MM THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES PUBLIC HEALTH, WORKS BY THE SAME AUTHOR. Principles of Forensic Medicine. By William A. Guy, M.B. Cantab., F.R.S., Professor of Forensic Medicine in King's College, London. Third Edition, Revised, Enlarged, and copiously Illustrated by Wood Engra\-ing5. In fcap. cloth, price 12s. 6d. Hooper's Physicians' ,Vade Mecum ; a Manual of the Principles and Practice of Physic, with an Outline of General Pathology-, Therapeutics, and Hygiene. With Wood Engravings; revised. By William Augistis Grv, M.B. Cantab., F.R.S., Fellow of the Royal College of Phvsicians and Physician to King's College Hospital, and John Haklev,'M.D. Lond., F.L.S., Fellow of the Royal College of Phy- sicians, Assistant-Physician to the London Fever Hospital. The Eighth Edition, price 12s. 6d. The Case of the Journeymen Bakers. A Lecture on the Evils of Xighrvvork and Long Hours of Labour. Bj- Dr. Guv. Price IS. The Sanitar}^ Condition of the British Army, especially on the Want of Space in Barracks. By Dr. G vv. Price is. WORKS ON SOCIAL SCIENXE. The Original. By Thomas Walker. Contain- ing, in addition to many Essays on subjects of the highest interest, several Papers on Beggars, Paupers, and Poor- Laws, &c. Price 5s. The Evils of England. By a London Physician. Price IS. The Plague of Beggars. A Dissuasive from Indis- criminate Almsgiving. By a London Physician. Third Edition. Price id. Defoe's Giving Alms no Charity, and employing the Poor a Grievance to the Nation. By a London Physician. Price id. The Nuisance of Street Music ; or, a Plea for the sick, the Sensitive, and the Studious. By a London Physician. Price id. Who are the Poor } A cheap Tract for circulation. By a London Physician. Price 2s. per hundred. Dr. Strange on the Seven Sources of Health ; a Manual of all that concerns the Preser\ation of Health and the Prevention of Disease. Fcap. sewed, price 2s. 6d. PUBLIC HEALTH POPULAR INTRODUCTION TO SANITARY SCIENCE. BEING A HISTORY OF THE PREVALENT AND FATAL DISEASES OF THE ENGLISH POPULATION FROM THE EARLIEST TIMES TO THE END OF THE EIGHTEENTH CENTURY. WILLIAM A. GUY, M.B. CANTAB., F.R.S. FELLOW OF THE ROYAL COLLEGE OF PHYSICIANS ; PROFESSOR OF FORENSIC MEDICINE AND HYGIENE IN KING's COLLEGE, LONDON. &C. &C. &C. HENRY RENSHAW, 356, STRAND, LONDON. 1870. [-4// rights of Translation reserved.^ LOKDOX : EATILL, EDWABDS AST) CO., PBDrUBS, CHAXD08 STBMT, COyiST GAEDEX. H FA I TO ROBERT CHEERE, Esquire, MEMBEB OF THE COUlfCIL OF KING'S COLLEGE, LONDON", AND TBEAST7BEB OF king's COLLEGE HOSPITAL. THESE LECTURES AKE DEDICATED AS A TRIBUTE OF SINCERE ESTEEM AND AFFECTIONATE REGARD BY THE AUTHOR. PREFACE. The eight lectures I have so recently delivered at King's College are here printed, somewhat condensed, but other- wise little altered. In compiling them, as in printing them, I have been actuated by the belief that tlie Science of Hygiene is imperfectly appreciated, because some are ignorant, others unmindful, of the rich benefits it has lavished upon us in times past. I have accordingly endeavoured to remove the existing ignorance or indifference by submitting the facts of the case in such a form that they may commend themselves to the members of my own profession as true and yet not trite j to the public as interesting in themselves,, and supremely important in their practical applications. The title I have adopted indicates of itself the wish by which I have been actuated to combine a scientific with a popular treatment of my subject. Whether I have suc- ceeded in so difficult an undertaking must be left to the judgment of others. In treating my subject after the historic method, I wish it to be understood that I have chosen rather to present a connected series of faithful abstracts of the chief works of our great sanitary historians and reformers, with facts and viii Preface. figures taken direct from the London Bills of Mortality, than to settle disputed questions by weighing one authority against another. I must also state that, in omitting minute references to authorities, I have been solely influenced by the wish to fit my work for continuous uninterrupted reading. Nevertheless I believe that the chief sources of the information I have brought together and condensed will be found sufficiently indicated for every useful purpose. If I may be allowed to commend one lecture rather than another to the attention of philanthropists and states- men, it is the seventh, in which, as I believe, I have rightly estimated the character and works of John Howard. Let me add that, for the reasons assigned, I have wished to place in the hands of the public a cheap and attractive volume j and that in that wish I have been well seconded both by publisher and printer. 26, Gordon Street, May, 1870. CONTENTS. LECTURE I. Sanitary Retrospect, i. Social and Political Consequences ot Fatal Epidemics, 4. Aim and Scope of Sanitary Science, 5. Sources of Knowledge, 6. Scientific Methods, 7. Numerical Method, 8. Illustrations — Devonshire Colic, 9. Overcrowding and Madness, 12. Hot and Cold Regimens in Small-Pox, 16. Extempore Hospitals, 18. Saving of Infant Life in the Eighteenth Century, 19. Scourges of the Adult Population — Scurvy, Jail-Fever, and Small- Pox, 21. Labours of Baker, Cook, Howard, and Jenner, 25. The Future of Hygiene, 26. LECTURE n. Sanitary Epochs, 28. Health and Disease, 29. Cost of Disease, 30. Variable Character of all the Elements that afiect Health, 31. Causes of Death, 32. Scrofula, ^^. Consumption, 34. Zymotic Maladies, 35. Epidemics — meaning of the term, 36. Varieties of Epidemics, 37. Cholera, 39. Scarlatina, 41. Cholera and Plague, 43. Bronchitis, 44. Ancient Famines and Pestilences, 46. The Black Death of the Fourteenth Century, 47. Symptoms and Nature, 49. Great Mortality, 50. Consequences and Antecedents^ 51. Preventive Measures, 53. Lazarettos and Quarantine, 54. LECTURE III. Black Death continued, 55. Consequences, Moral and Religious, 56. The Flagellants, 57. Poisoning of Water, and Persecution of the Jews, 58. Habits of the English People — Bad Housing and Gross Feeding, 59. England in the Olden Time, 60. London in the Twelfth Century, 61. Sweating Sickness of the Fifteenth and Six- teenth Centuries, 63. Dr. John Caius, 64. Lord Bacon, 65, b Contents. Nature of the Disease, 66. Sanitary Measures, 68. Medical Treat- ment, 69. Diet of the English, 70. Letters of Erasmus, 71. English Intemperance, 72. The Sweating Sickness, a modified Influenza, 74. Petechial Fever, Brain Fever, Trousse-Galant, Epidemic Flux, Scurvy, and Diphtheria, 76. Atmospheric Dis- turbances, 81. A Sickly Century, 82. LECTURE IV. The Plague of the Sixteenth and Seventeenth Centuries, 8.^. London Bills of Mortality, 84. The Five Epidemics — their Duration and Mortality, 85. Summary of Facts, 85. Deaths in the Plague of 1665, 87. Dr. Nathaniel Hodges — His Account of the Plague of 1665, 89. Plague- water of the College of Physicians, 90, Ravages of the Plague, 91. Its Decline, 92. The Plague at Eyam, 93. Mompesson, 94. Frightful Mortality-, 95. Episodes of the Plague at Eyam, 97. Precursors of the Plague in London, 99. Its Cause — Contagion, 99. Symptoms, 100. Blains, Buboes, and Tokens, 101. Treatment of the Sick, 103. Preventive Measures, 104. Virtues of Sack, 103, and 105. Amulets, Charms, and Alexi- pharmics, and other strange Remedies, 103-106. Hodges' Treat- ment of Himself, 106. Later Attacks of Plague in other Countries ; at Marseilles, Moscow, and Malta, 107, How to deal with the Plague, 108. LECTURE V. Third Sanitary Epoch, from the Fire of London in 1666, to the End of the Eighteenth Centurj-, no. London before the Fire, 112. Re- building of London — Plans of Wren and Evelyn, 113. Effects of the Fire, 115. What it did not do, 116. Sanitary Condition of London during the Seventeenth Centur)-, 117. Sydenham, 119. Small-Pox, Measles, Syphilis, and Scuny, 120. The Cool Regimen, 123. Causes of Death at the Beginning of the Eighteenth Centurv-, as shown by the London Bills of Mortality-, compared with Earlier and Later Returns, 124. Influenza of 1732-3, 128. Sanitary Im- provements, 130. Ventilation in the First Quarter of the Centuiy by Wren, Desaguliers, Sutton, and Hales, 131. Ventilation of the House of Commons, 131. Of Ships, 132. Of Buildings, 134. Sanitary State of the Last Half of the Century, 135. The De- vonshire Colic, the Jail-Distemper, Scur\y, Dysentery, and Small- Pox, the Fatal Diseases of the Eighteenth Century, 136. Contents. xi LECTURE VI. Lead-Colic resumed, Huxham's Account, 137. Requirements of the Eighteenth Century, 139. The Scurvy, 140. Its Prevention and Cure — the Potato, 141. Symptoms of the Disease, 142. Not peculiar to Seamen, 143. The Scurvy on Land, 144. At Quebec, 145. At Millbank, 146. Scurvy in the Navy, 148. State of our Ships-of-War a Century ago, 148. Ravages of the Disease, 149. Miscarriage of Warlike Expeditions, 150. Scurvy Prevented and Cured, 152. Anson's Expedition, 155. Cook's First Voyage, 159. Captains McBride and Parry, 160. Sanitary Reforms in the Navy, 161. Comparative Mortality of Seamen in the Eighteenth and Nine- teenth Centuries, 162. Increased Efficiency of the Navy, 163. Improved Health of the Army, 164. LECTURE VII. The Jail-Fever and John Howard, a Romance of History, 165. Its Early History, 165. Black Assizes at Oxford, Exeter, and London, 166. A Black Assize in Dublin, 172. The Jail-Distemper Spreads among the People, 172. Conveyed in Clothing, 172. Infects our Armies and Fleets, 173. State of English Prisons and Bridewells, in 1774, 174. Wood Street Compter, 174; The King's Bench, 175. County and Borough Jails; Dartford, Cambridge, Marlborough, and Launceston, 176. Deprivation of Water, Air, and Light, 177. Prison Squalor and Deititution, 178. Prisons private Property, 180. Their Owners, Clerical and Lay, 180. Extensive Prevalence of the Disease, 181. The Jail-Distemper in France, 182. The Disease generally a Form of Typhus, 183. Not always the same Disease, 184. Howard's Precursors, 185. Biography of Howard, 186. His Sanitary Improvements at Cardington, 187. Sheriff of Bedford, in 1773, 188. His Prison Inspections, 189. .The Acts of Parliament of 1774, 190. Their immediate Results, 190. What our Prisons now are, 190. Howard's Life and Death — His Character, defended against Himself and others, 191. Howard a Man of Genius, 192. xii Contents. LECTURE VIII. Small-Pox, 19.1. Small-Pox and Plague Compared — Calculations of Blanc and Black, 194, Its Awful Ravages in all Parts of the World, 195. No Respecter of Persons, 196. Its Early History, 197. In Europe in the Sixth Century, 197. Mortality, 198. Mortality in the Army, 199. A Cause of Blindness, 200. Deaths at Different Ages — ver\- Fatal to Children, 200. Inoculation, its History, 201. Introduction into England, 201. Mild Character of the Modified Disease, 202. Successful Inoculators, 203. Estimate of the Value of Inoculation, 204. Its Influence on the Aggregate Mortality by Small- Pox, 205. Small-Poxatthe Closeof the Eighteenth Century, 206. Vaccination and Edward Jenner, 207. Character of his Dis- covery, 208. His Perseverance, and Ultimate Success, 209. What Vaccination is, 209. Its Success as Compared with Inoculation, 210. Numerical Statements of Result?, an. Extirpating Power of Vac- cination — Illustrations, 212. Past Sanitary Progress, 213. Health and Civilization, 214. Sanitary Discoveries of the Eighteenth Century, 215. Grounds for Expecting further Sanitary Improve- ments, 215. The Policies of Palliation and Prevention, 216. LECTURE I. IXTRODUCTORY. The Council of King's College in the exercise, as I think, of a very wise discretion, have determined that henceforth Hygiene, Public Health, Sanitary Science, shall be duly honoured within these walls. They have accordingly founded a Chair of Hygiene ; and have appointed me their first Professor. I am very sensible of the honour ; I re- cognise the responsibility, and I will strive to justify the choice. Need I say that I do not handle this subject now, either as learner or teacher, for the first time. My interest in it dates back more than a quarter of a century. It began at a time when sanitary science, legislation, and organization were in their infancy ; so that if some exotic pestilence (such as the cholera) landed on our shores, or some home- bred epidemic (such as typhus fever) scattered sickness and death among us, we were taken by surprise : we lacked everything needful — legal authority, a centre ofintelligen guidance and control, a staif of officials. But happily, we were not equally destitute of facts; for the Registrar-General had been for some time at work, heaping up materials to serve as the bricks and hewn stones of a scientific edifice, and furnishing periodical returns which had a direct prac- tical value, both through the interest they created and sus- tained, and the wholesome warnings they administered. When I say that, at the time to which I refer, the science of Hygiene was in its infancy, I do not mean to Retrospect. assert that we had no knowledge of preventible causes of disease and premature death, or to ignore all that the eighteenth century had taught us about the lead colic, the scurvy, the jail-distemper, and the small-pox. Nor do I overlook the fact that La Medecine Legale, and L'Hygiene Publique, had been treated by Fodere and otliers as parts of one larger and more comprehensive science in which the State had a special interest 3 that Paris and Fonblanque, in treating of Medical Jurispru- dence, had something to say about the *' preservation of public health," about nuisances, plague-police, and bills of mortality 3 and that we were not without able treatises on such special topics as the influence of employments upon health. But Hygiene had not then grown to the perfect shape and full stature of a science. It was not fully displayed in any treatise, or set forth in any recog- nised and authoritative course of lectures. Again, I do not speak of sanitary^ legislation as^non- existent, but as inefficient. If a neighbour stopped some " antient light" or corrupted the air "with noisome smells," a man had his remedy in an action at law 3 and from very early times, he had a chance once a year of bring- ing some common nuisance under the notice of the Court- leet. But efficient sanitary legislation there was none. And the same may be said of sanitary organization ; for the officer of health was then known only in Ireland, as the legislative offspring of the inquiries of the Select Commit- tee of the House of Commons " On the State of Disease and Condition of the Labouring Poor in Ireland," embo- died in the Reports of 1819. A quarter of a century was to elapse before the "large towns and populous districts'* of England were to be submitted to a like scrutiny, with a like practical result. It was in 1844 that the Commis- sioners appointed to conduct that inquiry presented their first report : and towards that report (monument as it is space and Consiiniption. of the sagacious and well-directed industry of Mr. Edwin Chadwick) I contributed the results of a laborious inquiry into the health of letter-press printers, and of others fol- lowing in-door occupations. This inquir}'- taught me that a great saving of life might be confidently looked for in an unexpected quarter : that out of 36,000 deaths a year in England and Wales, which I attributed to true pulmonary consumption, 5000 might be saved by increased space and improved ventilation in shops, workshops, and fac- tories 3 that among men doing the same work under the same roof, the liability to consumption was determined by the space j and that this might be narrowed to a point at which men would die as fast as by some contagious malady, so that here, as in Italy, consumption might seem to pass from one person to another. Such being the result of my first sanitary inquiry, it was but natural that, without disparaging the art of healing, I should come to think with Fodere, that it is in the power of governments to do more good to mankind than all the books on medicine put together, and be ready to co-operate with those who felt that a "Health of Towns' Associa- tion" ought to spring out of the startling revelations of the " Health of Towns' Commission." Accordingly, from 1845 ^^ ^^4^ (when "The Nuisances Removal and Dis- eases Prevention Act " was passed), by lectures, by speeches, by printed appeals, and by all the legitimate machinery of a wholesome and successful agitation, I bore my part in that labour of love. With the first sanitary Act to show as the fruit of its efforts, the Health of Towns' Association soon died a natural death 5 but the interest which it had excited and sustained did not die out. There were still whole bodies of men and women, such as the London bakers and the needlewomen, suffering grievous physical evils which no existing legislation could alleviate or remove 3 and our soldiers were victims of a sanitary Political Aspect of Plagii^cs. neglect both cruel and costly. There was still, therefore,, a work of wholesome agitation to be carried on j and in this, too, I bore a part. The interval between the eventful year 1848 and the present time has been filled by a series of researches on the Influence ot Occupations on Health, tlie Duration of Life among the higher and middle classes, the Dietaries of Prisoners, the Mortality of Hospitals, the Fluctuations of Mortal Maladies, the Relation of Insanity to Crime, and several other topics directly bearing on the Science and Art of Hygiene. This brief retrospect will not, I trust, be condemned as- egotistic. It was not unnatural, I think, that tlie first occupant of a new Chair should desire to justify the choice which has placed him in so distinguished a position. To these few words which, counting on your indul- gence, I have ventured to say about my own sanitary work, I desire to add, that if at any time during the last quarter of a century — at the beginning of it, when the subject wore the blush of novelty, or, more recently, when that attraction had ceased — I have been impressed with the importance of sanitary science, that feeling has been confirmed and strengthened by every inquiry into which I have been led during the preparation of this course of lectures. Brought, so to speak, into close contact with the great pestilences of tlie Middle Ages — with the Black Death of the fourteenth, the Sweating Sickness of the sixteenth, and the Oriental Plague of the seventeenth century — I found the historians who recount their ravages profoundly impressed with their social and political consequences. Hecker, the learned author of the " Epidemics of tlie Middle Ages," finds in the Black Death '' the greatest impediment to civilization within the memory of man" — " One of the most important events which have prepared the way for the present state of Europe 3" our Professor of Aims of Sanitary Science. Economic Science and Statistics attributes to it nothing short of "an economical revolution" here in England 5 and historians of repute have attributed the decline and fall of the Roman Empire to the pestilences which swept off the adult male population, and left the then proud mistress of the world an easy prey to the barbarians. But these opinions, though they served to confirm my ^rst impressions of the great importance of Sanitary Science, did not take me by surprise, for I called to mind the confident statement of Sir Gilbert Blane, that if the mortality of the British Navy during the war with Ame- rica had obtained throughout the French revolutionary war, our stock of seamen would have been used up, and " men would not have been procurable by any bounties, •however exorbitant." So that it was not the seaman- ship and fighting qualities of our sailors alone that carried lis triumphantly through that terrible contest, but a re- duced mortality due to the sanitary discoveries and reforms which first recruited oar population by saving lives in infancy and childhood, and then cut off from our forces ►by sea and land, the destructive supplies of jail-fever, scurvy, dysentery, and small-pox. I feel, then, that we are dealing with a subject, the im- portance of which it is impossible to deny and difficult to exaggerate. Let us look closely into its aims and scope, the sources of the knowledge it accumulates and applies, the scientific methods it employs, its past triumphs, its future prospects. The aim of Sanitary Science is to prevent disease, pre- serve health, and prolong life — to maintain the whole people in the highest efficiency for the labours of peace or the struggles of war. If we prefer the term Hygiene, we may divide it into two branches — a private hygiene if we address ourselves to individuals, a putlic hygiene if we deal with nations or communities. So? trees of our Knowledge. It is of public hygiene that I am to speak in this course of lectures J and it is a ver}' large and comprehensive science. It has to do with persons of every rank, of both sexes, of every age. It takes cognizance of the places and houses in which they live ; of their occupations and modes of life ; of the food they eat, the water they drink^ the air they. breathe j it follows the child to school, the labourer and artisan into the field, the mine, the factory, the workshop 5 the sick man into the hospital j the pauper into the workhouse 3 the lunatic to the asylum 3 the thief to the prison. It is with the sailor in his ship, the soldier in his barrack ; and it accompanies the emigrant to his new home beyond the seas. To all of these it makes application of a knowledge remarkable for its amount, and the great variety of sources whence it is derived. To physiology and medicine it is indebted for what it knows of