RL 780 UC-NRLF 172 BY JOHN P. TURNER.M.D. RINGWORM AND ITS SUCCESSFUL TREATMENT BY JOHN P. TURNER, M.D. MEDICAL INSPECTOR OF PUBLIC SCHOOLS, PHILADELPHIA, PA. ILLUSTRATED BY EIGHT HALF-TONE ENGRAVINGS PHILADELPHIA F. A. DAVIS COMPANY, PUBLISHERS 1921 BIOLOGY COPYRIGHT, NOVEMBER, 1921 BY F. A. DAVIS COMPANY Copyright, Great Britain. All Rights Reserved PRESS OF F. A. DAVIS COMPANY PHILADELPHIA. U.S.A. IN MEMORY OF MY FATHER JESSE E. TURNER 500626 INTRODUCTION. IT gives me pleasure to state that the treatment of ringworm of the scalp devised by Dr. John P. Turner has proven remark- ably efficacious in his hands. In the year 1913 the Reynolds Public School, Philadelphia, with a population of six hundred children was badly infested with ringworm. About eighty cases were discovered, of which at least one- half were ringworm of the scalp. In view of the obstinate nature of the latter affection, the proper conduct of the school was a serious problem. Dr. Turner consented to undertake the treatment of these cases in connection with his work as school medical inspector and effected a complete cure a remarkable achievement deserving of medical notice. WALTER S. CORNELL, M.D. Director Medical Inspection of Public Schools of Philadelphia, Penna. (5) FOREWORD. THE author offers this treatise be- cause of the prevalence of ringworm, and because of the success obtained with thousands of cases that have come un- der his care. For over one hundred years this disease has been studied and various treatments advocated. Wherever num- bers of school children are found, ring- worm is most apt to be present. A neg- lected case in a classroom is liable to spread until many cases are found in the school building. The personal appear- ance of the child is interfered with by the presence of this malady, and in ad- dition there is the discomfort it causes by itching and scaling. The treatment (7) Foreword. used by the writer is simple, easy of ap- plication and inexpensive. Any parent or guardian can apply it. Many cases of ringworm, especially of the scalp, are obstinate to most treatments. Usu- ally ringworm is neglected. In order to obtain results, daily treatments must be systematically given. Many children have ringworm of the scalp, and the parents are unaware of its presence until it has developed sufficiently to be very obstinate to ordinary treatment. As soon as the smallest patch or ring is noticed, if instructions given in the Chapter on Treatment are followed, a speedy cure may be expected. In chronic and severe cases, the rapidity with which results are obtained is most remarkable. The treatment to be described has been used by the author for nearly ten Foreword. years. When originated, he had under his care the pupils of a school where existed eighty severe cases of ringworm of the scalp and face. In order to check the rapidly spreading disease, immediate and drastic steps had to be taken. The result was the working out of what is to be given in the Chapter on Treatment. Before describing the remedies used, we shall discuss the history of ring- worm, its diagnosis, differential diagno- sis, and pathology. J. P. T. CONTENTS. I. THE HISTORY OF RINGWORM 15 II. THE PATHOLOGY OF RINGWORM 18 III. THE DIAGNOSIS OF RINGWORM 24 IV. THE DIFFERENTIAL DIAGNOSIS OF RINGWORM 40 V. How RINGWORM is SPREAD 52 VI. THE TREATMENT OF RINGWORM 54 VII. WHEN is RINGWORM CURED? . . 58 ILLUSTRATIONS. 1. How a ringworm grows 21 2. Ringworm of scalp 25 3. Ringworm 1 of scalp 29 4. Ringworm of the face 33 5. Ringworm of the hand 37 6. Ringworm of scalp 41 7. Ringworm of scalp. Diffuse case 45 8. Ringworm of scalp 49 (13) CHAPTER I. THE HISTORY OF RINGWORM. THIS affection was first described by Willan, in 1817, and Plumbe, in 1821. At that time, however, it was not under- stood. It was confounded with alopecia, eczema, and seborrhea. Credit is given to Gruby, of Paris, in 1843, f r discovery of a fungus in the broken off hairs of ringworm areas. To this fungus he gave the name of Microsporon aitdouini. Un- fortunately he called the disease "Porrigo Decalvans." This term had already been used by Bateman in describing alopecia areata. As a result, for a long time there was a confusion between these two con- ditions. Later on Sabouraud (1894), (15) ' 1.6 History of Ringworm. through his discoveries, cleared up these misunderstandings. The fungus of ring- worm was named Trichophyton tonsurans by Malmsten in Stockholm, in 1845. F r ~ merly it was believed all varieties of ring- worm were due to this one distinct species of fungus. Now it is known there are various fungi causing the different forms of the disease. In 1894 Sabouraud published a work on the nature of the Tinea, in which he divided the Tinea tonsurans into two distinct groups : (A) Tinea with small pores (which is due to the fungus called Micro- sporon audouini). (B) Tinea with large spores (due to various forms of the Tricho- megalosporon). History of Ringworm. 