OF-CALIFO/?^ ^AE-UNIVER% ^UNIYEMjfc. ^lOS-ANCEL^. ^ '**' V S?i ^^^ t/^v^$ i I rZ 13 1 1 i o AOS-ANCElfr, % 5 = r ^r L.OF-CAL! fc I 3 ,\\\E UNIVERS^ I I lOS-ANCEtfj> r* 5 =3 2 ? -x AV\E-l'NIVERS/A. i **JP^< .^ ^ft\rtiNss\\^ MORE SECRET REMEDIES. WHAT THEY COST & WHAT THEY CONTAIN BASED ON ANALYSES MADE FOE THE BRITISH MEDICAL ASSOCIATION, SECRET REMEDIES SECOND SERIES. LONDON : BRITISH MEDICAL ASSOCIATION, 429, STRAND, W.C. 1912. COPYRIGHT. 771 TABLE OF CONTENTS. PAGE CHAPTER I. Remedies for Rheumatism, Gout and Neuralgia ... 1 ,, II. Preparations for Eczema and other Skin Affections 30 ' ,, III. Nerve Tonics and " Elixirs of Life " 44 ,. IV. Medicines for Coughs, Consumption, Catarrh etc. ... 71 ,, V. ,, Indigestion, Constipation, etf. ... 87 VI. Kidney Medicines 102 ., VII. Obesity Cures, and a "Flesh Producer" 112 ,, VIII. Medicines for Alcoholism and for the Tobacco Habit 128 IX. Soothing Syrups for Infants 147 ,, X. Medicines for Epilepsy 152 XI. The " Tremol Treatment " for Bad Legs 167 ,, XII. The " Crimson Cross Remedies " 178 ,. XIII. Medicines for Amenorrhoea, etc. 184 XIV. Wallace's Specific Remedies "An Absolute System of Medicine" 210 ,, XV. Preparations for the Hair 222 ,, XVI. Some Miscellaneous Medicines ... 231 ,, X VII. Unqualified Practice through the Post 241 ,, XVIII. The Advertising of Proprietary Medicines 252 ,, XIX. The "Expert " behind the Proprietary Medicine ... 256 ,, XX. Some Echoes of Volume 1 259 INDEX . 265 PKEFACE. The publication by the British Medical Association under the title ' ' Secret Remedies : What they Cost and What they Contain " of the results of a series of analyses of some of the most advertised of the many proprietary medicines put forward for the cure of disease, has perhaps done more than anything else to open the eyes of the public, the authorities, and the Legislature to the true facts in regard to the nature of such articles and of the enormous traffic that goes on in them. At the time of the publication of this second volume, a public inquiry into the matter by a Parliamentary Committee has just been opened, with a view to deciding on what alterations of the law are necessary or desirable. The present state of the law in regard to the matter, and of its administration, undoubtedly leave room for much amendment. But the surest enemy of quackery in this department is increased publicity in regard to the facts, and the recognition by the public of the great disparity that exists in many cases between the actual composition of many nostrums on the one hand, and the extravagant claims that are made for their curative powers on the other. As a further contribution to a general enlightenment on the subject, the British Medical Association publishes in the present volume the results of a further series of analyses of proprietary medicines which have been carried out for the purpose, together with extracts from the statements of the proprietors of the medicines. The number of those at present existing is so vast that it is only possible to deal with comparatively a few, and these have been selected, as a rule, as being some of the most widely advertised or the most largely sold. It will be recognised at once that there is a very wide variation in the degree of exaggeration in the claims put forward. In a few cases a small minority the advertise- ments appear to consist of very little but an indication of the disorders for which the medicine is recommended. At the other end of the scale there are nostrums put forward with the greatest assurance for even the most serious disorders, including consumption, smallpox, cancer, etc., etc., and in many cases one and the same article is asserted to be a cure for almost every disease to which the human body is liable. As a rule, the more extravagant the claims made, the more surely does the composition of the article, as revealed by analysis, show it to be of little or no value, if not even harm- ful, for the diseases named. Between these extremes, of the modest proprietary medicine more or less of the nature of a harmless domestic medicine on the one hand, and the most fraudulent quackery on the other, are to be found all gradations. The medicines described in this book have not been chosen as inclining more in one direction than the other, but include the various grades. From the facts stated the reader will be able to draw his own conclusions; it has not been necessary, as a rule, to express opinions on the articles described, a juxtaposition of the claims made and the facts shown by analysis being sufficient. The analyses here published have been made with the greatest care during the last few years. Since it is open to the maker of a proprietary medicine to alter its composition at any time without warning (and very great alterations have been proved in some cases), it is, of course, possible that some of those described may have been altered since the analyses were made, though there is no reason to suppose that such has been the case. It is desirable to repeat here the caution that was expressed in the first volume : most of the active substances employed in medicine can be detected with i certainty, even in complex mixtures, by sufficiently pains- taking work on the part of the analyst ; but this is not the case with preparations of some organic drugs, usually of vegetable origin, that have never been fully investigated, and especially with mixtures of the extracts of several vegetable drugs; in such cases analysis can only give approximate results, and constituents having no well- defined characters may escape detection. Since the maker of a secret medicine is in no wise limited to the Pharma- copoeia or to drugs in ordinary use, but may employ, for example, a mixture of extracts of a dozen plants, none of which possesses any medicinal virtue or is recognised as a drug, it is no matter fo" surprise if all the constituents of a nostrum cannot be named as the result of analysis. But if it is remembered that the active ingredients of most sub- stances having medicinal properties possess well-defined characters by means of which they can be identified, it will be seen that the limitations of the powers of analysis here referred to are of comparatively little importance in regard to exposing the essential nature of a given medicine, or substance put forward as such. The figures given in this book as the " estimated cost of ingredients " of the various articles refer only to the ingredients, the cost prices being taken from a wholesale druggist's list; nothing is allowed for the cost of making up the ingredients into the form in which they are sold, or for bottles, boxes, packages, etc. Where the results of analysis are not sufficiently definite for the cost of ingredients to be estimated with reasonable fairness, the figure is omitted. Dr. F. Zernik, of Berlin, has continued the publication in the Deutsche Medicinische Wochenschrift of the results of his analyses of various nostrums sold in Germany, and some of his results are here included. MORE SECRET REMEDIES, WHAT THEY COST AND WHAT THEY CONTAIN. CHAPTER I. REMEDIES FOR GOUT, RHEUMATISM, AND NEURALGIA. The medicines described in this chapter include some of those most widely advertised for the treatment of these complaints. They show a great variety in the methods of treating them, including as they do powders, pills, tablets, drops, and mixtures to be taken ; liniments to be applied externally (one of these being also taken internally), paint, ointment, and plasters to be stuck on to the soles of the feet. The medicaments employed also vary much, but for the most part consist of articles in common use. The adver- tisements are in several respects instructive ; for example, there is undoubtedly a prejudice among the more ignorant section of the public in favour of drugs coming from other and less civilised countries where they have been discovered by " natives," or introduced in some other way than through careful experimenting, and some of the statements made are clearly intended to turn such prejudices to account. Thus in one case it is stated that the discoverer " went back to the heart of Nature in an endeavour to wrest from it the secret of an ideal liniment. In the course of his searches he was favourably impressed with the healing properties of many herbs used by native tribes," etc. ; in another, " this wonderful preparation is the discovery of a Hindu doctor in the Himalayan Mountains." In their varied forms of appeals to " Nature " some of the advertisers do not hesi- tate to ascribe high intelligence to the medicines or to parts of the body other than the brain. Thus one states that No one can reasonably deny an instinctive knowledge anc a physical power exerted in the stomach by a conscious principle which selects and rejects, and which in its natural purity may be ranked as a nerve of sense " ; another that " Immediately the liniment has been applied it sets out upon its message of discovery and healing, travelling with light- ning rapidity to the seat of the trouble " ; yet another calls his ^reparation " A subtle extract from the vegetable king dom, the hidden fire or life of plants and flowers, the ' Quin essence of Life.' ' Among these articles, as in most other groups of nostrum the claims made by rival proprietors are mutually exclusive those dealt with in this chapter include the following : " Greatest and latest discovery in medicine .... there is nothing known in medicine which will compare with it"; "the only efficient remedy ever discovered for these disorders"; "the finest cure for these complaints," curing "when all other remedies fail"; "we guarantee magic foot drafts to cure any case of rheumatism " ; "it is the one remedy that achieves a complete and permanent cure "; "the most effective scientific remedy." Obviously, such claims cannot all be true. Most advertisers of proprietary medicines seem unable to resist dragging in references to the medical profession into their advertisements. There are two principal ways in which this is done : the one is to claim to be receiving the support and recommendations of medical men, and the other is to vilify and slander them as rogues and fools, or both. These two methods are both illustrated here; the former includes " highly endorsed by the leading medical profes- sion " and "physicians are already using them in their regular practice, and recommending them"; the latter is exemplified by " certain medical men have done their best by tongue and pen to persuade the public that Box's Golden Fire is poisonous .... Those who raise the cry of f ' poison ' are wholesale traffickers in the same it is their stock-in-trade ; poisons bring grist to their mills, while the poor victims who swallow them perish by thousands." It is hardly necessary to remark that statements of the former kind are as a rule just as baseless as those of the latter. One preparation described below Bengue's Balsam ^cannot be properly described as a " secret remedy," since -the principal constituents are mentioned on the label; Seeing, however, that it is advertised in somewhat the same /ay as others, it is useful to include it here. , DR. HOFFMAN'S RHEUMATIC POWDERS. These powders are supplied by " The International Chemical Co.," from an address in London. They are advertised in the following terms : Greatest and latest discovery in medicine. Dr. Hoffman's Celebrated Rheumatic Powders. Great German Rheumatic Cure. Will cure permanently all forms of Rheumatism, Gout, Neuralgia, Sciatica, Excess of Uric Acid, etc. Highly endorsed by the leading Medical Profession, Analytical and Con- sulting Chemists, and general public in all parts of the world. Contain absolutely no injurious drugs, poison, or any kind of Narcotic. Its manufacture is based on scientific principles. Relief ia felt after the First Dose. There is nothing known in medicine which will compare with it. A circular enclosed in the package contained statements similar to the above, accompanied by a so-called " analysis " in the following terms : I hereby certify that " Dr. Hoffman's Rheumatic Powders " have been tested in these laboratories, the data obtained being of a most satisfactory character, and indicating them to be judicious and skilful preparations that are well suited for the purposes for which they are designed. They are valuable powders for rheumatism, gout, and kindred complaints. These powders are free from narcotics, poisons, or undesirable constituents, but are powerful uric acid solvents. I consider them to 'be perfectly safe, reliable, and effective medicines. This recommendation, or testimonial, bears the name of an individual who has made himself conspicuous by giving such puffs under the guise of analyses ; hie name ifi followed by a long paragraph setting forth his title to speak with authority, com- mencing with " Ph.D.," and concluding with " Ph.D., etc.," A2 but with no mention of the university which conferred this dupli- cate degree. Such distinctions as " author of . . . . The Physiology of the Invertebrate,' ' Respiratory Proteids,' etc. Analytical Chemist, Assayer and Chemical Engineer, Consulting Chemist, and Expert Adviser to Foreign Govern- ments, Corporations, Collieries, Companies, Pharmaceu- tical and Chemical Manufacturers; .... Bacteriological and Agricultural Expert," are no doubt intended to display his ability to pronounce with authority on the merits of powders for rheumatism or on any other subject whatever. The powders are supplied in boxes at Is. l^d. and 2s. 9d. A Is. IJd. box was found to contain 12 powders. The directions Take one powder every three or four hours; place on the tongue, and wash it down with a draught of water. It would appear that the amount taken at one time is not regarded as of great importance, as the powders in one box varied in weight from 11.3 to 20.8 grains, the average of the 12 being 15.8 grains. Analysis showed the powder to have the following composition : Acetyl-salicylic acid 66.4 per cent. Phenacetin 11.4 Caffeine 1.3 ,, Sugar .' 20.1 Moisture 0.8 Acetyl-salicylic acid is also known by the shortened name of the B.P. Codex, acetosalic acid, and by the trade names Aspirin, Xaxa, etc. The estimated cost of the materials for 12 powders is Id. EADE'S GOUT AND RHEUMATIC PILLS. These pills are supplied by a firm in London. In an advertise- ment it is stated that they instantly relieve and rapidly cure the worst form of gout, rheumatism, rheumatic gout, pains in the head, face, and limbs. The extracts which follow are from a circular enclosed in the package with the pills: They are specially recommended to the afflicted, with confidence arising from experience, as one of the valuable results of the improved state of medical science, and the only efficient remedy ever discovered for these disorders. The never-failing effect* of Eade's Gout and Rheumatic Pills in curing these distressingly painful diseases have secured to them a celebrity un- equalled by any medicine of past or present times. They not only give relief in a few hours where the patient has been driven to madness by the horrible, excruciating tortures of this disease, but restore to perfect health in an inconceivably short space of time in most cases giving relief from the intolerable pain in one or two hours ; one bottle will frequently carry off the attack in two or three days, even when the patient has kept his bed for as many weeks, and sometimes months. These Pills have repeatedly succeeded after all the usual internal and external remedies have failed ; and it is their peculiar property that the first dose completely arrests the frequent tendency of those diseasea to attack some vital part while, if attacked, the symptoms are immediately and effectually removed. The pills are supplied in bottles at Is. Hd. and 2s. 9d. ; a Is. ld. bottle was found to contain 18 pills, and a 2s. 9d. bottle 60 pills. The directions are: " Take one pill three times a day, and two at bedtime ; fo delicate females and weak persons, one pill night and morning." The pills were not coated, as ordinarily understood, but had a thin irregular layer of adherent powder, which proved to be carbonate of magnesia ; the average weight of one pill was 5.4 grains. Analysis showed the presence of aloes, powdered colchicum corm, and extractive, with cane sugar, glucose, gum and dextrin, various characters indicating that the sugars were added in the form of treacle ; the amount of colchicine was determined (and the alkaloid identified) and was found to be considerably more than would be proper to the amount of corm present, and this fact and the presence of an extract pointed to extract of colchicum being present as well as the corm. The amounts of the different constituents were determined as accu- rately as possible ; the amount of aloes, not being determinable with any exactness, was arrived at by comparing the pills by various tests with a mass of known composition. The formula was found to be approximately as follows : Barbadoes aloes lOpercent. Extract of colchicum 18 Powdered colchicum corm 35 Treacle 27 Gum and dextrin ....: 10 Estimated cost of materials for 18 pills, |d. ; for 60 pills, 2|d. URICURA DROPS AND LINIMENT. These preparations, also known as Hammond's Specifics, are made by a firm in Glamorganshire. An advertisement in- quires : Have you tried to eliminate the cause of Rheumatism, Gout, Lumbago, and Sciatica? Uricura Drops will do this for you, being the finest cure for these complaints. The price of each is Is. IJd. A bottle of the drops contained half a fluid ounce, and of the liniment 4 fluid ounces. On the package of the former appears : N.B. In conjunction with the drops it is strongly recommended to use Uricura Liniment. And on the package of the liniment : N.B. It is strongly recommended that for Rheumatiem, Lumbago, ai.d Sciatica, Uricura Drops be taken in conjunction with the Liniment. In a circular enclosed in each package it is stated that : " Uricura " Liniment and Drops (Hammond's Specifics) Cure Rheuma- tism, Gout, Sciatica, Lumbago and Neuralgia When All other Remedies fail. These invaluable preparations have permanently cured many bad cases of from One to Twenty Years' standing. They give immediate relief, and effect a Cure quickly if Regularly and Persistently used as directed. . . . For Colds ; n the Cheet, Sore Throat, and Swollen Glands, nothing better than the Liniment can be used. Athletes and others will find the Liniment a most efficacious remedy for Sprains, Bruises, Stiffness and Cramp. It has been used with remark- able results by leading Football Players. Uricura Drops. The directions are: Dose. Four Drops on sugar, night and morning. Increase two drops each day up to 10, and then reduce two drops each day. Analysis showed the liquid to contain oil of turpentine, terebene, and oil of amber ; no other ingredient could be detected. The proportions of the constituents were ascertained as nearly as possible by analytical methods and checked by aMttpsrieon with made-up mixtures. The approximate formula arrived at was : Oil of amber 5 percent. Terebene 47.5 Oil of turpentine 47.5 Estimated cost of ingredients of half a fluid ounce, Jd. Uricura Liniment. The directions are: To be gently rubbed in for 10 to 15 minutes, night and morning. The liniment consisted of a partly separated emulsion, which was found to contain oil of turpentine, acetic acid, ammonia, alcohol, egg-substance (as emulsifying agent), and water; a trace (under 0.01 per cent.) of alkaloid was found, but this did not possess any properties by which it could be identified, and may have consisted of bases derived from the egg. The acetic acid and ammonia of course combine, but the former was in excess and the liniment moderately acid, about one-fourth of the acetic acid being in the free state. The quantities of the different ingredients were determined (the egg-substance only approximately) and the formula arrived at was as follows : Oil of turpentine 42 parts (by measure) Acetic acid (B.P.) 10 Strong solution of ammonia 2.3 ,, Alcohol 9.0 Egg-substance 2.0 Alkaloid (?) 