health and disease ; it levies large contributions on chemistry, geology, and meteorology j it co-operates with the architect and engineer j its work commends itself to the morahst and divine. The Council of this College have always acknowledged this its moral and religious aspect j and from the first establishment of the Theological Department, have ar- ranged that its pupils should not leave this place ignorant of the fact that the destitution which attracts disease repels religion. Among o\xx sources of hnowledge there are two to which I must make special reference. I mean the past history of disease, and its current history as displayed in the periodical returns of the Registrar-General. Of its history in times past, I may observe that it is in many points of view extremely important. It teaches us that several fatal epidemics, some imported, some bred at home, have ceased to afflict us because we have relinquished the habits of life that welcomed or produced them 5 that some en- Scientific Methods. demic maladies have nearly disappeared with a wider and better cultivation of the soil, and others with the spread of commerce, and the increase in the number and variety of our articles of food 3 while, in one instance at least (I speak of the lead colic), much suffering has been averted, and many lives saved, by inquiries conducted on the soundest principles of induction 3 and in one ever-memo- rable case (vaccination), by closely observing nature, and listening to tlie voice of analogy. These historic retro- spects, full, as they are, of instruction and encourage- ment, cannot be disregarded in any systematic course of teaching. The current history of disease is equally indispensable, not merely as a means of comparison by which the past becomes more instructive, but as indicating, at short in- tervals of time, the exact state of the pubHc health. Nor must we forget that these very reports, so valuable at the time of their publication, are to become, in their turn, materials of history, and standards of comparison indis- pensable in all inquiries into the sanitary state of any class or group of persons, of any village or district, of men or women following any given occupation. And now, having said something of the aim and scope of our science, and something also of our sources of in- formation, I proceed to inquire by what methods of pro- cedure we transmute it into scientific truth ; how we become possessed of those general principles which we hold in reserve, to be applied at a moment's notice to such special cases as may present themselves. To answer this question, we must first inquire to what class of sciences this science of ours belongs. Obviously to the same class as medicine itself. Both are pre-emi- nently sciences of observation, with much in common and many points of contact j both make disease their study, but in different ways. With the physician the TJic Numerical Method. question is. What will cure an ague or mitigate a fever ? with the health officer. What will prevent them? If the physician takes cognizance of prevention, it is only to ad- vise the patient and his household what precautions they should adopt j but the care of the officer of health extends to the whole district or community threatened by the disease. The physician may advise a consumptive patient to abandon some unhealthy occupation, damp dwelling, or undrained district 5 the officer of health would render the occupation healthy, or drain the district dry. Medicine studies climate, in order to learn how it may suit a case of asthma or consumption ; hygiene inquires what effect it is likely to have on a fleet or an army. In a word, while cure or palliation is the aim of medicine, prevention is the object of hygiene 3 while the one studies the good of the unit, the other looks to the welfare of the mass. And this consideration leads us straight to the point at which we are aiming — the natureof our scientific methods. As hygiene deals with mankind not one by one, but in masses, its scientific method can be no other than that numerical method so often confounded with its leading application — statistics. If this word now meant what it originally did, and what, I tliink, it ought still to do — the science of States — then hygiene would take rank among its leading subdivisions as applying the great State- policy of prevention to health and disease. Of this numerical method which the French physician Louis so largely applied, and Gavarret so ably explained and illustrated, I have now to treat, as it lends itself to the science of hygiene, premising that under the mistaken name of statistics it has been the subject of many a pleasant jest, and freely admitting that it is an instru- ment of danger in the hands of the ignorant, tlie awkward, or the careless, though safe and sure in the grasp of the honest and intelligent. Every honest man finds it a friend ; TJic DevonsJiire Colic, to the man who prefers the triumph of an opinion or a party to the truth, to him alone is it an enemy. The precautions to be observed by those who make use of this powerful instrument of research are many, and not always obvious. They do not lie on the surface, but crop up at every turn. With each fresh inquiry they present themselves afresh j with each new science they change their form and character. I will illustrate these precautions and the application of the method as I have found it in the act of giving birth to great hygienic discoveries. Be it, however, well understood that this logic of large numbers is itself subordinate to a universal logical method which deals with sums and averages no otherwise than with in- dividual facts, or with the results of experiment ; indeed with all data, whatever form they assume. So that the instances I am about to adduce must be taken as illustra- tions both of the numerical method and of this more com- prehensive logic. They all belong to the sanitary history of the eighteenth century, and are taken from the works of Sir George Baker, who is not generally numbered among hygienic authorities. I. Quite early in the eighteenth century, certainly prior to the year 1703, there prevailed in the county of Devon a disease of which the first and usual manifestation was a painful colic, the second a paralytic dropping of the hands j while, in rare instances, the sufferers became de- lirious or epileptic, and died at length convulsed or coma- tose. Cases of this disease were so numerous in Devon- shire and so rare elsewhere, that both the inhabitants and the physicians who wrote about it agreed in regarding it as an endemic malady. They also saw that a disease so prevalent and yet so local must needs have a cause both widely diffused and limited in the extent of its operation. The cyder made and consumed in the county answered to this description, and was accepted as the true cause. Mus- lo S/r George Baker, and grave, who wrote in 1703, and Huxham in 1739, adopted the popular behef, and differed only as to the particular property in the cyder which gave rise to the disease, the one ascribing it to its crudity and sharpness, the other to the tartar it contained. Huxham's tartar theory was the more plausible of the two, for it seemed to link together, as due to this cause, the colic attributed ahke to the wine of Poictou, the rum of Jamaica, and the cyder of Devon- shire. But Sir Georo^e Baker, who had lons^ doubted this theory, thought he saw, in the symptoms of the Devonshire disease, the working of tlie poison of lead ; and he deemed it eminently improbable that two things so unlike as apple juice and lead could give rise to the same symptoms. Lead, then, being such a poison as would account for all the symptoms of the disease. Sir George will go in search of it^ expecting to find it in some shape or other in the cyder. But first he will do justice to an anonymous French author, who seems to have anticipated him ; and he will also ransack ancient Greek and Latin authors in search of in- formation about lead and its effects. Then, returning to Musgrave and Huxham, he shows that crudity and sharp- ness in liquors is productive rather of diarrhoea than of the constipation that attends the colic j while tartar shares with acid liquors the power of curing it j and that the wines of Poictou, when the disease prevailed in that part of France, were adulterated witli litharge : and he cites a happy illus- tration from Zeller which (like a two-edged sword) cuts both ways, to the effect that the inhabitants of the neigh- bourhood of Tubingen drank with impunity wines as sour as vinegar, till they came to be adulterated with lead, and that then the colic showed itself. Sir George nextshows that the Devonshire colic is most prevalent when cyder is most abundant j that it attacks persons of all ranks who drink it, but that, as Dr. Wall, of Worcester, tells him, the cyder- making and cvder-drinkin^ inhabitants of Hereford, Glou- The Lead Poison. 1 1 cester, and Worcester, do not suffer. He now submits several specimens of Devonshire cyder to chemical exami- nation with others from Hereford j and finds lead in the former, not in the latter — indications of lead and the metal itself; lead from cyder in the cask, lead from cyder in bottle. The next step is to discover the source of this lead impregnation ; and he traces it to a practice almost peculiar to the county of Devon, of mending the stones of the presses with iron cramps, fixed by melted lead ; to another practice of lining the presses entirely with lead ; to another of nailing sheet lead over cracks ; to another — namely, the use of leaden pipes to convey the juice from the presses 3 to another, to wit, the putting a leaden weight into the casks to prevent the liquor growing sour ; to still another — namely, boiling the must in vessels deepened by a rim of lead. Add to this employment of lead in the making of cyder, what was probably too largely practised^ the use of it and its salts to correct acidity, and we are at no loss to account for the prevalence of the colic and its attendant paralytic and nervous disorders throughout the length and breadth of the county of Devon. On the other hand, Dr.Wall, of Worcester, alleges that the freedom from colic in the counties of Hereford, Gloucester, and Worces- ter was coincident with the absence of lead from their cyder-making apparatus. The number of persons suffering from this unexpected cause must have been considerable ; for in a period of less than five years, ending with 1767, 28^ cases were received into the Devon and Exeter Hospital, of which 209, or about three in four only, were cured. The more obstinate cases were sent to the Bath Hospital, and of these about half were cured. Of the patients, it appears that Devon- shire contributed eight for one from the counties of Hereford, Gloucester, and Worcester. The colic there- fore was not confined to Devon j but existed to a limited 12 A Siiigtdar Disease. it is passing away. How it selects its victims we do not know, and cannot be expected to learn. Some whom it kills quickly seem in the rudest health, others who are longer in dying are obviously less vigorous. Whether a man is to succumb or recover, probably depends in part on the strength of the dose, but in part on his having, or not having, some unsound organ which will not bear the congestion of the cold, or the quickened circulation of the hot, stage. The intemperate man is always taken at a disadvantage, and the chances of escape lessen with age. Another fact must be specially noted, as common to all epidemics — the poison, when it does not kill by sudden shock, remains for a variable period, in some shorter, in others longer, inert. The seed is sown, but takes time to- germinate. The interval of real or apparent inaction is known as the period of biculation. It is not easy to fix the limits in these maladies. In cholera it is thought to extend from three days to a week ; in typhus fever from a few minutes or hours, to a few weeks or months. The fact that there is this period of inaction, or incubation, helps to explain some apparent anomalies. The cholera, considered as a type of the class to which it belongs, has one or two other characters worth noting. It has been more than once preceded by the milder epidemic, in- fluenza ; it has given something of its own character to other diseases prevailing before, during, and after its own. visitations j it has seemed to require time to develop itself in the several places which it attacks, for several weeks will sometimes elapse before the weekly deaths exceed one or two ; and it is certainly, as a general rule, fostered and promoted by overcrowding and uncleanli- ness. This rude sketch of cholera will apply, with little Scarlatina. 41 modification, to all diseases of the epidemic class, which have been imported from abroad, and have not become- naturalized among us. Let us now look to our numerical returns, and see what they teach us respecting epidemic maladies j and? what light they throw on the question of contagion in the cases where that question finds place. I will take our annual reports first, and then our weekly ones. For the annual facts 1 refer to a paper of mine published in the "Statistical Journal," in i8^^, in which I reduced the figures for London, during the fifteen years from 1840 to- 1854, to a common scale of the deaths per million in a year of 2,^^ days. I will take the figures relating to the second cholera epidemic first, premising that there is a disease known as English cholera, but set down by the Registrar-General simply as cholera, which, in the fifteen years in question, never caused less than 15 deaths, and in more than one non-epidemic year, upwards of 60. Well! in 1847, ^^^^ deaths were ^2 j in 1848, 292 (marking the beginning of an epidemic) 3 in 1849, ^^^^X ^°^^ ^^*^ 6209 3 and in the following year fell to 55. Again, the influenza, which, in 1845, occasioned only 35 deaths, and in 1846, 55, is credited with 5O2 in 1847, and 295 in 1848; and it fell to 56 again in the great cholera year, 1849. Now these figures are in harmony with the notion of an imported pestilence, and with all that I have been saying about cholera as a good example of a pestilence imported, but not naturalized. In the first year, its victims- are comparatively few 3 in the second, very numerous j and the influenza, its forerunner, closely resembles it. Let us now turn to Scarlatina, the most fatal of our naturalized epidemics. In no year of the fifteen did it cause less than 354 deaths 3 but in 1848, it occasioned 2132. To this number it rose from 643 in 1847, ^"*^ from it, it fell to 943 in 1849. In 1850 the deaths were 42 Is Consimiptioii Contagious f 507. The figures harmonize completely with the notion of a disease always active, sometimes raging with epide- mic violence. Let us now see how the ligures stand for some one epi- demic of the Plague, say for 1665. -^^^ ^^^^^ X^^'' ^^ deaths were upwards of 68,000 j the year previous only 63 the year following, 1998 3 and the year after that, 0^^. So that, just as now we have an English cholera and an im- ported Asiatic epidemic cholera, in more remote times we had an English disease entered on the Bills of Mortality as plague, and an imported Oriental plague 3 and in both cases the figures are consistent with the idea of an im- ported pestilence, not naturalized among us. Next let us take Bronchitis. In no year of the fifteen did it cause fewer than 271 deatliS3 but in 1853 it destroyed 2083. But, inasmuch as it occasioned 1552 deaths in 1852, and 1814 in 1854, it is obvious that we have to do with a disease which may be rendered more fatal one year than another by such a cause as a cold season, but which lacks the strong numerical contrasts of an imported epidemic 3 as, indeed, do our naturalized pesti- lences. And lastly, let us take the eminently fatal disease. Pul- monary' Consumption. The lowest figure for the million inhabitants of London in any year is 2645, ^"^ ^^ highest 3941 3 and the fluctuation from year to year is very slight. I will give you the figures for three consecutive years : — 1849, -777 3 ^^5°» ^^45 5 ^^5^* -97°- ^^> then, any one were to assert that this disease is contagious, which is tanta- mount to saying that it may be epidemic, the figures I have quoted would in themselves furnish an answer in the negative. They are suggestive of a domestic disease in- fluenced, as is bronchitis, by the seasons and weather. Let us now look at the weekly returns for the six diseases of which I have been speaking — cholera, plague. Cholera and Plague. 43 influenza, scarlatina, bronchitis, and pulmonary consump- tion. As I have the figures at hand, I will take the cholera epidemic of 1854. Now, for more than half a }'ear (till the middle of July) no weekly entry of deaths from cholera exceeded 2, and more than once, for many successive weeks, no death by cholera w^as reported. But for tlie week ending July i (J, there was an entry of 5 deaths 5 and now the epidemic seems to have set in, for the next week the deaths were 265 the next, 133 j the next to that, 399 3 then 644, and so the disease went on increasing week by week, till in the eighth week it reached its maximum mor- tality of 2050. It took thirteen weeks to fall again to 5, and the next week to that the deaths were 2. It may be said to have prevailed twenty- one weeks, during eight of which it rose progressively, and during thirteen fell. There was no fluctuation. I now take a year of the plague, 1625. From the first week in January there were •entries of deaths varying from i to 5, with more than one blank week; then on March 14, we have the first of a series of unbroken entries, 4, 8, 11, 10, 24, 25, 26,30, 45, and so on, till, after twenty-two weeks, the maximum -entry of 4463 is attained, and then, in seventeen weeks more, the deaths have fallen to zero. The epidemic has passed away. Now, between these epidemics of cholera and plague there is an unmistakable resemblance. They are evi- dently diseases of the same class. The figures on the de Chauliac, who practised at Avignon — all the accounts conspire to justify Hecker's statement, that " It was an •Oriental plague, marked by inflammatory boils, and tumours of the glands, such as break out in no other febrile disease;" to which I must add that it often proved fatal on the second and third day, in the midst of profuse dis- •charges of otfensive smelling blood from the lungs, such discharsres as we now know to attend and characterize ofan- grene of those organs. Guy de Chauliac, than whom we can have no better authority, divides tlie whole epidemic of seven months into two stages of two and five months, respectively, of which the flrst was characterized by the i)loody discharges from the lungs, the second by the charac- teristic plague-tumours. I shall condense de Chauliac's account, as quoted by Anglada, with the pref^ice he so well •deserved. " I speak of Guy de Chauliac, one of the glories of -our school" (Montpellier), "one of the great medical characters of his age. Attached to Pope Clement VI, , he had himself an attack of the prevailing malady, which, by a happy exception, spared his life. Slave to his noble duties, he remained immovable at his post, in the midst of the universal panic, while his colleagues meanly sought safety in flight." This is the brave doctor's account of the disease : — and the Black Death. 