIS. 74^ Jequirity is undoubtedly a valuable remedy in extensive pannus ; the effects produced are somewhat alarming in appearance ; but unfortu- nately, the cases in wliicli it is safe to use this remedy are far from numerous, as they are often accompanied with corneal ulceration, either existing, or with the scars from former ulcers ; in such cases it would not be prudent to employ jequirity ; the effect, however, as with inocula- tion of pus, seems to be rendered safer when preceded by the operation of peritomy. Peritomy T have very frequently performed, and have seen the results after months, and in some cases years. The effects are veiy slow in arriving, and T do not consider the results as a rule satisfactory. The pannus is often greatly cleared away, but a general corneal haziness is often left, in many cases permanently. I do not know any remedy that supersedes prolonged treatment, patience, and extreme care, and watching, the general health being very carefully attended to, and the frequent febrile attacks to which these patients are liable combatted. With these means, I think almost all cases are curable if the pannus is not too thick, and no ulceration exists. We have here a veiy large number of cases of young people, with only a moderate amount of trachoma and pannus of not a very pronounced character. The health is generally much impaired, fi'om the constant suffering and misery. In these cases, for some years, I have been in the habit of using the following method of treatment : — T tell them to place as much as two pin heads of quinine, in the linest possible powder, between the lid and the eyeball every morning ; and at night, a drop of solution of sulphate of atropine, two grains to the ounce. I also give them a tonic, usually syrup of the iodide of iron, and tell them to bathe the eyelids for a minute or two, three or four times daily with cold water. After a short time, I have found the pannus to disappear in a satisfactory manner, and the conjunctiva to become of a pearly whiteness ; the ti-achomatous condition of the lids at the same time slowly but satisfactorily lessens. I am so satisfied with this method of treatment, that I am anxious my confreres should give it a trial. It of course does not succeed in all cases, and does not seem suitable in grown up people. GRANULAR CONJUNCTIVITIS. By R. B. Duncan, F.R.C.S. Ed. (l)y Exam.), Kyueton. Hon. SurfTeou, Kyneton Hospital. Late Clinical Assistant, Glasgow Ophthalmic Institution. Granular conjunctivitis is a disease that has always occupied a pro- minent position in ophthalmology. It is not so much that it is a disease which often proves fatal to useful vision, lint that it is one almost invariably of long duration, most difficult to cure, and when aiiparently cured, liable to frequent relapses. This disease may be said to have made its first appearance in Europe in 1798, when it was imported by the French army on its return from 744 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Egypt, lience the name " Egyptian ophthalmia," by which it is sometimes designated. There is reason, however, to believe that in Italy at least, it was known long anterior to this date. At the periods of which I speak, its propagation was easy, and its results wide-spread and disastrous. It is only within recent years, however, that its causation and mode of propagation, the various social conditions with which it was associated, its insidious beginnings and rapidity of spreading in reformatories, barracks, and prisons, or wherever large collections of people were congregated under bad hygienic conditions, have been investigated and studied with a care and discrimination which leaves little to be desii'ed. The chief causes, then, of this disease, in its epidemic form at least, may be traced to the " overcrowding of human beings, together with filth, impure air, want of proper food ; and, in fact, deficient sanitary arrangements in general are doubtless the most ])rolific sources of this disease, and are capable of not only causing conjunctivitis in men, but also in the lower animals."* What I wish to speak of to-day, more particularly however, is the granular conjunctivitis in its isolated forms, as we generally meet with it in ordinary practice, in contra-distinction to its existence in communities to which I have just alluded. And first, as to its name. There is no term in ophthalmology which is more confusing, or which more absolutely misrepresents a disease than this. As if the designation "granular conjunctivitis" was not enough to make "confusion worse confounded," other terms have crept into our nosology; hence the names trachoma, Egyptian ophthalmia, military ophthalmia, follicular, papillaiy, and even vesicular conjunctivitis. I am not prepared to ofler any sug- gestion in the way of curtailment of this formidable nomenclature, but it is to be hoped that systematic writers on the subject will, in the near future, find a means of designating it more in keeping with its pathology. The appearance of an eye affected with granular conjunctivitis is not always characteristic, and will depend to a great extent on the stage of development reached by the granules. At times, a magnifying glass will be required to make them out. In the majority of cases, however, they are observable as small semi-transparent bodies, occupying chiefly the upper and lower tarso-orbital folds; but, by preference, the latter. They often attain the size of boiled sago grains, to which they have been com])ared. What, then, is their structure, and what are the pathological conditions producing them 1 This question is not easily answered, since opinions regarding the histology and pathology of trachomatous granules are at present in a transitional state. They consist, according to Pollock, " of collections of lymphatic corpuscles, enclosed in the meshes of a delicate reticulum, the whole being invested by a capsule, formed by a condensa- tion of the normal tissue." More recent investigations, however, have shown that their anatomico-pathological structure is not quite so simple. Is a granule in fact a perfectly new formation, or a mere hypertrophy of a jjre-existing structure 1 It is a new formation undoubtedly, and not only so, but the seat of a specific micro-organism or tracliomacoccus. Considering the nature of the disease, and its intensely contagious charactfT when combined with a discharge, something of this kind was * " A Manual of Diseases of the Eye " (Macnamara). GRANULAR CONJUNCTIVITIS. 745 long suspected. Its important bearing on the subject of treatment will be discussed further on. By adopting this view of the matter, some features of the disease, which liave always been more or less inexplicable, are easily explained. It is quite evident that the question is chiefly a bacteriological one, and from that side only will it advance. A dis- tinguished writer (Arlt, " Pathology of the Eye ") on the subject tells us, that the chief characteristics of a granule are "tubei"cle-like aggregations of round cells;" while another informs us that they are purely composed of lymphoid cells. Both opinions are to a certain extent correct, but they do not advance our knowledge of this important matter in any way. Any elucidation of this question then, from a new standpoint, is to be welcomed. It may be stated that the human conjunctiva at least contains no lymphatic follicles. " Small collections of lymphatic cells may be found in it, arranged in clusters." A trachomatous granule being a new formation, what are the conditions of its development? Given a healthy human conjunctiva, to which some of the discharge from one affected eye has gained admittance, and what is the course of events 1 Modern bacteriological research has placed it beyond a doubt, that the disease depends on a specific trachomacoccus, which finds its s})ecial seat of development in the sub-e})ithelial connective tissue. How does it get there, and in what manner is it possible that it can penetrate an apparently intact and healthy membrane 1 Various conjectures have been hazarded to account for this, but with as yet no satisfactory result. •'Once introduced, however, the changes begin, and like many diseases due to a micro-organism, have a distinct period of incubation ; and it is not till the end of the second week that the external manifestations of the disease are visible. If a section of a trachomatous granule be examined, say about the tenth day from the entrance under the con- junctiva of the specific germ, it will be found to consist chiefly of white blood corpuscles and lymphatic cells, having no particular arrangement, and no definite investing membrane. As it attains maturity, however, the collection of cells is permeated by a fine reticulum, and acquires an investing membrane. The early growth and development have not yet been worked out with that accuracy of detail, which the importance of the subject demands. As the result, however, of recent investigations, we are justified in assuming — (1) That granular conjunctivitis is a disease due to the development of a specific germ in the conjunctiva. (2) The specific germs penetrate into the sub-e])ithelial connective tissue, and produce there an irritation capable of determining the migration of white blood coi'jmscles from the neighbouring blood-vessels. (3) The parasitic germs collect in the pi'otoplasm of these cells, and the cells themselves by a series of modifications produce the finely interlaced fibres which constitute the delicate connective tissue stroma of the granulations. (4) A granulation, in all its surroundings, is formed by new elements proper to it alone.'"* The papillary variety of conjunctivitis is essentially different to that just alluded to. Here we have a true hypertrophy of existing structures, * Staderiui, " Annali di Ottalmologica," Anno xvi., Fasc. 5 e. 6. 740 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. modified according to whether they are merely an accompaniment of the follicuh\r variety, or the result of some preceding purulent or gonorrhffial inflammation. In the first instance, they are usually hard, and somewhat whitish ; in the latter, soft and succulent. In structure, they do not differ from papilhi3 elsewhere. When they exist in any considerable quantity in conjunction with the follicular variety, the term "mixed gi'anular conjunctivitis" will sufliciently indicate the connexion. Though scarcely alluded to by some authors, there can be no doubt of their great importance, and the damage that they are capable of inflicting. While always due to some present irritation or previous inflammation, they are often, on that account, most rebellious to treatment. There is a form of the disease we are discussing, which has been termed " malignant," and which is fortunately rarely seen. In the so-called malignant form, we have a combination of papillary and follicular con- junctivitis, on a most extensive scale. The whole of the conjunctival membrane, even including the cornea, is the seat of granulations; and the latter, in addition, is generally in a state of hopeless pannus. The chief feature of this disease is, however, seen in the lids. These are thickened to an extraordinary extent, and the tarso-orbital folds almost filled with fleshy-looking masses. What are the causes of this formidable affection, and do we find an ordinary granular conjunctivitis progress to this almost hopeless condition 1 In my experience, this malignant variety shows some exceptional aspects from the first, in marked contra-distinction to the ordinary variety. This is generally . shown by the i-apid sjjread of the granules, or their almost simultaneous appearance on conjunctiva and cornea, the lids keeping pace in their thickening and induration. The real cause, if cause there be, for what is possibly after all only an aggravated degree of a less serious trouble, is qi;ite obscure. Granular conjunctivitis falls into two well-marked divisions, regarding which it is necessary to have the clearest possible understanding. In the one class, we have granulations in various states of development, without any ])erceptible discharge, and with little external manifestations to indicate their presence. In the other class, we have granulations attended by a discharge. This discharge, as we all know, is distinctly contagious, and can give rise to granular conjunctivitis in a healthy eye Eyes belonging to the first category are exceedingly prone to be affected by the second; hence the imperative necessity in public institutions, such as reformatories, of thorough inspection and careful isolation on the slightest appearance of the disease. Finally, the non-discharging kind are liable to inflammatory action at all times. These distinctions are valuable, no less in private than public practice. I had a patient lately who suffered from the disease, and had a mild discharge, from whom enquiry elicited the fact, that other members of the same family were suffering from what she termed "weak eyes." Further investigation showed the supposed weak eyes to be distinctly granular. They were not considered sufficiently bad by the parents, however, to demand treatment. That this must prevail to a considerable extent is evident from the fact that, in a large percentage of our cases, the patients do not come under observation iintil the disease is well advanced. The relation of catarrhal states to the question we are considering is of high interest and importance, and in a special degree to treatment. The majority of GRANULAR CONJUNCTIVITIS. 747 text-books tells us that, where no discharge exists, sulphate of copper is indicated ; and when present, nitrate of silver solution. Such state- ments, to my mind, are calculated to do considerable harm ; and their adoption, of course, more so. Experience does not teach us that such advice is either sound, or based on correct principles. There is one feature of this disease which is always perplexing, and always a source of discouragement. I allude to the frequency of relapses. What is the cause of a relapse 1 It is not ditficult in many diseases to answer this question. But in granular lids, the individual granules of which are visible and tangible for a time, and evidently completely disappear-— what is the reason of their re-appearance? It is not re-infection ; for although recently cured granular conjunctivitis would leave a surface unquestionably more susceptible than one previously unaftected, still we have in many instances abundant evidence to show that a genuine relapse has to do with influences seated in the eye itself. Bacteriology is, I think, making it every day more clear, that a relapse is due to a specific trachomacoccus, already alluded to. For undoubtedly, in many cases, when all active manifestations of disease at least will have passed away, there will still remain some of these micro-organisms in an undeveloped state, embedded in the tissue. Their development may have been retarded during the period of treat- ment, l)ut when this has been abandoned, they have started into fresh activity. Hence the continued watchfulness necessary after an apparent cure. The division of this disease into acute and chronic stages is not a happy one. It is much better to i-egard it as essentially chronic, with acute exacerbations. The real raison d'etre of this paper, however, has reference chiefly to treatment, and the surgical management of one of its principal complications — pannus. The limits of this short paper preclude me from dealing with other complications, which are scarcely less important. There are few diseases where hygienic conditions should form more prominent a feature, than in granular conjunctivitis. " It begins in filth, is nurtured in filth, and is propagated chiefly by the same means."* A remarkable instance of this is related by Macnamara. Writing on the same subject, he says : — " An instance of the same kind will be found in certain schools in Calcutta. The children in one of these schools were of different nationalities — natives, half-castes, and Europeans — but the buildings were situated in a most filthy part of the city, and were surrounded by open drains and every conceivable abomi- nation, and granular conjunctivitis was never absent from among the boys ; whereas in other schools of a similar nature, but situated in a healthy locality, not a single instance of the disease was to be met with." It is necessary to know the domestic life, if I may so term it, of every individual patient ; and it may be affirmed that in few instances something will not he found that requires correction and advice. It is an undoubted fact, which experience almost daily confirms, that sanitary defects often defeat our best directed efforts. Whenever they can be attained, perfect hygienic conditions, suitable food, tonics, and fresh air — or, in many cases, a complete change — are always desirable, and often absolutely necessary. I was much impressed with this some years ago. * Macnamara op. cit. '748 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. A brother and a sister came under my care with granular lids, which had been iinder careful and skilful treatment for a long period, without any tangible benefit. I treated them for a considerable time with a like result ; and at last, in despair at what to do, I prevailed upon them, at great personal inconvenience to themselves, to reside in a different part of the country, and where scarcely any but constitutional treatment was adopted. On examining them some time afterwards, the disease had almost entirely disappeared. Having seen then, that the patient's surroundings are as perfect as circumstances will permit, the next consideration is the treatment of the affected eyes. Before adopting this, it is well to ask ourselves. What do we aim at, and have we any guide to treatment 1 The routine method of treatment sometimes adopted in tliis disease would almost incline one to believe that ophthalmic therapeutics had not yet escaped from empiricism. Our aim, briefly stated, is to procure absorption of the foreign products, and the restoration of the conjunctiva to a state of health. We aim at this in various ways, which are better noticed in detail. The term " papillary" may be regarded as representative of a state requiring a particular treatment. When occurring as a sequence of a previous disease, its treatment calls for nothing special; when occurring in conjunction with follicular conjunctivitis, so as to constitute the mixed variety, its treatment will come under the remarks I am about to make. I wish to allude for a moment to a class of cases, viz., those distinctly and typically acute. In these cases an amount of inflammation may have been set up, which will be sufficient to cure the granular state without our aid. Here, non-interference may be highly desirable. I alluded before to the two divisions into which granulations naturally fell — the non-dischai-ging and the discharging. First, in regard to the former, we have here granulations in a quiescent state, causing only, perhaps, slight conjunctival hypersemia and discomfort in the eye, and nothing more. There are two methods of treatment available here — To set up a sufficient amount of inflammation in the eye, which will cause absorption of the granules; or to treat them by scarification, massage, and astringents. The latter method I will deal with, in conclusion, as being the plan I prefer, and nearly always practise. Sulphate of copper, either alone, or in combination with other substances, has long been a favourite in the present affection, witii the object of setting up an amount of inflammatory action necessary to cause the disappearance of the granules. That it sometimes succeeds, is undeniable; but no one wlio has watched the time it takes to effect a cure, and its often unsatis- iactory results, would be ])repared to say that it is a remedy of much value. The reason of this is not far to seek. A remedy that we know •will be perfectly safe, so far as the integrity of the other structures of the eye is concerned, is not of sufficient intensity, in too many instances, to accomplish the object aimed at. In a typically mixed case, the remedy would have a positive disadvantage. We might, it is true, benefit the follicular granules, but not the enlarged pa{)illa3. To effect any improvement in them, our remedy must be purely astringent, and of a strength graduated to the needs; not an irritant, as the remedy we ■are dealing witli undoubtedly is, in the sense we are using it. Going back to the (piestion of the intensity of a remedy, and the desirability of its safety, it is not long since jequirity gave high promise of, in GRANULAR CONJUNCTIVITIS. 749 some measuro, ;iccomi)lisliing this desirable end; but it has not realised the expectations formed regarding it. While, at times, undoubtedly useful, it is exceedingly uncertain in its action, and doubtful in its results. The treatment of granular lids, with acute inflammatory symptoms and a free discharge, is a proljlem of gre;it complexity. Allusion has already been made to granular states without a discharge. Two factors are chiefly or solely engaged in bringing a discharge about, putting aside the question of dii-ect infection, either a certain stage being reached by the development of the granules, or some disturbance to the general health. The resulting ophthalmia is one of the methods by which a cure takes ]>lace, but except in the so-called acute form it is hardly ever successful. Nay more, it is genei-ally entirely abortive, and of little practical value. On the decline of the inflammatory attack, matters are often found worse than before it. The treatment of the discharging stage is essentially the treatment of the ophthalmia. Various remedies are in \ise for this purpose ; among which, a solution of nitrate of silver, in different strengths, occupies a prominent ])lace, so that it may stand for the whole astringent group. While clearly recognising its value in attaining a certain amount of good, it must be remembered that the objects it accomplishes are only temporary in many instances. The cure of tlie ophthalmia does not necessarily mean the cure of the disease. If it is true, however, as German and Italian investigators are endeavouring to jirove, that the disease is parasitic, the method of treatment will no doubt be soon placed on a sounder basis. And this is what is being attempted. At the conclusion of an elaborate paper, where the subject of granular conjunctivitis is studied from a purely bacteriological point of view, and the opinion expressed that the disease is due to a specific trachomacoccus, Staderini at once applies the knowledge gained to the test of clinical ex])erience. As might have been expected, the drug selected is corrosive sublimate. If this applica- tion should turn out a success, as the author declares it has, it will prove what often turns out to be the case, that empiricism has established the value of a remedy long before it was scientifically proved ; for as far back as 1825, we find Buzzi* writing that he had used corrosive sublimate for the last twenty years. His formula was — Hydrai-g. bichlor. gr. j, chloride of ammon. gr. ij, water 8 oz. This he declares to have used with the happiest results in ophthalmia and the disease under consideration. In Glasgow, Scotland, which I visited a few years since, and which was the home and field of labour of that distinguished ophthalmologist, McKenzie, I was given a prescription of his, which the donor assured me was " good for anything " in the shape of inflammation of the eye. This, strange to say, contained the same ingredients as the above, with the addition of belladonna. To enter at length into the results attained by Staderini would scarcely come within the scope of this paper. They are encouraging so far, l)ut necessarily crude and incomplete, as first investigations generally are. He recommends, if there is a dischai'ge, that solution of nitrate of silver may be used in addition ; not necessarily however, as he treated a number of cases * Buzzi — Eagiouamcnto siill' oftalinia pustolare contagiosa, quoted by Staderini, •' Annal di Ottalmol." '750 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. witliout it. This method, if tiie apparent facts on which it is attempted to found it are true (and I do not doubt but they are), may prove a most valuable one. I have used it in some cases, but I cannot say with much benefit. This has arisen in a great measure, I think, from the solutions being too weak, the eye being cajjable of bearing with advantage solutions of much greater strength than are now being used. Whatever may be the pathology of granular conjunctivitis, or whatever .stage it may have reached, or under whatever conditions it is found to exist, I have derived the best and most lasting benefits from a treatment first recommended by Prof. J. R. Wolfe, of Glasgow. This consists of scarification of the lids, massage, and the employment of syrup of tannin, in the proportion of two drachms of the tannin to an ounce of simple syrup. The parts are first painted with a 4 per cent, solution of cocaine as often as may be necessary, to abolish all sensibility. To take the upper lid as an example ; this is strongly everted, and the patient requested to keep the eye fixed in a downward direction. The extent to which the scarification is carried, will depend on the extent of the granular condition. Beginning at the lowest part, so that tlie haimorrhage Avill not interfere with the view, the incisions are to be carried along the horizontal axis of the lid as closely together as possible, over every part of the seat of morbid action. When there is considerable engorgement of the tissues, a thing not at all improbable, the incisions may be further extended, although no granulations are visible. When this has been accomplished the lids are closed, and massaged by the fingers of the operator. This the ]3atient is carefully instructed to do for the next few days. A lotion of weak boracic acid, to be used several times daily, is then oi'dered. After a few days' use, the syrup of tannin is substituted, and its instillation carried out according to the requirements of the case. Now, in considering this method a little in detail, its advantages will be more apparent. In the first place, I would remark, that scarification of the lids has never occupied that high position in 0])hthalmic surgery which its unquestionable advantage demands. My experience of it, for some years, has been considerable; and, if its good results were more widely known, they would be more highly appreciated. In the present instance, what does it accomplish? If carefully and properly done, the contents of every granule have a chance of escaping; hypertrophied papillae are unloaded, and their pernicious development is retarded; and finally, the conjunctival vessels participate in the depletion. The scarification may be repeated as often as may be necessary, the same routine treatment following it, already alluded to. I may say that I have practised this method for a long time, and increased experience only confirms my belief in its efficiency. It will be observed, that when contrasted with other methods, it has some recognised advantages. It Ulcerates the contents of the granules, that is undoubted ; and if commenced at an early stage of tlie disease, will certainly cure it, and leave the conjunctiva intact. The action of the tannic acid on the diseased conjunctiva is rapid and effectual, and without possessing any specific pro])erties, it is, to my mind, the best of all astringents. The limits of this short paper will only allow me to notice one of the Bccoiidary conditions that granular conjunctivitis gives rise to, viz., panuus, and this purely from an operative point of view. The ope}"ation A CASE OF SARCOMA OF THE EYELIDS. 751 of jieritomy for ])aiiims is so easy, and so simple in jierformance, and often so beneficial in its results, that it is surprising it is not more often resorted to. The operation itself, if we may dignify it by such a name, has, in reality, a much greater scope than would at first sight appear. It is not only that it is singulai'ly useful in itself, but it is a powerful adjunct to other treatment. It will often be found that a pannus, rebellious to medical measures, will not be cured by peritomy, but the effect of the j)eritomy will be that it may, and often does, 3'ield to treatment which was formerly used witliout avail. It may thus have a double function, and on that account its value is enhanced. Anaesthesia, general or local, is required for its performance, which I do in the following manner : — A cut is made with a pair of fine, blunt-pointed scissors, close to the cornea, through the conjunctiva and sub-conjunctival tissue. Into this a strabismus hook is introduced, and the structures put on the stretch. The scissors are inserted between the hook and the cornea, and follow it round, snipping the tissue close to the cornea till the circle is completed. The free conjunctiva is then seized with forceps, and a strip two and a half millimetres in width is cut off in the whole of its circumference. The only really essential part of the operation is, to see that the tissues have been quite removed from the sclerotic ; in fact, that the latter is completely bare. The immediate results are extremely variable — the cornea sometimes clearing quickly, and at other times very slowly. Such is a slight sketch of a disease and its treatment, that we are called upon daily to deal with, and which we deservedly look upon always with a feeling of doubt as to our capabilities of dealing with it. It is to be ho])ed that the day is not far distant when, with a better idea of its pathology and the various phases of its development, it will become more amenable to treatment. A CASE OF SARCOMA OF THE EYELIDS. By Odillo Maiieii, M.D., Ch. M. A maiden lady named S., aged 72 years, consulted me on May 10th, 1887, on account of a very peculiar condition of her eyelids. She was a thin feeble w-oman, who had spent a life of toil as a needlewoman, finding it not at all times easy to obtain more than the bare necessaries of life. She stated that frequently during the last two years her eyelids and cheeks had become so swollen that she had hardly been able to see out of her eyes ; and that after one of these attacks, five months previous to her consulting mc, the swelling of the eyelids did not altogether disappeai-, and had since gradually increased in size. Immediately under the right supra-orbital arch, and extending along its whole length, was a smooth tense semi-elastic growth composed of three lobes, which extended downwards into the eyelids between the skin and tarsal cartilage. The lower Ijorder of the growth was some- what arched, and did not extend to the edge of the eyelid. The tumour was about the size of a pigeon's egg. Neither bruit nor thrill could be 752 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. detected. Over the position of the right lachrymal sac was a .smooth hard tumour, about the size of a large pea ; and in the lower eyelid, a growth consisting of two lobes similar to that in the upper eyelid, but not quite so large. It extended fi"om the margin of the orbit almost to the edge of the lid. The skin was everywhere movable, and the growth in the upper lid was not continuous with that in the lower. The condition of the left upper and lower eyelids was similar to that of the right, but the growths were not quite so large. The patient for some months had been unable to see out of the right eye, and could only separate the eyelids of the left about a millimetre and a half. There was slight hypertrophy of the conjunctiva;. The eyeballs were normal. There was no proptosis, nor were the movements of the eyes in any way affected. The lymphatics, along the borders of the sterno-mastoids, and in front of the ears, were slightly enlarged. An aspirating needle, passed into the growths, proved them to be solid. Five months later (October 1887), the growths had increased in size, but the lymphatics appeared normal. She was unable to open the left eyelids at all, and was practically blind. As long as she could see to get about, I was averse to operating, on account of her age and feeble condition ; Ijut, as she was now practically blind, I operated on the left eyelids, freely removing the growths. I submitted them to Dr. M'Cormick, the Demonstrator of Histology at the Sydney University, for examination. The following was his report : — " The growth consists of large rounded granular cells, about one and a lialf times the diameter of a red blood corpuscle, embedded in a small amount of delicately-fibril- lated inter-cellular substance. It is very vasculai', and the blood-vessels lie in immediate relation to the cells of the part. It has got all the histological appearances of a large round-celled sarcoma." In April 1888, it was evident that there was a recurrence in the left eyelids, and as they were again closing, I operated on the right eyelids. In about ten days she left the Hospital, seeing well out of the eye which had been closed for sixteen months. There is now — December 1888 — recurrence in all four lids, and the left have almost closed. REMARKS ON OPHTHALMIC WORK IN WESTERN AUSTRALIA. By James William Hope, F.R.C.P. Ed., Fremantle, W.A. The soil along the sea-board of the Colony, where settlement chiefly exists, is mostly sandy and in large part lime-stone. Up to parallel 29° S. the rain falls chiefly from May to October, from there north it falls during the summer, consequently there is a large part of the year in all places which is very dry. During the summer months, breezes from the land occur from svmdown until aljout 10 a.m., then the wind comes from the sea, cooling the air, but still keeping it charged with dust ; flies are very troublesome in tlie summer. It is to these A-arious causes that diseases of the eye are principally due. REMARKS OX OPHTHALMIC WORK I\ WESTERN AUSTRALIA. 753 Ophthalmia. — This aH'ection, althougli general, is of greater severity ill some parts than in others, and the more serious attacks Iiappen in the north west. Many cases there have the acuteness of purulent ophthalmia, and \ea\e damage to sight not less than a specific form of that inflam- mation. These cases are locally spoken of as " blight," and are probably due to inoculation by flies and dust and dirt, conveyed by the breeze, and by the liands in wiping away perspiration. The attacks are accom- panied by pain, chemosis, purulent discharge, intolerance of light, and feverishness. A lamentable want of anxiety about the attack is often shown by parents, and the difficulty of getting medical treatment until lately caused many cases to run an unattended course, and left all the forms of sequehe that can result from svich cases, as nebula, leucoma, perfora- ting ulcers, with fusion of anterior parts of the eye, pannus, and granular lids. In most cases, however, there have been some attempts at treatment by those attacked, usually consisting in the api^lication of domestic or commercial eye lotions, and perhaps some golden ointment, but even these are used in such a superficial way as to be practically useless. Cases which present themselves for treatment are commonly those in which considerable damage has resulted, and are sad spectacles of ig-norance, apathy and disease. Milder attacks of ophthalmia are common throughout the Colony, and are frequently allowed to become chronic, although recourse is had to the ordinary eye lotions ; yet people are in ignorance that the lids become inflamed similarly to the ocular mucous membrane, and after the eyes have apparently become cured, they are surprised that there remains a gluing of the lids at night ; and in the day, lachrymation, with intolerance of light. It is only when the sight is impaired, and what is called a " scum " appears over the pupil, that assistance is sought. The cases almost invariably turn out to be granular lids, with perhaps pannus, and some ulceration of the cornea, caused by the friction of the rough lids ; the attendants or friends are surprised when the lid is turned up, and they see the red and brick-like roughness of the inner surface. Granular lids after some time usually produce in-growing eye-lashes, and one or the other or both will surely cause keratitis, ulceration of the cornea, or other damage. It is for this affection of the lids that most patients seek relief, and numerically it forms the chief work in diseases of the eye. To treat successfully, a great amount of patience and perseverance are required by sufferer and doctor, for it often takes months to get the lid smooth, in some cases as long as eighteen months ; nevertheless, my experience is that they can always be cured. I have never failed to effect a cure in the most obstinate case, if treatment be persevered with. Treatment. — I usually employ a 10 grain sol. argent, nit., sometimes a 15 grain solution, daily, at the same time using some ointment of the yellow oxide of mercury, or insufflation of calomel if nebulous cornea be present ; but if ulceration exists, eserine is the most effective drug. The great objection to the long continued use of the caustic solution is the pain it causes, and staining of sclerotic which I'esults, if care be not taken to prevent the lotion getting on to the eye. These drawbacks may be avoided by taking care to entirely evert the upper lid, then with the second finger draw up the lower lid so that the upper rests 2c 754 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. upon it. After applying the drug, absorb any surplus lotion by placing a small piece of good blotting-paper in contact with it, and it will be quite taken up. When the lid is released, very little pain or lachrymation will follow. Jequirity, as an auxiliary, is worthy of a place, but I have not had the good results from its use I expected. In some cases it sets up inflammation by one application, other cases tolerate it for many times, and upon lids that have had caustic applied it is almost inert. Where I have found some good from its use, is in protracted cases ; in these, after using it for a week, the re-application of the caustic solution is productive of more marked action. I consider it desirable to allow a few days to pass now and again without treatment, especially when the lid is nearly well, to see if any irritation is kept up by the applications. Pannus, the result of granular lids, will gradually disappear as the roughness of the lids is i^emoved, and its removal will be assisted by touching it with a mild caustic point two or three times a week. Ulcers of Cornea occur without any assignable cause, and in the acute form cause pain, redness, lachrymation, photophobia. Treatment, consisting of the application of eserine, a blister to temple, or the artificial leech, with a pad and bandage to keep the eye quiet, and supported with the administration of opium, will cure the patient. Clironic ulcers.— Scraping the sides and base will often liven up the parts, and the same local treatment will do good. Leucoma will also be benefited by following the same line of treatment as for chronic ulcers. Nebula may be removed in many cases by the continued use, locally, of calomel dusted on the eye, or ungt. hydrarg. ox. flav. Onyx, accompanying ophthalmia, will yield and disappear under the use of calomel and opium, or sulphide of calcium internally. Hypopion, like ulcers on the cornea, occurs without any other trouble of the eye, and frequently assumes a startling severity ; it is also sometimes associated with corneal ulcer. There is great pain, circum- corneal zone of redness, and often general haziness of the cornea, with a considerable collection of pus. By incising the eye, to remove the pus and relieve tension, great relief will follow. Eserine should be applied regularly, and the eye supported by a pad and bandage ; a blister to the temple, or the use of the artificial leech, with the adminis- tration internally of calomel and opium, or sulphide of calcium, will generally cure an eye that looks beyond improvement. In-growing Eyelashes of the upper lids, whether all or a few, can only be effectually cured by the removal of them all. Corneal Prominence, so as to prevent the lids covering it, is seen as the result of tliinning of anterior part of eye, with fusion of iris and cornea. Where it occurs in a man to whom time is of importance, the sight entirely lost, and who lives out of reach of medical help, I enucleate the eye ; but for women, I remove successive wedge-shaped pieces, which gradually brings the eye to its normal size, after which I tattoo a pupil. The latter treatment is also effectual in cases of conical cornea. Pterygium occurs very frequently, sometimes on one, sometimes on both eyes, growing usually from the nasal side towards the pupil, and in RKMAKKS 0\ OPHTHALMIC WOHK IN WKSTKltN AUSTRALIA. 100 time covering it, and so forming a complete barrier to vision. This condition is but rarely seen, but there are some who in the earlier days of the colony could not get treatment, and who have gone away to get the growth removed. I can merely reiterate an opinion I saw expressed in the AiistraldsiuH Medical Gazette, namely, that it attacks the exposed part of the eye where, from the heat of the atmosphere causing dryness, coupled with dust, hypertrophy of the mucous membrane is set up, and keeps on spreading. For treatment, T find transplanting into a wound of mucous membrane, after detaclunent, is not satisfactory, as it leaves an uncomfortable and unsightly lump, which remains for some time. I pi'efer to carefully dissect otl" the growth and remove it, applying to the stump either iodoform or solid argent, nit. ; sometimes they will recur, but the second removal is generally final. I have not heard any complaint that the removal causes any resulting scar, which interferes with the movements of the eye. When the growth is just forming, it can be made to disappear by applying the solid argent, nit. a fev/ times. Choroiditis and Choroido-Iritis I have seen to occur, when no cause nor history could be obtained or conjectured for the attack, but the fact that it followed upon working at a dry salt lake, where the heat and glare were intense. Cataract is, I think, more frequent than in cooler climates (though I have no statistics to guide me), from the number of cases that have come under my notice, considering our small population. The cause would be the heat and glare from our light sandy soil. Bunged Eves are common in summer, especially with children. They are due to the bite of a fly, which does not aj^pear to be of one particular sort, but rather one that causes the local trouble by puncturing the mucous membrane with a proboscis charged with some irritant, probably some decayed animal or vegetable matter. The lips, throat and nose are sometimes " bunged." When available, and before there is much swelling, if eucalyptus oil be rubbed vigorously on the eyelid, the swelling will go down ; when the swelling has taken place, olive oil instilled between eyelids will be comforting. Ophthalmia frequently follows these attacks. Aborigines. These never suli'er from ophthalmia, so far as I am able to ascertain, and I have had opportunities of examining their eyes in different districts, especially Rottnest penal settlement, where men from all parts of the colony are located ; they never seem to have any impair- ment of sight from disease. AVhen the sight is damaged or lost, it is usually the result of accident. They have bushy eyebrows and long lashes. 2c -2 756 INTERCOLOXIAL iMEDICAL CONGRESS OF AUSTRALASIA. THE TREATMENT OF CHRONIC CATARRH OF THE MIDDLE EAR. By James W. Barrett, M.D., M.S., F.R.CS. Eng. Assistant Siirgeou to the Victorian Eye and Ear Hospital, and Demonstrator and Examiner in Physiology in the University of Melbourne. It is in the first instance necessary that I shall clearly indicate what I mean by Chronic Catan-h of the Middle Ear, or, as many term jt, Chronic Non-suppurative Inflammation of the Middle Ear. In the great majoi'ity of cases, the appearance of the membrana tympani indicates the existence of the disease usually described by these names. It is sunken, thickened, atrophied, the bright spot is altered, or in some way the appearance deviates from that of the healthy membrane. The watch and conversation hearing is deficient, and in advanced cases the tuning fork test gives a more or less minus result. Abovit this class of case, there can be no doubt; but in a fair number of cases the membrane looks normal, yet the watch hearing is greatly deficient, and inflation by Politzer's method improves but slightly. This class of case may be fairly grouped with the former. It is however necessary to exclude from the categoiy two classes of cases : — Firstly, those of Eustachian obstruction. These cases, though certainly not very numerous, seem to have passed out of tlie sight of some modern writers, who believe by implication that deafness cannot occur fi'om simple obstruction of the tube uncomjDlicated with disease of the tympanum. Yet the explanation of a proportion of the cases of deafness met with in common cold, would appear to be the obstruction caused by catarrh of the throat and of a portion of the Eustachian tube; in these cases, the membrane appears perfectly normal. A similar condition of things (but which is usually complicated with indrawing of the membrane, on account of the chronic nature of the disease) is met with in children who suffer from naso-pharyngeal catarrh. In both sets of cases, inflation by Politzer's method almost completely restores the hearing instantly. For such cases, it seems to me, the term " Eustachian obstruction " is justly applicable. In other cases arising from cold, the tympanum is affected, and inflation does not at once relieve. I have therefore excluded from consideration in this paper the cases of Eustachian obstruction. Had I included them, my percentage of complete recoveries woidd have been greater. Another class of case which I have excluded occurs mostly in old peoi^le. Their watch-hearing is very defective, and the tuning-fork test gives a very negative result, and this often with signs of catarrh of the drum. One is uncertain how far the deafness is due to senile degene- rations taking place in the cochlea, or in the joints between the ossicles, or how far to catarrh of the drum — which is primary, or which is secondary ? I refer to these cases in my note-book as senile catarrh of the middle ear. They are also excluded from consideration, or the pcr- centairc of recoveries would have been diminished. TREATMENT OF CHRONIC CATARRH OP THE MIDDLE EAR. 757 To give Jin idea of tlie gravity of chronic catarrh of tlie middle ear in this country, I append the result of the examination of Hfty hopelessly deaf ears. By this, I understand cases in wliich, if under fifty years of age, the watch could only be heard on contact; if over that age, the conversation-liearing was reduced to nil, i.e., persons incapable of following any conversation, and in all of which treatment was useless. Of tlie fifty deaf ears — 25, or 50 per cent., were caused by chronic catarrh of the drum. 10, or 20 per cent., were caused by a combination of chronic catarrh and impairment of the nervous apparatus, it being uncertain which was primary and which Avas secondary. 1, or 2 per cent., was caused by disease of the labyrinth. 2, or 4 per cent., were congenital. Exact cause of deafness unknown. 2, or 4 per cent., were caused by intra-uterine catarrh of the middle ear. 5, or 10 per cent., were caused by acute catarrh of the middle ear. 5, or 10 per cent., were caused by chronic suppurative catarrh of the middle ear. Probably, then, over lialf the cases of deafness were due to chronic- catarrh of tlie middle ear. Let us take, then, a typical case of chronic catan-h of the middle ear, in which there is indrawing of the membrane, possibly redness of the malleus, and some affection of the naso-pharynx. What treatment is usually adopted 1 Nearly all aurists, in spite of apparent differences, ideally adopt a similar treatment. They attack the morbid condition of the throat by the use of gargles, the nasal douche (in spite of the accidents which have been attributed to it), or, what is more efficacious than either, alkaline and antiseptic sprays, and the use of various local applications, including the galvano-cautery. They treat the ear itself by systematic inflations, either by Politzer's method, by the catheter, or by Valsalva's method, and many inject vapours into the tympanum. Most of them, however, .seem to have given up all vapours, except that of chloride of ammonium. They all seem to agree, that it is a disease which can be rarely cured, but which tends to become steadily worse as the patient grows older; but it would seem that the one circumstance in their treatment, which is essential, is this systematic inflation. There seems no doubt that in many cases a certain amount of improvement is produced ; the catarrli is got rid of, the hearing remains stationary for some time, and the patient passes away from treatment. A cold is then caught, a sliglit inflannnation of the drum follows, and away goes the improvement in the hearing and some additional liearing ■as well. No treatmeiit is adopted, and the hearing never returns to its 758 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. old condition. A patient suft'ering fi'om this disease must be informed that, to a greater or lesser extent, he must place himself under the treatment of an aurist for the rest of his life. He should present him- self for examination at least once in every six months whilst the disease is stationary. At such a visit the hearing should be accurately tested, and the result compared witli that of the last examination. In addition, if at any time he catches cold, or notices that his hearing is manifestly worse, he should immediately seek advice. The treatment which I have adopted has been as follows : — (1) The treatment of the catarrh of the pharynx which is often present. I usually inquire carefully into the habits of the individual, and endeavour to obviate the liability to catarrh from which so many people who follow sedentary occupations sutler. Errors of digestion play a part in its production, and especially in women should the excessive tea-drinking be cliecked. Regular bathing and open air exercise are recommended, and patients are cautioned against two errors into which people are very apt to fall in this country — that of o^•er clothing and of under clothing. This latter piece of advice is especially necessary, on account of the extraordinary variations of temperature in Melbourne. Locally, I use saline douches, sprays, and other applications (including the galvano-cautery) in the treatment of the naso-pharynx. (2) With regard to the ear itself, I act on the following principles : — • Redness of the handle of the malleus indicates active change [vide Paper in this volume) in the middle ear, and calls for blistering, protection from cold air, and very careful Politzerisation. In nearly all cases in which the aftection is not sub-acute or acute, Politzerisation seems to be indicated, and it is my custom to practise it, when called for, twice or three times a week for five or six weeks. In the intervals between the visits, the patients are instructed to practise the method of Valsalva from two to four times a day, and massage of the ears for one minute a day. Of late, I have been adopting the method of alternate inflation and exhaustion by the Ward-Cousens apparatus in place of the Politzer method, and with rather better results. I do not now use the vapour of chloride of ammonium, because of the difficulty in getting patients to use the apparatus. The whole of the local treatment may be regarded as liaving for its object the preservation of the mobility of the ossicles and membrane, and to obviate the consequences of adhesions and air exhavistion. It seems to be partly analagous to tlie effect of passive motion on a chronic inflammation of a joint. It lias never fallen to my lot to see any injurious consequences follow tlie use of the nasal douche, the Politzer or Valsaha methods employed in the manner indicated. Subjoined is a synopsis of a taVnilar statement of the cases of forty- eight patients treated, and about wliom I hiive taken careful notes. The tal)le (not given here on account of ])ressure of space) sliows the age of the patients, tlie duration of time which they believed they had surt'ered before consulting me, the distance at which they could hear the watch Ijefore treatment was begun, the duration of treatment, and TREATMENT OF CIIKONIC CATARRH OF THE MIDDLE EAR. 759 the distance at ■which they could heai' the watch when treatment was discontinued. The figures indicate a less favourable result than that which should have been obtained, since many of the patients dis- continued treatment before I wished them to. Any one who can hear the watch I employ at ten inches can hear conversation fairly well. People aged 25 can liear it at about one hundred inches distant; from one hundred to ten inches I regard as the range of their surplus hearing. They do not usually complain till the hearing is less than ten inches ; then they cannot follow conversation, and they seek advice. The time occupied in this reduction is usually years, and it is this loss of time which makes the treatment of this disease so unsatisfactory. Those who could hear the watch at a distance of more than fifteen or sixteen inches are x'eported as cured. Analysis of the table shows that of the ninety-one ears (forty-eight cases) — 10, or 11 per cent, were cured. 27, or 30 per cent, were absolvitely unimproved. 54, or 60 per cent, were impi'oved. Taking the first thirty-seven cases, those in which the treatment was usually continued for a fair length of time, of the seventy-two ears treated — 8, or 11 per cent, were cured. 23, or 32 per cent, were absolutely unimproved. 41, or 57 per cent, were improved. Taking the first twenty-thi^ee cases, that is all those under 25 years of age, we find that of the forty-six ears treated — 6, or 13 per cent, were cured. 13, or 29 per cent, were absolutely unimproved; whilst 27, or 58 per cent, were improved. Taking the 24th to the 37th cases, that is the cases between 25 and 57 years of age, we find that of the twenty-six ears treated — 2, or 8 per cent, were cured. 10, or 35 per cent, were absolutely unimproved ; whilst 14, or 53 per cent, were improved. From these tables, it seems that the number of cases of recover}- is somewhat gi*eater, and the number of unimproved cases is somewhat smaller, in those under 25 years of age, than in those over 25 years of age. Wliere the membrane is much sunken, where the patient is young, or where there is redness of the handle of the malleus, considerable improvement may usually be expected as a result of treatment. Where the membrane is not sunken, but is pale or opaque, where the disease is long-standing, and the patient advanced in years, improv^ement is usually slight; the disease is stationary, and we have to deal, not with an active disease, but with the consequences of former disease. Yet in a fair number of cases, it seems impossible to even conjecture whether improve- uient can be effected oi' not. Until some better method is devised for obtaining information as to tlie condition of the interior of the tympanum, the business of the aurist will continue to be as relatively inexact as it is at present. 760 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Table (Roosa) showing the Results of Treatment of Chronic Nonsuppurative Inflammation of the Middle Ear : — Reporter. No. OF Cases. Cured. Improved. Unimproved. Un- known Spencer * (St. Louis) 56 6=16| percent, of those actu- ally treated 18=50 per cent. 10=27 percent. 20 Schwartz t • . (Halle) 230 30=20 per cent. 94=60 per cent. 30=20 per cent. 75 Gruber \ (Vienna) 187 38=32 per cent. 61=60 percent. 9 = 9 per cent. 84 Eoosa § (New York) 514 23=4^ per cent. 160=31 per < 171=34 per cent. cent. 159 Barrett (Melbourne) 95 cases in all 48 actually treated 10= 11 per cent, of the 91 ears (48 cases) treated 54=62 percent, of the 91 ears (48 cases) treated 27 = 30 percent, of the 91 ears (48 cases) treated 47 cases * Reprint from St. Louis Medical Journal. t Archiv. ftir Ohrenheilkuude, bd. 1, v. passim. X Monatsclirift fur Olireuheilkiuide, bd. 1, iv. passim. § "On Diseases of the Ear," Lewis, London, 1S79. Dr. Iredell (Melbourne) said that tests for hearing were unsatis- factory, and the watch test was no exception to the rule ; still, it aiforded some indication of the hearing power. In cases of chronic catarrh, where no active change was going on, he had found cases usually became worse under any circumstances, perhaps more rapidly when treated. He objected to the Valsalva method. It was more powerful than the Politzer method, and liable to produce flaccidity of the membrane. He had never seen any harm result from the use of the nasal douche. He agreed with Dr. Barrett, tliat where redness of the malleus existed — an active condition — some improvement can usiially be effected. This redness can rapidly be removed by instilling vapour of chloroform into the drum. He thought that, in old cases, the nervous apparatus is affected secondarily. Dr. T. K. Hamilton (South Australia) said that, in many old sclerosed cases, passive motion was useful. He used hypodermic injections of pilocarpine in cases of labyrinthine disease, and also in chronic catarrh ; it tended to produce absorption. He did not use the nasal douche, but preferred sprays in the treatment of the naso- pharynx. He believed that the treatment by multiple incision of the membrane was hopeful in some cases. It was possible also, that something might be done in the future by tlie local application of electricity to the pharynx and to the Eustachian orifices. He objected to the use of the Valsalva method, because of the congestion produced by the expiratory effort. Dr. Brady (Sydney) had found great benefit in the treatment of the pharynx, by removing the liypertropliied tissue with the cutting forceps. OPTIC NEURITIS FOLLOWING EXPOSURE TO HEAT. 761 NOTES ON A CASE OF OPTIC NEURITIS, FOLLOWING EXPOSURE TO HEAT. By H, LiNDO Ferguson, F.R.C.S.L Lecturer en Ophthalmology in the Otago University. Leber, in liis article in "Graefe and Saeniiscli's Handbuch," mentions ill half a dozen Avords that optic neuritis may follow sunstroke ; and Professor Williams, of Harvard University, in his book on " Diseases of the Eye," says: — "Insolation of the head may cause pailial amaurosis, the prognosis depending on the degree in which the central nervous organs are affected, and the recovery being slow." Dr. Wood, in " Pepper's System of Medicine," refers to a case of chronic meningitis following sunstroke, with diplopia and some blurring of the optic discs, but gives no complete details as to vision or field. AVith these three exceptions, T have failed to find any reference to the condition in such works on Ophthalmology as I have at my command ; and, as the condition is not referred to in the indexes to the sixteen volumes of "Knapp's Archives," which give a very complete periscope of ophthalmic literature from 1869 up to the present time, I may conclude that optic neuritis, as a result of exposure to heat, very rarely comes under the notice of ophthalmic sui'geons. The only published case I have come across is quoted in the British Medical Journal, July 7, 1888, from the JSpao York Medical Record. Dr. Tuttle of Jefterson was the sufferer, and reports that in June 1863 he had sunstroke, and was quite blind till the third day. Vision slowly improved, but the fields of vision were so much contracted, that he felt as if he were looking through two gimlet holes. Vision, twenty -five years later, is still very imperfect, and the fields are much contracted, witli complete night blindness. The case is unfortunately very incomplete, as there is no reference to the ophthalmoscopic appearances ; and though the present condition of the vision is consistent with the assumption that there is atrophy of the optic nerves, the absence of examination of the fundus in the early part of the case leaves us in doubt as to whether the visual troubles w-ere the effect of injury to the visual centres, or of optic neuritis, secondary to the cerebral lesion. I have seen two cases of optic nerve lesion — one of old standing, in which the patient attributed his condition to sunstroke, but in which the history was very imperfect; and one recent case, the notes of which I propose to place before you. In the first case, a seaman of over middle age applied to me at the out-patient room of the Richmond Hospital, Dublin, during the summer of 1880. He stated that two and a half years previously he was employed in a trading schooner in the South Seas, and exposed to very intense heat. He suffered from very severe headache, and lay on deck at night for coolness. On the third day his sight failed, which he attributed to lying on deck in the moonlight, though he blamed the insolation for causing him to do so. At the end of his trip he w'as admitted blind into the Dunedin Hospital, where he was treated for many weeks, during which he still suffered excruciating pains in the head. He had been discliarged, free from pain, but with bare 762 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. perception of light, and had somehow found his way home to Dublin. He had intense post-neuritic atrophy of both optic nerves, and l^are perception of light in the left eye. Treatment was unavailing. Only having seen ophthalmic work in tempei-ate climates, I inquired as to other likely causes without eliciting any, and finally passed the case over as puzzling, iDut hopeless. Unfortunately, I have no record of his name, so that I have been unable to trace him in the hospital records here. The history of the case makes the suggestion, that the neuritis was due to insolation, at all events possible ; but though he denied ever having had syphilis, the possibility of a specific cause in a seafaring man is too considerable for the case to be accepted as a wholly satisfactory one. The second case is a recent one, and all other causes were carefully excluded, or have been excluded by the subsequent history : — Miss K. ]M., aged 5, living in Canterbury, was brought to the study on March 11th, 1884, with the following history : — Slie was in perfectly good healtli till the third day of a hot wind, thirteen days before her visit. The nursery was very hot, and she was constantly running in and out through the verandah into the garden in the heat. On this day she complained of a pain behind the right ear, which lasted three days. On the fourth day her sight was noticed to be defective, and gradually failed for four days, since when it had been stationary. She had had no treatment except a vermifuge. She was the eldest of four healthy children, and the family history was good. When seen, V Oc. Dex.= fingers at 0"5 millimetres; Oc. Sin. = mot. hand. With the ophthalmoscope the right disc was seen to be blurred, the retinal veins large and the arteries small and indistinct. The left disc was swollen on its nasal side. A diagnosis was made of descending optic neuritis, secondaiy to meningitis, due to exposure to heat. A fairly favourable prognosis was given, and she was put on the iodide and bromide of potassium, and also given two grain doses of pulv. hyd. c. cret. thrice daily. She was freely heurtelouped on both temples, and kept in the dark for the subsequent twenty-four hours. On March 13. — V = mot. hand Oc. Utr., and the discs were more swollen. Slie was ordered inunctions of ung. hyd. gr. xv thrice daily, a,nd given pil. col. co. and pil. rhei. co. aa. gr. v. On March 14. — V = F 0*5 millimetres Oc. Dex., mot. hand Oc. Sin., and she had numbness and loss of power in the right hand. The inunctions were pushed. The following day slie had more power over tlie right hand, but had had spasmodic twitchings of her throat during sleep. On March 16. — V Oc. Dex. - F 1"5 millimeti'es, Oc. Sin. mot. hand. Had had severe twitchings and jumping of legs during sleep. She was ordered a draught of bromide of potassium and chloral if twitchings should occur during the night. During the three following days the swelling of the discs increased, in spite of the renewed use of the artificial leech. She was very restless and delirious at niglit, but would sleep heavily from 3 a.m. till 1 p.m., or later. In the restless stages, she rolled her head continually from side to side. OPTIC NEUHITIS FOLLOWIN'G EXPOSURE TO HEAT. 76S On March 21 she was looking well, and the symptoms of nei'vo irritation were less. Her gums were not touched, though she was having 3 j of ung. hyd. rubbed in daily. On March 23. — V Oc. Dex. had risen to F 3-5 millimetres; but on the 25th, she was complaining of pain in the right mastoid, and had slept from 3 a.m. till 5 p.m. The vision had gone down to F 2-5 milli- metres Oc. Dex. Oc. Sin. V = P light. March 26. — There was more mastoid pain, and V had fallen to F 1 millimetre Oc. Dex. The left disc was much paler and shai'per in outline than before; temp, normal. Ordered half a minim ol. crotonis in 3 ij ol. ricini, and gr. xx of bromide of potassium every four hours. The following day she had been much purged by the croton oil, and had slept very little, but the ^■ision was a shade better. Dr. Batchelor saw the child later in the day with me, with reference to the nature of the cerebral lesion. He concurred in the existence of meningitis of the base, and in the treatment, which was continued. After two quiet nights, V on the 29th was F 1-5 millimetres Oc. Dex., which was impi'oved to F 2 millimeti'es by the use of a continuous current for three minutes. The discs looked white, and the arteries very small. The inunctions were stopped. By April 2, Y had risen to F 3 millimetres Oc. Dex., F. 1-25 milli- metres Oc. Sin. ; but on the 4th, there was fresh occipital headache, and V fell to F 1 millimetre Oc. Utr. She had no severe headache later than the night of the 5th, and from the 7th the vision began to improve steadily. The constant current was used at each visit to the study, and always produced some improvement, which was generally retained. On the 11th, she was ordered Kirby's phosphorus, quinine and nux vomica pills, her vision then being F 2 millimetres Oc. Dex., F 1-5 millimetres Oc. Sin. Both discs very white. On the 20th, V was ^ Oc. Dex. and F 2 millimeti'es Oc. Sin.; and on May 7th, V was -^^, and letters J 1 better, and F 5-5 millimetres Oc. Sin. She was then allowed to return home, with directions to continue the pho.sphorus pills. She made steady pi'ogress, and on October 31 Y was y\ Oc. Dex., and y\ letters Oc. Sin. and Prox. J 1 Oc. Utr. easily. The discs were white and sharply defined, but the arteries were larger than before. All treatment was then stopped, but she was ordered to return to the pills from time to time whenever she did not seem thox'oughly strong and well. In December 1887, Y was f letters Oc. Dex., § letters Oc. Sin., and the nerves remained about the same as when last seen. On October 12, 1888, Y was f letters Oc. Dex., f Oc. Sin., and Prox. J 1 Oc. Utr. The fields of vision were normal, and the only anomaly of function I could detect was, that she seemed slow to recog- nise retinal impressions. Both discs were very sharp and white, and the arteries small. Her general health is perfect, aiid both her physical and mental development are above the average for her age. The fact of the child's physical and mental health being good four and a half years after the attack, and the absence of any cerebral symptoms in the mean time, except an occasional headache on a hot- wind day, practically put the existence of a cerebral tumour out of the 764 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. question ; and of the family history being good, except that the mother is neurotic, there is absolutely no doubt. The only explanation of the neuritis that occurs to me is the diagnosis I made in March 1884, and that insolation is not recognised as a cause by the majority of authors does not preclude the possibility of its producing this effect. Most authors who wi'ite on ophthalmic subjects live and practise in tempei'ate climates ; but insolation is fairly common in many of the lai'ge American centres, and occurs sufficiently often in London and the large continental cities to make it likely that, if optic neuritis were a frequent complication, the fact would have been recorded. Since treating this case, I have kept a special watch on the reports of the Madras Branch of the British Medical Association, to see if Brigade- Surgeon Sibthorpe, or any of his colleagues, have noticed similar instances, but without success. Possibly, the natives are not very susceptible to heat, and the Europeans take sufficient precautions against it. It appears to me that the most likely soil for the observation of the conditions likely to cause ocular troubles in connection with insolation is Australia, wliere iiitense heat is far more common and universal than either here or at home, and where the tendency in the rising generation to develop tlie neurotic strain, common alike to America and the colonies, has had a longer time to show itself than in New Zealand. It is in the hope tliat these notes may call forth similar observations, if any exist, that I have ventured to bring them forward. A CASE OF CEREBELLAR ABSCESS, UNSUCCESSFULLY TREATED BY TREPHINING. By H. LiNDO Ferguson, F.R. C.S.I. Ophthahuic and Aural Surgeon to the Dunedin HosiDital. Lecturer on Oplithahnology in the University of Otago. E. C, aged 17, presented himself on July 21, 1888, with the following history :— He had suffered from otorrhcea from the right ear, of nine years' standing, following scarlatina. The dischai'ge ceased at intervals, to give way to naastoid pain and tenderness. He had been in the Dunedin Hospital three years previously under my care for mastoiditis, but recovei'ed after a large Wilde's incision had been made. He had not since liad any severe attack until the one for wliich he sought advice. Tlie discharge Jiad ceased four days previously, and he had since suifered from severe headache and mastoid pain. The memljrana tympani was gone, and the mucous membrane of the middle ear was much swollen and glazed, but showed hardly any discharge. It was excessively tender, and he could hardly bear it to be touched with cotton wool. There was great pain and tenderness in the mastoid region, which showed the scar of the old incision. Syringing the ear caused considerable giddiness, so he was given no lotion, but CEREBELLAR ABSCESS UNSUCCESSFULLY TREATED BY TREPIIIXING. 765 was ordered constant poultices over the ear and mastoid, and told to i^o into the hospital at once. At this time the boy was looking very ill, and he had been shivering. His tongue was thickly furred, and the ])0wels wei'e contincd, but his temperature was normal, and his pulse about 80. For some reason, he did not go into the hospital till the 23rd, two days later, when his condition was much about the same. He was given a purgative, and put on the iodide and bromide of potassium, and the poultices were continued, a slight discharge from the ear having been established. The mastoid tenderness was less, and there was no putfiness about the ear. On the morning of the 25th, his temperature ran up to 103°, without marked rigor, falling in the evening to 100°, but he expressed himself as feeling better and in less pain. The following day his temperature rose to 101°, falling to 100° after he had been given gr. iv. of calomel witli gr. V. of sod. bicarb., and it never rose abo^■e this point till the end of the case. The constipation continued, and on the 28th, he was given a saline purgative, which seemed to make his head more comfortable. He did not complain much of pain, but moved his head slowly as if motion hurt him. His genei'al condition otherwise seemed better. There was no loss of power on the left side, and he answered intelligently when spoken to. On the 29th, he had occasional attacks of drowsiness, and at 3 a.m. on the morning of the 30th, he woke with severe mastoid pain, for which Dr. Fleming, the House Surgeon, was called and gave gr. v. of calomel by the mouth. The pain shoi'tly afterwards ceased, but he became comatose, and was only capable of being partially roused at 9 a.m. This slight improvement at 9 o'clock coincided with the establishment of a free foetid discharge from the ear, and his temperature was then only 99°. At 11.30, the free fojtid discharge from the ear continued, and he was lying in a state of semi-coma. Both pupils were contracted, and both optic discs were intensely red and congested. He groaned slightly on the head being moved ; but from his condition, no loss of power on the left side could be detected, to give any clue to the seat of the abscess. His respiration was 18, and stertorous. Pulse 76, and good. At a consultation of the Staft' two hours later, it was thought that there was less resistance to passive movement on the left side than on the right ; but his condition of coma was deeper, and he no longer groaned when the head was moved. The discharge from the ear had lessened considerably. In the absence of any paralytic symptoms, the motor ai-ea could be excluded as the seat of the lesion ; and it was decided that the best chance of reaching the abscess lay in opening the temporo-sphenoidal lobe. While he was being chloroformed, a gush of nearly half an ounce of fearfully foetid pus came from the ear, and the meatus was immediately plugged, lest by the escape of the matter the abscess cavity should be missed, and the chance of establisliing satisfactory drainage lost. A spot three-quarters of an inch above, and one and a half inches behind the axis of the meatus, which had been the most tender spot on percussion, was selected as the centre of the opening. A curved horizontal incision, with its convexity downwards, was made below this 766 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. spot down to the bone, and a vertical incision meeting the first one at its centre. Tlie periosteum was raised with the flaps, showing the bone below healthy, and an inch disc of bone was removed at the chosen spot. Some little difficulty was experienced from the lower edge of the trephine cutting tlu'ough the thick bone at the head of the mastoid, so that the incision down to the dura mater being complete elsewhere, the disc was still held in place. When it was elevated, the dura mater was seen to be light green in colour, and thickly infllti'ated with matter ; but wlien it was divided, the brain substance below seemed perfectly healthy. As a few drops of matter welled up from the anterior lower part of the opening, between the dui'a mater and the bone, a three- quarter inch disc was removed farther forward, the pin of the trephine being placed about an eightli of an inch in front of the edge of the first opening. When this was removed, the dura mater underneath was found to be healthy, and the pui'ulent meningitis was found at the post-mortem to be confined to the area exposed by the fii^st opening. A needle was then passed into the brain in six or seven directions up to a depth of three inches witliout finding matter. A probe passed downwards slid in along the surface of the tentorium, and it was not considered wise to pass a needle down for fear of entering the lateral sinus. Further attempts were abandoned. A drainage tube was left to the dura mater, and the wound was closed. After tlie operation, his pulse was 76 and his respiration 17 and irregular, but not so stertorous as early in the day. At 5 p.m. his pulse was 100 and his respirations were 22, shallower, but more regular. His temperature had fallen to 98°, and he answered rationally when spoken to, and recognised his mother. The following day his condition was about the same, but on August 1 he roused up and asked for beef-tea. This improvement coincided with fresh discharge from the ear. On the 2nd, he relapsed into a condition of deep coma, and died during the night. At the post-mortein examination made next day, a patch of purulent meningitis Avas found, almost exactly corresponding in extent with the first disc of bone removed. The wound had healed by first intention, except where the drainage tube projected at the lower angle. An abscess, the size of a small egg, occupied the front of the right lobe of the cerebellum, and connnunicated with the ear by the passage seen in the specimen. It is difficult, looking at the specimen, to understand how the boy escaped pyaemia, as the channel through the bone opens directly into the groove for the lateral sinus, and the passage by which the matter escaped lifted the walls of the sinus and passed below it. Had any attempt been made to pass a needle thi^ough the tentorium into the cerebellum, it would have pierced the sinus, and resulted in emptying the abscess into the vessel. There is no need for me to do more than refer to the specimen, which speaks for itself ; but I regret tliat, as I was not present when it was removed, only a small portion of the trephine opening was preserved. The temperature chart is of interest in connection with Dr. Bristowe's observatioii that, tliough the temperature is usually normal in cerebral abscess, there is generally fever when the lateral sinus is involved. Though this remark lias been made with reference to cerebral abscess, I am not aware of any series of observations as to tlie temperature in A CASE OF CEREBELLAR ABSCESS UNSUCCESSFULLY TREATED BY TREPH?NiNG Bjr KLindo lergusoa, ERCSJ. DATE July Aug. 23 24 25 26 27 28 29 30 31 1 2 [06° 105' 104' 103' 102" lor 100*' 99 98 97 PULSE ^ RESPN. ^ SKIN TONGUE BOWELS URINE M:E M.E M.E M.E m:£ m:e: m:e m:e ME ivi;e m:£ A ■ \: ';' J \/ 1 ■ ■ V f . V Y-- f-9^ SjH ^^ . • w w >-^ '; ^ v '■ ; 76 80 76 68 76 74 72 T2. 76 ICO 80 84 76 8Z /7 22 2^ 2^ 2^ It Dry 3lJ throu^/j Thickly furreo/ s/I throug/f 0/3 ly acted 3fter Meaf/'c/nes nofed in case N/'g/} coloured Lithstes COXfiKNITAL CYST OP THE LOWER EYELID. 