0.01 Water, to 100 In estimating the cost of ingredients, the alkaloid is neglected ; if the alcohol present were added in the form of rectified spirit, the cost of the ingredients for 4 fluid ounces would be about Hd. ; but if, as is more likely, " non-mineralised methylated spirit " were used, the different odour and other characters would be covered by the other ingredients, and the cost would be about fd. CHAMELEON OIL. This is made by a limited company giving an address in London. It is advertised as " The Only Perfect Liniment," but the directions show that it is intended to be taken internally as well as applied externally. Besides being recommended for human patients, it is described as " The Best Veterinary Medicine Known." It is stated on the package that: Chameleon Oil Eelieves and Cures Rheumatism, Sciatica, Lumbago, Neuritis, Neuralgia, Toothache, Headache, Earache, Backache, Colds, Sore Throats, Sprains and Strains, Stiff and Swollen Joints, Chilblain*, Chapped Hands, Insect Bitee, etc., etc. A pamphlet enclosed in the package gives further particulars ; paragraphs headed " The Story of its Birth " and " Discovery of an Ideal Liniment " do not actually give much information, but the references to the heart of Nature and herbs used by native tribes seem to indicate a method of discovery common to a very large number of nostrums. The following are extracts from these paragraphs: When a Eoman Scholar coined the word " Liniment " which, literally translated, means "to anoint," he had in mind the germ idea of what a perfect liniment should be. In his day the physician anointed his patient with a healing balm which had the magical effect of curing mus- cular trouble without the aid of that tiresome modern invention massage. Such a thing was totally unnecessary with the Romans, who possessed a supreme knowledge of the curative action of simple herbs upon the human frame. . . . But the priceless secret of that painless balm was lost, and so it happens, at the present day, when an embrocation or a liniment is mentioned one instantly conceives of some crude preparation which must be rubbed into the skin violently. ... it was left to Dr. Chas. F. Roberts to bring the word back to its original meaning, as being an ointment whose sole method of action would consist of simply anointing the affected part, and thus painlessly effecting the cure. The task he had set himself was to produce an external appli- cation which, to the two other virtues of being " soothing and pain- killing " should add a third, and the most important of all, " a healing power." As an advanced medical man he realised that the ideal of the healing art should be to relieve human pain by natural means. And so, like the ancient physician, he went back to the heart of Nature in an endeavour to wrest from it the secret of an ideal liniment. In the course of his searches he was favourably impressed with the healing properties of many herbs used by native tribes, because being a rational person he believed, like the late Rev. Charles Spurgeon, that there was a deal to be gained from the use of "sanctified commoneense," which, after all, is the sum of a man's own tried and trusted experience. Armed with this knowledge, which he further tested by very careful laboratory research, his industry was at length rewarded in finding a perfect liniment with the treble merit of being " healing, soothing, and pain-killing," the result of which is embodied in Chameleon Oil Liniment. The action of Chameleon Oil is simplicity itself. Immediately the Liniment has been applied it sets out upon its message of discovery and healing, travelling with lightning rapidity to the seat of the trouble. This found, it restores to the affected part all that pristine freshness which pain and suffering has caused it to lose, quickens the action of the blood, and renews the patient's vitality. ... The principle of Chameleon Oil Liniment ma? be summed up in a few words it releases those healing power, which nature itwlf hw set in th. human body in order 'o overcome the conrtant wastage aad ravagaa of disoaie. The general directions are: Shake Hie botklo thoiouftkly until the eonUnto hwome cream coboxw* Rub the Oil gently into the affected part (use plenty of the Oil) until the pores of the skin refuse to take any more and sweating begins ; then cover with a layer of wool, flannel, or other porous material, and fix with a bandage. FOE STRONGER EFFECT, wash affected part with hot water and apply Oil as above after drying. FOR VERT POWERFUL EFFECT, wash first with very hot water, apply Oil as above after drying, and bandage with flannel or absorbent cotton wool soaked in the Oil or solution of it. Keep on bandage as long as possible ; note that if kept on too long it will raise a blister. Special directions are given for its use in various complaints. The following will serve as a sample : FOR COUGHS AND COLDS. FOR COLD ON THE CHEST. Rub the throat, chest, and the back between the shoulder blades thoroughly with the Oil, and while the skin is still moist apply a fold of warm flannel ; take 15 to 20 drops of the Oil in a little sweetened water, or gruel, at bedtime. FOR CATARRH OR COLD IN THE HEAD. Mix one part of the Oil with eight parts of warm water, gargle the throat, inhale the fumes up the nostrils, and a few applications will cure. FOR CONTINUED COLDS. Rub the chest thoroughly every night with the Oil, and cover with a piece of flannel. Take 15 drops of the Oil in a wineglassful of water three times a day between meals. A Is. ld. bottle which was examined contained 3 fluid ounces, and a 2s. 9d. bottle 9 fluid ounces. The liquid in the two bottles differed in composition ; it consisted of an oily and an aqueous layer, these being in the ratio of 1 to 1.66 in the one case and 1 to 2 in the other. The figures given on the next page refer to the mean composition of the two. The oily layer consisted of a mixture of essential oils ; this was submitted to fractional distillation, and the following were recognised : Oils of turpentine, camphor, mustard, spearmint, pimento, and cassia (or cinnamon). The aqueous layer con- tained some alcohol, free ammonia in considerable quantity, and a resin in combination with ammonia as a soluble resinate ; some of the resin was extracted and examined, but its characters did not agree with those of any single resin in ordinary use ; various mixtures were made and compared with it, but complete agreement in all characters was not arrived at, and it is not possible to speak positively as to the nature of the resins present. By making a mixture of balsam of tolu (4 parts) and storax (1 p*rt), boiling with ammonia, and. filtering from th undis- olved portion, a solution of ammonium reeinafcea was obtained which agreed firly well with that present in the chameleon oil. 10 The amounts of all the other constituents were determined with ae much exactness as is possible with such a mixture, and the following formula was arrived at: Essential oil of mustard 0.75 part by measure Essential oil of spearmint 0.45 Essential oil of pimento 1.5 parts by measure Essential oil of cassia 1.5 ,, Essential oil of camphor 15.0 ,, Oil of turpentine 15.0 Alcohol (90 per cent.) 7.3 Strong solution of ammonia 8.0 Resins (as above) 1.6 Water, to 100.0 A mixture prepared by this formula agreed in physical and chemical properties with the original, except in regard to some minor characters of the resins. Assuming the resins to be of the nature indicated, the esti- mated cost of the ingredients for 3 fluid ounces is 3^ pence if rectified spirit were used, and about 2jd. if non-mineralised methylated spirit were used. LEVASCO. The address given on the package of this article is merely " Levasoo Depot, Dover " ; it is described as " The Great Indian Gout and Rheumatic Cure." The following extracts are from a pamphlet contained in the package : Levasco. This wonderful preparation is the discovery of a Hindu Doctor in the Himalayan Mountains, and if you but give it a trial yon will find yourself Quickly freed from pain and anguish. Levasco is for outward application only, is not an oil, and requires no rubbing, it can be conveniently used at any time. Two or three applications daily Cures the most Chronic cases. . . . Levasco is not being advertised altogether as a business venture, but partly from extreme gratitude of one who for many years was a great sufferer. Levasco has an exhilarating effect on every nerve and muscle similar to a soothing electric current, which diffuses a gentle warmth, goes direct to the pain centres, and gives immediate relief. Levasco penetrates the skin, breaks up the Uric Acid, causing the blood to flow freely, the pain then ceases. Levasco will effect a permanent Cure after years of suffering if the direc- tions are followed and persevered with. . . . Levasco has a pleasant and invigorating odour, the relief is marvellous. Sufferers will sometimes resort to ordinary remedies, and the continual pouring of drugs into an already weakened system will snap the vitality, and cause their lives to become a misery, which brings habitual users to an early grave. 11 Gout cured in a few hours. Apply Levasco upon the affected parts. . . . The first application will give immediate relief. After a few hours' treatment during which time Levasco should be applied as often as possible your Gout will have entirely disappeared. Levasco applied freely will cure Lumbago or Sciatica in one night. Neuritis. Levasco rubbed upon the affected part gives immediate relief, and after three or four applications the pain will be gone, but do not cease using to effect the cure. You must continue to use for a week or two two or three times daily, or when the pain is felt. This is a most difficult complaint to cure, and some great authorities say it is incurable, but we have evidence where perseverance and regular use of Levasco has effected the cure. No athlete should be without a bottle of Levasco. A little rubbed on the limbs previous to and after any extra exertion ensures your fitness for the next event. Headache Cured in a few minutes. Earache Cured in 2 minutes. Toothache Cured in 2 minutes. Great care should be taken that Levasco is not applied to wounds, cuts, or embrasures (sic). A Is. ld. bcttle was found to hold rather less than 1 fluid ounce. Analysis eh owed the presence of oleo-resin of capsicum, oils of rosemary and lavender, camphor, alcohol, and what appeared to be a trace of soap. The quantities of the different ingredients were determined as exactly as possible, and the results indicated the following formula, and a mixture prepared in accordance with it was practically indistinguishable from the original : Oleo-resin of capsicum 3 grains Camphor 6 ,, Oil of lavender 3 minims Oil of rosemary 4 ,, Soap grain Alcohol (90 per cent.) to 1 fluid ounce Estimated cost of ingredients, d. if methylated spirit were used; about 2Jd. if made with rectified spirit. DYXOL. This preparation is supplied by a firm in a small town near London. It is stated on the package that: Dyxol cures Neuralgia., Toothache, CoM in the Head, Headache, Stiff-neck, Lumbago, Rheumatism, etc., etc. Further particulars are given in a circular enclosed with the bottle, from which the following extracts are taken : This is a simple Preparation of great value for the removal of all kinds 12 of Pain* Most of theee are caused by Congestion of the Blood in certain of' the body. Relieve thia Congestion and you dnve away the ha 3 the power, above all other known preparations, of almost insttly dispersing congested blood. Ita efficacy in this direction can be easily demonstrated. Bub one drop of Dyxol on the face, when in leas than one minute, the spot will temporarily redden through the flow of blood to tie surface. In another advertisement the following statements occur: Simply rub on or inhale Dyxol according to directions, and neuralgia vanishes like magic. Muscular Rheumatism is epeedily relieved by rubbing in a little Dyxol. Dyxol quickly removes the most obstinate cold in the head and on the chest, and it is an excellent remedy for Headache, Toothache, and Earache. Dyxol inhaled prevents influenza. A Is. ld. bottle contained 2 fluid drachms. The general directions are : No rubbing is necessary. Apply one or two drops to the part affected. When using, fan away the vapour which arises. This will prevent dis- comfort to the eyes. To produce a milder action add a small quantity of Dyxol to an equal quantity of pure Olive OiL Analysis showed the principal constituent to be volatile oil of mustard, others being oils of pimento and nutmeg, liquid paraffin (heavy and light), and a fixed oil; the latter appeared to be cottonseed oil, but the quantity was too small for positive identification. The results of quantitative analysis indicated the following formula, and a mixture prepared in accordance with it was practically indistinguishable from the original : Essential oil of mustard .................. 20 per cent, by volume. Essential oil of nutmeg ..................... 20 Essential oil of pimento ..................... 4 Cottonseed oil ................................. 6 Liquid paraffin, yellow ..................... 17 ,, Kerosene ....................................... 33 Estimated cost of ingredients for oz., 2d. POND'S ARTHRITICUS. This preparation is supplied by a firm in London. It is stated on the label that it cures Gout, Rheumatism, Rheumatic Gout, Lumbago, Sciatica, and all Rheumatic Affections. ... It contains no drugs, no colchicum. Arthriticua neutralises all Gouty and Rheumatic Acidity in the Stomach, Liver and Bowels; removes the offending matter from the System, the Blood is purified, the Liver and Kidneys are relieved, the Joints become lupple, and there is a general freedom from pain. The Skin, participating IB the improvement, loaea any Gouty Eczma wnioh may exist, and MBumes a healthy appearance. 13 A pamphlet enclosed in the package bears the title: Gout and Goutiness. Their cause, treatment, cure, and prevention. By Geo. P. Pond, M.P.S., Surgeon- Chiropodist. In practice since 1857. The degree of enlightenment to be obtained from this treatise may be judged from the following extractor No food or drink is gouty; yet, no alcoholic drink can be said to be good for gout; that is, anti-gout; it is the quantity and quality which are so. ... No one can reasonably 6Vny an instinctive knowledge and a physical power exerted in the stomach by a conscious principle which selects and rejects, and which in its natural purity may be ranked as a nerve of sense. . . . Air, again, is as necessary with every mouthful in the process of digestion as the gastric juice itself ; it mixes with the saliva which pours out of four different glands of different kinds and forms a powerful solvent for the food. . . . Water, like air, is nourishing. . . . Cold is death, warmth is life. Cold is, perhaps, the greatest cause of disease. ... Of all supposed remedies to strengthen the body, cold baths in cold weather are the most dangerous. Several other preparations from the same maker are recom- mended in the pamphlet. The price of " Arthriticus " is 2s. 6d. per package; this was found to contain a bottle holding nearly 13 fluid ounces of liquid and 16 powders. The directions are: One of the Powders to be taken with every dose, mixed thus : In a tumbler pour a wineglassful of water, mix with it a sixteenth part of the Arthriticus, then add one of the Powders and drink immediately, while effervescing. It is ordered to be taken night and morning for gravel and affections of the kidneys and bladder, and all abnormal con- ditions of the' urine; twice or thrice daily for rheumatism, sciatica, lumbago, etc. ; and similarly in other cases. The powders varied in weight from 10.9 grains to 17.4 grains, the average being 14.2 grains; they consisted of tartaric acid. Analysis showed the mixture to have the following composition : In one dose, approximately. Lithium citrate 1.4 parts 5.0 grains Potassium citrate 0.9 part 3.0 Sodium citrate 0.2 0.7 grain Sodium salicylate 1.5 parts 5.3 grains Potassium bromide 1.6 ,, 5.6 Potassium bicarbonate 8.0 28.0 Glycerine 5.1 18.0 Chloroform water, about 10 ,, by measure Water, to 100 14 On mixing a doee of the liquid with one powder, the resulting draught would be alkaline even with the heaviest powder; the alkalinity would of course be greater when the lighter powders were used. Estimated cost of ingredients for mixture and powders, 2$d. MAGIC FOOT DRAFTS. This is the name by which plasters, to be applied to the soles of the feet for the cure of rheumatism, are supplied by the Magic Foot Draft Company, London, the price being 4s. 6d. per pair. In addition to the numerous advertisements of the article by name, others have appeared recently, offering in the name of R. A. Oliver to send "my Celebrated External Treatment [for Rheumatism] . . . to try free" to anyone sending his name and address. On sending a name and address a pair of the " Foot Drafts " was received (differing from those sold in the ordinary way by bearing no revenue stamp), together with a long letter and a printed sheet of testimonials. The letter states : the Drafts cannot be purchased for less than 4s. 6d. per pair anywhere, and you can see that we could not afford to send them on approval if they did not really cure. To introduce our great discovery most favourably to you, and through you to your friends, we are going to make this extraordinary inducement : Give this pair of Drafts a careful trial ; if the results give you faith in our wonderful absorption method, as they must, we shall be pleased to send you three more pairs of our Foot Drafts on receipt of 11s., and as we make no charge for the first pair to all those who accept this offer, this will make four pairs (18s. worth) of Magic Foot Drafts for only 11s. . . . We have found by careful study of this disease, based on years of experience, that this number of Drafts will effect a cure in nine out of ten patients, because it nearly always takes all the power of the first two pairs to open up the clogged pores and start the removal of all poisonous acid urates. It is the third and fourth pair that invariably bring that sense of relief and freedom from pain that every poor sufferer is looking for. This was followed at short intervals by other letters pressing for money to be sent. In the second it is stated : We take a sincere interest in your case [no case had been even mentioned in sending for the " cure "], and we are going to cure you. Now that the cure has been started, every day's delay makes it more difficult for the Drafts to do their work, and we trust that we shall hear from you by return post. 15 From the third letter : We prefer to think that the promise you made us two weeks ago has escaped your memory. [Of course no sort of promise had been made.] From the fourth : We think that we are justified in asking to hear from you, for we have spent some considerable time and money in your case ; frankly, because we were interested in it. . . According to our terms, which you accepted when writing for the first pair of Drafts, we must have by return either 4s. 6d. (for which another pair of drafts will be sent) or your state- ment on honour that you received no benefit. . . . We guarantee to cure you. The letters quoted freely from alleged testimonials, and further printed sheets of these were also sent. On one of these is printed in large capitals: " We guarantee Magic Foot Drafts to cure any case of rheumatism ! ' ' Curious discrepancies are shown by some of the testimonials. Thus in the advertisement, referred to above, in which the name " Foot Drafts" is carefully avoided, we read: A marvellous cure has been effected in the case of Mr. James Bodman, 8, The Mount, Frome. Mr. Bodman writes : "I have suffered from Rheumatism for the past seven years, and was almost a hopeless wreck. I tried all sorts of remedies and doctors, but to no avail, and was sinking fast when I tried your treatment. I am glad to say that it has cured all my sufferings, and I have had no aches or pains since. I may add that I am 72 years old, and feel as supple in my joints as a young man. The following is printed on one of the sheets mentioned above : 8, The Mount, Frome, The Magic Foot Draft Co., 1st Feb., /09. Shoe Lane, B.C. Dear Sir, I received your letter of recent date, and am pleased to give you the following account of my case of Rheumatism. I have suffered from this complaint for the past seven years, and was almost a hopeless wreck. I could neither dress nor undress without help. I could get no rest in bed or up, and my life was a perfect misery. I tried all sorts of remedies, too numerous to mention, which did not give me the least comfort. I also saw a doctor, who stated that he could not cure me. He, however, gave me something to relieve the pain for a couple of nights, but then I became even worse than before. At last I gave up all hopes of ever getting better ; in fact, I felt I was fast sinking, until a kind friend called to inquire after me. She said it grieved her to see me walk about such a pitiful sight, and asked if I would try Magic Foot Drafts, as she had received such good results from them. I consented, and she wrote to you for me. I only used three pairs, which cured me of all my sufferings, and I have had no achee or pains or any other complaint since. I may add that I am in my 72nd year, and feel as lissom in all my joints as a 16 yonng man. I cannot estimate the value of your Magic Foot Drafts *6 sufferers from Rheumatism. I have highly recommended them to several sufferers since my cure. I scarcely ever go out without someone asking me how I got so well. It makes me feel almost like an agent of the Magic Foot Draft Co. Please send me another of your books, so that I may bring your treatment more directly before my friends and acquaintances. Again thanking you, I remain, yours faithfully, JAMES BODMAN. Yet again, in one of the letters from the Magic Foot Draft Co., already quoted from, dated " June 2nd/ 10," it is stated that: Mr. James Bodman, of 8, The Mount, Frome, Somerset, has just written ns regarding the result of three pairs of Drafts. " I have suffered from Rheumatism for the past seven years, and was almost a hopeless wreck, as I could not rest in bed nor when I was up, so that my life was a perfect misery. I tried various remedies, and also saw a doctor, who, while he could not cure me, gave me something to relieve the pain for a couple of nights, but I became worse after this. I had given up all hope when a friend who caPed to see me, stated that she had received wonderful results from Magic Foot Drafts, and asked for permission to send for a pair for me. I am now delighted to tell you that after wearing three pairs of Drafts, I have not an ache or pain, and I am completely cured of ah my sufferings. I am in my 72nd year, and I feel as supple now in all my joints as a young man. I cannot estimate the value of your Magic Foot Drafts, and I can never thank you enough for the benefit they have given me." This had been " just received " on June 2nd, 1910. The phraseology has not changed much in the interval of sixteen months ; but as the gentleman is still in his 72nd year, evi- dently time stands still with him ; curiously, though, in the letter first quoted, which appeared in a newspaper advertise- ment on May 18th, 1910, he is already 72 years old. One wonders how Mr. Bodman was induced to send three variants of his letter, one of them obligingly omitting any reference to Foot Drafts by name and substituting ' ' your treat- ment. ' ' The same differences are shown in other letters ; in one place is a letter over the name of J. W. Ludell, ascribing two cures to Magic Foot Drafte, while in the advertisement in which the latter name is not used he is represented as saying that one cure was due to " your Antiseptic Plasters " and the other to "your treatment"; two variants are given in different places of a letter from Mr. J. Bull, in one of which he says: " I am thankful to think I tried the Foot Drafte, for they are worth double what you charge for them," and in the other: " I am thankful that I tried your Foot Drafte, for they are worth a good many times th money that I paid." All thie appears to 17 suggest either that the writers of the testimonials are very obliging in supplying varying readings of them, or else that the advertiser alters them according to his fancy j unless indeed, they are entirely manufactured. A booklet which is also sent, entitled " Rheumatism, Its Cause and Cure," contains various plain and coloured pictures professing to represent nerves, arteries, etc., of the leg and foot, and gives an account of how the " Drafts " are supposed to act; the following extract will suffice: The rheumatic sufferer faces this situation : His or her system has become more or less clogged with rheumatic poisons lithic acid, uric acid, lactic acid, or any other toxin, as the case may be. This poison may be either driven out or drawn out. Certain agents salicylic acid, for example will sometimes accomplish the former result ; but the system will then contain a poison worse than the rheumatism. In fact, remedies which are strong enough to be effective against rheumatism almost in- variably ruin the digestive organs. Magic Foot Drafts, as the name implies, draws the poisons out through the pores of the tender skin on the bottom of the feet. The Drafts absorb this poison. A pair should be worn only sdx days, as they become filled with the waste matter from the body and need renewing in that length of time, if the case is a bad one. . . . Physicians are already using them in their regular practice, and recommending them. The " drafts " consisted of plasters spread on a sort of jaconet backing, of oblong shape and measuring about 5 in. by 3| in. ; the darker central portion measured about 3f in. by 2^ in. The margin was coated with about 10 grains of sticky material, which had the physical and chemical characters of " Venice turpentine " ; the darker portion, or the plaster itself, weighed about 80 grains, and was found to be a mixture of Stockholm tar and the powdered rhizome of white hellebore (Veratrum album); determination of their proportions showed the formula to be, approximately : Powdered white hellebore 40 per cent. Stockholm tar 60 No other ingredients could be detected. Estimated cost of ingredients for one pair d. CELMO, This preparation is supplied by the Celmo Company, London. It is in the form of tablets, of which a 2s. 9d. bottle contained 18 thirty-six. In a booklet contained in the package the tablets are described as : Specific for all uric acid ailments, viz. : Gout, Rheumatism, Rheumatic Gout, Lumbago, Gouty Dyspepsia, Sciatica, Eczema, Neuritis, Gouty Eczema, Suppressed Gout, etc. Other extracts are : In order to effect a cure the first requisite is to remove the cause. This can only be accomplished by administering a remedy which has the power of dissolving uric acid, and which will also restore the normal alkalinity of the blood so as to prevent fresh depositions. This remedy we present in " Celmo " Tablets. It is the One remedy that achieves a complete and permanent cure, and is the only medicine in the world that has a direct and combined action on the Kidneys, Liver, Stomach, Bladder, Bowels, and Digestive Organs. . . . We find, in the large majority of casee, from five to eight bottles, 4s. 6d. size, sufficient. The tablets must be taken with absolute regularity, and there should be no interval whatever between the bottles. It is always advisable to state your ailment and order of us direct. We then can change the dose as and when required to expedite a cure. A eo-called " analysis " is published, which is as follows: I have made a careful Chemical examination of the above-described sample of Compressed Tablets known as " Celmo," and from my results I am able to certify that they are absolutely free from Arsenic, Mercury, Opium, Digitalis, and Colchicum. I find that these tablets have been prepared from pure drugs of the best possible quality, and contain nothing of an injurious nature whatsoever. The formula from which they are made has been submitted to me, and I am of opinion that it is an excellent one in every way, and one which is not capable of improvement. After reading in the booklet quoted from that Celmo ie "the One remedy," and " the only medicine in the world that," etc., it is somewhat surprising to read, in another circular also enclosed in the package, that: Every intelligent person is aware it is impossible to prepare any one medicine for Rheumatism, Gout, etc., to suit every system. We over- come this difficulty by supplying "Celmo" Tablets in two forms, both for Uric Acid ailments. It further appears that there is also a " Celmo No. 2 " for indigestion, etc. (described in Chapter V.), "Celmo Laxa- tive," " Celmo Ointment," and " Celmo Liniment." 