4^ The mortality set in in the month of Januar}', 1348, and lasted seven months. It was of two kinds : the first lasted two months, with continued fever and spitting of blood, and people died of it in three days 5 the second lasted live months, also with continued fever, and apos- thumes and carbuncles on the external parts, and chiefly in the armpits and groins, and people died of it in five days. The disease (especially that form of it attended by spitting of blood) was so contagious that not only by being with the sick, but by looking at them, one took it of another 3 so that people died without servants, and were buried without priests. The father did not visit his son, nor the son his father. Charity was dead, and hope extinguished. The disease was so fatal that it scarcely left a fourth part of the people alive. Medical, treatment was useless, for all the sick died, except a few at the end, who escaped with ripe buboes. For preservation there was nothing better than flight. Aloetic pills • letting of blood 3 purification of the air by fire 3 comforting the heart by theriaca, apples, and things of good odour 3 con- soling the humours by bole armeniac, and resisting putre- faction by acid things, were recommended as preservatives. For the cure, bleeding and evacuations, electuaries and cordial syrups 3 tigs and cooked onions mixed with plan- tain and butter, to ripen the swellings, followed by inci- sions and the usual treatment of open sores. The car- buncles to be cupped, scarified, and cauterized. " And T," says the good doctor, " to avoid shame, dared not absent myself, but, in constant dread, preser^'ed myself as well as I could by means of the remedies above described 3 but, nevertheless, towards the end of the mortality, I fell into a continued fever, with a swelling in the groin, and was ill more than six weeks, in such great danger that all my friends thought that I should die. But the swelling E ^o Mortality. ripening under the treatment I have described, I escaped by the mercy of God." The mortahty due to the disease cannot be exactly ascertained for want of censuses and registers of death ; but doubtless it was on a grand scale. We infer this partly from numerical statements and partly from more general accounts. Let us take them by cities, communi- ties, and nations. Aleppo lost 500 a day, Gaza 22,000 in all, and Cairo 15,000. Genoa lost 40,000, Parma the same number, Naples 60,000, Siena ^0,000, Rome an incalculable number. Venice, out of a population of 200,000, lost 70,000, saw 90 patrician families extinguished, and its grand council of 1250 reduced to 380. In Florence, 100,000 perished between the months of March and July. In Spain, Valencia lost 300 a day, and many districts of Barcelona were depopulated. In Germany, at Vienna, the deaths were 1800 in one day, and 40,000 in all. At Erfurt 12,000 were interred in one cemetery. In France, at Avignon, 1800 died in the first tliree days, 150,000 in the city and its environs, and at the very first, 6^ monks in a Carmelite monastery 5 there, too, died Petrarch's Laura. Montpellier was very nearly de- populated, 10 out of 12 consuls dijd, not a monk survived, and few medical men. Marseilles lost in one month 36,000, and the bishop and his chapter all died. Nar- bonne suffered a loss of 30,000, from which it never recovered. Paris lost 50,000, and Saint Denis 16,000; and for many days together the Hotel Dieu sent 500 corpses to the cemetery of the Innocents. We lost here in London 100,000. Passing from cities to nations, we find the mortality in China, whence the plague is supposed to have sprung, set down at thirteen millions j in Germany it was 1,244,434 j Europe is supposed to have lost an aggregate of forty Consequences. millions, and Asia and Africa (exclusive of China) twenty-four millions. If we take classes of persons, we lind the order of Minorites in Italy credited with 30,000 deatlis, and the iFranciscan Friars in Germany with 124,434, We have, Hecker says, *'more exact accounts of England," and he specifies Yarmouth, Norwich, Bristol, Oxford, Leicester, York, and London as cities that suffered *' incredible losses." In Yarmouth 7052 died, in Norwich, 51,100, in London 100,000, a number in some sense confirmed by the statement that, " in one burial ground alone, there were interred upwards of 50,000 corpses, arranged in layers, in large pits." That a truly frightful mortality did prevail over the whole of Europe may be inferred from such statements as these : — " Cyprus lost almost all its inhabitants 3 and .ships without crows were often seen in the Mediterranean, as afterwards in the North Sea, driving about, and S2)reading the plague wherever they went ashore." Speaking of France, Hecker says that, in many places, *' not more than two out of twenty of the inhabitants were left alive," and of Paris that " more than 500 a day died in the Hotel Dieu, under the faithful care of the sisters of charity," to -whom he ])ays a deserved tribute of praise. At Avignon, we are told, that " the Pope found ir necessary to consecrate the Rhone, that bodies might be thrown into the river without delay, as the church-yards would no longer hold them." Such was the fearful loss of life which entitled this pestilence to the name of the Great Mortality. Here in England the pestilence had consequences worth noting. It found us with " a superabundance of all the necessaries of life," but it was followed by a " fatal murrain ■among the cattle," and this, with the lack of labourers to gather what was a plentiful harvest from the fields, led to E 2 Antecedents. a great rise in the price of food. Hecker's history, as it relates to England, ends thus : — " For a whole year, until it terminated in August, 1349, ^^ Black Death prevailed in this beautiful island, and everywhere poisoned the springs of comfort and prosperity." But here, as throughout Europe, the pestilence had also antecedents worth noting. The times were very barbarous. Kings were in constant conflict with powerful subjects, or engaged in external wars 3 cities were fortresses j the roads were beset with marauders 3 the husbandman was a serf 3 human life was of little account 3 witches and heretics were burned alive, and the Jews subject to cruel tortures 3 " wild passions, severity and cruelty, ever}'where predominated3" and (what is more to our present purpose) the cities were " with few exceptions, narrowly built, kept in a tilthy state, and surrounded with stagnant ditches." These conditions, even in those early times, Mere recognised as favourable to the spread of pestilence, as were personal uncleanliness and intemperate habits. The cities in tliose days were so built as to be eminently favourable to that overcrowding now so universally recog- nised as a most efficient cause of disease. Armies also,, which are crowds in the worst form, were in constant motion. We had a deadly feud with France, and Calais, surrendered to Edward III. in 1347 5 ^"^ ^'^ \\2i\'Q an excellent illustration of the mischievous agency of armies- in spreading contagious maladies in the fate that befel the Scots. They are stated to have been free from the pesti- lence till they made an irruption into our territory. This issued in the destruction of their army by the sword and the plague together, *' and the extension of the pestilence through tliose who escaped, over the whole country." On the continent of Europe, the crowds that followed the processions of tne Flagellants certainly promoted the spread of the Plague. Prcvcniive Measures. 53 Of the treatment of the Black Death I have nothing interesting or instructive to tell you. But something may be said with advantage of preventive measures. Hecker tells us that the first public measures of defence against the Plague were adopted within a few years after the passing away of the Black Death ; and he cites as the first sanitary code certain regulations of Viscount Bernabo, dated 17th January, 1374. " Every plague-patient was to be taken out of the city into the fields, there to die or to recover. Those who attended upon the plague-patient were to remain apart for ten days." " The priests were to examine the diseased, and point out to special commis- sioners the persons infected, under punishment of the con- fiscation of their goods, and of being burned alive. Who- ever imported the plague, the State condemned his goods to confiscation. Finally, none except those who were ap- pointed for that purpose, were to attend plague-patients, ■under penalty of death and confiscation." Viscount John, the successor of Bernabo, in the year 1399, when the P^^g^^e broke out in Italy for the sixteenth time (to say nothing of frequent visitations of measles and small-pox), enforced measures which would do no dis- credit to a sound sanitary reformer of our own time. He " ordered that no stranger should be admitted from infected places, and that the city gates should be strictly guarded. •Infected houses were to be ventilated for at least eight or ten days, and purified from noxious vapours by fires, and by fumigations with balsamic and aromatic substances. Straw, rags, and the like were to be burned 3 and the bed- steads which had been used, set out for four days in the Tain or the sunshine, so that, by means of the one or other, the morbific vapour might be destroyed. No one was to venture to make use of clothes or beds out of infected dwellings, unless they had been washed and dried either at the fire or in the sun. People were, likewise, to avoid. 54 Lazarettos and Ouaraiitiiic. as long as possible, occupying houses which had beeir frequented by plague-patients." These regulations go far to show what was then thought by learned physicians of the nature of the disease ; and I cannot do better than quote Hecker's summary of the prevailing notions and views : — That the pestilence, OY epidemic constitution, is the parent of various kinds of disease 7 that the plague sometimes, but not always, originates from it ; that in modern language the penti/ence bears the same relation to contagion that a predisposing does to an occasional cause, and that the conviction of the contagious power of the disease was universal. This persuasion of the contagious character of the Plague bore fruit in later times in Italy. In 1485, a special council of health was appointed in Milan, and lazarettos- were established on islands at some distance from the city. Somewhat later (in 1504) this council had conferred upon it the power of life and death 3 and later still (in 1527)' bills of health were introduced. The lazarettos on the islands were for the detention of strangers coming from suspected places. But when the plague appeared in the city itself, the sick with their families were sent to the *'old lazaretto," where they w^ere furnished with provi- sions and medicines j and when cured were despatched to another island lazaretto, where they, and all who had intercourse with them, were detained 40 daysj hence the word quarantine. I have some obser\-ations to make on the moral, religious, and political consequences of this great mortality j but these I reserve for the beginning of my next lecture, in connexion with the subject of mental epidemics of which the most remarkable outbreak signalized the epoch of the Black Death. 55 LECTURE III. THE SWEATING SICKNESS. Ix my last lecture I described the Black Death of the four- teenth century in its physical aspects, with its antecedents and accompaniments of terrestrial and atmospheric distur- bances, the barbarous and unsettled life of the people, and the filthy and unwholesome state of the great centres of po- pulation. I have now to treat of what I may call its mental aspects ', and this I shall do under the distinct heads of moral, religious, and political. This done, I shall notice briefly those strange outbreaks of nervous disorder which in a remarkable degree characterized the epoch of the Black Death, though they were by no means peculiar to it, I shall then say a few words about the Black Death as it affected us in England, and pass on to the sweating sick- ness. Of the mental effects of the Black Death, it has been said that it gave to all nations a shock '' without parallel, and beyond description." Its effects on morals, by which I mean the actions prompted by the natural emotions and passions of man- kind, other than those that flow from religion, must have been of a mixed character. The kind and generous, always a small minority, were doubtless moved to acts of heroic self-sacrifice ; but the indifferent and selfish (a far more numerous class) were guilty of acts of base desertion ; the harsh and unfeeling grew cruel j the criminal class found rare opportunities for the indulgence of their predatory habits ; and those addicted to the worst forms of dissipa- 5^ Religions and Political Co)iscqncnccs. tion sinned under the pretence that the natural result of their vicious practices would prove a safeguard against the more fatal infection of the plague. AVe read therefore, without surprise, that "parents abandoned their infected children, and all the ties of kindred were dissolved;" that " morals . were deteriorated everywhere;" that at Florence, as elsewhere, " the influence and authority of every law, human and divine, vanished ;" that, in a word, selfishness assumed such gross forms that it became a common practice " to barricade the doors and windows of houses infected with the plague, and to suffer the inhabi- tants to perish without mercy." The religious efl:ect of the black death in those super- stitious ages was to intensify every prejudice and heighten every dislike. The Jews were accused of poisoning the wells and streams, and were burnt, banished, or forcibly baptized by thousands and tens of thousands ; or driven to wholesale acts of suicide : while the processions of the Flagellants exhibited a ghastly spectacle of nervous dis- order, debasing superstition, and vicious self-indulgence. These scenes of cruelty and horror were not, however, quite unrelieved. History records acts of devotion on the part of some of the monastic orders ; and we read of the sisters of mercy in the Hotel Dieu dying at their posts, their places at once filled up by willing and devoted women, " strangers to the unchristian fear of death :" so that even to the dark religious aspects of the pestilence there was a silver side. The political consequences of the black death are be- lieved to have been very important. Hecker traces to it an immense accession of wealth to the clergy, and Leek}- a sudden taste for luxurious living among all classes. It certainly raised the wages of labour everywhere, and added weight and importance to the working class. As a class it suflfered frightfully ; as a class it obtained this compensa- Pi'occssiojis of the Flagellants. .57 tion. In my first lecture I quoted other passages in proof of the profound social and political consequences which the pestilence produced. When speaking of the religious effects of the black death I might have noticed with propriety the proceedings of the Brotherhood of the Flagellants, Brethren of the Cross, or Cross Bearers, which took its rise in 1349, when 200 of them made their appearance at Strasburg, were joyfully received and hospitably lodged 3 soon grew to a multitude j spread themselves over Germany, Hungary, Poland, Bohemia, Silesia, and Flanders j and moved from place to place, inflicting on themselves their strange penances. How the movement, at first superstitious, degenerated into a mixed mob of ignorant and mischievous fanatics opposed to the Church and hostile to the State j how the Pope put a stop to the pilgrimages by threats of excommunication 5 how kings resisted them j and how, at last, they became objects of bitter persecution, you will find set forth in the pages of Hecker, which also contain learned notices of similar processions of Flagellants in the eleventh, thirteenth, and earlier part of the fourteenth centuries. I may also refer you to Hecker's work for a very complete account of the Dancing Mania, which, beginning in the thirteenth century, showed itself at in- tervals in the fourteenth and fifteenth centuries. Dr. Babington's translation is enriched by interesting notices of similar convulsive diseases occurring in later times in Scot- land. The processions of the Flagellants form part of the sani- tary history of the Continent, and especially of Germany, where they took their rise. I shall not, therefore, consider them as belonging to my subject, or discuss, as I am tempted to do, the interesting question whether these manifestations of a disordered mind and nervous system may be directly attributed to the same atmospheric con- Poisoned Water. ditions that so fatally affected the body, but shall resume the subject of the Black Death as it relates to England. The accounts of the disease in England are in harmony with those which have come to us from Italy and other parts of the Continent. 'vVe read of the same atmo- spheric disturbances, with the addition that its advent was preceded by great floods. " It rained from Christmas to Midsummer, without one fair day 3" and when it left us " there followed a great dearth of cattle j after that a dearth and scarcity of corn." We read of 5000 cattle dying in one pasture, of beasts and sheep going wild through fields and ''corns," and dying in holes, furrows, and ditches, in innumerable multitudes over the whole kingdom, for want of keepers j of the scarcity and inso- lence of servants, and consequently, the next harvest, of corn rotting in the fields for want of hands. Short, from whose compilation I take these particulars, fixes the date of the arrival of the pestilence on the coast of Dorsetshire as September 28, 1347. -^^ ^^7-^ ^^^^ '^ reached Scotland and Ireland in '50 or '51, and that it did not finish its "perambulation over the world" before '60 or '62. He tells us that " if it was so favourable as to leave a third part of men alive in some few places, in others it took 15 out of 16 j" and that " in more it utterly extirpated the human race." He gives the deaths for Yarmouth at 7052 j for Norwich in six months, at 57,000 5 for London during three months, at 2000 a week. " It is said at a medium, to have killed 9 out of every 10." In England, as elsewhere, the Jews were accused of poisoning the springs 5 and this accusation Short traces to the fact that the water was pestilential even to the fishes. Of this wide-spread belief in the poisoning of wells and springs of water, not in the time of the Black Death only, but during all great epidemics, I may obser\'e once for all, that recent discoveries have rendered it highly probable- Bad Hoiis'uig- and Gross Feeding. 59 that the people were not always mistaken as to the fact of the poisoning, but only as to its nature and the persons who caused it. In those remote times, the state of the places in which men lived, and their habits of life, rendered the pollution of drinking waters by human excreta inevitable, and so secured the rapid spread of any contagious disease that happened to prevail. One curious ^statement, which is made by the same author, without any direct reference to his authority for it, is to the effect that "Tanners, curriers, such as cleansed bog-houses, servants in hospitals, and others employed in other nasty stinking businesses, all escaped infection." Of course^ in those remote times, there must have been the strangest misconceptions, the grossest exaggera- tions, the roughest guesses at truth 3 but in the midst of much that is false in degree if not in essence, there stands out in bold relief the great central fact, that in the middle of the fourteenth century, a pestilence not surpassed by any recorded in history, for the ground it covered^ or the destruction of life it occasioned, came to us from the East: that it had the characters of the bubo plague with spitting of blood superadded j that it attacked a large proportion of the population, and destroyed an equally large propor- tion of those whom it seized j that it disorganized society, inaugurated a reign of terror, gave free scope to ever)' vile passion and unworthy prejudice, and if it in any degree promoted religion and stirred up repentance and amend- ment of life, it was at the cost of a speedy and lamentable reaction. The dwellings and personal habits of the English people in town and country were such as to encourage to the utmost the pestilences we bred or im- ported. Judging from the descriptions of foreigners we were characterized by bad housing and gross feeding. The state of things is not likely to have been better in any respect, it was probably worse in all, than when in •^o Encrland in the Olden Time. 'the sixteenth century the Dutch scholar Erasmus wrote the letter which I am to quote when I treat of the Sweat- ing Sickness. Nor, on the other hand, was it likely to have been very different from the account given us by the •old chroniclers, Holinshed, Stow, Baker, and Martin. After careful perusal of the extracts which I have made from their works, and reference to Pearson, Rogers, and after this, except Thames Street, and from Ludgate to Charing Cross, neither was the great City of Paris paved until the year 1186." London, therefore, in the middle of the fourteenth century was almost wholly unpaved. In the middle of the twelfth century, if we may credit the monk, William Fitzstephen, who died in 1191, London consisted of two long narrow tracts of land, separated by the Thames, which then abounded in fish. It was surrounded 6z London ill the Tzuclftli Century. with hisli ^valls, strenoftbened with towers and double inites, with a " tower palatine " on the east, and two castles on the west, and the king's palace in the same quarter on the river, with its walls and bulwarks, separated by two miles from the city. The suburbs were studded with the houses of the citizens, with their gardens and orchards. On the north, there were pastures, and meadows, and plentiful corn lields ; and near at hand was a large forest, with wild beasts, bucks and does, boars and bulls. Here, too, were flowing waters, and busy water-wheels and foun- tains, sweet, wholesome, and clear, welling forth among the glistening pebbles. There was Holywell, and Clerken- well, and St. Clement's well, the resorts of scholars and youths on summer evenings. Without one of the gates was a certain Smoothfield (now Smithfield), where horses were sold. In the city there were common sewers, and conveyances for water in the streets. For amusements there were miracle-plays, land-fights and water-lights, leaping, shooting, wrestling, ball and stone-throwing, casting the javeline, cock-fighting and baiting of boars, bulls, and bears. The city mustered the improbable number of 80,000 armed men (20,000 horse and 60,000 foot). Its citizens were distinguished "for their civil demeanour, tlieir good apparel, their table, and their dis- course," and its matrons might compare with the Sabine women. There was abundance of provisions and good cooking, and " the only plagues of London are, immo- derate drinking of idle fellows, and often fires." Two centuries later this pleasant city was still unpaved, and even two centuries after that very filthy and unsavoury in-doors and out. Between the epoch of the Black Death and that of our next great Pestilence — the sweating sickness — in other words from 1347 to J 485, a period of nearly 140 years, England suffered something like a score of epidemics. The Sweating Sickness, 6 3 with their accompaniments of famine and cattle plague. Among these I note one of influenza, one of small-pox^ one of puerperal fever, two of bloody flux, and two of epidemic madness ! I must not stop to comment upon these, tempting as some of them are : but in reference to the last, I may raise the question whether the narrative given at page 12 of my first lecture does not justify the belief that the physical causes which usually give rise to bodily disease sometimes act directly on the mind. The Sweating Sickness, Pestilent