17 The small spore Tinea is the common form of ringworm, the large spore the rarer form. Fifty years ago ringworm was very prevalent in England. School children in large numbers w r ere sufferers. CHAPTER II. THE PATHOLOGY OF RINGWORM. THE pathology of ringworm is that of a specific inflammation. The skin is altered in color, due to congestion, al- tered in sensation, due to the effect of the foreign substance produced by the fungus, anxl altered in the size of the part affected, due to enlargement of the blood-vessels. There is present a des- quamation of the skin, and sometimes there is a serous or purulent discharge with crust and scab formation. The eruption caused by the fungus is super- ficial, leaving no permanent destruction of the upper or deeper layers of the skin. (18) Pathology of Ringworm. 19 THE FUNGUS. The fungus consists of branching hollow tubes called mycelium, and of spores. These spores may grow into mycelium tubes. The transition is formed by a protrusion in the cell wall and then by an increase in this projec- tion. In ringworm of the body, the my- celium is large and abundant. INVASION OF THE HAIRS. The view confirmed by Balzer in 1883, and substantiated by many since, is that the mycelium enters the orifice of the hair follicle, insinuates itself between the hair shaft and inner root sheath, and passing down till it reaches the softer cells of the bulb, enters the hair. It then multiplies and ramifies between the fibres of the hair. However, it is possibly best that 20 Pathology of Ringworm. no given rule be laid down as to where the fungus first attacks the hair. It is always in the follicular portion and often toward the root end, but sometimes in one place and sometimes in another. The fungus rapidly grows in and on the hairs, rendering them lustreless, opaque and brittle. They therefore easily break off near the surface of the scalp forming the so-called "stumps." The fungus does not flourish in living tissue. It is not found beyond the epidermic strata. ACTION OF THE FUNGUS. When brought into contact with the skin it passes between the superficial cells of the epidermis and finds its way into the deeper layers. Here it develops and causes an inflammation, forming first a ring of small papules, followed by ves- Fig. 1. How a ringworm grows. Highly magnified. (21) Pathology of Ringworm. 23 icles and possibly crusts. As the ring spreads, the hyperemia in the center dis- appears and desquamation follows (Fig. i). If the scalp is involved and the fungus is the one that causes Tinea ton- surans, the hairs are quickly involved, causing the characteristic scaling patches with the broken off stumps of hairs showing in the affected area. CHAPTER III. THE DIAGNOSIS OF RINGWORM. As it relates to school children, there are two varieties of ringworm. Ring- worm of the scalp (Tinea tonsurans) (Fig. 2) and ringworm of the body (Tinea circinata) (Fig. 4). Ringworm of the inner thighs and perineum (Tinea cruris) need not be considered in the case of children. RINGWORM OF THE SCALP. This form of the disease attacks chil- dren almost exclusively, being hardly ever seen in an adult. It is first noticed as a pea-sized scaly patch. It may en- large to the size of a silver dollar 'or even larger. There may be one or more (24) Fig. 2. Ringworm of scalp. Tinea tonsurans. After Schamberg. (25) Diagnosis of Ringworm. 27 of these patches, or the entire scalp may be involved. When fully developed the patches are usually circular in out- line, slightly elevated above the normal surface, covered with scales, and some- times have a number of little follicular elevations. Over the diseased area are found ends of broken off hairs. The color of the patches varies according to the complexion of the patient. In darker skins they are grayish or slate color, while on white children they are inclined to be more of a pinkish hue. The diag- nosis of ringworm of the scalp is not difficult, although there are a few con- ditions that are at times confused with it. The most important point to remem- ber is the existence of scaling patches with broken off hairs projecting