19 The directions are: In commencing treatment, take two tablets with half an ordinary glass of water just before or after each of the three meals, making six tablets per day. In very severe cases three tablets can be taken at a dose until pain is relieved, then two as above. A child's dose, one-half to one tablet at times stated. The tablets had an average weight of 5 grains. They had a slight smell of oil of juniper, but the amount present was far too small to be determined, and can only be described as a trace. Analysis showed the presence of acetyl-salicylic acid (commonly known as aspirin), powdered charcoal, maltose, glucose, and dextrin (these three being evidently present as malt extract, used for binding the powders together), magne- sium silicate, alkaloid, extractive, and the mineral constituents commonly found in vegetable extracts ; a slight trace of a pun- gent substance resembling capsicum oleo-resin was also present. Ordinary talc is magnesium silicate, but the mineral of that composition here present did not have the physical properties of ordinary talc ; it is, of course, quite inert, talc being com- monly added to tablets as a lubricant to facilitate their produc- tion by a machine. The alkaloid and extractive did not show any characters by which they could be certainly identified; the alkaloid did not agree, in its behaviour to various tests, with any of the alkaloids in ordinary medicinal use. The proportions of the various constituents were determined as accurately as practicable, and indicated the following for- mula : Acetyl-salicylic acid 35.5 per cent. Powdered charcoal, about 8.0 Malt extract, dry 18.0 Magnesium silicate 14.5 Other mineral constituents 2.8 Water 12.3 Alkaloid 0.5 Extractive, about 8.0 Oleo-resin of capsicum trace. Oil of juniper ,, DR. BENGUE'S BALSAM. This preparation, made by a firm giving addresses in Paris and London, differs from most of those dealt with here in the important respect that the principal constituents are stated on B 2 20 the label, and it , therefore, not altogether a " secret remedy." It is included in this series, since it is advertised to the publi "A wonderful Remedy for Rheumatism, Gout, Neuralgia." In a circular enclosed in the package it is stated that: The following is an enumeration of the different diseases in which Dr. Bengue's Balsam has proved to be the most effective scientific remedy. Acute or Chronic Rheumatism ; Spread the Balsam on the affected part and cover up carefully with cotton wool. After two or three applications the parts affected should be cleansed with warm water so as to facilitate the absorp- tion of the Balsam when the next dressing of the Balsam is applied. Gout; Various forms of Neuralgia, Facial, Intercostal, Lumbar Ovarian, Sciatical; Locomotor Ataxy; Various forms of Hyperaesthesia ; Saturnine Colics; Nephritic Colics; Peritonitis Gastralgia ; Torticollis; Zona, The "Balsam" is supplied in collapsible tubes j a 2s. package contained 11 oz. On the label, following the name, are the words " Menthol, Methyl^Salicylate, Lanolin/' and these three substances were found to be present. Analysis showed the composition to be: Menthol ISpercent. Methyl salicylate 20 Lanoline, anhydrous 54 ,, A fat, apparently lard 8 ,, Estimated cost of ingredients, l^d. BOX'S PILLS AND GOLDEN FIRE. These preparations are supplied from an address in a south coast town. The " Golden Fire " is more especially recom- mended for rheumatism, but it is stated that " in severe cas?s of Rheumatism, etc., Box's Pills should be taken in conjunc- tion with the ' Golden Fire,' " and the two are associated In many of the statements made. The following specimen ex- tracts are from circulars enclosed in the packages, and other advertisements : Box's Golden Fire is a New Discovery for the removal of diseases, being an Electric Fluid of Intense Power in rapidly attenuating, dissolving, and removing obstructions in any part of the system. Box's Golden Fire, which is used internally and externally, is a subtle extract from the vegetable kingdom, the hidden fire or life of plants and flowers, the " Quint-essence of Life ! " Call it, if you please, " Bottled Fire ! " " Bottled Health ! " " Bottled Life ! " 21 This Great Remedy and its accompaniment are sure cures for rheu- matism, diphtheria, etc. In some advertisements the medicines are described as " The Giant Remedy," and it is explained that The Giants have declared war against unbelief, and are determined to push the battle to the gate. The Giants ask for no quarter nor will they show any, therefore one of the contending parties must be wiped out. The Giants in fight are a noble race and are of ancient origin. Their fathera lived in Eden, and their seed, rising upon the wings of the wind, ulti- mately spread over the whole earth. They have lived since the days of creation in the fields, without a covering, sipping the dew and drinking in the sunshine and the rain. When in their prime they were translated to where they sleep. And when the proprietor of the Giant Remedy calls them they awake, and, springing upon the foe, they quickly overwhelm and annihilate him, and joyfully hand back the captive to his friends in perfect health. Their origin is Divine. As you now see them so they came from the hands of their Creator, filled with the nectar of health and life from root to leaf. In a circular dealing more especially with the pills directions are given for their use for costiveness, bad taste in the mouth, heart disease, corpulency, sick headache, wind 'and swelling after meals, toothache, influenza, inflammation of brain, stomach, bowels, lungs, kidneys, etc., fevers, sore throats, diphtheria, and tumours. One of the "testimonials" is headed, in large letters, "-Cancer Cured." The full direc- tions in the case of influenza will serve as a sample: Take as directed on the label. Also make a strong tea of Elder Blossom and Peppermint Herb, and drink a pint at bedtime. Repeat the tea at bedtime for two or three nights, if necessary. It seldom requires repeat- ing. This will save when on the brink of death. The thrilling nature of some of the testimonials may i>e judged by an extract: My brother-in-law had his leg jammed in South Africa between rocks, just above the ankle. He came home, and feared he would be a cripple for life. I advised him to get your Pills and "Golden Fire," which he did, and after 6 days a spot came out under the heel as Black As Your Hat. He has since left for America Quite Cured. Another circular states : As certain medical men have done their best by tongue and pen to persuade the public that Box's Golden Fire is poisonous, the said Golden Fire in consequence has 'been submitted to a rigid Chemical Analysis. Tfie following Report from the Eminent Analyst will effectually sew up the lying lips. 22 Then follows the report, which is in the usual style of such " analyses," and states that the " Golden Fire " was found to consist of "certain carefully selected and powerful, but per- fectly innocent, ingredients, which combined (as in the mix- ture) may be taken internally or applied externally without fear or hesitation." The circular continues: Those who raise the cry of " Poison " are wholesale traffickers in the same it is their stock-in-trade : Poisons bring grist to their mills, while the poor victims who swallow them perish by thousands. The directions for use are : For Rheumatism, Lumbago, Gout, Neuralgia, Sprains, Chest Affections, Asthma, Bronchitis, Swellings, Tumours, Enlarged Joints, etc., the Golden Fire should be rubbed in briskly three or four times a day; and in extreme cases a piece of flannel should be saturated with the Golden Fire and applied after each application. For Sore Throat, Quinsy, and Diphtheria, rub in several times a day; and to one tablespoonful of Golden Fire add one tablespoonful of water and gargle every two hours. For the above, Golden Fire should be taken internally three times a day, in a little water, beginning with six drops and increasing a few drops each dose until a teaspoonf ul is reached, and continue until well. For toothache, apply Golden Fire to the Tooth and rub it well into the gums. For Neuralgia, Bruises, Sprains, etc., rub it briskly over the seat of pain. For Polypus, apply with a camel-hair brush, and rub in on the outside twice a day. A Is. l|d. bottle of the "Golden Fire" contained nearly 2 fluid ounces of liquid. Analysis showed this to contain acetic acid, sodium chloride, volatile oils, a little alcohol, starch, dextrin, extractive, and the pungent principle of cap- sicum. The mixture of essential oils appeared to consist of oils of camphor, eucalyptus, rosemary, and amber. After determining the quantities of the other ingredients, the amount left to be described as starch, dextrin, and extractive was about 7 per cent, of the liquid; this part possessed no characters by which its source could be determined, but the liquid contained solid particles which appeared to be due to defective straining, and microscopical examination of these showed them unmistak- ably to consist of barley, lobelia, and capsicum, and the liquil appears, therefore, to be a decoction of these, with the addition of the other ingredients named. The pungency was just similar to that of an aqueous decoction of capsicum ; the pro- portions of barley and lobelia could not be determined; the 23 amounts of the other substances found are given in the follow- ing formula : Oil of amber 0.16 per cent. Oil of rosemary 0.16 Oil of eucalyptus 0.32 Oil of camphor (essential) 1.3 Sodium chloride 6.4 Glacial acetic acid 6.4 Alcohol 1.0 Decoction of capsicum. Decoction of barley. Decoction of lobelia. It is hardly necessary to point out that lobelia is a dangerous drug to be administered and taken by ignorant people. A Is. Ifd. box of the pills contained fifty-three of various sizes and shapes, roughly coated with talc, and having an aver- age weight of 2i grains each. The directions on the label are, " Dose Two pills morning and evening, after meals." Analysis showed the presence of powdered capsicum in considerable quan- tity, this drug forming, in fact, so large a proportion of the pill, that the recognition of other ingredients was a difficult matter ; microscopic examination showed also powdered gentian, and a flour which did not agree perfectly in character with any ordinary flour, though having a considerable resemblance to barley flour ; small quantities of soap and aloes appeared to be present, and a trace of an essential oil or other aromatic substance which was not identified. The following formula gave a pill substantially agreeing in characters with the pill under examination : Powdered capricum 35 parts. Powdered gentian 15 Flour 15 Aloee 20 Soap 5 Water to 100 BOWDEN'S INDIAN BALM. This article is supplied by a firm in the West of England at prices from 7|d. to 10s. A tin priced 2s. 9d. was found to contain about 4 oz. It is described on the package as For all Inflammations, M'uscular Complaints, Skin Diseases, etc., as Inflamed Eyes, Neuralgia, Face-ache, Bronchitis, Rheumatism, Eczema, Ringworm, Cuts, Stings, Wounds, Scalds, Burns, Strains, Piles, Chil- blains, Chaps, etc. Circulars enclosed in the package also contained recommenda- tions of the use of the Balm for colds, congested nostrils, catarrh, whooping-cough and croup, lumbago, stiff-neck, erysi pelas, bedsores, irritation after fever or vaccination, eruption, abscesses, boils, ulcers, itching at the anus, sores, sprains, bruises, mumps, abrasions, stings of mosquitos and other in- sects, sunburn, sore and tender feet, inflammation of the bowels, cancerous sores, asthma, coughs and chest complaints, sore throats, whitlow, corns and warts. It is further stated that : This Preparation contains no less than seventeen ingredients, including Valuable Balsams, Extracts, Essences, Indian Oils, etc., and so is a veritable little Medicine Chest in itself. Few other remedies will be required where it is kept at hand and used habitually. The most delicate Lady or Child, as well as the strongest Athlete, will find the Indian Balm to be a treasure. It can be used with perfect safety upon an open wound, be placed upon the Eyeball for Inflammation, or be used internally for Complaints of Throat and Chest. It will draw out every particle of injurious matter before healing any Ulcer or Sore, thus preventing a return of the trouble. Prompt application to Wound, Scald, or Burn is the best preventive of Blood Poisoning. Lengthy directions are given for ite use in a variety of cases ; the following will suffice as examples : Ophthalmia and Inflammation of the Eye. Eub the Indian Balm round the Eyes two or three times a day. In acute cases apply inside the lids. Inflammation of the Gums, Toothache, and Faceacbe. Well rub the Balm on the Gums and Face. When the Tooth is hollow the Balm can be inserted on cotton wadding. Inflammation of the Bowels and Pain in the Small of the Back. Foment the parts with hot water, and briskly rub with Balm (10 to 15 minutes at a time) till relieved. It would appear to be equally efficacious when administered internally, for we read : Sufferers from Asthma, Croup, Bronchitis, and all Throat or Chest Complaints find the soothing and healing effects of Indian Balm, when taken internally on lump sugar, to be immediate and remarkable. It also enables patients to get rid of injurious phlegm. Public Speakers and o efation ""* '*" ^ E&lm P 1 ** 8 *" 1 to * and effectual in The " Balm " consisted of a brownish-yellow ointment Analysis showed the presence of about 7 per cent, of volatile oil, in which oil of eucalyptus predominated, and a fatty basis. The oil did not contain as much cineol as an ordinary good specimen of eucalyptus oil, and some evidence was obtained of 25 the presence of essential oil of camphor, terebene, and oil of lemon. The solid basis contained, besides fatty constituents, a very small amount of ammonia, and a little of a resinous substance ; the latter was not ordinary resin, but showed no distinctive characters sufficing for its identification. It may have been derived from balsam of Peru, or some similar ingre- dient, but comparison of its properties pointed to the proba- bility of a mixture of balsamic substances. The statement that seventeen ingredients are present may be true, for the essen- tial ingredients are a fatty basis, a mixture of volatile oils, and resinous material, and each one of these can easily be made of an almost unlimited number of ingredients mixed together ; no other active substance was found. An ointment prepared from the following formula, which is based on the analytical results obtained with the " balm," strongly resembled the latter, and only differed from it in minor points : Lard 35 per cent. Cocoanut oil 35 Tallow 10 Rape oil 5 Lanoline, anhydrous 4.5 ,, Balsam of Peru 1 ,, Oil of eucalyptus 5 Terebene 1.5 Essential oil of camphor 1.5 Essential oil of lemon 0.5 Solution of ammonia 1 ,, Annatto colouring a sufficiency. BATH SALTS FOR RHEUMATISM. Recently certain " bath salts " have been largely advertised for the treatment of complaints of this kind by means of baths. We give here the results of analysis of some of the principal articles of this kind. OZONIA. This is supplied by a firm in Dublin, in a packet, price Is., containing about 13 oz. The package contained a descriptive leaflet, from which the following extracts are taken : The introduction of Ozonia marks a new era in the treatment of Rheu- matism, Gout, and allied complaints. This remarkable preparation is used in the bathing water, where it reaches the source of the trouble through 26 the pores of the skin. The whole body is treated at once, and not the least trouble is entailed to the sufferer. The system is thoroughly cleansed the poisonous uric acid is neutralised, and the patient is reinvigorated. The method is new, tut it has hundreds of wonderful cures to its credit already so try one packet, and judge by results. . . The Bath Cure. Bathe in it that's all. There are many complaints which are acknowledged to have one root cause. The cause of Rheumatism, Sciatica, Lunabago, and Gout is the presence of too much uric acid in the Wood. The problem oi how to remove this poison has hitherto proved unsolvable, but now Ozonia has been proved to be the proper means. The worst cases of uric acid 'troubles yield to the soothing medicated -waters of Ozonia. . . . " Ozone," the health-giving principle of Fresh Sea Breezes, is liberated in the "Ozonia" 'bath, and has a marvellous exhilarating effect on the patient; this, combined with the stimulating effect of the other constituents of the bath, induces a feeling of bodily well-being which is most gratifying. How to use " Ozonia." Dissolve one packet m an ordinary bath of hot water, and immerse the body in it, keeping the face and back of the neck sponged. Remain in the bath at least 15 or 20 minutes, even longer if desired. The best time for taking the Bath is before going to 'bed, but this is not imperative. Number of Baths to be taken. In severe cases a bath every second night is advised, but when the acute symptoms have disappeared, a bath once or twice a week is sufficient ; in most cases, a series of 12 baths will be found to effect a perfect cure. If -total immersion is not feasible, stuping with a hot solution (a table- spoonful of " Ozonia '" to a gallon of water) is very beneficial, but com- plete immersion gives best results. Analysis showed the composition of the salt to be : Sodium carbonate, reckoned as anhydrous 77.00 per cent. Water 22-30 per cent. Chloride, reckoned as sodium chloride 0.46 per cent. Potassium salt a trace. In view of the statement, quoted above, that ozone is libe- rated in the bath, special search was made for any ingredient, such as percarbonate, perborate, or peroxide, which could yield oxygen, but no trace was found of any such substance. Com- mercial sodium carbonate commonly contains a little chloride, such as the quantity found. ANTURIC BATH SALTS. This preparation is supplied by a limited company in London. A tin, price Is. 6d., contained about 4J oz. It is described on the package as : For Gout, Rheumatism, Sciatica. 27 Directions. Dissolve the contemn ol one tin in a bath full of hot water. Take two baths weekly for six weeks. The water should be as hot as can be comfortably borne. In severe cases the contents of two tins may be used for one bath. If it is inconvenient to use a full bath, or for local affections fomenta- tions may be used ; for this purpose dissolve a tablespoonful of the Anturic Salts in a gallon of hot water, and bathe the part affected. After the cure an occasional bath is desirable. Analysis showed the salt to consist of : Sodium carbonate, reckoned as anhydrous 96.86 per cent. Water 2.70 C hlor id e trace Potassium salt ,, Perfume EHEUMSOL BATH SALTS. This is supplied from an address near London. A tin, price Is., contained about 5 oz. It ?'s described on the tin as : Uric Acid Solvent. For Rheumatism, Gout, etc. Directions for use. Add the contents of this tin to a full-sized bath of hot water. For a smaller bath less in proportion. A bath should be taken every third night for a month. Analysis showed the salt to consist of : Sodium carbonate, reckoned as anhydrous ... 