Sweat, or English Ephemera (for by all these expressive names docs Dr. John Caius call it)^ has a special interest attaching to it, and, considering the remoteness of the period, our infor- mation about it is satisfactory and tolerably complete. It occurred once at the end of the fifteenth century, anil no less than four times during the first half of the six- teenth, or five times in all. Now the Oriental plague attacked London and England five times, once in 1593, and four times in the first 6^ years of the seventeenth century. Of the Plague, then, there were 5 epidemics in 72 years 3 of the sweating sickness, 5 in 66 years. But with this coincidence all analogy ceases. The 5 outbreaks of plague were not the only ones ; but the sweating sick- ness does not seem to have occurred in England before or since 5 certainly not as a highly mortal pestilence. This sweating sickness of the sixteenth century w.is quite a different disease from the black death of the fourteenth, and the Oriental plague of the seventeenth, between which it was, so to speak, interposed. It did not originate in a foreign country, thence to be conveyed by sea, after attacking other countries and cities, to this ; but it sprang into existence within our own limits (here in England), did not extend to Scotland or Ireland j and when it showed itself abroad, is alleged (with very rare exceptions) to have attacked only our own people. Nor 64 Dr. yoJin Cains. was it a contagious disease, in the sense in which the plague was contagious ; it did not develope any distinct cutaneous rash, no blains, boils, or carbuncles, no blood- spots, or large haemorrhages under the skin ; its victims were not indifferently men, women, and children, as were those of the Plague^ but mainly robust men in the prime of life ; its onset, unlike that of the Plague, was, witli the rarest exceptions, sharp and quick, and the mortal struggle which lasted for many days in most cases of Plague, was mostly an affair of less than four-and-twenty hours. Then, again, while the Plague consumed two or three years, and never, I believe, less than one, in its progress through the country which it attacked, and spent the greater part of a year, at least, in any great city which it assaulted, this sweating sickness would do its work of destruction, and sweep over a nation in some five months at the outside, and enter and quit a great city like London in as short a space of time as three weeks. The sweating sickness was not limited to England. It appeared in 1529 in Germany, Holland, Denmark, Swe- den, and Norway. But as tlie sickness of 1528 passed away (according to Caius) in July, and did not show itself in Germany till tlie same month of the year follo\^- ing, it is obvious that, on the Continent, it was due to the same atmospheric causes and personal habits as here in England : not to contagion. In giving you an account of this disease, I shall follow the course which I shall adopt in tlie case of the Plague, and which I prefer wherever I find it practicable. I shall deal with Dr. Caius as with Dr. Hodges j and having extracted from his *' Boke, or Counseill against the Disease commonly called the Sweate or Sweatyng Sicknesse," all the good metal it contains, turn to Hecker's and Anglada's account of the disease as it occurred on the Continent, for supplementary information. Lord Bacon. 6^ But as Lord Bacon, in his " History of Henry VII.," gives a very clear account of the first attack, in 1485, I will make a short abstract of it as a preface to the whole subject. Toward the end of September there began and reigned in the city, and other parts of the kingdom, a disease then new — this sweating sickness. It had a swift course, both in the persons attacked and the time it lasted ; for after 24 hours, patients were deemed nearly safej and it began September 21st, to end before the month of October was over. It was a pestilent fever, but not fol- lowed by carbuncle, or by purple or livid spots, and it terminated by an extreme sweat. It was "rather a sur- prise of nature than obstinate to remedies," for if it was treated as we should now nurse a common cold, people commonly recovered. But infinite persons died suddenly of it, before the manner of the cure and attendance was known. It was conceived not to be an epidemic disease, but to proceed from " a malignity in the constitution of the air, gathered by the predispositions of seasons j and the speedy cessation declared as much." The sweating sickness showed itself for the first time in the year 1485, soon after August 7th, when Henry VII. arrived at Milford Haven from France ; and it continued during the remainder of the month, and through all September. Caius gives us a vivid notion of its severity, when he says of those whom it attacked that it fearfully invaded them, furiously handled them, speedily oppressed them, unmercifully choked them ; and that in no small numbers, many of them being persons of rank and mark. It immediately killed some in opening their windows, some in playing with children in street-doors, some in on*.* hour, many in two, and, at the longest, ** to them that merrily dined, it gave a sorrowful supper." " As it found them, so it took them," some sleeping, some waking, some in mirth, some in care, some fasting, some full, F 66 Nature of the Disease. some busy, some idle, and in one house, three, five, seven, eight, or more, or all. So that if the half in any town escaped, it was thought great favour. This is the account which Caius gives of the disease at its first appearance in 1485. He then gives us the dates and brief particulars of the other attacks. The second was in 1506, the third in 151 7, the fourth in 1528, the fifth in 1 55 1. It is this last which doubtless supplied him with the best materials for his book published in 1552. In this, its fifth visit, it showed itself successively at Shrewsbury, in the middle of April, at Ludlow and other places in Wales, at Coventry and other towns in the south, and at places in and about the way to London. It reached London July 7th, and from the 9th to the i6th, killed 761 persons, and from the i6th to the 30th, 143 more ; making in all, 904 deaths, exclusive of deaths not registered on the 7th and 8tli. From London the sick- ness passed on to the East, and then to the North, of England, where it raged till the end of August, when it abated, and at the end of September ceased. The disease was a fever, followed by a sweat. It set in with pains in the back or shoulder, and in the limbs -, w ith flushes, oppression at the liver and stomach, pain in the head, delirium, and palpitation, followed by a man^el- lous heaviness and desire for sleep. Then (but this is not very distinctly stated) occurred the profuse offensive sweats, from which tlie disease derives its name. I infer from the treatment being directed mainly to two points — the promotion of perspiration, and the prevention of sleep — that the natural cure was free action of the skin, the common mode of death by coma. Patients suffering from this disease were very subject to relapses. They had them for the third, or fourth, and even as often as the twelfth time. And now as to the cause, or causes, of tliis sweating Peculiar to the English, 6-j sickness. We have to explain, if we can, the curicjus, but apparently well-ascertained fact, that this disease was limited to England and to Englishmen living abroad, in four out of the live epidemics ; also that other fact, equally strange, that the victims of the disease were not old men or children, bu^ robust middle-aged adults, of what Caius calls 'Miot and moist complexions j" wealthy men living in ease and comfort, or, if of the poorer sort, " idle per- sons, good ale drinkers, and tavern-haunters." ''The laborious, and thin-dieted people," the respectable poor, ^s we should call them, did not take the disease, or had it tavourably. "The intemperance, or excessive diet of England," which was a scandal to the French, and a reproach among the nations generally, was, in the judgment of our author, the predisposing cause of the disease, by bringing about a state of body favourable to the operation of the exciting cause, whatever that might be. Nor does the fact that the disease did once (in the year 1529) extend to Bra- bant and parts adjacent, shake his belief j for he groups together England, Holland, and Germany, as countries addicted to an "evil diet," "destroying more meats and drinks, without all order, convenient time, reason, or necessity, than either Scotland, or all other countries under the sun." So powerful and effective was this dietetic predisposition, that neither absence nor flight could pre- serve our countrymen ; for in Calais, Antwerp, and other places in Brabant, it was only Englishmen and persons using the English diet who fell sick. " This disease then, is almost peculiar to us Englishmen, and not common to all men, following us, as the shadow the body, in all countries, albeit not at all times." For such strong and reiterated statements, there must have been some founda- tion of fact. Gluttony and intemperance, then, as now, were powerful predisposing causes of disease. F 2 68 Sanitary PrecaiUions. Among a people addicted to such excesses we should scarcely expect anything approaching to effeminacy. But yet, Caius accuses his contemporaries of being ''unwisely fine and womanly delicate." He complains that " the old manly hardness, stout courage, and painfulness of Eng- land," were utterly driven away, and that, in their stead, men had become effeminate, and nice, and not able to withstand a blast of wind j while children, *'if they were not all day by the fire with toast and butter, and in their furs, they were straight sick." Concerning the exciting cause of the disease Caius has little information to give us. He sees that it must be in the air, and he alludes to stinking mists seen to fly from town to town, so offensive morning and evening that men could scarcely abide them. When he comes to the question of preservation, or, as we should now call it, prevention, our author prescribes moderation in diet, with details as to fruits and vegetables which may be taken to prove that such wholesome things were at that time in common use j and also measures tending to insure purity of air inside and outside the dwell- ing. He would make a " sweet house " by means of sundry odours and perfumes, after having made it clean by removing the rushes and dust, with which, as we know, the floors of the best houses, and even of palaces, were strewn. Juniper berries, or a mixture of myrrh, rose- leaves, and frankincense, were also to be burnt on the coals. Outside the houses the air was to be improved by filling up ditches, removing carrion, mending with earth muddy and rotten grounds, burying the dead, keeping gutters clean, and sinks and easing places sweet, removing dung- hills and ill-smelling things, drying moist air with fires, and so forth. Personal cleanliness and well-washed hands and faces Medical Treatment. 69 are also commended as great aids to health, and clean clothes and suitable exercises. Men should not go out in the morning tasting j they should smell to scented hand- kerchiefs, and take, the first thing in the morning, a little mithridatum, or some other harmless and useless confec- tion. Of quack medicines and charlatans from every nation under the sun, of remedies so filthy that he was ashamed to mention them, of the aurum poiabile, and waters the products of six months' continuous distillation, costly in proportion, Caius gives us examples more than enough. The cure or remedy for the sweating sickness consisted in a four-and-twenty hours' rest, the patients being all the time guaranteed against the slightest exposure of the body or any part of it to the air, and the sweat being rather en- couraged than forced. They were to have no food for twenty-four hours, and no drink for five; and special care was to be taken in the 4th, 7th, 9th, nth, and 14th hours. Clarified ale, with a little sugar, might be given the 5tli hour, and sweating, if not sufificient, was to be encouraged by frictions and warm drinks. For de- lirium he prescribed rose water and vinegar to the nose; and if the patient slept or fainted he was to be beaten, scolded, and pulled by the ears, nose, or hair. He was .not to be allowed to sleep till he had no desire to do so : this rule to be broken only under the advice of a learned man in physic. This strange treatment we shall see was adopted by Hodges in the Plague. I have not, I believe, omitted anything interesting or important from this book of Dr. Caius. You have before you a rude and imperfect sketch of a disease wholly unlike the Oriental Plague, and yet having all the attributes of a great epidemic. Bred in England, nursed by English habits and modes of life, largely prevailing among the .adult population, and destroying many of those whom it .attacked in an incredibly short space of time, making but The Diet of the English. a short stay in any one place ; such is the sweating sick- ness of the sixteenth century. Caius's account I have said is imperfect 3 but Hecker is able to supply its de- fects from other sources, English and German, Among the symptoms he mentions a livid and bloated countenance, great difficulty of breathing, vomiting, intense thirst, convulsions, and a whining and sighing voice 5 and diarrhoea in some cases after the worst symptoms had sub- sided. The occasional occurrence of death before the ap- pearance of the characteristic sweat, as sometimes happens in plague and cholera, is also noted j and we are told too that convalescent patients remained very feeble for a week or so, and that few stirred out till the second or third day. Of the antecedents and causes of the disease Hecker gives an abundance of details. We learn that the first,, third, fourth, and fifth attacks were all very severe ; the second exceptionally mild 3 that the first, fourth, and fifth were preceded by great inundations, and the fourth attended with great scarcity of provisions ; that as the first outbreak of 1485 was traceable to the army of free- booters and mercenaries who fought at Bosworth, so the third of 1517 took place in London, crowded with foreign artisans from every country in Europe ; while the fourth of 1528 coincided in point of time with the great military operations of Francis L, and his allies in Italy and before Naples. Nor were there wanting in these epidemics, and especially in the last of them, atmospheric disturbances, and unusual developments of the lowest forms of life. There were floods and storms 3 and in Germany mould-spots reappeared on clothes, and red discolorations of water. Among the predisposing causes, in other words, the con- ditions that had prepared the bodies of men to receive this peculiar infection from the air, tlie diet and mode of life of the robust adult population of England receive, at the Letters of Erasmus. hands of Hecker, as of Caius, due attention. J will follow their example, and will Xxy to represent to you the English as they then lived. I will first read an abstract of the often quoted letter of Erasmus to the physician of Cardi- nal Wolsey. He grieves and wonders that Britain had for so many years been afflicted with a continual plague, and chiefly with the sweating-sickness^ a malady that seemed almost peculiar to it ; and he thinks that it might be freed from the disease by reforming its buildings. He finds fault with the aspects of the houses, and the construction of the sitting-rooms, in which great parts of the walls were filled with plates of glass that admitted hght but excluded air. He tells us that the streets were generally co- vered with clay and rushes, which sometimes remained undisturbed for twenty years, concealing a mass of filth not fit to mention, and exhaling a vapour not wholesome for the human body. This ancient collection of filth was doubtless nothing less than the successive contributions made by the houses themselves ) for from another letter by the same hand we learn that "the floors of the houses generally were made of loam strewed with rushes, con- stantly put on fresh, without removing the old, lying there in some cases for twenty years, concealing fish-bones, broken victuals, and other filth, and impregnated with the urine of dogs and men. The existence of this nauseous state of things is confirmed by Caius's directions for fumi- gating rooms, which were to be put in practice after the removal of rushes and dust. It is easy, therefore, to credit Erasmus when he says, " If, even twenty years ago, I had entered into a chamber which had been uninhabited for some months, I was immediately seized with a fever." Erasmus then notices the fact that many parts of England N\Tre marshy and intersected by salt streams, and that the common people were amazingly fond of salt food. To make our island and people healthy he recommended the /- English Intemperance. disuse of rushes, the building of chambers so as to be ex- posed to the heavens on two or three sides, glass windows made to open and shut, a more sparing diet, and more moderate use of salt provisions, and the appointment of officers to keep the roads more free from nuisances. All this Erasmus writes in no carping spirit, for he loved the country that had so long given him an hospitable abode ; and would willingly spend the remainder of his life there. But this letter of Erasmus gives us only an imperfect idea of the Scythian tilth of human dwellings, and the coarse, unwholesome habits of life among our ancestors at the time that the sweating sickness prevailed amongst them. The tributaries of the Thames were large filthy streams, bearing boats, ships, and even " navies " on their foul, reeking bosoms. What their condition must have been at that time, we may infer from the well-known lines in the Dunciad, written early in the eighteentli century : — " To where Fleet ditch, with disemboguing streams. Rolls the large tribute of dead dogs to Thames, The King of Dykes ! than whom no sluice of mud. With deeper sable blots the silver flood." These tributaries of the Thames were, I should think, much in the state of the water surrounding the noto- rious Jacob's Island, in the middle of this nineteenth cen- tury, when the same filthy stream served tlie common purpose of sewer and water-supply j and so prepared its wretched neighbours for the visitation of the cholera. As to diet and clothing, we are able to collect this additional information. Both high and low were ad- dicted to intemperance J and this English vice passed into a proverb in foreign parts, as appears from a passage in Milton's Areopagitica, in which he speaks of " household gluttony" as a ^Miational corruption, for which England hears ill abroad." Flesh meats, highly seasoned with spices, were eaten to excess, strong wine was drunk early What the Sweatijig Sickness was. 73 in the morning, and noisy nocturnal carousings were customary. English cookery was wholly wanting in re- finer»ent, and pot-herbs were scarce. The clothing of the period was immoderately warm, and the head was covered with thick caps, of which the inner one, of velvet or satin, was close fitting. Hot baths also were much in vogue, and diaphoretic medicines were prescribed in most disorders. Soap was little used, and linen was dear. It was by such habits and customs that our ancestors prepared themselves as fitting victims of a disease charac- terized by profuse sweating. We have but to suppose exceptional weather, heavy falls of rain and consequent inundations J a certain '^ epidemic constitution" of the air, large gatherings of soldiers or civilians, and a nation of gluttons and drunkards living in filthy, unventilated houses in squalid, noisome streets, with their persons steaming in hot and uncleanly clothing, to be prepared for any conceivable amount of sickness and mortality. And now we come to ask ourselves this question — was the sweating sickness that visited us five times in the fifteenth and sixteenth centuries, a disease sid generis, or was it only an extreme degree of an epidemic with which in still earlier and in later times, we have been familiar ? Hecker discusses this question in a chapter headed, " Form of the Disease j" and he arrives at the conclusion that the Eng- lish sweating sickness was " a rheumatic fever in the most exquisite form that has ever yet been seen in the worlciy If Hecker means by this word rheumatic what we mean by the word catarrhal (as I have no doubt he does) he is probably right. I may add, that Mead, writing in 1722 of " the same kind of fever," as it occurred in 1713, when it was known as the " Dunkirk Fever," from being brought by our soldiers from that place, describes it as beginning with a pain in the head, and going off in large sweats, usually after a day's confinement. 