767 cerebellar abscess ; and from the close relations of the cerebellum and lateral sinus, it must always be a matter of difficulty to say whether the high temperature is due to cerebellar lesion, or to implication of the sinus. The case only throws a negative light on cerebral surgery, by show- ing once more that there are no localising symptoms in cerebellar abscess ; and coi'roborating the observations of others, that the seat of most intense pain is not a reliable guide to the situation of the lesion. One very interesting observation was made on section of the brain — that the needle punctures had caused no irritation and left no trace, wliich encourages exploi'ation in doubtful cases. The literature on the subject of cei'ebral surgery is as yet so limited, that even an unsuccess- ful case is of interest, and I have tlierefore felt emboldened to bring this one before the Congress. A CASE OF CONGENITAL CYST OF THE LOWER EYELID, WITH MICROPHTHALMOS. By W. Odillo Maiier, M.D., Ch. M. In June 1887, an infant was brought to me by its mother, who was anxious to ascertain whether the child's left eye had been "burst at l)irth." My attention was at once drawn to a smooth tense tumour in the left lower lid, about the size of a cherry. The skin over it was of a bluish tinge, and fairly movable. The eyelids were well developed, but the upper one sank inwards as though tlie eyeball was absent. The left half of the frontal bone was ill-developed. On separating the eyelids, a cavity lined with conjunctiva came into view, but nothing resembling an eyeball could be seen. As the child had an imperforate anus, and evidently could not live long, I refrained from administering an anajsthetic to facilitate the examination. A few days later, Dr. Crago (to whom 1 am indebted for the opportunity of examining this case) sent me word the child was dead, and I was then able to make a thorough examination. On separating the eyelids, the cyst in the lower lid was seen to extend along the floor of the orbit. At the bottom of the cavity, which was lined with conjunctiva, was seen the small cornea (about a millimetre in diameter) of a rudimentary eye. The rudimentary eye, which I incised, was about the size of a large pea. The cyst contained about a drachm of thin yellowish-green fluid. There was a coloboma of the iris of the other «ye. 768 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. A CASE OF GLAUCOMA, IN WHICH IRIDECTOMY APPEARED TO BE HURTFUL. By James T. Rudall, F.R.C.S. If the object of this communication were to discuss, ever so briefly, the real value of iridectomy in glaucoma, while I should by no means claim for the operation a universal success, it would be possible to refer to cases in my own practice where it has produced beneficial resvilts, sometimes, indeed, to a degree unlooked for, if not almost incredible. And probably, thus far, my experience is not widely different from that of many other practitioners in this department of surgery. For, although Von Graef e's brilliant discovery was first met, in some quarters, by strenvious opposition, time has shown that iridectomy in glaucoma is one of the great advances in modern ophthalmic practice. But, this being admitted, it by no means follows that we need no further study of glaucoma and its management; and since it is possible sometimes to learn from failure as well as from success, I now desire briefly to record the following case, which caused me unusual regret and disapj)ointment : — A single woman, forty years of age, was sent by a medical friend for my advice on March 16, 1888. According to her statement, about two years ago she lost the sight of the left eye, which was now found to be without perception of light; to have the pupil so much dilated that the ii'is was a mere atrophied ring; to have staphylomatous bulgings of the sclera at the outer margin of the ciliary zone in the lower and outer quadi'ant, and likewise to be affected with secondary cataract. This eye also had T + 2. She said further, that three days ago the sight of the right eye became misty, she had pain in the eye and orl^ital circum- ference, and she saw rainbow colours around the candle flame. On examination there was little, if any, conjunctival or scleral injection; the pupil was not dilated, but the iris was thrust forwards, and there was increased tension — T+ 1. Vision was nearly fg, and some letters of 2 Snellen could be made out at 12 inches. The fundus could not be illuminated by the ophthalmoscope. Eserine drops (gr. iij to ^j) were ordered to be instilled four times in the twenty -four hours. March 18. — Vision was reduced to y%% T + 2. The anterior chamber Avas almost obliterated, the iris lying nearly in contact with the cornea. I now considei'ed that, having regard to tlie previous loss of sight in the left eye, and the rapidly failing vision in the one (right) newly attacked, iridectomy on the latter was urgently demanded. The patient being in poor circumstances, I took her into the hospital, and performed an upward iridectomy on March 20. As it would not have been possible to use the ordinary lance knife witliout great risk of wounding both iris and lens, I employed in the operation a very narrow knife (De Wecker's), and with it I was able to make a satisfactory, though slow, upward section of the coi^nea. In other respects also, the completion of the operation answered my expectations ; there was, however, some bleeding from the cut iris. She was for a time relieved from pain, but when we opened the eye two days afterwards, vision was found to lie quite abolished. Soon, the EXCISIOX OF A SU^PU1^ATINCJ KYEBALL. 769 tension, whicli liad been temporarily reduced by the iridectomy, became as high as before, and pain also returned. Subsequently the scar became cystoid, and although sight was irrecoverably lost, I performed a second iridectomy (downwards), in the hope of relieving pain and tension. This proceeding liad \-ery little immediate eftect, and she had to remain under supervision for a considerable period. I confess myself unable to explain satisfactorily why in this instance the operation of iridectomy pro\ed futile, if note\en injurious; for it seemed improbable that the disease, left to itself, would cause absolute loss of perception of light in so shoi't a time as four or five days. DEATH FROM SEPTIC MENINGITIS, FOLLOWING EXCISION OF A SUPPURATING EYEBALL. By James T. Rudall, F.R.C.S. In more than twenty years of my practice, one case only had been fatal after excision of the eyeball ; and as was proved both by the symptoms and by a post-mortem examination, death in that instance had nothing to do with the eye affection, or the enucleation of the globe which was performed for it. The orbit and the cranial contents were found to be sound and healthy. The cause of death was extensive suppuration and sloughing of the connective tissue outside the lower part of the bowels, produced by the injection of a turpentine enema. The case was published at the time in the Australimi Medical Journal, and the only supplementary statement I have here to make is that, whereas when it was reported I was inclined to hold the nurse blame- less, information subsequently obtained has led me to attribute the death to gross cai^elessness in the administration of the enema. On August 21, 1886, a medical gentleman of my acquaintance requested me to meet him in consultation on Mr. , living about twenty-five miles from Melbourne. The patient was a fairly healthy man between 30 and 40 years of age, the sight of whose left eye had been destroyed many years before by an injury. A few weeks before my visit, the eye had become much inflamed, and the ordinary remedies were found quite inefficient. When we met, the patient was suffering agonising pain, the lids were much swollen, the eyeball protruded, and there was very severe pan-ophthalmitis. It seemed clear that we must either enucleate, or make a fi'ee incision through the front of the eye. In the hope of at once ridding the patient of all diseased structures, we chose enucleation, and the patient having been chloroformed by my colleague in the case, I then and there performed that operation. In respect to this, it is only needful to mention that a spring speculum could not be used, in consequence of swelling of the lids and protrusion of the globe ; and that the bleeding was, as would be expected, veiy free. The patient was much relieved by the operation, passed a good night, and continued to do well the next day. 770 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA On the second night, he did not get much sleep, but his medical attendant, on visiting him, saw no cause for apprehension. On the fourth day, I was again telegraphed for. Before entering his bedroom we heard liim calling out loudly, and declaring that he was dying ; after a little remonstrance and assurance from us, he became calm and rational. He complained of pain in the top of his head, and said he felt sure that he would not recover. The tongue was clean, the pulse 80, respirations 18 to the minute, the temperature 101-2°. The orbit was healthy, so far as inspection and examination with the finger could show. On enquiry, we were informed that he had some shivering last night. Although strong atropine drops had been put into the right eye previous to my visit, examination with the ophthalmoscope was not easy, owing to the restless state of the patient. I obtained a view of the fundus in the erect image, and found the disc rosy but well defined, and showing the black margin of the choroid at its outer edge. As I was subsequently informed, the symptoms of meningitis became unmistakable, and he died comatose three days after. No post-mortem examination could be obtained. The next case of pan-ophthalmitis, for which I had to operate, occurred in an adult inmate of the Victorian Asylum and School for the Blind. It was severe, though not so bad as the foregoing. I performed evisceration, and the patient did well, but convalescence was much slower than is usual after enucleation. Another patient with pan-ophthalmitis was a youth of seventeen years of age. His case was less acute, and I enucleated with a good result. With present knowledge and experience, I am inclined, in a long standing or very severe case of pan-ophthalmitis, to prefer evisceration, rather than to enucleate the eyeball. Dr. Symgns (South Australia) had hitherto never hesitated to excise a suppurating eyeball. In the future, however, he felt that the propriety of excision in such cases must be considered. Dr. Barrett (Melbourne) related two fatal cases of excision of suppurating globes ; both occurred at Moorfields. In a case in his own practice of perforating wound of the cornea and lens, followed by operation for the removal of the lens, the temperature suddenly rose to 102°; there was severe headache; the symptoms increasing for forty- eight hours, the eye was excised. It was not purulent, simply intensely inflamed. The excision did not relieve symptoms, the temperature continued to rise, the headache increased, and the lids and tissues of the orbit swelled enormously, and for seventy-two hours after excision the condition of the patient was critical. Ultimately, he made a good recovery. Dr. T. K. Hamilton (South Australia) said that, of the two operations before the profession for the treatment of suppurating eyes — enucleation and evisceration — he preferred tlie latter. OCULAR MANIFESTATIONS OF LATE HEREDITARY SYPHILIS. 771 THE OCULAR MANIFESTATIONS OF LATE HEREDITARY SYPHILIS. By G. Adlington Syme, M.S., M.B. Melb., F.R.C.S. Eng. Surgeon to Out-patieuts, Melbourne Hospital. Notwithstanding the many exhaustive researches on tliis subject, one or two questions in connection with it are still unsettled, and it may be of some interest to put on record the following observations: — I find I have notes of 120 cases of various eye affections, mostly keratitis, presumably due to hereditary syphilis; but as some of these are ji little doubtful, I have pruned them down, so to speak, leaving about 100, the specitic origin of which, I think, is unquestionably revealed by other conditions, such as the state of the teeth, the nose and the ears, the history of the period of infancy, or, of most reliance, the history of the rest of the family, and the signs or history of syphilis in the parents. The fact that, in considering the eye affections of hereditary syphilis, one has had to reject about twenty cases of affections, which most "wi'iters consider in themselves absolute evidence of specific taint, must not be taken to imply a doubt as to the correctness of such a view. Notwithstanding the opinion of many French authorities (well expressed by Fournier), that interstitial keratitis is a trophic lesion which may be due to various causes, syphilis being the cause generally, but not exclusively, and notwithstanding the appai'ent reasonableness of this view, I think myself that Hutchinson's opinion, that interstitial keratitis is always due to syphilis, is more correct; it is also more generally accepted. Keratitis need not always be due to an inherited taint, however, and some of the cases referred to have been rejected, because there was a pi'obability that they wei'e due to acquired syphilis. Assuming then, that all these 100 odd cases are due to hereditary syphilis, what tissues of the eye appear to be most affected by this disease 1 Here we at once enter debateable ground. Most authorities say the cornea is the structure by far the most frequently affected, and that interstitial keratitis in par excelleiice the eye lesion of hereditary syphilis. Trousseau maintains that choroiditis is the most frequent condition; but that keratitis always comes under observation, while choroiditis does not. Unfortunately, my cases do not directly help the solution of this question, because, being collected from the oculist's standpoint, almost all the cases came under observation with keratitis; but still they reveal this fact, that choroiditis is generally to be found in an eye affected by hereditary syphilis. Out of the whole 120 cases, in onlyS-l was it possible to carefully examine the fundus, either by examining one eye before the keratitis was present, or by examining after the keratitis had recovered. This examination is always difficult. The cornea is seldom perfectly clear ; oftentimes the pupil is bound down ; and as the choroiditis is almost always situated at the extreme perii)hery, it is easily overlooked. Notwithstanding these difficulties, evidences of choroiditis were found in 47 out of these 54 cases. Out of 102 cases in which the fact was noted, iritis was either present, or had left its traces, in 44. Keratitis, iritis, and choroiditis were all 772 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. three found in only 17. It must be remeuiberecl, however, that most of the cases where choroiditis was found were examined after the keratitis had passed off, and where the iritis, if it had been present, would have passed off also, and especially where the case is early treated, without leaving any traces by which its presence could be detected at this time. The cases where iritis was seen, on the other hand, were in the eai-ly stages, when it was impossible to detect choroiditis. So far as these observations go, therefore, they seem to me to tend to justify the conclusion, that the cornea, iris, and choroid are all affected in the majority of cases (all being undoulited cases of hereditary syphilis). The next question to be settled is — Are these structures affected simultaneously, or if not, in what order are they affected 1 I think the general opinion is that they are all affected simultaneously. Others hold that the cornea is first affected, then the iris, and that from this (especially if neglected) the affection spreads back, causing cyclitis and choroiditis. Another view is that the choroid is first attacked, and the affection spreads forwards some time after the first choroidal changes. This last view may be elaborated as follows : — Syphilis is due to microbes. In hereditary syphilis these are conveyed to the offspring, and excite the so-called secondary phenomena of infancy. Among these, iritis is admittedly not nncommon ; choroiditis also occurs, but is not observed. The tissues gradually get the better of the microbes, and the affection subsides. But the microbes are not utterly destroyed ; they are only held in check, and lie dormant, as it were. Then at a later period, during the second dentition, or in adolescence, when the vital powers are severely taxed, if any depressing cause be added, the microbes over- come the feeble resistance of the tissues, and attack the non-vascular cornea, in which cells quickly accumulate to expel the invading microbes, and new roads, for the access of fresh cells, are formed by its vascularisation. Now this is a very pretty theory, but what facts are there to support it 1 Infantile iritis is not at all common ; on the other hand, as I have shown, iritis very commonly accompanies the keratitis. Again, keratitis may occur, and when it has cleared up, no trace of choroiditis can apparently be found (7 out of 54 cases), and choroiditis almost inevitably does leave some trace in the way of disturbed pigment, or small patches of atrophy ; so that it may be fairly concluded that in some cases, at all events, keratitis occurs without antecedent choroiditis. Then I find I have notes of eleven cases in which one eye only was affected at the time of examination, and in six of these an examination of the choroid of the apparently unaffected eye showed signs of old choroiditis, and in two of these cases the unaffected cornea was watched until it also became affected ; and as interstitial keratitis almost invari- ably does attack l)oth eyes, it may fairly be assumed that the other cornea became affected in the other four cases also. In five cases the choroid was very carefully examined, but no trace of choroiditis could be found — so that we have six cases in which the choroiditis was ante- cedent, as against five in which it was not. Tlie number of cases is too small to form any general opinion as to which event is the more common. We can only say that cither may happen, and that there is no invariable rule. TREATMEKT OF INHERITED SPECIFIC KERATITIS. < / .) Tlien I tried to find out, l)y direct examination of tlie fundus of infants with hereditary syi^hilis, whether the choroid was affected at tliat period, but I had very few opportunities, and when tliey occurred the motliers objected to the prolonged examination and to atropine, and tlie infants were so restless, that I found it impossible to be absolutely sure that there was no choroiditis, and I gave up the attempt. I did tind it in one case, however, at 10 months old, but it was associated with neuro-retinitis and optic atrophy. I have also notes of one case, who appeared at ^loorfields, with interstitial keratitis at 19, and who brought an old card which showed that, at the age of 11, he had attended with choroiditis. He also had high myopia, but his sister had keratitis, and the history of the family and other collateral evidence showed the specific nature of the case very clearly. Thus we may fairly conclude, that in some cases, at all events, the choroiditis does precede the keratitis, but in what proportion of cases this happens is undetermined. It also appears that keratitis may occur alone, but I think in by far the majority of cases keratitis, iritis, and choroiditis occur pretty much about the same time. The age at which the choroiditis occurs is obviously difficult to determine, because its onset causes little or no disturbance in most cases, and it is only found long afterwards. It may be remarked, that Trousseau considers that it occurs at a comparatively late period — 9 to 12, or 20 to 25. Out of the forty-iive cases in which I found it present, it was discovered before the age of 12 in twenty-one cases ; and of these, ten were discovered under 9. There is only one other point to which I wish to refer. It is generally admitted that choroiditis may occur apart from syphilis ; and Hutchinson, after many years' research, concludes that in a few cases it may so occur, and that when it does, the final results are indis- tinguishable from those of syphilitic choroiditis. As far as my observations go, they are fully in accord with this opinion ; but some confirmation of a supposed syphilitic origin has been found in unexpected ways, when the direct evidence seemed very slight indeed, and the extreme difficulty of eliminating the possibility of a syphilitic origin has im- pressed itself upon me most strongly. ON THE TREATMENT OF INHERITED SPECIFIC KERATITIS. By James Jackson, M.D. Lond., M.R.C.S. Eng. Cases of inherited specific keratitis are so frequently met with in the practice of those specially engaged in ophthalmic work, and even in general medical ])ractice; and, moreover, many of these are so severe, and result in such disastrous consequences to the eyes, that any deviation from the usual mode of treatment which tends to mitigate the severity of the symptoms, or shorten the duration of the disease, and wjiich leaves the cornea free from opacities when the disease has run its 774 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. course, is worthy of record. Observations extending over many years^ and enquiries made of patients who have suffered severely from this- affection, and wliose corneie have become more or less spoiled for visual purposes by dense opacities or lenconiata, have led me to believe that specific remedies have either not been employed at all, or only to an extent altogether inadequate to influence favourably the course of the disease. My usual practice in the treatment of such cases, for a long time- past, and that which I desire to bring before the notice of members, has been to use vigorous mercurial treatment from the very onset of the attack, and to keep up the influence of the drug uninterruptedly (short of producing ptyalism) for a period of six weeks or two months, to V)e followed by ferruginous tonics, and alternating this for some time after with the specific at first used. At the same time, every attention must be paid to the state of the general health, by insisting upon a liberal dietary, and as much open air and exercise as the state of the patient will admit of. Where treatment such as I have indicated is employed, a mai-ked improvement soon manifests itself; and I have noticed that the second eye (which in the ordinary course of events suffers in a similar manner) either escapes altogether, or if attacked^ that the symptoms are much milder than would otherwise have been the- case. I am aware that many leading authorities wlio have written on this- subject have expressed themselves as averse to the use of mercurials, preferring a tonic plan of treatment from the commencement, or employ- ing only the iodide of potassium ; with this, however, I cannot agree, and my experience leads me to regard the prompt use of mercury as of the greatest importance in mitigating the severity of the symptoms, ancE inducing a more rapid convalescence, at the same time that the cornea is left more free from opacities and faulty curvature, and the eye there- fore more useful as an organ of vision. The form of mercurial used may not be of importance, but that which I usually employ is a combination of the liquor hydrarg. perchlor. with the potassium iodide in full doses, at the same time rubbing in the ung. hyd. co. to the temples, and instilling atropine for the purpose of preventing synechiee, or in the event of these having already formed (which is too often the case),, breaking them by strong preparations of atroi)ine (8 grains ad. ^j). Case T. Miss 8., aged 7 years, was brought to see me on August 29, 18S7,. and four months after the eyes were affected. The pain and photophobia were so severe, that a satisfactory inspection of the eyes could only be made under the influence of an anaesthetic, when V)oth cornete were found covered with dense ojiacities, which rendered an examination of the deeper structures impossiljle. No history of her previous treatment could l^e ol)tained, so that I am unable to say whether specific medicines. Lad been used. The licjuor hydrarg. ]»erchlor. and potassium iodide in full doses were given, the ung. hyd. co. was rubbed into each temple, and atroi)ine drojis were instilled three times daily. At the end of two months a decided im])rovement had taken place, the pain and photo- phobia were much less marked, and a steady convalescence ensued. The girl is now fairly well in her general health, but the opacities of the TRKATMENT OF INHERITED SPECIFIC KERATITIS. 775 cornea are so dense, and the astigmatism resulting from the faulty curvature of the cornea is so gx'eat, tliat for visual purposes the eyes are seriously impaired. Case II. Maude T., aged 14, came under treatment in May 1884. The left eye, which from infancy showed considerable divergence and was more or less amblyopic, was attacked with kerato-iritis fourteen days before. Three weeks after this the right eye became affected in a similar manner, and corneal haze, with marked impairment of vision, was manifest for the succeeding two months, when, after employing the usual vigorous mercurial treatment, im])rovement set in, and satisfactory convalescence ensued. The vision of the right eye had so far recovered at the end of the following September (six months from the date of attack), as to enable her to resume her school duties. The upper incisors showed decided evidences of the specific taint, but were Vjy no means typically malformed. Any doubt, however, as to diagnosis, was removed by the fact that a clear history of specific infection was elicited from the mother, and that a brother, whose incisors showed characteristic lesions, subsequently suffered from kerato- ivitis. At this date (four years after the attack), vision Oc. Dex — f and Xo. 1 Jager, with the cornea apparently quite free from opacities, and this, notwithstanding that one year ago the eye became attacked with glaucoma of a very acute form, for the relief of which an iridectomy was performed. Case III. Ernest T., a brother of the patient above referred to (and wdiose case has already been incidentally mentioned as presenting the characteristic dental lesions), was brought to me in May 1887 with kerato-iritis of the left eye. The usual specific treatment was employed, when steady improvement soon set in, leaving the cornea perfectly clear, and without any trace of opacity — V = -^-g, and No. 1 Jjiger. On further examination, the defective vision for distant objects above noted was found to be due to a previously existent astigmatism. The other eye escaped altogether, and up to this date remains well. In both the latter cases, the general health underwent a marked improvement. Case IV. Miss S., set. 19, of Kyneton, was sent down to see me by her medical attendant on August 29 of this year. This young lady, a person of strumous habit, and markedly anaemic ajjpearance, was sufiering from acute kerato-iritis of the right eye, the affection having already existed for one month. The pain and jihotophobia were extremely severe, making a satisfactory inspection of the cornea a matter of some difficulty. Tiie cornea was found to be densely covered with haze of the usual ground-glass character, the ciliai'y zone of vessels was well marked, and after the a])plication of a strong preparation of atropine witli vaseline (grs. viii. ad. J j), no mydriatic effect was in the least degree perceptible, posterior synecliije being nearly complete. The lids and soft jiarts surrounding the eyes were in a state of acute oedema, accompanied \)y more or less chemosis. There was not much difficulty in making a 776 INTERCOLONIAL MEDICAL CONGllESS OF AUSTRALASIA. diagnosis, the local lesions of themselves sufficing to establish this, but an inspection of the teeth removed any doubt that may have existed, the upper incisors exhibiting in a marked degree those peculiarities of form, &c., so frequently met with in cases of this kind. Specific medicines in fiill doses were administered, the ung. hyd. co. rubbed into the temples; night and morning, and a strong pre})aration of atropine and vaseline (grs. viii. ad J j) was persistently used to break down adhesions to the capsule, a matter of considerable difficulty. For six weeks this treat- ment was persevered with, at the end of which time a marked improvement had taken place, the pain and photophobia had disappeared, and the iris was found to be nearly free from adhesions, one or two tags of synechipe alone remaining. About this time the left eye became affected, but the attack was altogether of a much milder character, and at the end of a fortnight, the more acute symptoms had almost entirely disappeared, leaving the cornea clear and the iris altogether free from adhesions — V 12 and L — |^ and No. 1 Jjiger. ■Case V. Miss K., pet. 15, was placed under my care on September 28, 1888. Four weeks had elapsed since the right eye was attacked. The cornea was covered with a dense haze, which limited vision to mere p. 1. The sclerotic zone of vessels was well marked, and pain and photophobia were complained of. Although in this case an examination of the incisors threw no light on the nature of the case, the earthy physiognomy, cicatrices at the angles of the mouth, and a history of infection in one of the parents, ]ilaced the diagnosis beyond a doubt. After the iisual specific treatment was adopted, a rapid improvement in the general health took place, and the corneal haze is now represented by one opaque dot, scarcely exceed- ing a pin's head, which occupies the centre of the cornea. So far, the other eye has remained free from attack. Case VI. N. M., set. 26, consulted me on July 26, 1888. The right eye, which had already been affected for three weeks, showed dense corneal haze, with a well-marked sclerotic zone of vessels. There was also a moderate amount of photoijhobia, with slight pain. After vigorous specific treat- ment had been persisted in for six weeks, the cornea was left faintly covered with haze, which, under the influence of massage with ung. hyd. flava, is rapidly disa])pearing. Uj) to this date, the left eye has remained free from attack. In this case, the dental lesion is characteristic. [Dr. Jackson exhibited the cases referred to.] Dr. SvMONS (South Australia) said two ])oints arose in his mind : the possible toxic effects of strong solutions of atropine — he had never used anything stronger than six grains to the ounce ; also, what is the maximum age at which interstitial keratitis can occur? The oldest patient he had ever seen suft'ering from it was aged 42. Dr. Duncan (Kyneton) spoke relative to the question of the possible toxic effects of using atropine in strong solution. He used it eight grains to the ounce ; he had seen atropine irritation, and .sometimes OPERATIXG ON EYES IN CASKS IN WHICH MUCOCELES CO-EXIST. 777 ilryness of tlie tliroat, result, but never anything more. Witli respect to the causation of interstitial keratitis, he should regard all cases as specific in so far as treatment was concerned. Mr. Syme (Melbourne) said the effect of mercury in the treatment of interstitial keratitis is marked. Tlie disease can occur to an advanced age. Half the cases ai-e over fifteen years ; the oldest ])atient he had seen was aged 32. It was necessary to i-emember that, in cases of an advanced age, there is always a possibility of tlie keratitis V>eing due to aO(iuired, and not. to hereditary, syjihilis. The idiosyncrasy patients exhibit to atrojnne is remarkable. In the later stages, when the redness has disa]>peared, yellow ointment and massage are valuable auxiliaries. Atropine should be used as a routine i-emedy in this disease. Dr. Barrett (Melbourne) was in the habit of using atropine oint- ment, eight grains to the ounce. He considered the action more powerful and more safe than that of atropine used in sohition. He quite agi'eed with Mr. Syme, that atropine should be used as a matter of routine in all cases of interstitial keratitis. Dr. Jackson replied to the effect that he quite agreed with Dr. Barrett as to the relative danger of using atro])ine ointment and atropine solution. Toxic effects might result (when the solution is used), from the solution finding its way into the canaliculi and nasal duct. THE DANGER OF OPERATING ON EYES IN CASES IN WHICH MUCOCELES CO-EXIST. By James W. Barrett, M.D., M.S., F.R.C.S. Eng. At-sistaut Siirgeon to the Victorian Eye and Ear Hospital, and Demonstrator and Examiner in Physiology in the University of Melbourne. I believe most ophthalmologists are aware of the dangei- of extracting cataract in cases in which the eye is the subject of chronic conjunctival affections, and of mucocele. The fact that a slight afi'ection of this nature may be quite sufficient to ruin an operation was insisted on by Streatfield. It would seem that in such cases, it is quite impossible sometimes to render the conjunctival sac aseptic ; and consequently, when the eye is bandaged up, micro-organisms, kept warm and moist, multiply, and ultimately enter some ])art of the large cataract section, causing either local sloughing, or if they j)enetrate far enough, |ianophlhalmitis. Yet, apart from the cataract operation, I was not aware that there was great risk in operating on such eyes. It is a matter of every day experience to see performed iridectomies in cases of trachoma, and in cases of rodent ulcers of the cornea. Personally, I have made more than one puncture in the anterior chamber quite thi-ee millimeties long, in cases of gonorrhoeal oi)hthahnia, and with good results. In these cases, however, the eyes were not tied up after operation. Still, I had rarely 778 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. seen unfavourable results follow iridectomies in such cases as T have referred to, and I was quite unprepared for the following disastrous case which, as far as I know, is without parallel: — Mary W., set. 60, was admitted into the Eye and Ear Hospital in September last, under the care of Dr. Bowen. In his absence from Melbourne I had charge of his patients. She was suffering from double mature catai'act, for which I determined to perform preliminary iridec- tomies. On September IS, 1888, I performed a large upper iridectomy on the right eye, previously anajsthetising it with the usual aseptic solution of cocaine and boracicacid. The eye was bandaged up for forty-eight hours in the usual way, and at the end of that time the wound had healed; the eye was quiet, and showed little reaction. On September 22, I was about to perform a similar operation on the left eye — which had been anaesthetised with a cocaine and boracic acid solution, freshly made up — when I noticed on the lower lid a small quantity of gelatinous mucocele fluid. I squeezed the sac, and got away a little more fluid. I then examined the other eye, and found it in exactly the same condition. The conjunctiva of the left eye was white, and the mucocele was so slight that, as stated, it had been quite overlooked. I carefully cleaned the left eye, and then washed the conjunctival sac with a solution of bichloride of mercuiy — 1 in 5000. An u])per iridectomy was then performed, through a comparatively small incision, and without the least trouble. The eye was bandaged up, and the patient put to bed. In both cases, the knife used was the triangular sclerotome. The same instruments were used by me a few minutes later for the perform- ance of another iridectomy for closed pupil — a case which did well. Twenty-four hours after the operation, the patient complained of severe pain. The bandage was removed, when yellow lymph was seen in the pupillary area. An attack of panophthalmitis had set in, and ulti- mately the eye was desti'oyed. The iridectomy on the other eye remained a success. Here, obviously, the disastrous result was due to the infection of the eye through the small puncture made with the sclerotome. I do not think it at all possible that the infection was made by the instruments, which were kept cleaned, and dipped in absolute alcohol prior to use. In fact, the successful result of the iridectomy performed with the same instruments, with the use of the same cocoaine solution, a few minutes later, tends to confirm this view. The infection was almost certainly due to the septic character of the lachrymal sac and conjunctiva. I do not think further comment is necessary, but I thought I could not do better than place such a case on record. If I am compelled to operate on such an eye again, I shall slit up the canaliculi, and thoroughly wash the sacs for some time prior to operation. I may add that in this case, subsequent to the attack of panojih- thalmitis, the canaliculi were slit up, and little or no fluid was evacuated, so slight were the mucoceles. Dr. Jackson (Melbourne) said that he had performed the cataract operation on the eye of a patient who suffered from ciironic ophthalmia. Suppuration set in two days afterwards, as a direct lesult of septic OCULAR SYMPTOMS DUE TO DISEASES OF THE NASAL CAVITIES. 779^ infection of tlie wound, and the eye was lost. He should hesitate in the future to operate in such cases. Dr. DuxcAK (Kyneton) said that ho could not understand the manner in which a mucocele could infect the wound. He had performed a preliminary iridectomy in a cataract case in which there was no mucocele, and no suspicion of septic infection; yet panoi)hthalmitis had set in, and he had been compelled to excise the eye. Dr. M. J. RvAX (Kyneton) had seen Dr. Duncan's case. Mr. J. T. RuDALL (]\Ielbourne) said that a few years ago we were taught that the entrance of microbes alone could cause suppuration. He now noticed that the subject was opened up again, and that experi- ments had been performed, which seemed to show that such irritants as mercury and turpentine, introduced under the skin, could cause suppuration in the absence of microbes. OCULAR SYMPTOMS DUE TO DISEASES OF THE NASAL CAVITIES. By T. K. Hamilton, M.D., F.R.C.S.I., Laura, South Australia. The sul))ect I have chosen to bring before the Section is one, I think, of great interest, and of considerable jn-actical importance to the ophthalmologist. I am not sure that there has been anything written up to the present on this subject in our Australasian colonies, nor can I find much reference to it amongst the writings of specialists in Great Britain. It is from America and the continent of Europe most of our information comes. Of the continental writers, I would refer particularly to Bresgen (" Der Chronische, Nasen- und Rachen-Catarrh," 1881, Band 1, and " Grundziige einer Pathologic und Therapie des ISTasen-, Mundrachen- und Kehlkopf-Krankheiten," 1884), who was the first to draw the attention of specialists to the fact, that conjunctival catarrh is lai-gely dependent upon so-called nasal catarrh, and that it will not disappear until the latter be relieved ; Ziem, Dantzig [Centralblatt f. Frak. Augen- heilkunde, December 1887) ; ISTieden, Bochum (Arch. OphthaL, December 1887 [translation] ) ; and Peltesohn, Berlin [Centralblattf. Prak. Aiigen- heUkunde, February 1888). And of the American — Gruening, New York (New York Medical Record, January 1886) ; Gradle, Chicago [Chicago 2[edical Jounud and Examiner, March 1887, and Arch. Ophthah, December 1887) ; Cheatham (America)/, Practitioner and, Neios, 1887), and Bettmann (Journal American Mediccd Association, May 1887, and Revue des Sciences Mtdicales, Fasc. I., 1888). I have endeavoured to work out the subject as thoroughly as possible, 80 far as the time during which I have been making my observations would allow, and I hope to be able to establish to your satisfaction a very distinct and close connection between the eye and the nasal cavities, as evidenced by symptoms and reflex phenomena discoverable in the former and co-existent with diseases in the latter. 7S0 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA, In the first place, by way of preface, allow me to point out briefly the relation these cavities (nasal) stand in to the eyes anatomically. In addition to the direct continuation of the epithelium of the nose with that of the eye, there are distinct vascular and nervous connections. (1) Arterial. — The ophthalmic artery supplies the anterior and posterior ethmoidal, which, passing through the cribriform plate of the ethmoid, reach the nose and go to nourish the anterior part of the septum and the lateral portions of the nasal cavities, anastomosing with the nasal or spheno-palatine of the internal maxillary. In addition to this, Zuckerkandl has shown that there is a direct arterial communica- tion passing along the naso-lachrymal canal. The naso-pharynx has likewise some arterial supply from the internal maxillary, and is thus indirectly introduced into the nasal vascular circuit just referred to. (2) Venous. — The veins of the nose anastomose extensively with the ophthalmic vein through the plexus lachrymalis, and some find their way into the cavernous sinus. (3) Nervous. — The nasal of the ophthalmic supplies, through its internal and external branches, the upper and anterior part of the septum, and the outer wall of the nasal fosste, which nerve at the same time, through its long ciliary and infra-trochlear branches, goes to form part of the ciliary ganglion, and to supply various parts of the eye ; and again, through this same ganglion, to give branches to the ciliary body, cornea, and iris. Once more we have the spheno-palatine going to form Meckel's ganglion, which in turn, through its anterior superior naso- palatine and vidian branches, supplies the nose; and through its external posterior and pharyngeal, with the vidian again, the upper part of the pharynx. The following is an abstract of the cases : — Case 1. — Empyema of the antrum and unilateral hypertrophic rhinitis of the left side, attended with eye symptoms : — (1) Concentric contraction of the visual fields for all colours. (2) Accommodative asthenopia. (3) Retinal hyperissthesia. (4) Peciiliar subjective sensations of light. ' (5) Photophobia, with blepharo-spasm and infra- orbital neuralgia. The evacuation of the empyema and its cure were speedily followed by the disa])])earance of the eye symptoms. Case 2. — Ecchondrosis of the triangular cartilage and chionic rhinitis. This case was attended with the following eye symptoms : — (1) Asthen- opia. (2) Pain in the eyeball. (3) Injection of the eyes when used for close work. (4) Blepharo-spasm. (.5) Contraction of the visual fields. These symptoms disappeared on the removal of the growth. Case 3. — Spine of the bony septum, causing chorea magna. The following eye symptoms were present :- — (1) Asthenopia. (2) Sub- jective colour sensation. (3) Sneezing. (4) Contraction of the fields of vision. These symptoms disapjieared on the removal of the spine. Case 4. — Advanced chronic atrophic rhinitis, with middle turbinate hyperplasia. The following eye symptoms were present : — (1) Asthen- opia. (2) Lachrymation. (3) Puffiness of the lower lid. (4) Con- traction of the visual fields. These symptoms were relieved by the treatment of the nasal condition. CASE OP DOUBLE GLAUCOMA FULMINANS. 781 Case 5. — Syi)hilitic oztena. The following eye symptoms were present: — (1) Asthenopia. (2) Lacliiymation. (3) Pericorneal injec- tion on using the eyes. (4) Contraction of the fields of vision, which was temporarily removed by the use of amyl nitrite. These eye symptoms ameliorated as the nose improved. Case G. — Polypi, nasal and naso-pharyngeal, with eye symptoms similar to those recorded. Cases of Post-xasal Growths. — In lOG cases, eye diseases co-existed in 51; in 22, catarrhal conjunctivitis; in 7, follicular conjunctivitis; in 16, granular conjunctivitis, and in 6, blepharitis (marginal). One typical case of post-nasal growth, with reflex eye sym|)toms, is recorded. There was asthenopia and limitation of the field. The growth was removed, and the eye sym]jtoms disappeared. A CASE OF DOUBLE GLAUCOMA FULMINANS. By GuiDO Thox, M.D. Mrs. T., set. 45, married, six children, was seized with violent pain in the right eye on the early morning of the 4th of April last, attended with vomiting, and followed in a few hours by loss of vision. On the early morning of the 23rd of April, similar symptoms appeared in connection with the left eye. In both cases there was some conjunctival injection. On April 2Sth, she was seen by the writer, who found the eyes small and receding. The blindness was absolute, the patieiit being unable to distinguish night from day. Appearances : — Bight eye T -f- ; some conjunctival injection ; cornea a little cloudy ; pupil seven to eight millimetres in diameter, immovable • anterior chamber shallow ; fundus reflex, faint. Left : — Conditions similar, but not so marked. On April 30th — twenty-five days after the attack in the right, nine days after the attack in the left — a doAvnward iridectom}^ was performed on the right eye ; the iris was rotten ; the lens was touched with the knife during the operation, on account of a sudden rush forward. Tlie iridectomy in the left eye was successful. Ultimately the wound in the right eye healed, but the eye remained irritable and was ultimately excised. The left eye did well, and vision was recovered to the extent of distinguishing shadowy outlines of lar^'e objects, although there was an opacitj' on the anterior surface of the lens. 782 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. POST-NASAL GROWTHS. By T. K. Hamilton, M.D., F.R.C.S.I., Laura, South Australia. During the past twelve months, I have examined in detail the upper respiratory tracts (and in many cases the larynx also) of about 260 individuals, between the ages of two and a half and twenty-five years, with a view of forming some idea of the relative frequency of post-nasal growths and enlargement of the pharyngeal tonsil in the colony of South Australia. Out of this number, eighty-four had post-nasal growths, and thirty-two enlargement of the pharyngeal tonsil. You will notice I make a distinction between post-nosal growths and enlargement of the pharyngeal tonsil. I do this more to emphasise the fact that, in the former, the growths were large, irregular, and distinct ; while in the latter they were regular, lobular, and more joined together — in fact, only a hypertrophy of the normal lymphoid structure of the naso-pharyngeal vault. There is really no physical difference between the two affections ; it is merely one of degree. About the actual locality from which these growths spring, there is some difference of opinion amongst authorities. Trautmann, for example, maintains that they grow only from the roof of the cavity, and never from the sides ; and he says he has verified this statement by post-mortem examinations. He admits, however, they very frequently seem, in the rhinoscopic image, to spring from other places than the roof, but this, he says, is an optical delusion. Now, as far as I can make out, the anatomical position of the pharyngeal tonsil itself is opposed to this view ; for this body, in the normal condition, occupies not only the roof and upper part of the })osterior wall of the naso-pharynx, but also extends laterally into Rosen- miiller's fosste, and even on to the Eustachian cushions. If this be so, and if post-nasal growths are only, as stated above, an excessive development of this tonsil, we are not surprised to find the majority of authorities taking exception to this, the view advanced by Trautmann. Molden- hauer says : — " From my own numerous observations on the living subject, I find that this assertion of Trautmann's requires further confirmation. It has not infrequently hapjiened to me," he continues, "that after the removal of the growths from the roof and the posterior wall, still swellings remain which seem to spring from the fossiB of Rosenmiiller, and the mouths of the tubes are more or less covered." Schech sui)ports this view also ; but the most recent authority on the subject is Rostanecki, who, after reviewing the existing literature, and comparing it carefully with his own thorough investigations, comes to the conclusion that the pharyngeal tonsil may extend to the tuberosity of the tubes, and even into the ostium, and that those modern authors who state otherwise are wrong. I have referred thus fully to this, because the question of exact locality has a practical importance, as we shall see presently, when we come to deal with the removal of the growths. I myself have, in several of my cases, been able to observe the growth proceeding from the lateral aspects of the cavity, and by digital examination to make myself absolutely certain of the fact. POST-XASAL GROWTHS. 783 Next, as to the etiology of the growths. This I think, especially to us in these Colonies, is a most interesting question, and one on which I trust my remarks may elicit some discussion, as I am anxious to arrive at correct conclusions. Some eminent authorities, such as Bresgen, Lange, and 8emon, believe they are congenital, and that they are not observed until several years after bii'th, on account of their slow development ; but Schech points out, that the predisposition of children to the artection is not remarkable, since otiier organs, sucli as the tonsils, are in childhood very often affected with hyperplasia. No dissections, however, of new-born infants have confirmed this congenital theory. According to Trautmann, ten months is the youngest age at which tliey have been found to exist. The difficulty experienced in examining tlie naso-pharynx in very young children will, I believe, always prove an obstacle in the way of getting statistics from the living subject. An attempt made by me recently to examine an infant of eight months, only convinced one how difficult, indeed how impossible, it is to get the index finger round the soft palate into the small cavity above. One feels as if the pressure necessary to get round the corner would, if persisted in, disturb some of the bony relations, and you feel irresistibly inclined to desist. The next question to decide is — Are these growths a " scrofulous ' lenorrhoea, nor even a hypertrophic rhinitis, for in most of my cases I find, if they be at all chronic, more atrophy than anything else. A very common condition is atrophy of the inferior and hypertrophy of the middle spongy bones ; or again, atrophy in one nostril, and hyper- POST-NASAL GROWTHS. 785 tro])liy or a normal condition in the other. Out of thirty-five of my cases in which the condition of the nostrils is recorded, I find atrophy more or less present in twenty-six, and hypertro})hy only in seven. What is the origin of this chronic nasal catarrh 1 Is there any catarrh children are so liable to as nasal 1 I think not. "We frequently see catarrhs originate in an attack of one of the exanthemata, and become chronic afterwards. This may, in children of lymphatic tendencies, be the starting-point of any lymphoid enlargemenl ; but this catarrh much more frequently conies on idiopathically, as secondary to derangement of the general alimentary system. This derangement has its origin somewhere in the digestive tract, and secondarily affects other parts of the body. Let us see how it comes about. The excessive consumption of animal food in these colonies is notorious. Even young children are allowed to eat meat at all three meals, and that daily. This nitrogenous food is taken to the exclusion of starchy and other foods more suitable for youthful digestion and assimilation. Along with this they are given, also at all three meals, tea to drink in quantities. Tea is said to delay the digestion of the proteids, and the quantity imbibed must necessarily dilute the gastric juice and prevent its action on the food until the excess of water is absorbed. Again, the large consumption of sugar and saccharine materials amongst children is injurious. Sugar is known to be eminently catarrhal, and is now, by most authorities, recommended to be excluded from the diet of those who have such tendenc3^ My own observation has abundantly proved that an abstinence from all kinds of sugar has made those who suffer from the various catarrhal conditions of the throat and nose (many of which are only secondary to gastric or intestinal catarrh) much less suscei)tible. There are, of course, other contributory causes — e.r/., rapid or sudden changes of temperature, so common in certain seasons in our climate ; neglect of cleanliness or attention to one of the most im})ortant excretory oi'gans of the body — the skin ; but I cannot do more than mention these here. The analogy which has been proved to exist between the pharyngeal and faucial tonsils at once explains how it is that we nearly always find hypertrophy of the two co-existing in the same individual. Out of 116 cases of post-nasal growths, ninety had enlarged tonsils; and out of the 260 throats examined, 132 had this complication; and, further, out of this last-mentioned number, there were thirty-nine cases in whicli the left tonsil was larger than the right. This may be of some interest to notice in passing, as we know that in the case of at least one other of the double organs of the body, this also occurs. I refer to the testes. Once more, the rough condition of the posterior pharyngeal wall, which invariably accompanies post-nasal growths, is only a similar lymphoid hypertrophy; and hence, having the same histological and pathological origin, we w'ould expect to find them, as we do, so constantly co-existing, that the presence of the one on the lower pharynx almost certainly implies the presence of the other higher up. To recapitulate briefly, this then is my contention. Scrofula, or some such diathetic tendency may, in many cases, exist as a strong predis- posing cause to lymphoid hypertrojohy in the pharynx and naso-pharynx ; but there are exciting causes whicii, in these dry climates, unfa\ourable 2e 786 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. to scrofulous developments, determine the existence of post-nasal, pliaryngeal, and faucial growths much more surely than diathesis alone ; and these causes are principally connected with digestive derangement induced by an unsuitable dietary, and one in keeping with neither the climate nor the digestive or assimilative powers of the individuals. I cannot do bettei*, in concluding this interesting part of the subject, than quote the remarks recently made by Beverley Robinson (New York). He says : — " Catarrhal troubles are sensitive to reflex influences, wherevei' other organs are affected to any extent, and wherever the nutrition and general tone of the system is interfered with. Next to local causes it is a frequent source of the origin and aggravation of catarrhal trouble. Chronic indigestion presents many examples of this, both through reflex influences, or by its disasti'ous effects on the bodily nutrition — some cases in which the condition of the alimentary canal was proved to be alone responsible for the origin of the catarrhal trouble." Signs and Symptoms. (Jf the signs and symptoms connected with post-nasal growths, I will only refer to some of the rarer ones, the others being too well known to re])eat : — (1) Noise and Difficulty in Siuallotving. — I had two illustrations of this. The patient, as it were, made a double effort to swallow, sometimes at the same time making a noise extremely disagreeable to those, joining in the meal. (2) Larpigismus Stridulus. — Of this I had four instances, and as far as I can tell, the removal of the growths has caused these attacks to cease. Hering (of Warsaw) refers to this as a symptom of nasal disease {sjaasme larynge). (3) Couyh (Useless), and Hawldng. — This is fairly constant as a symptom, and, in the absence of other disease, should lead you to examine the naso-pharynx before you do, what I think is nowadays too often done, place the case in the category of the "neurotic." (4) Asthenopia. — Referred to in my paper, " Ocular symptoms due to disease in the nasal cavities." (5) Epistaxis. — One does not wonder at this occurring, as the growths are themselves so vascular, having a special arterial and venous supply for each growth separately. (6) Defective Nutrition. — This is extreme in some cases. One child, from whom I removed both post-nasal growths and enlarged tonsils, only wciglied thirty-six pounds. She was 7 years old, and in ten days after the operation she had gained two pounds. It is marvellous how children begin to pick up after the removal of growths, when the growths have been, as they always do in cases where there are large numbers, interfering seriously with their nutrition and development. (7) Deafness. — This is one of the connnonest and most important of all the concomitants of post-nasal growths. Out of my 116 cases, forty complained of deafness more or less, some very extreme, and in eight of these cases there was jierforation of the membrane and otorrhoea. Tlie intimate relation of post-nasal growths to middle ear disease is of great im])0rtance, as shown by Meyer's statistics ; he has found middle POS'l'-NASAL GKOWTIIS. 787 ear disease in 70 ])t'r ce)it. of liis cases of [tost-nasal growtlis ; und Gradle has found tliat, in more tlian one-tifth of the children brought to him for ear disease, there is hyjiertrophy of the phar^'ngeal tonsil. These statistics show how important it is, that in all children who snti'er from recurrent or chronic middle ear disease the naso-pharynx should be carefully examined, and growths removed when they exist. Greville Macdonald lays it down as a rule, that where deafness exists the growths should always be removed, even though they be compara- tively few in number and small. I removed a moderate number of growths in a case like this from the nHso-pharyn.\ of a weakly lad, aged 12 years, who had constantly recurring though slight sujipurative catai'rh. The result has been most satisfactoiy. He has not had any return of discharge since their removal. The following two cases are typical, showing the very distinct connection existing between the growths and the otorrh(]ea : — In case No. I. — The otorrhoea had been of long standing (two and a half years), in ten days it is cured, and has never returned since. In case No. II. — Double oton-luea of four years' standing, following scarlatina; eleven days of treatment, after the removal of the growths, sutficed to sto]) the discharge, which has never returned. Methods of Examining. A very few words as to tlie methods of examining for post-nasal growths. Killian (Hartmann's " Klinik," Berlin) points out the great advantage of anterior rhinoscopy in the diagnosis of growths, but says you must use cocaine to i-educe the inferior turbinates, in order to get a good view. The Germans all lay stress u))on this mode of examination, but I frankly admit I seldom or never resort to it, as I have always found so little good resulting from the examination. You may see parts of the growths if they be isolated, but as to coming to any conclusion as to their number, position. or size, I never could, hence either posterior rhinoscopy or the digital examination are what I always practise. Posterior rhinoscopy gives, as a rule, uncertain information ; it is very satisfactoiy, in one sense, to see the objects you are going to remove, but on account of the great perspective shortening with which the parts under examination are represented, the lowest tumours only can be observed, while those lying above are either quite concealed, or appear much smaller ; hence the digital examination is much the most satisfactory and reliable. The correct method of pro- cedure ])robably is tliis : — See what you can through the anterior nares, then examine by posterior rhinoscopy. If you can get any image at all, you can usually satisfy yourself from the apjjearances, taken along with the symptoms of the case, whether it be one for o})eration or not. You may then reserve your digital examination until you are operating, when you can by a few sweeps of the linger dete^uaine accurately the condition of the growths, before applying the instrument you are about to use for their removal; this saves the patient the unpleasantness of on(! examination with the finger, which is desirable. If, on the other hand, you fail to get a post-nasal image, as you so often do in children, there is nothing for it but a digital examination there and then, and of all examinations it is the best. I find I can often, by a little delicate manipulation of Michel's rhinoscopic mirror, avoiding carefully any contact with the posterior pharyngeal wall, at the same time pressing the 2e 2 788 IXTERCOLONIAL MEDICAL CONGKKSS OF AUSTUALASIA. back of the tongue well down with a Frankel's tongue depressor, get an image impossible to obtain by the ordinary mirror. The paretic condition of the velum, and the semi-anfesthetic condition of the posterior wall, facilitate posterior rhinoscopic examination in many cases very considerably. Lastly, as to the Methods of Removal of the Growths. Out of the 116 cases (referred to already), I have operated on sixty-six. One has to consider the age at which it is desirable to operate ; about this there is no rule. I have operated on two children at the age of 4 years, but there is some difficulty in children under 5 years frequently. The cavity is so small, that it is not an easy matter to get yoiu- finger and an instrument into it at the same time. If symptoms exist which require the removal of the growths, I think the sooner they are removed the better. Stoker (London) points out that physiological idleness means arrest of development, and the sooner the obstruction is removed, the less the deformity ; so the circumstances of each case will form the 1»est guide as to when you should operate. I have given up using any general antesthetic, as I think it is quite unnecessary. Some recommend chloroform, pushed to cause complete anaesthesia, and others use ether for similar purposes. As I have just said, I think any anaesthetic unnecessary, and perhaps j)Ositively injurious if complete anaesthesia be caused, for then you arrest reflex action, which it is particularly valuable to retain, in order that the patient may be able to cough up any blood which may And its way into the larynx, as it often does, no matter what position the head is |)laced in. I sometimes apply 10 per cent, solution of cocaine to the interior of the nose (especially when about to use Meyer's ring knife), to the naso- pharynx, into which cavity I inject a few drops (patient lying down, with head low) with a small post-nasal syringe (made for the purpose by Windier, Berlin) through the nostril ; and finally to the posterior wall, etc., with cotton on a cotton-holder. In addition to this, I generally now give the patient a large dose (gr. xxx to xl) of Ijromide of potassium, half an hour })revious to the operation ; latterly, I have given or applied nothing but this, and it makes the greatest possible difference in the tractability of the patients, both young and old. McKeown it was who recommended this in small operations on the eye, e.g., tenotomy in strabismus, etc., and I find it particularly suitable for nasal and post- nasal operations. The position of the patient. — He is made to lie on a low couch, with tlie head hanging over the end, and lower than the rest of the body, so that the blood will flow back out of the nostrils, and not downwards into the larynx ; though it is often impossible, even in this position, to avoid the latter entirely. This position is by far the best, more especially for the removal with any of the forceps instruments, but the couch should be low, so that the operator is well above his patient. This is also a most convenient position for the removal of tonsils, especially in young children. If the tonsils are enlarged, I remove them first ; this clears the way for gaining access to the naso-phaiynx, and when the hemorrhage is ceased, I attack the growths. Of the many instruments in use for removing post-nasal growths, I find none so universally suitable as Woakes' modification of Liiwenburg's AURAL DISKASE AND EPILEPSY. 789 forceps. I generally use it, unless I find that the shape and position of the growths are sucli that they can be readily included in the cutting range of a Gottstein's knife. This instrument is used a good deal in Germany, and the patient operated on in the erect })osture with it. Tlie good rule laid down by Meyer is likewise now adhered to ; his rule is — "no instrumental removal of post-nasal growths should be attempted, unless the instrument be guided either by sight or touch." I know it is not so easy to manage digital exploration with a shar])- cutting instrument, still I try to combine the two as far as possible, and therefore operate with Gottstein's knife, with the patient in the same position as that adopted when the forceps are used. If the growths also spring from the lateral aspect of the cavity, this knife is not suitable for the removal of tliis portion of the tissue. You will find the forcej^s come in there best. As to Meyer's ring knife, there are many cases in which it is impossible to use it. We so frequently find the nasal cavities small and ill-developed, as a result of post-nasal growths, that in a large number of cases they will not, even after cocaine has been used, admit this knife ; or frequently you will find one nostril admit it, and the other too narrow ; you can then put a curve on the instrument, and manage to reach a good portion of the roof. When you get it into the cavity, it is a sjilendid little insti-ument to scraj)e away all remains left after the forceps. Trautmann's sharp spoon I have used ; but I think with it you will find it hard to reach the anterior part of the naso-pharynx, as the diameter of the instrument is so great. AURAL DISEASE AND EPILEPSY. By C. L. M. Iredell, M.R.G.S. I approach the subject of the relation of aural disease and epilepsy with the greatest possible diffidence, feeling, as I do, that I can only "bring to bear upon it some little practical experience, tending to show that the relationship is causal, but wanting those refinements of research that belong more properly to pathology. It is extremely interesting to me to trace as I can the gradual manner in which the importance of aural disease in its relation to brain disease has become recognised. The significance of chronic disease in this region has, in fact, only forced itself into prominence during the last few years — say fifteen. It was generally understood that oeca.sionall}' severe inflammatory conditions of the middle ear resulted in ab.scess within the cavity of the cranium, but that this occurred from, or was in any way connected with, that state known simply as chronic discharge from the ear, was not accepted ; and, indeed, not infrequentiv was it con.5idered as the direct result of any treatment that may have been adopted with a view of checking such discharge. That all this has been changed may be best seen from the fact that the larger insurance companies now positively refuse to accept any one 790 IN'TERCOLOXIAL MEDICAL CONGKESS OF AUSTRALASIA. having a discharge from the ear, though this is clearly a mistake, as considerable discharge may exist without any perforation, and perforation may exist for lengthened periods without discliarge. It is, however, to the more obscure and less immediately fatal condi- tions that I would now allude. Fearing always lest one should come under the charge commonly made against specialism, of considering every condition as Vjeing one immediately connected with one's subject, I feel that I have neglected to take sufficient notice of many valuable instances liearing upon this matter. So much do I feel this to be the case that, while I have largely before my eyes quite a number of cases, I have preferred to illustrate my paper by some three or four which have come under my observation during the last two years. These, which I think fairly typical, have offered themselves since 1 have more particularly considered this subject. I have no doubt that much of the obscurity which surrounds this class of disease arises from the difficulty that exists in obtaining sections of this portion of tlie cranium. Nor, indeed, has it been the custom to look at all carefully in this direction, except in those cases where there has been reason to associate the cause of death witii caries or abscess. It therefore follows, that much of that which I have to advance is hypothetical, and open to correction by further investigation. In the introduction to I?}rom Bramwell's liook on " Intracranial Tumours," I find the following :— " The lirain and its membranes are favourite situations for the formation of new growths. In no other situation in the body is such a great variety of tumours met with ; it would almost indeed seem that the delicate and soft brain-tissue, richly supplied as it is with blood-vessels and lymphatics, is as fine a forcing and feeding ground for new growths, as Koch's nutrient jelly is for micrococci and allied organisms." Speaking later on of growths result- ing from injuries, he says: — "The explanation is probably this — that the blow produces a local inflammatory lesion or contusion, which forms a suitable nidus for the development of tuljercular germs, which are alread}^ circulating through the system." Now let us consider. AVe know that acute inflammation of the middle ear will give rise not only to the formation of pus within the cellular arrangen)ent of the temporal bone, and so sometimes by a direct process of destruction to thrombosis of the lateral sinus, as may be seen in a very interesting specimen shown by Professor Allen ; but it will give rise, without any intermediate course of destruction, to suppuration in almost any of the lobes of the brain, including the cerebellum. New let us assume, for the sake of argument, the existence of an irritation acting upon an otherwise healthy brain, falling short of inducing supjiuration, and continuing for any length of time, or lieing repeated as it would probably be in the case of chronic ear disease. What would be the etiect '? Quoting again from Byrom Bramwell's book, I find he says : — " Irritation of grey matter gives rise to symptoms, while destruc- tion of gre}' matter is often unattemled by any external manifestations" (page 9). I am so thoroughly alive to my deficiency in the scientific knowledge of these obscure aflfections that, even at the risk of weariness, I must again quote from this author : — " Theoretically, a tumour or other ' coarse ' lesion may cause discharge of motor gi'ey matter, either by AURAL DISEASE AND EPILEPSY. 791 'directly' irritating it, or imlii'Dctly (1) by interfering with the nutrient sui)ply or (2) by refiexly irritating it. Further, Duret has shown that spasms and convulsions may be })rodnced by irritating sensory nerves in the dura mater ; but the spasms which are produced in this way have not the well-detined and characteristic features of the localised epileptiform convulsions due to irritation of the motor cortical centres." Having considered these remarks, 1 would now ])oint out a pheno- menon presenting itself in the treatment of aural disease. It has occurred to myself more than once, and I have frequently seen it in the cliniques at home, that the simple act of syringing an ear, unprotected by an imperforate membrane, will produce symptoms varying from a slight dizziness to total insensibility. I would wish to say that, in the latter case, the water used was always, so far as my memory serves me, by inadvertence or ignorance -cold. However, there was no mistake about it — the patient dropped senseless on the floor. It not infre([uently happens, even after the most careful syringing with water of a ])ro]ier temperature, that the patient will complain of considerable giddiness ; and this will be within the experience of all of those interested in this sul)ject. How does this compare with the following case 1 Case I. On September 1.3, 1886, W. E. R., a^t. 17, was brought to me by his father, a man in good position and extremely intelligent. He com- plained that his son had had a running from the left ear for many years, and had had various advice, but had never as yet consulted a specialist. The young fellow was a fine, strong, well-grown youth, and had no other ailment whatever. I syringed the ear, which contained much discharge, and on examining it found a snudl polypus ; but as some water remained in the ear, its definition was not good. I therefore prepared, as is my custom, a probe armed with cotton wool to dry it, and proceeded to do this very gently and carefully ; but immediately, I noticed a tremor pass through his frame, facial muscles twitching, and l>efore I could interfere, he had fallen backward in strong epileptic convulsions. This seizure went through the oi-dinary phases, and in a short time he was recovered, feeling somewhat weak, but with an entire unconsciousness of all that had passed. The father was greatly alarmed, and assured me most positively that his son had never before had any symptoms of the kind ; and as I have never seen the patient from that day to the present time, I have no doubt that the whole thing was put down to my credit, as will probably be any subsequent turn the disease may take. Here we have an example of a condition distinctly epileptiform, following upon irritation of the peripheral ends of nerves in the tympanum. It is possible, howevei', that the case might bear another intei-pretation. AVe know from experience, that polypus in this situation is very generally associated with caries of the pars peti'osa ; and Ferrier's experiments have shown that the centres for the depressoi\s and elevators of the mouth correspond nearly to this portion of the temporal bone. Assuming that in this case caries existed, direct irritation of these centres by the carious bone may have contributed to the production of the symptoms. 792 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. The next case I would offer you is more iiiteresting, showing, as I tliink, the benefit derived from treatment. Case II. On June 23, 1888, I was consulted by L. S., a little girl a^t. 13. She had a polypus, and considerable discliarge from the left ear, tliis discharge having existed since she had had scarlet fever, at two years of age. It was for this condition that she was placed under my care : but as there was also some suspicion of mental disease, she was at the same time under the care of Dr. Grant, who considered her state as being anything but satisfactory, and feared de^■elopment of mental trouble. She had curious ideas upon many points ; had a habit of counting and repeating things a given number of times, and also was subject to tits of morose temper ; altogether, a state whicli, as I said before. Dr. Grant feared might presage mental derangement of a more serious character, but which he said was also not infrequently found in the subjects of epileptic disease. The polypus was removed, and subsequent treatment lessened or nearly removed the dischai-ge. Some months later. Dr. Grant had a letter from the friends, who lived in another Colony, saying that the little girl was very much better, the discliarge from the ears had entirely disappeared, and the fits of temper Avere much less frequent, and more controllable. Very shortly after this, that is to say — Case III. On July 30, I was called into consultation by Dr. Willmott, in tlie case of a little girl A. G., a^t. 9, with the following history : — She had had discharge from both ears from the age of 2 or 3, following no particulftr illness ; but during the last twelve months, the child had sliowii symptoms of what they feared was mania ; and as it was particularly noticed that the paroxysms always followed increased discharge from the ears, while subsequently, and in the intervals, the ears appeared to discharge less, or not at all, the parents concluded that there was some connection between the ear trouble and the brain symptoms. With this history, I proceeded to examine the ears, and to do so, syringed them first with warm water. Almost immediately afterwards the child became violent, trying to get out of bed, and although easily restrained, was evidently labouring under intense mental excitement, writing furiously and aimlessly across a copy book. At tlie time, I gave it as my opinion that there must be some further mischief than would be accounted for by tlie ear- disease ; at the same time, I ordered such treatment as was suitable to arrest the sub-acute inflammation tliat was going on within the cavity of the tympanum. 1 heard some time afterwards, that under this, the discliarge ceased ; that the paroxysms became less frecjuent and severe, but still continued until some weeks ago, since when there have been no cerebral attacks. The following case, I think worth including here, as evidently bearing upon the connection between the ear and the brain, but lieing unaccompanied, so far as I could judge, by any active disease of the former organ. AURAL DISKASE AM) EPILEPSY. 793 Case IV. On Sept. 6, 1S8S, Mrs. L. consulted nie, coniplaiiiinreface, I may say that a healthy adult, 25 years of age, usually hears the watch I employ at about 100 inches distant. Healthy persons over 50 years of age hear it at distances varying from thirty-six inches to nil. Old persons, hearing it at one inch or less, often possess perfect hearing power for conversation. My observations are not yet complete, but I do not think the acutenessof the hearing for the watcli diminishes greatly till at least the 40th year is reached. Where the redness was well marked, the malleus is referred to as being red. Where it was not well marked, the colour is described as reddish. VALUE OF REDNES.S OF THE ir.VNDLE OF THE MALLEUS. 795 -Hearing, lei pale. -Hearing, uallei aud or twenty- •" ^^" il u J? 0) 00 5 .a*tj 1,1 1 2 1 3 to § a s • - « 'C 'S "3 .5 3 a 5 "a o a ..a"S - -5 , ii aj 0) 3 ^ 'n .0 ^53 1 a ^ ,r as a^ » u n cS a c3 "^^ ;2 ^1 =4 „ CS 2 eS &. S- 2 OJ > •- 3 2 K •- J, 0) -5^3 « 3 Jo > ^ u o2 0-. 2 ^ O .u O -^J 2 Si g .If o ^ § § .2 2 -S S s *- o ^-2^ 3 t^ -if £ 3 3 ^- 22 > 3 OJ a ■" ■ '^ ?J 2 CO aj « ^ ii s a ^ s a «« «.- o •M =". < < O <) a - ro , Hm .- -M >-0 k^ z s rC *^r3 -L^r ,3 ^-2 _u'S ~tJ" — S -^ -4^ J -J" "t^ "^ "tn ^ s .SfS.S.'^'S .£f ■■S .SP"-S .ST ^.Si= "S .;^ "0 .H-C--^ Td'&o "5b n^ KiJS^q « H^i c^ ^q P^ ^ Ph 1-5 « i-:i ^y^ • ■-' cu Oj ss s • — . — — , — - ■ — — •• — . — • — — '■ — — • — ,— — . — • U ii £0 U f- %* ^ T~r ^ ^ i ^ ;-< ;h 03 ce y^ eS cS c3 o3 ':i 2 «S c3 ^ -S cj cS 0) a> .S (U a) (B '?, ^ a « GO: aj ® «^ QJ -, '^ s >j >j >-, t»J >M 3 p; ^ '^ '^ 5< "M -*< O -t* i-H c- "-■5 1?) -!* Qa 1—1 i-H i-t i» si O S5 C^ '-D ■■** r^ X -H •-3 ^ CO eo 1.0 -f -H M ■M — -M .H TC -M ■M •0 IM (M ■M "^ ri •?! ^<2 d iH SQ CO -* 10 C~ 00 o> rH ■M M •* O Z -H r-l 1-1 iH i-H I-H 796 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. An examination of the cases recorded show : — (1) That in all cases the red appearance was co-existent with deficient hearing power. (2) That in cases 1, 2, 4, 11, and 15 (cases which were kept under obsei'vation), improvement in hearing was coincident with disappearance of the redness. It seems to me that these observations warrant the ■conclusion that the redness is indicative of an inflammatoiy condition of the tympanum, which reduces the hearing power, and that it is distinctly a pathological sign. Case 1 furnishes a type to which attention must be called. There had been for two years positively, and probably for a much longer time, •chronic inflammation of tlie middle ear, which had steadily reduced the hearing power. On the disapj^earance of the redness under treatment, the hearing improved from two to ten inches right, and from three to live inches left — a considerable improvement. But yet this result was pool'. That is to say, the previous attacks had reduced the hearing to about ten inches right and live inches left. The redness was due to an additional attack of inflammation, from whicli the ear recovered. The table shows that redness is a hopeful sign to some extent. When the malleus appears i"ed, the hearing power may generally be somewhat impi'oved. PHLYCTENULAR CONJUNCTIVITIS IN ERYTHEMA NODOSUM. By Leonard W. Bickle, L.R.C.P., M.R.C.S., Mount Barker, South Australia. At the July meeting of the South Australian Branch of the British Medical Association, I read a short paper detailing the features of nine cases of erythema nodosum which had occurred in my practice since January 1884. In seven of these a condition of phlyctenular conjunc- tivitis was noticed, a number far too great to be a mere coincidence. Almost immediately after this paper was read, I met with a tenth case in a married woman, who had, in addition to the E. nodes on the leg, a well-marked erythema papulatum of the forearms, the rash being perfectly typical. In this case the same eye condition cropped up, and I was glad to avail myself of the services of a lady ai'tist, resident in tlie town, to sketch the condition. This sketch I now show, as it leaves no doubt as to the nature of the afliection. It is not a little curious that the symptom has not been noticed in South Australia as far as I can ascertain, and also, that it should occur in eight out of ten cases. Is the att'ection of E. nod. commoner out here than in the old world 'i The proportion of cases to those of general skin disease is intinitely greater in my experience than that shown by McCall Anderson's and tlie Amei'ican Dei-matological Association's statistics, and yet rheu- matism is undoubtedly rarer in Australia than in the older countries. The symptom is an interesting rather tlian an important one, and presented no difliculties in treatment, tlie dusting in of calomel, and NASAL CALCULUS FHOM A OIRL AGKD TIOX YKAHS. 