here and there (Fig. 3). A magnifying glass will 28 Diagnosis of Ringworm. readily reveal this condition in case it is not possible to see it with the naked eye. If there is any doubt, the use of the microscope will settle the matter. The presence of the fungus will clinch the diagnosis of ringworm. KERION. (Pustular Ringworm of Scalp.) This form of ringworm arises when deep folliculitis occurs. The patch swells up and appears as a subcutaneous ab- scess. The disease embodies one or more patches which are red, tender, semi-fluctuant, soft and swollen. Many of the hairs come out while a few may remain for a time. These are easily pulled out without the usual breaking off. They are loosened by the exudate formation. Fig. 3. Ringworm of scalp. Tinea tonsurans. (29) Diagnosis of Ringworm. 31 While Kerion presents a worse pic- ture, it will cure itself quicker than ordi- nary Tinea tonsurans. The reason is, that after a time the hairs over the patch all come out, the inflammation subsides and new hairs grow. We are not troubled with the stumps. STUMPS. A distinction must be made between healthy short hairs and stumps. The term "stumps" should be restricted to diseased short hairs about an eighth or a quarter of an inch long, broken off near the surface of the skin. They are swollen, lustreless and usually break off when the attempt is made to pull them out. The reason they are so fragile is because they are impregnated with fungi. In chronic cases, stumps are sometimes 32 Diagnosis of Ringworm. difficult to find. They may be hidden among the long hairs, .on a patch, or under a scab. At other times the stumps may be found lying close on the surface of the skin, sometimes glued to the scalp with a sticky sebaceous matter. HOW TO PREPARE THE SLIDE. Pull out two or three of the broken off hairs and place on a slide with a drop of liquor potassae (a forty per cent, solu- tion of caustic potash). Permit this to stand for fifteen minutes, then under a power of two hundred and fifty diam- eters the fungus and the lesion of the hair will be visible. RINGWORM OF THE BODY. This form of ringworm is most often found on the face (Fig. 4). It is char- Fig. 4. Ringworm of the face. Tinea circlnata. After Schamberg. (33) Diagnosis of Ringworm. 35 acterized by the presence of rounded sharply circumscribed, pinkish or gray- ish scaly patches. These areas often clear up in the center causing a ring- like formation. The affected part is raised above the surrounding skin. It sometimes itches. The presence of the fungus determines the diagnosis. The examination of a specimen under the microscope is made as follows : Scrape a few of the scales with a knife blade and place upon a slide, containing a drop of liquor potassae. Over this place a thin glass cover. Press the cover down and permit the specimen to remain for a few minutes. The fungus will be detected here and there. Sometimes brothers and sisters in a family with one obstinate case of ring- worm remain free from the complaint. 36 Diagnosis of Ringworm. In some children the fungus takes but slight hold and is easily destroyed. In others the disease takes rapid hold and 3preads quickly. The state of the soil (skin) has much to do with the growth of the fungus. Many writers contend there must be present some constitu- tional ailment, lowering the natural re- sistance, in order for the fungus of ring- worm to gain lodgement and grow. It has been observed by some that children of pallid, sickly natures are the most sus- ceptible victims. Malcolm Morris wrote in 1 88 1 that children with golden or colorless hair, with gray or blue eyes, and with a very fine skin, were the most often affected. In the experience of the writer, this is not true. In this country, among Caucasians, the more swarthily complexioned seem to be the greater Fig. 5. Ringworm of the hand. Tinea circinata. After Schamberg. (37) Diagnosis of Ringworm. 39 sufferers; while Negro children furnish the richest soil for the development and growth of ringworm. Three-fourths of the number of cases of this disease re- ported to the Bureau of Health in Phil- adelphia during the past year, were from Negro children. It is also the experience of the writer that robust, and to all ap- pearances healthy children, have ring- worm as violently as the ill nourished. There seems to be a certain condition present in the skin, the nature of which is obscure, which invites the growth of the germ. CHAPTER IV. THE DIFFERENTIAL DIAGNOSIS OF RINGWORM. IN order to be able to discriminate between this affection and those condi- tions that might be confused with it, we shall discuss briefly a few of them. SIMPLE ECZEMA OF THE SCALP. This disease is attended with consid- erably more itching. It is usually spread over a larger area, and not limited to well defined patches. The broken off hairs, which are characteristic of ring- worm, are not present. The hairs of ringworm are easily pulled out while in eczema they are as a rule firmly im- bedded. (40) Fig. 6. Ringworm of scalp. Tinea tonsurans. (41) Differential Diagnosis of Ringworm. 