74 ^ Alodijicd Influenza. For my own part, if I were asked to what disease this sweating sickness bears the nearest resemblance, I should say, either to an ague, with a short and faintly marked lirst and second stage, proving fatal in its first paroxysm, and, if not, running on to three, four, or twelve relapses j or to a modified and specially severe form of influenza, which, when it did not prove fatal, left behind it for some days a state of extreme weakness. Let us now see whether the second of tliese alterna- tives, to which I incline, is borne out by the account which Hecker gives us of the sweating sickness as it showed itself in Germany, Holland, Denmark, Sweden, and Norway in 1529. One feature of the Influenza, by which it is distin- guished from the Plague, and from all contagious epide- mics, is the short sojourn it makes in the places it attacks. Now we learn that the sweat continued in Hamburgh only nine days, in Stettin little more than a week, in Dantzig five days, in Augsburg six, in Amsterdam five. Taking what we call sporadic cases into account, it was an aflair, at the most, of a fortnight or three weeks. Anotlier feature of the influenza which the sweating sickness displayed is the simultaneous, or nearly simul- taneous, outbreak of the disease over a wade region or cir- cuit of cities. Now, the Sweating Fever broke out at the same time (in the beginning of September) at Stettin,. Dantzig, and other Prussian cities ; at Augsburg, far to the ^lOUth on the other side of the Danube j at Cologne on the Rhine J at Strasbourg, at Frankfort-on-the Maine, at Mar- burg, at Gijttingen, and at Hanover. It took possession of these cities " as it were by a magic stroke," " like a violent conflagration, which spread in all directions," the flames " rising up everywhere, as if self- ignited," and while this occurred in Germany and Prussia, tlie same thing was happening in Denmark, Norway, and Sweden, Other European Epidemics. K) perhaps also Lithuania, Poland, and Prussia. As to the period during which this disease continued to attack the nations of the Continent, we have reason to beheve that it did not exceed three months. It then " disappeared everywhere without leaving behind it any sign of its exis- tence, or giving rise to the development of any other disease." And it did not interfere with the "French Hunger Fever," or the " Italian Petechial Fever." If then the two characteristics of shortness of sojourn and simultaneous attack may be said to belong to the influenza, they certainly did belong equally to this sweat- ing sickness j and I may add that the small aggregate of deaths (probably not exceeding 1200, or, at the outside, 1500, in London during three weeks) — small when we consider the violent way in which it seized many of its. victims — is quite in harmony with what we know of the disease in our own day. The influenza, I may add, was one among the many epidemics that have made the sixteenth century memo- rable in the history of disease. ''It was," to use Hecker's words, " a century of putrid malignant affections 5 a cen- tury replete with grand phenomena affecting human life." So that what the same author says of the English Sweat- ing Sickness of 1^17 and 1551 — namely, that it "made its appearance, not alone, but surrounded by a whole group of epidemics, called forth by general morbific influ- ences of an unknown nature," is certainly true of the three other visitations, and notably so of the epidemic of 1528. The principal epidemics to which allusion is thus made were the Influenza 3 the Petechial Fevers of Italy, France, and Hungary- the Hauptkrankheit or Encephalitis of France and Germany 3 the Trousse-Galant of France 5 the epidemic flux, the epidemic scurvy, and the diphtheria. I shall ofive such a brief account of each of these as. 76 The Influenza. may sene to fill up the epidemic history of the sixteentli centur}'. Of the hijiuenxa I shall have to speak more at large on a future occasion. It is fully treated of in the " Annals of Influenza," edited by Dr. Theophilus Thompson for the lirst Sydenham Society, by Dr. Robert Williams, in his Avork on Morbid Poisons, and by Hecker, It has a special interest for the reason that influenzas are usually only *'fhejirst manifestations, liit sometimes also the last remains of extensive epidem ics. By a curious coincidence, there occurred in the course of this sixteenth centur}', 5 notable epidemics of influenza, as there were 5 of sweating sickness in the fifteenth and sixteentli, and 5 of plague in the sixteenth and seventeenth. The dates of the outbreaks are 1510, 1551, 1557^ 1564, and 1580. But w^e have notices of the same disease as ■occurring in the fifteenth centur}' — in France in 141 1 and 1414 J also in Ireland at a period not stated. It was in T414 that the French christened this disease Co(jueluche, or -the Monk's hood, from the head-gear to which it com- pelled tlie people to resort. The symptoms were those of a common cold — pains in the head, back, and loins 5 fever, often attended with delirium; nausea and loathing of food ; watering at the eyes ; hoarseness and cough ; and at last disagreeable eruptions about the mouth and nostrils, ■or bleeding from the nose, profuse perspiration, or diarrhoea. The disease was more remarkable for the number whom it attacked than for the deaths it occasioned. But it is probably an exaggeration to say that it was "unattended with danger." It prevailed in tliose earlier, as in these later times over an immense extent of territory. The Annals of hjliienxa contain notices and detailed accounts of epidemics, twenty in number, from the year 15 10 to the year 1837. This is all that I deem it necessar}'- to say at present of Petechial Fever. 77 this disease, which links together in so interesting a manner, the past and present of epidemic history. Petechial Fever. — This epidemic seems to have been first seen in Spain in 1490. It broke out in Granada, *' where it threatened to annihilate the army of Ferdinand the Catholic." But the first epidemic of which we have a good description, occurred in Italy, in 1505, nearly simultaneously with the second sweating sickness here in England. Fracastoro, an eminent Italian physician, de- scribes it as a contagious disease, less readily communi- cated by the person, and by clothes, than the bubo- plague, and chiefly to those in immediate attendance on the sick. The early symptoms were slight and obscure. There was weariness, as after great exertion, but not much heat of surface. The patients lay on their backs, with cerebral oppression, and blunted sensibility j and in most cases muttering delirium, with bloodshot eyes, set in from the fourth to the seventh day. The urine, clear and copious at first, became red and turbid j the evacua- tions were putrid and offensive ; the pulse was slow and small ; there was little thirst, but a loaded tongue ; a lethargic state in some, great restlessness in others. On the fourth day, or on the seventh, red or purple spots, like flea-bites, or lentils, broke out on the arms, back, and breast J and on the seventh or fourteenth, and in some cases later, the disease came to its height. It was most fatal to children and young people, especially among the higher ranks. This same fever, in a very malignant form, in the year 1528, the date of our third outbreak of the sweating sickness, extended throughout Italy, and followed Italians abroad ; and there is reason to believe that it attacked the troops of the French and their allies at the disastrous siege of Naples. And lastly, in the years succeeding the fifth outbreak of the sweating sickness, in 1 551, as well as in the years Troussc-galant of France. preceding it, this petechial fever seems to have prevailed in the armies of the Continent. It is thought to have attacked the imperial troops in 1547, and the Hungarians in their camp near Komorn, in 1566. This fever seems to have been much mixed up with the Oriental Plague, and often confounded with it in the six- teenth century 5 and under the name of " spotted fever," figures in our London Bills of Mortality of the seven- teentli century. It has become naturalized in England, as one form of the typhus of modern times. The Hauptkrankheit, or Brain Fever, seems to have shown itself both in France and Germany — in France in 1482, after a two-years' scarcity j in Germany in [517. The disease, as it occurred in France, was an inflamma- tory fever with dehrium, and attended by such intense pain in the head, that many dashed out their brains against the wall, or rushed into the watery while others incessantly rushing to and fro, died in the greatest agony. The same disease scourged the north-west of Germany, as far as the shores of the North Sea, at or about the same date. We have no details by which to judge of its fatahty. The Trousse-galant of France, named from the speedy death it inflicted on young and robust men, followed fast upon the disasters of the French army before Naples, in J 5 28 3 and was the contemporary of a long and grievous famine, being carried about from place to place by the starving people in search of food. These people, it is haid, were so saturated with the poison of the disease, that they communicated it to persons in health without being themselves affected ; in this respect reminding us of our own jail fever, and of the fever that followed the Irish Famine. It was very inflammatory, often destroyed its victims in a few hours, and left those who recovered deprived of their hair and nails. The disease returned in Diplitkcria. 79 1545-6, and spread over Savoy and the greater part of France. The great French surgeon, Ambrose Pare, wit- nessed this second outbreak. The brain and nervous system were severely attacked, and headache followed by stupor, or extreme restlessness and delirium, were leading symptoms. In most patients, eruptions, not exactly described, but probably petechiae, showed themselves. The disease often terminated on the fourth or the eleventh day. Large quantities of thread-worms were discharged. It was eminently contagious, and was followed soon after by the true bubo-plague. It is thought to have been the same disease as the Dandy Fever, which prevailed in the West India Islands in 18285 and also in recent times, in France. The Epidemic Flux, which was probably dysentery, and not cholera, prevailed over great part of Europe in the cold summer of 1538. Scarcely a town escaped. Two years before this date (July 12, 1536), Erasmus died of it. We have no satisfactory account of its symptoms. The Epidemic Sciirvi/, so generally associated with epi- demic dysentery in modern times, seems to have been very prevalent in the sixteenth century. It occurred in Germany, Portugal, Ireland, and other countries in 1 496, and in Denmark in 1536, and 1557. I shall have to speak of it again when I come to the prevalent diseases of the eighteenth century. Diphtheria or Diphtherite is evidently to be counted among the prevalent and fatal epidemics of the sixteenth century. It broke out in Holland in January, 15 17, and was, therefore, contemporary with our sweating sickness of that date. It was an infectious inflammation of the throat, which often destroyed life in less than twenty-four hours. It set in with symptoms of cold, soon followed by inflam- mation of the air-passages, and this by inflammation of the lungs, with high fever. Those who ultimately 8o Last Half of the Sixteenth Century. recovered got well slowly. The disease appears to have made a very sudden onslaught, and to have passed away in the short space of eleven days. But it spread beyond the limits of Holland, and certainly to Basle, in Switzerland, where in the space of eight months, it killed 2000 people. Here its symptoms appear either to have been more strongly marked or better described. For we learn that ^' the tongue and gullet were white, as if covered with mould," and that part of the treatment consisted in re- moving this "viscous white coating" every two hours, and smearing the tongue and fauces with honey of roses. This fatal epidemic broke out again in October, 1557, at Alkmaar, where it destroyed 200 people in a few weeks, and laid more than 1000 people on their backs in a single day. It lingered longer than on its first out- break, and was certainly less severe. The diseases which I have just passed in review as being prevalent in Europe at or about the times when our Sweating Sickness was afflicting us, — the Influenza, the Petechial or Spotted Fever, the Brain Fever, the Trousse- Galant, the Epidemic Flux and Scurvy, and Diphtheria, were not the only maladies of this pestilential century. Syphilis, which was certainly known in England as early as the middle of the twelfth century, prevailed in the six- teenth to a degree of which we have happily now no experience, and cannot easily form any clear conception. Small-pox, Scarlet Fever, Measles, and Erysipelas were also then in existence, and often contributed their quota to the frightful mortality of the period. The last attack of Sweating Sickness in England, in 1551, brings us to the middle of the sixteenth century. Towards the end of it we encounter the first of the five epidemics of the Oriental Plague, of which we possess satisfactory accounts. The sanitary history of the last half of the centur}' is Atmospheric Disttir bailees. 8i not without its interest. In the year 1555, for instance, we are told of Febrile Diseases as being prevalent among us — " hot, burning fevers," which, with other strange diseases, ran into the year following, consuming " much people in all parts of England," and proving fatal, between the 20th of October and the end of December, to "seven grave aldermen in the City of London, and among them Sir John Gresham." In 1563 famine and disease destroyed 20,000 people in London j 1565 is marked by a succession of diseases. Small-pox, Measles, and Malignant Sore Throat. In 1574 there was a pesti- lence. In 1577, we have the first distinct notice of the Jail Distemper, of which I shall have much to say here- after, in the notorious Black Assize at Oxford. We have earlier notices of it in 1414 and 1512. In 1583, there was an epidemic dysentery. To pass from land to sea : in 1585, Sir Francis Drake's expedition lost about 700 men, who, for the most part died of calentures. 1586, again, was the date of a great outbreak of the jail distemper at Exeter. In 1 592, as I have just stated, we were visited by the Plague; and the year 1599, ^^^^ ^^ 1^"^^ ^499 of the previous century, was marked by a bad pestilence, of what kind does not distinctly appear. Thus ended this century of epidemics, with its four attacks of Sweating Sickness, as the central figure among the many pesti- lences which scourged our own and other countries. It is impossible to read the history of this eventful •century without being struck with the frequent occur- rence of all those phenomena in the natural world, which tend most to create "distress of nations and perplexity." As we read the pages of Hecker, or such a chronological summary of plagues and pestilences as is to be found in Dr. Short's work, we grow literally bewildered with the repeated references to earthquakes, inundations, droughts, violent storms of rain and hail; comets and fiery meteors j G 82 A Sickly Centnry. to blights, mould spots, blood-coloured rain, fogs and stinking mists, to hosts of caterpillars and swarms of locusts 3 to inverted and distorted seasons, warm winters and inclement summers ; to famines, murrains, and fish rendered unfit for food. Add to these, diseases in so many forms, strange and terrible, the gathering and dis- banding of hosts of mercenary troops, sieges with their inevitable accompaniments of scarcity and disease, battles, with tlieir slaughter and dispersion of sick soldiers to carry disease with them far and wide, and we have a picture of a state of things hard to parallel in any earher or later times. But we must not forget that this century^ if it scourged us with famine and pestilence, and frightened us with earth- quakes and tempests, gave us our English Reformation, our triumph over Spain, and the great names of the Eliza- bethan age. In my next lecture, I shall treat of the Plague. 83 LECTURE IV. THE PLAGUE. The Black Death, or great mortality, of the fourteenth century, was undoubtedly the same disease as the Plague of which I am now to speak, differing only in degree, not in kind. They had contagion for their common property, the bubo for their common sign, a frightful mortality for their common consequence. But as, in the fourteenth century, we had no Bills of Mortality, and no Census of Population, we know nothing of the progress of the disease from week to week, and little for certain of the destruction of life it occasioned. The epidemic of 1499 found us in the same destitution as to reliable facts, and left us in the same ignorance. But the visits of the Plague in the sixteenth and seventeenth centuries were made under more favourable circumstances. London had its weekly Bills of Mortality, and its estimates of population, and these, though imperfect, were an immense improvement on the guesses of the fourteenth century. I shall not now inquire how far facts collected, compiled, and published, as these weekly bills were, are to be rehed upon. I will take the more practical course of using them only for purposes to which I think they are applicable, merely observing, in passing, that, like many other faulty and defective returns, though they may not be strong enough to bear a superstructure of scientific truths, they may yet do good service if we content ourselves with comparing one return with another. This being under- G 2 84 Plague as Affected by Season. stood, I place before me the carefully compiled tables of Mr. Marshall, which present at one view the figures for the five recognised plague-years, 1593, 1603, 1625, 1636, and 1665 5 and I will extract from these figures all the gold I can. Now the first thing I learn from these figures is that, besides the recognised plague-years, there are many others with entries under the head of plague ranging from 1000 to upwards of 4000 in the year j and, in the summer, from 100 to nearly 400 in some weeks. I find such figures in each of the five years 1606 to 1610, and in each of the eight years 1640 to 1647. ^ infer, therefore, that the Plague was not only a destructive epidemic in some years, but a leading cause of death in others 5 and I do not doubt that the disease which the female searchers reported as plague in epidemic years was the same which they returned as plague in ordinary years. Captain Graunt, who made a profound study of the facts relating to the Plague, says of the Plague of 1 603 that it lasted eight years, and of the Plague of 1636 that it lasted twelve years. Of the outbreak of 1625, on the other hand, he observed that the year preceding only 11 died of the plague, and the year following, 134. This, too, is obvious at a glance, that while the wrecks of the winter quarter present many blanks, and those of the autumn quarter a few, those of the spring quarter have four only, and those of the summer none. And this, again, is easy to perceive, that the figures stand thick in summer and autumn, thin in spring and winter j or, to state the matter more exactly, the seasons, in order of mortality, rank thus : — summer, autumn, spring, winter: and I find the same order to prevail in respect of the fatal disease entered as Parish Infection. If now I turn to the five epidemic years, I find that, in them also, the maximum of deaths invariably took place in the summer quarter, and Mortality. 85 in four out of the five towards the end of it j and this is true whether the Plague set in early in the year or later. I now turn to Mr. Marshall's table for information as to the rise, progress, and fall of the five epidemics. In 1593, the first cases (three in number) were registered for the week ending March 14, the maximum (983) was reached in 20 weeks, and in 20 more the number had fallen to 39. The Plague must have reached onward into the following year, but for that we have no returns. In 1603 the first return was for the same week, and for the same number of deaths j but the maximum was not attained till the end of 26 weeks j and at the end of the 40th week, there was a return of 74 deaths. In 1625, the first weekly return was of i death, in the week ending January 3 j the maximum was not reached till the 32nd week ; and, after 18 weeks more, the return was nil. In 1636, the first return was for the week ending April 4 J the maximum was attained after 25 weeks, and, after 12 weeks more, the return is ml. In 1665, the great and final epidemic, the first return is of 2 deaths for the week ending April 25, the maximum was attained after 2 1 weeks, and at the end of other 13 weeks, the deaths were still 281 . So that we must look for a continuance of the Plague far into the next year — the year of the great fire. Let us now compare the figures for these five plague years, and see how many deaths occurred within the years in the winters or springs of which they severally set in. These figures are as follows:— 1593, 11,503 ; 1603,36,2695 1625, 35'4i7 7 1636, 10,400; 1665, 68,596. Hence it appears that the first and fourth outbreaks were the least severe ; the second and third, of about equal, but more than threefold severity, and the fifth and last by far the most fatal. And the five epidemics hold 85 Summary of Facts, the same relative position, if we test their severity by their maximum weekly returns. The figures for the five epi- demics are 983, 3035, 4463, 796, 7165. According to both these tests of severity, the fourth attack, in 1636, was the mildest, the fifth attack, in 1665 (thirty years later), of nearly seven-fold severity. The Bill for 1666 has this very significant entry : — ''In the 97 parishes within the walls of London, from the 19th of December, i66j, to the 28th of August, j666," deaths by the Plague, 284, *' since which time the late dredful Fire hath consumed and laid waste 81 parishes." As up to the end of December the remnant of 16 parishes yielded only 4 deaths, 1994 deaths must have all occurred in 14 parishes, out of the 16 without the walls which the fire had spared, in the 12 out-parishes in Middle- sex and Surrey, and the five in the city and liberties of Westminster. But London does not seem to have been absolutely free of the Plague till the year 1680. I have just said that the fourth attack of plague was the least, and the fifth tlie most, severe. Let it, however, be understood that I have not taken into account that very necessary element in such comparisons, the number of the population. As to the mortality due to the Plague, we must, I believe, rest satisfied with the somewhat rude estimate of Sir Wil- liam Petty, who says " that the plagues of London do commonly kill one-fifth part of its inhabitants." There is one feature of the Plague which I have not yet noticed, and that is its occasional strange fluctuations, or, as Graunt calls them, its '' sudden jumps," " leaping in one week from 1 18 to 927 ; and back again from 993 to 258 ; and from thence again, the very next week, to 852.' From our examination of the Bills of Mortality, then, we have learnt : — Deaths ill the Great Plague of 166^. 