87.96 per cent. Water 11.18 Chloride considerable trace Potassium salt trace Exsiccated sodium carbonate (B.P.) is practically anhydrous, and is priced in a wholesale druggist's list at 7d. per Ib. One pound of anhydrous sodium carbonate of commercial quality represents about 2| Ib. of common washing soda crystals. SOME GERMAN NOSTRUMS. Dr. F. Zernik, of Berlin, has continued the publication in the Deutsche Medicinische Wochenschrift of the results of his examination of various German nostrums. The following notes refer to preparations advertised for rheumatism. Dr. liichter's Orudon Essence preparation has been introduced at the " Hof-Apotheke " (a pharmacy holding the right of using the affix " Court ") in Elbing as a remedy for rheumatic and analogous affections. 28 The directions for use are that the essence should be taken m doses of from 4 to 6 teaspoonfuls according to the severity of the case, diluted in a tumblerful of sugar water. It is claimed that it contains a new chemical substance namely, ammonium iodatum salicyl. solubl. as well as other ingredients which the medical profession has found to be most useful during the past decades. Among these is mentioned " diaethyl- diamin," aromatic extract and brandy (cognac). It is sold in bottles, con- taining 135 c.cm., at 6s. the bottle. The fluid, which is dark brown and bitter, was found to contain ammonium salicylate and iodide, but not a trace of the "new " chemical substance, which Zernik points out has long been recognised in chemistry, piperazin, which is diaethylen-diamin and not diaethyl-diamin, as well as alcohol and some extractives and per- fumes, the nature of which could not be identified. Orudon Salt is sup- posed to act well in the same conditions as the essence. A bottle of this powder costs 5s. 6d., and is stated by the manufacturers to contain basic citrate of urea (an imaginary chemical substance !), magnesium, sodium, lithium carbonate, citric acid, sodium sulphate, and extract of almonds. The analysis proved it to be a mixture of about 10 per cent, tkeobromine- sodio-salicylate, 10 per cent, sodium sulphate, 4 per cent, urea, 16 per cent, magnesium citrate, 4 per cent, sodium citrate, 2 per cent, lithium citrate, and fully 40 per cent, oiteic acid, together with a bitter extract. No trace of a substance which could correspond to the alleged basic citrate of urea was found. /. Vollner's World-renowned Rheumatism Cotton-wool is, it is stated, manufactured by W. Vollner, Hamburg, London, and New York. It is claimed by the manufacturers that it produces five times as much warmth as ordinary cotton-wool, being impregnated with the finest kinds of resins. The packet costs Is. and contains 86 grams of a cotton-wool sheet, measuring 1 cm. in thickness, 36 cm. in width, and 80 cm. in length. On analysis Zernik found that the cotton-wool was ordinary raw cotton- wool, which had been superficially singed on one side and which was not even fat-freed. There was nothing else in the wonderful rheumatic wool. Limosan is vaunted as a certain cure for rheumatism, gout, and " stone." In one of the booklets accompanying the preparation testi- monials galore were reproduced. It consists of white limosan tablets and greyish-green laxative tablets; 30 of the former tablets contained in a tube cost 6s., while 15 of the latter cost 6d. Several tubes are re- quired for a course, since the patient is told to take 10 of the white and 4 or 5 of the laxative tablets daily. The composition is given as follows : Aethylenimin, 1 gram; glycocol-para-phenyledin (basic), 4.5 grams; lithium carbonate, 0.1 gram; salicylic salt, 1 gram; and acetic salt, 0.4 gram. The first-named ingredient is merely a synonym for piperazin' the second name on the list is used instead of phenocoll, while the salicylic salb has the same form as the substance usually known as salocoll. The laxative tablets are stated to contain Tinavelly senna, rhamnus purshianus, and frangula, of each 20 parts; liquorice root, rhizoma root, Df each 10 parts; peppermint, marigold, and poplar tree leaf of each 5 parts. The action, therefore, would depend on the senna cascara sagrada, and frangula. The manufacturers have, it is stated, repeatedly been punished in courts of law for the puffing nature of the advertise- ments of these limosan preparations. Professor Tissander's cure for rheumatism, gout, and sciatica is stated by Zernik to be sent for 4. 6d. by " The Sabalek Syndicate," of London. Quoting from a letter received from this firm, the " cure " is said to be composed of a number of reagents which act against uric acid. These reagents, together with a kidney stimulant and a blood purifier, are com- bined by " Professor " Tissander in a very concentrated form. It is pleasant to take, and does not produce any deleterious effects of any kind. The examination revealed that the tablets contained sulphur, salts (chiefly alkali phosphates), and an emodin-containing vegetable powder (rhubarb, senna). Zernik concludes by saying : " This composition indi- cates sufficiently in how far the preparation can possess the action ascribed to it." CHAPTEE II. PBEPABATIONS FOB ECZEMA AND OTHEB SKIN AFFECTIONS. A selection from the numerous proprietary articles adver- tised for the cure of skin diseases, including ointments, lotions, dusting powders, and medicines to be taken in- ternally, is described in this chapter. It will be seen from the extracts from advertisements which are given that the claims made for the respective preparations are to a large extent contradictory and mutually destructive, as, for ex- ample, " sulpholine lotion is the only external skin remedy," '' eczema and all skin ailments are completely cured by sul- pholine lotion," and, on the other hand, " the potent ingre- dients of a remedy, which are necessary to the successful cure of eczema, cannot be contained in the form of a liquid. Lotions, besides containing mercury, must necessarily con- tain some alcohol or water, which are irritants and should be rigidly avoided." (The apparent implication that all lotions contain mercury is novel and surprising.) It is not always even necessary to take statements 'from rival makers in order to find contradictions ; statements made by one firm in different parts of their advertisements are sometimes quite inconsistent, as in the case described below where on one page it is stated that ' ' there is not one among the many healing extracts used which is not highly lauded by skin specialists the world over," and on the next page of the same pamphlet ' ' several of the medicaments used in the oint- ments and blood tablets are very rare and not in use in Great Britain, and do not form any part of the British doctor's 31 medical outfit." One of the commonest inconsistencies, of course, is that between the extravagant prospects of speedy cure held out to attract in the first place, and the far more guarded statements made when the patient has paid for the article and is beginning to find out for himself what its curative powers amount to. The first preparation men- tioned below furnishes an example of this ; in a Press adver- tisement readers are assured that "just a drop or two of D.D.D., the Guaranteed cure for Eczema and all Skin Diseases, applied to the burning skin, and that torturing, endless, nerve-racking itching is at an end " ; not only does D.D.D. stop all irritation and pain immediately we guarantee it but the cures that invariably follow are per- manent," while in a pamphlet supplied with this very article it is stated that ' ' the person fortunate enough to become familiar with D.D.D. Prescription in the early stages of his disease may commit the error of being impatient of cure. . The eruption may have appeared only on a few spots of his body, but this is evidence that the disease germ is lodged in his skin. The germs will grow and multiply and spread ; ... it may take some time to dislodge the germs from his skin. . . . Is it not worth careful study , a few months' patience, to be rid of that horrible malady? " A limited company, which uses the name of "Dr. Cas- sell," sends a list of questions to be answered and endeavours to persuade sufferers that it deals with them just as a quali- fied practitioner would do: "When you consult a doctor, he first inquires into the causes leading up to your trouble, then carefully examines all the symptoms and indications. Upon the results he forms his diagnosis, which in turn suggests the treatment. We do exactly the same when you return the examination form filled up." The trifling omis- sions of the years of study, training, and experience requisite for a medical qualification, and of personal examination of the patient, are treated as of no consequence; naturally, some illuminating diagnoses may be looked for under such 32 circumstances, as in the case described, where having re- ceived the answer " Eczema " to .the question " What are you suffering from? " and after " carefully studying " the answers to this and other questions, the company gravely informs the patient " You are suffering from a severe and disagreeable form of eczema." D.D.D. The preparation sold under this name is supplied by a firm in London at 2s. 3d. and 4s. 6d. per bottle; a 2s. 3d. bottle was found to contain 2.1 fluid ounces. A Press advertisement is headed : Peoriasis, Dry and Wet ECZEMA, and all skin diseases cured by D.D.D., the new liquid remedy, which gives instant relief, and a positive cure when everything else has failed. and the following claims are made: Just a drop or two of D.D.D. , the Guaranteed Cure for Eczema and all Skin Diseases, applied to the burning skin, and that torturing, endless, nerve-racking itching is at an end. . . . Not only does D.D.D. stop all irritation and pain immediately we guarantee it but the cures that invariably follow are permanent the disease never returns. The following are extracts from a pamphlet enclosed in the package, entitled " Cause and Cure of Skin Diseases " : D.D.D. is no ordinary patent medicine, but the prescription of the skin specialist, Dr. D. D. Dennis, who used the compound now known as D.D.D. successfully for years on all patients suffering with skin diseases. On urgent advice of his patients, Dr. Dennis was prevailed upon to have the compound put up as a proprietary article for sale through drug stores. In spite of the "guarantee" quoted above that D.D.D. stops all irritation and pain immediately, a caution is given against discouragement : Occasionally in bringing the disease to the surface, D.D.D. will spread the eruption temporarily over a much larger area. THIS is NOT A SIGN THAT THE MALADY IS GROWING MOKE SERIOUS, BUT ON THE CONTRAEY IT SHOWS THAT THE DISEASE IS BEING UPROOTED. It appears that more patience may be required, even when the sufferer is only " in the early stages," than the advertise- ment quoted might have led him to suppose: The person fortunate enough to become familiar with D.D.D. Prescrip- tion in the early stages of his disease may commit the error of being impatient of cure. . . . The eruption may have appeared only on a few spots of his body, but this is evidence that the disease germ is lodged in his skin. The germs will grow and multiply and spread ; ... it may take some time to dislodge the germs from his skin. . . . Is it not worth careful study, a few months' patience, to be rid of that horrible malady? " The germs " are, of course, freely utilized to give an air of scientific knowledge : The reader familiar with the deeper questions of medical science knows that there is still some dispute among the best authorities on the germ theories, but it is pretty we 1 ! understood now, largely as a result of Dr. Dennis's discoveries, that eczema is purely and simply a germ disease caused by germs that lodge in the skin. According to the germ theory, there must be several species of eczema germs, causing the several diseases known as eczema, psoriasis, ringworm, dandruff, etc. The germs are all of the same type, and produce ailments with varying symptoms, all eczematous. The germs live only in the skin, feeding on the oily ingredients of the epidermis. It might be interesting to know where " Dr. Dennis' dis- coveries " were published. D.D.D. is put up in two forme, called " D.D.D. Ordinary " and "D.D.D. Strong"; the "Ordinary" was taken for analysis. The directions for this are: The remedy may be applied in various ways ; it is best, however, to rub the skin as little as possible while making the application ; hence we recommend it to be applied by saturating a piece of absorbent cotton with D.D.D. and dabbing this gently on the parts affected, or applying it with a small camel hair brush, so that the pores will absorb the remedy. Analysis showed the liquid to be composed as follows : Salicylic acid 0.75 part Phenol 1.18 parts Methyl salicylate (oil of wintergreen) 1.00 part Glycerin 9.28 parts Alcohol 65.10 parts by measure Water, to 100 parts by measure It had a slight yellow colour, which may have been due to a trace of colouring matter, or may have been developed from the oil of wintergreen. The alcohol is by far the most costly ingredient, and the esti- mated cost of ingredients for 2.1 fluid ounces is 3|d. c 34 HOMOCEA. This preparation is made by a limited company in London. A Is. l$d. tin contained about f ounce, and a 2s. 9d. tin about 2 ounces. It is recommended for a very large number of disorders, as is shown by the following extracts from a circular enclosed in the package : Homocea . . . Ointmen/fe ... is far and away the best remedy known for Open Wounds, Sores, Cuts, Ulcers, Bad Legs, Burns, Scalds, Chaps, Wasp, Bee, and Insect Stings, Earache, Inflamed Spots, Skin or Flesh Troubles of all sorts, Broken Chilblains, etc. In treating any of the above lay Homocea lightly with the finger, or spread some on clean rags or lint and apply to the parts affected. For Bruises, Blotches, Chaps, Chilblains (unbroken), Eruptions, Swellings, Mumps, Croup, Sore Eyes, Bashes, Ringworm, Jelly Fish Stings, Sunburns, etc., etc., smear or gently rub in Homocea where required. For Piles (bleeding or blind) Homocea stands alone amongst remedies. It affords immediate relief at all times, and in many cases absolutely cures For Internal Piles the insertion of Homocea Suppositories is recom- mended. Cold in the Head is cured by putting Homocea up the nostrils and rubbing the bridge of the nose well with the Ointment at night. Soft Corns and Bunions are cured by applying Homocea as a pad, to be kept on day and night. Eczema (in many forms), Hay Fever, Prickly Heat Jigger, and Veldt Sores, Warts, etc., cured by Homocea. Homocea will cure the Bites and Stings of Mosquito, Gnats, Sand Flies, and, better still, will prevent these pests from attacking you, if the face, neck, hands, and other exposed parts of the body are smeared with the Ointment. It is impossible to bring within the compass of a short circular all that Homocea in its various forms will do, but we claim, without fear of contradiction, that there are few of the ordinary everyday ailments inci- dental to the human frame that Homocea, if promptly and properly applied, will not immediately alleviate and cure. The efficacy of Homocea is easily and unanswerably explained. It kills inflammation immediately it comes in contact with it, and you can readily understand why pain vanishes and wounds heal so quickly. Analysis showed the presence of eucalyptus oil in consider- able proportion, with beeswax, a soft fat, and a very small quantity of ammonia; evidence was also obtained of a small proportion of another essential oil, apparently oil of lemon, though, as essential oils are complex in composition, it is not possible to speak positively on this point. Other medicinal ingredients were found to be absent. The quantities of the 35 ingredients found were determined as accurately as possible, and the results gave the following formula : Oil of eucalyptus 25 per cent. Oil of lemon 0.2 Beeswax 25 ,, Fat 49 Solution of ammonia 0.8 The characters of the fat agreed with those of a mixture of lard and oocoanut oil in about equal parts. An ointment prepared according to this formula was practically indistin- guishable from the original. Estimated cost of ingredients for 2|- ounces (2s. 9d. tin), 2jd. ECZOLINE TREATMENT. This " treatment " is supplied by a firm at Swindon, and consists of ointment, tablets, and soap; the two former were taken for examination. An advertisement contains the following somewhat discon- nected expressions : A wonderful Remedy. Eczema, Rashes, Pimples, Spots, Sores, Ring- worm, Chaps, Chilblains, Rough Skin, Bad Legs. Stops all irritation at once. Cured by the Eczoline Treatment. Worth its weight in gold. Eczoline Ointment. A Is. l^d. box contained about 1 ounce. On the box it is described as A positive cure for Eczema, and good for all skin diseases. Analysis showed the presence of zinc oxide, sulphur (flowers), glycerin, a little water, and a fat which agreed well in its char- acters with lard, with a trace of oil of lemon ; no other consti- tuents were found. The quantities of the respective ingredients were determined, and the results gave the following formula: Flowers of sulphur 39 per cent. Zinc oxide 3.7 ,, Glycerin 13.5 ,, Lard 39.8 Water 4 Oil of lemon a trace Estimated cost of ingredients for 1 ounce, d. Eczoline Tablets. A Is. l|d. box contained 43 sugar-coated tablets, having an average weight, without the coating, of 5'2 grains each. These are described on the label as For Cooling, Purifying, and Strengthening the Blood. Dose One or two Tablets three times a day after meals. 36 Analysis showed the tablets, from which the coating 'had been removed to consist of Ferrous sulphate 16.5 per cent. Sulphur (precipitated) 56 ,, Talc 3 - 4 Starch 7.3 Extractive 16.8 The extractive was bitter, and showed the reactions of ex- tract of cascara sagrada, but it was not bitter enough or dark enough to consist only of this extract, and appeared to be a mixture of cascara sagrada, and an inert extract, the former constituting about 5 per cent, of the substance of the tablets. Taking the whole of the extract as being of the same price as extract of cascara sagrada, the estimated cost of the ingre- dients for 43 tablets is |d. DR. CASSELL'S MEDICINES. These are supplied by a limited company in a town in Lan- cashire. This firm is described on its notepaper as " Sole Agents for Great Britain, India, Africa, Australia, and all European Countries for Dr. Cassell's Specialities," and the " Specialities" appear to be really of American origin. The , form of advertisement which appears to be most in favour is a small announcement of An indispensable illustrated book written by an expert, dealing in a clear, common-sense way with a safe and speedy home cure of Skin Diseases of all kinds, with special chapters on Diseased Blood, Ulcers, Bad Legs, and " The Woman Beautiful," to be sent free on application. A request for a copy of this brought a pamphlet of 31 pages, together with a " self-exami- nation form," and a letter urging that the form should be filled up and returned. In a further circular the following statement is made with regard to the mode of procedure : When you consult a doctor he first inquires into the causes leading up to your trouble, then carefully examines all the symptoms and indications. Upon the results he forms his diagnosis, which in turn suggests the treat- ment. We do exactly the same when you return the examination form filled up : we carefully examine it, and from the answers you give to the questions we are able at once to select for you, from the numerous Ointments, Powders, Mixtures, and Medicated Tablets manufactured for this Company from the formulas of that world-famed specialist, Dr. Cassell, a treatment perfect in every detail with the requirements of your case. 37 It is further stated that: There is not one among the many healing extracts used which is not highly lauded by skin specialists the world over. Which seems rather inconsistent with the statement on the next page that: Several of the medicaments used in the Ointments and Blood Tablets are very rare and not in use in Great Britain, and do not form any part of the British doctors' medical outfit, yet are of such incalculable value as to constitute the basic strength and great healing virtue of the treat- ment. The "self-examination form" was as follows; the words in italics are the answers which were filled in : QUESTIONS. Date 19 Name in full Address in full Age. ST. Sex Male. Occupation. Groom-Gardener. Stout or thin? Medium. Married or single? Single. How long suffered? About two years. Are you able to work? Yes. If not, how long have you beero dis- abled. What are you suffering from? Eczema. What .was your previous health ? Good. Where are you affected? Arms worst; also neck and shoulders. What do doctors call your trouble? / don't know. Have you been treated for it ? Not by doctors. If so, how ? I have used some lotions. Have you attended any hospital? No. Is your general health good ? Yes. Are you constipated? No. Have you indigestion? No. Do you stand much? Yes. Are you in contact with much heat? No. Do you perspire freely? Yes. Are your hands much in soap and water ? No. Do you use muoh soda? No. Does your employment entail contact with gritty or irritating material, and if so, what? No. Have you much itching? Yea. Have you a scaly eruption? No. Is the part red or inflamed? Yes. Is there any discharge ? Sometimes. If so, what colour is it, and does it smell? Like water. Have you any bleeding from the part? No. Have you any pain? Yes. Is your trouble inclined to spread? Yes. Do you suffer from varicose veins? No. 38 Do little blisters form? No. Did the trouble start with a pimple? No. Have you any rash ? No. If so, where ? No. Have you a sore throat? No. Have you recently had measles or any fever? No. Have you ever suffered from any specific blood disease? No. If so, what? What is your usual diet? Porridge, bread and butter, coffee, meat and 'potatoes, beer, cheese. Do you eat much oatmeal, shellfish, or tinned food ? A good deal of oatmeal porridge. Are you a teetotaler? No, but very moderate. Are you worse more at one season than another ? No. What is your own opinion as to the cause ? I don't know. Here fill in any other details you may think of use. As the question, "What are you suffering from?" was an- swered by the word " eczema," it was not altogether surprising to be told in the letter which was received in reply : Your Examination Form has been duly received and carefully studied. You are suffering from a severe and disagreeable form of eczema. The letter proceeds with a warning that it is inadvisable to use ordinary salves, lotions, etc., indiscriminately, as you will readily realise that what will suit one person will not necessarily suit another, and many doctors don't appear to reconise [sic] the fact that the complaint should be treated both locally and constitutionally, therefore their treatment often proves ineffective. We make a special point of treating every case entirely upon its merits, and yours is one in which Dr. Cassell's combined treatment will produce speediest and most brilliant results. It appears, however, that