43 PEDICULOSIS CAPITIS. (Head Lice.) Itching is one of the chief symptoms. It is found mainly on the back of the head. Inflamed patches are present on which are found signs of scratching. The patches are small and the hairs are matted and moist. There is an absence of stumps of hairs. The presence of pediculi confirm the diagnosis. SEBORRHEA CAPITIS. (Dandruff.) Dandruff is a condition caused by an excessive secretion of sebum. The hairs are matted together. The scales are smaller and much greater in number than those found in ringworm. They stick to the skin which is not inflamed. 44 Differential Diagnosis of Ringworm. PSORIASIS CAPITIS. This disease occurs in small or large patches. It runs a chronic course. The scales on the patches are thicker than in ringworm. Usually there is a history of psoriasis on other parts of the body. The hairs on the scalp are found to be growing unbroken in the patch. ALOPECIA AREATA. (Baldness in Areas.) This is the affection with which ring- worm is most often confused. The diag- nosis between the two is usually not diffi- cult. In alopecia areata there is an ab- sence of scales and stumps over the bald spot. Around the margin of the bald- ness we often find short stumps of hair. These should not be confused with those of ringworm, as they are all broken off Fig. 7. Ringworm of scalp. Tinea tonsurans. Diffuse case. (45) Differential Diagnosis of Ringworm. 47 on a level with the skin. The micro- scope will settle the diagnosis if in doubt. IMPETIGO CONTAGIOSA. This disease is characterized by the formation of discrete flat vesicles which turn rapidly to pustules and then form crusts. It is highly contagious. The vesicles range in size from a pin head to a pea or even larger. There are present no stumps of hairs as in ringworm. Im- petigo appears on either the scalp or body. Aldersmith writes concerning this disease : "Impetigo is sometimes thought to be ringworm. The rapidly spreading form of pustular ringworm (Kerion) closely simulates Impetigo contagiosa." Impetigo is common in the occipital region of the scalp. This is especially true when complicated with pediculosis. 48 Differential Diagnosis of Ringworm. Some writers regard as the cause of im- petigo a particular fungus, while others contend micrococci are the root of the trouble. A microscopical examination will determine the presence or absence of ringworm if in doubt. Impetigo does not spread in schools as does ringworm. It is found often in several members of the same family. SYPHILITIC ERUPTIONS. Many of these may resemble Tinea circinata. Itching is not present and as a rule the eruption is more symmetrical. The history will aid in diagnosis. HERPES IRIS. In this condition we find a number of vesicles and papules. Often the vesicles are arranged so as to form distinct Fig. 8. Ringworm of scalp. Tinea tonsurans. (49) Differential Diagnosis of Ringworm. 51 rings. When one ring is fully formed, another sometimes forms around it. If in doubt, the microscope will determine. ERYTHEMA CIRCINATUM. This and other varieties of erythema are often mistaken for Tinea circinata. Erythematous patches are often symmet- rical. They have well defined edges, which are raised and thickened. CHAPTER V. How RINGWORM is SPREAD. RINGWORM is spread through simple contact. Hairdresser's and barber's tools are not infrequent conveyers. The fungus may be carried from one child to another by towels, brushes and other utensils used in common;. Often ring- worm exists in a child's head unknown to its parents. Such a child is a source of contagion to its playmates. Children in play often pass their hands through each others' hair, put on each others' hats or rub their heads together. Adults not infrequently contract ringworm of the body by handling and treating ring- (52) How Ringworm is Spread. 