797 a weak tonic lotion, causing a cure in a few days. It took place in patients of all ages, from ten }^ars to sixty years. The time of api^earance varied, in some cases coming with, in others later than, the rash. EXHIBITS. Dr. LiNDO FERCiUsox, F.R.C.8., of Duuedin, N.Z., exhibited tlie following specimens : — (a) Aspergillus niger. (b) Instrument. — A two-edged scissors for dividing the capsule. NASAL CALCULUS FROM A GIRL AGED TEN YEARS. By C. MoKTON AxDERSOX, M.R.C.S. Eng., Sydenham, Christchurch, N.Z. This patient was brought to me on Sept. 17, 18i>7. She was then suffering from an exceedingly offensive purulent discharge from the right nostril, which she had had for about one year. She was thin and pale, had a bad appetite, and was in very bad health. Up till a year preWous, she had enjoyed good health and spirits. I learned that she had been under medical treatment for about nine months, but apparently with no benefit. It was absolutely impossible to examine the nostril carefully, owing to the excessive (quantity and thick tenacious character of the discharge. I ordered a mixture of syrvip of iodide of iron with calumba, and a lotion (boric acid, gr. x in Jj) to syringe the nostril out with frequently. On Oct. 3, as the discharge had not improved so much as I had hoped for, I ordered the following lotion : — R. acid carbolic, Sj ss : acid tannic, gr. xij ; glycerini, ^j ; aq. ad. J xij, m. ft. lotio. Oct. 11. — The discharge was somewhat less copious, and not so offensive, but I still could not make a satisfactory examination. I then prescribed a mixture of liq. arsenicalis and dec. cinchona'. Nov. 5. — Considerable improvement in discharge and general health. Nov. 8. — Fancied the disease was located in inferior spongy bone, flopped this over with ecjual parts of carbolic acid and glycerine. This was repeated on tlie 12th, 15th, 21st and 24th Nov. On the last occasion I felt certain that I could feel some dead bone at the posterior border of the inferior spongy bone, and on firm pressure with a probe it appeared to move slightly. I then told the girl to come on Nov. 26th to have this removed, and that I would give her chloroform, as the nose was exquisitely sen.sitive, and a strong solution of cocaine seemed to have very little influence. I might here remark that, on the first occasion that the girl was brought to me, I had inquired most particularly as to whether she had 798 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. ever put anytliiiig up her nose, sucli as a pebble, a cherry or pluui stone, &c. But tlie child was quite positive on this point that she had not, and she seemed so clear and intelligent, that I accepted her denial. Nov. 26. — Chloroform having been administered, I proceeded to remove, if possible, this supposed piece of dead bone ; and after some owdered sulphur repeatedly till it disappeared, and the child apparently was all right in a few days. Not till some days after- wards, did she complain of inability to walk, and then to swallow, as when she tried to swallow it made her cough ])aroxysmally, almost to the verge of choking. She was almost completely ])aralysed ; she was unable to speak, to swallow, to hold her head up, and if it were held up, it would fall forward on her chest. The upper and lower limbs were almost quite powerless, the urine escaped involuntarily, and the bowels had not moved for days, and to crown all, she was quite cyanosed. 8he ultimately recovered. The other case is the one T have referred to so frequently, viz : — that of the young woman of 18, who had such a severe attack, with vomiting and epistaxis. Early in the course of the disease she had great difficulty in swallowing, and if anything solid were attempted, she would cough till she was almost asphyxiated. Tliis increased so rapidly, that all food had to be stojiped by the mouth. Treatment. In speaking of treatment, I have no intention to go into the different methods of treatment advocated by different authorities on the subject, but will simply give in detail the methods I adopted in different cases, with the apparent results, giving failures as well as successes. When I began to attend diphtheria, I did so with the unfortunate feeling, that to give perchloride of iron and chlorate of potash internally, and apply perchloride of iron and sulplnirous acid locally, meant a certain cure, and I entered comfortably on such treatment. This feeling one conceived from seeing records of men in ai)parently honorable positions and lai ge practices, such records being published with the view of showing that diphtheria was in the hands of such men a simple affair, in fact, tfiat if other men lost cases, they were morally guilty of culpable homicide. One man recorded 300 cases without a death. Lately, we have seen recorded sixty or seventy or eighty cases without a loss. Could one believe this possible, diphtheria would cease to be the dread disease which every conscientious physician believes it to be ; but when one sees records such as these, tliey either doubt the recorder's veracity or his diagnosis. In all cases, the treatment generally was what every one naturally resorts to. NOTES OX DlPIITriKlilA. 811 (1) Internal Medicines. Large doses of potass, clilorate and tinct. ferri. perchlor. were given internally, where it was possible to get it swallowed, but this was impossible in at least one-fourth of the cases, viz:— in children of very- tender years, and a few older ones, who struggled so violently that it was considered inadvisable, after one or two attempts, to force them to take the medicine. (2) Diet. The diet was in all cases, from the moment of seeing them, of the most nourishing kind. Milk, strong beef tea, chicken soup, and jelly, oysters, especially in adults ; and lastly, cream was administered in a number of cases where beef tea and chicken soup could not be taken, without causing nausea. Fortunately, as I stated before, the cases were nearly all in households where all these forms of nourishment were in abundance, and I feel certain that, had they been otherwise, I would have had a greater number of fatal terminations. I should have mentioned that switched eggs, with milk and brandy, were used freely. So fa»', the treatment mentioned is what is done by almost every medical man who is called to see a jtatient suffering from diphtheria ; but it is better to give every detail of treatment, so that the diff"erent parts of the treatment will have their own share of credit or discredit. (3) Local Applications. The first few cases in the first epidemic, I also treated by local applications to the diphtheritic patches and throat generally of liq. ferri. |)erchlor. and glycerine, one to four ; but although only two deaths occurred out of the eight so treated, I had the feeling that had I not used it in one of those two cases, it would have recovered also. The application caused such intense congestion and catarrh of the pharynx, spreading thence to the larynx, that I stopped it altogether in three cases after a few ai)plications ; and one strong girl of 12, who certainly was in a very low state before the last application, died from asphyxia thirty minutes after the application, her mouth and throat being full of frothy mucus. I then resorted to the local treatment advocated by Dr. Roliert Bell, of Glasgow, who claims to have had few, if aiiy, deaths in several hundred cases, viz., glycerin, acid, carbolic c liq. ferri perchlor. and acid sulphurosum. This did well in some cases, but did not pi-event death occurring in a case in which the treatment was carried on from the start. It also had the objection noticed in the perchloride application, causing intense congestion of pharynx, and profuse mucous catarrh. I then tried the application of carbolic acid. This I applied pure with a glass brush, painting the patches whenever they appeared in adults, and equal parts of glycerine and carbolic acid in cases of children ; then sprayed the throats every two or three hours with the following : — R Acid, carbolic. Jj, glycerini ^iv, aq. ad. jxij. The results were excellent ; where the case was seen early, and the patches destroyed at once, the disease was very much shortened, and in several cases the patches did not reappear. In fact, in two adults, the attack was to all intents and purposes aborted, that is to say, the pain 812 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. in throat, ear, and neck disappeared ; they picked up strength in a day or two, and were going about their usual occupations in a week. This last form of treatment I used almost as a matter of course for a good nximber with the nourishing diet referred to, and for a while with good results ; but at last one fatal case, followed by another, showed that even though excellent results from it were obtained, still that it was by no means to be looked on as a specific. It was at this time that I was attending the young woman referred to so frequently before. It was a most virulent attack, the fauces, tonsils, pharynx, &c., being, as I stated before, one mass of dirty greyish looking patches. I destroyed the patches with carbolic and glycerine, equal parts. The usual stimulating diet was ordered, and the spray of carbolic acid, glycerine and water ordered every two hours. Persistent vomiting set in, accompanied b}' epistaxis, and next day she was distinctly worse, dyspnoea being marked, and the face pale and anxious. The membrane had reappeared worse than ever, and she was soon in a critical condition, no food nor drink being retained by the stomach. I immediately resorted to nutritive enemata every two hours, the bowels to be cleared out once a day by an enema of pure warm water, each enema to consist alternately of two ounces of peptonised milk and beef-tea, with a dessert- spoonful of brandy in each. In desperation as to further local applications to the throat, and as tracheotomy would not be per- mitted, I thought I would try the solvent action of zymine, so I altered the spray as follows: — R Zymine 3ij, sodte bicarb. 3 ijj aq. ad. ^ iv, to be sprayed every two hours alternately with R Acid. carbolic ^j, glycerine Jj, aq. ad. J xij. Twenty -four hours afterwards, one would hardly have known the girl ; the throat had cleared to a great extent, leaving however extensively sloughed surfaces. The face was easy, and breathing much better. The vomiting and epistaxis had both stopped, and she was able to retain the enemata, which I ordered to be continued for other twenty-four hours. The spraying was to continue as before. Before giving up the enemata, the next day I tried if she could swallow, but she rather alarmed me by nearly choking and coughing paroxysmally. Soon afterwards, other symptoms of diphtheritic paralysis supervened, and I continued the enemata for about a week, adding liq. stryehnise m. v, three times daily. She was weakly, and not able to do mucli for over six months, but is now well and strong. This treatment of applying zymine locally, alternately with carbolic acid and glycerine, I have tried in eighteen or twenty cases, and in none of them was there a fatal termination. Whether this result was simply ]y)st hoc or propter hoc, I cannot say, l)ut theoretically zymine should be valuable in diphtheria, and certainly deserves a fair trial. Tlie other case of diphtlieritic paralysis I only saw after it had developed, and she seemed to me to be in extremis. I resorted to the same treatment, and she, after lingering for a little, slowly improved. (4) Inhalation of Steam and Eucalyptus. As to steam inhalations, I tried them in at least a dozen cases ; but from the cause I referred to before, viz., draughty houses, I was unable to continue them. The apparatus for employing the inhalations (which all contained eucaly})tus) was very imperfect, and no trained NOTES OX DII'lITHEIUA. 813 nurses being obtainable — consequently the orders for giving them not being correctly carried out — I was forced to desist. 1 would find the atmosphere in the room damp, the bed clothes damp, everything in the I'oom in fact damp, from rajnd condensation due to the quite too free ventilation. Tkaciieotojiv. Referring to tracheotomy, I only performed it on two occasions — one successfully, the other with a fatal issue. The first one I performed on the fourth day of the disease, and resorted to rectal alimentation every three hours, and the child was well in a fortnight. In the other case referred to, I was not permitted to do the operation till the child was choking ; even then the relief was so great that the parents regi-etted their obstinacy in not permitting it before. He lived twenty-four hours. I find that there is a great prejudice existing in the [)ublic mind, at least in the country, against tracheotomy. The parents generally say, " If my child is to die, it will die, but don't give it any more pain than it has already," and one cannot reason them out of it. This, I dare say, does not apply to the people in the city quite so much, for as a rule they have more education, and are more able to comprehend the increase of hoi)e of the child's life hy an early operation, compared to leaving the question of operation till the child is almost moriI)und. Summary. In summing up this rather fx-agmentary contribution, I shoidd like to draw your attention to the following points, which I consider the salient ones : — ^6- to Etiologi/. — I believe that in certain districts of this colony diphtheria is endemic. I ha^e pointed out already that it is endemic in my own district, and notably in some parts of it. I also have pointed out that it occurred in a much greater percentage of adults than is generally appreciated, and this I put down to the cause just mentioned, viz., endemicity. In purely epidemic di{)htheria (and I suppose this holds good in some other infectious diseases) very few adults are affected ; but oppositely, where the disease is endemic, I am convinced that adults run almost as great a risk as the children. Certainly their powers of resistance are greater ; and if diphtheria arises in the districts referred to from bad water, or malarious influences, the only difference in their susceptibility is their power of resistance, and the same, I think, accounts for there being no deaths among the cases in adults referred to. As to Season. — The four epidemics all occurred in autumn, when everything was burned up after the summer heat ; when the rivers were low, and their muddy banks were exposed to a hot sun ; when the air was dry and non-refreshing, full of dust, and probably particles of decayed matter ; and, which I think is, perhaps, more important than either of those just mentioned, when everybody was worn out by a long hot summer, leaving their staying powers very much below par. Two points in Treatment are worthy of note : — (1) Early rectal alimentation which is medicated by the addition of doses of liq. strych. 814 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA, suitable for tlie patient ; and m this, I think, we have the means of savino- many lives, especially in young children who won't swallow medicine, and won't swallow food for fear it contains medicine. This I would earnestly ask some of you to give a trial. 1 2) The local applica- tion of zymine as a solvent of the diphtheritic membrane. I am persuaded that, in the cases I have recorded, it did act as a solvent of the membrane when I could not get rid of it otherwise. The numbei- of cases I have tried it on are too few to pei-mit one to dogmatise ; but I would suggest that it may be a very valuable adjuvant to our para- phernalia of diphtheritic applications. As to the abortive treatment, by applying pure carbolic acid to the patch in the early stage, I fully believe that in a case seen early you can, in certain instances, shorten the duration of the disease. DISCUSSION ON DIPHTHERIA. Dr. Hayward (Adelaide) did not think that the constitutional symptoms were always secondary. He had seen the constitutional symptoms precede the local changes. With regard to treatment, anti- septics were necessary, but he preferred to give them internally. Dr. Nicholson (Benalla) did not think the disease was a local one. He had seen a case of diphtheria located in a boarding-house 'full of boarders ; he had sucked up the false membrane, and he did not regard the disease as being very contagious. The presence of albumen in the urine was no criterion in diagnosis. Dr. Appleyard (Tasmania) commented on Dr. Jamieson's paper. Dr. Curtis (Semaphore) said death rarely occurred in the tonsillar cases, but nearly always occurred in the laryngeal cases. He used turpentine internally and externally. Dr. Scott (Warmambool) regarded diphtheria as just as contagious as small-pox or gonorrluea. He strongly I'eeonnnended the use of eucalyptol or turpentine in the form of sprays. He feared that the use of carbolic acid tended to [)roduce pai-alysis afterwards. Dr. JosKE (Melbourne) had sucked up diphtheritic membrane in a tracheotomy case. Tiiree days afterwards his fauces and tonsils were inllamed and covered with false membrane, and he suffered from fever. He was ill for eight days, and recovered in fourteen. Dr. Hudson (Nelson, N.Z.) regarded diphtheria as a local disease. Membranous croup and diphtheria are identical. At the same time we must remember that it is not always easy to distinguish croup from forms of laryngitis. He preferred sulphurous acid as a remedy. Dr. WooLDKiDGE (Melbourne) said if croup and diphtheria were identical, then diphtheria had existed for a very long while. He was in the habit of removing the membrane mechanically. Dr. CoANE (Melbourne) believed that the local spread of diphtheria can be prevented by the application of a nitrate of silver solution, twenty grains to the ounce. DISCUSSION ON DIPIITIIEKIA. 815 Dr. B. J, Adam (Beaufort) used inhalations of eucalyptus oil in his practice. Dr. Newman (Geelong) referred to the strength of oil used. Dr. Spkingthokpe (Melbourne) said a large number of cases of "diphtheria" sent into the Melbourne Hospital turned out to be epidemic influenzal sore throat. Locally there was a deposit of mucus, simulating false membrane. In those cases in which the catarrh invades the tonsillar and epiglottidean regions, the resemblance was marked. It is probable that such cases, and also cases of simple catarrhal laryngitis, are called diphtheria in practice. Dr. J. W. Barrett (Melbourne) said it was quite obvious, from the remarks of speakers, that a distinction must be made between diphtheria and such affections as follicular tonsillitis on the one hand, and between diiihtheria and forms of laryngitis, attended with mucoid exudation (but not with formation of false membrane), on the other hand. Dr. Jamieson had related cases in which the inoculation of the diphtheric poison had pi-oduced diphtheria. Dr. Joske had related his experience in the matter, and he (Dr. Barrett) knew of a case in which a medical man succumbed to diphtheria brought on by sucking false membrane out of the trachea in a tracheotomy case. It seemed to him absurd to endeavour to refute the conclusion based on the exact and definite evidence adduced by Dr. Jamieson. This conclusion was that di])htheria could be produced by local inoculation ; the facts did not prove that it could not be produced in any other way. Dr. Jamieson, in rejjly, said that there were forms of laryngitis and of tonsillitis which are not diphtheria, but which are often difficult to distinguish from true diphtheria. These affections, probably, predispose to diphtheria. SECTION OF PSYCHOLOGY. PRESIDENT'S ADDRESS. By F. N. Manning, M.D. luspector-General of the Insane in New Soutla Wales, and Lecturer on Psychological Medicine in the University of Sydney. In taking this chair, I have first to acknowledge the courtesy and consideration which induced the Council of the Congress to select as the President of this Section, the senior officer of the Lunacy Department of the mother Colony, and next — it being my good fortune to occupy this position — to express my personal gratification at presiding over the First Session of the important Section of Psychological Medicine. The choice of a subject on which to address you required some thought and consideration. I could scarcely hope to say anything very new or very interesting on the more abstract and scientific questions pertaining to our specialty ; and remembering that this is our hundredth birthday, it occurred to me that I might, with interest to you and possibly with interest and advantage to those who may come after us, review our present position in regard to lunacy matters in Australia ; set up in fact a sort of mile-stone on which to record our i)Osition and progress ; and then, if time permits, indicate some of the steps which it behoves us to take on our path onward. I shall trouble you as little as possible with statistical details, beyond what are necessary to bring out and make clear the more salient and important facts, and shall relegate to an appendix various tables and returns, which are of considerable interest, and for the means of compiling which I am indebted to my confreres and co-workers — the heads of the Lunacy Departments in the various Australasian Colonies. The returns from New Zealand are given separately. It is much to be regretted, that the statistics from Western Australia are so imperfect as to be useless, except on one or two main points ; but I felt that I could not trouble Dr. Barnett for more details, after his statement in reply to my second letter of enquiry, that his "asylum work was merely an item of his general duties, and that he had no assistant." The first point I shall notice is, the proportion of insane to population : — ■ On December 31, 1887 (and I may mention here, that all the statistics I have collected go to the close of 1887), the population of the Australian Colonies was 2,951,590, and the number of insane, 8,435. president's address — SECTION OF PSYCHOLOGY. 817 There was, therefore, 1 insane person in every 349, or 2-86 jier 1000 ; the proportion of insane men being 1 in 330, and that of women 1 in 377 (Table I). There was considerable ditt'crence in the proportion in the different colonies (Victoria, 1 in 21)4 ; Western Australia, 1 in 351 ; New South Wales, 1 in 369 ; New Zealand, 1 in 380 ; Tasmania, 1 in 399 ; Queensland, 1 in 419 ; South Australia, 1 in 431), Victoria heading the list with 1 insane person in every 294, and Queensland and South Australia closing it with 1 in 419, and 1 in 431 respectively. The proportion in New Zealand was 1 in 380. The reason why lunacy is more prevalent in Victoria than in the other colonies, I must leave for your discussion, merely suggesting that the returns seem to point to a somewhat over stringent registration — patients on leave of absence being retained on the books for long periods. In the case of Queensland, there has been hardly time for the full accumulation of chronic cases — a process which takes some years. How does the proportion of insane in Australia compare with that in Great Britain and Ireland'^ On December 31, 1887, the proportion in the mother country was 1 in 342, or 2'92 per 1000 ; the range being from 1 in 316 in Ireland, to 1 in 346 in England (Table II). So that at present the burden of insanity in Australia is somewhat less than in the United Kingdom (1 in 349 in Australia, as against 1 in 342 in Great Britain and Ireland). Is insanity in Australia increasing in proportion to the general }»opulation ? I must answer this question in the affirmative, and add that the increase has during the last 10 years been only a slight one, and would appear to be due to the accumulation of chronic cases, and not to any })roportional increase in the rate of " occurring insanity." On December 31, 1877, the proportion of insane to population was 1 i]i 356, or 2-80 per 1000, as against 1 in 349, or 2-86 per 1000 ten years later, b}' no means a large increase, and mainly in the younger colonies. In the older colonies there was even some decrease. In Tasmania, the proportion decreased from 1 in 317 in 1877, to 1 in 399 in 1887. In New South Wales there was a slight decrease. The proportion in Victoria was practically unchanged. South and Western Australia and Queensland showed an increase — greatest in the latter colony (Table I). The admissions in proportion to the population, which show the ratio of "occurring insanity," were in 1878, 1 in 1550 ; and ten years later, 1887, had dropped to 1 in 1738 ; the average for the 10 years being 1 in 1690 (Table III). The nationality of the insane at present under care is of interest now, and will be of equal, if not of greater interest, to those who may examine our statistics some years hence. These statistics are not as exact as 2o 818 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. they might be, owing to imperfect returns from Victoria and Tasmania, in which the nationality of a considerable number is returned as " unknown " ; but they show several important facts, the chief among them being, that only 23'12 per cent, of the insane now under care were born in Australia, and that the larger proportion of our patients there- fore are of other than Australian nationality. Upwards of 26 per cent, are from Ireland, 23 per cent, from England, 6 per cent, from Scotland, 2 per cent, from Germany, and 2 per cent, from China ; whilst xmder the heading of "other countries and unknown," nearly 14^ per cent, are tabulated. Of these, about 5 per cent, come from countries other than tliose already specified, and include stray specimens of nearly every race and nationality. Those tabulated as " unknown " in the Victorian and the Tasmanian statistics, are evidently of foreign as opposed to Australian nationality, and by far the larger proportion should be credited to England, Scotland, and Ireland, and go to swell the already large percentages from these countries (Table IV). The proportion of patients of Australian nationality is, as might be expected, much greater in the older than in the younger colonies, and ranges from 12 per cent, in Queensland to 32 per cent, in Tasmania. No detailed census has been taken since the year 1881, and it is not possible therefore to fix accurately the relative proportion of the insane with regard to nationality; but there can be no doubt that the proportion of insanity is, throughout Australia (as it was in New South Wales in 1881), much greater among the foreign than among the native born. At that time, in New South Wales, the proportion of insane per 1000 among persons of British nationality, was 8-03, and among foreigners G'87; whilst among Australians, it was only 1-22 per 1000. The comparatively small proportion of insanity among Australians is partly to be accounted for by the fact that fully one-third of these are children, whilst insanity is mainly a disease of middle life and old age; but there are some reasons which I have not time to detail, which lead to the pleasant conclusion, that Australians are less subject to insanity than people of other races living in Australia. Turning now to the question of the recovery and death-rate of insane persons under treatment and cai-e, it is satisfactory to find, that with all the imperfections of Australian asylums, and the difficulties with regard to management which beset us, but from which the medical officers in English asylums are happily free, our recovery and death-rate compare not unfavourably with those in asylums in the mother country. Taking the decennial period from 1878 to 1887 (and statistics on these points are apt to be misleading unless they include quinquennial or decennial periods), the recovery rate in Australian asylums was 42-09 per cent., whilst in addition 6 "97 per cent, were discharged as relieved, as com- president's ADDKESS — SECTION OF I'SVCHOLOfiY. ^19 pared with a recovery rate of 40-04 j)er cent, in English asylums for tlie corresponding ten years. The recovery rate in Scotch and Irish asylums averaged a little below 40 jier cent, for the same period. It should be noted, however, that whilst the statistics of Australian asylums include idiots — a very incurable class — these are eliminated from the English statistics, and the Australian returns are therefore even better than they would at first sight appear. The death-rate in Australian asylums for the decennial period above mentioned was 7"09 per cent., whilst in England it was 9"58, and in Scotland 8-~)0. The death-rate in the various colonies was as follows : — Queensland, ')-S2; New South Wales, Gw2; Victoria, 7*11; Tasmania, 8'00; South Australia, 9-00. The New Zealand death-rate was 5'94 (Table Y). The returns from Western Australia are incomplete. The small death-rate in the young colonies of Queensland and New Zealand -is interesting in connection with the rapid increase of insanity in these colonies, and the difference between the Australian and English rate goes far to account for the somewhat rapid growth of insanity in all the Australian colonies as compax'ed with the mother country up to very recent years. The warmth and equability of our climate, which render our patients much less liable to pneumonia and other chest afiections than the insane in Great Britain, have, I think, more to do with the low death-rate than any other causes, and it is interesting to observe that, with one exception, the warmer and more equable the climate, the lower the asylum mortality. With regard to the classification of the insane, it ap])ears that of the total number 9 "So per cent, are suffering from undevelojied intellect — are, in fact, imbecile or idiotic ; 3"07 per cent, are under criminal dis- abilit}' ; nearly 1 per cent, are still at the charge of the Imperial Treasury — the relics of a by -gone regime — and 86 '59 per cent, belong to the ordinary class of the insane who have had intellect and lost it, and who are under no criminal ban (Table VI). Only 1188 of the total number of 8435, or 14-08 per cent, are deemed curable ; so that the large mass of our asylum population consists of chronic and incur- able patients (Table VI), The differences in the proportion of the various classes in the different colonies as shown in Table VI are interesting, but I have not time to discuss them or their probable causes. I should have Ijeen glad to discuss the question, •' Does insanity, as seen in Australia, differ in its forms and types from insanity in other countries 1 " but on this point I must content myself with placing before you one or two facts relative to general paralysis, a most interesting and typical form of insanity, which has only been fully known and recognised in modern times, and which is undoubtedly increasing in frequency. 2g 2 820 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. This peculiar affection is at present muck less common in Australia than in England. The proportion of general paralytics admitted to Australian asylums in 1887 was I'S per cent, of the total number admitted, whereas the proportion admitted into English asylums for the same year was 8-6 per cent. (Table VII). Again, the proportion of general paralytics admitted to the New South Wales asylums for the quinquennial period 1883 to 1887 was 3'4 per cent., whilst the proportion admitted to English asylums for the same period was 8*4 per cent. (Table YIII). This disease already appears more common in the older than in the younger colonies, and it will be intei'esting to observe if it increases in all. I may note in passing that as yet epilepsy is decidedly less common in Australian than in English asylums (Table YII). Time will not peimit of any lengthened notice of the lunacy laws of the Australian colonies, Ijut this is a subject which I cannot pass over altogether in silence. Each colony has its own Lunacy J^ctn, [)assed at various dates, com- mencing with that for Tasmania in 1858, and ending with that for Queensland in 1884, The foundation of all of them is English law and precedent. The superstructure varies with colonial needs and expediency. The scattered population, the paucity of qualified medical practitioners, the enormous distances, and various other matters, have had to be taken into account, and legislation adapted thereto. In all the colonies (except in the case of indigent patients committed by Justices in Tasmania and South Australia, where one medical certificate is accepted) two medical certificates are required before patients can be admitted to hospital. In all, patients can be admitted at the " request " of relatives or friends, if such request is accompanied by two medical certificates. In all there are stringent provisions, that the persons signing the " order," " request," and certificates shall be independent and nnassociated persons. In all there are provisions for the rejection of imperfect certificates; and in all, except Tasmania and South Australia, where there are special arrangements, the medical officer of the hospital must give a separate and independent certificate of insanity within a brief period after admission, or the patient cannot be detained. There are also in all abxmdant provisions for inspection by inspectors, commissioners, official visitors, or other authorised officials, and the interests of the patients are as fully guarded with regard to discharge as to admission. On the whole, the lunacy laws of the Australian colonies appear to be satisfactory, sufficient, and well abreast of the time. They are in no way behind, and in some respects ahead of the legislation in Great Bi-itain, tlie United States, Canada, and the principal European countries. PRESIDENTS ADDRESS — SECTION OF PSYCHOLOGY. 821 111 the provision of receptiou-liouses in New Soutli Wales and Queens- land, and of lunacy w;ird.s in })ublic hospitals in Victoria, for the treatment of insanity in its early stages, the Statutes are decidedly in advance of those of Great Britain. During the year 1887, the Master in Lunacy in New South Wales ap])lied to the English Courts for the payment to him of money belonging to a patient in one of the hospitals of the colony, and in delivering judgment* Lord Justice Cotton thus expressed himself : — " We have been referred to the Lunacy Act of New South Wales, and undoubtedly that Act contains provisions which make it practically ini[)ossible that anyone should be in an asylum without sufficient reason." Whilst Lord Justice Bowen said : — " I desire most emphati- cally to add my voice to what has been said by the Lord Justice as to the provisions of the Colonial Ijegislature, being above all comment and criticism as regards these insane patients. We have the most ample confidence, not only in the legislation, but in the officers who administer the law, and the patient is surrounded by all the protection and safe- guards that could reasonably be invented for the purpose of taking c^re of herself and her ])roperty." What is here said of the lunacy laws of New South Wales might, 1 believe, be said with but little reservation of the lunacy laws of all the Australian colonies. The newer Acts are, as they should be — the better. Our younger sister, Queensland, has been able to see the few weak points in the legislation of the older colonies, and avoid them. Whilst I am on this subject, I may mention that during the last three or four years there has been in England an outcry for the reform of the Lunacy Acts, and so-called reformers have advocated three I'adical changes : — (1) That no }>atient shall be sent to an hospital or licensed house, unless examined and committed thereto l)y a judge or magistrate. (2) That all such committals shall be for a definite time — say one or two years, and shall l)e renewed if necessary. (3) That all medical certificates shall be signed by specially a]ipointed medical practitioners or exjierts. I think there is reason for the strongest objections to each and all of the.se proposals. It is clear that they would widen the breach between the care and treatment of diseases of the brain and diseases of other organs, which for years all the teaching, all the endeavours, and all the wisdom of modern science has been endeavoui'ing to close and annul, and did time permit, I should, I think, be able to show that such legislation would be a retrograde step, and be able to give good and sufficient reasons for its rejection. ' Law Report, Chanceiy Div., Part 12, 1887. 822 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. As yet there is no special legislative provision for idiots and imbeciles ill any of the Australian colonies, and the English "Idiot Act of 1886,"^ entitled "An Act for giving facilities for the care, education, and training of idiots and imbeciles," might with advantage be adopted. In Great Britain, there are various methods of providing for the insane. Besides State institutions for criminals, and for the insane of the military and naval services, there are county, district, and parochial asylums, as well as lunatic wards in poor houses, under the management and control of local authorities, and the inspection of Government Officials ; lunatic hospitals under trustees, in which the excess payments of the well-to-do are used for the support of those less favoured of fortune ; private asylums, which receive j^atients at rates suited to almost all classes of paying jiatients ; a system of payment to relatives towards the support of the insane ])oor ; and in Scotland and other ])laces " boarding-out " with strangers who have no connection with, or interest in, the patients, except the monetary one. In Australia, with the exception of private asylums in New South Wales and New Zealand, the whole of the institutions for the insane are under State control, su})ported l)y funds provided by Parliamentary vote, and managed directly bv the Government, and there is no established system of payment to relatives, or " boarding-out." In Great Britain, with an elaborate system of local government, the result of long experience, the local or district provision for the insane leaves little or nothing to be desired. In America (where local govern- ment is less completely organised), whilst the State asylums are admirable, the institutions under local or municipal control are for the most part dismal failures. The fifth report of the State Committee on lunacy of the Commonwealth of Pennsylvania, published only a year or so ago, contains the following statement: — "The entire arrangement and government of many of the county institutions are such that the insane poor cannot be otherwise than neglected and cruelly wronged, and the treatment of this unfortunate class in poorhouses has been simi)ly that of continued neglect." The details given in this and other reports, from Pennsylvania, New York, and other States, aro simply horrible. [ see nothing in the present state of local government in Australia wliich leads me to think that municipal or county authorities would be any better guardians for the insane than they are in America, and I think our insane fortunate that they are, so far, wards of the State. It would lie well, however, if our State institutions were supplemented by others, like the lunatic hospitals at home, managed liy trustees for the good and profit of the ))atients only, and bearing the same relation to the sick in mind as our general hospitals do to the .sick in body. PRESIDKNT's address — SECTION OF PSYCHOLOGY. 823 As yet, private benevolence lias not stepped in to assist in tlie maintenance and care of the insane in Australia. We have no insti- tution.s like the Maclean Hospital in Massachusetts ; the Pennsylvanian Hospital for the Insane at Philadelphia ; the Hospital at Cotoii Hill, near Stafford ; Barnwood House, near Gloucester ; the Friends' Retreat at York ; St. Andrew's Hospital, Northampton ; the Holloway Sanatorium at Virginia Water ; Murray's Asylum at Perth ; the Crichton Institution at Dumfries ; or the several Royal Asylums at Edinburgh, Montrose and Glasgow, and other cities. I mention these as types of many others in Great Britain and America, all of them magnificent institutions, built or endowed by private benefiuence, for the care of patients who are not able to meet the charges for main- tenance. In tiie small New England State of New Hampshire, upwards of <£54,000 has been bequeathed for the benefit of the patients in the State asylums, and the interest is now expended by the trustees for their benefit. This is by no means an exceptional instance in America ; whilst, so far as I am aware, not one penny of private means from subscriptions, donations, or legacies, is available for the maintenance of insane persons in this great continent. I trust that such an opprobrium will not long continue, and that ere long, the sick in mind may share with the sick in body in the contributions of the benevolent. I know no way in which the surplus wealth of the rich can be better expended. I know no way in which more real solace and comfort can be afforded, and a truer charity exerci.sed, than in placing in a position of comfort the minister of religion, the physician, the artist, or the teacher who would, except for such aid and assistance — owing to the loss of all means through a cruel malady — be left to the charity of the State, and have to herd with the vagi-ant and the pauper, though still retined, still cultured, still with tlie instincts of a gentleman. Again, though I am no advocate for private asylums, I think these institutions — for the richer classes — have a useful place in an asylum system, and can make provision for those who cannot he so adequately cared for under the, perha[)s necessary, restrictions as to outlay in Government institutions. Until within the last few years, all the hospitals for the insane in Australia received all classes, and wei'e in no way specialised ; but with the growth of population, the wi.sdom, nay, the necessity, of providing .separate acconnnodation for criminals, for idiots and imbeciles, and for the large class of chronic in.sane, has been recognised. New South Wales, Victoria, and Tasmania have already, practically, distinct institutions for criminals. In New South Wales there is a sepai-ate hospital for idiots. In Victoria and Tasmania these classes aie 824 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. placed in cottages — separate from, though in connection witli, the hospitals — and the Victorian Government, to its great honour, has lately made a distinct step in advance, and commenced a system of special education and training, after English and American models, for this feeble-minded class. The much-debated subject of the separation of the acute and chronic- insane, by placing them in different institutions, has found a practical settlement. At Parramatta in New South Wales, Sunbury in Victoria, and Ipswich in Queensland, buildings erected for other purposes, and uiisuited for the more demonstrative classes of the insane, have been set apart for chronic cases, and there can be little doubt but that this arrangement will be more fully carried out in tlie future, as tending to economy and more systematic classification. The system under which all patients who are brought to our hospitals in all the Australian Colonies are admitted, whether there is room or not, is one that, so far as I am aware, obtains in no other country— certainly in no other English speaking community. In Great Britain, in the United States, in Canada, a standard of accommodation is fixed, and no patient is admitted in excess of this. In Great Britain, the numbers in excess of the accommodation in local asylums are accommo- dated temporarily in the asylums of other districts, in licensed houses or poor-houses. In Canada and the United States, the temporarv accom- modation ])rovided is in poor-houses, or other receptacles, and the patients must await their turn for admission, should the State asylums be full. Our system has one advantage, it gives us our patients in an early, and in many cases curable, stage of their malady ; but it has disad- vantages which outweigh this. It does not allow us to do our best for them when we have got them. Our accommodation (I speak from twenty years' experience) is seldom or never in advance of our needs. It is often grievously behind them ; and the over-crowding consequent on this is .subversive of all order, cramps, if it does not paralyse, the best efforts of our medical officers, and is too often fatal to the mental health of our patients. If this system of admission is to be continued, it should be in connec- tion with one for providing more sjieedily, and under less restrictions than at present, ample and suitable accommodation — and this, gentlemen, I fear, will never be until the management of our asylums is placed in the hands of persons (a Commission it might be — these are the days of Commissions) who will have more weight, and be more listened to by the Government, than any single head of a department, even if an embodied importunity, can hope to be. I think I have riot been remiss in urging the claims of the insane in New South Wales ; but the accommodation in that Colony is still far short of what is necessary to president's address — SECTION OP I'SYCIIOLOGY. 825 give 600 cubic feet per patient — the least space necessary for liealtli, quiet, antl efficient atlministratioii ; and I gather that tlie same condition of things exists in other colonies. Some of the buildings in use for housing the insane in Australia are strangely diflferent to what they sliould be, and require improving off the face of the Continent. Thei-e are some in Tasmania, in Victoria, and in New South Wales, which are heart-breaking tg those having oliarge of them ; but it is to be hoped that these will soon be things of the j)ast, and the line piles at Kew in Victoria, at Parkside in South Australia, at Callan Park in New South Wales, at Toowoomba in Queensland, and at SeaclifFe near Dunedin in New Zealand, are evidences of a large and wise liberality, and an earnest of advancing civilisation. The number of medical officers to patients in Australian asylums is at present far below what it should be. In the United States, it is 1 to every 160; in Ontario, the foremost State of the Dominion of Canada, 1 to 209 ; in Great Britain and Ireland, 1 to 250 ; in Australia, 1 to 325. I understand that arrangements have been made in South Australia to commence this year with one additional medical officer, and the New South Wales Parliament has provided n)eans for the employment of two in addition to the present medical staff. Under disadvantages, some of which I have indicated, we may, I til ink, be proud that non-restraint in the treatment of otir patients is' our rule — restraint the occasional exception. From the returns fur- nished to me from all the Australian and New Zealand asylums, it appears that restraint is on an average used only in 1 out of 300 or 400 cases, and then chiefly for surgical reasons, or to guard figainst suicide. Thus much as to our present position. And now, turning from the present to the future, what are to be our further onward steps in the care and treatment of the insane, and in the advancement of Psycho- logical jNIedicine ? To the amateur alienist — at all events in Victoria— the great desideratum would seem to be the leplacing of what are some- what unfairly called barrack buildings by cottages ; and if one is to trust newspaper reports, the Government of Victoria is aViout to take the astounding step of housing some 1500 insane patients in cottages, and placing this •' City of the Simple " at some distance from the metroi)olis. The objections to this sclieme have been so ably set forth by Dr. Barker, an officer of the Victorian Lunacy De])artment, that it is perhaps not necessary for me to go fully into the subject. Something, howevei', I must say on this point. 826 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Whilst I am very decidedly of opinion that cottages should form a part of every Hospital for the Insane, I am also of opinion that tliey cannot be very largely used, and that for three-quarters, if not nine- teuths, of the insane under hospital care, cottages will be found alto- gether unsuitable. They are costly to build, costly to work, difficult to administer and supervise, and add little or nothing to the comfort and well-being of the patients placed in them. The truth is, that the Iarg& majority of patients when fit for cottages are fit for discharge. For convalescents, for certain of the chronic insane - especially the steady workers who do so much to carry on the farm and garden operations of all hospitals — cottages afford a comfortable and suitable home. For the sick they are unsuitable, as withdrawing them too much from efficient medical supervision ; for a great majority of acute cases, for the excited, dangerous, and turbulent, they are unsafe ; and for the chronic dements, the dirty, the paralytic — who make up so large a part of all asylum population — they involve too much expense, and too extended a supervision, without any commensurate re.sult. Let us have cottages as part of our hospitals by all means. 80 far as the hospitals under my su[>ervision are concerned, I could wish for a decidedly larger proi)ortion of this class of accommodation, but I do not anticipate any great amelioration of the condition of the insane by this means, and if the official programme is to be carried out in Victoria, I fear it will be a costly mistake. The truth is, that no one form of building can meet all the needs and requirements of the insane. Cottages alone will be as unsi\itable as " barracks " alone. What is required is variety in the construction, arrangement, and position of the buildings of an asylum, so as to allow of judicious segregation, and to provide for the wants of [nitients of difterent classes. If I am to indicate briefly what I consider the best form of asylum ; what it is desii'able that the Psychopathic Hospital of the future should consist of— I should stipulate for a central lK)Sj)ital for the sick and for acute cases, surrounded by pavilions or blocks of varying form and construction for different classes, and supplemented by cottages for the convalescent, the quiet, and for certain chronic cases. The buildings should stand on a large estate, and be spread over a considerable area. They should contain abundant space^ with light, airy, cheerful day rooms, large verandah.s, and well-ventilated dormitories. It is essential that a quarter, at least, of the total accommodation should be in the form of separate or single rooms. It is important — at all events in our climate— that the day rooms should all lie on the ground floor, so as to afford direct and easy access to the verandahs and the open air. It is even more important that the blocks or divisions should be comparatively small, so as to preveiit too large an aggregation of patients, and sufficiently numerous so as to allow of a PRESIDKNT'.S ADDKESS — SECTION OF PSYCHOLOGY. 82T varied classification. These are our main requirements, ;ind I would point to the Eastern Hospital for the Insane at Kankakee, Illinois, as perhaps the best existing model. Special architectural forms or styles are but of secondary importance, but T would plead for space as against outside ornamentation, which is too often only a mockery of the misery within. The boarding-out of pauper children has been so unqualified a success^ that it has been assumed that the boarding-out of pauper lunatics is likely also to have good results. The lunatic colony at Gheel, the boarding-out at Kennoway and other places in Scotland, are each in their way interesting and encouraging experiments. The system, as tried to a very limited extent around the Sussex County Asylum, and at other places in England, has not been without good results; and it must not be forgotten that there are in England upwards of GOOO out-door pauper lunatics, or upwards of 7 per cent, of the total number of the insane, mostly living with relatives, and i-eceiving weekly relief from the guardians out of the poor rates; but that it will ever be in Australia a method of providing for any large number of the insane, I very much doubt. I do not propose to discuss the question at length, as it is the subject of separate notice in a paper by Dr. Beattie Smith, but I would point out that with children there is increasing growth, increasing usefulness, increasing intelligence, to appeal to the feelings of their foster jtarent; whilst with tlie lunatic, there is none of these things, and the conditions are altogether different. To subsidise, assist, and encourage the friends of the chronic insane to keep them at home, or to i-emove them from hospitals when fit for such removal should. I believe, be part and parcel of our asylum system, and in time I believe a very considerable number will be kept in their homes by means of State, parochial, or municipal aid; but whilst wages are high, and there is much scope for active employment, the number will not be large. The antecedent conditions which have rendered Gheel and Kennoway possible — a large waste of poor land, and a miserably poor proprietary who are glad of the added pittance to eke out their want of means — are things which none of us can wish to see in Australia. The well-to-do condition of our working classes renders the boarding-out of the insane (by which I mean paying strangers to receive and take care of them in their homes), at present at all events impracticable, even if it were desirable; whilst the absence of village life, the isolated dwellings, the sparse population, the special dangers and ditiiculties of " bush " life, and the impossibility of effective medical or parochial supervision, all stand in the way of an adoption of the system, except in very special and occasional cases. 828 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. The separation of the idiotic and imbecile from the insane, both by legislative enactment, as T have already indicated, and by the provision of special institutions in which they can be trained and taught, is a matter of very considerable importance, and will, I have no doubt, be undertaken in all the colonies as soon as the number of these patients in each justifies the expense necessary for the special provision. The memorandum of the Committee of the Charity Organisation Society, agreed to at meetings held in London in 1877, has been virtually adopted bj^ all who have thought on, and worked at, this subject. In a few more years, when the number of the criminal insane has increased, the wisdom of making provision for this class in sei)arate buildings, if not in separate establishments, will, I have no doubt, be acknowledged and acted on in all the Australian Colonies, as it has been in England, Scotland, Ireland, in the State of New York, and in New South Wales, and provisionally in Victoria and Tasmania. The further question arises, whether such provision should be in connection with the Lunacy or the Penal Department. Those patients who are acquitted on tlie ground of insanity, who are insane first, and whilst insane and irresponsible, commit criminal acts, may faii'ly and properly be placed in wards or establishments in connection with the Lunacy Department ; but so far as I can understand there ai-e no valid reasons why -arrange- ments should not be made for the treatment of those who become insane whilst undergoing sentence — who are criminal first, and insane after- wards — in connection with the Penal Department. When prisoners undergoing sentence suffer from bodily ailment, they are treated in properly provided hospitals in the prisons. Why should not provision be made in ^^I'isons also for those suffering from mental ailments and brain diseases 1 Suitable buildings should not be difficult to provide. The prison surgeon should be as well qualified to treat diseases of the In-ain as of other organs, and the gaol warder has special qualifications for dealing with this special class. The transfer and re-transfer of these patients from the Penal to the Lunacy Department is a constant difficulty and ti'ouble, the system leads to malingering and to numerous other difficulties in both departments, and it tends to make our asylums into prisons. The practical wisdom of the Scotch has solved the question by establishing wards for criminal lunatics in connection, not with an asylum, but with the general prison at Perth ; and an interesting experiment at Woking Prison in England, where all the insane convicts have been kejjt during the last 11 years, has been reported on at length by Dr. Cover in an apj^endix to the report of the Director of Convict Prisons for 1885-86, and has proved a substantial and gratifying success. The most desirable and necessary onward step, as it appears to me, is a more extended, largei-, and more accurate scientific study of insanity. pkksident's addrkss— section of psychology. 829 More extended with regard to the medical profession at large. Larger, more accurate and scientific, so far as those especially engaged inasylnm work are concerned. I think I am not over-stating the un ^g the liecovei For tlie year ( Dee. 31, 188^ For the year 1 1 Dee. 31, 188: ' For the year ■ 1 Dec. 31, ISS: For decennial [ ending Dee. 3 1 For decennial ( ending Dec. 3 f For decennial ( ending Dee. 3 j For the year > I Dee. 31, 188: ( For decennial ( ending Dec. 3 PERCEN"TA(;t;. .lale. Female. Toi 7-31 10-40 8- 0-65 8-08 9- 4-01 12-15 13 6-31 9-06 7- 8-80 7-64 8- 8-98 21-42 19 9-32 9-39 9 5-76 12-92 14 ,,„ SItl uH^mto'lSW. 1 ilt?*^mb«r!'^7t' "" Bit DwmiUr, l»7. * Oft IteWBbtr, ^K^. C.U,,,. Ihlf. nuM,. T«l»l ] Mn)» [F.mia* w j «.,., ; i^.».. 1 To.^. I »«!. P.I.I.I.. j Tutal 1T*1 - Sow South Wslet^ 5TJ.D1S 408.HU7 ' 1.013,1110 : l.TSfi 1.D80 650,1150 48Q,0G0 I.O^lG.llO 1,866^1.638 3U.5SI 1 i.-.2,«o auo.nio m 330 71.7^4 j r,5.0Hl l«-,..8« 1 IDS 167 3.831 3,610 3-42 per 1000. 3-35 iier 1000. 350 per 1»00, 3-19 per 1000. 3'58 per 1000. 3-41 pvr 1000, »-18 per 1000. 337 per 1000, 2-71 per 1000. | H-13 p« 1000. 3-30 'i«r 1000. 3'68p°rl000. 1 in 294 1 1 iu 371 3-31 pur liXK). ' 3-11 per 1000, 3-38 por lOOO. , 3'03 per 1000, 2-50 per I'oOO. 3-7» per 1000. 1 in 309 1 I ii?3Ul 1 iu Jll 3-7G pur 1000, 2-01 per 1000, 3-15 'per 1000, T.„,. .. 1.006,530 ! 1.;MS.070 2.051.3W , 4.868 3,507 8.435 j 303 per 1000, 305 per 1000, 3-68 pM 1000. ; SWt per lOOO. 2-53 per lOOO. 9-80 per 1000, 1 ""■ ' '''""""°" ■■ 3iT,!t08 , 297.933 | iU5,H;M I.U'.a 042 -1 3-03 per 1000. 2-16 per 1000, 3lia per 1000, i 217 p*r 1000. 1 in 330 1 1 iD 101 1 in 603 lE™ Shoiping the I'roj-orliou of Intanf to I'cj.Hialum i„ En^tam/, SaAlaml, and Ii-e/iind, on 3t»l Dttimber, 1387. r«,.«.o,. ^- ,„„, P™k,.». „, „,„,„„„. 1 1 «... FUD>I>. TcUI. link 1S.04S 5d.7«l M.M9 15,303 liD3I(l,or »p.,ll)0O linSa6,or ilSt EngUnd' .. 18.931,593 Ireland: „| u.m.m 3».^,Mi «r.floi Tor*!. .. .. .. 87,157,655 ' 30,720 109,513 TABLE III. Sin tie Pol ul t\o f tfie A tt al a C h m (/ \ nher of Patirult admitted to ihc Anjlum, and t/ie ProporlloH of AdmiMcms to Population for llif 10 i/iart. 1S7S to 1S87 imtui ».«, » » ,1 ii *.»•""■ T.^.,u. »»™,A„.,„„. ,7ir-. 3,900,lu^ 31,813.487 1.311 lit) 1,650 1.400 1 ill 1.633 U.G80 ; 1 in 1,690 1 A-Jimu /or tht Yenr ISST, 'lii:l fir llu Dmuttinl ! IhtuJm, 1SS7. ^^ " ,-Jt„ ■33 87-60 il-U 41 »« 2'fl9 3-18 3 33 43-70 61-31 46 ■79 8-111 5-10 7 72 e-57 3-26 7 41-00 57-W 46-99 49-6 00-00 40-01 4-3-C3 48-U8 45-(IO 3-60 5-47 4-22 46-19 6-1-40 i9-i-> 6-87 0-OU fl'68 0-42 4-93 S'83 0'59 53-16 45-W ' 4fl-8H JBS 1'06 { 43-64 43-00 i i9-\S 44-11 5-58 1 9-04 0117 I 7-57 108 New South IVulce TABLE VI. 'till/ l/u Clasiijica'Mn »/ the huaiie in (/«• AiMmlian Coloints on 32st Dfcen^i; 18S7. 'lU-40. S'GO I 8-08 no I 14-01 1 13-16 , 1«-B5 I 8-08 I 0-4 760 0-32 0-30 1 9-85 340 lS-76 : 13-02 14-00 ^ "■"--l 78 11 36 10 -909* 60 47 19 2-06 0-48 I 18-52 6-57 I 106 1 0-62 ..r- I i 00-31 0118 S54 1 83-85 n-U 193 ' 7e-19 ; 52-80 ' 70 I I 10-75 ' 7fi0 I 43 I 12-2S 307 i I 12 ; 0-91 lOfl • 1.188 114-08 7:^: Shumn'j th. uiiuiber of Bpilej}(ic4 uitJ Urmral I'aral-jd-:* o.imitUd Inio Auflmiiau ,l«y»HW .hirin.j ihr Ytar JUS?, D«le. :: 0-9 1887 1 SoulU AnVtrda" '.'. '.'. 1887 WMtern A?S:uS» 1 "■"• 1M4 i |M 5 yearn [ 1,581 '»"-j '"•'■'»-- "-^ ,«.! ».!.. k«.,., Tou, 1 ,„, 1 r„^ 1 ,,^ ,^ 1 „„,^ ,.„^ „^, «,^!-t- 178 [ ISO 16 . S 97ll9*69| 80 1 8 ~ fi.j ! '■* ; ^t i^^ "■"** 1 "-"IS 13.581 998 I 988 1,151 1 18-8 S.i ' A". ^'3 ! '*^ '■''" 7.441 1 14,458 918 1 912 l.IO*' ' 18-1 tn 1 7=1 i'l 1 ^**' '-**75 , 7.*3S 1 14.808 980 200 1.192 18-9 5-8 ! i-5 1 1-2 IS 1 !■")" ! "■"' '»■'«" »=" "^ '■!" ' i"'" ^ji^ ^^Ki^ ^9JI^ Iggi; ^ 0.712 1 6.912 [ 13.824 904 213 1.177 14-8 6-0 ] 0-8 1 3-4 11 6 j™,| 33,819 ;86J)17 '69.129 4.743 1 1,113 .,,835 140 3-8 ! 8-6 '^ 'J i:;|n 8. , 8- eiiiale. Total. i' 3 ,S-12 8-91 7 3')(r87 52-.52 lU-97 1 31-20 1 s-65 1 31I-S5 3 4-40 0-13 1 4-l('. ] 5-94 Total. 300 Sl-oB 2,8'21 200 90-93 3,ol9 750 874 350 121 .551 73-40 : 7hO H9-24 ;307 N7-71 ;i()9 90 08 j247 85-91 1 8,435 PRESIDENTS ADDRESS — SECTION OF PSYCHOLOGY. 833 two years at Gladesville, are more than gratified with the result, wliich to my mind is most satisfactory. The effort to improve the qualification of those in immediate attendance and care of patients, promises great lienefit to the insane ; and I am making no rash prediction in saying that, within another decade, no attendants nor nurses will be employed in State Hospitals for the insane in these colonies, except as probationers, who have not gone through a systematic course of training and instruc- tion in their duties, and received certificates of their fitness for their special work. Did time permit, I might go on to indicate some of the hindrances, the troubles, and difficulties which are known only to those who are engaged in lunacy work, but I should serve no practical purpose. Insanity, though a most interesting, will always be an unpopular subject, and one in which little or no outside interest will come to our aid. Most of the progress which I have indicated must come from within rather than from without, and though I believe that the care and treatment of the insane, and our knowledge of insanity, will steadily improve, and a more intelligent interest arise in our work, especially among the members of the medical profession, we shall in the future, as in the past, in only too many cases, and for some years to come, have to do perforce of circumstances what is expedient or possible, instead of what is right and best, and to be content, or as content as we can, with an attainable good, instead of an unattainable better. See Tables. 2h 834 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. A CASE OF SPORADIC CRETINISM, WITH REMARKS. By F. Norton Manning, M.D, Inspector-General of tlie Insane, N.S.W., and Lecturer on Psychological Medicine at the University of Sydney. The case I am about to describe is one of a somewhat rare disease — rai-e, at all events, in Australia, since it is the first and only one I have seen in an experience of twenty years, and not very common in Great Britain, though I have been able to find more or less full notes of twenty-six cases. In addition to these, I find two cases described bj^ M. Baillarger as having occurred in France. S. G. was admitted into the Hospital for Idiots and Imbeciles at Newcastle, N.S.W., in April 1888, and I obtained the following history from her father, who I may mention is a somewhat squat ugly Irishman, of quite average intelligence, and comes of decent stock in the West of Ireland : — He did not leave home till he was thirty years of age, and knew his own and his wife's people i;p to the grand- parents on both sides. He states confidently that there has been no insanity, idiocy, or epilepsy on either side, and describes his wife, who died about three months before the patient's admission to hospital, as a "very fine healthy woman." The patient is the last but one of six children, all the rest of whom are well-formed, healthy, and show no mental failure, and three of whom are married. The father describes himself as a sober, steady man, and I have no i-eason to doubt his state- ments.. There is no history of syphilis. The patient was born in Armidale, N.S.W., and is now eighteen years of age. She appeared healthy at birth ; at all events, the parents were not conscious of any- thing wrong with her. At eight months old, she was thrown out of a perambulator. After this convulsions commenced, and continued occa- sionally till she was nearly three j'ears old. They were not frequent, and were probably due to dentition. Tliere have been no fits since. The idea that there was something the matter with the child appears to have dawned very gradually on the parents ; but they were fully aware of her deficiencies before she was three years old, and the probability is that the malady, if not congenital, commenced early. She has lived for tlie last ten or twelve years in a suburb of Sydney, and was taken care of by her mother and sisters till the death of the former. On admission. — She was an excellent and characteristic specimen of a cretin, or cretinoid idiot — a case of true sjioradic cretinism. Her height was thirty-five inches, and her weight fifty-six pounds. The chest girth was twenty-eight inches. The figure was broad and squat, and there was considerable development of fat. The abdomen was protubeiant, and the legs bowed and twisted. The arms measured fourteen inches from the tip of the acromion to the finger ends, and the hands were large and wrinkled, and aged-looking. There were no signs whatev(!r of sexual development, the breasts being undeveloped and the pubes liairless. So far as could be ascertained, the thyroid / « A CASK OV Sl'OKADlC CKKriM.SM. Wl'lll KHMAKKS. S^O gland was al)sent, and above tlie clavicles were the peculiar fatty protuberances usually seen in these cases. The circumference of tlie head was twenty-two Indies, and the vertical measurement from the insertion of one ear to the othio', twelve inches. In shape it was brachy- cephalic, with considerable occipital protuberance. The face was flat and broad ; the cheeks hanging and jowl-like, and the eyes set somewhat far apart; the mouth was always partly open, and tlie point of a large smooth Habby tongue visible ; the lips were thick, and the nose flat and ill-formed. The palate was not markedly abnormal, and the tet^tli, though ill-shaped and decayed, were fairly regular. The ears were wing-like and large. The com])lexion was earthy and sallow, and tlie skin could not be pinched up from the subcutaneous tissue. The pulse was eighty-eight, and the temperature normal. The patient could walk, though in a peculiar waddling fashion, and could use l)oth hands. The senses all seemed good, but perception was very slow. The speech was slow and monosyllabic, and indistinct, but she could .say a number of words and tell the names of all ordinary articles about her. She recognised a ]ienny, but called all silver coins without distinction a sliilling ; and though she knew that money would buy sweets, peaches and bananas, had no idea of relative value. She could count up to four only. Could tell her name and age, but no other particulars of her history. She was cleanly in habits, and attentive to the calls of nature, but could not dress herself. She was exceedingly amiable, easily amused, and .strongly imitative. The experience of some months has shown that she is teachable in only a very minor degree. She cannot be got to count above four, but she knows the routine of the establishment, and can tell the hours foi- meals, etc., if asked, and is very appreciative of kindness and fond of those who take notice of and pet her. Altogether, the intellectual development is extremely low in class. Cretinism has been described as characterised by a lesion of the intellectual faculties more or less analogous to that observed in idiocy, and with which is associated a characteristic vicious conformation of the body — an arrest of development of the entirety of the organism. These sjioradic cases certainly conform to this definition, and to any- one who has travelled in the cretinous districts of Switzerland or the Himalayas, or has seen isolated cases of endemic cretinism in French or Italian hospitals for the insane, • the resemblance of the sporadic to the endemic cases is most striking, and is such as to make them recognised at once as belonging to the same family. The more marked physical peculiarities of these cases are the arrest of develop- ment, which seems to occur generally at the period of the first dentition, but in one or two cases has been postponed until the seventh or eighth year, so that at 18 or 20 years of age they are physically children of from 5 to 7 years, and never attain to any sexual development — the peculiar squat conformation, the pallid earthy complexion, the wrinkled skill (especially of the hands), the brachy-cephalic crania, flattentid noses, widely set eyes, thick lips and large flabby tongues, and lastly, the presence of supra-scapular swellings and the absence of the thyroiy marked sun-burning. In spite of tliis, the general aspect, the feel, and a strong suggestion of semi-ti'anslucency in the features, remind one of myxoedema ; but there is no pitting, even on firm pressure. The first set of teeth is persistent, witli the exception of a few that have come out ; those that remain are small, discoloured and worn, the upper incisors particularly being worn down to the level of the gum. The tongue is clean and moist, long and narrow, and tliere is no bad breath. Under- neath the lower jaw there is a soft, pufty, roll-like swelling, presenting the appearance of a " double chin." Girth of neck, 13^- inches. The fulness of the neck makes it impossible to say whether the thyroid is present or not, but there is certainly nothing in the feel of the parts to make one at all confident of its absence. In each supra-clavicular region there is a soft, pufty, obscurely-circumscribed swelling, about the size of half a turkey's eg^, or larger, which feels like fat, but shows no dimpling under the grasp. These, the mother states, were not noticed in the early stages of the disease, and she thinks they are now increasing in size. There is a general diftuse soft pufRness, as of sul)- cutaneous fat, below the clavicles, appai'ently continuous with the supra-clavicular swellings, and extending downwards as far as the areohe, and outwards as far as the anterior border of the axilhe, but not observable in the axillie. Over this area, the superficial veins are conspicuously enlai'ged, especially over the upper j^ai^t. The mamm;e are ill-developed, and tlie nipples are small. The skin of the body is veiy harsh and dry, with a tendency to scaliness, and the mother states that slie never perspires, even under the influence of a steam batli. There is a general puftlness over tlie whole body, but no pitting on pressure in any part of the trunk or limbs. Chast measurement, 29 inches. Respiratory sounds nomnal, and heard clearly o\"er the supra-chivicular swellings. Heart sounds distant, but normal. Pulse 90, normal in cliaracter. The .ibdomen is swollen, prominent, and tynipanitic, with aj'parently nuich subcutaneous fat. Girth at the umbilicus 33J, inches. She is stated to be ^'ery sensitive to the pressure of tightly-fitting clothes. From the percussion sounds, it is po.ssible that the liver mav be enlarged, but the general swelling of the belly A CON'TlilBUTION TO THE STUDY OF SPOUADIC CRETINISM. 84y> makes it ini]iossible to spe;ik with certainty. No hair on the pubes or in the axilhe. The hands are stumpy, broad, purty, and cold, with tlieir skin wrinkled and baggy, as if too large for them. Nails well developed. She is very slow and clumsy in the ust; of her fingers, and finds much difficulty in buttoning lier clothes. 8kin of hands and arms dry and harsh, liaving on the internal surface of tlie latter light In-own patches, composed of aggregations of horny- looking papilhe. The feet are similarly puffy and cold, with the same dry harsh skin as the liands and arms ; on the knees, there are patches of the same horny }>apilla' as were noted on the ai'ms. There is no curving of the tibite, or any bone distortion in any part. The calves ai'e large (11|- inches in girth) and fimn. As she stands stripped, there is a considerable degree of lordosis which, with the large calves, remind one of pseudo- hypertrophic paralysis, but save for extreme sluggishness, there is no difficulty in lising from the recumbent position. 8he walks in an extremely leisurely way, with a waddling gait. In fact, exti-eme fleliberation and sluggishness mark all her actions. Corresponding to the lower cervical and upper dorsal vertebne, there is a diffuse soft, puffy, and elastic swelling, (juite iindefined, but extending over an area of about six inches in diameter, and over tliis surface there is a mai'ked tendency to hairiness, which merges into the hairy scalp at the nape of tlie neck. The appetite is uncertain and capricious ; the bowels regular, but easily upset by irregularities of diet and changes of weather. 3[icturition is frequent. Urine phosphatic, witli trace of albumen. She has never menstruated. The knee-jerk is completely absent, but she is quite sensitive to tickling of the soles. Temperature in the mouth, 97-4°. Tlie special senses appear to be of normal acuteness, save for some weakness of the eyesight at night, probalily due to the palpebral congestion. Her mental faculties may be sunmied up by saying that they are those of a dull child of five, and her mental operations are characterised by the same sluggishness that distinguishes her bodily movements. She can read children's stories, and is fond of being read to. She displays a great want of application, and experiences great difficulty in learning by rote. Her handwriting is neat, but very child- like. In disposition she is amiable but sensitive, and she realises she is not like otiier children. She does not speak much, and when she does, it is in shoi't jerky sentences, ])ut without any trace of ill-temper, and without ejij^ression. She is easily amused, and often laughs in a short spasmodic jerky fashion. Habits perfectly cleanly, and, according to her mother, she " sleejss like a top."' The extremities are always cold and " frog-like," and she is extremely fond of basking in the sun, or in winter before the fire, when slie will sit motionless for hours doing- notliing, al)solutely jilacid, contented and torpid. Case II. E., female, tet. 17] (X(». 4 in the family .series), was a remarkaljiy tine and healthy cliild up to 4 years of age, about which time tlie symptoms as descriljed in the preceding case made their appearance in the same way. At 7 years of age she had diphtheria, but has not had scarlatina. There is a history of some scalp eruption, whicli is described as commencing like a painful boil. There was always the same senitiveness to cold as in tlie preceding case. 844 INTERCOLONIAL MEDICAL CONGRESS OF AUSTllALASIA, Height 3 ft. 1}, in., Aveight 43 lbs., head girth 20i- in., chest girth 23^ in., umbilical girth 2ih in. The general description of the bodily signs of the preceding case apply with almost verbal accuracy to this one also, only it is to be understood that they exist to a less marked ut I see no reference in any of the i^ublished accounts to any occuri'ing elsewhere, so that I may believe that these reports nearly, at any I'ate, exhaust the literature of the subject. The six cases reported above thus form a substantial addition to the number, and, from the unifoi'ndty of the series, should not be without value for future reference. The fourteen cases previously reported are from the following sources : — Mr. Curling, in the "Transactions of the Medico- Chirurgical Society," a"o1. xxxiii, two cases ; Dr. Langdon Down, " Transactions of the Pathological Society," vol. xx, one case ;. Dr. Hilton Fagge, "Trans. Med. Chir. Soc," vol. liv, four cases; and three more in the " Trans. Path. Soc, vol. xxv, where there is also a case reported by Mr. Fletcher Beach; Dr. Ilouth, "Proceedings of the Medical Society," vol. vii, one case ; Dr. Sidney Phillips, " Clinical Society's Trans- actions," vol. xviii, one case ; Dr. H. H. Robinson, " Clin. Soc. Trans.," vol. XX, one case. On reference to tlie aboxe cases and those now brought forward, it will be seen that, in spite of some differences, there is such a close generic resemblance between them, as to make it evident that all were of the same nature. The general characters of the aliection need not be repeated here, as they have been well summed up Ijy Dr. Fagge in the paper before referred to, and again appeal- in the detailed account of the first case of the present series. The interest of the aU'ection lies of course in its causation, for whicli we are yet without a satisfactory theory, as well as in the exact natui'e of the changes in the organs and tissues, on which point the evidence is extremely scanty. Indeed, so far, the only substantial and constant pathological fact, is the proof of the fatty nature of the supra-clavicular tumours, ANhich it will l)e seen existed at some time or other in every one of the recorded cases. The interest of the whole subject is further increased by the evident similai-ity of many of the symptoms to those of myxoedema, a point which has been noted by previous writer.s, and "which is so well-marked in the present series. 848 IXTERCOLOMAL MEDICAL CONGRESS OF AUSTRALASIA. * The question of the rehitionship of the thyroid to niyxoedematou.s changes cannot be entered into here, but tlie proved absence of Una organ in the two first cases of sporadic cretinism examined, and its putative absence in several others of the living cases, could not fail to suggest the theory enunciated by Dr. Fagge, that the absence of the thyroid was the prime cause of this affection. However, the proved presence of a thyroid of considerable size in a subsequent case, caused Dr. Fagge himself to recognise that other causes must be looked for. In the light of subsequent events, it is of course to be regretted that no micioscopic examination of the thyroid in this case was made. The theory of Dr. Langdon Down, that the mental and bodily stunting results from the intoxication of one or both parents at tlie time of procreation, finds no support in any of my cases, or in any others except his own, that I can see. There were no instrumental deliveries in any of my cases, a theory which was at one time urged, in reference to the endemic form of cretinism, and suggested as a possible cause of the sporadic form ; nor do they lend any additional support to the idea, that fright during pregnancy might have something to do with the origin of the affection, though, as pointed out by Dr. Sidney Phillips, this has actually occurred in three instances. Nothing apparently can l)e attributed to consanguinity, or to any kind of local influence. The principal features of the first five of the series which I present, are undoubtedly the comparatively large number of tlie same family who were affected, and in all the remarkable uniformity of the age at which the cretinoid symptoms commenced, viz., at about three years of age. Having in the first place learned these two facts, I was in great hopes that such favourable circiunstances would permit a careful investigation to throw some additional light on the question of the origin ; but in this I have not been successful, as I can detect nothing which in any way distinguishes the birth, early growth, or rearing of the affected, fi'om the healthy members. This uniformity of the time of onset does not exist in the English cases. Taking the cases in which the period is definitely stated, I find that in one the symptoms were congenital, in four they supervened at 1, 2^, 7 and 8 years respectively ; in another, the child was noticed to become less active at 9 months, and to cease growing at 2^ to 3 years. In thi-ee of Dr. Fagge's cases there was evidently some bodily change, which was probably the beginning of the affection in question at 6, 5 and 8 months respectively. In Dr. Robinson's case, the child is reported as being weakly from birth, and not walking until 12 years of age, or speaking until 13. Still, in spite of these variations, the age of about three years stands out as being the most favoured epoch for the onset. There is another point to which the South Australian cases suggest a reference, viz., the numerical size of the families in which sporadic cretinism has occurred. The two families in which my cases were found were large, being eleven and ten in number respectively. In two other instances, the families consisted of seven membei-s ; and in each of two more, they were five in number. Of the sex, six only of the twenty cases now recorded have been males, and fourteen females, showing, as far as tlie figures go, an increased liability to the affection on the pai't of female childrea. RACE AND INSAXITV IX XEW SOUTH WALKS. 