even these ' ' speediest and most brilliant results" are not very speedy, as a further paragraph states : Although it may take a few months to effect a permanent cure, we are quite confident, if you make up your mind to have yourself properly treated now, it will save much suffering and expense in the future. The letter further intimated that the treatment would con- sist of a dusting powder, tablets to be taken internally, and an ointment, and that the charge would be 12s. 6d. As no reply was sent at once, this was followed about a week later with another letter, offering to send the medicines for 9s. 6d., and containing the statement: We are quite safe in guaranteeing a cure in your case provided you make up your mind to persevere for a reasonable length of time. 39 The sum required was then sent, and the articles named were received. The powder, in a pill-box, weighed a little lees than 1 ounce ; the bottle of tablets contained 90, of average weight 6 grains; and the pot of ointment contained just over 1 ounce. They were accompanied by an intimation that a further supply would cost 9s. 6d., and the following directions : Ointment. Wash the hands thoroughly clean in hot -water and apply a little of the Ointment to the affected parts every night on retiring. It is not necessary to use a great quantity, the chief thing being to have it evenly distributed on the parts requiring treatment. Powder. A small portion should be dusted on with a piece of clean lint every morning on arising. Tablets. One to be swallowed whole in water "three times daily, between meals. Cassell's Dusting Powder. This was labelled " Antiseptic Dusting Powder No. 2." Analysis showed it to contain boric acid, talc, maize starch, and powdered slippery elm bark. The proportions of the first two ingredients were determined and the other two estimated as accurately as possible, and the for- mula given below was obtained. A powder prepared in accord- ance with this formula agreed in all respects with the original, except that the latter had a faint perfume and a creamy tint; the traces of colouring matter and perfume were far too minute to be identified. Powdered talc 60 per cent. Powdered boric acid 20 Powdered maize starch 17 ,, Powdered slippery elm bark 3 Estimated cost of ingredients for 1 ounce, d. Cassell's Blood Cleansing Tablets. The label was marked " Price 4s. 6d. a bottle," and, as stated above, the bottle con- tained 90 tablets of about 6 grains each. Analysis showed the tablets to contain : Phenolphthalein 0.75 per cent. Potassium iodide 1.25 ,, Sugar 81 Talc, approximately 11 M Calcium carbonate and sulphate, approxi- mately 2 Water 1 ,, Extractive 3 The extractive showed no distinctive characters by which it could be identified : the tablets had a faint anise-like odourj 40 no alkaloid or other active principle was found. The dose of phenolphthalein in one tablet is 0.045 grain, the usual dose being 1 to 8 grains ; the dose of potassium iodide in one tablet is 0.075 grain, the official dose being 5 to 20 grains. If the extract present is taken as being of the same price as extract of taraxacum, the estimated cost of the ingredients for 90 tablets is |d. Cassett's Ointment. This was labelled "Ointment No. 2," and the pot contained just over 1 ounce. Analysis showed it to contain oils of wintergreen and eucalyptus, lanoline, a fat or oil, soft paraffin, boric acid, a small quantity of alkali, and a powdered vegetable tissue. The latter appeared to consist chiefly of a bark; it was carefully compared with a number of powdered drugs, but was not found to agree with any drug in ordinary use ; it showed a good deal of resemblance to powdered krameria root, and agreed exactly with it in the colour changes caused by various reagents, and while not identical with either of the species of krameria compared with it, the resemblance suggested that it might be from a nearly related plant. The proportions of the different constituents were determined as closely as possible, and the following formula was arrived at : Boric acid 8 per cent. Borax 2 Oil of eucalyptus 2 Oil of wintergreen 3 Anhydrous lanoline 4 Oil (? olive) 8 Soft paraffin 63 Powdered drug 7 Water 3 An ointment prepared in accordance with this formula, witi krameria root as the drug, closely resembled the original. SULPHOLINE LOTION. This lotion is prepared by a limited company in London. A Is. bottle contained 2 fluid ounces. This preparation is adver- tised in the following terms: Eczema and all skin ailments are completely cured by Sulpholine Lotion, which directly attacks all forms of Eczema, Eruptions, Pimples, Acne, Spots, Blackheads, or Disfiguring Rashes, leaving the skin in the soft, clear, supple, attractive condition designed by Nature. 41 And in a pamphlet enclosed in the package it is further stated that Sulpholine Lotion is the only external skin remedy. There is no phase of Eczema, chronic or acute, red, dry, scaly, or pustu- lar (moist), psoriasis, pityriasis, impetigo, prickly heat, tetter, salt-rheum, or even superficial scorbutic ulcerations, but Sulpholine will grapple with, and in most cases completely eradicate, leaving the skin its natural, clear, smooth, pliable surface. The directions on the label are: To be damped on with a handkerchief or piece of cotton wool, and allowed to dry. One application of the Lotion should be at bedtime. Analysis showed it to contain : Sulphur, precipitated 3 parts Zinc oxide 2.1 Calcium sulphate 0.6 part. Glycerin 9 parts. Strong rose water, to 100 parts by measure. The rose water is by far the most expensive ingredignt, and the estimated cost of ingredients for 2 fluid ounces is l|d. CADUM. Supplied by Omega, Limited. A Is. Ifd. tin contained just over 1 oz. This is described in a circular enclosed in the package as : The New Medical Discovery for the Treatment of Eczema, Psoriasis. Ringworm, Acne, Pimples, Blackheads, Itch, Facial Eruptions, Salt Rheum, Shingles, Herpes, Hives, Prickly Heat, Boils, Rash, Itching Piles, Cuts, Sores, Burns, Chafing, Sunburn, Scabies and other Skin Troubles. Its origin is thus described: The discovery of Cadum, the wonderful new skin remedy, was not the result of mere chance or accident, but of patient, painstaking investiga- tions, extending over a long period, by an eminent chemist who became pos- sessed of the conviction that the old method of taking internal remedies to cure external diseases was erroneous. After a careful study of all the best-known products, it was discovered that an extract from a particular part of a well-known treo possessed superior antiseptic and curative pro- perties, and exerted a powerful, beneficial effect on the skin tissues. It was, however, found that this valuable vegetable extract possessing such desirable qualities was difficult to compound with other ingredients neces- sary to present it in a form convenient to use. After further investigations and experiments, a method of special treatment was devised by which 42 this seemingly insurmountable difficulty was overcome, resulting in a unique combination of ingredients, possessing to a marked degree valuable therapeutic properties, the like of which has never before been produced. Directions are given for the use of this preparation in some thirty affections of the skin. Analysis showed the presence of zinc oxide, sulphur, boric and salicylic acids, oil of cade, and a paraffin basis. The pro- portions of the several ingredients were determined as accu- rately as possible; since oil of cade is variable in composition, and there is no direct means of determining its quantity in such a mixture, this was estimated from a number of comparisons with known mixtures, and the figure given is certainly not far from exact. The formula arrived at is : Zinc oxide 11.3 per cent. Flowers of sulphur 8.0 Boric Acid 3-1 Salicylic acid 0.8 Oilofcade 7 Hard paraffin 10 ,, Soft paraffin 60 Estimated cost of ingredients for 1 ounce, Jd. POSLAM. This is supplied by the Emergency Laboratories, New York. A 2s. 3d. tin contained ounce. It is described in a circular enclosed in the package as The Newest Medical Discovery for the treatment of Eczema and all other skin affections. Some further extracts from this circular are as follows : It is a singular fact that, notwithstanding the great strides that have been made in medicine for the past decade or two, skin diseases, and particularly eczema the worst of them are about as little understood by the medical profession to-day as they were a generation back. Eczema is one of the most prevalent diseases, and statistics shows that at least 50 per cent, of humanity have it in some form or other. It may be that physicians have failed to give this trouble the proper amount of study because, not being a fatal disease, they have considered it unim- portant enough to wilfully neglect its thorough diagnosis. Another reason may be that the advertised preparations for eczema have been so exploited as to convey wrong impressions about the disease, bmg ,t to causes most ridiculous, and harping on tha erroneous idea 43 that it is a blood troublej only curable by internal remedies. Doctors, in the absence of any recognised specific for the disease, have given either internal remedies or ordered the use of special soaps, both of which courses siiow that the average medical man is helpless to combat the growing trouble of skin diseases. . . . LOTIONS AND INEFFECTUAL " REMEDIES." The potent in- gredients of a remedy, which are necessary to the successful cure of eczema, cannot be contained in the form of a liquid. Lotions, besides con- taining mercury, must necessarily contain some alcohol or water, which are irritants and should be rigidly avoided. . . . There is no need of an extended course of treatment in the cure of eczema. If the remedy is the right one, its effects will be apparent im- mediately, and the progress of its work may be noted daily. POSLAM, THE CUBE. The success of Poslam in the cure of eczema and all kindred skin diseases, has been absolute since its first introduction to the public and the medical profession. It is entirely different from anything yet used, and as a remedial agent in skin diseases, may be said to be positively infallible in its action. Hitherto there has been a common base to all ointments and salves that were supposed to be " remedies " for eczema. Poslam has a base of its own, and contains no grease, poisons, mercury, or any other harmful constituent. The general directions are: Apply Poslam twice daily, night and morning, directly to the parts affected. Do not rub or irritate, but apply gently. Analysis showed the presence of zinc oxide, sulphur, starch, salicylic acid, oil of birch tar, oil of cade, lanoline, and soft paraffin. Since oil of birch tar and oil of cade are both very complex bodies of variable composition, it is not possible to determine exactly the quantities present in such a mixture ; it is even possible that some samples of oil of birch tar might possess the properties observed, without the presence of oil of cade, and the latter is given in the formula with this reserva- tion. The various ingredients were determined or estimated as exactly as possible, and the following formula was arrived at : Zinc oxide Flowers of sulphur Maize starch Salicylic acid Oil of cade 12 per sent. . . . 8 18 1 5 1.5 Oil of birch tar 8 Anhydrous lanoline Soft paraffin ... 255 . 25.5 , Estimated cost of ingredients of ounce, |d. CHAPTEK III. NERVE TONICS AND " ELIXIRS OF LIFE." A very large class of proprietary medicines consists of those advertised as nerve tonics and restoratives of lost vitality, and a number of these are described in the present chapter. Some of them are conspicuously advertised in the newspapers, and are sold through retailers in the ordinary way ; while in other cases the interest of those likely to become purchasers is usually aroused by a small advertise- ment with a bold headline to catch the eye such as " Lost Manhood Restored "in which a free book is offered, to be sent by post on application. The applicant is not only urged by the contents of the book which is sent to place himself at once under the advertiser's treatment, but this advice is further pressed on him by letters at intervals. Medicines of this kind are not usually sold through retailers, but only direct from the advertiser to the consumer. The latter is often supplied with a list of questions to be answered, and to judge from the examples described when he has answered them, and paid the one or two guineas demanded, he is likely to be told that his is a complicated case requiring additional treatment, for which, of course, further payment is to be made. In some cases references occur to ' ' our con- sulting physician," or "our specialist," etc. In regard to specialists of this anonymous kind, some facts elicited at a coroner's inquest, mentioned in chapter XIX., throw some light on the probable value of such references. Obviously, no real expert would consent to work under such conditions as those indicated ; but even if that difficulty could be got 45 over, no satisfactory diagnosis could be made in the manner pretended, and the paying of a fee for advice in such circum- stances is a very different thing from paying for the atten- tion and skill of an expert who really investigates his cases. In regard to the nerve tonics supplied through retailers, it will be seen that some of these consist of a few simple and commonplace drugs, the cost of which is almost negligible compared to the price charged. Others, which have only recently appeared on the market, appear to be based at least in regard to the wording of the advertisements on the orchitic fluid suggested by the late Dr. Brown- Sequard, and a good deal of play is made with a few terms having a scientific appearance, but serving as, for example, "the red corpuscles or phagocytes," and "a vital extract (CaHsNi) " only to display to anyone understanding them the ignorance of the advertiser. The last of the articles dealt with has been very extensively advertised as a " brain and nerve food " ; our advertisement shows that the daily dose of this preparation, costing ninepence, represents about a teaspoonful of beaten-up egg and a wineglassful of skim milk. PHOSFERINE. This widely-advertised preparation is supplied at Is. l^d. and 2s. 9d. by a limited company in London. A Is. l|d. bottle was found to contain 2 fluid drachms, and a 2s. 9d. bottle just over 1 fluid ounce. Phosferine is described in an advertisement as The Greatest of all Tonics. A Proven Remedy for Nervous Debility, Influenza, Indigestion, Sleeplessness, Exhaustion, Neuralgia, Maternity Weakness, Premature Decay, Mental Exhaustion, Loss of Appetite, Lassitude, Neuritis, Faintness, Brain Fag, Anaemia, Backache, Rheumatism, Headache, Hysteria, Sciatica, and disorders con- sequent upon a reduced state of the nervous system. 46 In a circular enclosed in the package it is stated that Phosferine is a potent strengthening medicine, withal gentle in its action and perfectly harmless ; being akin to gastric juice, it rests and restores the digestive organs and regulates the bowels to normal action. The public cannot be too strongly warned against the many purging medicines advertised for indigestion, etc., which are not only a fruitful source of piles, but injure the coating of the stomach and sap the very gastric juice Nature is straining herself to supply. Unlike other tonic medicines, Phosferine does not injure the teeth or upset the stomach and cause constipation ; on the contrary, it will be found beneficial in these conditions. Phosferine may be taken at all times with benefit ; there is no possible objection to its continued use either as an appetiser or a general strengthen- ing and nerve remedy. Somewhat varying directions are given as to the quantity to be taken for different ailments, the dose being stated as from five to ten drops, to be taken from twice to four times a day. Analysis showed the presence of alcohol, quinine, phosphoric acid, and a little sulphuric acid; a trace of sodium salt was found, but this was probably an accidental impurity in the phosphoric acid; no other ingredient could be detected. Ex- pressing the acids as the dilute acids of the British Pharma- copoeia, and the quinine as the ordinary official sulphate, the formula arrived at is Quinine sulphate 0.67 part Diluted sulphuric acid 2.5 parts by measure Diluted phosphoric acid 54.6 ,, Alcohol 8.1 Water, to 100 The estimated cost of the ingredients for 1 fluid ounce (2s. 9d. bottle) is |d. GUY'S TONIC. This is a liquid prepared by a London firm; a bottle priced Is. l|d. contained 6 fluid ounces. In a circular enclosed in the package it is stated that : Guy's Tonic is a rich Cordial prepared from Vegetable Tinctures and other curative agents found in the British Pharmacopoeia. . . . Guy's Tonic is not put forward as a Remedy for "all the ills to which flesh is heir," for no such thing as a "Cure-all" exists. It is, however, confi- dently recommended for the specific Ailments enumerated. . . . The use of Guy's Tonic will be attended with the happiest results in : 1. Disorders of the Digestive System : Dyspepsia. Heartburn, Loss of Appetite, Pain after Food, Flatulence or Wind, a sensation of Nausea 47 (Sickness), Furred or white-coated Tongue, unpleasant Breath, disagree- able Taste in the Mouth, Drowsiness after Eating, a feeling of weight or discomfort in the Chest, palpitation of the Heart, shortness of Breath, and Acidity of the Stomach. 2. Functional Derangements of the Liver : Sluggishness, Congestion, Constipation, Biliousness, Despondency, Dizziness, Sallowness of the Com- plexion, Blotches on the Skin, dull pains between the Shoulders, variable Appetite, Headache, disturbed Sleep, Lassitude, and Irritability. 3. Disorders of the Blood : Anaemia, Emaciation, Paleness, Weariness, and Disorders dependent upon a Vitiated or Impoverished condition of the Vital Fluid. 4. Nervous Maladies : Neuralgia, Nervousness, Hysteria, Giddiness, Alcoholism, disturbed Sleep, unpleasant Dreams, confused Thoughts, lack of Confidence, Loss of Memory, Depression, Melancholy, Exhaustion, Languor, and affections due to Malnutrition of the Brain and Spinal Cord. 5. General Diseases : Gout, Rheumatism, Rheumatic Gout, Lumbago, and Disorders characterised by Perverted Nutrition and Lack of Vital Force. 6. Convalescence from Acute Diseases: also in cases of recovery from Influenza, Fevers, Bronchitis, and other exhausting Diseases, and in General Debility and Prostration from whatever cause arising. The dose is stated on the label to be : For adults, one tablespoonful. Under 9 years, one dessertspoonful. Under 2 years, one teaspoonful. Analysis showed it to contain small quantities of hydro- chloric and phosphoric acids, alcohol, bitter and aromatic sub- stances and colouring matter, and a trace of chloroform. No alkaloid was present; the bitter and aromatic substances pre- sent in very small amount agreed well with those of the official compound infusion of gentian ; the behaviour of the colouring matter indicated that it was cochineal. The quantities of the two acids and the alcohol were determined, and the amounts of the other ingredients estimated by methods of comparison. The following formula gives an exactly similar mixture : Diluted hydrochloric acid 0.59 parts by measure Diluted phosphoric acid 0.52 ,, Alcohol 2.27 Compound infusion of gentian 40 ,, ., Chloroform water 50 ,, ,, Cochineal colouring a sufficiency Water, to 100 parts by measure The estimated cost of the ingredients of 6 fluid ounces is $d. VITAE ORE. The article sold under this name is supplied by a limited company in London, price 4s. 6d. per package. An offer to send a package, containing sufficient for one month, to be paid for only if benefit is received, is largely advertised. The advertisement usually includes an illustration of a man's head, said to represent " Prof. Theo. Noel," de- scribed as " the well-known geologist." The following are extracts from one of these advertisements : I discovered by accident the dried residue of the greatest curative spring in the world. It seemed worth while to try whether this, when redissolved, would have mineral spring virtues. The results astonished me and those who experienced them. The spring was a marvel far ex- ceeding anything that Homburg, Harrogate, Aix, Bath, or any other spa can show. Some untraceable element defying the chemist's analysis is it Radium? enters into the rock. Whatever the element may be, its effect can be distinctly felt when the drink made from this deposit, which I call Vitae Ore, or "life-rock," is taken as a beverage. Those who use it say that it gives a degree of buoyant, cheerful energy, which they never, perhaps, experienced before. Everyone knows a few people with health and vigour to spare the men whose breezy personality carries all before it, so that no one can resist them ; the women whose warm bloom and feminine grace capture all hearts. Well, Vitae Ore will give these things to ALL, if used as I will tell you how to use it. No artificial drug enters into it. No artificial drug can rival its effects. Whether you are well or ill strong or weak Vitae Ore will give you new life. Under its influence Nature herself cures Rheumatism Dropsy Constipation Sciatica Catarrh Nervous Gout Indigestion Exhaustion Ancemia and all Liver, Blood, and Stomach Diseases. . . . Its effect in giving new vigour and nerve-force to people of mere ordinary health, turning them into noticeably and radiantly strong men and women, makes it worth using in every case. . . . How to use Vitae Ore. Vitae Ore comes to you as a 'box of powder. You simply dissolve it in a pint of cold water, and of this mixture drink a teaspoonful in a half-tumbler of water three times a day, and at bedtime, for a month. In a few days, a week, or later, according to your present condition, you will begin to notice greater strength, better digestion, higher spirits, a clearer complexion, a healthier appetite. These are the effects of the new vitality in Vitae Ore. A 4s. 6d. package contained 137 grains of the substance; analysis showed it to contain a slightly basic but soluble iron sulphate, magnesium sulphate, and combined water; the quan- tity of each constituent was determined and found to be as follows : Ferric oxysulphate, calculated as anhydrous 47.57 per cent. Magnesium sulphate, calculated as anhydrous ... 