87 That in 72 years (from 1593 to 166^) we had 5 out- breaks of the Plague, or about i every 15 years. That these outbreaks continued i, 2, 8, or 12 years. That they began in winter or spring, and reached their climax in summer. That they attained this climax in from twenty to thirty weeks, and passed away or sensibly abated in from twelve to twenty weeks ; so that, speaking roughly, out of live periods of time, three would be taken up in attain- ing the maximum, and two in the fall. That if we place the four seasons in the order of mor- tality, beginning with the highest, they stand thus : — summer, autumn, spring, winter. That if we measure the severity of the live outbreaks by the deaths in the year in which they set in, or by the greatest number in any one week, but taking no account of population, the hrst and fourth were least severe, the second and third more severe, and the fifth the most fatal, both absolutely and relatively to any possible increase of population. That the mortahty due to the Plague may be taken at one-fifth of the inhabitants. Let us now turn to the facts recorded for the year of •the great Plague, 1665, and see whether we can learn any- thing more by studying them. We have already seen that the Plague lirst showed itself on the 25th April by two deaths, that it attained its acme, September 19, when it claimed 7165 victims; that by the end of the year the deaths had fallen to 281 ; but that, though the great fire of the year following destroyed no less than 8 1 parishes within the walls and 2 without, 1 998 deaths occurred in that year, and that even then it was not extinct. If we count all the deaths from its outbreak in 1665 to its final disappearance, we have a grand total of 70,676. 88 The Deaths ill \66^ underrated. o But I believe this by no means represents the fall severity of the epidemic ; for I find that, when the deaths due to- the Plague are taken away from the total deatlis of the year 1665, there remains a number of deaths little short of 10,000 in excess of the deaths for the previous year (itself the most fatal to life of a long series). These deaths in excess I attribute with great confidence to the- Plague J for I see in the way the epidemic was dealt with,, and especially in the harsh measure which caused infected, houses to be shut up, the strongest possible temptation to- set down to other causes the deaths due to the Plague. And this conviction is strengthened if I examine the causes in detail. Thus, I find an excess of 1813 over the previous year under the head of spotted fever, of 1299. under that of ague and fever, and of 130 under sucb headings as imposthume and abscess, sores and ulcers. Then fright and grief figure for 117 deaths. Even con- sumption, a most uniform cause of death, shows an im- possible increase of 1 1 6^,, and surfeit (whatever that may mean) of 1007. Take all the entries in excess under the heads of diseases that attack adult men and women,, and they yield a total of nearly 8500. The otlier items of increase are very interesting. More women died in child-bed, or suffered abortion by 469 f. and more children perished by teething, convulsions,.. rickets, and canker, to the number of 1670. This last number in part represents an indirect consequence of plagues and pestilences, and indeed of all deatlis and diseases among young adult women ; I mean the neglect of infants and young children. This is the educational* aspect of Plagues and of Preventible Diseases. May we not, then, take credit for something short of 1 0,000 extra deatlis ; at least for such a number as will raise the 70,676 deaths by Plague to 80,000? I think we may.- I now turn for a more exact account of the Plague of Rise and Progress of the Plague. 89- 1665 to the work of Dr. Nathaniel Hodges, a Fellow of the College of Physicians, resident in the City, and as his book shows, in active practice among the victims of the disease. Dr. Munk, in his Roll of the Royal College of Physi- cians of London, says that he " acquired a great name, among the citizens of London, that he remained at his post and continued in unremitting attendance on the sick," and that, '^ during the latter part of his life, he received a regular stipend from the City of London, for the performance of his charitable office." Dr. Hodges tells us that about the close of 1 664, two or three persons died suddenly with symptoms of the Plague in one family at Westminster, that some timid neighbours of theirs took fright and removed into the City of London, carrying the taint of the pestilence with them J whereby the disease, which existed only in a family or two, gained strength, and spread abroad 3 and '^ for want of confining the persons first seized with it, the whole city was in a little time irrecoverably infected." In December a hard frost set in, which lasted three months, and during that time very few died of the plague. But the disease was not extinguished j for in the middle of the Christmas holidays, the doctor was called to a young man in a fever, who after two days '' had two risings about the bigness of a nutmeg," " one on each thigh," with a "black hue " and a *' circle round them." By these and subsequent symptoms, he judged it to be a case of Plague. It did not prove fatal. When the frost broke, the disease gained ground, and extended into several parishes ; and the authorities issued an order " to shut up all the infected houses," so as ta prevent ingress and egress. To give effect to this order, the houses of the infected were to be marked with a red cross, and to carry the inscription, " Lord liave mercy upon •90 The College of Physic ians. us ;" and a guard was set, whose duty it was to hand food and medicine to the sick, and to prevent them from going abroad till forty days after their recovery. In spite of these harsh measures, " the Plague more and more increased." Nor will this surprise us if we imagine the frantic and successful etforts that must have been made by the non- infected to escape, and the temptation to servants and nurses to appropriate and remove the property of the dying and dead. Indeed Dr. Hodges accuses the nurses of strangling their patients, and secretly conveying the pestilential taint from sores of the infected to those who were well 3 and he justifies his accusation of " these aban- ■doned miscreants," the Gamps and Prigs of the seven- teenth century, by two instances 3 the one of a nurse who '' as she was leaving the house of a family, all dead, loaded with her robberies, fell down dead under her burden in the streets," the other of a " worthy citizen," " who being suspected dying by his nurse, was before-hand stripped hy her J but recovering again, he came a second time into the world naked." In spite of the well intentioned measures of the autho- rities, the Plague continued through May and June with more or less severity, sometimes in one place, sometimes in another, till the people, becoming thoroughly frightened, flocked out of town in crowds. But the disease raged with redoubled fury among those that remained. Then the authorities bestirred themselves to the utmost. They instituted a monthly fast ; and the King commanded the College of Physicians " to write somewhat in English," that might serve as '"a general director)^" The College not only obeyed the royal commands, by inventing a " Plague IVo.ter,'' consisting of a cordial distilled off from a vinous infusion of a score of very harmless roots, leaves, and flowers, but also appointed two of their number to co- operate with two chosen from among the aldermen in at- Ravages of the Plague. tending the intectecl j while Dr. Ghsson, Regius Professor at Cambridge, and Drs. Paget, Wharton, Berwick, and Brookes volunteered their help, with many others who survived, and eight or nine who fell victims to their self- devotion, among whom Dr. Conyers receives honourable mention. Still, in the face of every precaution, the Plague con- tinued its work of destruction, especially among the com- mon people, so as to be called the " Poors Plague ;" and, in August and September, completely got the mastery, " so that three, four, or five thousand died in a week, and once 8000." And here I will follow Dr. Hodges' example ; and try to give you some idea of the state of things then pre- vailing. But, in doing so, I must shorten and tone down his description. "In some houses," he says, "carcases lay waiting for burial," " in others, persons in their last agonies." " In one room might be heard dying groans, in another the ravings of delirium," and, near at hand, relations and friends bewailing their loss and their own dismal prospects. " Death was the sure midwife to all •children, and infants passed immediately from the womb to the grave." Some of the infected ran about stagger- ing like drunken men, and fell down dead in the streets, or they lay there comatose and half dead j some lay vomiting as if they had drunk poison ; and others fell dead in the market in the act of buying provisions. The plague spared " no order, age, or sex." The divine was taken in the very exercise of his priestly olfice, and the physician while administering his own antidote ; and though the soldiers retreated, and encamped out of the city, the contagion followed, and vanquished them. Many in their old age, others in their prime, most women, and still more children, perished, " and it was not uncommon to see an inheritance pass successively to 92 Decline of the Plague. three or four heirs in as many days." There were not sextons enough to bury the dead, the bells ceased tolling, the burying places were full, so that the dead were thrown into large pits, dug in waste ground, in heaps, 30 or 40 together j and those who attended the funerals of their friends one evening, were often carried the next to their own long home. This is written of a time when the worst had not yet happened. It was about the beginning of September that the disease was at its height. Then fires were ordered to be burnt in the streets for three days together; but, before the time had expired, they were extinguished by heavy rains, which ushered in the most fatal night of all, with its register of more than 4000 deaths. From this, its culminating point, the Plague, " by leisurely degrees declined," " and before the number in- fected decreased, its malignity began to relax, inso- much that few died, and those chiefly such as were ill- managed." Dr. Hodges distinctly states that the pesti- lence did not stop for want of subjects, but from the nature of the distemper. "Its decrease was, like its beginning, moderate." Early in November, people grew more healthful, and though the funerals were still fre- quent, " yet many who had made most haste in retiring, made the most to return j" " insomuch that in December, they crowded back as thick as they fled." The houses were again inhabited} the shops re-opened ^ the people went cheerfully to their work 3 the rooms, in which a short time before infected persons had breatlied their last, were peopled afresh, and many went into their beds " before they were even cold, or cleansed from the stench of the diseased.'' " They had the courage now to marry asrain," " and even women, before deemed barren, were said to prove prolific, so that, although the contagion had carried off, as some computed, about 1 00,000, after a few The Plague at Eyam. 93 months, their loss was hardly discernable." But the next spring there appeared "some remains of the contagion," which was easily conquered by the physicians ; and the whole malignity ceasing, the city returned to perfect health, as, after the great lire, " a new city suddenly arose out of the ashes of the old, much better able to stand the Jike flames another time." So much for the Plague in London. But the city became the focus of " infection to surrounding districts, and, even, as I shall presently show, to remote places. We are told that the citizens who crowded into the adjacent towns, carried the infection with them, so that the Plague reigned over whole counties, leaving hardly any place free, attacking with extreme violence the towns on the Thames, not even sparing places " of the most advantageous situation for a wholesome air." It was not, as Hodges thought, the fault of the moist air of the river, but of the tainted goods that were carried upon it. I have just stated that the Plague was conveyed from London even to remote places. I may add that it was not by personal intercourse only, but also by goods and merchandize. Of this latter mode of communication, we have an admirable and most instructive example in what befell the inhabitants of Eyam, in Derbyshire, a place rendered for ever memorable by the heroism of its rector, Mompesson. Eyam, a hamlet secluded among the hills of the Peak of Derbyshire, is about 150 miles from London, and had a population of 350 souls. Quite early in the month of September, when the Plague was at its worst in London, there was sent from London to one George Vicars, a tailor, a box of clothes. He opened the box, and hung the clothes to the fire j and, while he watched them, was suddenly seized with violent sickness, and other alarming symptoms. On the second day he was worse 3 was deli- 94 Alovipesson. rious at interv als, and large swellings appeared on his neck and groin. On the third day, the plague spot was on his breast, and he died the following night, the 6th of Sep- tember. The disease spread from this centre j by March ist, 1666, had destroyed 58 souls 3 and, by the beginning of June, 77, or more than one in live of the population. About the middle of June, the Plague began to increase j. and then it was that Mrs. Mompesson, the rector's wife, implored her husband to remove, with herself and their two young children, from this doomed village. But he, alleging his duty to his suffering flock, and his responsi- bility to his Maker, and pointing out the stain which would rest on his memory did he desert his post in this hour of danger, determined to remain. He, on his part, tried to persuade his wife to take their children with her to some place of safety till the Plague should be stayed. But she declared that nothing should induce her to leave him alone amidst such ravages of death. Her children, however, she would send away. It was at this time (about mid June) that the inhabitants, wishing to follow the example of the few wealthy who had left early in the spring, and of a few others who had built huts for themselves in the neighbourhood, would have deserted the village en masse. But now Mompesson, with his own example, and that of his wife to back him, pleaded so effectually the selfishness, and the uselessness of such a course, the danger to the neighbourhood, the slight chance of profit to themselves, that the inhabitants were induced to give up all thoughts of flight. Mompesson, then, con- certed measures with the Earl of Devonshire, \\ho re- mained at Chatsworth during the Plague, and with his assistance established and carried out an efficient qua- rantine. A circle was drawn round the village, at a distance of about half a mile, bevond which no inhabitant should Frightful Mortality. 95 pass ; and to two or three chosen spots_, provisions were brought every morning, by persons from the neighbour- hood, who immediately retired. Men, appointed by the rector, fetched these provisions, and left the purchase- money for the few articles not given by the earl, in troughs of water. Tow^ards the end of June, " the plague began to rage even more fearfully." There were so many deaths^ that the passing bell was no longer rung, the churchyard was no longer used for interment, and the church-door was closed. The rector read prayers and preached from an arch in an ivy-mantled rock, in a secluded dingle, to his. people seated on the grass at some distance from each other. All this time, though Mompesson had been visiting from house to house, he and his wife had escaped. But on the 22nd of August Mrs. Mompesson was seized, and three days after was at rest in the village churchyard. In this terrible month of August there were 77 deaths out of a population of less than 200 remaining at the begin- ning of the month. At least 2 in ever}' 5 must have died. The hot month of September proved less fatal 5 and on the nth of October the Plague, as if exhausted with ex- cessive slaughter, held its hand. It had attacked 76 families, and swept avi'ay 267 out of about 350 in- habitants — say 7 in 9. These are the figures taken from the parish register. Mompesson states the deaths at 259 ; it is likely, therefore, that 8 died from causes other than plague. The 267 deaths were distributed thus : males, 1365 females, 1265 infants, 5. We are not told of the number of attacks that did not prove fatal j but we know that Mompesson's man-servant, and one Marshall Howe, a sturdy daring giant who acted as gravedigger, had the plague and recovered. <)^ End of the Plague at Eyam. In Wood's " History and Antiquities of Eyam," the names and dates are carefully extracted from the register j so that we can follo\\^ the Plague by the month and by the week. It lasted thirteen months, from September 7, 166^ to October 5, 1666. In the first month it claimed •6 victims j in the second 23 ; then for seven months, till the end of May, 1666, it never killed more than 9, and in May as few as 4. In June it resumed its activity, claim- ing 19 victims; in July the number rose to 56; and in August, when it reached its chmax, to 77. l\\ September, there was a somewhat abrupt fall to 24 ; and in October {when 10 deaths were entered without dates) to 14. I have extracted the deaths according to the names and order of the deceased, and find under the same names cases of 8, 10, II, 13, and 14 deaths; and, as showing their quick succession in some instances, such figures as these : in a family of Rowes, the 41st, 42nd, and 43rd interments. I find, too, that the second death occurred in the family of the reputed landlord of Vicars, and the third in the house of the next neighbour. If we count by weeks, we attain the climax about the 44lh week, when there were 26 deatlis : but its history, both by weeks and months, is one of slow increase at first, of decided progress during the month of October, of a comparative inactivity during seven months of winter and spring, of progressive and rapid increase in the five months of summer and autumn — evidently at Eyam, as in London, a disease much promoted by heat, and greatly checked by cold. Mompesson, the hero of this sad tragedy, left Eyam in 1669, three years after the Plague had ceased, for a living in Nottinghamshire, where, so fearful were the people •even then of the Plague in which he had lived and worked so long, that he was obliged to live in a secluded hut till their fears had died away. Episodes of the Plague. 97 With this tragedy of Eyam are associated two episodes relating to the Talbots and Hancocks, who found their place of interment in the Riley graves. Riley was in an airy situation, a full quarter of a mile from Eyam. On the 5th of July, after the Plague had been in Eyam ten months, Bridget and Mary, daughters of Richard and Cathe- rine Talbot, died, and were buried by the father close to the house. On the 7th he performed the same sad office for his surviving daughter Ann, and on the i8th for his wife. His son Robert died on the 24th 5 the next day the father followed j and on the 30th another son, the last sur- vivor, who is believed to have been buried by the Han- cocks, whom the pestilence then seized. On the 3rd of August John and Elizabeth Hancock died, and w^ere buried near their cottage by their mother ; four days later she interred her husband and tw^o other sons. Two days more, and she was digging the grave of her daughter Alice ; yet another day, and Ann, her only surviving child left at home, died and was buried. A few days after this Mrs. Hancock left her desolated home to spend the rest of her sorrowful life with her only surviving son. He erected the ''Riley Graves," on which the particulars of this ter- rible history are engraved. In Wood's work there is the record of a case very like those of the Talbots and Hancocks. It belongs to the Plague of 1625, and occurred at Bradley, in Cheshire. Thomas Dawson, of Bradley, his wife, brother, three sons, a daughter, a man-servant and a maid-servant, died of the plague brought from London, a distance of 1 70 miles, by one of the sons. The deaths all took place, and the burials are recorded in the parish register, in the interval between July 25 and September 5, a period of forty-two days. These nine persons seem to have made up the whole family. Of Richard Dawson, the uncle, it is alleged that, being a heavy man, and sick of the plague. 