849 Witli regard to the possible existejice cand influence of any hereditary disease, the only noteworthy features are the existence of epilepsy in two of the affected families, and a severe taint of phthisis in another. No bone deformity, nor evidence of a past or present rachitic state, existed in any of my cases, though this has been observed by others ; nor does there appear to be the slightest evidence to connect the affection with syphilis. The fontanelles which are reported to have been open in thi'ee previous cases, were open m one only of mine (No. 6), and in no case did I observe any abnormality in the shape of the skull, such as has been occasionally, but rarely, noticed. The measurements which are given in my own series, show a fair sized head in each case. There is one symptom which was a conspicuous element in all my cases, which I do not find specially mentioned in any of the others. I allude to the marked tumefaction, with tendency to hairines.s, over the region of the lower cervical and upper dorsal vertebra?. It may be, however, that Mr. Curling's statement, that the " dorsal svirface of the body .... was hairy," is an indication that this symptom may liave existed in one of his cases. Reading this symptom by the light of the general tumefaction in other parts, and the proved existence of fat in the supra-clavicular regions, we may surmise that these dorsal swellings are also fat. If that be the case, it brings forward the abnormal development of fat as a marked feature of the affection. From the preceding remarks, it will be seen that I am unable to >7»'>-inT' ^ puB IfuBuriag :d o -ri CO '^ 00 ^ OS CI o H^ w . ojf^or't^^ coT* • ■ --< ^ - • •-' Ah «-" CO "-^ O • GO ^ OS t^ CO • • fH • • I— 1 nH rH CO c: ip^oog ^^ ^ « ^ r^ s f2 c, s rH Ah Ol l.~ OJ ? O) ?! C-. iP C. 9 -H 00 CO r . -rH 04 ^^ C^ CO CO o r^ liO -* O ^ ^ '"'00 - - - " ' rH 1— 1 OJ M o o -qsu] O o .* O0-JCO-t(rH O'*' ^O CO^ rH'^CO-**'tO'-(»^(M?C0?5.^Q0.^:O C^o — c-i -^tc CO^jrHrnCOoo'^-OOWcO OrH'^H^ CO States of Mental Exaltation, v including — (<') Mania, Acute ib) ,, Sub-acute . . *- ((•) ., Senile (<0 „ Puei^peral (<■) ,, Recurrent . . > States of Mental Depression, 'j including — («) Simjile Melancholia . . - (^/) Acute (c) Puerperal ,, .. j States of Mental Enfeeble- \ ment, including— ('0 Primary Dementia . . 1 (6) Secondary ,, . . T (e) Organic (<0 Paralytic ,, ..] Epileptic Insanity General Paralysis jParanoia, or Delusional \ \ Insanity .. ) General Insanity, including) Chronic Jlania .. > Mania I i Melancholia e potu \ Dementia ) ( Hysterical Insai ity .. Imbecility .. Idiocy j Total of each Nationality INSANITY IN AUSTRALIAN ABORIGINES. 857 Table IL Shoioing average members of respective nationalities resident in ^^.S.W. during 1878-1887. 1 2 3 4 5 (5 7 8 !) 10 11 Nationalities. Australasian English . . Irish Scotcli Chinese . . Germans, etc. Welsli Scandinavians, &c. U.S. America, &c. French, &c. All other Nations Population. 509,788 10('),20O (;<.), 044 24,828 10,179 7,809 3,067 2,958 2,407 1,369 110,076 Total 847,725 Table III. Showing 2^''oportion of iiisane of each nationalitg in Gladesville to persons of that nationality resident in X.S.W. during 1878-1887. Nationalities. Insanity According to Population. 1 French 1 in every 76 2 Germans, &c. 85 3 Scandinavians, &c. 89 4 Irish 93 5 U.S. America, &c. 96 6 Welsh „ 127 7 English . . „ 135 8 Scotch „ 1.55 9 Chinese . , „ 188 10 Australasian „ 579 INSANITY IN AUSTRALIAN ABOllIGINES, WITH A BRIEF ANALYSIS OF THIRTY-TWO CASES. By F. Norton Manning, M.D. Inspector-General of the Insane in New South Wales, and Lecturer on Psychological Medicine in tlie University of Sydney. So far a.s can be gathered from tlie accounts published by explorers and early colonists, insanity was a very rare aliection among the Australian aborigines whilst in their primitive and uncivilised condition.* From such accounts as are accessible, it appears that when insanity did occur, if the subject of it was violent and aggressive, • "The Australian Kace," by Edward M. Curr, p. 2'J3. 858 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. he was promptly slauglitered ;* if melancliolic, he was allowed — if so disposed — to commit suicide ; if demented and helpless, he was left to die ; and only when quiet and peaceable, and when his erroneous ideas did not result in offensive acts, was he allowed to continue in the trilje, and in some cases was held in reverence as a superior and inspired being. The Australian aborigines, in fact, acted towards their insane in much the same manner as almost all savage races apjDear to have done, and carried out to its fullest extent, in this respect, the great principle of the survival of the fittest — practically working in the direction of stamping out tlie malady. In addition to this, their simple and uneventful existence, without worry or strain, and their marriage laws (which forbade all consanguineous, or even intertribal or interseptal marriages) served to prevent the occurrence of what may be called occasional, and of hereditary insanity. As time rolled on, and the aborigines were brought more in contact with Europeans, and became acquainted with the vices and the cai*e» of civilisation, we find more frequent notices of mental disease. The Rev. George Taphill writing on " The Natives of New South Wales," says : — " I have frequently seen cases of epilepsy " (p. 259). " I have seen several cases of lunacy among them, and it is not uncommon for the intellect of old men to give way, and for them to be insane " (p. 260). Mr. Phillip Clancy, in an appendix to Mr. Brough Smyth's learned work on " The Australian Aborigines," says : — " I have never observed insanity or hereditary or chronic complaints among the natives, except in those vitiated by white people " (p. 254) ; and Mr. James Dawson writes : — " Suicide is uncommon and cases of insanity rarely met with, but the aborigines believe there is more of it since the use of intoxicating liquors, and especially since they began to disregard their laws of consanguinity in marriage" (pp. 61 and 62). The growing amount of insanity, and the greater tendency to it in so-called civilised aboi'igines, are illustrated by the statistics of Queensland and New South Wales. In Queensland a large part of the aboriginal population had not, until quite recent years, been brouglit into contact with more than the confines of civilisation. This population is estimated, as I gather from information obtained from the Registrar-General's Office in Brisbane, at something like 20,000, whilst the number of aljorigines admitted to Queensland asylums, since the year 1868, has been fourteen only. The aboriginal poj^ulation of New South Wales has been for years past a miserable remnant, supported for the most part by the Government, afflicted with the vices and diseases of civilisation, and devoid of the nobler and better chai-acteristics of the race. Since the year 1868, 18 aborigines have been admitted to the asylums of New South Wales from a population which has never during that time exceeded 2500, and is now less than half that number. It is noteworthy too, that during tlie decennial period 1868-1877, eight aborigines were admitted ; wliilst during the next decade 1878-1887, ten wei'e received, showing an increasing number of insane, whilst the aboriginal population was steadily decreasing. In the census year 1881, the proportion of aboriginal insane to the aboriginal population in New South Wales was 2"8;3 per thousand, a proportion in excess of that for the general * " Aus-traliau Aborigines," by James Dawson, yt. 01. INSANITV IX AUSTHALIAX AUOHIGINES. 859' jiopuliition : and at tlic clo.so of I.'^N?, it was upwards of 5 per thousand. The rate at this period would liave been even higher, if the duration of life in aborigines in conHncnient were not extremely sliort, and much below the average of tliat of Europeans under similar conditions. We have then, in New South Wales, passed from a period in which insanity was ahnost unknown among the native race, to one in which it is almost twice as conunon as among the European race inhabiting the same territory. I liave received from my friend and colleague Dr. Scholes, brief notes of all the cases (foui'teen in number) admitted to Queensland asylums since 1868 ; and all admitted to asylums in Xew South Wales, fi'om August 1, 1868, to December 31, 1887, (eighteen in numl)ei-), came more or less fully under my own observation. Of the thirty-two cases, twenty-foui' were males and eight females, and the following short return gi\es the general results : — JIale.-.. Females. Total. Admitted ... ... 24 8 3-2 Died 17 :] 20 Dischai;ged recovered 3 3 6 Remaining ... 4 2 6 In addition to the above, two half-castes were admitted. In considering the causation of the malady in these thirty-two cases,, it was beyond a doubt that the chief share was due to civilisation and. its accompanying vices, and to the changes of life and habits incident to this. A considerable propoi'tion of the cases were due directly to drink ; four or five were due to impi'isonment, awarded either for offences springing from drink, or for violence which, though witliin the ethical code of the nati\e, was by civilisation accounted a crime. It was a remarkable fact that, with one or two exceptions, the whole of the patients spoke English — some witli great facility and correctness, and with a rich knowledge of expletive and objurgatoiy expression. Three of the patients had served in the [)olice as troopers or trackers. As might have been expected in a dai-k -skinned race, the prevailing type of the malady was mania, usually acute, and as a rule accom- jmnied by turbulence and violence, and this passed very rapidly — much more rapidly than in Europeans — into dementia, with filthy and degraded habits. In some of the cases, the hallucinations of sight and hearing were extremely vivid ; and in one of the less civilised cases, the patient, not I'ecognising his own reflection, persistently smashed looking-glasses, or tore them down when in fixed positions, .so as to get at the source of the voices which annoyed him. The melancholic ca.ses all originated in gaol, and were due apparently to more or less prolonged imprisonment for ort'ences sucli as rape, wife murder, or manslaughter, wliich the native code regarded as venial. The melancholic as well as the maniacal cases tended at an early stage to dementia, and this was in most cases extreme, and accomiianied by failing health and indescribably dirty liabits. Epilepsy occurred in three cases, and the fits were well marked and severe. No ca.se of general paralysis, or anything which could be mistaken for it was seen, and there were no cases of monomania or delusional insanity. 860 INTEKCOLONIAL MEDICAL CONGRKSS OF AUSTHALASIA. One of Dr. Sclioles' cases was an imbecile, but as the girl was blind from a very early age, it was difficulty to say whether the imbecility was congenital, or was mainly due to deprivation. Another of Dr. Scholes' cases was an excellent example of puerperal mania. It followed imme- diately on the birth of the patient's second child, and she was admitted ■a foi'tnight after parturition, the breasts being full of milk, and all the ordinary symptoms of puerperal mania present. She made a good, but not rapid, recovery. The cases of recovery — six only in number — were in hospital for comparatively sliort jieriods, the longest being eight months. In several cases discharge was postponed, owing to the difficulty of fixing a standard of saneness, and also by reason of the necessity of finding a home for the patient. In only one case was there relapse and re-admission, and in this, the cause of the original attack and of the relapse was drink. The deaths numbered twenty, and in several cases the only cause Avhich could be assigned was " marasmus " — a gradual wasting, without tubercular or other manifest ailment. Eight deaths were due to phthisis, either comparatively slow in approach, or in the form of rapid tuberculosis. Two died from epilepsy, three from serous apoplexy, ^nd one from maniacal exhaustion. Tlie average duration of life in hospital was much shorter than in Europeans. The confinement, though tempered by many unaccus- tomed comforts, being apparently the great factor in shortening life. Two of the men were described as the last of their tribes. Several of the women were much cut about the head, in accordance with Aboriginal custom. In one case, the cuts penetrated the outer table of the skull, which now forms an admirable museum specimen, in several places. All the cases now in hospital display considerable dementia, but two are usefully employed. INEBRIETY— ITS ETIOLOGY AND TREATMENT. By Patrick Smith, M.D. What is inebriety ? Inebriety may be defined to be an overwhelming morbid desire for the state of intoxication, or narcotism. I say advisedly intoxication, in contra-distinction to intoxicating liquors. This definition at once excludes the great majority of so-called drinkers or drunkards, for some drink out of good-fellowship, others for the exhilarating effects to be obtained, and a few for the pleasurable sensations to the palate. But it is the aim and object of most to stop short of intoxication. If drinking were likely to affect their position, socially or pecuni.irily, oi- to interfere with their health, comfort, or convenience, the liabit could be given up with greater or less effort by all. In sliort, they are not yet under the power- of the habit. Now in so far as such do injury to themselves, or are entrapped by intoxication, they must be classified as vicious. This is the vice of inebriety. It is INEUIUKTV ITS KTIOLOfJY AND TliEATMKXT. 861 fi'om the niuks of the vicious driukei's tliat the inebriates, strictly so called, are drawn. A careless habit or social custom has been followed till it has become a vice, which in time may develope into a disease. T shall confine my attention in this paper, not to the vicious inebriate, but to the diseased. The inei)riate propei' is a remarkable contrast to the di'unkard. He cannot drink in moderation. For him, no apprenticeship of years, or lon<^ familiarity with alcohol is necessai'y. On slight acquaiiitance, a tierce ungovernaljle desire is set up. Two men begin to drink together, say from the same l)ottle, and after one or two glasses, one is totally unattected, bilt^in the other a craving has been excited, wdiich only a complete debauch will satisfy. Loss of position, of character, of fortune, and of health may be the I'esult of the gratification of this impulse, but tliese are utterly disregarded. Dr. Wright, in his work on " Inebrietism," page 43, thus describes and explains tiiis craving : — " The whole mind is lilled, at certain times, with the contemplation of an imperative morbid desire. All the resources possible ax-e brouglit to bear in pro- curing the gratification of a per\ading and domineei'ing appetite. Such a condition of perverted inclination will i-est content with nothing short of the con^plete satisfaction of its demands. Any such satisfaction must reflect properties e([ually powerful and unixersal with the element demanding it, and also equally morbid." The question arises — Why was the one drinker uninfluenced by the same quantity of the same liquor, and why in the other Avas there such a tempest of desire aroused 1 Was the one totally depraved, or less under the resti-aining power of religious, moral, or social influences than the other? The probability is that such was not the case. The coii- clusion is ine\'itable, that the difference in effects arose from a fundamental difference in constitution. In the one case, there was no response to the stimulant from without, wdiile in the other the response was totally disproportionate. The one had not what is technically called the neurotic tempei'ament or diathesis, while the other had. What is the neurotic temjierament ? In this temperament, when it is a damnosa liereditas, tliere is some fundamental deficiency, lesion, or flaw of the brain, whereby that organ is placed in a state of unstable eciuilibrium. To borrow a term from meclianics — the governor of the engine is faulty. There is an extreme susceptibility in the nervous sy.stem to take no spasmodic action. A stimulus applied from without, which in the healthy would be without effect, creates in the neurotic subject an outburst, or quasi-storm of function, which has been described as beyond his control, and without his consent. The power of inhibition and of will are for the time lost. Handicapped with such a tempera- ment, the neurotic is indeed an object for pity. How is such an one to meet the trials and temptations of life without succumbing to them 1 Only by the most judicious management and intimate knowledge of his condition. Maudsley says that this neurotic or spismodic temperament is fundamental— its outcomes, various. It will be a mere accident, depending on external influences, whether this diathesis will lead its po.s.sessor to ci'ime, inebriety, or insanity. However, it is just possible it may remain latent through life. If search be made into the family history of the neui^otic, very decided confirmation of the law of heredity 562 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. may be discovered. Tt is found, except in the rarest instances, either that one or both of his paroits, or grandparents — not to go further back — had a strain of insanity, or inebriety, or crime in their con- stitution ; or that they suti'ered from epilepsy, or some wasting disease ; or that they were deljilitated, from overstrain of mental work, oi- excesses of some kind ; or were themselves neurotic. The neurotic diathesis, though usually inherited, may also be acquired. The high state of nervous tension, which has been induced by our modern civilisation, tlie hurry, bustle, and excitement in which we live, the temptation to engage in speculation, which involves risk and anxiety ; the injury done to the young in the tierce competition of school life, the prevalence of luxurious and drinking habits, and the debilitating influences brought to bear in coneeiitrated form on our own generation, as on no foi'mer one, tend to make neurotic parents, in wliose ottspring the diathesis must appear in a still more marked form. The increase of neurotics at the present time is in the light of these conditions easily comprehended. Now, all that applies to the general neui'otic condition, applies equally to the special neurosis of inebriety — the alcoholic. Some are born with a special susceptibility to the stimulus of alcohol, and an insignificant quantity drunk produce in such the most disproportionate results — the morbid craving before described. It is in this brain deficiency, inherited or acquired by long indulgence in alcoholic liquors, that we have the fons et origo of the craving for narcotism. The act of drunkenness is merely the expression of the inward craving, just as the ■excessive drinking of Avater is the expression of the existence of a feverisli or other diseased condition. The symptoms haAe attracted the ■chief attention, while the real disease has been unnoticed. It is surely then a legitimate deduction, that a craving so fierce, so disjDropoi'tionate to the exciting cause, is not due to the gratification of the palate, but to a diseased condition. That craving must surely be due to disease, which suddenly seizes on some of the most cultured, refined, and generous men, which in a few hours completely changes their characters, and causes them to associate with men they despise, and makes them resort to cruelty, and selfishness, and meanness, utterly foreign to their nature. The close analogy existing between insanity and ineljriety proves tlie existence of an alcoholic, as well as of an insane, neurosis. The funda- mental principle on which insanity is treated, is that it is a physical disease. As we are warranted in inferring a morbid diathesis in the one case, so are we in the other. 80 alike in almost eveiy respect are tlie symptoms of periodic insanity and of dipsomania, that apart fron the history of the case, it would be hard to distinguish between them. In both the attack may come without any known exciting cause ; for it is not always necessary to take alcohol to set w.]) an attack. On the contrary, the impulse is from within — central. The attack once begun rapidly advances to an explosive point. If alcohol be obtainable, the impulse cannot be stayed till conqjlete exhaustion of mind and body is reached. When the point of narcotism is readied the craving ceases, and an interval of comparative qviiet succeeds, during wliich the dipso- maniac has no inclination foi* alcohol, and may even loathe it. Another attack, exactly like tlie foi'mer, at irregular intervals of weeks, or INEBRIETY ITS ETIOLOGY AND TREATMENT. 863 perliJips inontlis, follows, and it is this periodicity that stamps the attack as a neurosis. The prodroniic symptoms in both cases are exactly alike. In both, there may be observed a day or two prior to an attack, some alteration in manner, gait, oi* speech, a twitching of the muscles of the face or fingers, or a general restlessness and malaise. But a craving, similar in degree and nature, may also be acquired by the habitual drinker. The periodicity of the attack in his case is absent, but craving may be said to be perpetual. In the former it would surely be monstrous to impute vice, whereas in the latter no condemnation can be strong enough. Injuries to the liead, and the conseipu'ut disease of some portion of the brain, are a frequent cause of sudden development of inebriety, just as of insanity. After an injury to the head, a considerable interval may elapse before inebriety shows itself, because time is required for the morbid changes set up to extend far enough to produce a condition of unstable equilibrium. Disease origin is doubly proved in such cases, for when the injury is capable of repair by surgical means, the inebriety <;ea.ses. Out of 600 inebriates treated at Fort Hamilton (the Inebriate Ketreat for the State of Xew York), Dr. Norman Kerr tells us (" Inebriety," page 165) that 123, oi- nearly one-hfth, had received blows on the head ; one-third of these were fractures of the skvill. Out of the 123, seventy-oiie had become habitual, and tifty-two periodic, ineln-iates. In the Dalrymple Home at Bickmanswarth, England, out of 103 admissions, six owed their inebriety to injuries of some kind, three being in the region of the head. When we hnd outbreaks of inebriety, just as of insanity, following more or less closely, even in previously sober people, on heat apoplexy, on severe nervous shocks from excessive grief, or from railway or other accidents, in the course of wasting diseases, in nervous exhaustion, it seems impossible not to admit a physical disease origin. With regai'd to the crucial test of jjost-mortem appearances, inebi'iety like insanity being to a large extent functional, and due to congenital or prenatal brain deficiency, morbid clianges cannot in the present state of our chemical and mechanical knowledge be demonstrated. When the disease is of long standing, especially if acquired by long- continued hard drinking, alterations in the encephalon structures are found, but these are the results, not the causes, of disease. Dr. N". Kerr (" Inebriety," p. 212) says : — "That in his examination of the bodies of those who died during, or immediately after an attack of inebriety, he found appearances of hypera-mia, injection of the mucous membrane of the stomach — in cases so inflamed as to suggest metallic poisoning ; in all cases, congestion of the meninges ; in several, general congestion of the brain ; and extravasations of blood existed both on the interior and exterior of the cerebrum." More extended observation will no doubt add to our knowledge of these morbid appearances, which are after all only what might be expected fi-om the symptoms. Assuming then, that inebriety is a physical disease, I proceed to inquire what we can reasonably expect to accomplish by treatment. Up to within a very recent pei-iod, inebriety has been regarded by the profession and the public as arising from utter moral depravity, and as such to be dealt with by clergymen, social reformers, and temperance lecturei-s. But thanks to our professional brethren in America, who 864 INTERCOLOXIAL MEDICAL COXGRESS OF AUSTRALASIA. ]la^'e nobly pioneered this field of study, it is widely recognised as a physical disease and amenable to treatment. As a profession, we regarded the inebriate with despair, but now we ai^e more hopeful. Moral and religious influences and persuasion have induced multitudes to reform, and have saved them from becoming dipsomaniacs ; but the diseased inebriate and the dipsomaniac has been proof against all attempts to reform. But, what is possible to be done by treatment ? We cannot eradicate the diathesis, and give the inebriate a new constitution ; but we can recognise the symptoms of a coming attack, and prepare for it. The pi'odromata, the restlessness, depi'ession, timidity, the muscular twitching and other storm signals alx'eady mentioned, can be corrected and rendered practically harmless. Especially can we attend to organs which may be in a morbid condition by medicinal and hygienic appliances. We can promote the repair of diseased tissue, and with healthy oi'gans may expect to remove morljid craving. Two conditions, and only two, are essential to the attainment of cure as far as that may be possible, viz., the withdrawal of alcohol from the inebriate, and securing suflicient time for the repair of damage done to organs and tissues. Easy as these two conditions seem, they are even now most difficult of attainment. Home treatment of the inebriate on many accounts so desirable, is rendered all but hopeless, on account of the difficulty of preventing the patient from obtaining liquor ; let those testify, who have ever made the attempt. Is it any wonder that failure has been the result? Even Inebriate Asylums in America and elsewhere, have largely failed on account of not being able to overcome this difficulty. Prior to the establishment of retreats, it was only in gaols and lunatic asylums that alcohol could be efi'ectively prohibited ; but they failed, and still fail to cure, because sufficient time for the repair of diseased tissue cannot be obtained ; not even the most worthless police-court " repeater," let alone a wage-earning citizen, Avould be sent to gaol for a year for drunkenness ; nor even the worst dipsomaniac is it now possible to keep for a like period in a lunatic asylum. For as soon as the attack is over, the detained can plead so well his possession of all his faculties, his loss of time, his surroundings, that .speedy release generally follows ; thus sufficient time is not allowed. The shortest time of treatment which would give even the hope of permanent cure, is allowed to be a year. Dx\ W. B. Richardson gives it as his estimate, that two years are required for many, and that three, four, or even five years for numbers. What can moral and religious influences do against a disease so formidable ? The great obstacle to efficient cure in insanity, with all our enlightenment on the subject, is the element of time. If it has taken so long to impress the public mind with the essential nature of the time element in a disease so plainly marked as insanity, what can be expected in inebriety, which even now, many refuse to recognise as a disease. While on the subject of treatment of inebriates in lunatic asylums, I state, on the authority of Dr. Norman Kerr ("Inebriety"), that an attempt is being made to treat inebriates in lunatic asylums in New Zealand. They are kept in separate wards, and do not mingle with the insane. Tlie combination has very much to recommend it. There is no need to agitate and wait for the erection of retreats, as the INEBRIETY—ITS ETIOLOGY AND TREATMENT. 865 asylums arc accessible to e\evy part of tlic country. There is only one ol)jection that I can see to this combination — but that is likely to militate very strongly against voluntary seclusion — and that is, that the attainder of insanity is likely to attach to inebriates who have been treated in lunatic asylums. The experiment will be watched with great interest. But to return, the only chance of securing eftectually the two conditions referred to, seems to be to place the inebriate in a home or retreat. Here he would be relie\ed from the upbraidings and i-eproaches of relatives who, belio\ing that it is only want of will that stands between him and cure, cannot keep from aggravating and annoying. In a retreat, too, it ought to be possible to bring to bear on the inebriate all the resources of medicine and hygiene, and so greatly expedite the process of repair and the restoration of healthy function. It would be presumptuous in me to enter into details of treatment, even did time allow. It is of the last importance, if restoration is to be accomplished, that the co-operation of the patient himself should be obtained. " \Mio would be free, himself must strike the blow," is very pertinent to the case of the inebriate. If there be no strong desire for cure on the part of the patient, then indeed is the case a desperate one. But fortunately, this desire is seldom absent. It is necessary by little — and little it may be — but it is necessary that the patient be fully informed of the grave disease of which he is the subject. He should know his family history — the failing, or vices, or diseases of his immediate ancestry ; the necessity, if ever he is again successfully to face the temptations and troubles of life, of obtaining a radical cure. Above all, he should be taught to recognise the physical and mental conditions that hei'ald an attack of the craving. Nor are the aids of religion and morality, though in themselves impotent to suddenly bring about a cure of a diseased condition, to be despised. Those who believe in the possibility of Divine aid being extended to the distressed, may by prayer be greatly strengthened in their attempts at refoiination. If the physical state of the inebriate is such as I have described, the utter uselessness of antidotes for the drink-craving, and of the belauded specifics, must be at once apparent. The Turkish bath, cinchona rubra, raw-meat diet, all valuable as adjuncts to treatment, are in tliemselves valueless, as experience has well pro^"ed. In Victoria, South Australia and New Zealand, tlie laws give ample opportunity to deal with inel:)riates, either by Aoluntary or compulsory seclusion in asylums or I'etreats. In New South Wales and Queensland similar legislation is promised. It is only a few months since a similar law was placed in the English Statute-book. Legislation then is fairly abreast, if not ahead, of public opinion. Bnt there is much necessity for the education of public opinion on this subject. There are many inebriates in the colonies where reti'eats have been by law established, but how few seem anxious to avail themsehes of tliem. We must recognise that most inheritors of the alcoholic diathesis are ignorant of the fact. Many have a dim idea that their indulgence in drink is moie than a craving — that it is a disease ; but e\en so, it is a disease for which there is no cure. 2k 866 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. As a profession, it is only within a few years back that we have given in our adhesion to the disease oiigin of the drink craving, if some are not even now avowed sceptics ; and if so, what can we expect in the general public? If inebriates are to he effectually helped, it can only be liy pulilic opinion being enlightened on the subject. The press is doubtless the best educator of public opinion. In England and America, there are established societies for the study of inebriety. Similar societies might well be tried here. Just as our Health Societies popularise the laws of health, so might such societies popularise the laws of inebriety. Whatever means we employ, efforts ought to be made to extend to the inebriate — than whom none more deserves our pity — a helping hand. We should do our duty by the inebriate, as we have already done by those afflicted with a similar malady — the insane. Provision should be made for rich and poor alike in asylums or retreats. I am not referring — in naming asylums or retreats as the only satisfactory mode of treatment — to the ordinary drunkard or tippler, for if so, then no number of institutions that we could erect would be sufficient to contain them. The provision for the true inebriate, whether rich or pooi", would no doubt entail considerable outlay ; and yet, not so. much as might at first sight appear. For a large number of the police-court drunkards — a proportion of whom are, no doubt, diseased — are already a public burden, for Avhen not in gaol, they live on private charity. They cost the country more than if they were systematically maintained by it. A sufficiently long period of detention, during which they might be compelled to work, might effect a cure. Coming to the skilled mechanic or ordinary wage-earning inebriate, the labour that could be done by such while in seclusion might amount to little short of maintaining him. A certain proportion of inebriates, socially higher than those mentioned, might he paid for by friends to the full, so that the expense of main- tenance would be small in comparison to the good effected directly, and tlie indirect gain would be even greater. But into details of such a scheme, it is impossible here to enter. But it may be asked — What are the actual results from the establish- ment of retreats ? The movement for the rescue of the inebriate is only of yesterday, and statistics cannot be other than meagre as yet. Dr. T. D. Crothers of America, at the Colonial and International Congress on Inebriety held in London last year, stated that out of 3000 cases of inebriety ti'eated in American institutions, nearly forty per cent, were restored and temperate after a period of from six to eight years from the time of their discharge. The results of treatment at the Dalrymple Home in England are given as 42 per cent, of recoveries, out of a total of eighty-two under treatment. A percentage of 35 of permanent cures is considered a fair general average in the case of those who remain under treatment for one year. There is a very close approximation to the general average of cures among the insane. These results are, considering the difficulties attending the inception of a new system, eminently satisfactory. Our great hope in coping with this formidable ailment, which threatens to sap tlie physique of our own generation specially, is in the diffusion of a more accurate knowledge of the effects of alcohol on the system. The ignorance that prevails on this point in the popular A CO\THIHUTIO\ TO THK STUDY OK IXlCBinETV. 867 mind is simply inci-edible. Were the disease-producing qualities of alcohol better understood, many now on the high road to inebriety would recognise their own symptoms, at a stage when they were curable. ^Many who are advanced in disease would submit themsehes to curative means. We miglit almost despair of ever sufficiently educating pul)lic opinion on inebriety, liad we not before us the history of the long battle that had to be fought ere due provision was made foi- the sciei:(,titic treatment of insanity. The propositions which T have very briefly and vny imperfectly tried to establish are these : — That the inordinate craving for intoxication, which is irresistible, has its /otts et orlyo in the alcoliolic diathesis or temperament, a subdivision of the neurotic group of diatheses; that intoxication is merely a symptom or outward expression of an internal morbid state, and is not itself the disease ; that the originating causes of inebriety are so analogous to those of insanity, as to warrant the inference that, if the one is a physical disease, so is the other ; that the essential conditions of successful treatment are two — viz., the absolute prohibition to the patient of alcohol, and the granting of sufficient time for tlie reparation of diseased tissue and restoration of lost func- tion ; and that asylums or reti-eats afford the best means of securin" the fulfilment of these conditions. The paper was well received, and all were agreed that treatment, to be successful, must carry with it the co-operation of the patient, and that treatment away from home was absolutely necessary. The associa- tion of inebriates and the insane was strongly decried, a separate institution being clearly I'equisite. It was approved that the law should allow some authority, such as a judge or justice, on proof being shown to commit the patient for treatment ; and that treatment, to be effective, .shoidd be for at least one year. Dr: Patrick Smith briefly replied. A CO^^TRIBUTIOX TO THE STUDY OF INEBRIETY. By CiiAKLEs McCarthy, ^[.D., Inebriate Ketreat, Northcote, ^Eelbourne. Hon. Member, American Association for Cure of Inebriates. Hon. Member, Council of the Society for the Study and Care of Inebriety in England. As to statistics of cure, they are valueless unless based on large numbei-s in inebriety, where the puVjlic demand a new definition of cure, namely, its permanency. The inelniate has such a craving for stimulants or narcotics, lirc, that if not under restraint, he cannot refrain from over indulgence; the drunkard can, if he choose. The inebriate is suffering from disease of the nervous system — he is labouring under moral insanity. There is no inebriety in a medical sense witliout disease of the brain, either functional or structural. The 2k 2 868 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. man may appear to reason well, l:>ut though his language may be sane,, his conduct is insane. Generally speaking, no exhortation, no con- sideration (temporal or spiritual), no ruin staring him in the face, nO' affection for family will weigh with him; indulge he must, and Avill, until he becomes helpless. Consequences are nothing to Tiim before indulgence, and everything after; then his i-emorse imposes on his friends, who determine to give him another trial. But, alas ! the f)aroxysms and the scenes are repeated until he dies, or becomes insane. To say that this state dejaends on vice, betrays extreme ignorance. It may have been so at first, l)ut it is disease now. What are the causes of inebriety ? They are numerous. The most frequent cause is indulgence in alcohol acting on a constitution predis- fjosed to nervous disease; were it not for this predisposition, tlie person's excessive indulgence may terminate in lunacy or death, without his becoming an inebriate. Next to this, and nearly allied to it, but much more difficult to cure, are hereditary cases, which are very frequently periodical. This heredity may be from parents or grandparents, or from more remote sources. There is nothing strange in this. I have often called the attention of parents to the fact that the new-born babe did not resemble either of them, when I was informed that it resembled an uncle or an aunt, or more distant relative. It is quite certain that all children inherit some taint or peculiarity of their parents or relatives — some children one thing, some another. When the father and mother are both drunkards before the child's conception, there is great proba- bility that the child's nature will be degraded, so that it may be born an idiot ; or, when grown up, become imbecile, consumptive, an inebriate, a drunkard, or a criminal, the source of whose misfortune is never dreamed of. Many of this class inhabit the jails, the lunatic asylums, or end their lives on the gallows. It is not outside this consideration to state that the neglect of early religious and moi'al training and education will very materially tend to insure and accelerate the degi-adation necessarily resulting from heredity and over-indulgence, and at the saiiie time certainly impede, if not hinder, the cure of inebriates. I think it very improbable that an inebriate who does not believe in a future judgement, can be cured, as he has n® motive strong enough to induce him to have recourse to any self-denial, which is certainly necessary as an adjuvant in effecting permanent cure. This is no contradiction of the A-iew, that inebriety is a disease, as our lunacy doctors Avell know and utilise in practice. This question of heredity as to drink, profligacy, lunacy, ignorance, indulgence, and all inherited unhealthy states and diseases, is a question of the utmost importance, and should engage the serious consideration of legislators, and of all those who wish well to posterity. This is of more importance than the interest of the liquor trade. As inebriety is a frequent cause of insanity, so may it also be a symptom of insanity. Sunsti'oke, shock, grief, melancholy, remorse, debilitating diseases, injury to the brain, in fact any cause that may produce insanity, may l)e the cause of inebriety. A sound mind requires a sound brain and healthy body ; yes, and healthy ancestors, those who have marriageable sons or daughters, should not forget this. I need say no more, nor perhaps so mucli, to a medical audience, but others may profit by these warning remarks, which are free of all technicalities. A COXTHIIJUTION TO I III:; STUDY OF IXEHUIKTY. 869 What is to be done about inebriety? Let the medical profession insist upon the establishment of inebriate retreats, suitable for all classes ; the Chief 8ecretai'y said last month that if Pai'liament desired it, he would establish tliem. Let the medical profession, the only persons capable of Aiewing this matter in all its bearings, speak out on the subject. It has latterly been the custom here to exclude medical men from Commissions on subjects Avhich they only know any- thing of, and the consequence is that froin want of knowledge, I'ecom- mendations are made to Parliament by Commissions of laymen, and members of Pai'liament think they ought to carry out these recom- inendations as if they wei'e made by experts (see the absurd blunders and mistakes of the New Inebriates' Act passed a few days ago ; it must be amended next session). I need scarcely say anything as to the medical treatment, my main dependence being on time. T give no hope ■of cure in less than three months in the mildest case, six months being reipiired in the majority of cases, and txselve months, or longer, in bad •cases ; yet the new Act says three months must be tlie maximum time ! but says thoughtlessly, the time may be prolonged if a wife and two )nedical men each make a solemn declaration, that the man that lias lived in the retreat for three months is not cured I ! Again it says, that if the patient be out for a time with the Super- intendent's consent, he shall >)e punished by being kept in longer. Again it says, the patient may be detained until as hereinafter provided ; that hereinafter refers to Sect. 10 of the old Act, which is omitted in the new. The same ignorance appears in the Lunacy Amendment Act ; moi-e faith is placed in ignorant jurymen than in medical men. The fact is, that many members of the community who have access to the public press feel it their duty to make a greater sensation when they liear of a case of doubtful insanity being sent to the asylum, tlian if that same lunatic committed half a dozen murdei's before his arrest ; but presumption is always accompanied by ignorance. T may here be per- mitted to state, that for many years T have been of opinion that where lunacy is pleaded in a capital case, the jury ought to be composed exclusively of medical experts. There has been a popular opinion, that women are more difficult to cure of inebriety than men. That has not been my experience ; women are certainly more easily managed in a retreat than men, and I think as easily cured, if not more so, than men. For sixteen years that the retreat is open, I never had a death among my female patients, and very few among the males ; only two males 1 think directly from drink. There is no mystery about the treatment, and T therefore shall not detain you with it. Australian youths are decidedly more opposed to discipline than Europeans, and therefore more difficult of cure. Any opinion formed froin practice outside a retreat as to the curability of men or women of any age, is of no ^ alue, from the fact that alcohol ■cannot be kept from tliem ; confinement in a jail does not meet the question. ^ly own opinion is, that men and women of any age can be cured if sufficient time be atibrded. I believe tliat twelve moiiths in a retreat will cure 80 per cent., six months 60 per cent., three months 30 per cent., Init in a shorter time than three months, I only expect recovery, not cure. Too frecjuent visits, and too much correspondence, will hinder cure. Vicious patients are mostly drunkards, and lequii-e 870 INTEKCOLOXIAL MEDICAL CONGHKSS OF AUSTRALASIA years for cure ; .1 penitentiary is their pro})er place, not an inebriate retreat. I shall now, with your permission, venture to make a few remarks that may be useful to the younger members of the pi'ofession, in relation to drink. The tirst is, that if they are called to a suckling baby in convulsions, they make special enquiiy as to whether the mother takes gin, especially if there be a succession of convulsions. Another is, never to recommend spirits of any kind to a nurse for the sake of the child, under the impression that it would impi-ove her milk in quantity or quality ; any nurse that cannot do without alcohol, ought not to suckle at all. Be extremely careful in prescribing spirits to patients, whatever quantity you order will be exceeded and continued longer than you intended. Women will absolutely deny to the medical man, even to their husbands, that they take alcohol to excess, or at all, but attribute their state to nervous debility. When you find a man, especially a publican, who cannot take his breakfast without alcohol, tell him he is on the straight road to inebriety. Warn the police not to put a man helplessly drunk into a cold cell ; discourage the use and abuse of tobacco, as well as of alcohol, by example and advice ; do these things as a conscientious and n;oral duty, and when so acting, fear not pecuniary consequences. The trust and confidence bestowed by patients on conscientious medical men is exti'aordinary, and where olienee is taken against moral ad^ ice, the medical man feels that he performed a sacred duty. AUSTKALIAN I.UNATIC ASYLUMS— REMARKS ON THEIR ECOXOMIC MANAGEMENT IN THE FUTURE. By W. L. Clelaxd, M.B., Cli. M. Edin. Eesident Medical Officer, I'aikside Lunatic Asylum, South Australia. In selecting a subject for the consideration of this Section of Psychological Medicine, I have endeavoured to choose such a one as would have a distinct l)eai'ing on the fact, that this Association is an Intercolonial Australian JVIedical Congress. As Australian alienists, we haAe to deal with two important factors pertaining : — (d) To the social and political constitution of the people, which is essentially democratic. (b) To climatic influences, which admit of a continuous out-of-door life. It will be the object of the following remarks, to point out how one or both of these factors cannot l)ut fail to produce its impre.ssion on the management of the asylums of the future. Tiiose who are wise, will not wait to have these impressions rudely thrust upon them b}' an imperious necessity, but by a timely provision will so arrange their ordering as to be found standing "at attention" when the .searching light of public criticism sweeps over them. It will therefore not be AUSTKALIAX LUN'ATIC ASYLUMS. 871 unbecoming to enquire on wli.it lines should the management of lunatic asylums be most justiried in striking out a course, that shall \)e essentially Australian in its eiiai-aeter, and practical in its aims. It must be admitted, that in the Australian colonies the tone of society is more essentially democratic than in the mother country. This, consequently, cannot fail to produce a cei'tain influence on the positicm of the Medical Supei'intendent of any large institution for the insane, as regards the public at large. One of the peculiarities of a pronounced democratic form of society, is to discount or even to question any prescripti\'e right that may l)e advanced by any particulai' individual or class of individuals. Hence, is noted a certain intolerance of any professional assumption. The democrat cries out, away with your titles and professions and parchment certificates, and let us see what you can do, and to that extent we will believe in you. How does this atlect the relation of the medical man to the care of the insane? To a medical audience, to assert that lunacy is a disease of the brain, and that lunatic asylums are really hospitals for the insane, is to give utterance to bald [)latitudes. 8uch assertions do not eariy the same indisputable weight to the ordinary lay mind. It may l)e possible that there is a glinnnering perception on the part of the public of the truth of insanity being a disease of the brain in acute t-ases, and that such are best under medical supervision. With respect to the chronic insane, who may be more or less manageable and quiet, the fact to the uneducated mind is less obvious. Thus we find the democratic economist asking. Why engage expensive medical super- vision for those who only i-ec|uire the shelter of a workhouse 1 There is here sucli a radical misconception or ignorance of the nature of insanity, that argument or counter-assertion would be equally thrown away. Before anything could be done to eradicate such a false conception, it would be necessary tirst to carefully educate the would-be economist in some of the first principles of psyehology. If our democrat were some Hodge l)etween the stilts of a plough, he miglit be passed by without further comment ; but when, as not infrequently haf)pens, he stands in the position of a political master, the situation becomes nmch more serious. And this is not an idle fear, for we have (mly to turn to the United States of America to see that in many instances this has been the logical outcome of this ignorance of tirst principles as regards the insane. The medical element has been reduced to periodical visits to the ostensibly sick, and not to .siqierintend the management of those suffering tVom chronically diseased brains. Even though it be admitted that, exceptionally, a layman might be found who would enter upon his duties of superintendence with the I'equisite intelligence and largene.ss of views, yet what in him would be almost plienomenal, would in a well educated medical man be simply a natural out- come of his previous training, and be to him, as it were, a .second nature. To guard against this danger of lay-superintendence, it must ])e made patently obvious to the most ignorant, that no one, excepting a medical man, is fit or cajjable of managing a lunatic a.sylum. It might be argued that there is already provision made for this in the various Australian Lunacy Acts. But this would be but a poor .safeguard, for in un.settled social conditions, an Act of Parliament can be as easily expunged from the Statute Book, as it can be ])itcliforked into it. Nothing will stand 872 INTERCOLOXIAL MEDICAL CONGRESS OP AUSTRALASIA. the ordeal of public criticism, but what is manifestly on the face of it indispensable. The safety would therefore lie in making the asylum arrangements suitable both for acute and chronic cases. It will always be admitted that the former should be under medical superintendence, and for the sake of economy of supervision, the laity will not object to the chronic insane being also included under the same management. This implies, that the asylums of the future must not be below a certain size, say a minimum of 800 patients. Much has been said respecting the advantages of small institutions, especially for acute cases. All the.se advantages can be easily secui'ed by appropriate arrangement, and isolation of the respective wards and airing courts. A distance of 300 or 400 yards is as effective a barrier to intercourse as a corresponding number of miles, and yet the former allows of one supervision. The model arrangement would consequently partake of the village character, with a small strong portion for acute cases. To allow of the requisite dispersion of buildings, a large area of ground would be a sine qud non. The advantages of such an arrangement did not fail to strike so in- telligent and receptive an observer as Dr. Hack Tuke in his visit to the Kankaka Asylum, Illinois, U.S. He says "it is a pleasant thing to see this breaking up of buildings on so extensive a scale. It must do good. The air blows more freely and freshly through this group of houses, which will soon form a little village, than it would, or could, through monster structures filled from top to bottom with the insane." To this asylum there are attached about 480 acres of land. It contains 600 patients at present, and is designed to accommodate 1500. If this " very interesting experiment " should fail to accomplish all that is expected of it in the future, it will, I am sure, be wholly attributable to the relatively small amount of land attached to it. Some fifteen years before the Kankaka Asylum was thought of, the Soiith Australian Government, acting under the enlightened advice of the then Colonial surgeon, the late Dr. R. W. Moore, caused the Parkside Lunatic Asylum to be built on the "segregation" principle. The asylum is not yet completed, but is estimated to accounnodate about 800 patients. It already partakes of the a]»pearance of a village, as the buildings are evenly distributed over the area of 135 acres of land. All that Dr. Tuke says of Kankaka, applies with equal force and truth to Parkside. The defects of the place are, a too ex})ensive and elaborate main build- ing, and a too small endowment of land. This brings us to the consideration of what should be the effect on management of our special climatic conditions. For in the lunatic, we have to deal with a sick per.son, who differs from all other sick ])ersons in being benefited by work or employment of some kind. In such an asylum for acute and chronic cases as has been held uj> as a model, there would be at least from 70 to 80 per cent, of the inmates avail- able for some industry. The nature of the climate, which allows of continuous out-of-door life, points to such industries as gardening and ordinary farming work. No more healthy and desiral)Ie occupations for a diseased mind could possibly be imagined. We have here then two important points — {a) labour of a certain kind and amount; {b) climatic surroundings exactly suited to the employment of that labour to the best advantage. This, however, is not enough. A third important point is requisite, namely — (c) turning the labour to a profitable account. AUSTRALIAN LUNATIC ASYLUMS. 873 The tendency of jjublic opinion is to rebel at all unj)roductive expenditure ; hence, every now and then some euthanistic theory is advanced for the weeding out of unproductive humanity. But whilst such theories are never likely to become ])opular, yet on the other hand, any schemes that would have for their aim the causing of the individual to produce his own fooject of the most advanced socialistic and communistic theories of the present day. This has evidently been the underlying principle in the management of many of the lunatic asylums and prisons of the United States of America ; and in some cases, the apjjlication has been attended with marked success in reducing expenditure. It aj)pears to me that unfortunately a radical error crejit into these efforts, or rather was in the methods used by which the object was to be attained. The conception of the idea of making these institutions self-supporting was a thoroughly sound one ; the channels into which the efforts were directed were, in my opinion, undesirable. These latter, in many instances, partook of the nature of handicrafts, or ordinary artisan work. As long as this was simply to sujiply the needs of the place, no objection could be taken ; but natur- ally, the requirements of these institutions for such products were quickly satisfied, and a suri)lus became available. This excess of production over consumption could not be convei-ted into something eatable or wearable without being first sold. This at once implied coming into collision or competition with other ])roducers of similar produce. These, in democratic communities, are frequently a large and demonstrative section of society. It was, therefore, not long before an outcry was made that the State was unduly competing with their industry, and taking the bread from the mouths of their children. Such a thing could nob be tolerated, and the sale of these articles was prohibited in the country in which they were manufactured. If, instead of making such articles as wooden buckets, ikc, the above institutions had devoted their energies to producing bread and meat and material for clothing, no adverse comment would ever have been made. As long as produc- tion is confined to su])plying the daily wants of the inmates, no section of society will ever object. Australian society will urge the desirability of making Government lunatic asylums self-supporting; the Australian climate, with a beaming countenance, already says —Why not? the Australian sun daily pouring upon the land inexhanstilile sup})lies of radiant energy sutiicient to warm into life the most slothful and apathetic, encourages us to try. Water may be always had for the sinking ; and our soils are unsurpassed for productiveness in any portion of the woild. Will society be far wrong then in making this demand, when sucli requisites exist as laljour, climate, sun, water, and soil. The indications then point unmistakeably to the production of the necessaries of life. To what extent can this be done"? The answer to this question will depend largely on how it is done. If the attempt is to be made a success, the ordinaiy Australian methods of tillage must be carefully avoided ; and we must look elsewhere for a model. Such examjjles worthy of being imitated may be found occasionally in England, but to a greater extent on the Continent of Europe. These aie compi-ised under the method known as the " culture mai-aichere," the essence of the .system 874 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. being to create for the plant a ))oroiis and nutritive soil, containing the necessary decaying organic and inorganic compounds, under conditions of temperature and moisture, sui)erior to those existing in unaided natural surroundings. Social economists assure us that " with cultural methods already used on a large scale, a thousand human beings living on a square mile (640 acres), could easily, without any kind of overwork, obtain from that area a luxurious vegetable and animal food, as well as the flax, wool, hides, &c., necessary for their clothing." An important requisite is, therefore, an approved method of tillage. Before we can till, a suitable area of ground must be secured. What should be apiiroximately its extent? As a working example, we may limit our attention to the size of a lunatic asylum that might be con- veniently worked by two medical men. This would be one caj)able of accommodating about 800 j)atients. The area of ground required for such an asylum should not be less than one square mile (640 acres) ; and the whole of the grounds not required for buildings and airing courts, should be inider tlie above high system of culture. It is not to be su[)posed for a moment that any institution would attempt to under- take to do this at a bound. Here, as in other things, a gradual growth and develo[)raent towards an ideal should be the aim. Existing institutions should try, to tlie extent of their area of available ground, to produce a corresponding amount of food value; and thus help to demonstrate the feasibility of procuring the whole of the necessarie.s of life, from an area of ground suited to their number of patients. Again, all future asylums should from the first be provided with an area of ground suitable for their contem])lated size. The first attempts would natural!}' be to produce some of the more easily obtained articles, such as milk, eggs, and butter, a trio that, in an institution for 800 patients, would represent the respectal)le sum of something like £2000 per annum. This should be ])i'acticable with any asylum of like number of patients, that lias, exclusive of ground taken up by buildings and pleasure grounds, an area of arable land of fifty acres in extent. At the same time, the production of the necessary fruit and vegetaljles, jams made with honey instead of sugar, osiers for baskets, tobacco, oil and fat for soap, and fibre plants for mats, itals for temporary reception. New South Wales, Queensland, Victoria have also separate asylums and hospitals for criminal insane. New South Wales, New Zealand, Queensland have licensed houses. New Zealand, Victoria, boarding out. Victoria, paying asylum and philanthropic asylum; licensed hou.ses ta be gradually abolished. Medical and judicial powers to go hand in hand, the judicial order lieing given upon the medical testimony. This association is complete in New Zealand, where the Resident Magistrate has to order what are called ])rivate admissions in other colonies. The checks and safeguards to wrongful admission and detention are both numerous and efficient. In the vast majority of instances, all alleged lunatics are committed by two Justices on the certificate of two medical men. Exceptions occur, as in the case of paupers, where South Australia and Western Australia allow one Justice, and Tasmania two Justices, to commit on one medical certificate. The other exception is in the case of a dangerous or criminal lunatic who, in South Australia or Western Australia, can be committed with or without a medical certificate at all, if one is not readily obtainable, as may often happen in these si)arsely populated colonies. The Justices can examine at private houses if they wish in most colonies ; but New South Wales jealously guards against any al>use of this power by enacting a ])enalty up to .£100 sterling if the Justices fail to report the fact of private examination. Private admissions ai'e in all cases obtained by an order or request from a relative or friend, supported by two medical certificates. New South Wales and Queensland require the signature to this request to be authenticated by a Justice or Minister of Religion, while New Zealand requires the person signing the order to make oath before the Resident Magistrate. In all the colonies, persons may be found lunatic by inquisition or order of the Supreme Court, and committed to asylum. The methods of dealing witli insane criminals ari; practically the same in all the colonies; but in Tasmania the Sherifi', as well as the two medical prac- titioners, must be satisfied as to the insanity before removal to an asylum can take place. The question whether a jjerson is sane or insane, has been rightly held here, as elsewhere, to be a medical one. It is a duty that has for genera- tions past been thrust upon the profession, and like many another that falls to its lot, a most disagreeable one at best. Its discharge has caused 2l 882 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. most respectable members to be more than suspected of lieartless con- spiracy and downright dishonesty. Laymen have not hesitated to set themselves up as superior judges to si)ecia]ly qualified medical men on the question, regardless of the fact that the possession of a medical qualiticatiou presupposes a more liberal education, and a still greater experience of human nature than falls to the lot of the average man. Much interesting food for i-eflection could be obtained by an observation of the different degrees of faith reposed in medical men in these matters by the different colonies, and to what extent they accept lay opinions as of weight in cases of insanity. All require each alleged lunatic to be certified by two medical men, with the exception of South Australia and Western Australia, where, as I have already shown, one is sufiicient in the case of paupers ; even one may be done without if a lunatic is dangerous and a certificate not readily obtainable. Only in the case of a prisoner under sentence of death can I find any legal provision for more than two medical men inquiring int(5 the insanity before committal to an asylum. With the exception of New Zealand, which allows the examination to be made jointly in certain cases, the medical man must always examine separately from not only the one who has already given a certificate in the case, but any other. The medical certificate must state facts, distinguishing between those indicated by the examinee, and those communicated by others. The only exception to this rule occurs in Victoria in cases that are brought before justices, when the certificate only contains an expression of opinion, without showing any grounds for it. This is a matter calling for remed}', as too great facility is thus given for })erfunctory examina- tion, which is further intensified by magistrates in busy courts only examining one medical man, and even then not requiring depositions to be taken. Hence the patient arrives at the asylum with little or no information to guide the medical officers, and a certain amount of colour- ing is given to the stories that are not wanting of a certificate of insanity having been given, when the wrong man has been examined. The medical man is paid also, not for his examination of the patient, but for his certificate of insanity. This can only be regarded as a menace to the liberty of the subject, and has been the reverse of satisfactory to con- scientious men, who have found themselves unable to give the required certificate. The examination must be made not more than seven clear days before admission in New Zealand, South Australia, Victoria, and Western Australia, while in Tasmania and Queensland this time is extended to ten and fourteen days respectively. In New South Wales, in private admissions, the time is ten days, but in police cases, twenty-eight days are allowed from the date of the last medical certificate. The restriction upon medical men, preventing them from signing for a particular patient for whom one certificate has ah'eady been obtained, extends from the simple prohibition of a " partner or assistant," as in South Australia, Tasmania, and "Western Australia, to most elaborate I'estrictions in New South Wales. " Father, brother, and son," ought certainly to be added to " partner and assistant," as the mutual influence must be regarded as greater. Under the Victorian law, I have had to refuse certificates signed unwittijigly by such relations. LUNACY LKGISLATIOX IN IIIK AUSTliALlAN COLONIES. 883 When, owing to .special iiic|uii'y, a patient liass been admitted on one certiticate only, tlie procedure to make lengtliy detention legal, varies considerably. All New South Wales and Queensland recjuire is one other certiticate within fourteen days; Tasmania within tifteen days. The remaining colonies demand two more certificates within three clear days. If the urgency be distinctly proved, I think one additional certiticate quite sutKcioit, as two would have suthced in the tirst instance. In the great majoi-ity of cases the patients are in poor circum- stances, often reduced thereto by the pre-existing lunacy that has not, or would not, be recognised as sucli. The legal means provided, to justify the detention of the })atient after his admission, aie both numerous and ethcient. They are exactly the same for lunatics admitted through the law courts as for those sent privately by their i^elatives or friends, although ditierent methods exist in different colonies. In Xew .South Wales, New Zealand, (^)ueensland, and Victoria, within seven days of admission the Medical Superintendent must forward to tlie State ofhcial head of his dejiartnient a personal examination certi- ficate as to the mental and bodily state of his jiatient. 1 n South Australia and Western Australia, if within forty -eight hours of the admission the Resident Medical OfMcer and the officer next in authority (probably a layman) are not both satisfied as to the insanity of the patient, a meeting of the Permanent Board of Inquiry mtist be held within three days to decide the qttestion, and of this Board, the Ooxernment Medical Officer (the Colonial Surgeon) is Chairman. Tasmania appears to consider that con)mittal to her asylums is not to be lightly obtained. Having full confidence in her officers, she is not afraid of unnecessary detention, as the powers of discharge given to the official visitors, and the responsibility thrown upon the Medical Super- intendent are, I think rightly, considered more than sttfficient to prevent such. In marked contrast with this simple faith is the elaborate machinery of medical examination at the asylum, by outside men, provided by the latest Victorian Statute. Under this Act, the Super- intendent is allowed to fortify his opinion of the sanity of a reception- house patient, before discharging him, by calling in another practitioner. If this man does not concur, another is called in as arbiter, and upon his decision rests the discharge of the patient, or his committal to asylum. Fortunately, the Superintendent has the choice of asylum to which the patient shall be sent, as the law might have placed him in a still more ancmialous position, by calling upon him to ti'eat as insane a ])atient whom he did not believe to be so. If the Superintendent considers the patient insane, he is compelled to call in two medical practitioners. If they agree with him, the patient is to be sent to asylum. If they agree with one another that the patient is sane, he is to be discharged; while if they difier in o])inion, the services of a police magistrate and another medico are to be called into requisition to decide the question. These provisions will, I venture to jiredict, occasion a great amount of unnecessary trouble, especially in recurrent maniacal and obscure delusional cases. This might have been saved by placing more reliance U])on the Superintendent's opinion, which should carry more weight, if only from his opportunities of examination extended over from at least three to twentv-eight days. Whereas, the oi)inions that over-ride his 2l 2 884 IKTEllCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. are formed Ti])on one examination only, wliich may easily cliance to take place during a lucid interval, ft would have Ijeen too much to expect that that reluctance on the part of e\-en intelligent laymen to consider insanity as the result of disease, and a special branch of medical science — a reluctance that is exhibited by even the learned judges of (rreat Britain — would have been so far eradicated by the transplanting of the majority of our legislators to Australia, as to induce them to frame laws, giving anything like full weight to the opinions of expeiienced alienists on questions of insanity. I think we must liowever congratulate ourselves in Victoria, that such prominence has been given to medical opinion in the new legal departure which, with the establishment of this section of the Congress, will I hope be the beginning of V)etter things. The laws have pierced the asylums with means of inspection, that would more than suffice to demolish the abuses of fifty years ago. In many instances no distinction is made between licensed houses and asylums in this respect, oblivious of the fact that, in the one case patients are being kept for profit, wdiile in the other, the officers can have no personal motive in detaining patients. In New South Wales, New Zealand, Queensland, and Victoria, we have inspectors whose whole time is occupied with asylum matters, and who have able assistants in the Official Visitors, who are usually chosen from the medical or legal profession, or are members of the Legislature, or magistrates. In South Australia and Western Australia the same officers exist, but the inspectors have other duties to i)erforni in addition. In Tasmania, the inspector's duties are jterformed by a Board of three official visitors. It is one of the duties of all these to see every patient in the asylum at each visit, to listen patiently to and inquire into all complaints, and to pay special attention to the newly admitted. They have the right of entry at all times ; and in South Australia, it is specially enacted that any Justice has the same. In South Australia and Western Australia, anj- two householders can obtain a meeting of the Board of Inquiry into the case, if they allege the sanity of ])atient has not been inquired into for three months. In the other colonies, any complaint addressed to the Inspector or Official Visitor, would cause full inquiry to be made into the special case. Victoria has, in addition, just provided for the annual examination of all patients by specially appointed medical practitioners. This is I consider, a move in the right direction, as it altogether prevents the possibility of any patient being over looked, and is a duty that, with its attendant clerical work, could not have been discharged by the asylum medical staff in its undermanned condition. The laws have fully provided for the discharge of patients on recovery, and the means of obtaining it are numerous. Admission to an asylum does not necessarily mean perpetual confinement therein. There is more uniformity in the method of dischai^ge than of admission, and without much disarrangement of the sections of the various statutes, it would be easy to draft a law of discharge common to all the colonies. Discharge will be considered under three heads : — (1) Discharge by order of relative or friends. (2) Discharge by action of asylum authorities. (3) Discharge by order of Supreme Court. lunacy legislation ix iiie ausihalian coloniks. 885 (1) Discharge by Order of Eelative or Friexds. In all but New Zealand and Queensland, the person who signed the request for admission, or his legal representative, may order the discharge of the patient, unless the medical officer certifies that he is dangerous or untit to be removed, liut the insjiector or other superior authority has the power of over-riding this certificate. It is well that this method is little availed of, as its adoption would be constantly against the Superintendent's advice, and would lead to frequent relapses and other damage. In New Zealand these dangers are guarded against by the proviso, that the ))erson who signed the request must first obtain the consent of the Colonial Secretary, Insjjector, or Medical Officer to the discharge, and then apply to the Resident Magistrate for a discharge warrant. Kenioval by £50 bond, entei-ed into with the Inspector, is a method in operation in New Zealand and Victoria, and perhaps in other colonies. It operates as a discharge from the asylum, but is altogether unsatisfactory in the event of subsequent recovery. In New South Wales, the Inspector-General, as an official visitor, and in Queensland, the Minister, can allow friends to undertake the care of a patient, with the approval of the Superintendent or Medical Officer. Endeavours are made to lessen overcrowding, by making monetary allowances to indigent persons for so taking cai-e of their relatives in these colonies. (2) DiSCHARCE BY ASYLUM AUTHORITIES. The simplest method — almost the only one in use in Victoria, and adopted also in New South Wales, New Zealand, and Queensland — is for the Inspector, Official Visitor, or Superintendent simply to certify that the patient is detained " without sufficient cause." The issue of this elastically-phrased certificate to a superior authority, is followed by the discharge, except when a criminal is returned to gaol, or a Queen's pleasure man is detained until the pleasui'e is notified. In South Australia, Tasmania, and Western Australia, any two visitors, with the advice of Resident Medical Officer, may order discharge, and this apj)ears to be the regulation method. South Australia and Western Australia have their laws further alike in that — (1) Any three visitors may order the discharge, and in the case of a paupei-, any two may do so. (2) The Resident ]Medical Officer, or any two visitors, one being the Colonial Surgeon, may order the discharge of a patient committed as " dangerous or criminal," on receipt of certificates of sanity from two medical men. This provision can Ije set in motion apparently either by the asylum authorities, or relatives or friends. In New South Wales and Queensland, the Inspector-General, or Official Visitor, has full discretionary ])0\ver of di.scharge, whether recovered or not, after he has taken the advice of the Superintendent or Medical Officer. In Queensland, the Minister can order the discharge upon the receijjt of a statutory certificate from the Superintendent (or two medicos, if he be a layman), that the patient is "recovered and fit to be discharged." 886 INTEKCOLOXIAL MEDICAL CONGHKSS OF AUSTRALASIA. In New Zealand, the certificates are worded (a) of unsound mind, or (6) in such a condition that can be liberated without danger to self or public, and no necessity exists for further confinement or detention. It will be seen, that the general principle underlying these proceedings is, that a medical certificate of suitability is followed l)y the discharge, as a natural consequence of the same authority having led to the admission. The opinions of intelligent laymen have expression in the voices of the ofticial visitors. In New South Wales, New Zealand, Queensland and Victoria, the Medical Attendant, Superintendent, or Kee})er, can ol)tain a veto to a discharge proposed against his judgment, by tendering himself for examination by the Inspector or Official Visitor, and giving written reasons of objection to the political head of the department. (3) Discharge by Order of the Supreme Court. If the foregoing numerous methods fail to secure freedom, there is still the right of legal redress, by an appeal to the Supreme Court. This exjiensive method has verv rarely been had recourse to ; asylum phj^sicians know full well, that so far from patients being unnecessarily detained, grave risks are constantly being incurred in granting what afterwards prove to be undoubted cases of premature discharge. Any- one specially interested in a patient can have the matter brought before the Su})reme Court, which can sit in private, and any judge of which has absolute authority to oi-der the dischai-gp. The patient himself can set the machinery in motii)ii in the.se democratic colonies, by a simple letter addressed to the Minister, which must be forwarded unopened. The Supreme Court also has the sole authority to order the discharge of any person whom it has found lunatic by inquisition. After a survey of the different methods of discharge, it will be recognised that complete provision is made, and that a patient's exit from an asylum, when the public safely i)erniits, is quite as easily obtained as even his voluntary admission into it. I will conclude, Mr. President and Gentlemen, by saying tliat, although many debateable subjects are raised, the ground travelled over is too extensive to ]iermit of the Avhole paper being the subject of profitable discussion. The issues are too numerous for aiay practical good to result at present ; but I will hope, that the result of my labours in collating this information from the various statutes, will be found useful in the ])reparation of papers upon some of its points for future meetings of the Congress. The comi)arisons instituted will also, I trust, serve to make us better acquainted with the laws under which our neighbours have to act in their dealings with the insane. What we already know, but what the general public is remarkably slow to believe, is also I think clearly demonstrated, that admission to an asylum is hedged about with such precautions, the i)robal)iIity of wrongful detention is so carefully guarded against, and discharge on mental recovery is rendered so easy, that it is practically out of the question that sane persons can be immured in our lunatic asylums. The Members tiianked Dr. Armstrong for his paper, and a sti'ong expression of opinion was given l)y all members against that portion of the further Amended Lunacy Act of Victoria, which provides for the TRAINING OF NURSES AND ATTENDANTS IN INSANE HOSPITALS. 