15.89 ,, Water, in combination 36.54 ,, No other substance was detected. The iron, magnesium, sulphate, and water were all determined separately, and, as the figures add up to 100.00 per cent., not much is left for "some untraceable element defying the chemist's analysis." If the directions, quoted above, are followed, each dose would contain : Iron oxysulphate, anhydrous 0.47 grain. Magnesium sulphate, anhydrous 0.15 ,, The estimated cost of the ingredients contained in one pack- age is about one-eighth of a penny. COCAPHOS. This preparation is supplied by a firm in London. A box priced 4s. 6d. contained 94 tablets. The following extracts are from an advertisement in a maga- zine-: Gavin's " Cocaphos " Puts New Life Into You. . . . You cannot do your work if you are in a nervous state ; the worry and stress of modern life tells on the best of constitutions. Many fly to stimulants and find temporary relief, but as there is always reaction, they find it necessary to continue taking them, and thus a bad habit is formed. When you feel run down and need energy and go the finest thing to take to brace you up and allow you to make the most of your opportunities, to remove that tired feeling, and to build up your nervous system is " COCAPHOS." This is composed of the finest ingredients for the purpose, acknowledged bj the Medical Profession to be a fine recuperative tonic. The dose is given on the label as " One tablet after each meal." 50 The tablets were sugar-coated, and coloured red externally ; after removal of the coating the average weight was 3.9 grains. Analysis showed the presence of: In one tablet. Iron hypophosphite 20 per cent. ... 0.78 grain. Quinine sulphate 2.8 ... 0.10 Extract (probably damiana) about 50 ... 2 grains. Sugar Talc 11 The extract agreed in characters and tests with extract of damiana; it was not possible to determine exactly how much was present. The name of the article appears to imply that a preparation of coca is present; no evidence was obtained of any, but a small proportion of extract of coca, if present, could not be identified in the presence of the extract of damiana. The estimated cost of ingredients for 94 tablets is 8Jd. The most costly ingredient is the extract of damiana, which is also the least certain in quantity; probably the figure given is a liberal estimate. DAMAROIDS. The tablets sold under the name " Damaroids " are supplied by a limited company in London at 2s. 9d. and 4s. 6d. per box. A 2s. 9d. box contained 36 tablets. "Damaroids" are thus described in an advertisement: They are a Safe and Sure Cure of General Weakness, Physical Decay, and Loss of Nerve Power, Varicocele, etc., etc. They are a Unique and Wonderful Specific for men. Effectually Restore Lost Vitality and Stamina, counteract result of late hours, etc. " Damaroids " is The True Nervo-Spinal Tonic, the Safest and most effective medicine yet introduced for nervous and all exhausting diseases. They have cured thousands of cases and they Do cure. On the label they are described as : A Safe and Sure Remedy for General Weakness, Spinal Exhaustion, Neurasthenia, Physical Decay, and Loss of Nerve Power. Directions : One to be swallowed three times a day, after meals. The tablets were sugar-coated and coloured red externally ; after removal of the coating they had an average weight of 3.9 grains. They exactly resembled the tablets just described 51 as " Cocaphos " and showed the same composition, with some difference in the proportions of the ingredients. The figures arrived at are: In one tablet. Iron hypophosphite 14.2 per cent. ... 0.55 grain. Quinine sulphate 3.4 ,, ... 0.13 Extract (probably damiana) about 50 ,, ... 2 grains. Sugar Talc 16 The same remarks apply here as in the preceding case, and the cost would be approximately the same, about 3d. for the ingredients of 36 tablets. INVIGOROIDS. The tablets sold under the name Invigoroids are supplied from an address in Yorkshire at 2s. 9d. per box containing 54 tablets. They are thus described in a circular : Invigoroids are a pure and powerful nerve and organic tonic and food, designed to replace (at a reasonable price) the highly priced and pernicious remedies that are so common. With results much more beneficial and yet with no evil after-effects, Invigoroids are worth their weight in gold to suffering, sorrowful men, and are regularly prescribed by leading specialists. Invigoroids create blood, nerve force and energy. Fill weak and worn-out men with healthy life and rampant vigour. Make existence a perfect pleasure, and render the system disease-proof and capable of sustaining prolonged exertion in any form. The only Cure for Impotence in Men. . . . We Speak to You If your complaint is amongst the following : Back Pains, Brain Fag, Dejection, General Weakness, Head Pains, Hysteria, Impotence, Loss of Flesh, Lost Vitality, Nerve Paralysis, Nervous Debility, Senile Decay, Unnatural Forebodings, Weakness of Generative Organs, etc. In a newspaper advertisement it is stated that : Invigoroids contain free phosphorus (nerve and brain food) and rare herbal blood and flesh-forming specifics. The directions on the label were : ' ' Take one three times daily." The label was printed, " Take two, twice or three times daily," but this was altered in ink, not very clearly, tx> the preceding. The tablets were sugar-coated and coloured red externally ; after removal of the coating they had an average weight of 2 8 grains. Analysis showed the presence of asafcetida, ferrous carbonate, zinc phosphide, strychnine, brucine, and sugar of milk. The alkaloids were probably added in the form of ex- tract of nux vomica, and the amount of this is calculated from the proportion of alkaloids found ; the asafcetida was estimated from the proportion of resin found. The results of tests for the zinc phosphide were somewhat obscured by the other sub- stances present; the amount was calculated from the propor- tion of zinc found. The ferrous carbonate is calculated as the official saccharated carbonate. The formula so arrived' at is : In One Tablet. Extract of nux vomica 1-0 per cent. ... 0.028 grain. Zinc phosphide 2.4 ... 0.067 Saccharated carbonate of iron ... 18.0 ,, ... 0.50 Asafcetida 9-0 :.. 0.25 Sugar of milk. The package was not labelled " Poison," although it would appear to come within the schedule of the Poisons and Phar- macy Act. The estimated cost of the ingredients for fifty-four tablets DR. MORGAN'S RADIO-VIMETTES. This preparation is supplied by a limited company in London at 2s. 9d. per box, containing 20 pills. They are advertised in the following terms : Proved by thousands to be unsurpassed in restoring lost vitality and strength in all cases of Debility, Nervous Exhaustion, Lost Vitality, Varicocele, and all Diseases of the Blood, Nerves, and Brain. Not a quack remedy, but compounded from the Private prescription of a celebrated Doctor. A supply was obtained by post, and a few days later a letter was received from the makers as follows : Dear Sir, We sent you a week ago a course of Dr. Morgan's " Radio- Vimettes," and as in every case in which these are snt, we take, not merely an interest to sell the Vimettes, but a genuine interest in your ailment and its cure, we are writing now to know just what benefit has accrued from the course of treatment you have had. If your case is a mild one we have no doubt that by this time your nerves are strengthened, your energy restored and your general vitality and health renewed, and it only remains for us to say how glad we are that the Vimettes have once more vindicated their claim to supremacy. 53 If, on the other hand, you had not regarded the first signs of disease and wrote us only when nature positively demanded relief from suffering we know that you cannot possibly be ENTIRELY CURED, and if such is your ailment, our interest in its eradication still continues firm. For all such ailments our primary desire is to relieve, and should you still be suffering we beg you to let us know AT ONCE, not merely saying " I am not cured," but by writing a quiet, friendly letter saying just how you feel, giving particulars of your case, the cause and the result. Direct this to " The Specialist " marked " Private," and it will then be read only by him, regarded by him as most strictly confidential and, if desired, returned to you. Enclose a stamp for return postage and you will then obtain full advice on your case FREE OF ALL CHARGE, and we sincerely trust that by so writing health, strength, and vitality may be yours again. A leaflet was enclosed on " Special Courses of Radio -Vimette Treatment," from which it appears that there are three such courses, referred to as: "No. 1. Neurasthenic; No. 2. Urinary; No. 3. Impotence." The Courses of Treatment in each case enumerated above are put up in two forms, the supply being sufficient approximately for one month's treatment. No. 1. SPECIAL STRENGTH for mild cases, 11s. per Course, Carriage Paid. No. 2. CONCENTRATED for severe cases and cases of long standing, 21s. per Course, Carriage Paid. The best advice of the Specialist is at the services of every Patient free of all charge, and in every case correspondence is treated in the strictest confidence. A list of questions to be answered was also sent. The dose is given, in a circular of " General Directions," as follows : The Ordinary Strength Radio-Vimettes will be found sufficiently power- ful for all mild cases of Nerve trouble, such as NERVOUS DYSPEPSIA, HEADACHES, etc. For these troubles One Radio-Vimette should be taken night and morning after meals. The pills were ovoid in shape, sugar-coated, and coloured purple externally. After removal of the coating they had an average weight of 3.7 grains. Analysis showed the presence of free phosphorus, reduced iron, quinine sulphate, and excipient. The amounts found were : In One Pill. Reduced iron : 70 per cent. ... 2.6 grains. Quinine sulphate 11.8 ,, ... 0.44 grain. Phosphorus 0.13 ... 0.005 The estimated cost of the ingredients for twenty pills is d. 54 GORDON'S VITAL SEXUALINE RESTORATIVE. This preparation and a number of others are supplied by a firm in a Yorkshire town. The price of this " restorative " is 22s. per bottle, holding 21 fluid ounces. The usual advertisement is of a pamphlet called " Strength, How Lost, How Regained," which is thus referred to: Interesting and instructive remarks to young and middle-aged men on " How to Preserve Strength and Eetain the Powers." A Brief Treatise on Nervous Exhaustion, Loss of Strength, and Debiltiy in Men. This book not only contains valuable remarks on how to preserve Strength and retain the Powers to an advanced age, but points out the beet means of restoring Exhausted Vitality, Poverty of Nerve Force, Mental Depression, and will especially interest those who wish to create Vitality, increase Nerve Stamina, renew the Vital Forces, or fit themselves for business, study, or marriage. The pamphlet is further entitled : " A Confidential Treatise on Nervous Exhaustion, Spermatorrhoea, Vari- cocele, Generative Weakness, Debility, Special Diseases and Urinary Derangements in Men, THEIR CAUSE AND CURE, By Concentrated Herbal Remedies. A Popular, Practical, and Moral Exposition of Some of the Fundamental Problems of Sociology. By Charles Gordon, P.M.B." " P.M.B.," it may be noted, does not represent any known medical qualification, but is of unknown signification, and is probably intended to suggest to the ignorant some sort of medical degree. It is a booklet of 43 pages, with sections on Onanism, Sper- matorrhoea, Marriage, Varicocele, Impotence, Gonorrhoea, Gleet, Syphilis, etc. An " advice form " was also sent, con- taining a list of questions to be answered by those desiring medicine. A price list gives the prices of the following : Vital Sexualine Restorative (described as '" for Onanism, Night Emissions, Seminal Losses, Waste of Vitality, Brain Fag, Depression, General Weakness, Loss of Energy, Nervous Debility, Sperma- torrhoea, and Varicocele "), Viro-Erectile Elixir, Anti- Syphilitic Mixture, Bubo Compound, Gleet Compound, Gonorrhceal Mix- ture, and Gravolene, all at 22s. per bottle, and Gentiana Tonic and Varixolene Liniment, at 11s. per bottle. On the label of the " Vital Sexualine " it is called: The Great Nerve Restorative, Brain Fertilizer, and Vital Tonic. Feeds, Strengthens, and Sustains the Nerves, prevents Losses and waste of 55 Vitality, Creates Nervous Fluid, Brain Matter and Nerve lorce. Brightens the intellect, improves the memory and mental faculties, restores strength, and promotes a renewal of life in the entire system. A proven remedy for all weakened conditions of the system dependent upon the deficiency of the vital forces. Permanently Cures Neurasthenia, Nervous Breakdown, Brain Fag, Depression, Loss of Energy, Sleeplessness, Nervous Headache, Melan- cholia, Trembling, Poverty of Nerve Force, Nervous Prostration, General Weakness, Loss of Strength, Exhausted Vitality, Premature Decay, Brain Wreckage, Neuralgia, Nerve Tire, etc. Dose. One small teaspoonful in a wineglassful of cold water three times a day, immediately after meals. The liquid was reddish-brown in colour, and syrupy. Analysis showed it to contain : In One Dose. Iron hypophosphite 0.50 part ... 0.27 grains. Calcium hypophosphite 0.50 ... 0.27 ,, Sodium hypophosphite 0.60 ... 0.32 Potassium hypophosphite 0.14 ,, ... 0.07 ,, Quinine sulphate 0.50 ... 0.27 Citric acid 0.90 ... 0.48 Sugar (approx.) 51 parts Glycerine ,, 36 parts by measure Colouring matter Water to 100 Metallic hypophosphites are not generally considered to be "concentrated herbal remedies." The estimated cost of the ingredients for 21 fluid ounces is 10|d. THE MARSTON TREATMENT. This is supplied by a firm in London, and is advertised as f ollowe : EVERY MAN Suffering from GENERAL and PHYSICAL DEBILITY should send for a Valuable Pamphlet explaining how all Nervous and Organic Derangement may be successfully treated without stomach medication. The method is easy and pleasant, and will effect a perfect and permanent cure. Sent in a plain sealed envelope post free 2 stamps. Application to the address given brought a paper-covered book of seventy-two pages, entitled A Treatise on the Modern Treatment of Nervous Diseases and Exhaustion in Men by 56 Local Absorption, the scope of which is indicated by the follow- ing extracts : The object of this treatise is to describe, in as clear and simple a manner as possible, for the non-professional reader, the various diseases and affection* resulting in the nervous and sexual systems from the indul- gence of early pernicious habits, excessive venery, fast living, and other irregularities, the product of our modern civilisation. . . . In issuing this edition of our treatise on NERVOUS DISEASES, we desire especially to point out that ours is not an empirical or secret treatment, nor do we use merely one single preparation and designate it a cure-all and panacea for every variety of disease. On the contrary, the Remedies used are varied, and such as long experience in the treatment of Nervous and Sexual ailments have proved to be the most valuable in their cure. Our object is to prescribe the course necessary to be taken to ensure the result expected or hoped for ; we claim no new or occult discoveries in the domain of Medicine or Pharmacy, but we do claim that our method of combining medicinal drugs, in the form of a suppository and applying them directly to the immediate locality of the diseases described in this treatise, is not only more successful in its results but is more effectual and rational than purely stomach drugging for nervous Diseases allied with sexual troubles. The book was accompanied by various other papers, and a letter from which the following extracts are taken : If for any reason after a perusal of our book you are unable to select the course of treatment necessary, you may give us a full and as clear a statement as possible of your symptoms, and we will submit it to the consulting physician, when such course as will meet the requirements of your case will be prescribed. The treatment can be sent to you by post, together with the necessary medical and hygienic advice suitable for your case. Should you still have any doubt as to the advantages of rectal treat- ment in your case, possibly owing to some complication that does not enter within the scope of our treatise, we shall be glad to hear from you, and any letters will be treated in the fullest confidence. Consultation personally or by letter free of charge. In a subsequent letter the following occurs: We are well aware that there are firms in existence which treat ner- vous debility on similar lines to our own, but we again emphatically claim and challenge all rivals to contradict the fact, viz., that we are the oldest established advertising medical business, and that we were the first to originate the Rectal Method for the cure of Nervous and Sexual Diseases. From the papers sent it appears that five kinds of treatment are supplied, as follows : Graded Course for the cure of Seminal Losses, Spermatorrhoea, etc. 57 Impotence Course for the cure of Impotence, Loss of Sexual Vigour, Erectile Power, etc. Urinary and Prostatic Course for all troubles of the Prostate Gland, Bladder, Kidneys, etc. Developing Course fox Atrophy or Wasting and Shrinkage of the Organs, etc. Neurasthenic or Nervine Tonic Course for General Weakness, Debility, Loss of Memory, Sleeplessness, Melancholy, Despondency, Depression, Neuralgia, Brain Exhaustion, and all those conditions arising from Debility asociated with Nervous Diseases. The price of the treatment is the same in all cases, namely, 1 Is. for one month's treatment, and 2 2s. for three months' treatment, of any course. In a third letter it was stated that To convince you of our confidence in our Treatment to effect your cure, we will send you a three months' course of treatment upon receipt of One- Half the Regular Price, namely, 21s., and you need not pay the balance of 21s. unless you are perfectly satisfied with the results. A guinea was accordingly sent for a three months' supply of the Nervine Tonic Course ; this elicited a request for answers to the printed questions that were sent, and a sample of urine, for "our Consulting Physician." The question paper was there- fore filled in with particulars of an imaginary case of nocturnal emissions, and sent with a sample of normal healthy urine to which some glycerine and water had been added. Three boxes of suppositories were received, with a letter, of which the principal parts were as follows : We have your favour with answers to questions and sample of urine enclosed, and our Consulting Physician has submitted the latter to a careful examination, and we are pleased to inform you that it was found to be of normal specific gravity, and showed no evidence of any organic kidney disease, but an examination of fche urinary debris, together with the statements made in the diagnosis form discloses sufficient evidence to convince us that your nerve and sexual system is very much below par, and in order to bring about your complete restoration to sexual health and strength it will be necessary for you to undergo the treatment our Consulting Physician has prescribed in your case. . . . You will therefore see that it is absolutely necessary in your case for you to undergo, in addition to the Tonic Course which you ordered in your previous letter, a three months' treatment of the Graded Course to permanently check all losses either at stool, in your urine, or by nightly emissions, and by this means a reinvigoration of the exhausted seminal secreting organs will be gradually effected. This course could be used every night whilst you are using the Tonic Course every morning . . . 58 we forward you herewith a three months' treatment of the Tonic Course. . . . Use from box No. 1 the first month, box No. 2 the second month, and box No. 3 the third month. ... If you would like to follow our advice and use the Graded Course at night and will remit the reduced fee of 21s. for the same, the further remedy will be at once prepared and sent you. . . . Each box contained 29 suppositories, or 87 in all, having an average weight of 16| grains. All three kinds were found to be similar in composition ; they differed a little in the proportions of the ingredients, but, as the drugs are not soluble in the fat, suppositories of such a composition, if prepared by melting and pouring into moulds, would show such differences in strength as those found, unless prepared in very small quantities and with extreme care. The composition shown by analysis was : No . 1. No . 