98 Antecedents of the Plague. he got out of bed, dug his own grave, caused some straw to be thrown in, lay down in it, had his clothes placed over him, and so died. The history of the " Plague of Eyam" has pathetic passages and images of horror, such as the last walk of the rector and his wife through the fields, when, talking on their usual theme, their absent children, Mrs. Mom- pesson marks, to the terror of her husband, the sweet smell of the air 3 or that picture of poor Mistress Hancock, dreading to touch the dead bodies of her husband and sons, but tying a towel to their feet, and so dragging them to their last resting place. It is not, how- ever, as a romance of heroic self-devotion that I have been describing the Plague of Eyam, but as an authentic example of plague transported by clothing, infecting a whole village, and being restricted to it and its immediate neighbourhood by judicious and efficient measures of quarantine. I may mention, in passing, that Dr. Mead, writing in 1722, notices the plague at Eyam, and gives a brief history of it, for which he says that he was indebted to the then rector, the son of Mompesson, and another worthy gentleman. From Eyam and Mompesson let us now return to London and Dr. Hodges, and see what he has to teach us about the antecedents of this Plague of 1665. Let us first inquire whether there was anything in the year or times preceding the attack to account for the great destruction of hfe it occasioned. Did famine or scarcity, the precursors of so many other pestilences, usher in this also ? Was there such a want of fruit and vegetables as, by inducing scurvy, or a scorbutic condition, would make men easy victims to the disease? The answer is conclusively in the negative 3 for Dr. Hodges tells us that ihe necessities of the poor who were left Contagion. 99 behind were relieved " with a profusion of good things from the wealthy, and their poverty was supported with plenty j" that there were open markets and a greater plenty than usual of all provisions, " so that there was the reverse of a famine 3" and we are further told that "this year was luxuriant in most fruits, especially cherries and grapes, which were at so low a price that the common people surfeited with them." Of vegetables no special mention is made. These statements are confirmed and amplified in another passage. ** Had we," he says, " any famine before the last sickness ? or had we portentous swarms of insects like clouds over us ?" No, just the contrary 3 " all things from nature were promising and serene." The only exception I can find to these state- ments is in a passage where the Doctor says that in the year before the Plague "■ there was a great mortality amongst the cattle, from a very wet autumn, whereby their carcases were sold amongst the ordinary people at a very mean price j" but he rightly thinks that a cause so private and particular could not be supposed to extend to so universal an efifect. Of any special over- crowding, or unusual neglect of cleanliness in the time preceding the plague no mention whatever is made. In this great pestilence, therefore, we wholly miss the most common and eflScient predisposing causes. As to the exciting proximate cause we are not left in doubt. Dr. Hodges, at least, has no misgiving about it. It was contagion and nothing but contagion. We have it, he tells us, *' from the most irrefragable authority," that the Plague "was imported to us from Holland, in packs of merchandize;" and "by common fame" " it came thither from Turkey in bails of cotton or silk." Dr. Hodges deals with the anti-contagionists of his day in this passage. The plague is communicable by contagion, and in " that way only," "killing most it seizes," and "the infection H 2 loo Syinptojus. of the pestilential poison is not only transferable from one subject to another, either by mediate or immediate contact," "but all the conditions hkewise of its exertion are as conspicuous as the noon-day sun j wherefore those arguments to prove the pestilential corruption not to arise from contagion are trifling and not worth notice, aS' altogether disconsonant to reason and experience." That our author, though he expresses himself in terms Strange to us, had yet a \try clear view of the whole matter of causation I infer from his enumeration of the four things chiefly necessary to a contagion. There is, first, " an efflux of the contagious seminium/' secondly, " a convenient medium for the contagious particles to move through and be conveyed by 5" thirdly, " a fitness in the subject to receive and cherish tlie contagious f^wi'ia;" and fourthly, **a due stay of this seminium." Of the semiiiium, or matter of contagion. Dr. Hodges does not pretend to have any knowledge j but he dis- credits those who allege that the infection resembled *•' the fragrancy of flowers in May," or, " the stench of a rotten carcase." I may, however, remind you that it was his wife's exclamation — "how sweet the air smells" — that struck terror into the heart of the brave Rector of Eyam. Is it not possible that an illusion of the sense of smell may have been sometimes a sign of seizure, as it is occasionally of a fit of epilepsy r In describing the symptoms of the Plague, Dr. Hodges distingnishes such as are signs of infection from such as belong to the fully formed disease. The early symptoms were shiverings, vomiting, giddiness, headache, delirium, and drowsiness — symptoms common to most severe febrile attacks. The more advanced symptoms were fever, restlessness, great heat at the pit of the stomach, palpitation, and bleeding at the nose. Characteristics of the Plague, ' loi The characteristic symptoms were the appearances on the skin, known as Blains, Buboes, Carluncles, and Spots, and certain marks called Tokens. The fever, in some cases, was continued, in others, re- mitient, m oth^va, intermittent ; often attended with in- tense thirst, and a dry, black tongue. The matters dis- 'Charged by sweat and urine, by vomiting and purging, were often intolerably offensive. Delirium seems to have been very common, for Hodges says, " all the sick," ^'quickly after seizure, grew delirious, running wildly about the streets, if they were not confined by force." A severe dysentery was present in some cases, and blood was poured out under the skin in more. Sudden death without warning, deep sleep passing into death, death in a few hours after the appearance of the characteristic signs — such were some of the exceptions to the rule. Our author seems to have been a close observer of the blains, buboes, carbuncles, petechia?, and tokens •which were the outward and visible signs of the Plague. The Blains were blisters, from the size of a pea to that •of a nutmeg. They began with a sharp, shooting pain ; contained a thin, straw-coloured liquid j burst and dis- charged a corrosive liquid, yellow or black, and were surrounded by a circle, red at first, variegated afterwards. They appeared in many parts of the body, and their number varied in different cases. One woman was covered all over with them. Sometimes they were the first indications of infection, rarely they became inflamed and turned to carbuncles. The Buboes were hard, painful tumours, inflamed and gathering behind the ears and in the armpits or groins j one or two, in favourable cases, very many in unfavour- able ones. There might be one in the right arm-pit, another in the left groin. They would sometimes vanish. I03 TJie Tokens especially during a sweat 3 or they would come and go j. or they would suppurate. The Carl'uncle began as a llain, which, when it broke^ became covered with a dead crust, or eschar, round which the skin first grew red, then livid, at last black. They might appear anywhere — breast, finger, armpit, groin > two, three, or more at a time ; and the matter from a carbuncle would produce another on any part that it touched. The petechice were little deep-coloured spots on the skin, like flea-bites without the central spot, not removed by pressure, not large and ditfused like scur\'y spots, and showing themselves chiefly on the neck, breast, and back, not on the arms and legs. These spots, too, were few or many 3 might be red, yellow, purple, or black j might cover the whole body 3 might come and go, and be carried otf by a sweat. The tokens were deemed the " pledges or forewarnings of Death." They were " minute and distinct blasts,'' or blisters ; but they might look like warts. They might be small as a pin's head, or large as a silver penny. They rose up " with a little pyramidal protuberance," from which they spread 3 appeared on the internal parts as well as on the skin j were sometimes hard, sometimes soft, sometimes sensible to the prick of a needle (a good sign), sometimes insensible (a bad one). They were bad signs even when every other symptom seemed favourable 3 and, especially ivhen deep, were " the sure and speedy messengers of deathy Here are two cases in point : — A girl, when first seized, breathed easily, had a natural warmth of surface, an equal and regular pulse. All things were ''' genuine and well" with her, "as if she had ailed nothing." Dr. Hodges was even inclined to think her shamming, until, on examining her breast, he found " the certain characters of death imprinted in many places,'" Remedies — Virtues of Sack. 103 and the following night, ''before she herself, or any person about her, could discern her otherwise out of order," she died. The doctor had seen a widow of sixty eating a hearty dinner of mutton and broth j she said of herself that she had "never been better in her lifej" but he found her pulse to intermit, and, on examining her breast, he found "an abundance of tokens." She died that evening. These details will suffice, I think, to give to all men, but especially to doctors, a lively idea of the fatal pesti- lence of 1665, and of the Plague in all its out- breaks. In the matter of treatment^ Dr. Hodges shows himself a man of sense. He speaks doubtfully of bleeding, but denounces large and repeated venaesections, deeming it madness " to sink the necessary strength by a rash effusion of blood," " in order to remove an imaginary fulness," and he says that he had "many times seen the blood and life drawn away together." But he commends the J^ir- ginian Snake Root, and Ginger and Spirits of Hartshorn given in the Plague Water of the College of Physicians (a spirituous cordial, as you may recollect) ; but, above all, he gratefully extols " the virtues of sack,'' in which he seems to have been somewhat of a connoisseur, preferring as best that which is " middle-aged, neat, fine, bright, racy, and of a walnut flavour." This generous liquor is both antidote and remedy, unless for those who use it " too intemperately." Of other remedies then in repute he speaks with very creditable reserve. Of the virtue of the powder of an unicorn's horn, he is as doubtful as of the existence of the creature itself 3 but he does not condemn troches of vipers, or their volatile salt ; and he found greater success with troches made of the flesh of the rattlesnake than from the native product. As he commends the native remedy 104 Preservation from a Pestilence. for its cheapness, vipers must have abounded in those days. But these, as well as the ''manifold compositions,'' which must have indeed consisted of many elements, if they were more complicated than the Plague water of the College, or his own alexipharmick vinegar or anti-pestilen- tial confection, were innocent enough compared to what I may call the regimen of the sick-room j and the same may be said of such local applications as the flesh of pickled herrings to the feet and wrists, and of the bare rump of a fowl, live pigeons, and warm sheep's lights to draw out "the pestilential venom'' from the boils and carbuncles. What I have called the regimen of the sick-room consisted in keeping the infected close in their beds the whole time of the disease (tying them in their beds, if delirious) ; keeping the patient forcibly awake, if drowsy ; covering him witli blankets to make him sweat ; scrupu- lously avoiding change of body-linen and bed-clothes, because, forsooth, ''the patient takes harm by clean coverings," and incurs "the approach of air" by tlie shitting, because also the fresh things are apt to be damp. The soap used in washing the clothes he acquits of mis- chief, in which he differs from Diemerbroeck, the Dutch- man. In treating of " Preservation fro/n a Pestilence," Hodges also shows himself a man of sense. He would make a timely separation of the infected from the healthy, would forbid public funerals, and all kinds of meetings, and would enjoin quarantine ''according to the custom of trading nations.'' He approved the action of the magis- trates in appointing two in every parish to pay a daily visit to every family and see whether they were free from the infection or not. Having noted the good effect of brisk winds, he would stir the air by " the frequent ex- Amulets and Charms. plosions of great guns, especially morning and evenings" and he thought that the products of combustion of " an intimate combination of nitre and sulphur " greatly altered ''the saline qualities of the pestilential taint." Hence he approved of fumigation with nitre and resinous woods. He most approved the placing of a chafing-dish in the middle of a room, or in the doorways or win- dows, and burning in it what he terms "proper things,^' viz., quick lime thrown into an aromatic liquid, or a pas- tile made of a pound of saltpetre and three ounces of sulphur, melted with benzoin and storax, in quantity sufficient to make, when dried, a suitable mass. This is perhaps his best receipt : " The streets, sinks, and canals should daily be cleared of all filth ; because stench and nastiness are justly reckoned entertainers of infection." "Dogs, cats, and other domestic brutes," as carriers of contagion, should be killed. He also shows a proper respect for cleanliness as a measure of prevention, though his treatment of the infected did not, as I have shown, tend to promote it. He says, " I know not, indeed, a greater neglect than in not keeping the body clean, and keeping at a distance everything superfluous or offensive." Lastly, fasting was to be avoided, a diet nourishing and easy of digestion to be chosen, with pickles and sauces, juice of sorrel, lemons, oranges, pomegranates, barberries, and sack at every meal. Tobacco, much praised by Diemerbroeck and others, he does not approve, alleging against it its narcotic qualities, its poisonous oil, its pro- motion of spittle, and " the irksomeness of its scent." He is its ''professed ewew?/," and preferred sack, in which (though a moderate man myself) I confess that I heartily agree with him. He greatly commends a mixture of which camphor is the active ingredient. The common people, in Hodges's day, were much addicted to amulets and charms. They painted their ic6 Hodges Management of Himself , bodies with hieroglyphics, and carried about their persons a walnut filled with mercury, a paste made with arsenic, or a dried toad 3 and some nasty old nurses gave human excreta as antidotes. The arsenical paste, in the case of an elderly lawyer, seems to have determined the spot for a " pestilential carbuncle," and in other instances gave rise to large blisters. Dr. Hodges finishes his history with a curious account of the regimen he adopted for himself. He kept open an issue which warned him, by a shooting pain and an ill- conditioned discharge, when he ought to have recourse to alexipliarmics, or poison-antidotes. As soon as he rose in the morning he took his own Antipestilential Electuary (which, like the Plague water of the College, consisted of a score of harmless simples) to the size of a nutmeg. He then despatched his own private concerns -, and this done, went into a large room, where he spent two or three hours, as in an hospital, among crowds of citizens, some with the first symptoms of the Plague, others convales- cent. This work done, he took his breakfast, after which till dinner time, he visited the sick at their own houses. When he entered them, he caused " some proper thing " to be burnt on coals, and kept in his mouth some lozenges while he examined the sick. He took care not to enter the sick-room sweating or panting, and he kept his mind as composed as possible. After some hours he returned home, drank a glass of sack, eat a nutritious meat dinner with pickles, and finished with more wine. Then came many more persons for advice, and further visiting of the sick till eight or nine at night. And he " concluded the evening at home by drinking to cheer- fulness of his old favourite liquor, which encouraged sleep, and an easy breathing through the pores at night." If, in the day-time, he had what he deemed " the least approaches of the infection," such as giddiness, nausea. Efficacy of Isolation. 107 and faintness, he immediately had recourse to a glass of sack. Yet, in the whole time of the Plague he found himself ill but twice, and soon got better. He is said (probably on the strength of this statement of his) to have had the plague twice. But this, I think, is a mistake. Such, then, is a faithful account of the Plague of 1665, from one who was an eye-witness from hrst to last 3 a well- informed, sensible, industrious, and brave man. I should not have allowed a disease that has not been seen in England for two centuries to take up so much of our time were it not that it has visited France, Russia, and our own possession (Malta) in much more recent times. It attacked Marseilles in 1720, Moscow in 1771, Malta so late as 18 13 5 and, in each of these cases, after an in- terval which might well have filled the inhabitants with the confidence that they had seen the last of it. It had not been in Marseilles for 70 years 3 in Moscow for a century and a half 5 in Malta for 137 years. We are not justified, then, in asserting that England and London can never again be visited by this formidable disease. I will there- fore ask you to give such further attention to this subject of the Plague as this consideration seems to warrant. We have in it a good example of a contagious fever, with buboes and carbuncles for its local expression j of a specific poison seeking its elimination from the system in the skin and lymphatic glands. I speak of the disease as contagious because I find the facts conclusive on that point, and the arguments of such men as Gooch and Robert Williams convincing in the face of the few who have broached the opposite doctrine. I adopt as probably true the estimate of Dr. Williams that the infection may lie dormant, or latent, for as many as twenty-one days. I am also con- vinced, by the facts recorded by competent and trustworthy authorities, that whole communities and bodies of men, by perfect measures of isolation, have kept free from the o8 Sanitary Measures. ■disease, or (as in the case of the village of Eyam) have prevented it from spreading to their neighbours. These (as I think) are the well-established facts and principles with which sanitary science has to deal j and the question naturally arises, What demand may be made on our knowledge and skill by this or any similarly con- tagious malady ? Now, we may have to advise and to act in three diffe- rent contingencies : — i . The Plague may have made its appearance in some city, as in London, in 1665. 2. The Plague may be known to exist in some country with which we have commercial relations. 3. The Plague may have shown itself in Egypt, or some neighbouring country, from which, as in times past, it may threaten to spread. I. In the first case — that of the Plague having broken out in some city, such as London — it is evident that we could not recoinmend the cruel expedient of barricading the doors and windows of infected houses, and leaving their inmates to perish j nor could we, in these days, shut up the infected houses, mark them with a red cross and a prayer, confine the healthy in the same atmosphere with the sick, and prevent ingress and egress by a guard, as was done in London in 1665. But what we could do, and what we should be bourd to do, would be to appoint skilful and active persons in every parish or district, as it became infected, charge them to make a daily house to house visitation, to examine the sick, and if they were found with the marks of the plague upon them, isolate them to the utmost practicable extent in the houses in which they had fallen sick, or have them removed to some pest-house j and in any case provide for the destruction or purification of clothing, bedding, furniture, and houses, and the immediate disinfection of every matter discharged from the person. Water supply, ventilation, drainage, and the speedy removal of all offensive matters, should Quarantine. 109 receive prompt and special attention j and proper food and medicines should be liberally supplied. In a word, each case as it arose ought to be promptly taken in hand and isolated from the healthy to the utmost extent consistent with the proper treatment of it ; while every known sanitary precaution should be taken to destroy the con- tagious matter as soon as formed. 2. On the second supposition — that the Plague existed in some countr)-- with which we have commercial relations — we might be required to advise the Government as to the expediency of establishing a quarantine, with its necessarily complicated machinery. At present I will only remark how troublesome and costly an interference with com- merce this measure implies j how sore a temptation there must be to evade it 3 how hard it is to give to it full prac- tical effect. But, on the other hand, how grave a respon- sibility must that government incur which, with the terrible histories of past plagues before it, and the fact of contagion admitted by the best authorities, should deter- mine to abandon so obvious a precautionary measure. Let us hope that the knot of this dilemma, so hard to untie, may some day be cut by our experience of the efficacy of house to house visitation and prompt treatment, sanitary and remedial, of each case as it arises. 