887 inspection of asylums once a year liy an outside medical man. It %vas thought that the asylum officials -were the best judges as to the sanitv of the patients, and that the Act throughout threw discredit on them in a manner that was highly undesirable. Private asylums were considered unnecessary, except for verv wealthy })eoi)le. Dr. Armstrong in replying, stated that though he considered it was practically out of the question that sane persons could be immured in our asylums, he nevertheless defended the a]ipointment of an outside examiner, as an additional safeguard. THE TRAINING OF NURSES AND ATTENDANTS IN HOSPITALS FOR THE INSANE. By W. C. Williamson, M.D. Medical Oflficer, Hosijilal for Iiisauc, Parramatta, N.S.W. The question of establisliing some system of training for nurses and attendants engaged in the care of the insane in our asylums, has been, in recent years, one of very great interest. The subject is an old one revived. Many years ago, close on half a century, the need of reform in the class, character, and education of persons entrusted with this responsibility was recognised. Curiously enough, though our co-workers in general hospitals have made trained nurses what they are, the honour of leadership in the ideas of nursing reform belongs especially to Drs. Jacobi and Pinel, two alienists whose names will be for ever held sacred as early pioneers in the humane tieatmenc of the insane. Tliere has always been a difficulty in obtaining nurses of the right kind for service in our hospitals for the insane. Samuel Tuke, in 1841, describing the trying and arduous character of the work of caring for the insane, writes:— -" Can it be surprising if it be so difficult to meet with per.sons to till properly the post of attendant on the insane, that instances of neglect or abuse so frequently occur 1" Dr. Kirkbride, about the same time, in the United States, was commenting on the same trouble, and thus defines his conception of an ideal nurse : — '' A person of high moral character, of good education, strictly temj^erate, kind and res])ectful in manners, cheerful and for- bearing in temper, with calmness under every irritation, industrious, zealous and watchful in the discharge of duty, and above all sympathetic with those under care. No wonder," he added, " The services of such an individual, after proper instruction in the performance of duty, would be invaluable." Nurses of this stamp, however, were not to be had, and I do not think there could have been much at this ])eriod to choose between the hospital and the asylum pattern. No change in either service took place till Florence Nightingale began her noble work in the Crimea. Her efforts to ameliorate the sulferin^s of our soldiers wounded in that campaign, and her organisation and management of the nursing in the camp hospitals laid the foundation 888 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. for her future labours on her return to England. To her, the entire Avorkl owes a permanent debt of gratitude for the reforms of modern nursing. Coincident with Miss Nightingale's labours in the Crimea, we find Dr. W. A. F. Browne delivering at the Crichton Institution in 1854, tliirty lectiires to his asylum staff, with the express object of elevating the standard of nursing efficiency. Dr. Mackintosh at (xartnavel, made somewhat later an effort in the same direction, and gave instructions to his attendants, taught them to take notes, and observe physical alteration in patients, &c. These efforts were unattended with the success they deserved, and the movement lapsed. Then, as years went by, and the marked success of the I'eform in general nursing was noted, and while superintendents were bewailing the scarcity of suitable asylum nurses, there became a])parent the possibility of educating the mental nurse on the same lines as her sister trained for bodily nursing. Dr. Clouston, of Morningside, in a paper read l)y him in 1876 before the Medico-Psychological Association, on the question of " Getting, Training, and Retaining the Services of Good Asylum Attendants," pointed out that there were at the end of 1875 in Great Britain about 72,000 insane persons, for whose care and treatment some 6000 nurses and attendants wei'e necessary. He stated the raw niaterial of the right kind out of which they endeavoured to make good attendants was, and had been, most difficult to obtain, and he showed how unsatis- factory this condition of things -svas. It made matters hard for the proper management of asylums, was detrimental to the insane, inter- fering with the comfort and happiness of some of them, prolonging the malady of others, preventing the recovery of a number, and causing risk to the lives of not a few. He described, in fact, this attendants question as the one causing most anxiety to many at the head of asylums. To obviate to some extent the difficulty of developing his raw material into satisfactoi-y shape, he had found the early placing of his probationers in small classes in the sick wards under a careful and competent senior, to be a step in the right direction. In this way probationers came into contact with the sick in mind and body, learned tlie individual wants of tlie insane, became impressed with the fact that they were really p-itients, got into good habits and right ways of thinking generally, and proved to be far better qualified for the more regular work of ward routine. The basis of action here was evidently to impart at the outset some knowledge of bodily nursing, at the same time bringing those cases of insanity in which more than ordinary care and attention were required, more prominently under the observation of the young attendant. Dr. Clouston foresaw the marked influence which tlie fii'st few months of asylum life have upon the future of the j)robationer, and he rightly determined to make tlie best use of his opportunities. No systematic teaching had up to this time been attempted, but tlie lapidly advancing importance and benefit of trained nurses in general hospitals and ehe- where, gave fui'ther imjietus to the proposals and practice of tlif distinguished Superintendent of Morningside. Dr. Campbell Clark, of the Glasgow District Asylum, Bothwell, began in 1881 (not witliout distrust of the lesults), a course of eighteen TH AINING OF NURSES AND ATTENDANTS IN INSANE HOSPITALS. 889 lectures to liis start", the subject inattev tliereof Ijeing ajipavently })ractical mental nursing, put into as siui])lf' form as possible. The success of this departure was so marked that he ventured on a second course of lectures, and again tlie result was most gratifying. The latter series embraced a wider field of teaching, and prizes and certificates were eagerly competed for at the examinations on the conclusion of the course. In Dr. Uaui])I)ell Clark's i)aper, read before the Medico-Psycliological Association in 1883, lie stated as the result of his somewhat varied experience :— " (1) That too great a barrier existed between officers and attendants ; (2) That the mental and moral qualities of attendants w(3re not utilised as fully as they might be, and (3) That attendants require to be individualised as well as patients." In working out his scheme, Dr. Clark ])ut on i-ecord his opinion that, " We are becoming more and more fully impi-essed with the idea, that the asylum of the future will partake largely of the hospital type." In America, the necessity of reform in the nursing of their insane, had also been recognised, and for some years liad occupied the minds of asylum superintendents. In 1879, the plan of the McLean Asylum Training School was definitely determined upon. "The object was to create a school, not simjily for the instruction of attendants on the insane, but to fit young women, as in the general lios})itals, to undertake nursing in all its branches, wish special qualifications for the cai"e of cases of nervous and mental disease." I have no hesitation in expressing my belief that the work done there by Dr. Cowles, as fully set forth in the paper on " Nursing Reform for the Insane,' read by him in September 1887, before the Psychological Section of the International Congress at Washington, embodies the most important advance in our modern methods of caring for the insane. Dr. Cowles had not, up to the time of v/riting his paper, extended his system of training to his male attendants, but the success of tlie movement amoug his nurses was such as to leave no doubt in the reader's mind he intended shortly to include his men in the scheme of nursing reform. In February 1884, a sub-committee of the British Medico- Psychological Association prejtared an ofiicial handbook for the special instruction of attendants, and since then a considerable amount of literature has been published on the same subject. I am glad to say that reform in this direction has not been confined to the few asylums already mentioned. In our own colony, Dr. Sinclair has, at Gladesville, for the jmst two winters carried out complete courses of lectures and ward training, both for nurses and attendants, and I shall have much ])leasure later on in giving an outline of tlie system practised there with very great success. The practicability of establishing with success a legular system of training being now assured, the development and extension of the Scheme can only be a matter of time. In reviewing the i)resent position of trained nursing in general hospitals, we are at once struck with the enormous advance it has made within the generation of its existence, and tliat, not alone in the marked efficiency of its service, but — another ■excellent test — in the appreciation with which it is held by the public. Tlie employment of trained nurses may now be said to be universal. We have nursing departments for the army and navy existing in our large military and naval hospitals in England, and we find that in time 890 IXTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA, of war these nurses are seat ovit for service in the hospitals wliich receive the wounded from the field of battle. In all civilised countries, there are to be found training schools attached to the larger and more important hospitals, where nurses are carefully prepared for their future mission. In public and in private, none but trained nurses are employed, and we shall probal)ly tind ere long Tuany of these qualifying themselves specially — on the same princi})le as do our professional brethren — for attendance on special varieties of bodily illness. In New South Wales, Sir Henry Parkes long since recognised the wisdom of having a similar system to that established at St. Thomas', in London, under the supervision of Miss Nightingale, and some twenty years ago, acting on the recommendation of Sir Alfred Roberts, then one of tlie Surgeons to the Sydney Infirmary, obtained the services of several trained nurses from England, as a nucleus from which nursing i-eform might lie extended in the mother colony. AVe now tind appoint- ments on the nursing staff of our hospitals the object of keen competition, and the list of a))plicants for training always much larger than can be accommodated. Trained nursing, in short, has now been elevated into a profession. It enlists the best sympathies of mankind, atibrds a large field of noble usefulness, and |)rovides a valuable and self-supporting occupation. When we turn froui this view of nursing, as it exists for bodily illness, to the present condition of nursing for the insane, we naturally say to ourselves, "If the nurse of one sick of a physical disease is sa mucli improved by training, how infinitely more important is it that those who are to minister to a mind diseased should have a special teaching 1" I am inclined to think that in the past the medical officers have put too much faith in the means which they personally brought to bear upon the recovery of their patients, and have overlooked, or not made sufficient out of the association of the nurse or attendant with the patient. We recognise how great is the influence of surroundings upon the insane. We improve their accommodation, brighten their rooms, give them amusements and occupation in variety, but we have not yet made for them ideal nurses. If we omit to train the nurse to understand the patient, there exists a barrier between the two, caused by indifference, ignorance, and lack of syuipathy on the one hand, and distrust, perhaps fear, on the other. If, as there is little reason to doubt, success in the treatment of our insane depends largely on the men and women to whom we confide the trust of our patients, and the fulfilment of our instructions, the neces- sity of providing the best possible type of nurse and attendant, and of training them thoroughly for their important duties, is evident. In too many instances the system hitherto has been to allow the I'aw material to develop of itself, without assistance or instruction worthy of the name from the medical officers. A copy of rules, a few hints from matron or chief attendant, and the new comer enters upon his work. Nurses and attendants some time in the service of the in.stitution are not found to bother themselves about new hands, and if there be any training or exan^jle sliown them, it cannot, I fear, always be said to be what is desirable. Almost invariably a lazy, indifferent senior will sjjoil the juniors in the same ward by force of example, and the first six or twelve montiis mav well be said to make or mar the future of the THAIXIXG OF \UHSK8 A\D ATTENDANTS IX INSANE HOSPITALS. 891 probatioiaer. The difference between a truined nnrsing staff and one allowed to develop of itself, is just the difference between skilled and unskilled labour. Acce{)table applicants for the posts of nurse or attendant must have had a fair general education. They are usually under the age of 25 years. They have had, in the large majority of instances, no previous knowledge of nur.sing or experience of the insane. The appointments sought for are permanent (de)>endent on good Itehaviour). This is, in itself, a considerable attraction. The rates of pay are good, and i)ro- inotion to senior grades follows on efficiency and length of service. With us in New South Wales — for all who elect to ])articii)ate in the advantages of the Civil Service Act — pensions are attainable when unfit for further work tlirough age or ill health. Yet, despite these inducements to enter the asylum service, we have, from time to time, actual difficulty in filling vacancies on the nursing staff with material of the right kind. The reasons seem obvious. There must be — as compared with ordinary nui-sing — a want of interest in their patients, inasmuch as in hospitals there is a rapid change of cases, with visible and speedy imjn-ovement in many instances to which nurses can personally contribute. Whereas, in asylums, interest and zeal are apt to flag under the prolonged character of the disease; when there is but little, if any, change from day to day;, when convalesence is slow, and when patience and nursing are not quickly rewarded by results, the work is frequently unpleasant, and there has been no attempt made, till very I'ecently, to develop the senti- ments which should animate nurses. They have been left too much to their own devices, have had but little interest taken in them by their superior officers, and, so long as they fillee to carry carefully out the Board's directions to persons receiving pauper patients. *' Every pauper lunatic, whose residence in any private dwelling has been sanctioned by the Board, must be visited within three weeks after 1 HOUSING OF THE INSAXK IN VICTORIA. 903 bucli sanction lias been giiinted, and at least once every three months thereafter, b}- a medical man appointed to perforin that duty by the Parochial Board of the parish to which the lunatic is chargeable, unless the General Board shall, on special application by the Inspector of Poor, otherwise regulate such visits; and the medical officer shall, at every such visit, enter in tiie visiting-book for pauper patients in private dwellings, which shall be kept in the house in which the lunatic resides, a report of the mental and l)odily condition in which he found the lunatic, with any suggestions or recommendations for improving the condition of the patient which he may think desirable ; and any medical person who shall make any such entry without having visited the patient within seven days previous to such entry, is liable in a penalty not exceeding ten pounds for every such oftence. " Suggestions or recommendations for improving a patient's condition, recorded Viy the medical officer, shall be at once reported V)y him to the Inspector of Poor of the jtarish to which the lunatic is chargeable, who shall either see that they receive innnediate effect, or shall report to the (reneral Board his reasons for not carrying them out. " It shall be the duty of the Inspector of Poor of the parish to which an out-door lunatic is chargeable to visit the patient at least twice a year, and to record the visit on its proper page in the book in wliich the medical officer's visits are recorded; and in the event of the lunatic residing beyond his jiarish of settlement, it shall be the duty of the Inspector of that parish, if he does not visit the patient himself, to jirovide for his being visited by the Inspector of Poor of the parish of residence; in which case it shall be the duty of the Inspector of the Jiarish of settlement to assure himself that these visits are regularly made and recorded. "If a pauper lunatic under the sanction of the Board is regarded by them foi" any reason as untit for residence in a ])rivate dwelling ; or if any of the conditions as to accommodation, guaidiansliip, treatment, or visitation is not observed, the Boai'd may withdraw their sanction, and require the patient's removal to an asylum ; and any paujter lunatic who has been removed from an asylum, and boarded out, shall be sent back to it within fourteen days after the Inspector of Poor receives the order of the General Board to that eftect. " No pauper lunatic residing in any private dwelling shall be removed from the i)oor-roll unless by a minute of the Parochial Board granted at a duly constituted meeting, and unless sufficient evidence be produced to the Parochial Board that his care and treatment will be provided for in a manner which they regard as satisfactory. When a pauper lunatic who has been lemoved from an asylum is ordered by the General Board to be sent back, the patient's relatives cannot lemove his name from the poor-roll without tlie Board's sanction. " When a jtauper lunatic in a private dwelling ceases to l)e chargeable as an out-door jtatient, by removal from the poor-roll, or recovery, or removal to an establishment for lunatics, or death, intimation thereof must l)e given to the General Board within fourteen days. A notice of recovery must be accom})anied l>y a certificate of sanity, and in cases of death, the cause iihould be stated. Kemoval to an asylum must be effected by application for a Sherifi's order on Form A. 904 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. " Parliamentarii Grant in aid of the Cost of Maintenance of Paxq^er Lunatics. *' No claim for participation in the Pai'liamentary grant in aid of the cost of )naintenance of pauper lunatics is adniitted, unless the General Board give a certificate that the patient has been necessarily detained, and properly cared for, in the place in which he svas maintained during the period for wliich the claim is made. " A claim made on account of a pauper lunatic maintained in an establishment for the insane, will be invalidated : — " (1) If there is reason to believe that his mental or bodily health is injuriously affected by residence in the institution in which he is detained. " (2) If his condition renders him unsuitable for treatment in the particular class of institution in which he is placed. " (3) If the Board shall be of opinion that he is detained in an establishment for the insane, notwithstanding that he could be satisfactorily provided for in a private dwelling, were reasonable efforts to find a proper guardian made by the Inspector of Poor, and adequate payment offered by the Parochial Board. " Claims made on account of paujjer lunatics maintained in private dwellings under the Board's sanction, will be invalidated, in the event of any one of the following conditions not being complied with : — " (1) They shall be comfortably housed, clothed, and fed. " (2) They shall be in every way as well treated as other members of the household. " (3) They shall receive such personal care and attendance as will ensure tlieir comfort and safety. " (4) Every reasonable effort shall be made to improve their condition, and contribute to their happiness. " (5) The Inspector of Poor shall make two visits yearly to each patient, and shall record them in the A-isiting book, as prescribed by the Board. " (G) A Medical Officer, appointed by the Parochial Board, shall make four visits yearl}' to each patient, and shall recoid them in the visiting book, as prescribed by the Board." Motives of economy help the Parochial Boards to regard the system Avith favour, since the average expense in boarding out pauper lunatics is less than that required for their maintenance in asylums, and the cost of asylum acconnnodation is altogether avoided. From this it will be seen that lunacy and pauperism go hand in hand, the laws in each being to provide for care and treatment ; lunacy producing pauperism, and pauperism lunacy. Concerning tlie guardians, the relatives are naturally preferred where suitable, but strangers are found to do better in a laige proportion of the cases. To sum up, the general views in Scotland are, that " no one questions tlie value of boarding out i)au])cr })atients, from suitable cases, suitable HOUSING OF Tin-: IXSAXK IN VICTORIA. 905 guardians, and proper supervision," bnt tliat such a combination is fre- quently difficult to obtain, and that it is only a poor-house where a profit could be made out of six or seven shillings a week, if the patients were not neglected. It must also be remembered that there is no royal road to the selection of the patients, as many likely ones prove unsuitable soon after going out, and somewhat unlikely ones agreeably disappoint us, yet the question is mainly a tinancial one, though mental improve- ment occurs through its adoption, as it does in our existing probationary system of trial leave. " It has been frequently pointed out in the reports of the Board, that the number of persons in a community who are treated as lunatics d«;pends on various circumstances. Among the most im]>ortant are the stage of develoi)ment in civilisation to wliich the community has attained, the density of the population, the facilities which exist for the treatment of persons as lunatics, and the relation of insanity to the system of relief of the poor. From the complex operation of such causes, the proportion of pei'sons treated as lunatics has been materially altered in most of the Scotch counties since the enactment of the present lunacy law. In the county of Suthei'land, for example, the number of persons in establishments for the insane was in 1(^59 equivalent to only 4') j)er 100,000 of the ])oi)ulation, and it was in 1886 equivalent to 27o per 100,000. In the county of Ai-gyle it was only 95 per 100,000 in 1859, and in 1887 it was 355 per 100,000. The changes in these counties are no doubt chiefly due (1) to the jirovision of more con- veniently-situated asylum accommodation ; and (2) to the operation of the poor-law, in combination with the Government gi'ant in aid of the maintenance of i)auper lunatics. Theie has been an increase in the proportion to po{)u]ation of pauper lunatics in asylums in every county, except in Midlothian, the increase for the whole of Scotland being equivalent to a rise from 102 to 184 ])er 100,000 of the population. It is lemarkable that, according to the figures in the table, there was in the case of the county of Midlothian, instead of an increase, a fall per 100,000 from 185 to 173. Had the whole of Scotland theiefore been in the ])o.sition of Midlothian, the total figvues would, as regards the statistics i-elating to establishments for the insane, have given the appearance of a decrease in the amount of pauper lunacy in proportion to pojmlation, instead of giving, as they actually do, an a|)j)earance of a large increase. It is remarkable also that the ])roportion which Scotland as a whole has now reached should be almost exactly what was shown Viy Midlothian at the beginning of the period to which our statistics refer. This almost seems to justify the assertion that pauper lunacy in Midlothian had, at the conunencement of the period, reached or rather slightly exceeded what, under the jiresent social conditions, is its normal amount. What may be maintained without hesitation is, that if there had been, as is often alleged, an increased production ■of insanity in the connnunity, the additional facilities furnished by the law for })ioviding asylum accommoilation in all jiarts of the country would have led to an increase in the ])roportion of the community detained as jiaujjer lunatics in asylums in ^Midlothian not less than •elsewhere. " It will be observed that in these )emarks only those j)auj)er lunatics have been dealt with who are inmates of e.stablishments, and that no 906 INTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. account has been taken of those resident in private dwellings. The reason for this is that, in dealing with the question of the prevalence of insanity in any portion of the community, there are certain advantages in restricting our consideration to those who require detention. One advantage is the fact that the persons dealt with are believed to require detention involves the inti'oduction of a practical element, which gives a degree of definiteness to their condition. The grounds which are held to justify a certiticate of lunacy must always be more or less arbitrarily determined ; but their arbitrary character is to some extent diminished when it is necessary at the same time to determine that the patient cannot be satisfactorily dealt with out of an asylum. The I'espon- sibilities and obligations which are involved in sending a patient to an asylum are calculated to exercise a steadying effect on the action of those who give the necessaiy certificates, and to inci^ease tlie soundness of statistics which are based upon them. " But, though the class of paupers in private dwellings who are dealt Avith as lunatics is perhaps more loosely defined than the class in asylums, a glance at their position in the county of Midlothian is both interesting and instructive. And here it may be well to allude to a misapprehension which seems sometimes to exist. It appears some- times to be supposed that the providing for pavqjer lunatics in private dwellings in Scotland is a result of recent administration. The fact is, that the number of persons provided for in this way does not bear so large a proportion to the population of the country now as it did when the present lunacy system came into operation. The number has indeed increased from 1877 in the year 1859 to 2140 in 1887 ; but this is more than 300 short of what would have been accounted for by the increased population of the country. " The position of pauj^er patients in private dwellings has, however, been altered in important respects by the administration of the Board. During the earlier years the eftbrts of the Board were directed mainly to the sending to asylums of patients who were unsuitable for treat- ment in private dwellings, and to the ameloriation of the condition of those who, though suitable for such treatment, were inadequately provided for. In pursuance of this coui'se, the number of pauper lunatics in private dwellings was considerably diminished. But it was presented from diminishing so much as it would otherwise have done by the fact that a large number of persons pi'eviously unreported, Avho were suitable for care in private dwellings, were during the same period brought under the supei-vision of the Board. It was recognised by the Board, from an early period of their administration, that the providing foi' a certain number of pauper lunatics in pri-\ate dwellings was one of the elements of a pi'oper system of lunacy administration. The Board have not, it will be seen, introduced a new mode of providing for pauper lunatics. They have only f'ndeavoured to place under pi-oper regulation a mode of provision which has always existed in Scotland, and which, indeed, has always existed in every country. The ditt'erence between the system which they have been enabled to establish and that of other countries, consists in the fact tliat the patients so provided for are under the supervision of a central authority, which re(|uires to be satisfied that they are suitable for such treatment, and that they will receive it in a satis- IIOUSIXG OF TIIK IN'SAXK I\ VICTORIA. 907 t':ictory iii.-inner ; while, in most otlier countries, those who are so provided for may be said to be merely left outside of the general lunacy administi'ation. "In order to understand fully the present position of the matter in Seotland, it is necessary howe\"er, to allude to another important change which has been brought about under the Board's administration. Tlie position of the patients has been altered in a way which is chietly indicated in the statistics of the Board, by the decrease m the number of patients i-esident with relatives, and the increase in the number resident with strangers. ^V few words are necessary to explain the significance of this change. The extent of the change is shown in the following statement : — ActiKiI Xniiiher of Panprr Lunatic' in I'riiatf Direllinrii Midlothian Scotlantl Midlotbiau Scotland \ IssT f I85;i i 18S7 With Kelatives. 64 4(i 148-2 !t72 Witli Sfcrangoif and Alone.* ISft 395 1U)8 Proportionf! per 100,0(10 of Population. 1859 1887 1859 1887 With Relatives. '24 11 49 25 With Strangers and Alone.* 12 44 13 30 . Totals. 96 232 1877 2140 Totals. 36 55 62 55 " As has been stated in the Keports of the Board, the decrease in the number of patients resident with relati^'es is not regarded as being in itself a desirable change. The view of the Board has always been that, where asylum treatment does not seem to l)e required, the patients should be enabled to live as much as possible " in a way little removed in its character from the mode of life which the}- would have led had they not suffered from insanity." + For this purpose it is obviously desirable that they should live with relatives, rather than with strangers. Two reasons have led to an increase in the number of those under the charge of strangers, and to a decrease in the number of those living with relatives. One reason is, that relatives are not so frequently Milling as they once wei*e, to undertake the care of the patients ; and another is, that it often happens that the relati^es Avho would receive them are unable, from unfitness either in tliemseh es or in their circum- stances, to furnish such treatment and accommodation as are necessary for the welfare of the patients. Tt is not given to exeiff one to have those personal qualities which are recjuired in a good guardian of the insane, and some who would, from family relationship, naturally be tlieir guardians, are specially deficient in such qualities. Many of the cases which, in the earlier years of the Board's administration, were the cause of difficulty and anxiety, were tho.se in wliich patients were * It is rarely, and only in very special circumstances, that a pauper lunatic is allowed to live alone. There have, however, l)een a few such cases, and these have heen tabulated along with those resident with >trangers. Their nuniher being so- small, it has been thought unnecessary to separate them. t Twenty-seventh Annual Eeport of the Board, page xii. ■^08 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. under the charge of incapable mothers, or other near relatives. Tt will be easily imderstood, that the amelioration of the condition of such patients while with their relatives is difficult, and often impossible, and the removal of the patients to other care, against the wish of the relatives is often found to be impracticable. A considerable number of such removals have however been effected. But tlie chief cause of the increase in tlie number of patients resident with strangers is, that the circumstances of their relatives often make it impossil^le for them to furnish the kind of accommodation and treatment which the patients require. This remark applies especially to the case of pauper lunatics belonging to urban parishes, and it is among these patients that the great proportion of those now resident with strangers are found. In urban districts, the majority of the relatives of pauper lunatics are found in the heart of great towns, and such localities are unsuitable for a lai-ge proportion of the patients. Due supervision, an adequate amount of open air and exercise, and the provision of suitable occupation cannot be obtained there ; and in such circumstances, the only alternatives are either to keep the patients in asylums, or to place tliem in sviitable localities with strangers." A general discussion by those present took place, resulting in the •condemnation of any huge system of cottage asylums being adopted, as has been foreshadowed by the Yictoiian Government, the plan most highly thought of being that of a combination of the block and cottage, ■with a detached hospital for acute cases where all appliances for treat- ment should be at hand. The boarding out of tlie harmless insane was approved of, but as a system, it was feared that the conditions of colonial life would militate against any marked success in such numbers -as to warrant the large expenditure which would certainly be necessary. Dr. Beattie Smith, in reply, remarked that he was pleased that his views had met with such general acceptation, and urged that a willing and energetic spirit be brought to bear on the subject of treatment in private dwellings for the poorer classes, as a means of relieving oui- overcrowding, if for nothing else; and that, although America had found it " impossible to secure reliable and proper persons to take charge of patients, except at an impracticable expense," Victoria ought to boldly «trike out for herself, and demonstrate her own capabilities or tlie revei'se in tliis dii-ection, so as to at once settle vipon a definite plan of future extension of accommodation. Tlie President, Dr. Manning, and several members of the Section, accompanied +)y the Hon. Secretary, A'isited the Metropolitan Asylum at Kew. After a careful inspection of the buildings, general arrange- ments, and gi'ounds, the opinion was openly expressed that the institu- tion had been markedly improved within the past few years, and I'etlected nothing but praise on the officers concerned. The separate building for idiots received a large share of attention, as the sy,stem of treatment therein is entirely a new feature in Australian asylums, tlie methods employed being a distinct advance on those used in any of tlie other colonies. Other memljers of Congress visited tlie asylums, and were pleased ■with tlieir reception and what they saw. SECTION OF PHAEMACOLOGY. PRESIDENT'S ADDRESS. By Barox Sill Ferdinand von Mlklleu, F.R.S., K.C.M.Ct., Pli.D. Govcrument Botanist of Victoria. Gentlemen, — Through the generous sentiments of the President and the Councillors of the Congress, it devolves on me now to open the pioceedings in the section for Pharmacology, or what may be regarded as equivalent for Therapeutics, Materia INIedica and Pharmacy unitedly, a highly honourable task indeed, on which however I enter with the greatest diffidence. Though in Pathology our knowledge be ever so accurate for diagnosis and prognosis of the characteristics and course of diseases ; though in Physiology our cognisance of vital processes be ever so intimate of normal conditions, and contrastingly of morbid changes, even if all this be ever so well supported by Chemistry and Microscopology in the minutest details ; though Surgery be ever so dexterous and experienced, guided by Anatomy even in most subtle particularities ; yet treatment may fail, if through Therapeutics cannot be brought to bear the most judicious selection of renaedies, and if through Pharmacy the genuineness and purity of medicinal substances cannot be secured. Therapy in its widest sense is constantly called into requisition by all other branches of applied medicine, to yield the weapons to be wielded for subduing human sufferings from whatever ailment. Through Therapeutics the treatment in most cases assumes its practical bearing, or at all events receives powerful aid for final curative accomplishment. Indeed, Medicine gains therewith mainly its expression of reality, and renders therewith culminating efforts. What the Aeneis said so long ago — Scire potestates herharuni usumque medendi, will indeed liold good for all times. Being taken back cursorily in our reflections to the dawning of our [)rofession, we may also here with veneration approach the founder, particularly in its pathologic aspects, of scientific medicine. Hij»pocrates, much more than 2000 years ago, employed already in a rational method some of the very remedies which even under the same designation still hold a place in therapeutic estimation at the present day ; the 910 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Hellebore, Mallow, Rue, Euphorbia, Soapwort, Sumach, Chio-Terebinth, Ai-istolochia, Pomegranate, Fennel, Chanioniile, Mint, Pennyroyal, Thyme, Iris and Squill were among his medicinal treasures ; and the Mvrtle, used by this descendant of the Asclepiades, seems to have offered to him already an antise})tic, closely akin to that of our Eucalyptus trees here. I will not detain you with explicit ol)servations on the much larger display of vegetable medicines used by Theophrastos, Dioskorides, Galenus, Pliuius and others among the leading ancient physicians, though many plants were ordered then as they are prescribed now ; and — what is fascinating to contemplate — thus stood the test of all ages. lu the able surgical address given by our honoured President at the Adelaide Congress, he pointed especially to the two greatest achieve- ments in recent advances of medicine — those of anjesthetic applications, and antiseptic treatments — both originating in the latter half of this century or nearly so, and both pertaining more jjarticularly to that branch of science, represented by the Section in which we are now assembled here. Indeed, only through these auxiliaries new courageous yet justifiable operations came within the range of possibility, and sui'gery could thus make the extraordinarily rapid strides during the last few decades towards its culminating development in the present day. Therapy, again, is indebted for this vast extension of its scope chiefly to organic chemistry and microscopic biology. AVhat a splendid co-o])eration of men of genius ! What a suljlime triumph of united mental force for the gTandest of worldly purposes ! For general medicine and almost equal in importance to the two agencies mentioned. Therapy has also yielded more lately— as you are all aware — chemical concentration, and therewith largely the means of hypodermic injection for multifarious administration ; these are two factors in pathologic calculations, to gain results of almost unerring exactitude. Perhaps I should not have alluded to all this, had we not to invoke these methods for novel experiments, to be instituted also here with Australian material. Armed with these i-equisites, we obtain facilities for watching effects, least disturbed by counteractions, on the living organism, and we are enabled to draw logical conclusions therefrom, applicable in professional exercise subsequently. Thus the questions will become gradually solved, how far each medicinal substance, chemically definable, affects the constituents, either singly or connectedly, of any particular organs of the living body, and how far morbid elements, invading or developed, would really be singled out, to be seized in each instance for restoration of normality. What chemistry thus has done in comparatively recent times for Therapy, may be instanced by two cardinal remedies, Ijoth undoubtedly PRESIDEXt's address — SECTION OF PHARMACOLOGY. 911 destined to hold a permanent place in medicine. From so unpromising a material as coal-tar, were not only evolved the uiisurpassably brilliant colours of aniline, and the marvellous saccha- rine (important already as a remedy in vesical affections), but it also , yielded phenol, one of the most powerful antiseptics, now universally applied in surgical and hygienic Therapy. Phenol again stands in close chemical relation to salicylic acid, in which we possess one of the best among recent offers to the materia medica, especially for internal use ; but both, in reality, are among the wondrous legacies from a former world of vegetation, which, though lifeless in its remnants, is rej)lete still with iucalculaV)le riches even for us in medicine. Etherisation began through American thought in 1846. Chloroforni, as another of the glorious gifts from chemical research, came into use almost simultaneously ; but Phenol, although isolated as long ago as 1834, by Runge, was rendered available for Phenolisation only in 1801, through the ingenuity of a British surgeon ; and Chloral, though among the earlier discoveries of Liebig, we know medicinally only since twenty years, so that many of us here have utiliseil these important aniesthetics, antiseptics antl hypnotics from the commencement. With vastly improved microscopic instruments, which 200 years ago would have charmed and amazed a medical worker in minutiis like Loeuvenhoek, were made those significant revelations particularly in our -days, through which so largely si)eciric forms of diseases could biologically be defined and evolutionarily traced. Although these startling observa- tions pertain mainly to the pathologic dominion of medicine, yet thereby also Therapy stepped into a new phase of its offerings, inasmuch as the great principle of inoculation can now be widely extended, but — let us hope — guardedly, to be always restricted within due bounds. The continuous application of the microscope is now-a-days also indispensable for therapeutic and pharmaceutic research, t(> study organologically and histologically the sources as well as the products and educts of j)lant-life and whatever else lies within the cyclus of therapeutics, not only for an accurate knowledge of what — thus far — we do possess in the materia medica, but also to lead us on comprehensively in rational comparisons to extended and independent researches, particularly so in a country almost new, like ours. Before I allude to what may most interest this distinguished assembly, to Australian data, some, I trust, of originality — it seems preferable to -single out a few of the most modern gains, which promise to be of permanency for therapeutics. The Cola-seed of Western Africa, although described by Caspar Bauhin fully 300 years ago, while he was Professor of Medicine in Basle, has only now entered into the materia medica; it allays thirst like Coca-leaves, and thus also should prove 912 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. acceptable to diabetic patients ; but like the Guaraua-PauUinia from South America, it affords also copiously Caffeine, and may therefore be entitled to notice for preparing a refreshing and mildly stimulating beverage ; indeed the Cola-paste, like that of Guarana, has recently become an article of commerce. The Pilocarpus may now be regarded as a fairly established and welcome acquisition, more so still as its active principles, an oil and an alkaloid, can readily be isolated ; the sialagogue action of the plant seems not yet sufficiently appreciated, and may point to some value in diphtheria. Strange to say, a similar property has lately been ascribed even to our ordinary garden tulip; while the lovely lil}' of the valley of our home-countries, which we easily could naturalise in forest-glens, claims also admission now, supported by high authorities, among them Dujardin-Beaumetz. Yet, as shown by Labbee and mentioned by the great therapeutist just named, Matthioli, the physician of the Emperor Maximilian II, more than 300 years ago, insisted already on its value as a cardiac sedative; while See and other physicians now place Convallaria next to Digitalis, with tlie advantage of being a comparatively harmless substitute, indicated as particularly eligible in mitral diseases with hydrops, its efficacy depending on two glucosides. As regards Melbourne literature, a brief reference to the Convallaria occurs already in the edition of 1885 of " Select Plants for Industrial Culture and Naturalisation." Let us lay stress on this resuscitation of one of the best known of all plants for medicine, to show how even the most valuable may sink undeservedly into oblivion. If Strophanthus should fulfil the expectations set on it as a cardiac tonic, then a clue would be given to the probable medicinal worth of a large sei'ies of other apocynaceous plants, some occurring also in this part of the world ; and the maxim, that natural affinity often indicates similar medicinal properties, would be brought to a further test. Quite in a different direction suddenly turns up a plant, as familiar to us as the tulip or lily of the valley, one from which we would least expect any utility for strictly medicinal purposes, namely, the Fagopyrum, because two practitioners in the United States, Dr. A. M. Duncan and subsequently Dr. P. S. Root, have demonstrated that the groats-grain of Fagopyrum in cake-form is safely available for diabetes-patients, notwithstanding the starchy but evidently peculiar contents of the grain, the use of which does not increase the glycosuria. Such a fact is again significant as showing how an article, familiar for centuries as a food, may escape therapeutic recognition for lengthened periods. Passing on to a different turn in our subject, we may ask, what future is before the Sulphonal 1 It was discovered and recently introduced by Professors Kast and Robbast, and subsequently more particularly by PUESIDKXT's address — SECTION OF PHAnMACOLOGV. 913 Professors Schwalbe, Guttmann and Otto as a hypnotic free of danger and signally effectual, when the agrypnia arises from purely nervous irritability, no unjileasant subsequent effects being observed; it is further claimed for this new remedy, that it produces a normal sleep, and acts even after long use of narcotics, is tasteless and devoid of odour, affects neither the digestive nor the respiratory organs, according to a connected i-eport by Dr. Nevinny. Should all this be attainable in a majority of cases only, almost a kind of panacea would be secured for an endless number of sufferers. The Sulphonal is a solid combination of sulphurous oxide, with a certain proportion of carbon. It seems preferable to either Amylene-hydrate or Paraldehyde, with an action more prolonged than that of hj'drate of chloral, and with this further advantage — so far as we are hitherto aware — of causing no subsequent functional impairments. Beyond the well recognised Amylene-hydrate and the Nitrite of Amyl, various other chemical compounds of the Amyl-series seem forthcoming for therapeutic purposes, some of a complexity, in the long array of their chemical symbols, that only a thoroughly niatheniatic mind can grasp their constitution ; but it is quite beyond the scope of this address to enter into particulars of this promising subject. But here it might suggestively l)e also asked, could not some other safe and controlltible means be devised, to lower the bodily temperature in all sorts of fever, and perhaps also in insomnia, such slight and cautious cooling to extend particularly towards the nervous centres. Curious as mildly sleep-inducing is even a pleasant fruit, that of the North-American Casimiroa, approaching in affinity to the Orange-tribe, but yet foreign to our tables. How for periods of great length the exact origin of some drugs may remain obscure, is exemplified by the Chinese Stai'-Anise ; for it was not many months ago, that Sir Joseph Hooker became enabled to identify and describe the particular lUicium (I. verum), which furnished during three centuries the star-anise, chiefly as a component of a cough-tea of great popularity, particularly used on the continent of Europe. It might reproachfully be asked, why with such a host of novel plants to experiment on, as we possess in Australia, no ampler records of their medicinal properties are extant. But for such purposes real facilities are solely afforded in hospital-practice, and even there only sparingly ; because practitioners are hardly justified in their ordinaiy calls to enter on trials of this kind, unless by preliminary tests on organisms, other than the human, a fair insight has been obtained of what may be expected from any altogether new remedies ; and even then, in experiments on higher vertebrata, conflicts may be encountered with some small part of the community, should vivisection require exceptionally to be resorted to. INIoreover such experiments are in their 2n 914 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. results but too often negative, and then rather discouraging. In one direction however wide progress has been made ; it is this : the diagnoses of 9000 species of flowering plants of the fifth continent l^ecame reliably fixed, whereby simultaneously a firm basis was gained for applied science in all its ramifications, to trace with every accuracy the vegetable products of Australia, including those for medical use, to their specific sources. Perhaps this is not much ; still it should be remembered, that our institutions all had to be built up in these young colonies by the present generation or the one just passed away. More perhaps might have been done, bvit individual life is too short for progressive science. What however thus far has been accomplished, may stimulate into extra efforts, which otherwise the practitioner in his almost restless life, or the academic teacher in his already onerous calling might not carry out connectedly nor extensively. But what an immensity of working material is placed before us also for therapeutics in a new continent, often with the charm of absolute novelty ! If we are — so far — much in arrear as early colonisers of a continent, of which however large portions are not yet even geographically opened up, instances like the following should be remembered, that even the highly powerful alkaloid Cytisin, first produced by Husemann and Marne from the seeds of the common Laburnum-tree of gardens any- where, has never yet entered any jiharmacopoeia, though in experiments with animals its formidable action on the spinal cord and peripheric motor-nerves was readily perceived, on incautious administration to the extent of paralysis, the muscular system however remaining unaffected. So it is also only through recent researches of Schmiedebei'g, that the medicinal similarity of the common Oleander — through its glucosid Neriin — to Digitalis became demonstrated ; and yet this handsome garden-bush was mentioned already as poisonous in the remotest records of antiquity. A commencement has however been made here. Thanks to the erudite aptitude displayed in therapeutics by Dr. Bancroft, both species of Duboisia, as you know, have, with some slight aid of my own, been physiologically investigated, of which enquiry advantage was promptly taken in ophthalmic surgery. Let me also remind you here, that one of the best kinds of Catechu can be i)repared from Australian wattle-bark. We shall listen with particular interest to the information, which will be offered by Dr. John Reid in regard to the active principle of an Australian Spurge. The small herbaceous Euphorbia Drummondi, here referred to, might almost be considered identical with the E. Chamaesyce from the countries at the Mediterranean Sea, one well known already to Dioskorides and Plinius, and specially referred to in their writings. A congeneric herb E. })ilulifera, which from the warmer regions of Asia has PKK8IDKNt",S ADDKKSS — SKCTION OF PlIAiniACOLOGY. 915 establislietl itself iu Eastern Austrulia as a weed, seems to be iiiqcli used as a domestic medicine in China; and, to judge from Australian experiences, has evidently a sedative action on the respiratory organs. having been particularly lauded in asthma. Thus a wide Held for en([uiry is opened among these kinds of plants, numbering over half a thousand sj)eeies, variously dispersed through the world, about twenty occurring iu Australia, one of tliem big and cactus-like in the remotest no)'th of Queensland. Without intending to anticipate discussion, T may briefly observe, that in the original analysis of the highly acrid " Eu])horl)ium " (obtained chiefly from North-African succulent shrubby species) as instituted by Brandes, and also in some few subsequent analyses, what may be the real effective constituent in the copious resinous com])ound could chemically not be isolated. Possibly an oily alkaloid may e.\ist in the milk-sap of Euphorbia, just as Lobelin in that of Lobelia. Flueckiger has shown the Euphorbon to be closely allied to Lactucerin or Lactucone. In all likelihood, a very similar princi})Ie pervades more or less the niilk-sa}) of all Euphorbias, accompanied b}' other modifying ingredients. It would be tiresome ]>eriiaps, to enter into many technicalities ; but this much I may be allowed to say, that four large orders of plants, mainly or almost enti)-ely Australian — the Goodeniacese, Myoporinee, Candolleaceae and Epacrideie, remain, as regards medicinal or even simply chemical experiments, almost untouched. Whether the bitter principle of some Goodeniacete is merely tonic, and whether the noxious properties of some Myoporinaj have therapeutic .significance, remains yet unascertained. .Special laboratory arrangements are needed, to work with advantage on subjects like these, for systematising from a physiologic jjoint of view, e.specially when on a new line of investigations we are really without any guidance whatever. The Bitterbark of Riverina and other tracts of East Australia, from Alstonia constricta, is locally very celebrated as a tonic, and even as efi'ectiial in ague; it was chemically examined in this City, quite independently of the researches of Hesse. Oil of Santalum, officinal only since some years, is obtainable in a remarkable proportion from the fragrant wood of the West-Australian Santalum cygnorum. Leguminosse— ordinarily the second largest of groups in the universal empire of plants— stand for the purposes of medicinal research next to Myrtaceie in importance, so far as Australia is concerned, but are in their display of qualities much more varied. Though they yield somt- plants of great moment for human sustenance and by far the largest portion of alimentary pasture-herbs, yet they include in their wide embrace also some of the most deadly, such as the Calabar-bean. The uninitiated would be lulled into security also here, were he to meet 2n 2 916 INTEKCOLONIAL MEDICAL COXGKESS OF AUSTRALASIA. some of the dangei"ous yet innocent looking members of the order. Erythrophlceum Guineense, one of the ordeal-trees of the wild and superstitious hordes of Western Africa, was shown l>y a Melbourne citizen, when he was in the field many years ago, to have almost its counter-part in an Australian tree of wide tropical distribution {E. Laboucherii), whereas quite lately the existence of a third species (E. Fordii) in South-China has been demonstrated. In this genus we have again an admirable example, how we can often argue from systematic affinity also on the utilitarian properties of plants. Thus the Erythrophlcein is likewise largely developed in the Australian tiee. According to Lewin, a local anaesthesia, extending occasionally to the length of two days, may be produced by it. Some melancholy interest attaches to our Erytlirophlreum, because it was the ill-fated Dr. Leichhardt, whose place of perishing is not even yet known, who through his first glorious expedition along the northern ])ortion of the Australian Continent, brought it as " Leguminous Ironbark-tree " under notice, not however suspecting its medicinal significance. Indeed, the clue to the virulence of these trees was given by the negi-oes, who employ their plant also to stupefy fish, just as the Antilleans do the bark of the medicinal Piscidia, the autochthones of North America branches of Gelsemium, and the Australian and some other nomads often sprigs of some Tephrosias and Tribulus for the same purpose. Abrus, even longer known than the Cola, became recognised in its seemingly unique importance only within this decade, first by De Wecker ; as a plant of all the tropics it extends also to Australia, where it was noticed already in 1699 by Dampier : its usefulness in Trachoma and Painius was proved also here by Mr. Rudall and other ophthalmic surgeons, notwithstanding some danger of atrophy of the conjunctiva possibly arising from the use of this seed, as pointed out particularly by Knapp and some other surgeons. If I rightly remember, Martius already alludes to some therapeutic power of the Abrus in his " Specimen Materia? Medica; Brasiliensis," published in 1824 soon after his return from South America. Sattler seems to have discovered a particular micro-organism, which has been sup- posed to set up the fermentive inflammation, by which it is sought to destroy the morbid layer. The use of Abrus-seed has latterly been suggested in the treatment of Epithelioma. Curious to record, the spores of PufF-balls have been recommeiided for the same pur- pose. I should forestall the learned and zealous honorary secretary of this Section of the Congress, were I to discuss, if even only pre- liminarily, the interesting data connected with the poison-shrubs of South-Western Australia, species of Gastrolobium and Oxylobiuin. Dr. Grant will bring before you the new observations, instituted I president's address — SECTION OF PHARMACOLOGY. 917 purposely by Dr. Rosselloty at tlie instance of Dr. Waylen, the Chief Medical Officer of Western Australia ; this will be all the more worthy of your attention, as the particular group of these simple-leaved harsji leguminous shrubs is restrictearatively recent PRESIDKXt's ADDKKSS — SECTIOX OF PIIAn.MACOLOGY. 923 clearer discernments, 1)\- usinj;' foliage from Leptosperniuni for an antiscorbutic Tea, given to the sick of the crew, while the great navigator stayed in New Zeahmd ; hence the popular name of "Tea- tree " also for so many Australian shrubs, even if not arborescent. It is a gratifying fact, that in this city pharmacists first strove to obtain for their profession that raised and lecognised status, of which it now can bo proud, a movement which from here soon extended to the other Australian Colonies. Here also they established their first college. A word of recognition must be given to the enterprising chemists and drug-merchants, who, as fellow-colonists of ours, have started factories of their own, the display from some of them at the Centennial Exhibition being magnificent. The now numeious pharma- ceutic societies all over the globe are within their own .sphere grandly advancing the intrinsic interests of their calling, as Pharmacy is bountl as a powerful auxiliary to keep pace with the quick advance- ment of medicine. Under sucli auspices, we can autici[)ate that the pharmaceutic gentlemen, while gradually scattering establishments of theirs over the whole Australian continent, will seize the splendid op})ortunities afforded them for such original researches, as can only be carried out in native fields. How would a Sonder, Rabenhorst, Kuetzing, Mitten and Boeckeler have rejoiced to win laurels on virgin .soil of continental ex|)anse, previously untrodden by civilised man ! Workers from their ranks must be inspired l)y the glorio\is achievements from the time of 8cheele and Chaptal to that of Oersted and Dumas, from that of (Tmelin and Hose to that of Flueckiger and Att field. It would be an incalculable l)Oon, if an intfsrnational pharmacopteia could authoritatively be established, with weights and measures of an uniform standard, doubtless finally everywhere according to the decimal system. But to avoid more readily the occurrence of numeric errors in the writing or interpretation of figures, it might be be.st in prescribing, to use distinct letter-designations for the decimal jn-oportions of grammes and litres, should these standards ever be adopted as universal. In the United States the re-issue of the Pharmacopoeia is decennial ; this acts as an incentive, to bring timely together all additional data, meanwhile gained, for .systematic and conforraous insertion. Not all Pharmacopa^ias are " up to the times" as regards phytographic nomenclature, so as to render it consonant with every recent discovery. Whoever had an opportunity of seeing the prescri[>tions, kept with a kind of sanctity as heirlooms in old family-shrines, even only from about 150 years ago, must have been astounded at the multiplicity of the ingredients constituting some of these extraordinary compositions, which were regarded as a sort of talisman in many a hou.sehold then. Never 924 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA, theless, some of the modes of cure in vogue about that time in many cases may have come undeservedly into disuse, for instance the copious internal administration of olive-oil against corrosive poisons. Quite rightly the newer turn in prescribing has been towards simplification, but not tliat thereby in any manner a leaning to particular doctrines is to be indicated. It may be difficult or even impossible, to follow up observingly the action of any medicinal substance in conjunction with other potent remedies, possibly antagonistic to each other physio- logically as well as chemically ; the effect then of each single coijiponent is apt to be lost sight of, nor can its action be fully con- trolled, even if our knowledge of the mutual relation of the ingredients were in each case perfect. J^ooking to the future, we must be afi-aid and therefore prepared, as maritime journeys are more and more shortening, to see sooner or later also epidemic diseases invading Australia, such as the deadly of eucalyptus, stating the same to cure ague. The pseudo-bulbs of an orchid (cymbidium) are used successfully at times by bushmen to check diarrhavi. Mr. C. Hedley states " Proc. Ivoy. Soc, Queensland," vol. \, part I, p. 12) : " If the pseudo-bulbs of cymbidium canaliculatum are grated up and boiled, a body is pi-oduced not to be distinguished from arrowroot. Delicate children have been i-eared on this, when accidents \\i\\e cut off from them other supplies." Two leguminous plants are well known as being poisonous to sheep, namely, (iastrolobium granditlorum (poison-bush), and Swainsona galegi- folia (Darling-Pea). Althougli these plants have been often examined, Ijoth in the colonies and in (Jennany, no poisonous princijile has ever l)een discovered in them. Already forty-five plants growing in the colony have acquired a reputation as being more or less poisoi\ous to stock. These plants, with several exceptions, are probaljly inert. Almost any plant, under certain conditions, will poison sheep. Erythrophkeum Laboucherii is said by Baron Von Mueller to contain erythrophkein, the active principle of E. Guineense. The gum of Acacia Cunninghamii makes a good adhesive mucilage; it is, however, dark in colour. Tlie pods of an acacia growing in the Gulf of Carpentaria district are rich in saponin. Mr. Bailey is of opinion that this is the acacia named by A. Cunningham " Acacia delibrata." 20 930 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Xantlioxyluin veneficum (Bailey), a small tree, lather uncommon even where I discovered it growing on the Johnstone river, contains an exceedingly poisonous principle, which however has not yet been separated. It appears not to be an alkaloid. Tlie action it causes, wlien injected into warm-blooded animals, seems much like that of strychnine; yet upon frogs, it does not cause tetanus. A particle of an alcoholic extract of the bark will, if placed upon a frog's back, cause great excitement — the frog jumps violently about until it becomes, in ;i fev/ minutes, liaccid. When first I examined this poison, I erroneously .supposed the excitement to be tetanus. The genus Daphnandra, of the order Monimiaceee, is very interesting, as possessing several alkaloids of a stable and crystalline nature. In their physiological action, they resemble somewhat the Digitalis grouj). I have for some years now occasionally used a tincture of the bark of Daphnandra micrantha in the treatment of heart eases, apparently with good results ; my patients expressed themselves as feeling much better, and the sphygmograph showed some improvement in the condition of the pulse. Daphnandra kills frogs by its action upon the heart, and kills warm-blooded animals by its paralysing effect upon the spinal cord. Although I did not anticipate tliat any good would result fi'om the use of any substance having a paralysing action upon the cord, in the treatment of tetanus, yet I ti'ied Daphnandra in a severe case of tetanus in a man. He derived no benefit therefrom, and the last two days of his life he was kept, at his own desire, vuider the influence of chloroform. Should a remedy ever be discovered for tetanus, I believe it will be a substance having an injurious effect upon the microbes that cause the disease, like the effect of salicine in rheumatic fever, and quinine in ague. The genus of Laportea, tree nettles or stinging trees, so common in the jungles all over Queensland, has some interest to pharmacologists, inasmuch as after being nettled, one is reminded of the fact for several days, and in exceptional cases for weeks, whenever the nettled part is wet. Upon touching watei', there is produced a sudden severe pain, it is only momentary however. If the hand be the pai't nettled, the secondary pain starts in the spot nettled, and runs up the arm and down the corresponding side. No explanation has ever, as far as I am aware, been given to account for the secondary pain. A juice made by pounding the green leaves in a mortar gave no decided reaction with litmus paper ; it was tasteless, and when injected into frogs, had no action upon them. If the stinging hairs be carefully examined, and the tops shaved off with a razor, a few will be seen to contain a minute quantity of fluid, so small a speck is it however, that even with the microscojje it is impossible to test its reaction with litmus. The juice of Colocasia macrorrhiza plays the part of the dock in England as a remedy for application to parts nettled ; it however seems quite useless. Tli<; adage, "If you gently toucli a nettle, it will sting you for your pains," is not applicable to tree nettles, for in order to be stung, it is necessary to Iiandle the leaves roughly, or brush against them with some force. The fracture of the points of the stinging hairs is quit<' audible, and one feels a prick when the point enters the skin ; in a second or two afterwards, lie is conscious of having been nettled. POISONOUS ACTION OF OASTUOLOlilUM AND OXYLOBIUM. 931 T um indebted to my friend, Mr. F. 3r. J5;iiley, for Iiis kindness in phicing in my huuds specimens of the two native species of Stryelmos, viz., Stryelmos psilosperma and Stryelmos lucida. All pai'ts of S. p.silo.sperma are bitter, but not so bitter as strychnine. 1 was unable to kill tVogs with this plant. S. lucida is, on the other hand, extremely bitter. So intensely and persistently bitter is this plant, that one would imagine that it was very rich in strychnin<>. 1 was astonished, howevei", to tind that I could not tetanise frogs with it. It was not even poisonous to them. The frogs used, '' Hyla ccerulea," are very susceptible to strychnine. I had only one fruit and se\eral leaves — too small a quantity to attempt any chemical analysis. There are many other plants interesting pharmacologically, among which may be mentioned the genera — Piper, Flindei'sia, Archidendron, Harpullia, Pongamia, .Marlea, and Xanthiunu 1 NOTES OX THE POISONOUS ACTION OF SPECIES OF (TASTRr>LoBlU.M AND OXYLoBlUM. By Dr. IiOSskllotv, AViliiams Ki\er, Western Australia. The plants reported on are kno\\n loctilly as (1) Heart-leaf Poison, (2) York Road Poison, (3) Narrow-leaf Poison, (+) Bloom Poison, (5) Box Poison. From the .specimens sent. Baron Von Miiller has identified them as (1) Gast. bilobuni, (2) O. calycinum (Benth.), (3) a G. allied to G. oxylobioides and G. microcarpum, (4) (r. ovalifolium, (5) Oxylobium parviflorum (Benth.) All of these plants have a powerful narcotic action, and it is a valuable result that the species G. Ov(difolmiii, not pre^•iously recognised as poisonous, is now known to be so. The symptoms are as follow^s : — (1) Bo.c Poitsoii (Oxijhjhiitia ijarvljiorum). — More virulent than York Road poison, but being tallei- in growth, is not so much eaten by sheejj except when in bloom, when they seek it, and it is \ery fatal. Effect Oil Sheep. -Does not show its eftects for from eight oi- ten hours after eating it. They then seem to go blind, run about nuich, and fall on tlie ground in strong convulsions. They generally ha\'e three tits befoi'e they die. Post-mortem appearances. — Heart goi-ged with blood almost to bursting. Lungs not so much congested as with York Road. iStomach and liver also nuich congested. Dogs eating the flesh have similar convulsions, and bite anyone they come near. Pigeons and other birds eat the seeds of all the poison-plants with impunity, Init their entrails will poison cats or dogs, but not the flesh." (2) York lioad Poison {Gicstrolobium calycinnm, Benth.)— It tak«'s effect on sheep within six hours of eating it. Convulsions come on in twelve hours. Sheep jump about, and muscles contract much. It seems to pre\cnt both sheep and cattle from chewing the cud, by 2o 2 932 INTEKCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. affecting the first stoiuacli. If the stomach is full Ijefore eating the poison, there is less chance of recovery. In the fir.st stage, salt seems to be an antidote, causing them to chew tiie cud. Post-mortem apjiedr- ances. — General congestion of the lungs and stomach. Inner coat of stomach easily peels off". It affects cattle similarly to sheep. Horses are affected by trembling of the muscles, loss of muscular power, swollen and di'ooping eyelids. Convulsions not noticed in them. The poisoned carcases, if eaten. by dogs, do not affect them so much as those of animals who have died from box poison. (3) Heart-leaf Poison ((/. bilobum). — The effects on sheej) are sleepiness and drowsiness. Acts in about the same time as box poison. Almost harmless except when in bloom or seed. .Sheep eating it then seldom recover. Lambs die in about six hours. Post-mortem appearances. — Stomach and intestines, liver and lungs, much congested. It seems to prevent urination and defiecation. Paralysis before death. (4) Bloom Poison (G. ovalifolmm). — Exactly same effects. (5) yarrow-leaf Poison. — Being less in qv;antity in tliese parts, has not been much observed. [From these few notes, it is of course impossible to determine the exact physiological action of these poisons, Ijut it is sufficiently evident that they all act very energetically on the ner%e centres. Two of them, viz., Box Poison and York Road Poison, appear to be mainly convulsant ill their action, producing symptoms somewhat similar to those caused by spinal irritants ; while the other two. Heart-leaf Poison and Bloom Poison, seem to have a paralysing action on both brain and spinal coi'd, producing drowsiness, inability to evacuate bladder and bowels, and motor paralysis. And it is notable, that the former two are I'espec- tively a Gastrolohium and an Oxylohiuin, while the two latter both belong to the genus Gastrolohium, so that tlie difference in physiological action does not correspond to generic distinction. Thei'e are several points of special interest in the symptoms produced. (1) The length of time (six hours and upwards) which elapses before tlie advent of symptoms. (2) The alleged effect of Box Poison in producing blindness in sheep. This may be compared with the similar action of a blue- flowering Grass-Lily, growing in the same district. It is useless to speculate as to its exact mode of production, but probably it may be due to a special selective action on the visual centre. (3) The poisonous action on dogs of the flesh of poisoned animals, causing, in the case of Box Poison, convulsions similar to those of the poisoned sheep. (4) The immunity possessed by pigeons and other birds eating tlie .seeds of all the poison plants, while? their "entrails," but not tlieir flesh, are poisonous. This reminds us of tlie very great tolerance of opium and morphia in tlie same animals. (5) The observation that Gastrolohium ovalifoUum (Bloom Poison) is also poisonous, a fact hitherto unknown to botanists. It is to be hoiked that all these plants will be made the subject of precise experimental investigation ))y pharmacologists, for it is probable that poisons acting so powerfully on the nerve-centres will Ite found to possess valuable therapeutical properties. — D. G.J J BISMUTH : ITS PK015ABLE THERAPEUTIC POSITION. 933 BISMUTH : A CONSIDERATION OF ITS PROBABLE THERAPEUTIC POSITION. By Thomas Dixsox, M.B., CM. Edin. Considering the extreme fretiiienoy of the use of this metalloid in its many forms, and its undoiiljted value, it is astonishing to find how various the theories of its action are, how little these help us in deciding when to use it, and finally, how little of wliat is really known is given in the leading text books in Britain. I have, pei'sonally, long had doubts as to the validity and utility of the accepted theories in currency ten years ago, viz., tliat bismuth trisnitrate acted as a coating powder. A much-used modern text book (Bruce) desci'ibes its action as sedative and astringent; wliile the best description pi-obably is that of the epoch-making text book of Lauder Brunton, to which we will refer presently. The value of a theory is of course, at any time, to be estimated by its helping us to form deductions which, when applied, lead to satis- factory, or at any rate foreseen results. The less often these results tally with our deductions, the less the value of the theory. Now, it is not by any means a matter of indifference in the case of bismuth what our theory may be, for, thanks to the " mechanical coating " theory, several instances of poisoning have occurred, in some cases resulting fatally. As regards the indefinite description, " that bismuth acts as a sedative and asti'ingent,"' one can make but little use of it. If we use such terms, we must understand what is meant. Does bismuth act like the typical sedfitive opium, or as the typical astringent tannic acid and the salts of the metals '? If we merely imi^ly that it acts by lessening pain in some unknown way, we could class the use of a blister in pleurisy under "sedatives;" or that it lessened diarrhrea, we could class anti- septics under the heading "astringents." Such a use of terms is _too loose to do anything but mischief, unless most carefully defined. "We will discuss the theories now more minutely : — (1) The "mechanical theory," as it maybe called, states that the powder formed in making the basic salts, the carbonate, and the oxide, itc, distribute themselves when taken by mouth uniformly over the stomach and intestines. Can any one conceive twenty or thirty grains of a heavy powder coating tlie extensive surface of the human stomacli, especially when this again is covered with a coating of nuicus- a body which becomes more tenacious in inflannuatory states? The difficulty of maintaining this theory is the greater when we remember tliat bismuth powders rather by their weight tend to fall to the bottom of a cavity, and that the powder is composed of crystals. Were we dealing with mica, which forms ''smooth" powdei-s, we might have some ground for using this theory pei-haps: it is inert too, and would be suitable. (2) To compare bisnuith with charcoal, as Brunton does, is not helping us much, considf-ring there are even several theories as to the action of charcoal, and that chai-coal is a bulky, gritty, chemically unacted-upon substance, of great chemical power, best sliown when it is freshly burnt, and only perliaps of medical value under similar circum- 934 INTERCOLONIAL MEDICAL CONUKESS OF AUS TKALASIA. stances ; iu other woi-ds, a body whose action is not understood, a Ijody as unlike bismuth, physically and chemically, as need be; and finally, a body with no clear therapeutic affinity to it whatever. (3) >Schmiedeberg"s theory suggests that as bismuth basic salts readily assume tlie neutral form in presence of acids by dissolving in them, we liave tlie slow characteristic action of astringency (seen in metallic salts), by which, in presence of albumen, the salt splits up the acid and base, uniting with the albumen, and so forming precipitates. This theory is not easy to disprove for the case of the stomach, but is evidently unsuitable for explaining its influence in diarrhtea, for the basic nitrate (say) would be the natural form of tlie salt so soon as it got to the alkaline parts of the intestine ; in fact, very soon after leaving the stomach. This theory, therefore, is insufficient. (4) The arsenoid action. This action has long been mooted, then cast aside and forgotten, till recently in Britain it is very hesitatingly and unsatisfactorily given by Brunton, who drojjs it for the one above. Let us hear what he says in the third Edition of his work: — "Tlie soluble salts of bismuth, such as the citrate of bismuth and ammonium, when given in large doses (how ?), have an action like that of antimony or arsenic, and cause gastro-enteritis, witli fatty degeneration of tlie liver. Small doses of the soluble preparations, or larger doses of sparingly soluble preparations, have a sedative effect upon tlie stomach, like that of minute doses of arsenic. The subnitrate is so sparingly soluble in water, that its utility in gastric catarrli is probably due to its mechanical action, like charcoal or binoxide of manganese. The carbonate is more soluble in the gastric juice than the subnitrate, and is supposed to be more powerful, and the same is true of citrate of bismuth and ammonium. My own experience leads me to prefer tlie less soluble subnitrate to either of the otlier pi-eparations." A resume of his further information is the following : — '' The dose of the insoluble preparations is given as 5-20 grains, while the soluble are given as 2-4 grains. He says, that the soluble bismuth and NH.. salt is more astringent and irritant than tlie insoluble salts, and is inferior to the latter in allaying irritation." 