53 worm of the scalp. It is quite possible the disease is spread by the promiscuous piling together of wraps and hats in a school closet. CHAPTER VI. THE TREATMENT OF RINGWORM OF THE SCALP AND BODY. THE SCALP. IN severe cases, have all the hair cut close. If there is only one isolated patch, cut the hair close, the radius of an inch all around the area involved. The treat- ment consists of four stages each occupy- ing a few days, then a repetition if neces- sary. First Stage: (Daily for four days.) Scrub the scalp or patch with castile soap and warm water. Then apply with a cotton probe, tincture of iodine. (54) Treatment of Ringworm. 55 Second Stage: (Daily for three days.) Following the scrubbing, rub into the parts thoroughly oil of cade. Third Stage: (Daily for three days.) Following the scrubbing apply, by rubbing into the parts, ammoniated mer- cury ointment 20 per cent, strength. Fourth Stage: (Daily for three days.) Following the scrubbing, rub into the parts resorcin ointment 20 per cent, strength. Continue the treatment if necessary by beginning all over and going through the same routine until cured. Mild cases will yield readily, and the most obstinate 56 Treatment of Ringworm. will soon show signs of improvement. From one to fifteen courses of treatment will be necessary. Few cases fail to yield to four courses of treatment. THE BODY. There are two stages: First Stage: (Daily for three days.) After thoroughly scrubbing the af- fected area with castile soap and warm water, paint over the part with tincture of iodine. In case the ringworm is on the face it is well to use colorless iodine. Second Stage: After cleansing with castile soap and warm water, rub into the parts ammoni- ated mercury ointment 20 per cent, strength. Treatment of Ringworm. 57 Continue the treatment until the ring- worm disappears. This will require from one to four courses of treatment. CHAPTER VII. WHEN is RINGWORM CURED? THIS question is often asked, particu- larly in reference to the return to school of children who have been suffering with the disease. THE SCALP. Ringworm of the scalp cannot be said to be cured until the entire scalp is care- fully examined with a magnifying glass to ascertain if there are any stumps of hair present. Absence of the fungus upon microscopic examination is an im- portant determining factor. Hair may be growing over the form- erly bald spot, but if the broken off hairs are found, the case is not cured. (58) When is Ringworm Cured? 59 THE BODY. A patient with Tinea circinata cannot be pronounced cured until the margins of the patch are free from all papules and desquamation. The area should no longer be raised above the surrounding surface. If there is doubt, the skin just inside the margin of the patch should be scraped and examined under the microscope for the presence of the fungus. If found the .case is not cured. Sometimes we are unable to find any fungi in the specimen, yet the disease is still present. Stop all treatment and watch for a recurrence of papules and scales. DOES ONE ATTACK RENDER IMMUNITY AGAINST ANOTHER? Many people are under the false im- pression that one attack of ringworm 60- When is Ringworm Cured? gives the child an immunity against fur- ther attacks. Even after new healthy hair has grown on a previous patch, the disease has been known to commence again on the old spot. In most of such cases, the old attack was never properly cured; the next infection starting from the stumps that had been quiescent. SOME CHARACTERISTICS OF RINGWORM. It is contagious. It is more prevalent among boys than girls. Found more frequently among Negro children than among white. Its presence gives an objectionable appearance whether on the face or scalp. Ringworm of the scalp if neglected When is Ringworm Cured? 61 will form layers of scales, which peel off. If through neglect or otherwise, ring- worm persists through childhood, it dis- appears when the child reaches the age of fifteen or sixteen. There appears to be some unexplained change in the skin, as a soil for the growth of the germ at that period of life. SOME DON'TS IN THE CARE OF RING- WORM CASES. Don't neglect a case no matter how trivial in appearance. Don't place on the head the hat or cap of another suffering with ringworm. Don't allow the use of a towel or other article that has been in contact with ringworm. 62 When is Ringworm Cured? Don't fail to wear a skull cap if a scaling ringworm of the scalp exists. Don't apply vaseline or grease to ring- worm patches for the sake of hiding them. These applications have no cura- tive effect. Don't permit the hair to grow long if ringworm is present. 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