2. No 3. Per Cent. Grains in One. Per Cent. Grains in One. Per Cent. Grains in One. Calcium hypophosphite Powdered gentian and pow- dered cinchona bark Oil of tbaobroma C-4 2-1 97'5 0-07 0-35 0-3 3-7 96 '0 0-05 0-61 0-3 2-7 97'0 0-05 0-45 The two vegetable drugs could not, of course, be determined separately ; they appeared to be present in something like equal quantities. The estimated cost of the ingredients for the eighty-seven suppositories (ordinary charge 42s.) is 5d. MURRAY'S COMBINED TREATMENT. This " treatment," which has so great a resemblance in many respects to the preceding as to suggest that it can hardly be merely accidental, is supplied by another London firm. It is advertised as follows: BOON TO MAN. All Men suffering from Nervous Exhaustion, Physical Debility, and all Allied Troubles, should send for my Illustrated Book, fully describing Symptoms, together with most modern scientific method of cure, including hundreds of testimonials of complete cures. No Trusses. No Electricity. Sent sealed Post free two stamps. On application to the address given two paper books and a small pamphlet were sent. The first entitled The Combined Stomach and Rectal Treatment for the Permanent Cure of Nervous Debility and Sexual Diseases, including Sper- matorrhoea, Impotence, and other Disorders, resulting from these Conditions, is a booklet of eighty-four pages, from which some extracts are given below ; the second is a booklet of forty pages, entitled Varicocele: Its Symptoms and Cure; and the pamphlet, of eight pages, is entitled A Treatise on Venereal Diseases Gonorrhoea, Gleet, Stricture, etc. The "Treatment" is thus explained: The present therapeutic methods of treating Nervous Debility may be described as three distinct systems, viz. : Treatment by the Stomach alone, Treatment by Local Absorption, through the means of the Rectum or opening of the lower bowel, and >tihe Murray system of combined Rectal and Stomach Treatment. The two former methods used separately Have proved of considerable advantage in removing some of the distressing symptoms of this disease, but the successful cure of Nervous Debility, needless to say, depends upon the cure and removal of every symptom associated with the disease. . . . This result is effected by "Murray's Treatment," which has received the appellation " Combined " from its peculiar means of administration. It comprises two forms of treatment. The first consisting of prescribed remedies taken by means of the stomach. . . . The second form . . . . is that of a Rectal Suppository. The books were accompanied by various papers and a letter of the usual type, which was followed at intervals by others, in one of which it was stated that: It is always the earnest endeavour of my Consulting Physician to carry out to a successful issue the many cases that come under our care, and I am glad to say that the results 'have in no way contradicted my claims as to this satisfactory issue. In all cases that are submitted to my opinion, it is honestly given after consulting -with my Physician, and in no case do we encourage or give hopes of a successful cure in those chronic cases which sometimes do not yield to treatment. From the book it appears that five "courses " are supplied namely : The Nervine Tonic and Brain Food Course. The Seminal Course. The Impotence Course. The Genito-Urinary Course. The Atrophy Course. From a long and varied experience in the treatment of Nervous Debility my Physician and myself find it very requisite that three months' treat- ment should be prescribed in order to bring about a thorough and complete cure. The fee for a three months' Treatment is 2 2s. The fee for a month's Treatment is 1 Is. 60 No order having been sent, a further letter was received, containing the following offer : . - . . . I shall be most happy to make such reduction in the cost of the treatment as I hope will adapt itself to youi means ; and to show you the confidence I 'have in the value and benefits of my method of cure, I am willing to meet you in the matter of payment, and would suggest your paying me, say, 20s. for a three months' course, and the balance of 22s. I shall only expect or look for, provided that you are perfectly satisfied with the results obtained from its use. Twenty shillings was then sent for the " Nervine Course," and brought a request for answers to the questions on a sheet forwarded, and a sample of urine. The questions were answered in the same way as for the Marston Treatment (above), and a sample of the same mixture of urine, glycerine, and water was sent. Not only was the result the same, that is, a discovery that an additional course at an additional fee was necessary, but it was conveyed in very similar words: It is evident that your case is more complicated than your first letter indicated, and from the full particulars to hand, together with result of examination of urine, your case needs in addition to the Nervine Tonic Course a Special Seminal Course to permanently check all seminal losses, whether at stool, in the urine, nightly or otherwise, and it will strengthen the now weakened seminal secreting ducts. This extra Course would have to be used in the morning, and in conjunction with the night Course they will act in harmony with each other and attack every symptom of your case. ... I shall be pleased to let you have this extra Course on the same reduced terms, viz., 20s., and upon receipt of this amount it will immediately be prepared and sent you with full directions, and I trust you will see your way clear to order the same at once so that they may be used conjointly. The preparations sent consisted of three boxes of gelatine perles (called " gelatinoids ") marked " No. 1," " No. 2," and " No. 3," each box containing 10, and three boxes of supposi- tories, similarly marked, each containing 30. It was explained that: I am only sending you the first month's gelatinoids, as it may be neces- sary to modify these next month. The general directions were to use a suppository from box No. 1 first day, box No. 2 second day, and box No. 3 third day, recommencing with box No. 1 again on fourth day, and so on in this order day after day. The Stomach Gelatinoids are to be swallowed and in same alternative order as Rectal Treatment. The directions on the gelatinoids were ' ' Take one every morning after breakfast." 6.1 Gelatinoids No. 1. Each contained 0.75 grain of quinine sulphate, partly dehydrated, equivalent to 0.84 grain of the B. P. salt. No other substance was present. Gelatinoids No. 2. The contents of one had an average weight of 1.35 grains, and contained : Ferrous phosphate (Pe 3 2P0 4 ,8H 2 0) , 26 per cent. Quinine phosphate (Q 2 H 3 PO 4 ,8H.,O) 35 Strychnine. Talc 11 Milk-sugar. The strychnine was only a small proportion of the alkaloid, and the amount of material available did not suffice for its separate determination. Gelatinoids No. 3. The contents of one had an average weight of 1.66 grains, and consisted of a brown extract agreeing in most characters and tests with extract of damiana. No other ingredient could be detected, but some other extract might have been present, as a mixture of some vegetable extracts could not be separated with suoh a small quantity as was available. The estimated cost of the ingredients of the 30 gelatinoids is l|d. The Suppositories. All the three kinds of suppositories had the same constituents, only showing such email variations in the amounts as would be inevitable in making a large quantity in the usual way; the average weight was 16 grains. Analysis showed the presence of : No. 1. No. 2. No. 3. Per Grains Per Grains Per Grains cent. in One. cent. in One. cent. in One. Calcium hypophosphite Powdered gentian and pow- dered cinchona bark 4-05 3-90 0-7 06 3-54 4-30 0-6 0-7 3-70 5-30 0-6 0-9 Oil of theobroma 92-05 92-16 91-00 In the mixture of powdered gentian and cinchona, the former appeared to constitute more than half. The estimated cost of the ingredients for 90 suppositories is 5|d., and therefore of the entire " combined treatment " 6Jd. 62 SEQTJARINE. Sequarine is supplied by a firm in London, at the price of 8s. a bottle, holding 1 fluid ounce. It is advertised as " The New Serum Cure," and both newspaper advertisements and the descriptive pamphlet sent on application include what is stated to be a portrait of " The Discoverer, Dr. Brown- Sequard, F.R.S." It is stated in the pamphlet that: Since the discovery of blood circulation by Harvey there has been no greater addition to the forces of medical science than the strength pro- ducing element discovered by Professor Brown-Sequard, F.R.C.P. (Lon- don), L.L.D. (Cambridge). This element, which is the Serum-Sequarine, has already become an indispensable aid to physicians. . . . The new serum has been given various names, such as " Sequard Fluid " and " Spermine," etc., but the regisitered and generally recognised name of Professor Brown-Sequard's discovery is "Sequarine" a name derived from that of the discoverer himself, thus : Sequar ine. Since the general nature of the preparation is thus indicated, it is not altogether a "secret" remedy; but from the way in which it is advertised to the public, and the attempt to identify Brown-Sequard's orchitic fluid (which, of course, is not a serum) with the preparation supplied by this particular firm under a registered trade name, it is fairly to be classed among nostrums. The following is an extract from a newspaper advertisement: Nature and Action of the Serum. According to leading physicians the nature of Sequarine and the manner of action on the human organism in curing disease may be briefly sum- marised as follows : Within every animal body there exists a " power of disease resistance," the principle of " natural immunity " ; this power resists Ithe entrance of any disease into the body, and if it is of normal strength readily repels the disease even after it has gained entrance. In treating disease doctors are aided greatly by the principle of "natural immunity." The homoeo- paths rely on it almost entirely and in a great many instances drugs get the credit for a cure when vital resistance has really effected it. The greatest scientists have always been baffled in their endeavours to discover the element or force which is the basis of this peculiar power. In his search for this element Professor Brown-Sequard discovered that there exists in the blood infinitesimal quantities of a fluid which subsequently proved to be the basis of the power of natural immunity from disease. This fluid is the serum which has been named Sequarine in his honour. 63 What Sequarine Cures. Sequarine is a cure for any ailment or weakness brought about by lack of nerve power or an accumulation of impurities in any part of the body. The attempt to secure the prestige of the name of the late Dr. Brown-Sequard, without stating precisely that he was in any way responsible for the article now sold as Sequarine, is very obvious in a circular letter sent with the pamphlet referred to above, from which the following is an extract: Since the introduction of Sequarine into England an ever-increasing number of sufferers have taken this treatment with remarkable success. The name of Dr. Brown-Sequard, L.L.D. (Cambridge), Fellow of the Royal Society and Fellow of the Royal College of Physicians (London), is a sufficient guarantee of its efficacy. The directions on the label are: Dose. Adults, 20-30 drops; children, 5-15 drops in half-a-glass of water (soda-water or water which has been previously boiled preferred). To be taken three times daily, half-an-hour before meals. The liquid contained 35.8 per cent, by volume of alcohol, and a sufficient trace of oil of peppermint to give a flavour ; on evaporation it left 1.9 per cent, of solid residue, of which 0.6 was ash principally sodium and potassium phosphates. The nitrogen present was 0.22 per cent., equivalent to 1.4 per cent, of protein, but a small portion of it was present as ammonia, perhaps formed by decomposition of nitrogenous organic matter. The liquid was thus shown to be of the nature of an animal extract, with alcohol ; definite constituents could not, of course, be isolated. NEUROVRIL. The preparation known as Neurovril is supplied by the Neurovril Company, London. The price is 21s. per bottle, " sufficient for one month," or 7e. 6d. for a smaller bottle, "sufficient for one week." The smaller bottle was found to contain nearly 3 fluid ounces. An advertisement occupying the space of a column in a London daily paper, is headed, in large letters, HAS THE ELIXIR OF LIFE BEEN DISCOVERED? Amazing Results of Great Health Discovery announced To-day. 64 And the first paragraphs are as follows: There is announced to-day a mysterious serum, which, whilst according relief in cases of severe illnesses, apparently, from the statements made, actually introduces into the body not a mere stimulating force, but life itself. Although the discovery has been made by a Continental scientist, he has already sent (particulars 'to his confreres all over the world, and so important do British scientists consider this matter, that they are making every effort to place the information at once in the hands of those who are ailing. The amazing successes that have attended the application of this won- derful new health discovery have aroused on all hands the question : "Has the Elixir of Life at last been discovered?" After much more of the same sort, it continues : The new serum is a new food for use in cases of Loss of Memory, Melancholia, Headache, Irritability, Exhaustion, Slackness, Nervous Weakness, Nervous Prostration, Brain Fag, Partial Paralysis. It is a blood food for use in cases of Ansemia, Impoverished Blood, Rheumatism, Kidney Troubles, Sciatica, Disordered Liver. It is a physical food for use in cases of Wasting Tissue, Thinness, Lack of Muscular Vigour, Aged Appearance, Weak Back, Premature Decline. The wonderful result after even the first dose will be a delightful sen- sation to those who have long lost the vigour of full manhood or woman- hood. A booklet is sent on application, from which the following passages are quoted: When it is said that old men and women are made young, that the decrepit take on a new virility, that the yellow-hued cheeks assume the roses of youth, and the worn out brain gains new power to think and control action these are facts beyond all disputing. The great new basic serum makes it possible to defy the approach of age, and, better still, enables men and women to come back from the realms of senile decay and continuous illnees to the vigour of perfect man and womanhood. Tissue by tissue, new flesh, new energy-creating cells are formed, and as the basic serum is absorbed into the system, through- out the whole body is carried on a work of rejuvenation. Realising the inutility of conducting investigation on stereotyped lines elaborate search was made for a new idea, and in a most singular manner the secret that proved the keynote of our scientist'* success was found His work Involved ceaseless laboratory experiments through the realms of organic chemistry and physiological science, and demanded abnormai patience. . . . 65 Further experiments proved that the new basic serum not only supplied vitality and strength to the body, but could be prepared in such a way as to prove an anti-toxin, a means of resisting and curing illness .... To Bay that Neurovril contains protoplasmic life is no rash assertion ; it is a perfectly true statement proven by exhaustive laboratory tests. Teeming with millions of life centres, every drop of Neurovril intro- duced into the body effects a wonderful change. The life centres develop and give up their energy to the body The following appears on the label : Analysis of Active Principle : 75 per cent, phosphates, immediately assimilable. 20 ,, albumen, remarkable for creating virility. 2 ,, carbonate calcic. 3 water. Total = 100 per cent. The directions are: Take of Uhis Tonic, regularly, .half of a Neurovril glass (supplied with this bottle) night and morning directly after meals. " Half of a neurovril glass " is about 5 fluid drachms. Analysis showed that 100 parts (by measure) of " neurovril " contained 18.9 parts (by measure) of alcohol, and gave 19.1 parts of residue on evaporation, of which 18.1 parts consisted of sugar. A trace of oil of cloves was present, giving a slight clove odour, and a faint odour like that of an animal extract in a state of incipient decomposition could also be detected. The liquid was slightly turbid, and a trace of fatty substance was present. No appreciable amount of "serum" or other animal substance was present; only the slightest indication of a trace of nitrogenous matter could be detected, this being of the nature of an organic base, and the amount of phosphate was so small that it was doubtful, even with a very delicate test, whether any at all were present. The total ash was 0.03 per cent., and it contained a little lime. The 1 part per 100 fluid parts which was not sugar was probably chiefly glycerine, but a small quantity of glycerine in presence of a large quantity of sugar can hardly be positively identified by examining a reason- able quantity of the material. If the "active principle" contains, as stated on the label, 75 per cent, of phosphate and 20 per cent, of albumen, it fol- lows from the analysis that only a minute trace of it is present in the liquid, which is practically a mixture of simple syrup and diluted alcohol. 66 OSOGEN. Osogen is Supplied by a firm in London at 2s. 9d., 7s. 9d., and 11s. a bottle. A bottle price 2s. 9d. was found to contain 1 fluid ounce, and a bottle price 11s. 5 fluid ounces. An advertisement, occupying the space of a column in a London daily paper, is headed : MYSTERIOUS SERU-PHOS. Amazing Elemental Combination Startles Scientists. More Effective than the most powerful Serum. Some extracts from it are : Scientific discussion is at present rife anent a mysterious new combina- tion of organic elements. Some time ago Professor Brown-Sequard, F.R.S., F.R.C.P. (formerly head of Queen Square Hospital, London), discovered a serum (Sequard Fluid) which was used with success in treating various ailments. Another eminent scientist has now discovered that by combining this serum with organic reconstituent elements its curative value is more than doubled. After Professor Brown-Sequard announced his discovery to the Paris Biological Society, Professor Prince Tarkanhov (St. Petersburg) and other scientists began experiments with the serum, and hence the new remedy is a direct product of the labour and learning of some of the greatest scientific men of their age. This seru-phos combination (called Osogen) has been pronounced absolutely certain in curative effect and more swift in a-ction (than the most powerful Berum used alone. Scientists who investigated it were amazed by its wonderful potency, and Physicians, both in London and on the Continent, predict that Osogen will supersede many other forms of treatment Osogen is not a secret remedy. It is a vital extract (C-jHsN,), com- bined with organic reconstituent elements (glycerophosphates), all of which are now recognised by the Medical Profession, and appear in Pharmacopoeias throughout the world. One of the ingredients has been called by famous scientists " More powerful than the interchange of blood." The whole is almost an exact replica of the elements which combine to form the human economy. The vital extract increases disease-fighting corpuscles, another constituent forms nerve cells (espe- cially cells of the Spinal Nerves), another forms tissue cells, etc. It* action is restorative in every part of the body, and its use is especially recommended in cases where the serum alone has not effected a thorough cure. In a small pamphlet enclosed in the package, " Osogen " is described as Serum and Glycerophosphates. A Natural Remedy for Neurasthenia, Nervous Disorders, Brain Fag, General Debility, Araemia, Brigfhit's Diaease, Influenza, Sciatica, Functional Weakness, Loss of Vital Power, Indigestion, Dyspepsia, Rheumatism, Kidney Disease, Dropsy, Diabetes. Asthma, Consumption, Locomotor Ataxy, and Paralysis. 67 The directions on the label are : 20 to 30 drops in a wineglass of water after meals three times daily. Children over six : 5 to 15 drops as above. Analysis showed the liquid to contain glycerophosphates of iron, magnesium, sodium and quinine, a little alcohol and a trace of chloroform, with glycerine in large quantity. Not more than a trace of nitrogenous matter was present in addition to the quinine, showing that if the mixture contained any of Brown-Sequard's Orchitic Fluid, the amount was very small. Determination' of the quantities of the various ingredients gave the following formula: Quinine glycerophosphate 0.75 part Iron glycerophosphate 2.14 parts Magnesium glycerophosphate 0.77 part Sodium glycerophosphate 0.90 ,, Spirit of chloroform 3.8 parts by measure Glycerine 73 Water to... ....100 DR. LECOY'S VIGOROIDS. These consisted of sugar-coated tablets, coloured blue exter- nally. After removing the coating, the tablets had an average weight of 2.2 grains. The dose is stated to be two, three times daily. Analysis showed them to contain : Ferrous phosphate. Quinine. Strychnine. A vegetable extract. Sugar. Starch. Talc. The ferrous phosphate, calculated as Fe 3 (PO 4 ) 2 8BUO, from the iron found, was 8.7 per cent., or 0.19 grain in each tablet. The quinine and strychnine together amounted to 4.35 per cent., or 0.09 grain in one tablet; the strychnine was clearly not more than one- twentieth of the total alkaloid (= 0.005 grain in one tablet), but it was not possible to determine the amount exactly on the quantity available. The vegetable extract showed no well-marked properties by which it could be identified; the amount was small, the sugar constituting the largest part of the tablet. ANTINEURASTHIN, A BRAIN AND NERVE FOOD. Readers of daily or weekly papers or magazines who allow their eyes occasionally to travel over the advertisement pages of these journals can hardly fail to have seen somewhat fre- quently a lengthy advertisement of a preparation called Dr. Hartmann's Antineurasthin. The advertisement is usually headed " The Twentieth Century Disease." This, it appears, is neurasthenia, and the various stages of its manifestations are set out in a sort of table, beginning with " Sensitiveness " and end- ing with " Suicidal Tendency." Antineurasthin, referred to as " this marvellous twentieth century brain and nerve food dis- covery," is put forward as a specific for the cure of neurasthenia : Dr. Hartrnann's discovery is one that should personally and very deeply interest braii.- workers in all walks of life. Every day are heard and seen all too serious evidences of the undue strain of their intense work on the vital power of the body. And now, on the highest possible authority, it is heralded that science has proved equal to the stern necessity which demanded the discovery of " Antineurasthin," the brain and nerve food. For greater convenience " Antineurasthin " is compressed into small tablets, and although its beneficial effect on the brain and senses is so immediate, yet there is none of the depressing reaction that follows the administration of artificial drug stimulants, " Antineurasthin " being a special brain and nerve nutrient, and not a brain and nerve drug-irritant. No longer need the brain-worker struggle on under the cloud of fear of failing powers of brain and body. He or she may, by including " Anti- neurasthin " as an article vitally necessary in the daily dietary, build up and maintain that perfect balance of mental and physical power which alone can uphold health and happiness. It appears that this article was sold in Germany before being introduced here, and it was included in the series of proprietary preparations analysed by Dr. Zernik. According to Zernik's analysis, it consists of dry yolk of egg, milk sugar, a small quantity of starch, dextrin, and an aromatic substance. A detailed quantitative analysis of " Antineurasthin " as sold in this country gave the results described below. A 4s. 6d. box contained twenty-four tablets, having an average weight of 30i grains each. The directions are: To be taken when and as required, particularly before or after great exertions (bodily and mental) ; in all cases of nervous disorders and mental affections, general debility, etc Usual dose 3-4 tablets a day between meals. Antineurasthin contains no injurious ingredients, and is therefore absolutely harmless to the most deli- cate, even if taken in large quantities. Analysis showed the presence of : Protein Fat Sugar of milk 32 8 per cent Ash Water Gum Aromatic substances ... traces. Potato starch (by difference) ..................... about 22.0 per cent. The material of the tablets is nearly white, with yellow par- ticles like dried egg-yolk distributed through it ; extraction with appropriate solvents proved a fair trace of lecithin to be present ; if the whole of the fat present were derived from egg-yolk it would represent 3.8 per cent, of dried yolk, equivalent to 7.7 per cent, of fresh liquid yolk in the tablets; this accounts for 1.3 out of the 26.4 per cent, of protein. Sulphur in organic com- bination was found to be present to the extent of 0.09 per cent. ; sulphur is practically absent from the yolk, but occurs in the white of eggs, and the amount found corresponds to 5.4 per cent, of dried, or about 38.6 per cent, of liquid, egg- albumen in the tablet; a further 5.1 out of the 26.4 per cent. of protein is thus accounted for. This leaves 20 per cent, of protein, and this stands in about the same ratio to 32.8 per cent. of milk sugar, and about 5 per cent, of ash (deducting the ash of the egg and gum),' as corresponds to the composition of a dried separated milk. The ash consisted principally of calcium phoa- phate, like the ash of milk. The aromatic substances appeared to include a trace of vanilla and of some other substance that could not be identified ; these are probably added to serve at the same time as flavouring agents and preservatives. The starch was seen by the microscope to be very abundant, corresponding in appearance to the amount required by differ- ence. On the above assumptions the composition of the tablets would be approximately: Dry yolk of egg ................................................ 