8uch is the essence of what our best British autliority gi^■es us. The information lie gives is fragmentary perhaps, yet it is decidedly a long .step towards the view now more accepted in France perhaps, than in Britain, that bismuth is essentially, pharma- cologically, a member of the arsenic family, and towards the view I advocate " that its actions, therapeutically, are dependent essentially upon this affinity,'' a view 1 have for some years taught. In discussing bismuth, it is therefore our duty to see how far it agrees with the other members of its group, and then what moditica- tions of action characteristic of itself are distingyishable ; for though ai'senic and antimony essentially are related, they neA^ei'theless have their differences ; these differences are modifications or tones rather than real differences, and the differences lietween bismuth and antimony we will see are of a similar nature. Let me first consider the chemical rehitionshi]> of these bodies, for it gives the chief clue to our question. We have N., P., As., Sb., and Bi. (Vd. has not been studied pharmacologically, and need not be discussed here). BISMUTH : ITS ntOKAULK TIIRKAPEUTIC POSITIOX. 935 "We Hud that as we rise in tlie series, the oxygen compounds l)econie less and less acid, and more and more basic, also more and more stable ; there is a vast difference between NoO., and BioOg. To this oxidising power, Binz ascribes the action of the gi'oup pharmacologically. As i-egards the salts of these metals, we notice that arsenic is a feeble Ijase, antimony a stronger, and bismuth the strongest ; that Sb. and Bi. form salts which, thrown into great excess of water, yield oxy-salts, which are insolulile in watei-, but more or less soluble in acid solutions. iUit tJiese Ixxlies readily enough can be got to form a kind of double salts sucli as tartarated antimony, by combining with an organic acid and an alkali, e.r/., sodiocitrate of bismuth. PhxtrmacoloijicaU;/ then, w<» have the oxides of the group becoming hss caudic from N. to Bi. ; tliey lessen metabolism, and as a consequence, ap2:)arently lower the ner\e sensil)ility and retlex irrital)ility, depress the heart and circulation, and after each of them, we find fatty degenera- tion of the livei', etc. In all tliese points we find a striking resemblance, in which bismuth shai'es to the full, pro\ided it be got into the system, and it can be got into the system by injecting into the blood, or hypodermically, the sodiocitrate ; this salt, of course, having as such no other intrinsic action such as the NHg and Bi salt might liave. Therapeutically, we tind that arsenic and bismuth are used for some- what similar conditions, and antimony is a sort of bridge between the two. Arsenic is used well diluted, and in very minute doses J^ grain (say) for painful affections of the stomach ; to get its effect, it is best given before meals. Bismuth is given for the same. In lientei'ic iliarrluea they both may be given similai'ly, and even in ordinary diarrhoea some speak of arsenic being of value, while undoubtedly bismuth is often exceedingly useful, but in what doses 1 very large ones. In affections of mucous membranes more remote, we give arsenic, e.g., phthisis, conjunctivitis, itc, in larger doses for this purpose. Anti- mony is less used, except where we wish to produce the reflex effect upon the bronchi from irritation of the stomach — an action which we will tind even arsenic can produce, and bismuth itself still Ijetter. The latter is never employed for its influence upon, say the conjuT\cti\a, simply because no one has thought of it. I may suggest that it certainly would be hard to ol)tain, but is (juite possible fi'om my theory. Upon the skin diseases, we know how phosphorus and arsenic can act. Antimony has not been so much used, but bismuth is thought very highly of, applied externally — the only way to get it to the part. Upon the nervous system, P. and As. have been found to have somewhat similar indications. Theoretically, this treatment of local (not too diffuse) aftections of the skin by this group ought to l>e the best, inasmuch as the remedy is aj;)plied directly to the part. The remedy acts slowly and persistently, and has not injured the system before getting to the pai-t attiected. Where the local aflection is due to a constitutional diathesis, of course arsenic oi- phosphorus would be the best to give. Before I continue, I must remind you that, of course, bisnnith has uften other bodies present in it, but it is extremely pi-ol)al)le that many troubles due to bismuth lia\ e lieen ascribable to the presence of ansenic (n- lead, so often contaminating it in earlier days. The essential actions of bismuth have been elicited witli chemically tested pure si)ecimens. 936 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Comparing Sb. and Bi. we tind the resemblance clearer than evei'. Sb. is not SO absorbable; Bi. is still less so. If we apply tlie chloride, &c. of Sb. to the tissues, it is a caustic — a corrosive irritant; the eori'esponding bismuth salts are so too. This is due to the action of th<' easily detached acid of course. But give the tartarated antimony by mouth, and we get certain symptoms ending in emesis. We find that the sodio or ammoniocitrate of bismuth acts in the same way. In fact, the former has received the name of "bismuth emetic" (like our "tartar emetic"). Its action corresponds dose for dose with the Sb. salt. Now this is one direction where we, specially in Britain, have missed our mark, and explains wliy citrate of bismuth and ammonia is a misunderstood body. Here we need only allow ourselves to be led by our knowledge of the antimony salt, and all would be simpler. The dose of four grains seems simply far too large. It is hard to see, indeed, how it is tolerable at all in such doses in the system, and I cannot help tliinking tliat there must be many cases of slow poisoning (I do not say death) unrecorded, where tJiis absorbable salt was alone to blame. Of course, why As. and Sb. and Bi. say in minute doses in the stomach are sedative, and in large, irritant, we need not here discuss; but this apparently irritant and very extraordinary action on the part of our "sedative" bismuth is quite clear directly we remember its family relations, and prepares us for the subniti'ate having the same. And is bismuth trisnitrate really unabsorbed ? Well I know of no experiments where there were given by the mouth small doses of the annnoniocitrate (and this salt could be easily worked with), but contrary to the tendency of the theory, I may say that we have two important facts — first, that while we cannot produce constitutional poisoning by giving the trisnitrate, no matter how lai-ge tlie dose given to animals, even Ortila proved that bismuth appeared in tlie urine (liver, spleen, Arc. ) of animals, and the same has been found with man. And fui-ther, when applied as a dressing to wounds several deaths have occurred, showingtlie characteristic signs of bismuth poisoning; as a soothing inert insoluble powder acting by forming a sheathing, the bismuth could not possibly poison ; but if we drop this theoryandrememberthat a very .small amount absorbed of any member of this group will produce toxic signs, and that bismuth can be absorbed under conditions not fully understood, we at once are on our guard ; so too Bricka and Lyirbal and Lazonsky have found bismuth in various secretions. To understand bismuth, whetlier used for the intestines or the skin, as compared with As. (as the type), we must think of iodine and iodoform and iodol. The cliief active liody in each of tliese is the iodine ; yet for say an ulcei', the iodoform is incomparably better than iodine, for the first would simply exei't its action with, I might say, explosive energy : the latter giving of its iodine slowly and persistently, aftbrds the same influence that the continuous slow evolution say of iodine vapor miglit have — gentle, yet firm in action. Now, bismuth trisnitrate is really, as seen by its appearance in the urine, slowly given oft" in the intestine in a soluble form (not yet understood), jierhaps never in sufficient amount to be poisonous to the system, yet from the very potency of the members of tlie series, (piite sufficiently to exert ;i powerful effect locally. A \OTB ON DRUMINE: IS TIIKHK SUCH A BODY? 937 The bulk of a bisnuith salt becomes combined with the Ho8 in tlie intestine, and appears as tlie sulpliide, this fact explaining,' why tlie bismuth does not get into tlie Ijody in quantity sufficient to cause tlie symptoms of poisoning, whicli are very striking, in so far as they differ from the other members of the group, by one set of appearances, viz., blackening with ulceration. We could in fact imagine that we had a case of As. poisoning, witli strange blackening of those parts of the intestinal canal wliere H„1S is given off. We have the nausea, vomiting, diarrhcca with tenesnuis, uncei'tain movements, tetanic spasms, emaciation, albuminuria, granular casts, and death in paralysis ; but there is stomatitis, with swelling and ulceration of the mouth, as well as of the colon. The blackening is seen best at the edge of the gums and in the colon, and ends readily in ulceration. The explanatioii is simply this : — Bismuth, coming fi'om the blood, meets the sulphuretted hydrogen, which has permeated slightly into the tissues, and becomes deposited as B.^Sj in the capillaries, blocking them, and so causing necrosis and ulcers. In acute poisoning we see, as in As., clonic and tonic spasms, ending in deatli in a spasm, the blood pressure falling through paralysis of the centres for the vascular nerves, and through weakening of the heart's action (paralysis of the motor ganglia in the heart). Where are we to place the citrate, carbonate, and oxide of bismuth '? Well, these would be e\en more soluble in the acid of the stomach tlian the subnitrate ; this acidity, we know, is very variable, especially intense in catarrhal states, and thus we get an extremely uncertain energy of these salts. The trisnitrate is more suitable therefore, simply as being less soluble, or it may be better to use a substance which is not dependent at all on the factor of acidity, viz.. As. ; we give our dose of this, and can graduate it witli certainty. When we wish to treat intestinal affections, we must choose a body which will get to the intestine, and hence bismuth trisnitrate is preferable. Tii the stomach, the trisnitrate is dissolved probably by the acid ; and in the intestine, probably by the alkaline salts forming double salts. From this we can see tliat, especially in the stomach, we nmst be prepared for the subnitrate even showing irritant symptoms through dissolving in excess in the acid of the stomach, and so getting into an active state. I think then, we may deduce that bismuth is "arsenic with its wings clipped ; " that where arsenic can be used, it is better to use it, as being far easier to graduate the dose of ; but when we Avisli the arsenical effect to be continuous, or we wish it to get the arsenical effect in the intestine, bismuth will supply the desideratum best. A NOTE ON DRUMINE: IS THERE SUCH A BODY? By Thomas Dixsox, M.B., CM. Edin. Euphorbia Drlmmoxdii. In seeking the answer to the question of the existence of an alkaloid in the above, I may state that tlie plant was sent me l^y .^Ir. Bauerley, the well-known collector, and was thus genuine. 938 INTERCOLONIAL MEDICAL CONGRESS OF AUSTHALASIA. The first experiment of injecting hyi)oclermici\lly a large quantity of a strong solution of the carefully dried and filtered extract of the herb, with about 60 per cent, absolute alcohol and water, was negative in the case of the frog and guinea pig. In seeking signs of an alkaloid, I took an infusion of four ounces of the herb, obtained by weakly acidulating the water with acetic acid. This was filtered from the herb next morning, and treated with neutral acetate of lead, and then, after filtering, with basic acetate. The pre- cipitates were washed, and then carefully had their lead removed by sulphuretted hydrogen. This was done to the original filtrate also. All the fluids were carefully dried at a low temperature of about 150", but in no case did the solutions give any trace of an alkaloid with phospho- niolybdic acid, &:c. Finally, the search was made for drumine, as isolated by Dr. Reid. He suggested, in his pai)er in the Australasian Medical Gazette, to extract the plant with a weak acid solution. This I did ; then filtered, pre- cipitated with ammoniii, washed the precipitate with weak ammonia water ; re-dissolved it in weak hydrochloric acid, passed the solution through charcoal, and thus obtained a clear colourless fluid. Ammonia added produced a co})ious flocculent precipitate, which was filtered from the fluid, and carefully dried. Examined microscopically, it showed crystals according with Dr. Reid's description closely. Some were placed on a platinum pan; it darkened considerably, but left after heating in a red heat, a large amount of a white ash, soluble in HCl. The original powder was soluble in strong hydrochloric acid, not in acetic acid, and effervesced without blackening with Hg SO4, leaving a white precipitate. I could not find that watery alcohol, chloroform, or ether dissolved it at all. though of course hydrochloric acid did. Thus the substance was chiefly oxalate of lime, po.s.sibly only that body. I did not trouble to see if part of it were phosphate of lime, as the question was as to the j^resence of drumine. ON THE DOSAGE OF IODIDE OF POTASSIUM, WITH ESPECIAL REFEPvENCE TO THE TREATMENT OF PSORIASIS. By William M. Steniiouse, M.D., CM. Glas. Honorary Physician, Dunedin Hospital. In the Jlrifis/i Medical Journal of January 7, 1888, there appeared a. leading article on the treatment of jisoriasis by heioic doses of iodide of potassium, as recommended by the Norwegian physicians. Dr. Greve and Dr. O. Boeck, and carried into exhaustive trial by Dr. Haslund. When this article came under my notice, it so happened that I was treating a case of inveterate and very chronic psoriasis, with but iuditferent success. It is true that the affection yielded readily to local treatment, especially to the ap[»lication of chrysoi)hauic acid, but no ox THK DOSAGE OF IODIDE OF POTASSIUjM. 939' soonei' was the treatment suspeiuleil, than the tliscase returned in all its virulence. The internal exhiliition of drugs appeared after a year's patient trial to exercise no influence whatever upon the disease, although arsenic, tar, iodide of potassium, chrysoplianic acid, iodoform, and sulphide of calcium had all been put to a fair trial — the arsenic itself lieing pushed to the extreme limit of toleration. Of all these drugs, the potassium salt alone was thought to have had some controlling effect, although this was difKcult to decide, local treatment having been carried on simidtaneously. But theie was no doubt about this fact, that the iodide had relieved my ])atient of dyspeptic symptoms from which she had long suffered, and which are so often associated with psoriasis. The largest dose administered was thirty grains a day in ten-grain doses. Having lead the article in question, in which doses of from thirty to- fifty grammes in a day were said to have been administered successfully, it occurred to me that the case I was then treating was a favoural)le one for testing the curative power of the drug when given in enormous (loses, and the tolerance of the human subject for such doses. ]n view of the warning contained in the last sentence of the editorial, I determined to proceed warily, and not to begin the treatment until I had fully explained to the patient and her father the enormous doses I proposed to prescribe, and the inconveniences and risks the treatment would entail. Both the young lady and her father agreed to leave the case in my hands, and it only remained for me to carry out the- treatment so as to subject my patient to as little danger as possible. Here it may be as well to explain that the patient was twenty years old. and had suffered from general psoriasis — the face and head alone escaping — of a severe tyj)e since her fourth or fifth year, and that she had been frequently under severe and prolonged treatment without receiving permanent relief. 81ie was of a full habit, and with excellent general health, her only comjjlaint being slight dyspeptic troubles, and she had also a marked tendency to coryza. The plan I adopted was to Ijegin with a moderate dose and increase it gi'adually week by week until the disease was found to yield to the- remedy, or the limit of my patient's tolerance of the drug was reached. Accordingly on March 8, 1888, she began to take thirty grains three times a day. On the 2-lrth 1 saw her next, and found that she was able to take the- do.se with perfect freedom, and accordingly it was increased to sixty grains three times a day. I .saw her next on April 5, and now I found a considerable change in her condition. The psoriasis was untouched, but her j)ulse had become veiy rapid, 120 in repose, and nnich faster after a little exertion, and .she had lost flesh to the extent of seven or eight pounds at least. She also comi)lained that her strength was gone, and that she had no inclination to do anything but only to rest. There was no headache, no coryza, no conjunctivitis, and on the other hand she had lost her dyspepsia. As she was still willing to persevere, I resolved to continue the same dose of iodide, 120 grains per diem, but to add to each dose five grains- of tartarated iron, and three minims of tincture of strophanthus, and I also enjoined her to confine herself to the sofa. I did not .see her again till April 23, but had frequently heard of her in the interval as going on all right. On this visit, I found she was more tolerant of the drug than "940 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. she had been. Her juilse was still quick and frequent, sjiiall and soft, showing an absence of arterial tension, but it only counted 100 as com- pared with 120 on my former visit. There was no further falling off' in flesh, although she had lost a good deal of her normal stoutness, with which effect she was very well pleased, and she did not complain so much of want of strength. On inquiry, it was found that the drug had ^exercised no influence on her uterine functions, which were going on regularly. Her appetite also remained good, and she was quite free from dyspepsia. The dose she was now taking was 150 grains three times a day, which I told her to increase to ISO grains, which she was the more inclined to do, as the disease was visibly yielding. On May lo, the dose was increased to 210 grains three times a day. I then saw her on the 19th, and found her quite tolerant of the medicine, and greatly improved in respect of the psoriasis, which was fast dis- appearing. To continue the same dose till my next visit. Saw her again on June 2, found her still improving, although she felt weak and little inclined for exei-tion. To continue the same dose until the skin was quite clean. 8aw her again on June 13, and found her Avell. The only trace of the affection was to be found on the knees and elbows, on which were still a few thin scales. The skin of the rest of the limbs and the body was soft and white. I now resolved to reduce the dose in the ■same manner as it was increased, but more rapidly. I therefore now ordered 150 grains three times a day, and at the same time prescribed an ointment of iodide of potassium and lanolin, in the proportion of one part of the former to four of the latter, with which she was instructed to inunctuate her knees and ell)ows. On June 28, the dose was still further diminished, the whole of her body being now entirely free from her reluctant foe. On July 16, the dose was down to ninety grains three times a day, tlie patient keeping fi'ee from disease. On August 3, the drug was discontinued, there being still a trace of the disease on the elbows and knees. On August 23, I saw her again, and found indications of a return of the psoriasis. She expressed lierself as feeling better than she had done for years, having lost all her dyspepsia, and her tendency to corpulence. Her pulse was 70, strong and equable; both sounds of the heart clear -and full, and she expressed herself as feeling e(jual to any exertion. The whole quantity of the iodide used between March 8 and August 3 amounted to 100 ounces. Its influence over the psoriasis did not appeal- until the dose reached 360 grains daily, in three doses of 120 grains each. Thereafter, the disease rapidly disappeared. The importance of the case seems to lie more in the largeness of the doses employed, than in the ultimate effects of the treatment. The ^fleets of the treatment |)roved that iodide of i)otassium in excessive doses succeeded where ordinary medicinal doses had entirely failed. It Also proved that such doses can be administered with safety, although not without considerable inconvenience, as it was quite impossible for my [)atient, when the dose had reached 120 grains a day, to use any •exertion. It would therefore seem that, in enqjloying the drug thus lieroically, it will be necessary to enjoin strict caution upon our patients, confining them to their room, and as much as possible to a horizontal Attitude. Also, owing to the marked effect of the largest doses in weakening the action of the heart, and in producing an anaemic condition TriE EFFICACY OF CHI.W TIIIPEXTIVE IX CAXCEH. 941 of the blood, the exliibition along with the iodide of some heart tonic,, as digitalis, stvophanthus, or couvallaria, with iron, would seem to be- indicated. In the case now under notice, the administration of five grains of tnrtarated iron and five minims of tincture of stro]»hantlius had the happiest eftect upon the general condition of the patient, and it is doubtful if without these it would have been possible to Jiave pushed the iodide to the extreme dose given, or to have continued it for t he- requisite period. Another lesson to be learned from this case is, that the supervention of iodism seems to belong to small doses or to an early stage only of tlie administration of iodide of potassium. For a few days my patient complained of slight headache — frontal i)ain — and also of some coryza, but these symptoms quickly passed of}', and never troubled her again. There was on the other hand no gastric irritation produced, which has been set down by some observers as one of the first symptoms of iodic intoxication ; on the contrary, as we have seen, there was marked, relief, nay, up to the present, complete cure of chronic dyspej>tic troubles. A second train of symptoms belonging to the nervous system, and which have been described as a form of iodism, as neuralgia, ringing in the ears, convulsive movements, disturbed intelligence, ophthalmia, salivation, vomiting, polyuria, and cutaneous eruptions, was conspicuously absent. Neither was there anything like atrophy of the mamma or of the ovaries, if we are to judge of the latter by the free continuance of the catamenia. Two further questions of an important and practical nature would seem to arise out of this case. If it is necessary in a case of psoriasis to give doses of from 300 to 600 grains daily of iodide of potassium before the disease is reached, is it not likely that in many other diseases the- profession has failed to procure the benefits of this drug, owing to the- smallness of the doses administered ? In such an intractable disease as chronic interstitial pneumonia, I have lately seen marked benefit from large aration containing an alkaloid called atishie, which, though bitter, is only a harmless tonic. Aconitine is entirely absent from this powder, although tlie analysis of Wassowicz shews that there is aconitic acid in the root, along with a mixture of oleic, palmitic, and .stearic glycerides, cane sugar, vegetable mucilage, &c. (Dymock). As an anti-periodic, even when the fever is on, it is given in doses of from twenty to thirty grains of the powdered root thrice daily. It is given as a tonic in doses of five to ten grains, thrice daily. (2) Coptis teeta (Mamird). — The preparation exhibited is a powder of the dried rhizome. It owes its value to the presence of berberine in a soluble condition, and has been used as an intestinal tonic, especially where there is a tendency to a chronic catarrh of the bowels. The dose of the powdered rhizome is from five to ten grains thrice daily. (3) Thalicratura foliolosmti {PlUjarl). — The preparation exhibited is the powdered root. Dr. Dymock, of Bombay, has administered it in the for:n of a tincture ; and he finds, from his experience in the European General Hospital, that it is "a good bitter tonic, comparable with gentian." It is known to the native druggists of Bombay under the name of Plaranga, and owes its therapeutic property to berberine, which is found in large quantity in the roots, and is readily soluble therefrom in water. It gives a tone to the bowels, and improves the appetite during convalescence from malarial fever. Dose — Five grains of the powder thrice daily. There is also a watery extract made of the root, which may be given in do.ses of two grains thrice daily. N.O. MENISPERMACEiE. (4) Tlnospora cordifolia {Gulwel or Garola). — Tlie preparation exhibited is a powder of the stem which may be used in making NOTES 0\ SOME INDIAN DRUGS, WITH KXIIIUITS. OJ-J an infusion in tlie i)ro[)ortion of one ounce of the powdei' to ten Huiil ounces of cold water. The medicinal value of the jilant is due to a small quantity of berlierine. It is used as an alterative and tonic, and has enjoyed the rej)Utation amonj^ the ancient Hindoo writers of being an apla-odisiac, but as the drug is never prescribed alone as an aphrodisiac, its reputation is of a doubtful nature. Dose — -One to three ounces of the infusion. There is a starch obtained from tlie roots and stems of this plant which goes under the name of GulAceliclie Salica (the starch of Gnlirel), whicli is very similar to arrowroot in appearance and effect. It answers not only as a remedial medicinal agent in chronic diarrhoea and some forms of obstinate chronic dysentery, but is also a valuable nutrient when there is intestinal irritability and inability to digest any kind of food. I have myself had (ixperienco of the usefulness of this starch. Dr. Dymock says, through not having been washe'd, the starch has been found to retain some of the bitterness of the plant. I have tasted the starch myself and have not found it bitter to any appreciable degree, probably from the fact that ni}-- specimen was difierent, but I have no doubt that the starch has- some medicinal property in it from the minute traces of berl)erine which the plant contains. I think also that this dnig is useful whei'e there is an acid diarrhoea, due to acidity of the intestinal canal or acid dyspepsia. It is useful in relieving the symptoms of rheumatism. There is another l)reparation of this plant — the succus prepared from the fresh plant. It acts as a powerful diuretic. It is prescribed by the ancient Hindoos in gonorrhoea, with advantage. Considering that in the earlier stages of gonorrhoea we now try to reduce the acidit}' of the ui-ine by alkaline mixtures, it is probable that this drug acts by reducing the acidity of the urine in gonorrhoea. The do.se of the succus is from one to two drachms in water, milk, or honey, thrice daily. (5) Cocculus villosus (variously named Vasaiwel, Tduvel, I'diii, or Pdrvel). — There are two preparations of this plant : — (a) A liquid extract obtained from the root, and [h) A syrup prejiared from the leaves. It is a common hedge plant in Western India, especially in the Koukan, where it is generally used as a refrigerant in febrile disea.ses, and also as a gentle laxative. It has also been extensively used as an alterative in chronic rheumatic, and venereal diseases. Dose of the syrup — One to two drachms in water or goat's milk. Dose of the liquid extract — A drachm in water or goat's milk, thrice daily. N.O. Capparide.k (6) Cleome viscosa {Kd)i/>huti). — The px'eparation exhibited is an oil obtained from the seeds. The plant has a great reputation as a remedy for chronic otorrhea. Its action is chiefly anti.septic, as it contains a powerful volatile principle not unlike in smell to that of the mustard. This active ijrinciple has besides stimulating properties. The plant is highly viscous in every part, and is covered over with hairs, which are capped with sticky glands, and smell powei-fully. The i)lant was known to the ancient Hindus as " Adityaljhakta," as its delicate flowers of ricli golden hue are seen at tlieir best at sunrise, and hence called " Devoted to the Sun." 2p 2 948 INTEKCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. N.O. PlTTOSPORE^. (7) Pittosporimiflorihundmn (Yekadi). — The preparation exliibited is- a tincture. It contains a volatile oil, which is said to act as an anti- septic and stumulant to the mucous membrane of tlie bronchi. The dose of the preparation is a drachm and a half, thrice daily, in water or honey. N.O. GlTTIFER.15. (8) Garcinia mangostan (Jlaiu/i'stihi). — There are two preparations — a }towder and an extract (liquid), usefid in chronic diarrhcea and chronic dysentery. The value of these pre[)aiations lies in the yellow resin which the rind of the fruit contains — a characteristic of the fruits of the Guttifers. The resin acts like all other resins, as a stimulant to the mucous membrane of the intestinal canal. I am not sure whether the crystallisable substance, vianr/ostine, which Schmidt has obtained from the rind, has any particular therapeutic property. It is worthy of a trial, as the preparations are largely used l»y the Natives of Western India in chronic cases of intestinal catarrh. Waitz recommends a decoction of the powdered rind as an external astringent application. I liave no doubt that the resin adds to the value of this local remedy, by mechanically constricting the parts gently — an effect very often produced by uniform light bandaging. (9) Ccdophyllum inophyUum {Undi). — The pi'eparation exhibited is an oil from the seeds. It is known in Ceylon as Domha, and used for burning. It make a good embrocation in chronic rheumatic arthritis. It has a slightly stimulant action on the skin. N.O. Malvace/E. (10) Ada7isonia digitata {GoraJcli-chinch). — The jjreparation exhibited is an extract prepared from the bark. Dose — About thirty to forty grains a day, in small doses, every third or fourth hour, in intermittent fevers. The fruit pulp is acid, and makes a verj- pleasant refrigerating drink. When unripe, the fruit }>ulp is mucilaginous, but as it gets ripe, it assumes the appearance of dry pith, containing dry powdery acid starch-like stuff, enclosed in bundles of fiVtre, and surrounding the seeds. Walz has extracted an active principle from the bark, called Adansonin. The pulp is an astringent in diarrhrea, like gallic acid. N.O. RUTACE.!-:. (11) Toddidea acideafa (Jangll Kdli viirchi). — The powder is obtained from the root. It has been recommended by Dr. Bidie, of Madras, as a bitter tonic in debilit}', after malarial fevers, and in convalescence from exhausting diseases. I have tried it in the malarial cachexia of fevers, and find that it acts as a good stomachic tonic, improving the appetite, and aiding digestion. An infusion of the root powder, in the proportion of an ounce to ten fluid ounces of boiling water, makes a capital pre- jtaration. Dose — One to two ounces twice or thrice daily. Four years ago, I obtained a few pounds of the root from Di-. Dymock, and tried them with great advantage. The root contains a bitter principle, the exact nature of which is yet unknown. It was once known in Europe XOTKS ON 80ME INDIAN DKUGS, WITH K.XHimTS. OiO nnder the nauie of Lopez-root, as a remedy for diarrhcea, probably from the large quantities of yellow resin which its vascular and cortical systems contain. " The bark," says Dr. Dymock, "is remarkable for its large cells, tilled with resin and essential oil. (12) ^Ef/le marmelos {£<.el/>hal). — The preparation exhibited is a preserve of the fruits in sugar. It will be observed that the specimen is clear ; there is no trace of muddiness, indicating fermentation. The slices of fruit are solid, succulent, and not jagged. The latter condition occurs in fruit that is preser\-ed when it is ripe. It is worth}' of remark, that nearly all the English and even Indian ]n-eparations of bael are made when the fruit is ripe. This is a mistake. When the fruit begins to get ripe, and sugar appears in the pulp, the medicinal value of the fruit is reduced, if not lost altogether. The fruit should be unripe for preserve. In this state, there is round the small seed a mass of mucilage, which is a great agent in allaying irritation in the catarrhal inflammations of the intestines. The native physicians, especially the celebrated Vaidya Prabhuram Jivauram of Bombay, a venerable man learned in ancient Hindu medicine, and not unwilling to profit himself by the advanced researches of European therai)eutics, insist, in their preparation of the preserve, on using the fruit quite unripe, when the rind is green. The unripe fruit alone is highly astringent. The ripe fruit, on the other hand, is a mild laxative. This must be remembered if the preserve is to be used for the one or the other purpose. It is a common household remedy in Western India, as effective as it is handy, especially Avhere there is a tinge of scurvy in the patient. N.O. Leguminos.e, (13) Poti'/'tinia glabra [Kwanjd). — The oil exhiljited is pressed out of seeds. It is an exceedingly useful oil in cutaneous eruptions of the inflammatory tyjje — as, for instance, in chronic eczema after the " weep- ing " stage. It is an emollient of the best kind, and I have used it with or without oxide of zinc with great benefit. It is used in pityriasis and scabies, but I am not sure of its properties as a parasiticide. (14) Bauhinia parvifiorn (a variety of lulncJian). — The preparation is a kino, or dried extract obtained from the bark. Dose — 5 to 10 grains in dysentery and diarrhcea of a chronic nature. I have never used it myself. N.O. Lytiirack.e. (lo) Amiiianla hacci/era or A. vesicatoria {Aaya). — There is a liquor from the leaves of this strange ))lant which, as its name indicates, is " fiery " — quite a substitute for the Spanish blistering fly. Koxburgh first introduced it into the Eui'opean world. It blisters the skin, if the ethereal tincture is used as recommended by Dr., Dymock, " rai)idly, ■eflectually, and without causing more pain than the liquor ei)is])asticus of the British Pharmaco))aMa." Dr. Bliolanath Bose gives it internally in chronic enlargement of spleen in the shai)e of juice of leaves ; but as may be supposed from its vesicating eflect on the skin, the leaves are extremely acrid, and as a consequence must, and do, produce gastric irritation and positive pain. J 950 IXTERCOLONIAL MEDICAL COXORESS OF AUSTRALASIA. (16) Lawsonia olha (Mencfi or Ile/iud). — The preparation exhibited is an ointment made from the leaves. I do not know if this drug lias any therapeutic value. The natives of India, especially the Mahoniedan. males and females, use the leaves to dye tlieir hair, hands, feet, and nails. The leaves are bruised with lemon juice, and put on the parts to be dyed overnight, and sometimes for forty-eight hours. A rich scarlet staining of the parts is ol^tained. The dye is produced by the action of the acid of the lemon on a particular kind of tannin which the leaves contain. N.O. Myrtace.i^. (17) Eiifjenia jamhulana (JAmlml). — The following preparations ai-e exhibited : — (rt) Powder obtained from the seed. Dose — .") grains thrice daily. {h) Syrup obtained from the jiulp of the fruit. Dose — -A dessei't- sfioonful to a tablcspoonful thrice daily, in water. (r) Wine obtained from the pulp of the fruit. Dose — An ounce thrice daily. {(I) Acetum obtained from the i)ulp of the fruit. Dose — One to two teaspoonfuls thrice daily. The powder has been used by Deputy Surgeon-General Henry Blanc,, of Bombay, with remarkable success in the treatment of diabetes. In my hands, it has not fared so well, though I have given 30-grain doses, thrice daily. In many other hands, it has failed equally. The seed should be fresh, as it is liable to be destroyed by a kind of weevil which attacks it soon after, and sometimes even before, the fruit is ripe. The fruit is notably astringent to taste, though, when perfectly ripe and fresh, it is refrigerant. The preparations of the fruit ai'e used in bilious diarrhoea, and are highly astringent. N.O. Umbellifek.e. (IS) Il>/drocoti/le Asiafica (JJntmhi). — The preparation exhibited is a succus obtained from the leaves. The dose for children is from ten to twenty drops in honey, thrice or four times daily. It is good as an intestinal tonic where there is catarrh of the mucous membrane, follow- ing habitual constipation. It is mentioned in the old Sanskrit work of (Jhakradalla. On the Malabar coast it is used in leprosy, but Dr. Hunter who tried it in the Leper Hospital of Madras so far back as 18.55, says that the drug is not a specific. When I was surgeon in charge of the out-patients' department in the Jamsetyi Jijibhoy Hospital in 1886-87, I tried this drug in the anpesthetic variety of leprosy. At the instance of my friend Dr. Anno Moreshwan Kunte, B.A., M.D., who has charge of the Incurable (Leprosy) Asylum, attached to the Jamsetyi Jijibhoy Hos[)ital, and has recently had great experience in the treatment of leprosy, T tried ten grains of the powdered leaves of this plant in about fifteen cases. It had a distinct effect on tlie sensory nerves. There were no doubt an improvement in the cases. The anpesthesia disapi)eared. I think that the cutaneous peripheral branches of the troiihic nerves were stimulated, and the development of the tubercles- I NOTES OX SOMK INDIAN DRUG'S, WITH EXHIBITS. 951 stopped. In the mixed form of lein-osy wliere there are both tul>ei-cles and anaesthesia, if the latter can \>e stoi)ped the tubercles will not form, as the further degeneration of the parts supplied by the nerve.s is etlectually stojjped. Here is a good Held for further research. I must state howevei-, that I never used the powder in advanced cases of leprosy, and used it only in the anaesthetic form. Dr. Knnte bears me out in my experience. It is recognised by the " British Indian PharmacoiKeia." N.O. Co.Ml'OSIT.E. (19) SphercnitJiKS Indices {Gurak/i-miindi). — The prepai'ation exhibited is a water, containing in solution a very small quantity of the viscid oil, obtained from the i)lant. It was known to the ancient Hindus as au intestinal parasiticide, and is mentioned in Sanski'it works as muuditihd. It is used as a diuretic in Java, and is excreted by the kidney and skin ; both the urine and persjdration of {)ei'sons using it smell of the volatile oil. It is a powerful altei-ative and tonic. (l2f>) Blumea (several sj)ecies), commonly known in Boudjay as Ji/idi/ibnrdd.— The preparation exhibited is an insect powder made from the leaves of tlie various wild species of Blumea and Anona squamosa. The Blumeas have a rei)Utation of destroying tieas. The powtler of the Anona appears to be added to heighten the action of the Blumea leaves. They are both possessed of powerful smell, and contain large quantities of volatile oils in every part of the [)lant. In Bombay, floors attacked l)y fleas are brushed or swept with bundles of the blumea plant, dried or fresh. (21) Edipta alba vd prodrata {Mdkd or Blhrungi Rdj). — The prepara- tion exhibited is a succus oV)tained from the leaves of the plant, which grows very commonly by the way side and green alleys in Bombay. It was vised by ancient Hindus as a remedy against hepatic and splenic eidargements. Mr. Wood considers that the plant may some day supersede taraxacum. Dose — One or two drachms thrice daily. N.O. Apocynace^. {'I'l) Alstonia .sdtolaris (Sdi/'H/i). — There are three preparations exhibited — there is an extract, a liquid extract, and a powder of the l)ark. From the powder of the bark an infusion is prepared (half an ounce to ten ounces of boiling watei- infused for an hour and strained). Tills plant has a parallel in the dry inland warm parts of Kast Australia, in the alstonia constrida. which Bai-on .Sir Ferd. von Mueller says {I'kh " Select Extra Tropical Plants " p. 30), is " aromatic-bitter, and regarded as valuable in ague, also as a general tonic." The learned Baron recommends that the sap of all alstonias should be tried for caoutchouc. The tree was known to the ancient Hindus as saptaparna, i.e., having seven leaves in a whorl, wherever they rise, unless abortive. It is still used by the natives of India as a powerful tonic and anti-periodic. It is known to the natives of ^lanilla as osition of this plant given in the "Year Book of Pharmacy" for 1881, and the jilant has a recognised place in the " British Indian Pharmacopeia." (23) Holorrhena anti-dysenterica {PCiudhrd, i.e., white Kudd). — The exhibit is the powdered bark. This plant is entirely distinct from the Kdid or black Kudd, known as Wrightia tinctoria, the bark of wliicli has often been substituted for the Holorrhena, and found inert. In selecting samples therefore of PdiuUint Kudd, this fact must Vie remembered, as the Wrightia bark has not got the anti-periodic, tonic and anti-dysenteric properties of Holorrhena. The root bark of Holorrhena is bitter, that of Wrightia is only moderately so, if at all bitter. The bark of Wrightia tinctoria, besides, colours the saliva reil. Holorrhena bark has none of this property. It is essential to know this diagnostic difference. In India, Holorrhena is largely used as a remedy in dysentery and diarrhoea. The dose of the powder is ten to twenty grains with opium. A decoction of the bark may be made l)y taking two ounces of the bark, adding it to two pints of water, and boiling it down to a pint. Dose — Half an ounce to two ounces, with a suitable quantity of tincture of opium, four times a day. (24) Flunieria acutifolla {Kliairchaynpd). — The preparation is an extract from the bark of the tree, given in doses of from five grains to iiiore. Extreme care should l>e taken in using this drusr. It is found useful in intermittent fevers and gonorrhoea. I have i-eported a case * which occurred in my practice in the ^Military Detachment Hospital at Thana, where a jH'ivate swallowed about two inches square of the thick bark to relieve constipation. He suffered violently from vomiting, giddiness, and dilated pupils ; clammy sweats on the face ; cold extremi- ties ; intellect clear. He recovered. Eight days subsequently, he had exfoliation of the epidermal tissue of the whole body. The poisonous ]:)roperties are in my opinion due to a glucoside having a purgative action. It must be remembered that the plant is leafless for nearly six months in the year; its glucosides, therefore, are abundant in the quiescent state, tlie sap undergoing concentration, and rendering the active principle obtainable in larger quantities from a given square inch of the Ijark, as compared with what may be obtained when the leaves are out. N.O. ASCLEPIADACE^. (2.'5) Hemldesinus Indicus (Atia/d Mul ov Upalsar). — The preparation exhibited is a liquid extract obtained from the fresh root. A drachm or two thrice daily, in two or four ounces of fresh milk and sugar or warm water, act as an excellent alterative, tonic, diuretic and diaphoretic. Tlie plant is a well-known j)opidar remedy in India in all kinds of constitutional debility, especially among children, who take it readily. On account of its diui'etic proj)erties, it is of especial use in rheumatic * Vide Brigade-Surgeon Lyons' " Medical Jurisprudence," Bombay, 1888, p. 200 ; and vide " Bombay Medical and Physical Society's Transactions,'' vol. ix., nr\v series, 1887, p. xiv. NOTES ON SOMK INDIAN DKUGS, WITH EXHIBITS. ^')'3 '.iffections, and in skin diseases arising from nial-nutrition and deficient action of the excretory organs. 3Iy friend, Dr. Guerson da Cunha, of Bombay, uses it largely, in a successful manner, as an alterative. N.O. BlGXONIACE-E. (26) Oro.ci/lum IiuUcnm, Syn. Calosaiifhus Iiidica [T'-tu). — The pre|,)arations exhiljited are {a) powder of the bai*k ; (6) an oil obtaint'ri(//ti(l (seeds of plantago ispaghvda), natural oi-der Plantagineje. When moistened, these seeds, whole or powdered, swell up, and are very demulcent, often sto])])iiig diarrluea, wliich has resisted all other treatment. i'lacJioyia Fehvifuye.— \\\\v\i i|uinine could be ol)tained only from Peru, the price was so high as to be prohibitory, so the (Government of India obtained seeds and cuttings of various species of cinchona, and planted them in India, on the Himalaya mountains in the north, and the Neilgheri-ies in the south, where they have been acclimatised so successfully that, after supplying its own State hospitals, Government sells to the public cinchona febrifuge at twenty rupees per pound. On its tins the following label is pasted, giving an analysis of the mixed alkaloids in it : — Analysis. Quinine . lL'-l(i ter cent. Quinidine . . . . 00---)G Cinchonine . 2.5-00 Cinchonidine . 34-98 Amorphous alk iloid .. 8-20 Ash . 6-62 Water and colouring matter . 12-48 Total 100-00 „ It forms a brownish-yellow powder, having a disagreeal)le odour, and such a nauseating taste, that it cannot be given in large doses, like cjuinine, without causing vomiting. To prevent this, it is made into pills of two giains each with gum water, two of which are gi\en every three houi's, while fexer is absent. Its effect as an antiperiodic is thus secured without Ijad i-esult, and the drug is distributed to the million by native doctors, vaccinators, and policemen. The importance of it may be judged from the fact that fever causes about three-fourths of all the deaths among the natives of India — all other causes being insignificant, even including epidemics of small-pox and cholera. The death-rate from cholera is only 1-8 per 1000 in tlie very worst parts of lower Bengal — a damp climate — while it is only 0-2 per 1000 in Sindh — a dry climate. Erf. Jamholmui', Liquidtim (Kemp). — Fluid exti-act of the seeds of JfimhvJ, natural order Myrtacete, Eugenia Jamljolana (Blanc), or Syzigium Jambolanum (Waring). It was first introduced into general use by Dr. J. H. Blanc, Bombay Army, in 1844, as a most useful drug for diabetes. Dose — One or two fluid drachms in watei- three times a day. ■958 IXTEHCOLOXIAL MEDICAL CONfiKESK OF AIJSTKALASIA. While taking j.-uiibul the diet is not restrieted in any way, as jambul has a remarkable power of preventing starch from being converted into sugar, the urine in two or three weeks liaving its specitic gravity reduced from 1042 to 1020. It is carefully prepared from tlie fresh fruit every year, in Bombay, by Messrs. Kemp and Co., who doubtless could also supply the other things mentioned in this paper. Joara IIkvI, or Fever Killer, a patent preparation of Mi'. Bowden, Madras. It is like Warburg's Tincture, a combination of quinine witli certain aromatic substances, which are poweiful diaphoretics; but it has a fai' nicer taste than Warburg's Drops. It often cliecks inter- mittent fever, when all other things have failed. Like all othei' febrifuges in India, it sliould be pi'eceded l)y .i purgative — pil. podophyl. being generally preferred. OX A NEW :\IODE OF ADMINISTERING THE PROTOXIDE OF IRON. By Thomas Sheakman Ralph, M.R.C.8. Eng. Associate of the Liinieau Society, Loiuloii. It is both interesting and instructive to look back on the various ferruginous prejjarations wliich from time to time have been placed :it the disposal of the medical practitioner, to aid him in what no doubt was the thing needed, viz., a further accession of iron in the circulatory system, and when this effort proved successful, most probably the result was favourable both to the patient and to the administrator. One of my oldest Ferric acciuaintances was the " Ferrum tartarisatum," and with this there was an ancient form — and a good one — -but which has well nigh been cast into oblivion, with much likelihood of becoming a rusty compound. For, as most of us know, or are likely to know, tli«? old Oriffith's mi.xture. which has for its base a subcarVjonate of iron (or rather a carbonate of the protoxide), while it was good and active during its green coloured state, soon :issunied a rusty brown, and becaiue inert. And the mixture also was not agreeable to tlie taste, owing to the companionship of pulv. myrrha?. These forms, with the old rust coloured oxide of iron, which yeaj's ago was administered in very bulky doses, and seemed to l)e serviceable in its emi)loyment, have all waned before fresh combinations of the base, i.e., ferrum \uiited with some acid or saline. And each has had its day, and number of patients, fair tibial, and share of approval, and have bestowed, no doubt, a modicum of benefit. Our lists of comliinations of ferrum may l)e classed roughly under three groups : — The metallic forms and the oxides, including the carbonated oxides ; the saline forms, or those combined with mineral acids; and those compounded with vegetalde acids. NEW MODE OF ADMIMSTElUXfi THE PROTOXIDE OF IKO\. 950 Tlie first group appears to me to he an unsatisfactory form, the mtitallic base requiring some internal menstruum to introduce the iron gratefully into the system, and the oxides ready at any time to become iiiert by the absorption of oxygen in transitu. Tl)e saline form tending to a styptic or astringent action, and as such, perhaps, passing slowly and uncertainly into the blood system; or, l)ossibly, the iron becomes engaged with decomposed ])roducts in tht? stomach, and passes into the form of carbonate or peroxide. The third grouji of vegetable acids and iron aj)pears to me to approacli that condition of iron which closely resembles tlie above changed or •decomposed form, the result of change in tlie stomach. In none of these forms is the iron in a state of true jirotoxide, and if this condition is the necessary one, and the best for absorption, then all iron, which is not in proto-form, is likely to be so much waste; hence, ])erhaps, came the necessity for the exhibition of large doses, as was especialh'' the case in the use of the peroxide of iron, of which half ounces were formerly given, and out of which the absorbents drew, or obtained, a modicum of protoxide, or a form of iron readily absorbed, the rest being useless lumber. Phosphate of iron seems to suggest a means of sujiplying two important elements for the blood and hard tissues, hence ])hosphorus has appeared combined not only with iron, but also with lime — another much wanted ingredient; as if in j)reseuting these two combined, iron and phosphorus, we said to the system of our ))atient — Utrum liormii laavi.H (i.ccipe. Years ago tiiis consideration occurred to me, that if we could increase the amount of iron and phosphorus in our cereal food, we should perhaps be more successful in stealing our way into the systems of our patients; but all this is speculation, perhaps a necessary one for the next and rising generation to brood over, and supply a new formula, and boast itself of the pharmaceutical and therajjeutic wisdom thereof. The formula which I bring before your notice, I think, is likely to supply to a great extent a needful active form of iron, and will prove a pleasant, or at any rate, a non-disagreeable administration of an im]iortant element to the animal economy. I wish briefly to inform you that the formula which I advocate is one in which the pi'otoxide of iron (the essentially active and advantageous form in which iron can 1>e ])resented to the system), is in chemical combination with albumin, and that under this condition the stomach does not appear to be offended at its introduction ; and that it does not act as a styptic, seldom causes constipation, and moreover is not in a hurry to assume that peculiar complexion wliicli indicates a change of value in its usefulness, i.f.., rustiness or ]>eroxidation. The method of preparation requires to be strictly carried out, and when it shall fall into the hands of a modern ])harmacist, I have little doubt it will be more suitably prepared than 1 have been able to effect; but the basis — the protoxide state — nuist be maintained. T have made trial of it in children; also in those adults who have seemed to require the administration of iron, and have found marked and rapid beneficial results. I should like it to be tried in some cases of pertussis, but more especially in tyi)hoid fever, when exhaustion •comes on, from what to me seems little recognised in the progress of 960 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA, this fever, i.e., the loss of a large amount of iron in the foiia of lisemoglobin, as well as in the direct loss of blood from the idceration of the bowel structure. An effort in the direction of supplying this serious loss is made by the employment of liq. carnis, which to my mind is by no means a pleasant remedy, nor one which I feel inclined to recommend, as I look upon it as stale food when compared with freshly prepared meat broth. Albuminate of the Protoxide op Iron. Take thirty grains of protosulphate of iron, and dissolve it in about six ounces of boiled water, and tilter. To this add liq. ammonite in excess; gently stir, and allow the precipitate to settle; then syphon otf the supernatant fluid, and add more water ; allow to settle again, and when the precipitate has fallen as densely as possible, syphon oft" again, and add about a teaspoonful of fresh white of egg; add more water, and allow to settle thoroughly; syi)hon off carefully, and place the precipitate in a shallow vessel and allow the excess of water to evaporate in a water bath, at a temperature below the coagulating heat of alljumen; when the precipitate has become well thickened, add confectioners' sugar to thicken it still further, so that it can be made into tablets. ►Sixty from the above mass will make a convenient size, and each will represent half a gi'ain of the sulphate, and constitute an ordinaiy dose for a child. SECTION FOE DISEASES OF THE SKIN. PRESIDENT'S ADDRESS. By James P. Ryan. Chevalier of the Tjegion of Honour, Sec. Gentlemen, — When thinking of a subject for the short address which it is my pleasui'e as well as niy duty to deliver before you this afternoon, it struck nie that a brief enumeration of the various kinds of skin affections which have come under my observation, and a short account of some of them, might not be without interest. The experience to which I shall appeal has been gained during a period of fourteen years at the Melbourne Hospital, the last year and a half of which has been at the skin department, some fifteen years' attendance on the Abbotsford reformatory schools, and from private j>ractice. Unfortunately no statistics are available, so that when speaking of numbeis in relation to cases, I am but expressing an opinion. For this reason, I am unable to say if diseases of the skin are more prevalent here than in (Ireat Britain. But the varieties which come under one's notice are much the same in Mell>ourne, Paris, New York, or London, though the relative proportions in which they occur are probably different in each place. For instance, scabies, which is common enough in London or Glasgow, is less frequently encountered in New York and Melbourne. Indeed, in Melbourne it is an uncommon disease. Nor is the reason far to seek. It is for the most part found associated with jwverty, dirt, and over-crowding — conditions which as yet are rare in Australian towns. Then on account of our warmer climate, and the plentiful supply of water which even the poorest in Melbourne have at hand, general washing and bathing is more a custom amongst the humbler classes here, than it is amongst the same classes in England. The appearances classed as scrofuloderma — including lupus iu all its forms — is certainly less frequently met with here than in the older countries, very largely through the better feeding of our population. Dr. Bulkley, in his manual of "Diseases of the Skin," gives an analysis of 8000 ca.ses collected from private and hospital practice in New York, showing the relative frequency of these diseases in that city; and his tables, I think, express pretty accurately the relative 2q 962 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. frequency of such diseases in Melbourne. Eczema there, as here, is the commonest of all, and accounts for one-third of the SOOO cases. Then come — Acne in the Proportion of 12 per cent. Syphilis „ „ 10 „ Phthiriasis „ 5 „ Piingworm „ 4^ „ Psoriasis „ 4 „ Urticaria „ 2| „ Lichen „ 1^- „ Zoster ,, 1 „ And the others in varying proportions under 1 per cent. At the Melbourne Hospital, the syphiloids occupy the pride of place, no doubt through the fact that the great majority of patients suffering from sy]>hilis are drafted into the skin department. Sycosis (which only occurs twenty-seven times in Bulkley's 8000 cases) is common enough here, the non-parasitic form being the one usually met with. The tinea tricophytina barbje is, I think, a rare disease with us. Thei'e is a milder form of inflammation, eczematous in character, which attacks the region of the beard and whiskers. Its more superficial character, the fact of its often extending to non-hairy parts, or its appearing simultaneously upon them, and its being easily amenable to treatment, distinguish it from true sycosis. I liave met with two cases of chloasma uterinum, and the occurrence of the disease in lioth was coincident with i)regnancy. In one it was pi-esent for the first time, in the other it had i*ecurred during four pregnancies, disappearing after child-birtli, to make its reappearance in the second or third month of carrying. In this connection, I may mention a pigmentaiy syphiloderm in a young man who had had a chancre five months previously, followed by other evidences of secondarj" syphilis. The pigmentation was deeply marked, and spread out in maj) form on the back of his neck, between and on the shoulders, and down the arms to near the elbows. It bore a strong resemblance to tinea versicoloi". To clear up the diagnosis, no local application was used, and it disappeared under internal treatment by mercury. Prurigo occurs only once in Bulkley's tables. I am aware that other affections, such as phthiriasis, papular eczema, lichen urticatus, pruritus, &c., are often classed as prurigo ; but I am convinced that it exists in a form sufficiently characteristic to entitle it to a separate and distinct name. Take the following case as an exam{)le, and I have come across many others of a similar kind : — A middle aged man, not over robust and of sedentary habits, is suddenly attacked, most frequently during the night, by intense itching prksidkxt's Ai)nHi;8.s— section for diskasks of thk skix. 963 of the inside of one or botli knees, the affected area sometimes extending half way u]) the thitrh. At tlje commencement, a number of small pale-coloured papules may be seen, as well as felt, which are evidently slightly enlarged papill.'e. The skin soon becomes infilti-ated from the irritation produced by scratching, the papules are torn, blood is efl'used, and in a few days the affected ])art shows the type of ordinary senile jii'urigo. There is then thickening, increased pigmentation, a slight fui'furaceous scaling, and, at tlie end of a week or ten days, the skin has usually returned to its ordinary healthy condition. Many such attacks may occur during the year, and the patient is convinced they are most frequently brought on by indiscretions in eating and drinking A disease which prevails hei'e amongst children more frequently than is suspected, and which on account of its contagious properties should be recognised and treated as early as jiossiple, is impetigo contagiosa. The lesions begin as small separate red itapules, which vapidly develop into vesico-i)Ustu]es, and dr}- into yellow or brownish crusts, and in some cases of unhealthy sul»jects, they become ecthyniatous in character. The disease affects by preference the hands and arms, the feet and legs, the back and neck, ami it often extends to the face and trunk. Here is the history of an out-break in a family, in which the father, mother, and six children were attacked : — One of the boys, aged 12, was away from home for some time, and came back with an eruption. He usually slept in the same bed with -a younger brother, who soon took it. Then an elder sister was attacked, who probably gave it to a baby in arms, and it spread to the mother, father, and the other children. The only member of the household who escaped, was a girl of 16, who acted as maid of all work. Here the extremities were affected in every case, the face in two, and in one a few spots were found on the trunk. The question arises, might it have beeit scabies % T think not. The eru])tion was more frequently found on the extensor aspects of the limbs, it attacked the face, it showed no special j>redilection for the wiists and interdigital spaces ; itching, though sometimes present, was not a marked symptom, and though I made frequent searches, I failed to find any trace of the cuniculus, or of the acarus itself. Then in every case there was some febrile disturbance. The diseases with which it is most likely to be confounded, are varicella, })ustular eczema, and scabies, but I do not think there should be much difficulty about the diagncsis. Amongst the rarer forms of skin diseases which have come under my notice, I may mention dysidrosis, pemphigus solitarius, pityriasis rubra, ichthyosis, and leprosy. The case of pityriasis rubra was a typical example of the disease. The patient, a German about 30 years of age, Lad had it for three years when I first saw him. He informed me it began as a red, somewhat itchy patch on the chest and abdomen, and 964 IXTEKCOLONIAL MEDICAL COXt;RESS OF AUSTRALASIA, quickly, that is within a few weeks, extended over the whole body, and tho.t it has remained about the same ever since. There was reddening, but without any thickening of the entire skin, with the almost constant formation and shedding of fine branny scales. Sometimes lai'ge portions of the skin were quite smooth and glossy, and then the redness was most intense. There was little or no itching, his urine was free from albumen, and his general health appeared to be fairly good. He often complained of feeling chilly, though he said he always felt better in the cold weather. Hot bran baths appeared to allay temporarily the irritability of the skin, l»ut although he had been under all sorts of treatment by different medical men, from none did he derive any permanent benefit. 1 have seen only one well-marked case of dy.sidrosis, the cheiro- poiupholix of Jonathan Hutchinson, for I believe the two are identical. It occurred in a young and rather delicate woman, a seamstress by occupation, and had existed for about two months when I first saw her. The sago-grain appearance of the deeit-seated vesicles was sometimes exceedingly well-marked. She got well in three or four weeks under mineral tonics and bitters internally, the local treatment consisting in keeping the hand constantly covered, and ai>i)lying lead and belladonna lotion. Zoster has come under my notice much more frequently in adults than in children. The two following cases are of some interest : — A man of 55 years had intercostal neuralgia for a week, when a crop of papules ajtpeared in the site of the pain. Tiiey were situated on an inflamed base, fresh ones appeared froni time to time, but at the end of a fortnight they had died out, leaving liehind some discoloration, and the neuralgia persisted for ten days longer. There was no vesiculation, for I saw him frequently, and watched him carefully during the course of the disease. In this case the skin lesion was very mild, or aborted as Hebra terms it ; but the neuralgia vpas exceedingly severe and persistent, and required for its amelioration the ahnost daily use of subcutaneous Injections of morphia. Tlie other case was that of a delicate girl of 11 years, who complained of pain in the right side of her head. In a couple of days a few vesicles appeared above the eyebrow and on the temple, and the pain ceased. No fresh ones were formed, and the disease rapidly died out, but she complained of something being wrong with her right eye, and on examination I discovered a central corneal ulcer evidently the i*esult of a broken down vesicle. The ulcer was tedious in its healing, and left a facet or flattened spot (not a nebula), which spoiled the curve of the cornea, and resulted in iiermanent astigmatism. I have seen here only one case each of ichthyosis and leprosy, both of which will by and by be more particularly brought under your notice. Malignant pustule nuist surely occur in up-country districts if not near TREATMENT OF THE MORE FREQUENTLY MET WITH SKIN DISEASES. 965 town, and yet I have not met with it here, though I have seen it in ether countries. So far then as my experience goes, the skin diseases Avhich come inider the notice of tlie physician in Melbourne are identical in character with those which i)resent themselves to the medical ma)i in Europe and America ; and as yet, neither climate nor surroundings here have developed any novel feature in the etiology and morphology of these affections. NOTES ON THE TREATMENT OF SOME OF THE MORE FREQUENTLY MET WITH SKIN DISEASES. By R. L. Faithfull, M.D. New York, L.R.C.P. et L.S.A. Lond. Eczema. This form of skin disease is probably brought under the notice of the physician or surgeon more frequently than any other, and not infre- quently gives him the greatest amount of difficulty to treat ; for although the prognosis is favourable generally as regards its curaljility, yet the length of time and patience to bring this about differs widely according to the form of eczema under treatment, as well as to the age, habits, and general condition of the patient. The treatment being local, or both local and internal, due attention should be paid to the pathological condition, as well as to any co-existing constitutional disorder or organic affection present. This being taken for granted, I take pleasure in bringing to the notice of my professional brethren some drugs and local applications with which good results have been brought about when other remedies appeared to have failed, and which now I am in the habit of prescribing, if not otherwise contra-indicated. In cases of eczema attended with acute violent inflammation, intense itching, swelling, and i)ain, I prescribe "jaboiandi" or " pilocarjnne," alone or in combination with acetate or citrate of ])otash, digitalis, aconite, veratrum viride, pulsatilla, or rhus toxicodendron ; and apply locally some soothing powder, such as starch or chalk, etc., which, if it is desirable, may be nnxlicated with any drug or fluid extract that is soluble in alcohol, ether, or chloroform, in the following way : — Dissolve the drug or fluid extract in any one of the above solvents, then carefully and thoroughly mix in a mortar with pestle a given quantity of tliis medicated solution, according to the requirements of the case, with a given quantity of the starch or chalk, or any. other insoluble powder. This being done, ]>]ace the medicated powder on a flat open dish to dry (heat, as a rule, should not be employed in the drying process): when thoroughly dry, it can easily be reduced to an impalpable powder, and is then tit for ap]»lication. The advantages of thus medicating powders for topical application Are — (1) A much wider range of drugs can be used, and the >juantity of 966 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. the medicament can be most accurately determined ; (2) tlie powder absorbs the moisture present, and brings the medicament in direct contact witli the diseased surface ; (3) it is generally well borne, can be easily applied, is cool, cleanly, and effective. The disadvantage is the cost "of preparing (propei-ly) small quantities of such powders, as it is always advisable to have them fresldy made. In some cases, oils or ointments are more grateful, and these can be medicated in various ways according to the indications present. When these are badly borne, soothing lotions of boracic acid, carbolic acid, or the fluid extracts of calendula, phytolacca, or grindelia robusta, diluted, may be advantageously used. In the more chronic cases, I combine the pilocarpine with some of the mineral acids or acid glycerine of pepsine, liq. pot. arseniatis, liq. sodae ar.seniatis, oxalate of cerium, or nux vomica. , Eczema of the scrotum and genital organs has yielded well under the internal use of tinct. hoang. nan. conctd. alone or combined with acetate or citrate of potash, together with one of the following local api)lications: — R Hydrargyri oxidi flavi grs. x- xx, hydrargyri ammoniati grs. x-xv, zinci oleatis 3j-3jss., vaseline ad. I}, mix with or Avithout the addition of camphor grs. x-xv ; or should the above prove too stimulating, apply the following : — R Bismuthi oleatis Sij-Siv, ungt. zinci oxidi ad. jj, mix. Eczema of the palms of the hands is one of the most obstinate forms of this disease. In chronic cases, the following has proved most satis- factory in removing the hard cuticle : — R Thymol, grs. x-xx, acidi salicylic 3j-5jss., saponis mollis ad. 3 ij, mix. Hub a little of this well in over the part once or twice a day, or every second or third day, accord- ing to the effect produced, let it remain on from half to one hour, then wash off with water as hot as can be borne, into which a teaspoonful of pulverised borax to the pint has been dissohed, and after di-ying rapidly by mopping with a soft towel, ap])ly one of the following ointments : — R Bismuthi oleatis Sij, chloral cum camphora 3 j, acidi salicylic grs. x, ungt. zinci oxidi ad. ^ j, mix. ; or, R Resorcin grs. xxx, glycerini 3j-3 ij, vaseline ad. J ij, mix ; or, R Hydrargyri ammoniati grs. xx, hydrargyri oxidi tiavi grs. xv, zinci oleatis 3j, vaseline ad. 3 j, mix. Tertiary Syphilitic Ulcers. The diagnosis of these is not at all times an easy matter, for obvious reasons, but a careful examination into the history of the patient, the situation of the ulcer or ulcer.s, and a thorough insi)ection of the rest of the body, will generally throw sufficient light ui^on the case. Still, in doubtful cases, which not unfrequently occur, specific treatment may be the only means of clearing up the case. These ulcers are prone to occur in subjects of oldstanding syphilitic taint, and are generally due to one of the late lesions of syphilis, viz., an ulcerating gummatous, tubercular or ecthymatous patch, but no matter what may l«e the starting point, an ulcer is produced with the following suggestive features : — The nlceis are circular, oval, or horse-shoe shaped, excavated, with edges more or less hardened, regular, sharply cut, j)erpendicular (sometimes slightly overhanging), and of a dull red or livid colour, with a pultaceous floor, and a tendency to scab over if exposed to the air. They are usually painless, unless through injury or NOTES ON A FATAL CASE OF PEMPHIGUS. 967 by their position they bccojue inflamed, or the periosteum becomes involved in the ulcerative process, and if not treated, tend to pursue a l)rotracted course. In the treatment of these ulcers, the following prescriptions have given me much satisfaction: — li. Potassii iodidi vel sodii iodidi 3j-3ii.j, liq. ferri iodidi conctd. 3 j-3 ijss, glycerini ' ij, aqu;e chloroformi ad. jviij, mix. One tablespoonful in water half an hour after meals. II. Ext. erythroxylon cocie ti. ^j-^ij, ext. stillingia? fl. 3 v-^ ij, Syr. menthai piperitte J ij, aquje ad. | viij, mix. Tablespoonful in water an hour after meals. It -was from Dr. Robert \V. Taylor, of New York, that I first learnt the value of ext. cocje fl. in syphilis, as an adjuvant to specific treatment. Lately, I have used the ext. kola nut. fl. (sterculia acuminata) in doses of m. x-xxx or more, with equally as good results as the ext. coca? fl. It is far pleasanter to take, and is not so apt to disagree. Many patients, after having taken the " coca " for a short space of time, complain bitterly of its nauseating and disagreeable taste, and beg to have the drug discontinued. I now prefer using the ext. coca3 in pills of grs. iij each. In some cases, I find the additional use of mercury of the utmost value, and my favourite ])rei»aration has been the tannate. Local treatment consists in bathing the ulcer or idcers tiight and niorning for ten to twenty minutes, with water as hot as can be borne, then applying one of the following powders : — 11. Hydrastin 3j> baptisin 3j, iodoformi ^ iij, mix, ft. pulv. Dust lightly all over the ulcers, after bathing and mo})ping dry. R. LTngt. zinci oxidi ; apply thickly upon a piece of lint large enough to cover the ulcerated surfaces, cover over with a piece of indiarubber tissue, and bandage snugly. li. Alnuin 3j, hydrastin 3j, baptisin 3j, zinci oxidi ^ '^j, mix, ft. ])ulv. Dust lightly over the ulcers after bathing, if the iodofoim is objectionable. For some time past I have used salol, alone or in combination with iodol, zinci oleas, bismuthi oleas or .subnitras, with results, if anything, better than those ])roduced by iodoform. The above applications are certainly far pleasanter in every respect for the patient. Note. — The fluid extracts used are those prei)aved by Dr. E. E. Squibb, of Brooklyn, New York ; and Parke, Davis and Co., Detroit. NOTES OF A FATAL CASE OF PEMPHIGUS. By Alfred Austin Lendox, M.D. Lond. Lecturer ou Forensic Medicine in the University of Adelaide ; Honorary Medical Officer, Adelaide Children's Hospital ; Honorary Assistant Physican, Adelaide Hospital. During the five years that I have piactised in Adelaide, with oppor- tunities for observation at both our hospitals, I have oidy met with this one case of pemphigus : — Edith B., ait. 5, living at Kingston on the south-east coast of this province, was admitted" under my care at the Adelaide Children's 968 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. Hospital on July 5, 1886; and, with the exception of a week in the ensuing November, remained there till September 23, 1887. Her history was as follows: — Family history good; no member of it had suffered from any special skin eruption. About Christmas 1885, an epidemic of so-called '* native pox " occurred amongst the children at Kingston ; all recovered except Edith B., who never got rid of it, and seven months later she was sent up to Adelaide for treatment. On admission, her general health seemed to be very good, and she Was not feverish. There was no evidence of a syphilitic or of a strumous taint, or of any lesion of the nervous system. She jn'esented, however, the chai'acteristic eruption of pemphigus vulgaris, distributed mainly into two great groups of blebs. The i^pper group occupied the face (including the eyebrows and ear), neck, chest, both front and back, and axillje, and comprised numerous tense bullae of the size of a pea, and equally numerous scabs and stains of former bulla;. The lower group occupied the front of the abdomen, the pudenda, and upper part of the thighs, and embraced every variety of size and stage of the lesion. Here were seen the early commencements of the disease as small reddish papules ; the reddish ])apule a little more advanced, with a bleb on its summit about the size of a pin'b head ; the fully developed blebs of different sizes (some half an inch in diameter), of ovoid shape, with smooth distended and translucent cuticle, and clear yellowish serous contents ; other blebs somewhat flaccid and pendulous, with perhaps some turbidity of the lower half of their fluid contents; blebs still more flaccid from escape of fluid, with the cuticle wrinkled and in some cases umbilicafced, or else no longer raised above the surface, and showing a ring of inflammatory redness at their margins ; excoriations of a quite superficial nature, and scabs from drying of the eff"used serum ; stains of a rosy red or a deep purple tint, but always darker at the circumference than towards the centre. There were single scattered blebs seen here and there over the back and on the extremities, as though the tendency were for the eruption to spread downwards, and later on this proved to be the case. None were noticed on admission on either the palms of the hands or soles of the feet. A very considei-able amount of iri-itation accompanied the eruption, causing the child to rub herself and aggravate her condition ; and at night-time the temperature was usually somewhat raised, occasionally reaching 102° or 103°. For a few days, tlie child was kept under observation without any drug being administered, but owing to the rapid spreading of the eruption, Fowler's solution was prescribed in ui. ij doses thrice daily, the dose being gradually increased to m. vijss. tlnice a day, without any toxic symptoms being produced. Under this treatment, altliough crops of fresh sj)ots appeared from time to time, many of which ran an abortivt; course, the disease gradually improved, the scabs cleared off', and only the pigmented stains were left, which were observed to be of a much deeper tint in cold weather. On the medicine being discontinued, a few more blebs ai»i)eared, showing that the disease was suppressed but not cured, but they all aborted when the arsenic was resumed. Dr. Vaughan (the house-surgeon) made many painstaking observations of individual bulhe, but no general conclusions could be drawn as to their natural course of develo[)ment and duration, because, for example, of two fresh papules noticed on the same day, one would speedily abort NOTES ON A FATAL CASH OF PKMPIIKiUS. 969 and the other perhaps run a protracted course until the scabs formed on the seventi), or even as late as the tenth day. Moreover, the observa- tions were vitiated by the fact of the child taking arsenic all the time ; but I am convinced that whilst under the influence of this drug, no fresh ci-ops had the same vigor or vitality as the original erui)tion. One striking feature was noticed, and that was this, that the fresh crops did not s])ring up in numbers like the vesicles of herpes" zoster, but when one s()ot has appeared and matured in a fresh situation, others aj)))eared in its neighbourhood as tiny satellites and subsequently coalesced with the original bleb, suggesting some local method of infection, and the stains left nfter the bullai liad disai)i)eared inteisected one another ; one or two attempts, however, at inoculation in distant situations, failed. On one occasion, hfematuria was noticed ; on another, an attack of bilious vomiting, attended with pyrexia, induced me to discontinue the medicine, but on the following day a bleb formed in the palm of the hand. Several times subse(juently, wlien all the bulhe had disap])eared and the medicine ])erlia})s had been discontinued, a pyrexial attack occurred, and in a few days a fresh e)'U])tion of bullai was noticed. Once the jiatient was sent out under the supposition that she was cured, only to leturn in a Aveek's time and to remain in again several months, during which time fresh blebs frequently appeared, but they were seldom numerous, and tliey readily yielded to treatment — the arsenical solution being ])ushed sometimes to the extent of ni. xvj thrice a day. Wlien after some weeks no more bulla? had appeared, although we were led to expect them on account of febrile attacks, she was finally discharged marked with innumerable .stains, and the skin tinted elsewhere with the peculiar brownish colour which is sometimes associated with the prolonged administration of arsenic. On Decenibei- 10, 1887, the child was admitted into the Adelaide Hospital (the Children's Hospital being at the time full) under my care, ■whilst I had charge of Dr. Verco's wards. Her condition was now truly pitiable, as there had i-ecently been a much more exten.sive eruption than had ever occun-ed before, the l)ody being covered with ruptured bulhe, which were discharging ])rofusely, the abdomen especially presenting an almost unifoi-mly excoriated surface, whilst a few unruptured blebs were to be seen on the face and limbs ; there w^as moderate pyrexia, ranging from 99° to 102°, with great restlessness and delirium, and one was struck with general reseml)lance of her condition to that of a ))atient suffering from a severe scald. The excoriated surfaces were dressed with iodoform and boiacic acid ointment, and the administration of Fowler's solution was at once commenced, in doses of m. ij. increased by December 18 to m. vijss. thrice daily. This time, liowever, the drug made no impi-ession upon her, profu.se diarrhoea and later on vomiting set in, and she died of collapse on December 24. Unfortunately, there was no ])ost-mortem examination. Various drugs, chiefly combined with oiiium, were al.so administered to combat the diarrhoea and exhaustion. The only comment I would offer on this case (and J am quite aware of the proverb qui s'excuse saccuse) is, that in my opinion the fatal result was neither caused nor accelerated by the arsenic. The child's condition on admi.ssion, and the severity of her constitutional symptoms, Mere such as to warrant the belief that she would die from exhaustion, 970 INTERCOLONIAL MEDICAL CONGKESS OF AUSTRALASIA if only from want of sleep, in a veiy short time. Moreover, she had benefited on so many occasions previously from the administration of arsenic, and in much larger doses. The other symptoms of arsenical poisoning, except the gastro-intestinal irritation, were absent ; and all writers agree, apparently copying their remarks from the cla.ssical work of M. Hardy, that diarrhcea is a fre(|uent complication, and indeed the usual cause of death in chronic pemphigus ; and they have gone so far as to mention bulla? of the gastro-intestinal tract, although M. Hardy states that these have never been demonstrated to exist. He himself, however, describes redness and ulceration of the mucous membranes. A NOTE ON THE NEW ZEALAND BIRCH ITCH. By D. COLQUHOUX, M.D. Lond., M.K.C.P. Loud., Dunedin. In April, 1888, while staying a few days at Lake Te Anau, Mr. Richard Henry, who has lived in the district for many years, spoke to me about birch itch. Mr. Henry has worked at the natural history of the locality for many years, and has had to spend a great deal of time in the bush, much of which is composed wholly of the New Zealand birch (really a beech). The disorder was a new one to me, and none of the medical men to whom I have spoken of it could give me any information about it. Mr. Henry has given me the following account of his experience of it : — " I made acquaintance with the birch itch while camped on Mani- pouri plain, eight years ago. At tiist I atti-ibuted the intense itching to the after-effect of sandflies, l>ut I soon found I was wrong. On j)arts liable to friction from the saddle, or while working, I felt the itch most severely — the ankles, toes and wrists, and especially the parts between the thighs, itched most intolerably. t heard of birch itch, and suspected I had caught it. I consulted an old resident — a run-holder — who I heard was afflicted with it every summer that he remained in the district. He told me that it always left him when he went to town. I tried to cure it with kerosene, turj^entine, painkiller, and sulphur ointment, all to no purjiose, Ijecause I had allowed it to get a good footing, and had not persevered enough with the sulphur. During the day I was comparatively at ease, but at night, when I went to bed, the itching was something horrible, so much so, that on one occasion I got out of bed at 11 o'clock at night, and plunged into the creek. This gave me relief and a clue to a si)eedy cure, wliich I attained by the application of dry sulphur and frecjuent bathing. Now I get seveial attacks every summer, l>ut witli the above treatment it causes me no inconvenience. Only about one person out of every ten is ever attacked, even when they are working and living together; and while one may be attacked exclusively on the limbs, another may be so on the body. Many people deny that it is caused by a parasite, but maintain that it is in the blood, and can be cured by change of air and diet ; but I cure it several times every year, and last year I watched A NOTE OX THE XEW ZEALAND HlliCII ITCIi. 971 it SO closely, tliat it only succeeded in forming one little spot on iny ankle, which was a great contrast to my experience of 1880. I am most liable to it in very dry weather, when about rotten wood, or among the peat moss, I also suspect that it attacks horses and dogs in a slight ilegree. ^ly first notice of it is an indefinable and luiiocalisalile impression of something moving on the skin. On looking at the place the skin seems redder, which may be caused by friction, and there is always present black dust of various shapes and sizes, a supply of which must be in the clothes, for no matter how often I brush it away it is there again. This dust I take to be the parasite or sjjore, and that not one in a thousand penetrates the skin; but that when one does so it irritates a large surface, because after a few days a pimple comes out here and there, but nothing in proportion to the surface irritated. A slight hot itchy feeling is always present, but periodically more intense, especially in the evening. Un one occasion T was on an expe- dition without sulj)hur, and caught the itch on my ankles. I put away the socks I wore for a week or two, and then put them on again, when I felt the itch again, which must have remained in the socks all that time. T am almost certain that horses sufi^er from it, but as it causes no loss, it is taken no notice of. " It has been cold anout his fingers and face. Afterwards, he could not ent^r a bireh forest without being attacked by the itch. This, he said, was a general rule- — once attacked, a man is always liable to it. He thought it was most easily acquired in 8i>riiig, but was also tionblesome, to those sensitive to it, at other times. It was most troublesome when the birch was much handled, especially if wet. He 972 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. ]iad seen it mostly about the fingers, but it also attacked the face and body, if neglected. It nearly always goes away on removing from the neighbourhood of birch forests, but as most peoj)le use sulphur internally and externally as well, its cure may be due to this treatment. I have not seen any cases during the acute stage, but in the stage of recovery the condition is such as might be found from many kinds of skin irritation. I examined the scrapings sent to me by Mr. Henry very carefully, but could find nothing but e{)ithelial debris, and small fragments of vegetaltle tissue. The cause of the disorder is therefore still to be sought. It may be a vegetable poison, like the poison oak or dogwood of the United 8tates, or it may be an acaius. In the absence of definite proof in any direction, it is useless to discuss hypotheses, and I put these cases on record in the hope that some of us who ])ractise in New Zealand may have the opportunity of examining patients in the acute stage, and of studying the disorder whore it occurs. ON SOME CA8ES OF ALOPECIA AREATA, AND ITS PROBABLE CAUSES. By D. CoLQUHOUN, M.D. Lond., M.R.C.P. Lond. ' Lecturer on the Practice of Medicine, University of Otago, New Zealand. The question of the causes of tinea decalvans or alopecia areata, is raised from time to time, l)ut cannot be said to have been satisfactoinly settled. The following cases are offered fo)' consideration, as a contribu- tion towards the discussion of the subject : — W. F. M., aged 26 years, a strong athletic young gentleman, consulted me in October 1887. He had previously been under my care for rheumatism, from which he had entirely recovered. A few weeks before seeing me, he had noticed a bald patch by the side of his head, and when I .saw him he had three well-defined and characteristic patches of alopecia areata on the scalp behind the ears. His health at this time was as usual excellent. I examined scrapings from the skin and adjacent hairs with the microscope, but failed to find any parasite. He i-ecovered in the usual way, after the application for some time of cantharides. Since then, he has had another attack of alo})ecia, which yielded quickly to the same treatment. His family history is the chief point of interest in this case. His mother died of Bright's disease, aged about 50 years. His father has for many yeai-s suffered almost constantly from psoriasis of the face and neck (the condition of the neck would be better described by the term ichthyosis). A sister, aged 15 years, has been under my care for seborrh(ea of the head, and psoriasis, and also for alopecia areata. A bi-other, aged about 2-4 years, residing in Sydney, had about the same time alopecia, involving nearly all the hairy surfaces. A brother, aged 17 years, residing in Dunedin, had several patches of alopecia ai'eata on the scalp. A sister, aged 21 years, has had fre(pient and severe attacks I SOMK CASKS OF AlJtI'ECIA AREATA, AM) ITS Pi;0I3AIiLE CAUSKS. 97,^ of chlorosis. His graiulfiitlioi- ;ind great graiulfatlier were siiljject to seAere attacks of gout, wliicli iii its ordinary forms has not attacked any of the living members of the family. All tlie brothers and sisters were as a rule healthy and vigorous, but they were all distinctly of the neurotic type. Joseph R., aged 7 years, was l)rought to me on August 9, 1888. He had then three patches of alopecia areata on the parietal and occipital regions of tiie scalp. These had existed for about three months. His general health was fair. He had an attack of pleurisy at about the time of theii- tirst appearance, from which he made a good recovery. No accui'ate family history could be obtained, but his mother had suttered from eczema of the hands oti'and on for many years. Miss N.. aged 22 years, consulted me in October 1888. 8he had then two patches of alopecia areata, situated syiimietrically behind the ears, at about the margin of the hairy scalp. She had to leave England some years ago on account of severe attacks of bronchitis every winter, and sufters much from neuralgia of vai-ious branches of the fifth nerve. There is a history of phthisis in the family, and lier mother informed me that many of hei" relations suffer from gout, but so far as she knows, none of them have ever had skin disorders of any kind. Except for the tendency to bi-onchitis, the patient altliougii delicate and easily tired, is of fairly sound constitution. At the International Medical Congress held in London in 1881, a discussion on the causes of alopecia areata was introduced bv Dr. Liveing, who said that a belief in the parasitic nature of alopecia areata was still widely entertained, and stated that the theme of his paper was, that the clinical features of the disease cannot be explained on the parasitic hypothesis. He called attention to the great tendency of the disease to recur, to its slight yet notable tendency to appear in different members of the same family, and to its association with nervous disturbances. In the discussion which followed his paper, the balance of opinion was against the parasitic theory, and some striking instances wei'e given of the association of the disease with various neuroses. On the other side. Dr. Vidal of Paris, Professor Hardy of Paris, and Dr. Thin of London, adhered to the paiasitic origin of the disease, at least in some cases, and cited examples. Pi-ofessor Simon, ()f Breslau, thought the examples of contagion adduced might be explained on the hypothesis, that there are tw^o distinct diseases Avitli the same general features — one a trophoneurosis, the other a contagious disease. Dr. Pye Smith, writing in " Fagge's Practice of JNledicine "' on the subject, says that he has no doubt the disease is not parasitic nor contagious, and that he can see no sufficient evidence that it is a trophoneurosis. In the discussion mentioned, no special attention seemed to have been given to the association of alopecia are^ita with other skin disorders, or with gout. The influence of gout, in producing irritable mucous membranes and skin troubles, is well known. That it has this effect through the medium of the nervous system is probable, and I am inclined to think that in two of the cases I have cited, the alopecia areata may have been due to ancestral gouty taint. In the case of the child, there was no evidence of gout in the family. Here the only 974 INTERCOLONIAL MKDICAL CONGRESS OF AUSTRALASIA. possible co-rehited disease, ;iscert;iiiied to liave existed, was tlie eczema of the motJier, which may or may not Jiave been gouty. In all the cases I ha^■e mentioned, I think tlie parasitic theory may be excluded, and tliat the disease was due to some inherited predis- position is particularly plain in tlie M. family ; in the case of the brother who was suiiering in Sydney from alopecia, while his brothers and sisters were attacked by it in Dunedin. Although T detected no special anai-sthesia in any of the cases, they were all very tolerant of canthar-ides. There is still sufficient rloubt as to the actual cause of the disease, to make it worth while incpiiring in such cases, as to the occurrence of other skin disorders in tlie same individual or in relatives, and as to gouty predisposition. In the meantime, it seems to me that the evidence points to the disease being one of disordered nerve function, and that to describe it as a trophoneurosis is convenient, and probably correct. We must, liowever, look to increased accuracy in describing and recognising minute clianges in the peripliei'al and central nervous -system, for an exact patliology. NOTES (m SOME SKIN ERUPTIONS COMPLICATINCx URETHRITIS. By R. A. Stihlin.;, 3I.B. Melb., L.R.C.S. Ed. The lialsamic eruptions which head the list have been omitted, although I find that in notes of over 1000 cases, treated both in dispensary and private practice with copailja or cubebs, there were no less than IGO who showed the well-marked papulo-erythematous blotches, bright red in colour and ^'el•y irritable, with the copaiba odour of the skin. Santal oil, although it produces the backache and gastric derange- ment common to the action of all these nauseous drugs, has, in my experience, in only one instance been responsible for a rash on the skin. The patient was suffering from the arthritic form of gonorrhceal rheumatism at the time, in both knees and one ankle-joint. The rash consisted of rings of a rose colour, about half an inch in diameter, not attended with itching, nor any perceptible elevation of the skin. Apart from these medicinal eruptions, I have seen, on a few rare occasions, a form of acute eczema, which was coincident with the gonorrluea, and which seems to bear out the sui)position that the absorbed poison not only attacks the joints and other serous sti'uctures, but at times may, in certain constitutions, expend its effects upon tlu! skin. The following histoiy of a case of acute erythematous eczema is an example of idios^aicratic dermatitis : — Mr. D., set. 24, robust and healthy, consulted me in November 1887, suffering from a first gonorrlia^a, and was ordered a mild alkaline mixture and injection. About a week after its onset, he noticed round the pubes a diffuse redness, not itchy, but weeping copiously, and extending up the NOTKS 0\ SOMK SKIX EKUPTION.S COMl'LICATIXCi UKKTHKI'l'l.S. 975 trunk to the level of the eusiform cartilage, and down the tVoiit and inner surfaces of the thighs. He liad never sutiei-ed from skin disease before. There was no trace of scaljies or pediculi, noi- any histoiy of gout or rheumatism. The extent of the eruption and its position for- bade one to attribute it to the irritating etiect of the discharoes. Under exclusively local treatment, as recommended by Balmanno Squire, the disease disappeared, after lasting about ten days, the treat- ment for the urethral trouble being continued at the same time. In October of this year (1888) he again contracted a discharge, and within a few hours of its advent, another attack of eczema, Avhich was much moi'e prolonged and extensive than before. Cases of fugitive erythema are not infrecpiently met with in those wlio have been treated fi-om the tirst l)y injections. They have one distinguishing feature from the dietetic and medicinal rashes in this that they occur in success! \e crops. P;i]Hilar eruptions clustered together upon a very slightly iiiHamed portion of the skin, and due possibly to the depressing influence of the disease upon the nervous system ; for in the cases noted, 1 have rema)'ked that the persons were of a highly neurotic temperament. (Tonori'hd'al lichen is distino-uished from the ordinary disease by the itching being much less severe, and by being circumscribed, with well-detined outlines. It is, perhaps, most often found in tho.se sutlering from a chronic gleet, and l^roken down in constitution ; and a very favourite seat is the front of the abdomen and chest. These eruptions are not to be mistaken for those pi-oduced by woollen clothing, from which they are quite distinct, as I have at times found them on the forehead and limbs. Finally, T may di-aw attention to the veiy rare but occasionally undoubted cases of gonorrhcca-syphilis, tirst described by Hutchinson cases where, without urethral chancre, or any evidence of chancre else- Avhere, but with merely a nmcous or muco-purulent blenorrlw^a • where even with minute endoscopic examination, notliing in the shape of a specific lesion can be discovei'ed, and in which, unattended by bubo or other adenopathy, the disease runs the ordinary course, attended with cutaneous manifestations not distinguishable from the well-known syphilides. Since writing the above, I find tJiat ^I. Mallet, in the Revue de 2Inlicine (1886), has written an able article on the subject of cutaneous diseases in gonorrhoea. He rejects the pyjemic and reflex theories of the origin of gonorrheal rheumatism and skin eruptions, and aroues strongly in favour of the absorption of a specific gonorrlueal virus which, in the light of the discovery of the gonococcus — not only in the urethra and its discharges, Vjut also in the synovial meml)rane of inflamed joints — seems to be the most likely explanation. Mallet classifies three groups — (1) Eruptions clo.sely resembling scarlet fever or measles, comin^ on late in the decline of the disease. (2) Rashes described as those of polymorphic erythema. (3) Purpuric patches. 976 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. N0TE8 ON A CASE OF LEPROSY. By F. Peipers, M.D. M. A., fet. 30, native of Sydney, of Jewish descent ; no hereditary taint of skin disease known. Five sisters and two brothers living, who have not evidenced any disease of the skin. From his eighth until his fifteenth year he lived in New Zealand, and then left for Melbourne. In 1878, he acquired gonoi'rhtea. In 1879, after sus- picious connection, he had a feverish disease for three weeks, which was called typhoid. Soon afterwards, there was fever and pains all OA"er the body, swelling of the face, nose, ears, feet, &c. There were red inflamed spots on the dorsum pedis. At no time had he ulceration on the penis, or parts tliereabouts. At that time his disease was pronounced to be sy[)hilis. After that he was under specific treatment of every kind by several practitioners, including mercury on seven occasions. "When iodide of potash was given, the symptoms were exaggerated. Arsenic, iodoform and sarsaparilla were given in large quantities. The local lesions in the throat and tongue were treated by ai'gent. nit. and hydrarg. nit. On examination, I found the hair on the head black, strong, with scalp visible at vei'tex. On tlie forehead, particularly on the right side, there were a number of swellings, large and small, varying from the size of a three-penny bit to a florin. The swellings did not penetrate to the osseous structures beneath. The elevations presented an umbilicated appearance, and were liaised somewhat distinctly at the edges. Tlie epidermis between the swellings was apparently healthy. There was no ulceration about the forehead, but a peculiar oily brownish appearance of the diseased parts was oliservable. Similar tumours existed on the ears, cheeks, lips and nose, forming together a general enlargement and disfigurement of the face — in fact, constitu- ting the true typical facies leontina. Some of the masses were idcei'ated. On the arms, wrists, legs and hands particulai'ly, the same state of things was to be seen. The skin on the Angers and toes was veiy much ulcerated, in parts laying bare the tendons. Remarkable symmetiy was exhibited by the disease in both hands, and in the feet too. A deep brownish discolouration, sharply defined from the healthy skin, was to be observed on both sides of the sternum, extending to a line corresponding with the umbilicus. The tongue showed at the tip a flat ulcerated surface, in size about tliat of a sixpence. Deep fissures, intersecting, covered the tongue. Tlie uvula was ahnost entirely obliterated. A deep fissure extending into the pharynx on the left side of the uvula was clearly distinct. A localised anaesthesia seemed to be present in the left thumb. The internal organs, as far as is known and could be traced, were apj)arently healthy. Since 1885, and up to the present, his appearance has greatly changed, the swellings in most parts having entirely gone. Lar^e cicatrices now cover the forehead, cheeks, ears and nose, some of them contracting to sucli an extent that difficulty is found in opening the nioutli. Part of the nasal sei^tum has been destroyed. Anchylosis is taking place in some of the finger-joints. An alteration in the I A CASE OF ICHTHYOSIS. 977 cliaracter of tlie skin on the chest and abdomen has taken place. However, on the back a similar discolouration is now e\'incinf>- itself. Unfor-tunately, the condition of things in the throat appears to be tending towards a worse state. It may be mentioned that an amesthetic state is being developed in the inferior extremities. The diagnosis is somewhat open to discussion ; but considering th.at, firstly, the bones have not at any time been affected, excepting the nasal septum ; secondly, the absence of improvement under strong and repeated anti-syphilitic treatment ; and thirdly, the decided cliange for the better from the exhibitioji of other remedies, we are precluded from considering the case as one of syphilis in any form. What is the disease then? The appearance of the patient, allied with the changing symptoms, indicate le})rosy. He was put uiider arsenic and (|uinine, combined with chaulmoogra oil. No improvement following, lie was then put on ichthyol, with almost immediate effect. Soon after-, the supply of this remedy ran out, and at once it was noticed that the symptoms became worse. He is now under the influence of ichthyol for tAvo years, on and off. A singular feature about the drug is the disagreeable symptoms suffered by tlie patient should it be suspended for a few days, a distinct exaggeration of the disease, occurring. The markedness of the symptoms in this case, peculiar as they are to a disease so far unknown amongst any but Orientals in Australia, renders it one of a highly interesting nature. The success that has attended the use of ichthyol in this case is very suggestive, however incomplete in its results, in a disease which at all times has presented such intractability to any and e\-ery form of medication. A CASE OF ICHTHYOSIS. By J. P. Hyax. Chevalier of the Legion of Honour. Surgeon to the Skiu Department of the Melbourne Hospital. Surgeon to the Victorian Eye and Ear Hospital. Lesser, in " Ziemssen's Cyclopaedia of Medicine," defines ichthyosis as a disease characterised by hypertrophy of the epithelium, with deposit of pigment between the lamella; and elongated papilke, and without change in the corium, beyond pigmentation of its superficial layers. Malcolm Morris defines it as a congenital hypertrophic disease of the skin, characterised by increased growth of the papillary layer, with thickening of the true skin, and the production of masses of epidermic scales. I think a majority of dermatologists will differ with him about thickening of the true skin. Most generally it makes its first appearance within a year of the child's birth, though it may 2k 978 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. be delayed to the third or fourth year. It is frequently hereditary, and by most authors it is looked upon as incurable. Tilbury Fox makes out four degrees of it : — • (1) Xeroderma, its least expressed foi-m, where the skin is rough, hard, and dry, with a tendency to furfuraeeous desquamation. (2) I. nacree, or nitida, in which the scales are large (mother-of-pearl like), and arranged in little polygonal patches — the true fish-skin. (3) In this variety, the epithelial accumulations form little square masses, somewhat dark in colour, from exposure to dirt, or from pigmentation. (4) I. hystrix, or spinosa, the papillary ichthyosis of Dr. Copeland, in which the epidermis is greatly hypertrophied, and forms a " series of closely packed horny mobile excrescences, which are usually of a dark olive-brown colour" (B. Squire), the discoloration being partly due to increased pigmentation, and partly to dirt. The so-called "porcupine men " were aftected with this variety. The disease may be local or general. In either case there are parts, as the front of the knees, back of the elbows, ankles and axillje, which it favours. Even when general, according to Balmanno Squire and Tilbury Fox, it avoids the palms, soles, eyelids, flexures of the joints and genitals. In the case which I am about to bring under your notice, the disease displays itself mainly as ichthyosis hystrix, though some of the patches, such as those which occur about the elbows, wrists and ankles, belong to the third variety described above. H. F., 5 years old, is a fairly well nourished, and, excepting for the skin disease, a healthy boy. At birth he was clean skinned, like the other children of the family, and there are ten of them. He was vaccinated when 4 months old, and it was only towards the end of the first year that his mother noticed what appeared to be a patch of dirt on the back of his neck. It began to thicken and grow, other patches came out on various parts of the body, and in a few months the con- dition of the eruption, and its arrangement, were almost the same as they now are. The family history is good. The fatlier and mother and the other children are healthy; the grandparents on either side have not suffered from any chronic skin complaint, nor is there any history of syphilis. The boy's hair, nails and skin, excepting only the affected localities, are normal in appearance, but behind both ears are scars, which his mother states wei'e caused by kimps, which he had there when he was two years old, having been lanced by a medical man. The disease for the most pai-t affects the left half of the body, for on the I'ight side are found only a few brownish stains on the ribs, and some thick scaliness about the elbow, back of hand, below the knee, and about the ankle .;ind instep. The distribution of the disease on the left side is as follows : — On the back of the neck, touching the mesial line, is a patch of I. hystrix, al)out two inches square, connected by lines of dull coloration, and some roughness on the side of the neck, with two smaller patches of the same in front just above the sternum. A mild form of the same affects the front part of the shoulder and axilla. There are some streaks of 4 i II i I ^s^ CASE OF ICHTHYOSIS (Dr. J. P. Ryans Paper.) A CASE OP ICHTHYOSIS. 979 (lull brown colour on the IjaL-k ; a series of curved streaks on tlie lower ribs, the convexities directed downwards, and some vertical streaks on the tlank, groin, and side of scrotum, where the roughness and papillary hypertrophy are more apparent. This is continued along the perin;eum and between the buttocks. Then occupying the lower pai-t of the left buttock is a large irreijular patch of Aery pronounced T. hystrix, ending in the upper third of tliigli, but joined by a streak of discoloration to another elongated patch of the same kind crossing the popliteal space, and terminating near tlie middle of the calf. There is also a little roughness and discoloration on the front of the knee, on one shin, and about the ankle. There is not, nor has there ever been, heat, itching, or other local irritation. Ft will tlius be seen that, in the subject under notice, the disease presents itself under three aspects, viz., (I) as dark brownish staining, undoubtedly due to deposit of pigment ; (2) as little squarish slightly raised scaly masses : and (3) as ichthyosis hystrix or spinosa, so gi-apliic- ally described Ijy Xeligan. He says : — " The affected sui'face prei^ents a singular and remarkable aspect, being of a greenish-ljrown colour, and so hard as to feel like horn, and to produce a grating noise when the hand is passed quietly over it, yet more or less elastic and yielding when pressed. The diseased epidermis is firmly adherent to the derma, and if attempted to be torn off with the nail, the part on which it is attached bleeds, and is painful. The spiny elevations may be separated from each other, when it will he seen that they are of a greyish or yellowish-white colour."' He has lieen under the care of several medical men, but he lias never received any benetit fi"om medication. T employed inunction Avith chrysophanic acid ointment (gr. xx. to jj) on a few of the less developed patches, but apparently without benetit. I therefore deter- mined upon trying a more radical mode of procedure, and Dr. Lalor, of Richmond, having administered chloroform to the boy, on December 20 I operated on the patch occupying the popliteal space. T tirst removed with a curved scissors tlie spinous-looking outgrowths : then I removed the skin in its entire thickness from the upper half, and with a Volkman's spoon thoroughly scraped away the affected tissue from the lower half of the patch. The result, so far, appeai-s to be favourable. The wound, as you see, has healed, and the scar is not very fomuidable looking. T propose to deal later on with the other patches Ijy erasion alone, which I think will be sufficiently effecti\e, and the scarring from which will be very .slight. Dr. G. A. Syme, who kindly examined under the microscope some of the affected tissue, reports of it : — " A vertical section shows great hypertrophy of the horny layer of the epithelium ; tliere is hai'dly any change in the papilhe or hair sacs, and no sebaceous or sweat-glands Avere found." An examination of a horizontal section shoAved the same appearances. There are some points of exceptional interest about this case. First, it is evidently not Iiereditary, none of the relations on either .side having ever had anything similar to it. Then it is found for the most part upon the left half of the body, and is closely associated Avith the distribution of certain nerves, viz., cervical, intercostal, ilio-hypogastric, ilio-inguinal, and lesser sciatic. The flexures of the joints and the 2k 2 980 INTERCOLONIAL MEDICAL CONfiHKSS OF AUSTKALASIA. genitals are affected, which is unusual ; and the skin, excepting only where the disease is found, is perfectly normal in appearance and in function. Pigmentation is a marked feature, and in some places foi'nis the only factor of the disease. Recovery is very rare. Only two cases are reported by Hebra, one of which disappeared after an attack of measles, the other after var-iola. Neligan records three cases in children under eight years, in whom the disease was confined to the extremities, which recovered under the use of alkaline baths, and the internal administration of iodine and iodide of potassium. The record is unsatisfactory ; it leaves us in the dark as to the phases under which the lesions presented themselves, and therefore we do not know if the disease was mild or tlie reverse in character. I do not know if the treatment which T am pursuing has been employed by others ; at all events, I have not seen any account of it. SECTION OF DISEASES OE CHILDJiEN. PRESIDENT'S ADDRESS. F,y AV. Snowball, M.B. et Ch. B. Melb., L.R.C.S. Ed. Surgeon to the :Melbounic Hospital for Sick Children. On Intestinal Tuoublks in Ciiilduen. Gentlemen, — In olioosing the title intestinal trouble in childhood, as a subject for discussion at this meeting, I have been influenced by the fact, that of all children's ti'oubles, abdominal ones are in this country the most frequent, and I am sorry to say in many cases the most unsatisfactory as regards the result of treatment. Of all children's complaints at this period of the year, the most frequent and most fatal is the gastro-intestinal. In fact, it may with justice be looked upon as an epidemic, or rather if I may be allowed the expression, as an epidemic of sporadic cases, for as yet there does not appear to be evidence that the cases liave any direct power of contagion. In this, our climate is more like that of the Amei'ican towns, where, in the hot period of the year, the same condition seems to exist aanong the children, specially in the cities, that we find here. The principal factors in the pi'oduction of these complaints are heat, hygiene (or ratlier tlie want of it), food, age. Certainly, high temperatui'e plays the Diost important part in this direction, not only tending to produce febrile disturljance in the child, but also tending to cause fermentative changes in the food, in the case of an artilicially- reared infant. Tliough in hot weather all places are more or less subject to a visitation from the complaint, the crowded towns are most subject, next come inland places, especially if flat and badly drained. The mountainous parts, ;ind places close to the sea shore escape the best, though some of our over-crowded seaside sul)U7'bs are specially sul^ject to it. Food.— As in the case of most other ailments, artiflcially-fed children are more prone to be attacked, than are tliose who are reared on breast milk. This is due to the facts, that these children appear to lia/e weaker vitality than the nursed ones, and so ha\e less resisting power against disease; and also that their food is more liable to fermentative changes than is breast milk. 982 INTERCOLONIAL MEDICAL CONGKESS OF AUSTRALASIA. The age most affected is under two years, that being the period of greatest activity in the intestinal glands, which, being in a state of unstable equilibrium, are more likely to be disordered than at a later period. Any part of the alimentary tract may be affected. Genei'ally the stomach is involved, and in some cases the disease does not appear to extend further, the ease either recovering or dying from exhaustion before the bowel is affected. Next comes the small intestine, and, in the more protracted cases, the most definite lesions are situated in the ileum, especially near the ileo-ca'cal valve. The symptoms vary with the part of bowel affected and with the stage of the disease ; one point of interest being that as in intussusception, tlie higher up the lesion is, the more proliably will there be more or less complete suppression of urine. The terminations of the complaint, are in favourable cases, recovery without any sequeUe, beyond intense weakness. In others, tlie supervention of that condition of asthenia known as spurious hydi'o- cephalus, or the hydrenceplialoid disease of Marsliall Hall, Avhere all the symptoms of tubercular meningitis are present, except that the heart is feeble and uncertain in its action, the extremities are cold, the fontanelles depressed, and passive cerebral effusion may take place from venous stasis, due to want of propelling power of the heart. Another class of case terminates in ur;emia. Here you find the diarrhoea and vomiting ceasing. Nourishment is taken eagerly, but the urine is nearly suppressed ; generally, muscular twitchings set in, sometimes violent convulsions, amidst which the patient sinks. One of the most common of all terminations is that condition of ill-health known as marasmus, popular! 3^ called consumption of tlie bowels ; which, though widely difterent from tabes mesenterica, presents all the symptoms of it, except that the mesenteric glands, instead of being enlarged, are generally more or less atroj)hied. As regards treatment, during the last twenty years it may be divided into three difierent epochs, the first being the eliminative period, when the endeavour was to e\'acuate the materies morbi by means of purgatives ; the second, wlien sedati\'es played the most important part, and wlien at all hazards it was sought to ari*est tlie peristaltic action by means of sedatives and astringents ; and the third, wliich exists at the present time, that of antisepsis, the materies morbi being killed, if possible, by the introduction into the system of the various germicides. Possibly all aie more or less right, and the happiest results Avill l)e ol)tained by a scientific combination of all three methods. president's address — SECTION OP DISEASES OF CIIILDRKN. 983 The method I usually adopt t'of a case of gastro-intestiual catarrh, if seen in the early period, when the temperature is high, and gastric symptoms are most prominent, is to put tlicciiild in the coolest and best ventilated I'oom in the liouse ; if possible, keej) the temperature of the room down to G5°. Wrap the child in cold lotion to lower the body heat, and stop all food except icefl rice \\at('r, and iced brandy and water, in small quantities, gi\-en frequently : if the child is at the breast, recommend that the breast be emptied by })umi)ing before the child is put to it, so that it may have the comfort of sucking the nipple, without the irritant of the mother's milk, which in these cases is more than the stomach can bear. As for drugs, I have most confidence in minute doses of calomel, say gr. Jj, repeated ever hour till a grain has been taken ; if tliat fails, creasote and hydrocyanic acid in hourly doses, for from six to ten hours, and my experience is then that either the cliild is better, or else that the disease has progressed, and that intestinal trouble has commenced, as sliown by the frequent, watery, foul-smelling motions, with coiisiderable pain. I then use one of the liquid bismuth preparations, with liquor hydrarg. perchlor., and if there be any sign of heart failure, an occasional dose of digitalis. If the symptoms do not then abate, but purposeless straining comes on, with the passage of mucous stools streaked with blood and great tenesmtts, I apply belladonna over the bowels, at the same time giving one of the insoluble bismuth salts, such as the subnitrate, with full doses of opium, at same time giving injections of various astringents with sedatives, the diet at this time consisting of raw albumen, raw meat juice, and brandy. If in spite of treatment the case goes on to the hydrencephaloid state, J wrap the child in brandy and oil, apj)ly nmstard to the heart, give stimulants, such as spirit, amnion, aromat. and digitalis, and tether, oi" camphoi'. In the unemic cases, I have nothing more useful than small doses of pilocarpine, say J-^ gr., with digitalis and warm mustard bat) is. If the case goes on into marasmus, the changes may be rung on all the various digested and soluble foods, with varying amount of success. But, in all stages of the com|)laint, the two main features for a suc- cessful issue are — removal to a healthy locality, and the stoppage of all food that requires any digestion. Milk, no matter of what kind and how prepared, whether human, whether peptonised, does positive harm in the early stages. 984 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. GASTRO- ENTERITIS IN CHILDREN: SOME POINTS IN PATHOLOGY AND THERAPEUTICS. By D. COLLINGWOOD, M.D. This name may be used to indicate a class of diseases, the wide- spread prevalence and importance of which are my excuse for asking your patience for a few minutes to-day. Those of us especially who are connected with institutions where children are brought into the world, reared, or where their diseases ai'e treated, must all feel that in this section, more perhaps than in any other, the value of an inter- change of ideas cannot be ovei'-estimated. Classification. Of diseases of the gastro-intestinal tract we may make a classification as follows : — Acute gastric catarrh, chronic gastric catarrh, dyspepsia, acute intestinal catarrh, chronic intestinal catarrh, cholera infantum, dysentery or ulcerative colitis, tubercular enteritis, parasitic enteritis. I do not propose to attempt to travel over so wide a range of material as this classification otters, but selecting from it that which appears to me to be the most prevalent form in these colonies, I wish to offer a few remarks on what I may call gastro-enteritis. Etiology. Amongst predisposing causes we have season, age, locality, heredity and social condition ; and undoubtedly here, as in England and America, summer, especially the earlier and later months, is the period of the year when the disease amounts almost to an epidemic. Hot damp weather is certain to be followed by a large increase in the number of our gastro-enteric patients ; and most of all so v/hen the nights are muggy and hot — when even healthy children are broken in sleep. High barometric pressure would seem to have some influence, especially when associated with excessive moisture in the atmosphere, more so than high thermometric indications. Locality and social conditions may be taken together. Overcrowding, inefficient hygienic surroundings, tilth, bad ventilation, etc., are the outcomes of cities and po\ei'ty, and potent are their evil influences upon the infant exposed to them, both as predisposing agents and as direct exciting causes, because for similar i-easons the feeding of such infants is as bad as the hygiene. Heredity is not usually introduced liy the text ])ooks as a pre- disposing cause, but apart from the inlluence of sun-ounding conditions to which the children of such parents are exposed, the propagation of their species by ill-nourished, strumous, dyspeptic parents, must necessarily produce Ijeings with prejudiced alimentary mucous mem- l)ianes, and ill-acting absorbent and glandular systems. Of direct exciting causes, bad feeding comes first. Let me divide this into two classes : (1) the character of the food, (2) the method of feeding. No one who has taken tlie trouble to look over his case book can have failed to notice how comjiaratively rare gastro-enteric disease is in the nurslings of averagely-healthy parents, how enormously GASTRO-EXTKIUTIS I\ CIIILDUHN. 985 it preponderates in hand-fed children ; so tliat one is conipelhid to the conviction that all hand-feeding-, however well-directed, is bad. Next to hand-feeding as a direct cause, I should place too early and too late weaning, and afterwards injudicious irregular nursing or the insistence in nursing of mothers whose own condition of health unfits them to produce healthy nourishment for their infants. [n hand-feeding, amongst bad foods must be pbiced sour milk, an undue preponderance of farinaceous st;irchy foods, excess of sugars, meat at too early an age, excess of fats and butters, scraps of adult food. By faults in the method of feeding, T mean in nursing, that want of regulaT-ity which it is so hard to persuade mothers to avoid — -the yielding to the temptation to put the child to the breast whenever it cries ; and in hand-feeding, the same irregularity, as well as the want of scrupulous cleanliness. Amongst other exciting causes, we have cold, thi-ough insufficient clothing in weather when perspiration is constant ; acute diseases, especially the exanthemata. Symptomatology. There are usually some premonitory symptoms of these complaints, lasting over two oi" three days. They consist of restlessness, fretfulness, disturbed sleep, the infant waking with short tits of crying, pallor of the face, heat of the liead, impaired appetite, and obvious discomfort after food. The actual attack is ushered in with vomiting and purging, usually in this order : — The vomited matters consist of the contents of the stomach from the last meal at first, and bile afterwards, when the stomach has been thoroughly emptied by repeated retching attempts. If milk has been taken, it is rejected in sour, very acid masses, con- sisting of cui'd, often in the shape of lumps as l^ig as a walnut, and of ^■ery tough consistence. The stools are frequent from the first, and painful or preceded by pain. Their number varies from half-a-dozen to twenty or more per diem. In the early stages they are semi-solid, homogeneous, yellow in colour, and neutral in reaction. 8oon they become more liquid and green ; and later still, they ai'eacid in reaction. They may then become heterogeneous, gi-eenish with admixture of particles of yellow f;eces, and neutral in reaction ; or green and acid, with flakes of yellowish-white caseine. Further, they may, and usually do, vary from hour to hour, both in colour and consistence. Mucus or blood, or both, are usually present in the later stages. Sometimes, and this is in very severe cases, the character of the stools appi'oximates to that of cholera infantum — liquid, watery, and almost colourless; in such, these stools may Ije passed without any straining, but, in moderate cases, tenesmus is a mai-ked synqjtom. The tongue is dry, clean at the tip and edges, furred thinly over the dorsum. The fur Ijecomes thicker as the case proceeds, and in severe cases the tongue becomes dry and brown. There is great thirst, the child obviously craving for cool diinks. Ai)petite for solid food is lost more and more. Tlie abdomen is at first distended with flatus, and eructations are frequent and sour-smelling. There is often some tenderness on 986 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. palpation from the first. In the hxter stages the belly is flat, sometimes retracted, always flaccid. The temperature is raised from the first— 102° to 103° F. on the average, with slight morning remissions. As the case proceeds, these remissions become more marked, and then perspirations take place. In the last stages of some cases, great variations of temperature are noted. The I'estlessness which was present from the first continues through- out the case. It increases when there is a tendency to convulsions ; the head is then rolled from side to side ; slight twitchings are noticed, perhaps some strabismus and sluggishness of the pupils, culminating in an attack of convulsions, unilateral or general. The pulse always runs high, and early shows signs of weakness. Respiration is affected, as in pyrexia from whatever cause. A short sharp cough of peculiar character is a frequent accompaniment of the attack from its earliest stages, especially in cases where the gastric symptoms are the most prominent. The urine is diminished in quantity, high-coloured, and irritating to the skin. It is passed only two or three times daily. The general tissues are speedily affected, the roundness of the face is lost, the limbs become soft and flabby, the eyes sunken and surrounded by dark rings, the conjunctiva; lose their brilliancy, and the '• nasal line " is deepened. The position taken by the patient shows languor and weakness, a disinclination to move or be moved, but the onset of restlessness is an unfavourable sign. The skin of the buttocks and thighs soon become excoriated by the acid stools and concentrated urine ; the skin of the bod}', esj)ecially the abdomen, is dry and harsh. The progress of the case towards i-ecovery is first marked by the cessation of vomiting, by improvement in tlie colour, and diminution in the frequency of the stools, increase in the quantity of urine passed, and a re-gain, in cases of short duration, of flesh and strength, but little less rapid than tlieir loss was. When the symjitoms tend towards a fatal termination, convulsions may occur ; at other times, drowsiness comes on, possibly ursemic in character, persistence in refusal to take food, coldness creejnng up the extremities, and sometimes the cessation of active symptoms, such as vomiting and purging. Morbid Axatomv and Pathology. The primary lesions consist of hypersemia of the intestinal mucous membrane. The position in which this hypera^niia is greatest varies in different cases ; and as is usual in catarrhal diseases, the evidences after death do not by any means correspond with the severity of the sym})toms, especially if the duration of the case has been short. The lesions occur in patches, frequently over the whole alimentary canal, but most connnonly and intensely in the ileum and colon, and especially at the ileo-caical valve, and in the sigmoid flexure. The mucous membrane is. reddened, softened, and swollen, the hypertemia shows up in arborescent patches about the follicles and patches of Peyer, which stand out above the surface, and are marked with dark red spots. The arborescent injection is very visible from the peritoneal surface. GASTKO-ENTERITIS I\ CHILDREN. 987 In cases which have gone beyond the acute stage, the mucous surface is frequently abraded about the solitary gland and patches. The lesions found in the stomach do not by any means always correspond with the severity of the disease, as shown In' its symptoms during life ; the exjtlanation of this fact may depend partly upon the greater irritability of the gastric mucous membrane in children, and jiartly upon irritability reflected through the sympathetic nei've plexus from the intestines. it has been suggested also that the swollen con- dition of the mucous membrane forming the ileo-c;ecal valve, frequently so great as almost to occlude it, may have a direct agency in the causation of the vomiting. The morbid condition of the contents of the intestine is of interest. An excess of secretion of mucus is of course present in all cases, and the reaction of the contents of the small intestine, instead of being alkaline, is found to be acid. The colour too of the contents of the healthy small intestine is a bright rich yellow, or orange, but in this catari'hal con- dition it becomes green. The explanation of this change of colour depends upon alteration in the biliary colouring matters. We know that these are the parents of the colours in healthy fieces, and it has been shown that bile exposed to air, or to tlie action of an acid, changes colour by the bilirubin becoming biliverdin. This is seen in the ordinary so-called bilious vomiting, when bile regurgitates into the stomach, and is exposed there before being rejected to the action of the acid gastric juice. Similar conditions are ])resent in these ca.ses : the intense acidity of the material passed down into the intestine from the stomach — partly the result of the increased acidity of the gastric secretion, and j)artly the result of acid fermentation — proves too much for the alkalising powers of the bile and pancreatic juices and succus entericus, so the action of the acid contents changes all the bilirubin at once into biliverdin, and gives the colour to the motion so characteristic of the disease. These green motions must be cai-efully distinguished from the chopped spinach motion of chronic entero-colitis, in which the colour is probably due to altered blood-colouring matter. The pathology of the central nervous system in this com|)laint is of interest also, but I will touch uj)on one [loint only, and that is the depression of the anterior fontanelle, which is so often seen in the later stages of cases which are not improving. The explanation of this phenomenon which has been offered, is that it is due to withdrawal of the fluid elements from the brain by the flux from the bowels, so that an actual loss of bulk of the cranial contents ensues. As the bony case is not rigid in young children, atmospheric pressure from without leads to depression of the softest and least resistant parts, so that dei)ression of the fontanelle and even overlapping of the bones ensues. In prolonged cases, this collapse of the cranial vault may not be sufficient to compensate for the loss ; and a tidal wave of cerebro-spinal fluid being for similar reasons impossible or insufficient, the cerebral sinuses and large vessels become engorged with blood, the current becomes sluggish, owing partly to the engorgement, and i)artly to the enfeeblement of the heart's action, and so the conditions most favourable to thrombosis result. The superior longitudinal sinus is chiefly affected 988 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. in this way, and death results vvitli difficult respiration, stupor, dilata- tion of pupils, and other nervous symptoms. The diminution in the quantity of urine excreted depends apparently in part upon the quantity of fluid lost from the bowel ; for although in cases of moderate severity this quantity is not very great, it is sufficient to cause a reduction of the blood pressure, and so to diminish the urinary secretion. In cases where death occurs with uraimic symjjtoms, probably acute nephritis exists, the kidneys sharing in the inflammatory affection. Further investigations on this point would be of great value. The morbid processes, concerned in the formation of the large masses of curd found in the intestines, deserve soiue attention. Doubtless, the use of milk, containing too large a proportion of caseine for the digestive power and age of the infant, has much to do with it. Certainly, too, irregularity in feeding must have its influence, since it gives rise to a catarrh of the mucous membrane of the stomach, with its consequent excess of mucus secreted, which in its turn favours acid fermentation, and also acts mechanically by preventing the access of the digestive materials to the food. The increased acidity of the gastric secretion has another influence, in producing large masses of curd immediately upon the introduction of milk into the stomach, instead of the small flakes of curd which are formed in the healthy process. These masses are more liable to be formed if fresh milk be introduced to a stomach already in over-action, and containing a quantity of semi-digested milk, i.e., time not being allowed for one meal to digest and pass into the duodenum, Viefore another is given. The masses of curd so formed are too large to be penetrated by the digestive ferments, and so they react mechanically as irritants of the intestinal nnicous membrane. Microscopic examination shows them to be swarming with bacteria. Treatment. Treatment naturally divides itself into two headings — prophylactic and direct. The study of the causes of gastro-enteric troubles gives the key to the ]->rophylaxis, and by insistence upon proper care in feeding, where liand feeding is necessary, and upon an intelligent carj'ing out of the directions in general hygiene, as well as in the choice of proper foods, more can be done in prevention than medicine can do in cure. The ignorance existing in these colonies amongst parents of even tlie better classes, about infant management, is simply appalling, but is transcended by the obstinacy, far woi'se than ignorance, of the large majority of so-called nui-ses to whose tender mercies we are committing the future men and women of Australia. In tlie direct treatment, there are two points specially to be considered in I'egaid to food — (1) The food itself, (2) The method of its administra- tion. If the child be hand fed, milk being the chief aliment, to it must first be directed our attention in all cases of the disease which we are considering, and its j)ossible faults and the harm they may do must be borne in mind. (J)ur flrst aim must be to [)revent or to cure the GASTRO-KXTKl;niS IX CIIILDKKX. D89 formation of too large masses of curd, and to this end the exhilntion of lime water or other alkalies, or the process of enzymising befoie administration should be resorted to in all cases. The use of such i)reparations as nenicasei, which have for their <)bject the approximation of cow's to mother's milk, may be sufficient. In a large number of cases, the condition of things l)efore the ))ati(nt comes under ti-eatment is such, that success can only be obtained hy l)oldly cutting of!" milk altogether for a time — if not at first, at any rate when att(Mnpts to render it more digestible have failed ; barley water or rice water, and broth (carefully freed from fats), should be substituted, or one of the jirepared foods, such as Mellor's or Allen and Hanbury's, made with barley water in place of milk, may be found suitable. As soon as the ci;rds have disappeai-ed from the motion, an attemjjt may lie made to restore milk to the diet, the stools being carefully watched, and the milk cut ofT again if it passes undigested. A very convenient way of re-introducing milk, is to add it in increasing quantities to the barley water, given alone, or used in the preparation of artificial food. I think I have given sufficient reasons for urging a greater attention to regularity in feeding infants, both as a preventive of disease and iii the treatment of it. I need hardly allude to the quantity given excc-pfc to say that, in all cases of gastro-enterie troubles, the quantity must be strictly curtailed from the first, according to the age of the patient. Medicixks. I will not waste 3'our time by rei)eating the usual routine of medicinal treatment. One or two points, however, are of interest. If the child has l)een hand fed on cow's milk in any comVjination, alkalies come first in the list of useful drugs. Their action consists chiefly in neutralising the natural acidity of cow's milk, and so approximating it more nearly to mother's, and rendering it more digestible. If there be much acid fermentation going on, the administration of alkalies after food must be of use. ►Sedatives, notably o[)ium, have probably been too little used hitherto. Their use has been almost limited to the induction of sleep, and for this they have been very properly condennied. There is very little doubt that small doses of opium, judiciously given to relieve pain, must save that nerve exhaustion, which tells more seriously upon an infant than upon an adult. The best form is pulv. ipecac, co. in doses of },-'2 grains, according to age. In profuse watery diarrhoea, as an astringent combined with sulphuric acid, tincture of opium is very valuable. Mercurials have been our stock remedy from time immemorial, and yet the therapeutics of tlie drug have been very imperfectly worked out. From clinical observation, the following would seem to be the indications : — (1) That vomiting is often best controlled by small doses of the per- chloride in solution, and this form has the advantage of being very easy of administration. (2) That in diarrhcea of intestinal catarrh, small doses of l-ll grains of grey powder, or jxj~1 gi'^'ii^ of calomel, act well. (3) That the benefit from their exhibition may not be fully seen until they have been pushed for one to three days. 090 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. (4) Tliat during tlieir iulmiiiistration, the stools first regain tlieir normal colour, ancl then gradnally diminish in frecjuency. From these and other considerations, it would appear that the drug in question is a direct sedative to the mucous membrane of the alimentary canal, and esjiecially to the stomach, and that it tends to control the acid fermentation which is so powerful a factor in the disease. This effect is twofold. Under the influence of mercury, the hiliary secretion is increased- — so experiment and clinical observation ■would lead us to believe — and bile being the natural intestinal anti- se])tic, this increase would tend to check acid fermentation ; also, as bile and pancreatic fluid too (arguing from the analogy of the salivary glands) are increased in quantit}', this increase in quantity of the alkaline fluids poured out upon the already too acid material sent on to the intestines from the stomach, will tend to neutralise it, and so bring it more nearly to its natural condition. In addition to these results, the powerful antiseptic jjroperties of the drug itself must be of great value. Last of all, it appears certain, emj^irically, that mercury is a direct sedative to the mucous membrane of the stomach ; it probably continues a similar action u])on the intestinal mucous membrane — an additional I'eason for its usefulness in catarrh. In the treatment of the vomiting, creosote, especially in combination with small quantities of iodine, is of great value, sometimes checking the emesis where mercury lias failed to do so. Its therapeutics closely resemble those of mercury in its antisejjtic properties, and it has special value, which the mercury has not, in relieving the flatulence, which is a distressing symptom in the earlier stages. The sulphate of aniline is siuiilarly of particular value in distension from flatus. DISCUSSION ON GASTRO-ENTEPJTIS. Dr. Walsh (Kew) recommended the administration of hydrarg. subchlor. gr. ij at the commencement of the attack ; he was not satisfied with his experience of antiseptics in this form of diarrhwa. Dr. DYRiNfi (Coburg) believed that there was a connection between typhoid fever and the epidemic gastro-enteritis of children, often seeing cases of both affections in the same family at the same time. Dr. Davenport was dissatisfled with astringents in this form of septic diarrhcea. He had found chloral very useful in these cases, giving as much as gr. j every three hours to a child six months old. He considered that it acted as an antiseptic, sedative, and antipyretic. It was very beneflcial to send patient away for a change of climate, as .soon as the septic character of the stools cleared up. He also had been frequently struck by the apparent similarity between typhoid fever and gastro- enteritis in children. Dr. Henry believed that dentition played a large part in the etiology of gastro-enteritis. He had found Brand's essence of chicken a useful substitute for )nilk i)i these cases. Dr. NiCKOLL (Hawthorn) thought that as the reflex irritability of children was so great, the presence of the curds was a great factor in the etiology of gastro-enteritis, and so believed in the old-fashioned AN ANOMALOUS CASE OF ACtiUlRKD INFANTILE SYPHILIS. 991 •castor oil. His Excellency the Govei'nor had drawn attention to the very great infantile mortality in tiie colony; he thought it was due in great measure to the bad feeding and hot climate. Dr. Salmon (Ballarat) had found great benefit from minute doses of calomel in cases of gastritis. Chloral was most useful in those cases depending on dentition as a cause. Tee by the mouth, and ice to the abdomen, he had found very useful in checking the symptoms. Dr. CouPEK -Johnston said that the etiology was very indefinite. He had found that improper food, sepsis, and arrest of secretions were three very potent causes. Arrest of perspiration often precedes an attack of gastro- enteritis, and the arrest of the same may often be procured Ijy means of a hot bath, ;ind wrapping the child in a blanket for ten minutes after the bath, giving six oi" eight drops of brandy if there is much depression. llegularity of feeding is not sufficiently insisted upon among the children of this colony. Dr. Power thougiit that l)ad drainage, was a powerful factor in the etiology of the disease. Dr. James Robertson laid gieat stress on the diet l)eing regulated, and rest in the recumbent posture. He also believed firmly in the use of castor oil at the commencement of the attack. Dr. Dawson said that the Ijowel was inflamed, and filled with ii-ritating matter. The first indication was to clear away the ii-ritating matei-ial ; and second, to rest the bowel by suitable nourishment. He liked calomel better than oil, as it had a beneficial effect on the hepatic congestion. In reply, Dr. Sno\vi3ALL thought that the \isitors had been too polite in not condemning the foul smells of Melliourne as a very potent cause of our high infantile mortality. He i-egretted that he was unable to shai'e in the hopefulness about drugs which seemed to be entertained by most of the speakers. Dr. CoLLiNfiWOOD, in reply, laid great stress on the necessity for further investigating the pathology of gastro-enteritis in infants. He considered that milk was usually the ^•ellicle for infection, and that the sudden changes of temperature were very detrimental to the milk. He did not consider the use of iced drinks rational in the treatment of children. AX ANOMALOUS CASE OF ACQUIK1:D INFANTILE SYPHJLIS. By R. A. Stirling M.B. et Ch. B. :\l.'ll)., L.R.C.P. et S. Ed. In this case, the father, who acquii-ed syphilis three years before marriage, after rigorous treatment was pronounced free of the disease. A relapse occurred some six months after his child was born, and infection of the child followed. C. J., fet. 30, consulted me in LS82 with an infecting sore and a bubo. Under treatment with mercury and iodide, no secondary symptoms supervened. Not believing the true nature of the disease, he infected a 992 IXTERCOLOXIAL MEDICAL CONGRESS OF AUSTRALASIA. woman with clianci-e, and in her tlie secondary symptoms followed the usual course, lasting about a year, thus settling all doubt as to the genuineness of the attack. In 1885, having been treated more or less continuously the whole time, and no sign — not even a blotch on the skin — appearing, he was allowed to marry, on the advice of another physician and myself. His son Avas born at full term, and was a healthy boy. Some weeks after birth, the child developed a rash about the anus, which caused the father much alarm ; but there were no snuffles. He .slept well, was in good health, and ail signs of eruption disappeared with the application of zinc ointment. The mother is now, and always has been, quite healthy. When six montlis old, a .small sore appeared on the lower lip of the child, followed by induration of a gland at the angle of the jaw. Simultaneously, there had been a breaking out of an old sore on the angle of tlie mouth of the parent, and it was undoubtedly the contagious secretion of this sore which had inoculated the infant. A macular sypliilide, diftering in no wise from the cpmmon form of the adult, next appeared on the front and sides of the chest, and a few moist papules on the anus and between the toes. The throat was not affected, and no other symptoms arose. The treatment consisted in inunction with blue mass, and internally the hyd. c cretcu Such, shortly, is a sketch of an unusual occurrence —the child escaping infection during the latency of the di.sease in the father ; a latency brought about probably by early and prolonged treatment by hydrarg., and which goes to bear out the assumption of Zeissl and others, that in some cases mercury given at the early stage merely paralyses the activity of the syphilitic virus. I should have before stated that the child was suckled by the mother until ffve months old, and then bottle-fed A neai'ly parallel case is infection of tlie mother by a hereditarily syphilitic child. ON A CASE OF SYPHILITIC DACTYLITIS IN A CHILD. By II. A. Stirling, M.B. et Ch. B. Melb., L.R.C.P. et S. Ed. Dactylitis syphilitica is a rai'e affection, and as but few cases are on record, T have thought the following woi^thy of production, especially as I happened to be aware of the antecedents of one of the parents : — Early in 1878 I circumcised, at the Melbourne Hospital, a young- man who had an undoubted infecting sore on his prepuce, as well as a congenital phimosis ; tlie wound rapidly healed, no further symptoms of the disease became developed, and in three months from that time he married. (I may mention that in this, as in many other instances of .syphilis, neither tlu; inguinal nor any other glands were involved — tlie disease probably missing the lymphatics and entering the blood direct.) Two children were born of the marriage — a boy in April 1879, and a girl in August 1880. In 1885, the father consulted me for nodes A CASE OF SVPJIIMTIC DACTYLITIS IX A CHILD. 99:3 on the tibia, for which he had been some time under treatment Ijy a Chinese doctor, and which he of course thought to have no connection with his former disease. These nodes, which were symmetrically placed, rapidly subsided under the tannate of mercury and potassium iodide. He looked robust and well, and with this exception had been free from any symptoms. In 1886, several gunuuatous ulcers appeared on the outer and inner sides of the legs, and required a renewed and prolonged course of medicine before healing. He stated that all this time his wife was quite healthy, and had never had a miscarriage. In January 1887 he returned with his .son, now nearly eight years old, who was suffering from an affection of the fingers. I found the terminal phalanges of the digits of the left hand, excepting the thumb, the seat of periostitis and ostitis — the swelling being situated more on the back than the front, and not involving the nails. Each finger was more or less swollen along its whole lengtli, but this seemed to be due to cedema and to joint effusion, which mucii impeded movement. There was only slight redness and mottling at the ends of the fingers and at the back, and the pain was much less than in whitlow; although subsequently in the index finger there were all the symptoms of whitlow, with caries and loss of the bone — a true syphilitic onychia. The gummy deposit in the other fingers rapidly disappeared under treatment, and showed no tendency to break down. The fibrous sheaths of the tendons were not at all affected. Pressure over the ends of the fingers caused severe pain, but not at their bases. The course of the disease was chronic, owing to the condition of the first finger, which at one time looked as if amputation would be required; but in the other fingers full doses of grey powder and the iodide of potassium, with occasional inunctions of mercurial oleate on the affected part, rapidly reduced the swelling, which had nearly all disappeared in six weeks. During treatment, however, the ring finger of the right hand showed signs at its initial joint of periosteal trouble, but the symptoms passed away. One curious effect of the disease was to leave elongation and incurving of the nails. Tliis boy showed no other signs of late hereditary .syphilis ; and beyond a well-marked depression of the nasal bones, which was not present in the fathei^ and se\ei'al suspicious-looking stri;e about the angles of the mouth, I could get no history of early infection. Taylor, who has written fully on this disease, states that in its primaiy stage it is amenable to treatment ; and to this circumstance of early ti-eatment, and the peculiar features of the hi.story, I think I owe its recognition, as the swelling is not unlikely to be put down as strumous, and treated with cod oil and tonics. The points of intei'est are the innnunity for many years of the father from .syphilitic symptoms, after excision of the primary lesion — an immunity in my experience by no means unusual. The immunity of the son in infancy — no snuffles, nor wasting, eruption, or mouth-sores ; no deformity of the teeth. The tertiary character of the disease in the father transmitted to the son, as shown in the former by the large size and small number (two) of the swellings, and in the latter by the disease itself. 2s 994 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. ON A CASE OF ACQUIRED SYPHILIS IN A CHILD THREE YEARS OLD. By James P. Ryan, M.K.Q.C.P.I. Chevalier of the Legion of Honour. Surgeon to the Skin Department of the Melbourne Hospital. Mrs. A. H., aged 25 years, first caine under my notice as an out- patient at the Melbourne Hospital, on March 14, 1888. She was sufferino' from secondaiy syphilis, and had mucous patches about her lips, and on her tongue and pharynx, a dark coloured macular eruption slit^htly visible on the forehead, but well marked and widely distributed over the limbs and ti-unk, and condylomata about the vulva and anus. She was living with her husband, who was affected in a somewhat similar manner. She had been married for four years, and had one child, a girl, nearly 3 years old, and healthy, whom she brought with her when she visited the hospital. Her husband had an eruption on his skin about Christmas time, and a fortnight or three weeks later she also became affected. Previous to this, she had enjoyed good health. The child was always healthy, and had never suffered from a skin eruption. However, about the middle of May a pimple made its ai)pearance on her forehead, above the left eyebrow. A week later it had become a slightly raised flattened patch, about the size of a three- penny piece, with a somewhat depressed centre, tending to scale. It became gradually larger, until a month from the time it was first noticed, it was as big as a shilling, nearly round, somewhat raised, with an in- durated base, and the centre for a fouith of an inch was depressed and eroded. It was a good typical example of the '-parchment" chancre, the peculiarities of which, according to Jonathan Hutchinson, ai'e, " that its area of induration is large, and its thickness very small, whilst there is little or no inflammation." Two weeks later, a roseolar rash came out on her l>ack, chest, abdomen, and thighs, a few spots showing on her forehead, her arms and legs being iinatfected. About the middle of August, absorption of the chancre had taken place, and there was left only a red patch to mark its site ; the eruption had assumed a coppery tint, the j^harynx was deeply congested, and there were some small mucous patches on the tongue. Henceforward there was gradual but steady inii»rovement, and when last seen by me on November 21, the rash had entirely disappeared, the mucous patches in the mouth nearly so, and there was only left a copper-coloured stain to mark the spot where the chancre once had been. The child's general health did not seem to suffer to any appreciable extent, and no treatment was employed until the eruption was fully out, when the daily inunction of mercurial ointment was begun, and continued until October 3, after which she was put upon small doses of hydrarg. e cretii. There can Ije little doubt in this case as to the mode of infection. She was an only child, and the pet of both parents, who frequently fondled and kissed her. One of them, the mother, if not both of them, had syphilitic sores about the mouth, the child had probably some slight abrasion on her forehead, and through this the syphilitic poison made its entry. CORRELATION OP FOLLICULAR TOXSILLITIS IX CHILDKEN. 095 Such a mode of infection is certainly unconunon, tliough why it sliould be SO is not very clear, for umlonbtedly a considerable number of women having young children, amongst tlie liumlder classes in Melbourne, and amongst hospital patients, ai'e the subjects of syphilitic disease. THE CORRELATION OF F(JLLICULAR TONSILLITIS IN CHILDREN, WITH OTHER ZYINIOTIC DISEASES. By A. HoxMAN, M.R.C.S. During the last four or li\e years, I have taken notes of a number of cases of follicular tonsillitis, which have come under my care. Mv attention has been arrested by the grave results which have frequently followed those sutfering from this generally considered simple complaint. It must be observed that the vast majority of these cases have occurred amongst children and young people. The glandular activity prevailing during childhood, the well estaVjlished functions of the tonsils, and their relationship to other glands consisting of lymi)hoid tissues, such as the .solitary and agminated glands of the intestine ; the numerous instances where the disease has assumed the character of an epidemic, the per- sistent way in which it retui-ns to a neighbourhood whei'e the surround- ings are unhealthy, and the distinctive symi)toms of its course, all lead me to believe that there is a distinct relationship between this disease and others of a sej)tic character. The symptoms in all the cases I have observed of this disease are as follow :— The attack is generally sudden, and may be preceded by a ]"igor, or in some cases, especially in younger children, V)y convulsions ; in others, by wild delirium. Upon examination of the throat, there will be no sign of exudation, but the tonsils and uvula will be a deep cherry -red colour ; the temperature ranges from 10.3" to 10.5°, or higher; the pulse is generally below 120. Twenty-four hours afterwards, the tonsils present a deeply congested condition, and are often so enlarged that they meet in the centre. The uvula is generally oedematous and congested. In the earliest stage of the disease, the exudation from the crypts mar be so great as to form one large ))yramidal patch between the two pillars of the fauces. This patch is of a whitish colour, but ])Osse.sses less tenacity than that of di[)litheria, and has no inflammatory zone ; and upon its removal, the orifices of the crypt will be found plugged with exudation, showing the typical appearance of follicular tonsillitis. The child may or may not complain of a sore throat, generally not ; bi;t this is generally due to the soft character of the food. The patient, if old enough, comjjlains of headache, pains in the limbs and back. There is pain on pressure over the tonsils; these can be felt enlarged under the angle of the jaw, Ijut there is no marked enlargement of the lymphatic glands, as in diplitheria. The skin is dry, the face flushed, and there is albuminuria in many of the cases. Within forty-eight hours, these symptoms gradually subside, if the case is going to 1)e a favourable One. 2s 2 996 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. If the patient is not exposed to any fresh infection, by being allowed out of doors, con\alescence generally results by the fourth or fifth day. These symptoms have been almost invariably the same in the 315 cases that I have observed, but some of them have been a cause of great anxiety to me, owing to the supervention of other diseases due to other septic causes, the chief one being that of diplitheria. In every case where this has occurred, I have always traced it to the patient being allowed out within the range of some particularly offensive gutters. Amongst others, I would mention two cases in particular : — A child of 10 years of age, who had had one or two attacks of follicular tonsillitis, for which she had been under my care during the prevalence of an epidemic of this disease, became exposed to septic influence, and was laid up for two or three days suffering from the same. There were none of the symptoms of diphtheria ; the case progressed well, and all the exudations disappeared ; but before the tonsils resumed their normal condition, she was permitted to go out in the evening. Within a few hours a relapse occurred, but not being ill enough, as the parents thought, to send for me, she was brought to my surgery. 1 found well marked diphtheritic patches on her tonsils. Twenty-four hours after, the disease had attacked the larynx, and in spite of tracheotomy being performed, she died. Just three doors from where this pjatient lived, 1 have been repieatedly called to a household, where every child is liable to attacks of follicular tonsillitis. The symptoms have all l>een the same as those described, and T never had any cause of anxiety with any of the cases ; but after the death of this child, the cases there appeared to get more and more obstinate (the gutters all the while becoming more objectionable), until at last, three months after the death of this neighbour's child, one of the patients in the house had an attack ushered in with violent convulsions ; patches appeared on the throat of a more tenacious character than usual, and finally, the symptoms became distinctly di[)htheritic. Two months after this, another child in the same house was affected with diphtheria ; l>oth these cases recovered. I may mention at the time, in connection with this, that I removed the tonsils of a child in this last house, and she was foolishly permitted to go to Sunday School the same afternoon. The malignant character of our drainage system in Williamstown may be guessed, when I state that this short walk, where she was exposed to the exhalations arising from the gutters, resulted in the raw surface of the tonsils being covered with a copious exudation within thirty-six hours, with all the symptoms of follicular tonsillitis. There is a fatal case of diphtheria quoted in the Lancet, where tracheotomy was performed. On post-mortem examination, ulceration of Peyer's patches was found. The case had an unusually high temperature. A similar case, where a youth aged 14 was attacked by follicular tonsillitis, and where the patches disappeared within fortj^-eight hours, his tem})erature gradually becoming normal, against my directions took a walk before convalescence was established. On the next day, his ienii)erature was 105'. In a day or two, the case assumed a typhoid character, and on the eighteenth day, he died from i)erforation of the bowels, having suffered for three days previous to his death from uncontrollable luemorrliacre from the bowels. I CORRELATION OF FOLLICULAR TONSILLITIS IN CHILDREN. 