3.8 per cent. Dry white of egg .............................. ................. 5.4 per cent. Dry separated milk .......................................... 57.8 per cent. Gum ............................................................... 2.0 per cent. Potato starch ................................................... 22.7 per cent Moisture ......................................................... 8.3 per cent. Aromatic substances .......................................... traces. The daily dose of four tablets, or 122 grains, would, according to this formula, contain the equivalent of 10 grains of yolk 70 and 43 grains of white of egg (not dried); the ratio between these is about the same as exists in an average egg, and the two may be put together and regarded as about a teaspoonful of fresh egg; in addition, the daily dose would represent about 2 oz., or a quarter of a tumblerful, of separated milk, and a little starch. A GERMAN NOSTRUM. According to Dr. Zernik : Dr. J. Schafert's physiological nutrient (nerve) salts for neurasthenia is a preparation made in Barmen. The prospectus states that it is com- posed of glycerine phosphate compound with certain physiological salts, which act on the formation of the red blood corpuscles and improve the circulation generally ; 100 grams of the salts p'i*, up in a glass vessel costs 4s. It consists of 40 parts of glycerine phosphate of calcium, 30 parts of glycerine phosphate of sodium, and 20 parts of sodium chloride with a trace of iron. CHAPTEE IV. MEDICINES FOE COUGHS, CONSUMPTION, CATAEEH, ETC. The medicines described in this chapter include both old and new nostrums, and vary from simple pills and lozenges to more or less complex " treatments." The claims advanced for them also vary considerably, but are in most cases very wide. A pill containing ipecacuanha only is put forward, not merely as sometimes useful for coughs, but as " The Best Eemedy to Cure all Coughs, Colds, Asthmas, etc." A lozenge containing cubeb and liquorice is similarly described as " the best article before the public for Coughs, Colds, Bronchitis, Asthma, Catarrh, the Hacking Cough in Consumption, and numerous affections of the throat." These, however, are modest claims compared to some of the others. A lozenge, in which the only medicinal agent found in any considerable quantity was extract of liquorice, is not only put forward for most of the above disorders and others allied to them, but also for " many cases of Headache, Flatulence, and Indigestion." A liquid which is said to be " the best-known remedy for Colds, Influenza, Sore Throat, etc. ," is also described as a valuable remedy for, among other things, diarrhoea, disordered stomach, bad circulation of the blood, and quinsy. The " treatments " are more especially put forward for catarrh, but here, too, the net is cast rather wide; in one case, asthma, whooping cough, croup and con- sumption are among the diseases for which it is put forward as a cure, while in another the comprehensive, if awkward, description of those to whom it is recommended is ' ' all who wish to quickly cure Catarrh, Asthma, Adenoids, Polypi, or other Nose-breathing, Chest or Lung, and Voice or Hear- ing or Throat Bronchial Trouble." Needless to say, theii 72 claims are mutually exclusive ; one of them, an inhalation "treatment," claims to be "the only treatment through which the diseased parts of the head, throat, and lungs can be reached"; while the proprietor of another modestly says: " I assert, without fear of contradiction, that mine is the only apparatus which sends the medicated vapour over every membrane that air can reach, and I also assert with equal firmness that there are no preparations for similar object which can compare in effectiveness with those sup- plied by me." Two of the treatments are supplied at some- what high prices; and, although no exact estimate is given of the cost of the ingredients, it is evident that it is quite out of proportion to the amounts charged for them. FENNINGS' LUNG-HEALERS. The article advertised under this name is in the form of small pills, and is supplied by a firm in the Isle of Wight at Is. IJd. a box, containing thirty pills. The pills are advertised as "The Best Kemedy to Cure all Coughs, Colds, Asthmas, etc." The following quotations are from a circular enclosed in the package : Directions for taking Fennings' Lung-Healers. The Certain Remedy to cure all Colds, Coughs, Bronchitis, Influenza, Incipient Consumption, The Coughs of Measles and Scarlet Fever, Asthmas, and other complaints of the Lungs. The Dose is the same for all ages. These Lung-Healers, although so beneficial in curing Inflammation, quelling Fevers, and eradicating the virus of disease, are perfectly harm- less and innocent, and can with equal safety be given to the most tender infant as well as to the f ullgrown person. To Cure Colds, Coughs, or Asthma. One of these Lung-Healers should be given to the infant, or person, in jam, or by itself, every morning or evening. For Bronchitis, Influenza, Incipient Consumption, the Cough of Measles. of Scarlatina, or Scarlet Fever, give one of the Lung-Healers, in jam, or by itself, three times a day. ... If, when freely taking of these Lung-Healers, the child or person should perchance become sick^ it need not be heeded, or reckoned as a bad symptom, for sickness often proves of great benefit in a complaint, and advantageously assists in lessening all Fevers and Inflammations. 73 The average weight of one pill was 0.22 grain. ChemicaJ analysis and microscopical examination showed that practically the whole of the material consisted of ipecacuanha; the amount of alkaloid present was 1.8 per cent., which is a little below the average for ipecacuanha, and the alkaloid extracted pos- sessed the characters of ipecacuanha alkaloid. Careful search for other ingredients, and comparison with powdered ipeca- cuanha, showed nothing else to be present but the trace of excipient used to bind the powder into pills. Estimated cost of ingredients for thirty pills is id. PEPS. These much-advertised lozenges are supplied by a firm in a Yorkshire town in boxes at Is. ld. and 2s. 9d. per box. A 2s. 9d. box was found to contain ninety -eight lozenges. The name of the article appears to be derived from the initial letters of " Pine extract pastilles." The nature of the claims made is shown by the following extracts from a booklet issued by the makers : In the course of scientific research singular freedom from bronchial disease was noticed among the dwellers amidst the rich pine forests of Europe. The great healing power of the odours and balsams of the pine tree was also observed ; and at last a striking connection between the two facts made itself apparent. . . . A study of the peculiar property of pine balsams led to their great medicinal value becoming more fully recognised, and the idea was evolved of capturing and storing up these rich essences in some form convenient for the great masses who are not able to spend winter in the far-famed forest resorts. It was practically a matter of finding how to transfer to our crowded homes all the real benefits of the pine woods, so that those victims of bronchitis, consumption, asthma, colds and other throat and chest affec- tions, who could not go to pine woods, should have the pine woods and the rich pine air brought to them into the very rooms in which they dwell. A novel tablet, containing the richest pine extracts that is, with all the best pine essences and odours held captive in them was eventually perfected ; and these tablets, or Peps, as they are called, undoubtedly supply a long-felt want in the family medicine cupboard. The need is one that has never yet been properly met by any of the cough mixtures, lozenges, jujubes, and gums, which no medical attendant can con- scientiously recommend, chiefly through the pernicious drug habits they encourage and their sheer inability to grant real, lasting relief. " A Pine Forest in every Home " aptly and pithily describes this new remedy. . . As a Household Medicine they are of unequalled service in cases of Colds, Coughs, Bronchitis, Sore or Relaxed Throat, Huskiness. Loss of Voice, Asthma, Influenza, Pneumonia, Pleurisy, the Hacking Cough of 74 Consumption, Lung Weakness, Children's Colds, Whooping Cough, Croup, Chill or Tightness of the Chest, that old Breathing Difficulty, as well aa for many cases of Headache, Flatulence and Indigestion. For Clergymen, Lawyers, Teachers, and all Public Speakers, they are an invaluable boon. The lozenges had an average weight of 21 grains. The taste and odour did not suggest pine oil, but peppermint with a trace of anise, and on distilling out the oils it was evident that the principal one present was oil of peppermint, but the quantity was far too small to be determined quantitatively. Resinous matter was only present to the extent of 0.7 per cent., and this did not show the characters of pine resin. No alkaloid was found, showing the absence of preparations of both opium and ipecacuanha. Extract of liquorice was present in rather con- siderable quantity, as was proved by extraction of the glycyr- rhizin. Sugars constituted about 75 per cent, of the tablet, but a little of this would be derived from the extract of liquorice; probably 70 per cent, would about represent the sugar added ae such. Talc was present to the extent of about 4 per cent., and was doubtless added as a lubricant to aid in making the lozenges by compression. No other ingredient was found beyond those named ; some sort of pine extract might have been present if it were free from resin or oil, but in that case it could not be expected to possess much medicinal value. The results of the analysis may be thus summarised : Sugar about 70 per cent. Extract of liquorice about 25 Resinous matter 0.7 Oil of peppermint trace. Oil of anise ,, Talc ... ... about 4 BROWN'S BRONCHIAL TROCHES. These are supplied by a firm in Boston, U.S.A. A Is. l^d. box was found to contain forty-eight lozenges. In a circular enclosed in the package it is stated that : " Brown's Bronchial Troches " or Cough Lozenges, allay irritation which induces coughing, giving instant relief in Consumptive, Bronchial, and Asthmatic complaints. "BROWN'S BRONCHIAL TROCHES" were first introduced in the year 1850. It has been proved that they are the best article before the public for Coughs, Colds, Bronchitis, Asthma, Catarrh, the Hacking Cough of Consumption, and numerous affections of the Throat, giving immediate relief. . . . 75 The Trochee are efficacious for children with Whooping Cough, or other affections of the chest, having a soothing influence, assisting expectoration, and preventing the accumulation of phlegm, which causes the sense of suffocation so common with this disorder. There are no particular directions to be observed in the use of the Bronchial Troches. One or two should be allowed to dissolve slowly in the mouth, repeating when necessary. We have seen instances of their good effects in cases of inflammation of the Bronchial Tubes and the hoarse- ness of children. The lozenges had an average weight of 11.3 grains. Chemical analysis and microscopical examination showed the presence of powdered cubeb (about 6 per cent.), extract of liquorice in small quantity, gum, and sugar (about 70 per cent.). No other sub- stance was found; if a little extract of cubeb were present as well as the powdered drug, it could not have been detected with certainty. DR. WHITE'S KOMPO. This is supplied by a firm in Yorkshire in bottles at Is. l|d. and 2s. 9d. A 2s. 9d. bottle was found to contain 11 fluid ounces. It is stated in an advertisement that : Dr. White's " Kompo " is the best-known remedy for Colds, Influenza, Sore Throat* , etc. with other similar statements. But a wider application is claimed on the label, in the following words : A Valuable Remedy for Colds, Influenza, Diarrhoaa, Pains in the Stomach and Bowels, Disordered Stomach, Headache, Cold Feet, Cold Sweats, Bad Circulation of the Blood, Sore Throat, Quinsy, etc. As a Pure Stimulant it is far better than Brandy, or any other Intoxi- cating Drink. The dose is given as One or two teaspoonfuls in a cupful of warm water, well sweetened, several times a day. The bottle contained a brown, somewhat turbid liquid, smell- ing of cloves and cinnamon. Analysis showed it to contain 6.42 per cent, by volume of alcohol, and only 2.4 per cent, of solid matter; this consisted largely of a tannic acid resembling that of red gum. No alkaloid was present, but constituents of capsicum, cinnamon, and cloves were recognised, and a small proportion (0.07 per cent.) of salicylic acid was found. The 76 following formula gave a mixture scarcely distinguishable from the original by either physical or chemical means : Eucalyptus gum (red gum) 1.5 part. Caustic soda 0.08 ,, Oil of cinnamon (or cassia) 0.25 ,, Oil of cloves 0.25 Tincture of capsicum 7.5 parts. Salicylic acid 0.07 part. Rectified spirit 1.5 Decoction of cinnamon and cloves to 100 parts by measure. The decoction was made by boiling 5 parts each of cloves and cinnamon with 200 of water until the volume was reduced by half, straining and adjusting the volume to 100 by measure. The caustic soda in the above formula was used to darken the colour of the red gum. A similar result may be obtained by adding a very little burnt sugar, and there were some indica- tions of the presence of this in the original. The estimated cost of the ingredients for 11 fluid ounces is about 6d. GLYKALINE. This is a liquid supplied by a London firm of L-Mnoeopathic chemists. A Is. ld. bottle was found to contain about 1| fluid drachms. It is described in an advertisement as : A Sure Cure for all Coughs, Colds, Catarrhs, Hay Fever, Influenza, Asthma, Bronchitis, etc. Rapid and reliable in its effects. Checks a slight, cold with one dose. Cures a severe cold in 24 hours. And in a circular enclosed in the package it is stated that : There is no medicine to equal it for promptly relieving those distressing colds where there is a constant flow of a thin watery discharge from the nose, accompanied by continual sneezing, throbbing of the head, and smart- ing pains in the eyes, etc. a few hours sufficing to overcome al] these unpleasant systems. The dose is given on the label as: Three drops every hour in a tablespoonful of water until relieved, then every two or three hours until quite well. Children under five years, a third of the above quantity. Analysis showed the liquid to contain 35 per cent, by volume of alcohol, but only 0.15 per cent, of solid matter. This con- sisted partly of potassium iodide and partly of organic matter. Not the slightest trace of any alkaloid could be found. 77 Each dose would contain approximately 1-350 grain of potas- sium iodide, with a trace of organic matter, which may be derived from some drug. The cost of the preparation is practically that of the alcohol which it contains, or about |d. for the contents of the bottle. LIQUFRUTA MEDICA. The preparation sold under this name is supplied from '' The Liqufruta Laboratory." There appear to be two varieties of the medicine, the one being called simply " Liqufruta," and described on the label as " cure for consumption cough, whooping and every other cough," while the other is called " Liqufruta Medica," and is described on the label as " The Great Consump- tion Cure." The price of the latter is 2s. 9d., and the bottle was found to contain 12A fluid ounces. Other particulars given on the label are as follows : Liqufruta Medica the Only Safe Cure for Pulmonary Consumption, Chronic Asthma, Bronchitis, Catarrh. Certain of the germicidal constituents contained in this remedy are other- wise unobtainable throughout the world. Guaranteed free of poison, laudanum, copper solution, cocaine, morphia, opium, chloral, calomel, paregoric, narcotics, or preservatives. . . . Liqufruta Medica heals the chest, lungs, and throat, arrests the inflam- mation, loosens the phlegm, and effectually destroys the bacilli of con- sumption, etc., which no other medicine can reach. Whilst the cough will be eased at once, the expectoration will be more profuse for a short time. Directions. One dessertspoonful every two hours ; in severe cases every hour, and also during the night whenever cough is troublesome ; take a dose when getting into bed and the moment of awakening in the morning. When symptoms moderate and pronounced benefit has been obtained the doses may be administered with one and a-haif to two hours' interval if desired. The mixture was found to be a dark brown, rat, liquid, smelling like a mixture of garlic or onion and mint. On distilling, a trace of volatile oil was obtain* distillate closely resembling the liquid obtained by di ^ onion and a trace of oil of peppermint with water; 100 parts by measure of the mixture contained 10.05 parts of solids; of these, 2.05 parts were of mucilaginous or pectinous nature, 3.44 parts were glucose, and 2.28 parts were cane sugar. A decoction of onion was found to contain a mucilaginous sub- stance somewhat similar to that obtained from the mixture. 78 The liquid was acid, and on evaporation and ignition yielded an ash which was alkaline, the acidity before and the alkalinity after ignition being approximately equivalent. This is charac- teristic of acid salts containing an alkali-metal and an organic acid, such as potassium bitartrate. The ash contained a con- siderable proportion of potassium, but in the presence of the sugars and vegetable extractive the small quantity of tartaric acid could not be identified ; the acidity and alkalinity indicated 0.4 part (in 100 fluid parts) of potassium bitartrate, accounting for 0.16 part of ash; the total ash was 0.4 part, and the other constituents were such as are found in the ash of most vegetable extracts. Alkaloidal matter was present in very small quantity, the amount being about 0.01 per cent. ; this consisted of two (or more) alkaloids, neither of which gave the reactions of any of the ordinary medicinal alkaloids. The other constituents con- sisted of tannin, a trace of resin, and extractive. The original liquid had a very slightly pungent taste, such as would be given by a trace of a preparation of capsicum or ginger. The results of the analysis thus showed: Oil of peppermint Oil of onion, or garlic [traces Alkaloids I Potassium bitartrate 0.4 part Glucose 3.44 parta Cane sugar 2.28 Mucilaginous matter 2.05 Tannin ,. Exfcractive [together 1.9 Besin ) Water ^ to 100 parts by measure No alcohol was present, and no metallic salts beyond the traces ordinarily accompanying plant extracts. "Examination of the plain Liqufruta (for cough) did not show any important differences between it and " Liqufruta Medica." HYOMEI. The preparation sold under the name Hyomei is supplied by a firm in London. The price of an " outfit " is 2s. 6d., and this consists of an inhaler (consisting of a vulcanite tube), \ fluid 79 ounce of inhalant, with pieces of gauze and a dropper ; a 3s. 9d. " refill " of the inhalant alone was found to contain 2 fluid Hyomei has been widely advertised in the Press for some time past, advertisements 'in the daily newspapers usually occupying a column or so. The following is the first paragraph of one of these: Mr. K. T. Booth, who issues the following announcement, is the world- famous temperance orator, who some years ago, in co-operation with such friends and co-workers as the late Rev. C. H. Spurgeon, Rev. F. B. Meyer, and the late Rev. Newman Hall, Archdeacon Wilberforce, Lord Mount Temple, and others, founded the Blue Ribbon Army, which ultimately led a million to temperance. This glorious work was cut short by acute catarrh and threatened consumption, which sent him, by the order of the late Sir Andrew Clark, health-seeking to Australia. There he made his great discovery of Hyomei (pronounced Hi-o-me), which not only cured him, but has since cured multitudes of other sufferers. Hyomei is an inhalant which, being a powerful germicide, cures by just breathing it. In a booklet enclosed in the package it is thus described : Hyomei, the new Australian Dry-Air Treatment for the Cure of Asthma, Bronchitis, Catarrh, Catarrhal Deafness, Coughs, Rose Colds, Whooping Cough, Colds, Croup and Consumption. The only Natural Method of Cure. The First and only Treatment for all Diseases of the Air Passages and Lungs ever Endorsed by the Medical Profession. . . . What " Hyomei " Is. Hyomei is a vegetable compound the result of recent scientific research. It is a powerful germicide, and absolute destroyer of the germs which cause diseases of the respiratory organs. Hyomei is a cure given by a new method the only treatment through which the diseased parts of the head, throat, and lungs can be reached. What " Hyomei " Does. Hyomei cures all diseases of the ir passages. Cures them by just breathing; cures them through the air you breathe, impregnated with Nature's own antiseptic. No douches, sprays, atomizers, or stomach medicines are used. It at once kills the bacilli of catarrh, bronchitis, con- sumption, asthma, and hay fever, bringing a complete cure that can be obtained in no other way. Another circular enclosed in the package is in the form of a letter, beginning " Dear Friend." From the heading of the paper it appears that the company are the proprietors of "Hyomei," "Hyomei Balm, the wonderful ointment," " Hyomei Skin Soap, a medicated toilet soap," and " Hyomei 80 Catarmel, for catarrh and catarrhal deafness." The letter invites correspondence, as follows : . . if you are a sufferer from any breathing trouble or from any form of skin trouble I can help you. That is why I here invite you to write me personally a letter telling me of your ailment, how long you have had it, and what you have done so far to cure it. Then I will consider your case from the particulars you give me, and if suitable for my treat- ment, will, without charging you any fee, send you a letter telling you what you must do to get your cure, and at the same time will send you sufficient of what I recommend