997 Witli respect to the association of follicular tonsillitis Mith scarlatina, I may mention that in no cases have 1 seen an}- i)eeling of the skin after an ordinary attack of th<> former, but I have seen tlie two diseases attack dift'erent persons in the same household : — A young man, who had suffered from repeated attacks of follicular tonsillitis, was once more laid up with an attack of tliis disease. He recovered without any other symptoms, and there was no peeling of the skin. His illness last<;d four days. His sister, married, was also attacked, but in a mild form. Her two childi-en, aged 8 and G years respectively, two days after the first case was attacked, showed symptoms of scarlet fever, which after a long and sevei'e illness, terminated in peeling, and in one case in nephritis. This child recovered. These cases I have mentioned, in order to show the association of follicidar tonsillitis with other diseases of septic origin. The frequency with which I have observed a series of cases, where there has been no intercourse between the families attacked, led me to believe that there must be some other cause for this illness than an ordinary chill, and I believe that that cause is no other than the defective system of drainage that prevails in Williamstown. I believe that follicular tonsillitis is common elsewhere ; but the flat nature of the ground on which the town is built, and the consequent stagnation of the sewage in the open drains, seem to me to account for the lai-ge nund^ei- of cases prevailing in this town. I need not give a detailed account of our sanitary defects, because they prevail alike in Melbourne and the other suburbs, but I should like to point out what the condition of things must be in a town, where the majority of the liquid manure finds its way into the open gutters ; where the water supply is cut oti" for half the year for the whole of the working day ; where twice a week the green deconqwsing material fermenting in the gutter is removed by the town scavenger, and jjlaced in the centre of the road, to be dried up by the first hot wind, and distributed in generous projiortions to the unfortunate inhabitants of our town. When added to these conditions, in the older ])arts of the town, we have numerous sweltering lagoons of filth, caused by the building of houses on land sold by syndicates during the late boom, without the slightest attention being paid to the disposal of the drainage from the houses, is it any wonder I ask, that sore throats prevail of such malignant nature. In several districts of Williamstown, this disease has assumed quite an epidemic character, and T have noticed this more particularly after a shower or two, when the ground has connnenced to dry : but during the last hot weather, eases have been almost as numerous. In two districts of the town, when the gutters liave been unusually foul, nearly every house had a case of follicular tonsillitis, and in some cases there were two or thi'ee in one house, ^lore particularly I would mention one street leading do\ni to the bay, Avhere there is a row of houses having most offensive drains both at the back of the houses and at the front. In one house, five cases of this disease occurred — the fiist being a child of 3 or 4 years of age, liis two sisters then became afiected, and finally the parents of the children. At the back of their house I liad another case, wliich followed the usual course. Their cousins who lived in the same house and who had been away for a change, on returning, were all laid uj) with the same 908 IXTEKCOLONIAL MEDICAL COXCiRESS OF AUSTHALASIA. complaint. All these cases recovered very quickly. In another house, I have seen every child in the house attacked most severely with follicular tonsillitis. In the same house, there are now four severe cases of typhoid fever, three of them having also sutiered from follicular tonsillitis. In another house in the same locality, where a female was laid up, she was visited by a young girl who lived at some little distance where there were no cases at the time ; within a day or two, she also had an attack, but much milder in character. I could go on for some- time giving instances of its infectious character. The treatment I adopt in these cases, has always been to reduce the temperature as speedily as possible, in order to avoid complications, such as pneumonia. Arc— not an unnecessary ]>recaution I have found, when I have neglected to do so. I have found that I could in most cases accomplish this by means of salicylate of soda, together with an ordinary saline niixture ; but lately I have found that in Phenacetin-Bayer, one of the latest synthetical compounds introduced in antipyretics, I had a most reliable remedy for this j^urpose. In a few hours pain is relieved,, and the temperature becomes nearly normal. Indeed, in all cases in children, as well as in adults, where a high temperature prevails, I have lieen astonished at its antipyretic virtue and its sedative effect, and I now invariably use it in ])reference to anti[)yrin or antifebrin, as I find it is less dejiressing, and there is not the same tedious convalescence after its prolonged use, as there is after the former named drugs. I feel that this ])aper is deficient in many things that should make it complete ; for instance, the microscopical character of the exudation, and a complete series of tempeiatures, itc, but the little leisure permitted Ijy a general ]}i-actice has not allowed me to render it more complete. My object in writing is to draAv attention to a simple disease very evident to the eyes, which I believe is solely due to our bad gutters and system of drainage, and to endeavour to draw some analogy between the causes of this disease and of typhoid fever and diphtheria, with a view of showing the means of preventins; epidemics of such diseases by a comj)lete and scientific system of drainage. PATHOLOGICAL MUSEUM. CATALCXiUI-: OF SPECIMENS Submitted hy 11. 15. Allen, M.D. Professor of Anatomy and Patholojjy in the University of Melbourne. 1. Ai'terio- venous poi)lite;il aneurism, following a strain of the knee which fractured the patella. (See Australian Medical Journal, Septendjer 187t^.) 1'. Aneurism of sinus of ^'alsalva of aorta, almost tilled witli laminated clot. 3. Aneurism of aortic arch oi^ening into the pulmonary artery, and subsequently bursting into tlie trachea. 4. Dissecting aneurism of thoracic aorta, starting in a patch of atheroma in the third part of the arch, and extending upwards to the pericardial reflexion, and downwards to the diapliragm. •>. Pyriform aneurism, arising from the junction of the ascending and transverse portions of the aortic arch, comj^letely occluded l)y laminated fibrin by unassisted natural processes, (i. Huge aneurism of aortic arch, rising into the neck in front of the I'ight carotid sheath, distorting the origin of the innominate artery, and simulating innominate aneurism. 7. Aneurism of upper aspect of transverse portion of aortic arch, with enormous deposit of pale clot, occluding the orifices of the great arteries. Consciousness was retained twenty-four hours before death. 8. Pulmonary stenosis, w itii patent foramen ovale. Tlie segments of the pulmonary ^■alve are fused together. The orifice is reduced to a small chink. The foi'amen o\ale is patent, almost circular, an inch in diameter. The patient, a married woman aged 29, died greatly emaciated, with pulmonary tuber- culosis and bronchi-ectatic cavities. There was no dropsy. 9. jMalfoi-mation of pulmonary valves. The valve consists of a single annular segment, tliick and opaque, Avith narrow orifice and beaded edge. There is one sinus of Valsalva, anteriorly and to the right. The valve is bound down to tlie arterial wall ])Osteriorly. The })ulmonary artery is very narrow. The light ventricle hypertrophied, but not notably dilated. The ])atient was more or less cyanotic from birth. She died at the age of 27, with e.xtensive caseous pei-i-bronchitis. There was no dropsy. A loud bruit was heard o^er the sternum, especially opposite the second interchondral space. 10. Aorta and pulmonary artery combined, arising by one trunk from two ventricles. 11 and 12. Tricuspid vegetations. No other \alves affected. Two specimens. 1000 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. 13. Recent mitral and aortic endocarditis from a case o£ typhoid fever. 14. Aneurism of trmik of pulmonary artery. 15. Sudden extensive rupture of inner coats of a tiabby friable aorta, apart from advanced atheroma. 16. Embolisms of cerebral arteries with consecutive arteritis and aneurisms. 17. Cirrhosis of lung. 18. Fibro-pigmentary consolidation of lung with basal cavity, from a miner aged 55. 19. Acute typhlitis, the walls of the ca-cum being greatly swollen, soft, pale, but not yet absolutely sloughing. 20. Acute dysentery, with sloughing false )nembranes. 21. Colitis and proctitis, with large pale oval ulcers having thin under- mined edges. "22. Clironic dysentery, with thickening of the muscular coat, and irregular ulceration and granularity of the mucous membrane. 23. Chronic dysentery, with atrophy of the coats of the intestine, and ragged paie ulcers of the mucous membrane. '2i. Chronic dysentery, with papillose ulceration of the mucous membrane. 25. Syphilitic rectum from a woman. Immense thickening of the coats; extensive cicatricial stricture just above anus; irregular pitting of the intestine above the stricture ; and chronic serpiginous ulceration for several inches higher up. 2(5 and 27. Two cases of multiple intussusception of the small intestine obtained from children who died respectively of diphtheria and of obstinate vomiting after lithotomy. In both, intus- susception occurred in the death process. In one case there were ten, in the other eleven, distinct intussusceptions. In ■ the great majority of instances, the invagination was down- wards, but in some it was upwards ; and occasionally a down- ward and an upward invagination occurred in close proximity, so that the two incarcerated parts came almost into immediate relation. 28 and 29. Two specimens illustrating fatal intussusception ; one is a case of slow intussusception at the ilio-cjecal valve ; the other is a case of rapid intussusception in the ileum, the invaginated portion being thickened by inflammation and hjemorrhage, and rapidly sloughing. 30. Cystic kidneys, weighing together 68 ounces. The patient died of tubercular epididymis and general tuberculosis consequent upon it. 31. Renal calculi (Anstraliau Medical Journal, November 1883). 32. Tubercular ulcers in ureters. 33. Tubercular epididymis. 34-38. Series of complicated hydroceles — (a) Encysted hydrocele in the usual position, with an opening below into the tunica vaginalis. (b) Hydrocele of the tunica vaginalis, covering the front of the testis, and overlapping in its upper part an encysted hydrocele — (two specimens). (c) Encysted hydrocele, with ha-matocele of the spermatic cord I PATHOLOGICAL MUSEUM — CATALOGUE OF SPECIMENS. 1001 (c/) Hydrocele of tunica \iiyiiuilis of a partly descended testis. The testis had remained a short distance below the external abdonunal rin) from the same patient, (ri) Enlarged, somewiiat uneven on the surface, densely fibre id, of .stony hardness^ PATHOLOfilCAI. MUSEUM — CA'lAr.OfilK OK SPECIMENS. 1003 the testis and epiditlyinis fused together, but no gummata present ; (b) still larger, also hard, I)ut less so than («), smooth on the surface, and containing distinct opaque dry yellow guuiniata, end)ed(led in fibroid tissue. (c) showing small gummata lying in dense fibroid tissue. The surface is irregular and knobbed, with severe ciironic inHanunation of the tunica vaginalis. 89-90. Syphilitic lesions of liver - (n) huge gununata, dry and tirm. (h) irregular cicatrices. 91. (Syphiloma of tongue, superficially sinuUating ei)itiielioma, Ijut deeply presenting a sharply defined oval infiltration, only partly masking the normal structure. 92. Syphilomata of frontal lobe of brain, with central softening. 93. Syphilomata of dura mater, showing diffuse fleshy thickening, with low lobulated growths on the cerebral surface. 94. Syphilomata of \w,i mater, forming ;dong the arteries at the base of the brain [Aiistrrdian Medical J oirnial^ April 1S82). 95. Firm flljromata in both ovaries. 96. vSoft pedunculated fibroma of labium majus. with superficial excoriation. 97. Huge uterine myoma, \\'\W\ a moderate degree of cystic de- genei-ation. One quarter of the tumour is shown as a wet specimen ; one half of the tumour is shown dried, being shrivelled to extremely small dimensions and extremely heavy. Query — Are the modifications of the size of uterine fibroids under treatment, or in i-elation to the catamenia, dependent on the varying amount of fluid inflltrating their substance ? 98. Pedunculated myoma hanging from the cer\ ix uteri, and filling the upper part of the vagina. 99. Fasciculated myoma of alxlominal wall. This tumour grew in the skin of the abdomen of a Chinaman, and, having attained a diameter of nearly four inches, is enucleating itself. The skin is adhei'ent, thinned, and fit parts perfoi-ated, the firm rounded dry lowly lobulated growth being completely exposed in the perforated parts. As Sir J. Paget says, such enuclea- tion is a natural tendency of myomata, and not dependent on the contraction of the muscular tissue in which they arise. {Auiftrailan Medical Journal, October 1S80). 100. Compound cauliflower condyloma of labium m.ijus. 101. Sarcoma of left testis spreading up the spermatic veins, infiltrat- ing the left kidney, extending along the left renal vein into the vena cava, and presenting into the right auricle. Fun- gating sarcomata of lungs and sarcomata of li\ er. 102. Primary sarcoma of lung, forming a huge homogeneous fii'm grey growth, comi>osed of small spindle cells. 103. Lympho-sarcoma of mediastinum o\('rlapping the heart {A ustraltan Medical Journal, Octol)er 1880). 104. Melanotic sarcoma of lungs, liver, heart, breast, lympliatic glands along the pancreas, itc. {Australian Medical Jovnad, No- vendjer 1880.) 1004 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. 105. Sarcoma of peiiostevim of bodies of dorsal ^•ertebra% spreading through the intervertebral foramina, and extending along the dura mater. 106. Sarcoma of kidney of a child, containing striped muscular fibres. (Australiaii Jledical Journal, ]March and April 1886.) 107. Central sarcoma of both humeri, jvist below the surgical necks. 108. Discoid carcinomata of the mesentery along the line of intestinal attachment, spreading into the intestinal wall. Carcinoma of the semilunar ganglion. (Australian Med icalJotiruaI,^lay 1883.) 109. Simple cyst of liver, five inches in diameter, containing simple serum. (AHstralian J/edical Journal, May 1883.) 110. Small cystic growths from lining membrane of both ureters. 111. Congenital sacral cyst of large size, formed by a terminal spina bifida. 112. Multilocular ovarian cyst, Avith papillomatous growths from the external surface. 113. Multilocular ovarian cyst, with much solid growth at the base. These growths consist of laminated de2D0sits of epithelium and cholestearin, encapsuled in fibrous tissue, and vary in size up to more than an inch in diameter. (Australian Medical Journal, July 1880.) 114. Dermoid ovarian cyst, with gTowth of bone, teeth, and hair. (Australian Medical Journal., August 1882.) 115. Dermoid ovarian cyst, with large growth of hair, and with large steatomatous deposit. 116. Cholesteatoma growing from peritoneum at the fundus uteri. (Australian Medical Journal, November 1879.) 117. Cystic kidneys, weighing sixty-nine and forty-one ounces, fi'om a man aged 43, who died of ura-mia. 118. Seven-flukes (distoma hepaticum) removed from the bile ducts of a man. There was a large foul abscess of the liver, and dilatation and suppuration of the bile ducts within the liver. yote. — In two other cases, Professor Allen has found a single fluke in the bile ducts of human beings. Specimens of Hydatid Disease. 1. Hydatid of liver, showing a thin shining perfectly organised adventitia, resembling a flbro-serous membrane. 2. Hydatids embedded in right lobe of liver, with perfectly organised adventitia. A second cyst growing from the lobulus Spigelii is thin-walled and movable, and is inserting itself between the layers of the small omentum. •3. Hydatids of liver, several specimens, with thick opaque irregular adventitia, imperfectly oi'ganised. Query — Does the charac- ter of the adAentitia depend on the rate of development, or on the situation in which the growth starts- — a thin, smooth- walled sac being formed when the embryo lodges within a portal capillary, and a less highly organised sac being produced when the embryo developes among the hepatic cells? 4. Hydatid of the liver adherent to the diaphragm, and having a very tough secondary adventitia, nearly an incli tliick, developed between it and the diapliragm. PATHOr-OGICAL MUSEUM— CATALOOUE OF SPECIMEX.S. 1005 n. Multiple liydatids of li\er. One large cyst in the right lobe was suppurating. Others were stufted full of collapsed cysts and concreted biliary matter. Others were mature, containin<>- limpid tiuid. The patient died of dislocation of the spine, caused by a fall. Xote. — A very narrow septum may di\'ide a suppurating hydatid from one showing no signs of degeneration or inflammation. 6. Multiple hydatids of liver. One very large thin-walled cyst has developed at the extreme right of the liver, and is l)ounded in the greater part of its extent only by the thickened serous coat. Another grew from the back of the left lobe, and bulges into the fissure of the vena cava. A third, lying a little further forward on the under surface of the left lobe, is separated fi-om the foregoing only by the thin fused adven- titial. A fourth is buried in the left lobe, at its ujsper aspect. A fifth is embedded in the left lobe, and abuts on the serous capsule at its anterior border. A sixth is thoroughly predun- culated, and is attached to the anterior border of the left lobe, just where the serous coat forms part of the ad\entitia of the tifth. The first cyst was much the largest, and evidently at one time was embedded in the right lobe, abutting on the serous coat only to a limited extent. But its subsequent increase in size caused it to be bounded by the serous coat over the greater part of its surface. There is a limited patch of thickening in the part of the adventitia nf>w formed by the serous coat, sharply defined and circular, indicating the original connection of the cyst with the serous capsule. 7. A hydatid of the liver five inches \n diameter, with thin well- organised adventitia, but containing, instead; of a single mother-cyst and its progeny, a mass of small cysts loosely adherent together in an oval mass, y. Part of the adventitia of an old-standing hydatid, with flakes of gelatinous membrane adherent to it. Tiie adventitia is- uneven, and altered by inflammation into an imperfect granu- lation tissue, partly organised. Note. — Such true adhesion of the mother-cyst to the adventitia is very rare, and is seen only in old-standing cysts. The adhesion is an abnormal occurrence in the life of the hydatid, and probably never occurs apart from degeneration and inflammation. 9. Hydatid of the liver opening into the hepatic duct. 10. Hydatid of the liver perforating the diaphragin, and forming a cavity in the base of the lung, bounded by indurated lung- substance, and opening into a bronchial tube. 11. Hydatid of the liver, treated by tapping and insertion of a drain- age tube between the rilis. This specimen shows how the contraction of the cyst interferes with drainage so conducted. 12. A series of specimens of old-standing hydatids of the liver, showing changes in the adventitia, partly thickening, contraction and puckering, partly calcification. In some, the earthy matter is uniformly diffused, foi-ming a complete calcareous shell ; in others, it is deposited in irregular nodules. 1006 IXTERCOLOXIAL MEDICAL COXGRESS OF AUSTRALASIA. 13. A series of specimens, sIiowin<^ retrogressive changes in the contents of hydatid sacs : — Collapse of the cysts, accumulation of fatty smegma, deposit of biliary matter, which in some cases forms large concretions. 14-. Primary carcinoma in the thick adventitia of a retrogressing hydatid of the liver. 15. Secondary carcinoma in the ad\entitia of a hydatid of the liver. The primary scii-rhus grew in the pancreas. The adventitia of the hydatid was formed in part by the thickened serous capsule ; and in this part of the adventitia, plates of scirrhous carcinoma huve developed. JVote. — Professor Allen has seen a case of primary carcinoma of the liver, forming a huge mass in the left lobe, with smaller tumoui's scattered tlii'ough the liver ; a hydatid as large as the mature fcetal head lay in the centre of the liver, and was not involved in the cancerous growth. In another case there was a carcinomatous growth, 3i inches in diameter in the liver, abutting on the anterior border ; while two large hydatids were present in the posterior part of the liver, one of them l)eing separated from the cancer by only half an inch of liver tissue. 16. Small liydatid in the muscular wall of the left ventricle, bulging under the pericardium. 17. Hydatid of spleen of huge size, forming an ovoid sac, with tough thin adventitia, representing little more than the thickened capsule. The inner surface of the adventitia is opaque, yellow, and uneven. 18. Hydatid of the s[)leen, with ^■ery irregular adventitia, formed partly by altered splenic substance projecting in great lumps into the cavity, and partly of the indurated greatly thickened capsule. 19. Huge hydatid of spleen, showing the mature mother-cyst, and the comparatively smooth adventitia, wliicli is formed chiefly from the serous coat. iVo^e. — Other hydatids of the spleen are on the shelves, but in none is there that perfect organisation of the adventitia which is seen in many liver hydatids. Cysts of the spleen do not readily collapse after tapping, and special cai'e is necessary in their drainage. In one case, however, in a man who was brought to the Melbourne Hospital in a dying state, the autopsy revealed several small hydatids in the spleen, with calcified adventitiie, easily shelled out of the tissues around. 20. ^Multiple hydatids of the omentum. 21. Hydatid of the omentum, bounded by tirm adventitia, and contain- ing collapsed degenerating cysts closely crowded together. 22. Hydatid, with very thick adventitia, attached to the omentum. Removed by Mr. FitzGerald by abdominal section. ]\/'oie. — These movable omental hydatids are eminently adapted for removal by abdominal section. Tapping seems to be attended with special danger. 23. — Hydatid of pelvis. A cyst about four inches in diameter, con- taining clear fluid and scolices, which was found lying- destitute of adventitia in the vesico-uterine pouch. It was adherent to the pex^itoneum only by a small tag of gelatinous membrane {Auiitrallan Medical Journal, April 1882). I PATHOLOGICAL MUSEUM CATALOGUK OF SPKCIMENS. 1007 24. Spherical liydatid, 4] inolie.s in diameter, attached to fundus ot uterus and hhidder, and opening into the right Fallopian tube, which is dilated and full of cysts (Anstndian Medical Journal, October 1879). 25. Hydatid in the substance of the diaphragm. One large and several small gelatinous cysts are packed together within one adventitious sac. '2Q. Mature hyd;itid of kidney, about four inches in diameter, projecting boldly under the capsule. Note.—V>v. C. Smith, of Casterton, exhibited hydatid cysts of the kidney, which passed down the ureter and escaped by the urethra. 27. Multiple hydatids of livei', with complicated masses of hydatid cysts growing in the pelvis, adherent to all the structui'es around. 28. Hydatid of the right ovary, of large size. Xote. — This is the only case of ovarian echinococcus wliich has come under Professor Allen's observation. Specimens 2(5, 1*7, and 28 were obtained from the same case. 29. Hydatid encapsuled among coils of intestine, and opening into the jejunum. The patient had obscure Habby swelling of the abdomen, with chronic dyspeptic symptoms. The oriiice between the cyst and the bowel was well defined, and of long stjinding. Tlie sac contained a foul mixture of bilious intestinal matters, and decaying gelatinous membranes. 30. Hydatid growing from under surface of the anterior part of the liver, in the midline of the body, which closely resembled aneurism of the cteliac axis. The bruit, pulsation, and thrill were strongly marked; but the lateral pulsation was not distinct, and the aneurismal signs were greatly diminished in the knee-elljow position. 31. Retrogressing hydatid between the liver and diapln-agm. Xote. — Several other instances of hydatid in this situation are recorded in tlie pathological registers of the Melbourne Hospital. 32. Hydatid of limited size, with firm adventitia growing from the front of the sacrum, extending through the anterior sacral foramina, and up the spinal canal as far as the last lumbar vertebra. The liydatid within the spinal canal was bounded only by the mother-cyst. It contained great numbers of daughter-cysts. There was partial paraplegia. Finally, the cyst ruptured into the subdural space, and there was rapid ascending paralysis. (See Australiaii Medical JournoA, ^lay 1879.) 33. Calvarium from a girl who had intracranial hydatid. Tlie skull cap is expanded, greatly thinned, with immerous perforations, closed only by membrane. 34. Hydatid cyst growing from the superior surface of the right orbital plate of the frontal bone. 35. Large hydatid in the left frontal lolje of the cerebrum, presenting at the orbital surface. Specimens 34 and 35 were removed from a girl aged 13, who died after six months' illness. At first, she suffered only from epileptic fits; but two montlis before death, she lost power in the left leg, and gradually became unable to stand; then unable to turn herself in bed. Finally, she became unconscious, and died in convulsions. 1008 IXTKRCOLOXIAL iMEDICAL CONGRESS OF AUSTRALASIA. 36. Hydatid of cerebrum in the right mid-convexity, occupying the marginal convolution and the lower part of the ascending painetal. Bulging sliglitly beneath the arachnoid, and abutting deeply on the body of the lateral ventricle. There is only a very slight induration of the brain tissue around. (See Cobbokfon "Parasites," 1879, pp. 140-141.) 37. Huge hydatid following out of the upper pai't of the left cerebral hemisphere, from the front of the occipital lobe forward into the back of the frontal lobe. 38. Hydatid cyst in left occipital lobe of cerebrum, presenting at the extreme posterior end of the hemisphere. Notes of Cases of Hydatids from the Pathological Records of THE ^Melbourne Hospital, added by Professor Allen. 1. A case of hydatid behind the peritoneum and in front of the right psoas muscle, extending from the diaphragm under Poupart's ligament into the thigh. The patient died of aneurism of the aortic arch. 2. Large hydatid growing in and distending the gall-bladder. The liver was cirrhosed. There was jaundice, with epistaxis and intestinal lijemorrhage. 3. Huge cyst of right lobe of liver opening into the ascending colon. 4. Right lobe of liver completely occupied by a cyst which opened freely into the cystic duct. There was slight jaundice. 5. Large cyst in centre of liver. A hepatic duct admitting a large catheter opened into it. General jaundice. Contents of cyst deeply bile-stained, but not purulent. 6. Two large hydatids in the same liver, sepai'ated only by the fused adventiti;>? — one suppurating, the other infiltrated with bile, but not suppui-ating. 7. Cyst between liver and spleen passing through the spleen to become adherent to the diaphragm. 8. Right lobe of liver completely occupied by a cyst. A branch of the hepatic artery close to the transverse fissure opened into the cyst, which was tilled with partly decolorised clot. Death was due to primary tuberculosis of the trachea with secondary acute pulmonary tuberculosis. 9. Cyst occvipying the lower half of the abdominal cavity ; bounded in front by the abdominal wall, and elsewhere by coherent coils of slate-coloured intestine and mesentery. Full of clear limpid fluid. No daughter-cysts. In the left iliac region, there was a thick layer of honey-combed lymph, outside the mother-cyst, adherent to the adventitia. Tliis cyst occurred in the same patient as the foregoing. Notes of eigliteen cases of hydatid disease within the chest, reported by Professor Allen, will be found in the Aiistralian Medical Journal for March and May 1881. The .specimens from several of these cases were shown at the Congress. APPENDIX. ANTISEPTIC SURGERY AND SOME OF ITS RESULTS. By R. 13. DuxcAX, F.R.C.S. Ed. (Exam.) Fellow of the Faculty of Surgeons, Glasgow. Hon. Surgeon to the Kyuetou Hospital. Antiseptic surgery, though occupying a somewhat difterent field to aseptic surgery, has ahnost identical aims. By the one method we preserve a wound perfectly pure ; by the other we render it so, when, as in an accidental wound, it has been previously contaminated. To those who, like myself, have watched its progress, and endeavoured to carry its principles into every day practice, it is a matter fraught with very great issues, and deserving of the most serious consideration. Like many great discoveries in our profession, it has been subjected to an immense amount of criticism, and an unlimited amount of abuse. It has had innumerable imitators, who, in many extraordinary ways, have tried to establish systems of their own, and who in many instances would have us believe that antiseptic surgery is possible with "anti- septics left out." Hence the phrase, that every careful surgeon is an antiseptic surgeon, whatever means he may employ. Listerism presents, to those who believe in it, a creed of no ordinary kind. There is no room in it for any vacillation, hesitancy, and doubt. It compels obedience to a certain line of action, from which there can be no deviation. Details may vary, but the principles remain fixed and immutable. Mr. Savory, in his celebrated address "On the Prevention of Blood-poisoning in Surgical Practice," * says, speaking of Listerism, " But the principle on which it rests is a sound one, the logical outcome of established facts." What those principles are, their application to wound treatment will show. What they should enable us to accom- plish, may be inferred from the following statement by a recent authority on the subject. He states : — " It cannot now be denied that the surgeon's acts determine the fate of a fresh wound, and that its infection and suppuration are due to his technical faults of omission and commission." This is undoubtedly true ; and it is a matter for sincere congratulation that, thanks to Listerism, we have reached something like exactness in surgical therapeutics. And is it not a matter of daily experience, that just in proportion as our antiseptic plans are carefully and judiciously carried out, so will our results be favourable or other- wise? The marvellous and rapid strides which operative surgery has made within the last few years, have been largely due to the safety which antiseptic measures confer. Operations are now undertaken with comparative unconcern, which were formerly a dread to the suigeon, and always a peril to the patient. Regions have been invaded which were thought to be sacred from the surgeon's knife, and wounds of the limbs are now recovered from, which * Medical Timft and Gazette, August 1879. 2t 1010 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. in pre-antiseptic days would have imperatively demanded amjiutation. Hospitals, which before were almost untenable, hot-beds of blood- poisoning, and on the point of being pulled down, have not only been rendered habitable by antiseptic means, but some of the most brilliant successes on record achieved within their walls. It has passed far beyond the limits of general surgery, and not to particularise other fields, in obstetric practice, most brilliant and lasting results hav^e been attained. In this direction alone, had it had no other raison d'etre, the immunity from disease, and the saving of life, which it is daily effecting, would entitle it to the gratitude of mankind, and give it an imperishable fame. The " germ theory," on which Listerism is based, has had considerable influence in retarding its acceptance by many who are otherwise inclined to view it favourably. This is not to be wondered at, when we hear surgeons of eminence speak of so-called germs, and sneer at their power of doing any harm whatever. Fortunately, however, bacteriology is now so firmly established, and its conclusions so clearly worked out, that no one can deny on scientific, or any other grounds, the important part that they play in diseased processes most intimately connected with surgery. It now supplies the proofs in abundance, which were in a measure defective in the early investigations of Schwann, Pa«teur, and Lister. On what a solid foundation the relation of micro- organisms to sui-gery i-ests, will be a]){)arent when we consider the means which have been adopted to prove the connection. " No micro- organism is regarded as the cause of a disease, unless it is, in the first place, found to be constantly present in that disease, either in the blood or in the tissues ; secondly — unless, when carefully isolated and culti- vated, it can, when introduced into the body of a healthy animal, give rise to the original disease, and be again found in quantity in the body." * If we bear in mind that even the " oil of turpentine injected under the skin will not produce suppuration without the presence of a germ ; and if some cultivated pus-producing micrococcus be rubbed on the intact and healthy skin, it will occasion inflammation and a wide-spread crop of boils," t the bearing of germ life on surgical processes is further exemplified. Wound infection, and the various forms of blood-j)oisoning which in many cases follow, are undoubtedly due to si)ecific micro- organisms. Whence do they come ? Omitting for the present the more obvious sources, such as the surgeon's hands, instruments, sponges, and the various ai)[)liauces of an oj^eration, the question may be asked — How far is the air res[)onsible for them 1 To those who use the spray, this is a matter of much importance. Let us see what the air is capable of 4oing ; and first of all, I deny that there is surgically pure air, any more than there is surgically pure water. The micro-organisms of the air are capable of setting up decomposition in every fluid and solid that possesses the elements of decomjiosition. " tSome require an animal diet, others a vegetable one, and for some a specially ]jrepared soil is necessary. They may be cultivated through successive generations, and in different media, but they will retain their characteristics in every case." % * Power, "Bacteriology in Belation to Surgery," Bradshaw Lecture, British Medical Journal, December 1886. t Ibid. \ Coats' " Manual of Pathology. " AXTISEPTIC SDRGERY A\I> SUM K OF 1 rs IJKSULTS. 1011 The results oLtaineJ, in meat infusions and nuiuorous other ways, are so constant and unvavying, that their aiiplication in regard to the all- imjiortant question of wound treatment ought at once to meet with universal recognition. No sooner liad bacteriology 'u-ought to liglit these facts, apparently so important in tlu? ])i'actioe of surgery, than means were taken to give them an entirely difterent complexion, and an endeavour made to nullify their practical application. In this attemj)t, the chemico-biological process of the putrefaction of meat infusions is not questioned, but its relationship to wound treatment is altogether denied, as will be seen from the following statement of the case by a high authority : — " Animal fluids exposed in open vessels to the air after some time become putrid, the length of time varying v^ith the state of the air ; and so it is forth- with concluded, and argued l)y many, that if fluid upon the surface of a wound be exposed to the air, it must, while there, become jmtrid also. But the fact is, any one who cares to witness it may see fluid at any time on the surface of exposed wounds, which is not putrid. And the explanation of this most familiar fact is simple enough, that the fluid in the vessel has been kept until it has become foul, while the fluid on the surface of a wound in process of repair, which is daily watched, ajid properly managed, is ever being i-enewed. The same fluid ought not to be allowed to remain long enough to midergo a mischievous change." — Savory. The feebleness of this reasoning, although it emanates from a high authority', opposed to Listerism, will be appai'ent at a glance. The whole argument turns on this — ^We are not to allow fluid to remain long enough on a wound to undergo putrefactive changes. We see fluid on the surface of wounds that is not putrid. Granted ; but in how many wounds deliberately made are we able to watch the surface and remove the constantly renewed fluid 1 Practically none. Take an amputation wound for instance. Is not the whole wound surface shut out from our view the moment the last stitch isinsertedl and is not the deconq)osition or putrefaction of Ijlood and serous fluid, which may afterwards follow, merely a question of whether the wound is aseptic or not ? There is no reaching it to remove so-called constantly renewed fluid. If we did, the proceeding would only be meddlesome and bad surgery. Even in many surface wounds of large extent, and where there has been much laceration, it may be, and generally is, impossible to keep them sweet without antiseptics. The great conservatism of operative surgery, aided by antiseptic means, is well illustrated when applied to the fingers. A finger, say, is crushed to the extreme limit that surgery will allow without resort to amputation. What eftbrts will we make to save it? Although apparently a simjile matter, it is in reality a crucial test between two methods. If rendered aseptic, and " kept in pickle"* by constant mercurial dressings, success will almost be assured in every instance. If treated wholly without antiseptics, the results will be disastrous in a least two-thirds of the cases treated. And why? In one method we keep the damaged tissues free from micro-organisms, and consequently from decomposition, and allow them to regain their impaired vitality ; in the other, we do exactly the opposite. " Cameron, GUugvw Medical JouiikiI. 2t 2 1012 IXTEKCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. In the minor surgery of country practice, I liave liad frequent opportunities of verifying this, especially in very hot weathei-, when the difference is very conspicuous. By keeping the parts in continuous contact with suhliniate solution, every vestige of tissue will be saved that it is possible to save. Adopt any other ]»lan, even with the aid of antiseptics, other than this particular one, and the result ^\ill be extremely problematical. It is believed that irrigation of a wound after an operation with antiseptic solutions is sufficient to destroy any germs that may have lodged in it. But does it do so ? If any doubt remains, why not jjrevent them in the first instance, as the spray is callable of doing 1 Is there any other parallel in our sui-gical procedures where we allow an admittedly dangerous condition to be established, with the dubious belief that we may or may not be able to neutralise it 1 AYound infection, by micro-organisms from the air, is undoubted, and why not take means to prevent it. " The myriads of particles of filth or dust filling the air in all inhabited localities, contain, according to indubitable evidence, a very large proportion of spores or seeds, that on falling on the wound promptly develop, and set up feruientative processes known as decomposition." * Take again the case of a fracture where the injuries are entirely subcutaneous, while the splintering of lione and laceration of the soft parts may be great and widespread. What is the consequence 1 Perfect recovery in practically every case. Allow germ-laden air to gain admittance — which it does when the fracture is compound — and what is the difference ? On the one hand perfect recovery, as already stated; and on the other, in numei'ous cases (I am afraid to say how many), some of the following evils, most of them of grave import, and some of them absolutely fatal :^" Traumatic fever, inflammation, sup- puration, waxy degeneration, hectic fever, formation of abscesses, slough- ing, acute necrosis, gangrene, erysipelas, sejitic intoxication, septi- caemia, and pyaemia. "t And is not the whole ftibric of subcutaneous surger}" based on these considerations — air, or no air 1 The only effectual remedy against air contamination, at least in purely aseptic surgery, is the spray, or failing that, the thorough use of an irrigator. Unfortu- nately, the spray has been almost abandoned ; and this is perhaps the most important modification that antiseptic surgery has undergone in recent times. Whether it is a wise one or not, remains to be seen. On what grounds this has been done, I have never been able clearly to comprehend. I am open to recognise the reason of its absence in abdominal surgery. But in operations in hospital practice, where it can be efficiently carried out, it is a positive gain. I have on many occasions in cases of amputation (and excision of the breast especially), never touched the dressings from the moment they were first put on till the wound was perfectly healed. The successes attained by this method, and the dressing of which it forms an essential part, have been simply marvellous, and have been equalled by no other plan. T would make an exception to this in the proper use of the irrigator, to which I have just alluded. * Gerster, " Aseptic aud Antiseptic Surgery." t Clioyuc, " Antiseptic Treatment of Wouuds." ANTlbi:i'llC SUK-.KKY AND SOMK OF ITS UBSULTR. 1013 Wliile in Edinburgh a little over two years since, I had the privilege of witnessing the practice of that eminent surgeon, Mr. Josepji Bell, whose name is inseparably connected with Edinburgh surgery. Mr. Bell used an irrigator, but so thoroughly and effectively, and apparently with so little trouble, that I am forced to admit that the spray would have been clumsy in comj)arison. When an irrigator is nsed as I saw it used there, it is a matter of indifference what l)ecomes of the spray, the former answering the same purpose. Dr. A. C. Patterson, at a meeting of the Medical Society of GLisgow, when various antiseptic appliances were under discussion — notably, sublimate gauze, just then coming into notice — stated, " that he was still old-fashioned enough to use the spray. His results for the last six months had been 137 operations and one death." In a piivate com- munication lately received from him, he informs me that, by the same means, he has completed 100 consecutive cases of excision of the breast without a single failure. This result requires no comment. On what- ever grounds, then, the spray has been discarded by some, it is still doing useful work. In whatever way an operation may be conducted, I wish to emj»hasise the fact, that no surgical cleanliness can be attained without the use of antiseptics. The more modern term " surgical cleanliness " is synonym- ous with Listerism, because the latter, properly carried out, means the former in its highest sense. It is no unusual thing to tind sui'gical contributions terminate with something like the following : — "Although no antiseptics were used, every care was taken to obtain thf* greatest degree of cleanliness." When pure water does not exist (not available, at any rate, for surgical purposes), it is difficult to see how cleanliness of any description can be attained without antiseptics. They are absolutely indispensable. I do not mean to assert that they are the only important matters connected with wound treatment, but they occupy the first ])lace. The antiseptic surgery practised by myself, and which I will submit for your consideration, is somewhat modified by circumstances. Living as I do in the country, J cannot always command the use of the spray, and since the introduction of sublimate gauze dressing, I use chiefiy the irrigator. It is of this method that I will now speak. I am careful, in wound treatment, to have a definite object in view. Stated briefly, that object is the thorough protection of the wound from all sources of infection, whether arising from the air or from solids or fluids. This, carried out in its integrity, would ensure its speedy and successful healing, without any local septic disturbance or constitutional risk to the patient. It would necessitate a perfsctly aseptic wound, antiseptic surroundings, and efficient drainage. The latter, to my mind, is, next to the introduction of antiseptics, the greatest boon yet conferred on oi)erative surgery. Tlie method J adopt has not the charm of novelty. It is similar to that pursued by the generality of surgeons who practise some form of Listerism on a definite system. Nor is it characterised by extreme simplicity. I mention this, because it is often amusing to hear the complaints against aseptic surgery generally, that it is wanting in this feature. It is either continually forgotten, or altogether ignoied, that the labour spent in a well-nlainied asei)tic operation, however great, is in the end an enormous gain! Tliis is a matter of daily exjteiience, and need not be dwelt upon. 1014 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA Selecting an excision of the breast to illustrate what I have to say regarding -wound treatment, because it is one often performed in country 2)ractice, I would first say a word concerning the preliminary prepara- tions, to which I attach supreme importance.* The part to be operated upon is thoroughly washed with soap and water, and with ether afterwards, if thought desirable. This is followed by washing with carbolic acid solution. Lint, dipped in some of the same, is laid upon the part for a few hours previous to the operation. I cannot too strongly insist, that a vigorous use of the nail brush should precede every operative measure, followed by a washing of the hands in carbolic solution. The same remark applies to ever3-one who may assist. In regard to the immersion of the instruments, carbolic acid solution is the only suitable fluid. Corrosive sublimate, although the antiseptic, is unsuitable from the chemical action it exercises on instruments not nickel-plated. This chemical reaction is also said to alter the quality of the fluid. It makes however, an excellent medicum for the sponges. The strength I use for this and subsequent purposes, is 1-2000. There is one matter apparently not of much moment, but in reality, of very great importance. Nothing is more common at an operation than to see instruments and sponges, when leaving the hands of the operator, put in every conceivable place on the table — on the patient even, instead of being returned to the solution by the hands of an assistant.! Especially is this likely to take place during a protracted and anxious operation. To obviate this, it is well to cover the patient with some impermeable material, previously antisepticised. If this is carefully adjusted, leaving the part to be operated on only visible, it will serve the purpose in view admirably : but it is scarcely necessary to remark, that no precautions for such a purpose ought to be necessary. The removal having been accomplished, how is the wound to be treated l Fii'st, in regard to the htemorrhage. Will we torsion the vessels, or ligature them with catgut 1 I confess that I have never twisted a vessel of respectable size without considerable misgiving for the result, although those continuously doing it speak of it as the more eflectual method of the two. In the hands of the distinguished President of this Congress, torsion has, I believe, attained a perfection rarely equalled. Whatever plan is adopted, the importaiice of stopping every bleeding point cannot be over-estimated. The disadvantages of oozing after an operation, and the collection of blood in the wound, ai*e obvious. It may give lise to tension, requiring the dressing to be interfered with, and if not perfectly aseptic, will cei-tainly decompose. Otherwise, its absorption along with other products will prove harmless, only giving rise to what is known as Yolkmann's "aseptic fever." In an operation of this magnitude, thorough and complete drainage is indispensable. Draining, while imperatively necessary, has unfortunately serious drawbacks. We have to introduce a foreign body into the wound, which is a highly imdesirable |)roceeding. Many attempts have be'Mi made to perfect our drainage material, but with only partial * The preliminaries of wound treatment will be found at some length in Cheyno's- little work. t Gerster, oj). cit ANTISEPTIC SUKCiERY AND SOME OF ITS RESULTS. 1015 success. Ordinary tubing, esi)eciiilly the red variety, holds the first place. Decalcified bone has not realised the anticipations regardinir it, and drainage by horse-hair and catgut have never come into much prominence. Of all kimis of draining material however, I prefer the lattei', because it is fairly effective and perfectly harmless. Unfortunately, it will not drain pus, but blood or .serum ])erfectly. But as the presence of pus in asej)tic wounds is rare, it n)ight have a trial in the first instance. Perfection in drainage will not be attained till we find some sulistance capable of doing so, giving rise to no irritation, and disappear- ing when its functions are fulfilled. In all wounds of the size we are now dealing with, stitches of relaxation should form a feature, be not too numerous, and firndy tied ; and in all aseptic wounds, the sutures for accurately bringing the edges together should be numerous. For both purposes I use chromicised catgut. Sup])Ose the deep and superficial sutures inserted, the hajmorrhage stopped, and the drainage material in position, the wound is then thoroughly irrigated with corrosive sublimate solution ; it is then closed, and the sutures cut short. Finely powdered iodoform, or a mixture of iodoform and bismuth is dusted over it, w hen it is ready for the sublimate gauze dressings. A few layers varied according to circumstances are applied, and ovei-lap the wound for several inches. These, being fixed in position by bandages of the same material, constitute the deep dressing. Over this is placed further layers of gauze, extending widely in all directions, and over all, equable elastic ])i-essure. This may be graduated with such nicety as to give not only the most efficient support to the dressings, but positive comfort to the patient. Pressure ajjplied by means of some elastic substance, has much to do with the success of wound treatment, not only for the reasons just stated, but for the jierfect rest and immobility which it ensures, and which ordinary bandaging is incapable of accomplishing. In a wound treated in the manner indicated, what is there to interfere with its future progress? It is presumed to be thoi'oughly aseptic so far, and protected from all sources of infection. The chief danger undoubtedly lies in the first dressing, and this, other conditions being favourable, should be delayed as long as possible. Possibly, one dressing only will be needed, and that at a time so advanced that no contamination need be feared. Macewen, when discussing the value of antiseptics at a meeting of the Glasgow Medical Society, .said, "that in his last forty consecutive cases of primary amputations, excluding some who died within forty- eight hours after admission, healing took place after one dre.ssing — ^tliat put on at the time of operation. In excision of the knee, he had now no occasion to u.se parafhne or plaster, as the wounds generally healed under a single dre.ssing." I am not aware of any rule as to when the second dressing of an aseptic wound should take place. I would not touch it without some very decided indication. The thermometer might be thought to give some sign, and although a sharp rise is often pre.sent, it generally depends on the absorption of wound products, which are harndcss, because j)ure. This " a.septic fever" then, as it has been termed, is a matter of no moment. "With the exception of pain or tension in the wound itself, or the appearance of discharge external to the dressings, I know of no condition that would justify us in interfering at all. 1016 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Nothing can be more conducive to invite disaster under such circum- stances, than freqvient and consequently meddlesome treatment. An early dressing would require the same scrupulous care as the first. An irrigator must be kept continually playing over the wound, from the time the dressings are removed till their re-application. Should local inflammatory conditions supervene, and whei-e the strict adherence to this routine has to be abandoned, much may still be done to carry out asepticism. This is particularly to be desired, as the disturbance generally depends upon excessive tension, from fluid as yet perfectly free from a trace of decomposition. If the application of heat is called for, whicli it generally is, in addition perhaps to the removal of some stitches, and attention to drainage, I am decidedly against the employment of poultices, as generally understood, of which linseed meal may be taken as the type. They are dirty, inelegant, and above all, fruitful sources of contagion. A suitable number of folds of boracic, carbolised, or sublimated lint apjilied frequently as a fomentation, and covered by any material that will retain the moisture, fulfil every indication. Not only so, but their application is leased on principles, while the former is only the result of a past and present empiricism. From this imperfect sketch, it will be seen that an efi'ort is made to give ]U'actical eS"ect to the great princijjles of IJsterism, viz., the exclusion of active ferments from a wound, or surgical cleanliness, if you will. The diff'erence exists in name only. Anything less would not be much in advance of the suigicai ^^ractice of fifty years ago; while in the direction of more completeness, it is capable of much improvement. The choice of antiseptics is a varied one, but may for all pui-poses be reduced to four — carbolic acid, corrosive sublimate, iodoform, and boi'o- salicylic solution, the latter being a most admirable agent where a large extent of surface has to be dealt with. I would employ carbolic acid almo.st exclusively for cleansing the hands, the parts to be operated on, a;nd the immersion of instruments. Tn this respect it has always stood, and stands now, without a rival. The choice is limited in number, for a very sim})le reason. They are the best that experimental and clinical evidence has yet furnished us. In limiting the ninuber, we become thoroughly acquainted with their individuality, if I may use the term, and attain a correct knowledge of what each is capable of accomplishing.* In this connexion, a curious and to me inexplicable anomaly is far from infrequent. Nothing can be more certain than that two of the substances at least possess aV)Solute and definite powers in relation to micro-organic life; and how constantly do we hear this called in question or denied, l)ecause at times they fail 1 Is it so in medical therapeutics 1 Do we question the specific action of colchicum in gout ? mercury in syphilis 'i salicylate of soda in acute rheumatism 1 or digitalis in certain cardiac conditions, l>ecause in some cases we find them useless and inert? Is it always the fault of the drug, and iiot of the administrator? No condemjiation can alter the fact, that corrosive sublimate and carbolic acid have specific actions in wound tieatment. The truth of this, any one can verify for himself. Comparisons of a like nature might be made in answer to the charge, that they have been productive of fatal results. . Unquestionably, they have. So has chloroform iidialation; so has the * Gerstor, o;>. cit. I t ANTISEPTIC SUKGEKY AND SOME OF ITS KESULTS. 1017 insignificant operation of vaccination, but neitlier will be abandoned on that account. The introduction of corrosive sublimate marks a distinct era in our progress. "Its discovery as an antiseptic, or the very higli order of its j)0wers, are not due to Koch, as many suppose. Eighty years a'-^o, Waterton, the celebrated naturalist, during his wanderings in Soutli America, used it for preserving the skins of animals. A little later Kyan used it for preserving wood for building war ships, from dry rot. In 1865, its antisej)tic powers were tii-st compared with other bodies. In that year. Dr. Angus Smith found that when it was mixed with blood, the amount of imtrefying gases evolved were too minute to admit of determining their quantities ; while, with many other antiseptics, including carbolic, tested under identical conditions, these gases were l)roduced in large quantities." — (McDougall, Glasgow M(^dical Jotirnal). To Koch in Germany, and Lister in England, undoubtedly belont^s the credit of being the means of practically making it available for oui- surgical wants. At the present moment, it is jjre-eminently the antiseptic in wound treatment, and in fact every condition where sepsis lias to be guarded against. A single instance of its power will l)e sufficient. In Huid suitable for the growth of micro-organisms, but treated with sublimate solution, no organisms had aj)peared after it had been kept 182 days. Iodoform is mo.st valuable, either pure, oi- mixed with bismuth. In the minor surgery of countiy practice, its use fultils an acknowledo-ed want. In operations about the anus or genito-urinary organs, it has reall}' no substitute. In cases of supra-pubic lithotomy and extensive jierineal section lately, I used tins substance entirely. In the former there was considerable necrosis of tissue, fiom the action of the urine. Though both advanced in years, free livers, and with a suspicion of kidney disorder, their recovery was j^erfect. The sublimate is quite inadmissible, where there is any indication of kidney disease. Boro-salicylic jtreparations may be used on all occasions, and in any quantity. Although their antiseptic powers are not great, they are often valuable and handy for very large surfaces, Avhere the use of those already mentioned might be attended with risk. Such are some of the means we take to prevent blood-poisonino- a condition absolutely depending on the presence of bacteria in a wound. Whether we regard the jioison as due to the result of their chemical action, and the production of ptomaines, or the entrance of jmtrid matter, of which they form a part, into the blood, matters little. Thev originate in our operation wounds, and it is our duty to prevent theni^, which is the cardinal principle of Listerism. Its chief value lies in its precision, and the unanswerable reasons which can be given for eveiv stage of its process. It seeks to bring surgical treatment into somethiii"- like harmony and definiteness of purpose — a thing of which we must all fed it stands much in need. Surgery is beginning to feel the influence of a power that has raised it, and will continue to raise it, to a higher level. Pre-antiseptic surgery was almost empirical — a gro]»ing in the dark. As a consequence of this, its j)rofessors, even of the most brilliant talents Avere quite unable to look ahead, for the sim])le leason, it was quite impossible to predict how an operation, in the majority of instances at least, would end. The act once committed, was beyond the reach of any 1018 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. controlling power. At the present time, we cannot speak of the results of operations with absolute certainty, it is true ; but we have come very near it. So far as blood-poisoning is concerned (and that is the only condition engaging our attention), with a patient in good health, and surrounded by all the hygienic conditions that modern surgery justly demands, we can now in many cases promise results. And why? Because of the power we possess over septic processes. The limits of this short paper will not allow me to allude to the results which aseptic surgery has accomplished. This is scarcely to be regretted, as they ai-e now matters of history. A study of surgical statistics generally, and those of aseptic surgery in particular, will show the conspicuous superiority of the latter. In a series of 295 opei-ations by myself, the death-rate was only a fraction over 3 per cent. One case alone died from blood-poisoning. Even in spite of Listerism, with all its safeguards, minuteness of detail, and the sustained attention it demands, we have still to face a certain mortality from blood-poisoning. The age of '•' perfect surgical cleanliness," has not yet arrived, nor will it, as long as this scoui-ge of sui'gery follows in our track. That Listerism has stayed its ravages in a remarkable manner, has robbed it of half its terrors, and even shown a way by which it may be eradicated, are facts which do not require to be insisted on, and which few will deny. INDEX. Abdominal Section, Fifty Cases of— F. C. Batchelor Abo (Finlaucl), Hygienic Conditions of — A. R. Spoof Adam, G. R. — Modification of Sims' Operation of Metrotomy Addresses of Presidents of Sections. Sec Presidents of Sections. Allen, H. B. — Typhoid Fever Connected with Milk Supply ^'ariations in Pathological Process in Typhoid Fever Catalogue of Museum of Pathology Specimens and Cases of Hydatid Diser.se . . Alopecia Ai-eata — D. Colquhoun Anesthetics during Labour. — S. Maberly Smith Anatomy and Physiology, Address in — T. P. Anderson Stuart „ ,, Demonstrations, &c. . . Anderson, C. M. — Nasal Calculus from a Girl . . Microscopic Sections of Glioma of Retina Anderson, E. — Menstrual Function Ankle, Compound Dislocation of — H. C. GaiNlc . . Antiseptic Surgery — R. B. Duncan Anthrax in Australia — W. M. Hamlet . . Apostoli's Treatment of Uterine Fibroids — J. Foreman . . Aortic Incompetence and Locomotor Ataxia — D. Colquhoun Ai-mstroug, W. — Lunacy Legislation in Australia Astles, H. E. — Chiau Turpentine in Cancer Astragalus, Fracture of — H. C. Garde . . Asylum Practice, Hospital Methods in — Eric Sinclair Atrophy, Unilateral Renal — T. C. Fisher Aural Disease and Epilepsy — C. L. M. Iredell . . Australian Climates for Consumptives —J. Robertson ,, ,, Discussion in Hygiene Section Australian Lunatic Asylums, Management of — W. L. Clelaud Batchelor, F. C. — Address in Section of Obstetrics and Gynaecology Fifty Cases of Abdominal Section Balls-Headley, W. — Removal of Ovaries and Tubes Bancroft, J. — On Filaria Bancroft, T. L. — Materia Medica of Queensland I'lant^ . . Barrett, J. W. — Nature of Vision in Animals Treatment of Chronic Catarrh of the Middle Ear . . Danger of Eye Operations when Mucocele is Present Value of Redness of the Handle of the Malleus as a Symptom in Diseases of the Middle Ear Bath, Treatment of Typhoid by Cold— F. E. Hare Beri-beri in the Northern Tei-ritory — P. M. Wood Bickle, L. W. — Phlyctenular Conjunctivitis in Erythema Nodum Birch Itch, a Note on the New Zealand — D. Cohiuhoun . . Bird, S. D.— Immediate Treatment of Pleurisy with Effusion Bismuth, Therapeutic Position of — T. Dixson . . PAOB-. 649 702. 159' 175 999 1004 972 691 569 585 797 798 704 300 1009' 522 717 135 • 877' 941 301 895 615 789 77 565- S70 625. 649' 667 49' 927 588 756 777 794 179 54 796 970 99 933 1020 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Blight and Granular Ophthalmia — T. A. Boweu Bone Disease, Specimens of — H. B. Allen Bone Inflammation, Subcutaneous Drilling in — T. N. FitzGerald . . Bonnefin, F, H. — Notes on Typhoid Bowe, F. — Diseases of Polynesians in Queensland Bowen, T. A. — Sandy Blight and Granular Ophthalmia . . Brain, Eemoval of Hydatid Cyst from — J. C. Verco Brain, Injury to Frontal Kegion of the — D. Colquhoun . . Breast, Cancer of. Table of 47 cases — F. Milford Caesarian Section — F. C. Batehelor Cancer of Breast — F. Milford . . Carstairs, J. G. — Etiology of Typhoid . . Catalogue of Museum of Pathology Cerebellar Abscess Trephined — ^H. L. Ferguson Cerebellar Cyst — J. C. Verco . . Cerebellar Disease, Trephining for — H. Maudsley Cerebro-Spinal Fever — W. Fiulay Cerebrum, Evacuation of Abscess in — J. C. Verco and E. C. Stirling Cerebrum, Functions of — Professor Anderson Stuart Chambers, T. — Uterine Pregnancy supervening on Ectopic Gestation Chancre, Resection of Hard — M. Crivelli Cliest, Origin of Form of — Professor Stuart Chian Turpentine in Cancer — H. E. Astles Children, Sunstroke in — W. K. MacEoberts ,, Intestinal Troubles in — W. Snowball . . Cholera Quarantine — K. R. Kirtikar „ ,, Discussion Chyluria and Filarial — J. Bancroft Cleft Palate, a Case of— T. N. FitzGerald Cleland, W. L. — Australian Lunatic Asylums, Management of Climate of New Zealand — D. Colquhoun Climate, Treatment of Phthisis by — D. Turner . . Climatology of Nelson (N.Z.) — J. Hudson Colonies as a Health Resort for Consumptives — J. Carnegie MacMullen Colquhoun, D. — Aortic Incompetence and Locomotor Ataxia Injury to Frontal Region of Brain Phthisis in New Zealand A Note on the New Zealand Birch Itch . . On some Cases of Alopecia Areata and its pi-obable causes Collingwood, D. — Gastro-Enteritis in Children . . Conjunctivitis, Granular — R. B. Duncan Conjunctivitis, Phlyctenular, in Erythema Nodosum — L. W. Bickle Constitutional Factor in Disease — J. Robertson . . Consumptives, Colonies as a Health Resort for— J. Carnegie MacMullen Convergence — M. J. Symons . . Creed, J. M. — Leprosy in its relations to the European Population Australia Cretinism, Sporadic — F. N. Manning .. ,, „ E. C. Stirling •Crivelli, M. — A Note on Pasteur's Methods of IXDEX. 1021 Crivelli, M. — Critical Keview of Resection of Hard Chancre Microbe of GouorrlKea Croup and Diphtheria— J. Janiicsou Cystotomy — A. SlacCorruick . . ,, Supra-pubic, twenty succossfnl eases — H. O'Hara Diphtheria, nature and causes of, and rehxtion to Croup — J. Jamieson „ Notes on— A. Jarvie Hood . . ,, Discussion on Disease, Constitutional Factor in — J. Eobertson Dixson, T. — Druminc : Is there such a body ? .. Probable Therapeutic position of Bismuth . . Drilling, Subcutaneous, in Bone Inflammation — T. N. FitzCierald . . Druminc: Is there such a body? — T. Dixson Duncan, R. B. — Granular Conjunctivitis Antiseptic Surgery and some of its Kesiilts Dyson, T. S.— JIalarial Fevers in Tropical Queensland . . Ear, Middle, Redness of Handle of Malleus in Inflammation of— J. W. Barrett Ear, Middle. Treatment of Chronic Catan-h— J. W. Barrett Ectopic Gestation followed by Uterine Pregnancy — T. Chambers . . Electricity in Diseases of Women — J. Foreman Elephantiasis in New Guinea — Sir W. MacGregor Epilepsy and Aural Disease — C. L. M. Iredell . . Erson, Leger— Sanitary State of New Zealand .. Execntive Committee, Report of Exercises, as an Aid to Siu-gical Treatment — R. E. Roth Eye, Excision of, followed by Septic Meningitis — J. T. Rudall „ Points in Structure of — Professor Stuart . . ,, Physiological Model to show accommodation, A:c. Eyes, Manifestations of late Hereditai-y Syphilis in — G. A. Syme . . Eye Operations when Mucocele is present — J. W. Barrett Eyelids, Congenital Cyst of — W. Odillo Maher . . ,, Sarcoma of — W. Odillo Maher Faithfirll, R. L.— Notes on the Treatment of some of the more frequently met with Skin Diseases . , Federal Inspection and Quarantine — A. E. Salter Ferguson, H. Lindo.— Cerebellar Abscess treated by Trephining . . Optic Neuritis after Exposure to Heat Resection of Optic and Ciliary Nerves Exhibits by Fetherstou, R. H.— Pilocai-pine in Puerperal Eclampsia . . Fever, Cerebro-Spinal— W. Fiulay Malarial, in Tropical Queensland— T. S. Dyson . . Filaria — Dr. Bancroft Finlay, W.— Cerebro-Spinal Fever Fisher, T. C. — Unilateral Renal Atrophy FitzGerald, T. N. — Inaugural Address by New Operation for Cure of Congenital Talipes Varus and Eqnino-Varus . . 241 620 800 21G '2()0 800 807 814 73 937 933 321 il37 743 1001) (54 794 7yt> (m 717 48 789 485 3 298 769 5«5 586 771 777 767 751 965 545 764 761 731 797 708 139 64 49 139 615 9 316 1022 INTERCOLONIAL MEDICAL CONGRESS OF AUSTRALASIA. Fitzgerald, T. N. — Subcutaneous Drilling in the Treatment of Bone paoi; Inflammation . . . . , . . . , . 321 Cleft Palate .. .. .. .. ..326 Foreman, J.— Electricity in Diseases of Women . . . . . . 717 -Garde, H. C. — Compound Dislocation of Ankle . . . . . . . . 300 Gardner, W. — Loreta's Operation . . . . . . . . . . 301 Surgery of the Kidney . . . . . . . . . . 305 Surgical Treatment of Hydatid Disease , . . . . . 345 Twisting of Pedicle in Ovarian Tumours . . . . . . 674 ■Gastro-Euteritis in Children — D. Collingwood . . . . . . . . 984 ■Gastrolobium and Oxylobium, Poisonous Action of — J. C. Eosselloty . . 931 'Gastrotomy and Gastrostomy — Sydney Jones . . . . . . . . 223 Glaucoma Fulminans — G. Thon . . . . . . . . . . 781 Glaucoma, Not Believed by Iridectomy — J. T. Rudall . . . . . . 768 Glioma of Retina — C. M. Anderson . . . . . . . . . . 798 Goitre, Specimens of — H.B.Allen .. .. .. .. .. 1002 Gonorrhcea, Microbe of — M. V. Crivelli . . . . . . . . 020 •Gout — J. Robertson . . . , . . . . . . . . . . 77 Governor's Address — Sir H. B. Loch . . . . . . . . . . 2 Grant, D. — Raynaud's Disease . . . . . . . . , . 129 JTERCOLOyiAL MEDICAL CONGRESS OF AUSTRALASIA. Pneumatic Therapeutics— V. Marano . . Pneumonia attended with Mania in Polynesians — F. Bowe Polynesians, Diseases of, in Queensland — F. Bowe Post-nasal Growths — T. K. Hamilton . . Poulton, Dr., Presentation to .. Practitioners, Unqualified ,, ,, Discussion concerning Pregnancy, Complicated with or Associated with Ovarian Disease — T. Eowan ,, Extra-Uterine, Two Cases Successfully Treated — R. Worrall ,, Laparotomy during — F. C. Batchelor ,, Uterine, Supervening on Ectopic Gestation — T. Chambers Premier's Address of Welcome — Hon. D. Gillies President of Next Session, Election of . . President's Inaugural Address — T. N. FitzGerald Presidents of Sections, Addresses of — Anatomy and Physiology — T. P. Anderson Stuart Diseases of Children— W. Snowball Diseases of the Eye, &c. — M. J. Symons Diseases of the Skin— J. P. Ryan . . Hygiene— H. N. MacLauriu Medicine— W. F. Taylor . . Obstetrics and Gynaecology — F. C. Batchelor Pathology— W. Camac Wilkinson . . Psychological Medicine— F. N. Manning Pharmacology— F. von Mueller Surgery— E. C. Stirling .. Psychology, Address in— F. N. Manning Puerperal Eclampsia, Pilocarpine in— R. H. Fetherston . . Puerperal Fever, in Relation to Midwifery Practice— J. C. Verco . . ,, Discussion concerning Pylorus, Dilatation of, Loreta's Operation— W. Gardner .. „ Resection of, by New Method— H. W. Maunsell Quarantine, Federal— A. E. Salter Quarantine for Cholera— K. R. Kirtikar Queensland, Malarial Fevers in Tropical— T. S. Dyson . . Queensland Plants, Materia Medica of— T. L. Bancroft . . Race and Insanity in New South Wales— C. Ross Ralph, T. S. — A New Mode of Administering Protoxide of Iron Raynaud's Disease — D. Grant Receptions and Entertainments Renal Atrophy, Unilateral- T. C. Fisher Report of Executive (Committee Robertson, J.— History of Typhoid Fever in Victoria and its Etiology Importance of Constitiitional Factor in Disease Ross, Chisholm — Race and Insanity in New South Wales Rosselloty, J. C— Poisonous Actions of Gastrolobium and Oxylobium Roth, E. E. — Instrument for Recording Lateral Curvature Special Exercises as an Aid to Surgical Treatment . . Rowan, T. — Pregnancy Complicated or Associated with Ovarian Disease PACE 93 60 59 782 31 31 567 645 664 654 697 9 30 9 569 981 721 961 401 34 625 591 816 909 197 816 708 684 695 301 241 545 539 64 927 849 958 129 21 615 3 149 73 849 931 299 298 645 102 PAfJi; Rudall, J. T. — Glaucoma in whicli Iridectomy seemed Hurtful .. .. 7(58 Septic Meningitis after Excision of Suppurating Eyeball . . 769 Eyan, J. P.— Open-air Treatment of Phthisis . . . . . . . . 90 Address in the Section for Diseases of the Skin . . . . 961 A Case of Ichthyosis . . • • . . . . . . 977 On a Case of Acquired Syphilis in a Child Three Years Old . . 994 Salter, A. E.— Federal Quarantine . . . . . . . . . . r,i5 Sanitary Condition of Colonies. — Discussion .. .. .. .. o67 „ ,, New Zealand — Leger Erson .. .. .. 485 ,, State of New South Wales— J. Ashburton Thompson .. .. 434 Scott, G. A. — Notes on Lateral Spinal Curvature . . . . . . 264 Scrofula and Tubercle — J. Eobertson . . . . . . . . . . 75 Sectional Meetings of Section of Hygiene . . . . . . . . 565 Session, Date and Place of Thu-d, lixed . . . . . . . . 30 Sewage Disposal— W. F. Taylor . . . . . . . . . . 490 Sewage Farms, Typhoid Germs in — A. Shields . . . . . . . . 562 Shields, A. — Typhoid Germs in Sewage Farms . . . . . . . . 562 Sinclair, Eric — Extension of Hospital Methods to Asylum Practice . . 895 Skin, Diseases of — Presidential Address^ J. P. Ryan .. .. .. 961 „ ,, Notes on Treatment of some — E. L. Faithfull .. .. 965 Skin Eruptions complicating Urethritis — R. A. Stirling . . . . . . 974 Smith, Patrick — Inebriety, its Etiology and Treatment . . , . . . 860 Smith, S. Maberly—AniBsthetics during Labour .. .. .. 691 Smith, W. Beattie — Housing of Insane in Victoria, with special reference to Boarding-out . . . . . . . . . . . . . . 898 Snake-bite, Notes on Two Cases of— J. S. Thwaites . . . . . . 945 Snowball, W. — Address in Section for Diseases of Children . . . . 981 SpeciaUsm, Benefits of — M. J. Symons . . . . . . . . 721 EvUs of —D. Turner .. ., .. .. ..551 Spinal Curvature, Notes on Lateral — G . A. Scott . . . . . . 264 ,, „ Instrument for Eecording Lateral — E. E. Eoth.. .. 299 Spoof, A. R.— Hygienic Conditions of Abo (Finland) . . . . . . 554 Springthorpe, J. W. — Hepatic Element in Disease , . . . . . 67 Hygienic Conditions in Victoria . . . . . . 465 Locahsation in Nervous Diseases .. •. .. 121 Nervous Substratum of Influenza . . . . . . 101 Notes on Typhoid Fever . . . . . . . . 173 State Medicine in New South Wales — C. W. Morgan . . . . . . 456 ,, ,, Western Australia— J. E. M. Thomson .. .. 489 State Medical Practitioners — J. T. Mitchell . . . . . . . . 515 Stenhouse, W. M. ^Dosage of Iodide of Potassium, with special reference to Psoriasis . . . . , . . . . . . . . . 938 Stirling, E. C. — Address in Section of Surgery .. .. .. 197 On Sporadic Cretinism . . . . . . . . 840 Stu-ling, E. C, and Verco, J. C. — Abscess in Cerebrum . . .. 280 Stu-Ung, E. A. — Notes on some Skin Eruptions, complicating Urethritis . . 974 An anomalous case of acquired Infantile Syphilis . . 991 On a case of Syphilitic Dactyhtis in a Child . . . . 992 Stuart, Professor Anderson— Address in Section of Anatomy and Physiology 569 l)pmonstrationfi and Exhibits .. .. 585 2u 2 1028 INTERCOLONIAL MEDICAL CONGRESS OP AUSTRALASIA. I'AGE Sulphate of Iron, External use of— Colin Henderson . . . . , . 943 Sunstroke in Children— W. K. MacRoberts . . . . . . , . 144 Supra-pubic Cystotomy — A. MacCormick . . . . . . . . 248 ,, Lithotomy — J. Tremearne .. .. .. .. 257 Syme, G. A. — Ocular Manifestations of late hereditary Syphilis .. .. 771 Symons, M. J. — Address in Section for Diseases of Eye . . . . . . 721 On Convergence . . . . , . . . . . 725 Syphilis among Polynesians in Queensland — F. Bowe . . . . . . 61 „ Ocular manifestations of late hereditary — G. A. Syme . . . . 771 „ Acquired in a Child three years old — J. P. Ryan . . . . 994 ,, an anomalous case of acquired Infantile — R. A. Stirling . . . . 991 Syphilitic Dactylitis in a Child— R. A. Stirling .. .. .. ..992 „ Keratitis (inherited) — J.Jackson .. .. .. .. 773 ,, Organs and Growths, Specimens of — H. B. Allen . . . . 1002 Tait's Operation — F. C. Batchelor . . . . . . . . . . 651 Talipes, New Operation for Congenital — T. N. FitzGerald . . . . 316 Taylor, W. F.— Address in Section of Medicine . . . . . . 35 Sewage Disposal . . . . . . . . . . 490 Thanks, Votes of .. .. .. .. .. ., .. 32 Thomas, J. Davies — Age and Sex in Hydatid Disease . . . . . . 342 Bilirubin in Hydatid Cysts . . . . . . 391 Geographical Distribution of Hydatid Disease . . 328 Operative Treatment of Echinococcus Cysts . . . . 352 Treatment of Liver Abscesses by Free Incision . . 230 Thompson, J. Ashburton — A Record of the Present Sanitary State of New South Wales . . . . . . . . . . . . . . 434 Thomson, J. R. M— Hydatids in Zygomatic Fossa . , . . . . 385 State Medicine in Western Australia . . . . 489 Thon, G. — Glaucoma Fulminans .. .. .. .. .. 781 Thwaites, J. S. — Notes on two cases of Snake-bite . . . . . . 945 Tinea desquamans— Sir W. MacGregor . . . . . . . . 46 Tonsilhtis, Follicular, in Children, its correlation with other zymotic diseases — A. Honman . . . . . . . . . . . . . . 995 Tremearne, J., Supra-pubic Lithotomy .. .. .. .. 257 Tubal Disease— F. C. Batchelor . . . . . . . . . . 633 Tumours, Pathological Specimens of— H. B. Allen .. .. .. 1003 Turner, D. — Evils of Specialism .. .. .. .. .. 551 Treatment of Phthisis by Climate . . . . . . . . 87 Twisting of Pedicle in Ovarian Tumours — W. Gardner . . . . . . 674 Typhlitis, Seven Cases of —A. S. Joske . . . . . . . . 71 Typhoid Fevkk, Meeting and Papers concerning . . . . . . 149 Cold Bath Treatment— F. E. Hare . . . . . . . . 179 Connection with Milk Supply— H. B. Allen . . . . . . 159 Discussion concerning . . . . . . . . . . • • 188 Etiology of Typhoid — J. G. Carstairs .. .. .. .. 155 History of an Epidemic — A. V. Henderson . . . . . . . . 169 History of Typhoid in Victoria and its Etiology— J. Robertson . . . . 149 Incubation Period — J. C. Verco . . . . . . . . . . 172 Notes on Typhoid and its Treatment — F. H. Bonncfin . . . . 185 Notes on Typhoid — J. W. Springthorpe . . . . . . . . 173 INDEX. 1029 Typhoid Fever { Continued) — page Resolutions concerning . . . . . . • • . . . . 15)5 Variations in Pathological Process — H.B.Allen .. .. .. 175 Typhoid Germs in Sewage Farms — A. Shields . . . . . . . . 562 Unqualified Practitioners, Resolutions concerning . . . . . . 31 Uterine Myomata, Removal of —Sydney Jones .. .. .. .. '2'2S Ventilation, Principles and Practice of — W. V. Jakins . . . . . . 558 Verco, J. C— Case of Cerebellar Cyst . .. .. .. ..117 Diffuse Suppurative Periostitis almost without Necrosis . . 277 Hydatid of Brain, Removal .. .. .. .. 377 Incubation Period of Tyjihoid Fever . . . . . . 172 Puerperal Fever and Midwifery Practice . . . . . . 684 Verco, J. C. and Stii-ling, E. C. — Abscess in Left Middle Cerebral Lobe, evacuation by operation . . . . . . . . . . . . 280 Verco, J. C. and Lendon, A. A. — Multiple Hydatid Cysts treated by Thoracic Incisions . . . . . . . . . . . . • . 386 Victoria, Hygienic Conditions in — .T. W. Si)ringthorpe . . . . . . 465 Vision in Animals, Nature of — J. W. Barrett . . . . . . . . 588 Votes of Thanks . . . . . . . . . . . . . . 32 Westerly Winds of Winter in relation to Disease — F. Milford . . . . 512 Western Australia, State Medicine in — J. R. M. Thomson . . . . 48',( ,, ,, Ophthalmic Work in— J. W. Hope .. .. .. 752 Whitcombe, W. P. — Treatment of Hydatids by Injection of Permanganate of Potash . . . . . . . . . . . . . . 389 Whittell, H. T.— Typhoid and Milk Supply . . . . . . . . 188 Wilkinson, W. C. — Addi-ess in Section of Pathology . . . . , . 591 Williamson, W. C. — Training of Nurses and Attendants in Hospitals for the Insane . . . . . . . . . . . . . . 887 Wood, P. M. — On Beri-beri in the Northern Territory . , . . . . 54 WooUey, G. T. — Congenital Phimosis and Adherent Prepuce . . . . 234 Worrall, R. — Two cases of Extra-uteiine Pregnancy . . . . . . 664 Yaws, in New Guinea — Sir W. MacGregor .. .. ,. .. 47 SllLLWtLL AND Co., I'lUSTtlW, lUJA CuLLINS STREET, MtLBULKNK. A^ 'i^ "t'^>*^_,v.. j.-^: ':vj-' ^T^N^ A^i.,>*^ j>\i, x j'Vt r' ^ ' .-wv. j v/. -y-: ,:f^^i;^;^^'^ < >t3'i:v -A mi.