3. On the third supposition — that, namely, of the Plague showing itself in Egypt, or other less common birth-place — it is obvious that the governments of the countries threatened with infection might fairly insist on every known precaution being taken to limit the disease ta the first cases that show themselves 3 and (what is still more important) on the towns and districts where the Plague is known to prevail being brought into and maintained in the best possible sanitary condition, like precautionary measures being adopted in reference to such occasional gatherings of human beings as war and pilgrimages imply. no LECTURE V. FROM THE GREAT FIRE TO THE CLOSE OF THE EIGHTEENTH CENTURY. We are now come to our third sanitary epoch, extend- ing from the Fire of London in 1666, to the end of the eighteenth century. It may be conveniently subdivided in to three periods, of which the first extends from the Great Fire to the end of the seventeenth century 3 the second and third embracing the first and second halves of the eighteenth. For our knowledge of the prevalent and fatal diseases of this period of nearly a century and a half, we are indebted to the writings of physicians practising in London, and to the London Bills of Mortahty, taken in conjunction with what history teaches us of the results of the Great Fire, and of the progressive changes brought about by increasing wealth, extended commerce, and im- proved habits of living. In treating of the first period of thirty-four years we must begin with the Great Fire and the immediate consequences that flowed from it. It broke out on the night of Sunday, September 2nd, 1666. It began on Fish Street Hill and continued to burn " for several days together, till it had consumed everything, from the Tower to Temple Bar." It destroyed 81 out of the 97 parishes within the walls, and 2 of the 16 without the walls. It found the Plague still in possession of the city, though in a very subdued form. The year previous it had swept away nearly 70,000 inhabitants, probably Our Streets and Houses. 1 1 1 80,000, possibly more. This year of the Fire 288 only died of it in the 97 parishes within the walls, 574 in the 16 parishes without the walls, 939 in the 12 out-parishes in Middlesex and Surrey, and 197 in the 5 parishes in the City and Liberties of Westminster 3 in all 1998. Now of this number there died between the Fire in September and the end of the year, 4 in the 16 parishes remaining within the walls, 73 in the 14 left standing without the walls, and a number which I am not able to ascertain in the out-parishes of Middlesex, Surrey, and Westminster. But if the deaths in these out-parishes after the Fire bore to the whole number for the year the same proportion as they did in the parishes without the walls, namely i to 8, we should have to allow about 142 deaths j which, added to the other ligures, would give a total of deaths from the Plague, in the year after the Fire, of 219. At any rate, the Plague must be understood to have survived the Fire in the parts of London which were not burnt. The year following (1667) the Plague is still credited with 2,^ deaths, and in the subsequent years with 14, 3, o, 5, 5, 5, 3, I, 2, 2, 5, and 2, this being the number for 1 679, the last year in which any entry under this head appears. Now let us inquire what sort of a city this was that the Plague haunted and the Great Fire consumed. It con- sisted, as we learn on good authority, of narrow, crooked streets, many of them unpaved, with drains all above ground, and sewers much neglected, with a very insuffi- cient supply of water. The houses were of wood, lofty, dark, and ill-planned, each storey overhanging the one below J at the same time that enormous sign-boards swung across the street. In this way effectual provision was made against the intrusion of two of the great purifiers, fresh air and sunlight. The inside of the houses was in keeping with the out. The floors, often of clay, were strewed with rushes, or in the case of such grand struc- 112 London Improvements. tures as the palace at Greenwich, with hay j and we learn from the letter of Erasmus, to which I have already re- ferred, that in the days of Cardinal Wolsey, though fresh rushes were supplied from time to time, there would re- main, sometimes for twenty years together, a substratum of the most nauseous and disgusting description. And it appears from earlier accounts, and from certain civic restrictions and regulations, that this loathsome mess was at length turned out into the narrow streets, to be consumed by dogs, cats, pigs, and poultry, or imperfectly washed away by the rain. That this is no exaggerated statement we may infer from the improvements made and regula- tions issued after the Fire. The streets were widened and levelled for the more free flow of the waters, and the sign-boards were ordered to be fixed against the houses ; proper places were selected for lay-stalls j cess-pools were made at the grates of the sewers to receive sand or gravel and prevent choking j the *' Fellowship of Carmen " were to cleanse the streets from *' dung, soil, filth, and dirt," and persons were forbidden to lay in the streets any dead ani- mals, offal, or " noisome thing," or to feed kine, goats, hogs, or poultry, in the streets, or to cast any carrion, putrid flesh, rotten vegetables, rubbish, or dung, into the ditches or sewers, grates, or "gullets." And lastly, the offensive refuse of the houses was not to be run off into the drains or common sewers. The regulations for street cleansing had been rendered doubly necessary by the destruction of 40,000 dogs and five times as many cats, which had acted the part of scavengers, with the serious draw- back of substituting one set of offensive matters for anotlier. The younger Heberden, after describing these improve- ments, is guilty, I fear, of some exaggeration when he says that " in a few years the new town rose up like a phoenix from the Fire with increased vigour and beauty," producing in the country a spirit of improvement till then Wren^s Plan. 113 unknown. Allan Cunningham's picture of Sir Christopher Wren, harassed and disappointed, watching " in silence the new city rising up with streets confined and narrow, and house huddled upon house,mean,or plain, or neat, according to the pleasure or purse of the proprietor," is more in con- formity with the truth. The phcRuix which would have risen from the ashes of the Plague-smitten city, had Sir Christopher been allowed to mould it into shape, would have been a noble assemblage of streets from 90 feet wide down to a minimum of 30, bordered with houses uniform in plan. A spacious street would have stretched from Aid- gate to Temple Bar; a second, starting from the Tower,and meeting it at a sharp angle, enclosed St. Paul's Cathedral, with a piazza to the west. At the river's edge, a broad -quay extended from London Bridge to the Temple, with all the halls of the City Companies, alternating and contrastinor with merchants' warehouses, skirtino^ it throughout its whole length j while piazzas and markets dotted the scene, and the rebuilt city churches, at suitable distances, closed the vistas of houses, and •gave height and beauty to the whole. Add to this tantalizing vision of what might have been, an Exchange standing in the middle of a piazza (a sort of Roman forum with double porticoes), with bank, mint, post- office, excise office, and other public buildings grouped near it — a noble centre whence the streets should radiate to the principal parts of the city — and we have the heau ideal of a metropolis of a great nation, '' the wonder of the world." From this vision of beauty, the wholesome and the useful were not to be shut out. A canal was to be cut 120 feet wide with flushing arrangements at Holborn Bridge, and coal stores on either side 5 and churchyards, and trades requiring great fires, or yielding noisome smells, were to be placed beyond the limits of the city. This was no I ri4 Evelyn's Plan, architect's dream, for to use the words of Sir Christophers son, " the practicabihty of this whole scheme, without loss to any man, or infringement of any property, was at that time demonstrated, and all material objections fully weighed and answered." Perhaps it was a further recom- mendation of it that King Charles approved it and pre- sented it to the council. "The ingenious Mr. John Evelyn," too, propounded a plan, with a river-quay, straight wide streets, large open spaces with fountains and conduits, a Royal Exchange well placed on the river, and public buildings judiciously distributed — if I may offer an opinion on such a subject, a good, wholesome, handsome plan, though not equal to that of our great architect. But the citizens did not like either plan or any plan at all. They would not submit to the necessary delay j they had a preference for narrow streets, crooked lanes, and blind courts ; thought a crowded city in itself beautiful ; and did not want their new capital to " look like a city of lords rather than of merchants." And thus was lost this golden opportunity "of making the new city the most magnificent as well as commodious for health and trade of any upon earth." London, then, having risen from its ashes witli wider streets, less combustible and more spacious houses, and better sanitary arrangements 3 but with no grand and comprehensive structural improvements, and with its out- lyincr districts unchanged 5 let us try to find out what effect was produced upon the health of the inhabitants in the remaining third of the seventeentli century. As the Bills of Mortality, for the two years 1667 and 1668 give the returns of births and deaths only for the 16 parishes left standing, and not for the 97 parishes within the walls till 1669, it is safe to infer that the city began to be inhabited afresh in this year 1669. It further appears from the figures for subsequent years that the The Fire and the Plagiic. 115 work of re-population must have been a gradual one. The number of births shows a progressive increase for 1 2 years, and the deaths exhibit the same tendency, with marked fluctuations. Now, during all these years, from 1667 to 1679, when the last entry under the head of the Plague occurs, there are recorded no less than 82 deaths from plague, and not one of these took place within the limits of the re-built city, or of the 16 parishes left standing. If then our examination of the Bills of Mortality were restricted to the years following the Great Fire, we should naturally infer that the reconstructed city was proof against the plague that still continued to attack the inhabitants of the out-lying parishes which the fire had spared. But this inference would be unsound 3 for, on examining the Bills for the years 1657 to 1664 preceding the Plague and the Fire, I find that while no less than 113 deaths by plague occurred in the out-parishes, only 2 took place in those within the walls 3 and that in the five years 1 660 to 1 664, the returns for which include the five Westminster parishes, we have one death only within the walls for 60 without the walls. We are justified, therefore, in inferring that, except in years when Plague was epidemic, the city within the walls was very nearly plague-proof 3 and also in disturb- ing the behef generally entertained that the Great Fire gave the coup de grace to the Plague. This amended view of the subject receives some support from the fact that the proportion of deaths by plague to deaths from all other causes was always, even in epidemic years, lower in the 97 parishes within, than in those without, the city, or those described as out-parishes. Thus, in 1625, while 64 per cent, of the deaths within the city were set down to plague, and 64 also in the parishes without the walls, 70 per cent, was the ratio for the out- parishes. Again, in 1636, while the ratio of deaths from I 2 I T 6 What the Fire did not do. plague was only 30 per cent, within, it was 40 per cent, without, the walls, and 70 per cent, in the out-parishes. And again, in 1665, the deaths by plague within the walls having been 6^ per cent, of the total deaths^ they were 70 per cent, in both groups of out-lying parishes. Doubtless the city within the walls was always a superior place of residence. Its Cathedral, its Exchange, and its city companies claimed space for themselves, and its wealthy citizens lived in better houses and wider streets than the people in the out-lying parishes. It was in such labyrinths of narrow and squalid streets, as some of us remember in the **^ rookery" of St. Giles, before New Oxford Street was run through it, that the poverty and crime of London took up their abode 5 and in such dis- tricts the plague was rife in epidemic years, and lingered in the years when the parishes within the walls were free. So that it is not true that the Fire of London, so often spoken of as a blessing in disguise, brought about a state of things which guaranteed us against future epidemics of the Plague; for it left standing not only 16 parishes within, and 14 out of 16 without, the walls, but all the out-lying parishes in which the Plague had always proved most fatal and lingered longest. The peculiar hunting grounds of the pestilence remained intact, and probably underwent little change during the last years of the seven- teenth century. They were far from plague-proof 5 and we must look elsewhere than to the Fire, which did not touch them, for the causes of the immunity from the Plague which, as we know, many cities of the continent did not enjoy. If the Great Fire did give us wider streets, better houses and improved municipal arrangements, it was at the cost of the destruction of many noble buildings we could ill spare, and of more than one library we could not replace. " This blessing in disguise," like the "phoenix" Health of London in the I'jth Century. 117 which Heberden imagined, must, I fear, be added to the delusions which a pious fancy has framed but a just criticism dispels. What the Fire and the Plague did was to disturb and dislocate the population of London, thus placing a serious obstacle in the way of all comparisons of the numbers and causes of death in the years following. And the same obstacle, though in a minor degree, was created by the plague epidemics of 1603, 1625, and 1636. If, in addition to this disturbing cause, we take into account the unsatis- factory way in which the returns of the causes of death were made, the exclusion of deaths of Jews and Quakers, the changes in the nomenclature, the difficulty of ascer- taining the meaning of terms, the acknowledged defects in the returns of births, the additions so often made of new parishes to those comprised in the returns, and, above all, the want of trustworthy censuses of population, we shall see the necessity of proceeding with great caution in any attempt to ascertain the sanitary condition of the inhabitants of London at different periods of the seventeenth century. The only data which may, I think, be used without much fear of misleading us, are the proportions which certain well defined and easily ascertained causes of death bear to the whole number of deaths, with the proviso that, in making choice of years, or groups of years, to be com- pared with each other, we avoid those in which the Plague was epidemic, and those also in which changes were made in the parishes comprised in the bills. Observing these precautions, I am able to select for comparison three periods of five years each, those ending 1635, those ending 1664, and those ending 1693. ^^ happens that these dates are separated by intervals of 29 years. Now I begin by arranging the causes of death in four groups: — i. Deaths in infancy and childhood j 2. Deaths in old age, and from diseases incident to the ii8 Diseases of the ijih Century. aged 3 3. Deaths by zymotic maladies, and 4. deaths by- consumption: and I find that the ratio of deaths in infancy and childhood to deaths from all causes was 37 per cent, in the five years ending 1635 '■> ^5 P^'" cent, in those ending 1664; and 32 per cent, in those ending 1693. Taking next the deaths in old age, I find that they were for the three periods respectively 8, 8, and 7 per cent. Next come the group of zymotic diseases j and I find that these gave rise to 23 per cent, of the deaths in the first five years, 28 per cent, in the second, and 32 per cent, in the third ; and lastly, consumption proved fatal to life in the ratios of 20, 21, and 17 per cent. You see then that the mortality of infants and children, which fell considerably towards the middle of the century, rose again, though not to the high level of the early years 5 that the number who reached old age was less at the end than at the beginning and middle of tlie century j that the deaths from zymotic maladies progressively increased throughout the whole period under review j and that this increase coincided with a marked fall in the deaths from consumption towards the end of the century. Let us now see what additional light is thrown on the sanitary state of the last part of the seventeenth century by the figures taken somewhat in detail. First, let us take the group of fevers — ague and fever, spotted fever, and plague. Well ! these gave rise to 14 per cent, in the five years ending 1635, ^"^ ^^ P^^ cent, in those ending 1664, and 1693 respectively: that is to say, 14, 16, and 16 per cent, of all causes of death put together. Let us take next in order small-pox and measles. The ratios for these two diseases are 5, 5, and 5^ per cent, for the three periods. Next let us take the several entries which comprise the deaths from dysentery, diarrhoea, and cholera. These Sydenhavis Observations. 119 increased in the remarkable ratios of 4, 7 J, and 16 per cent. The entries under scurvy and sores and ulcers, which we shall by-and-by find to be closely associated with dysentery in unwholesome ships, destroyed life in the ratios of 3, 8, and 5 per thousand. Syphilis increased at the rate of i, 3, and 4 per thousand. King's evil remained stationary at 3 per thousand ; while this and other diseases implying slow deaths in childhood, taken together, account for i per cent, of the deaths in the first period, 3 in the second, and 2 in the third. In these numerical statements, I take no account ot the estimated population at the three periods referred to j but only of the proportion of deaths from special causes to total deaths; and partly for this reason, that the limits of the Bills of Mortality were extended by succes- sive additions, seven parishes having been added between 1636 and 1664, and four between 1664 and 1693. I will finish what I have to say on the sanitary state of London in the last 30 years or so of the seventeenth century by stating my impression that there was an / increased mortality from fevers, from small-pox and I measles, from dysentery and bowel complaints, and from syphilis 3 that scrofula remained stationary ; that the ; diseases of children, at their worst about the middle of the , century, improved towards the end of it ; that the same is true of scorbutic maladies ; but that, on the whole, the health of London experienced no change for the better during the seventeenth century, except in the ^relief obtained from the incursions of the Plague. This inference from the Bills of Mortality is confirmed by a perusal of Sydenham's " Medical Observations con- cerning the History and Cure of Acute Diseases," sup- 1 20 Small'pox and Measles. plemented by his "Epistles," which works contain an account of the epidemic diseases of London, extending, over the 25 years from 1661 to 1685. I will briefly state what I glean from these works. In the first place, I learn that autumnal intermittents,. severe and very fatal, which had been on the increase for some years previous to 1661, broke out about the begin- ning of July of that year, and by August " were doing fearful mischief," causing excessive mortality, and carry- ing off whole families, and that these agues continued to prevail till 1665, ^^ 7^^^ °* ^^^^ Plague. After that they became of " exceeding rarity " till the year 1678. This statement agrees well with the entries in. the London Bills, which indicate 1661 to 1665, and also 1685-86, as well marked epidemic years for ague and fever. Continued fever prevailed in many different forms j at one time (as from 1661 to 1665) a miniature of the inter- mittent j at another (as in 1667) a sort of small-pox. without a rash 5 at another (as in 1 669) a kind of dysen- teric fever 3 at another (as in 1685) complicated with cough : always, as Sydenham thought, modelled some- what after the fashion of the prev^ailing epidemic, what- ever that might be, whether ague, small-pox, or dysentery. In 1685-86 this continued fever, complicated with cough, was epidemic not in London only, but in all England^ There was a like epidemic in 1679 j and if we retrace our steps to the great plague year 1665, we find the long, cold, dry winter very productive of bronchitis, pleurisy^, and quinsey. Small-pox, in some years " favourable and of regular type," in others "anomalous," "black," "irregular," was epidemic about once in three years, and measles, of extreme severity in 1674, and less fatal in 1664 and 1670., Syphilis. 121 about once in two years. Measles more than once proved, the epidemic forerunner of the small-pox. Dysentery, very severe and fatal in 1669, was seen in form of epidemic every three or four years ; and the cholera morbus of Sydenham (the English cholera of our own day in an aggravated form) sometimes, as in 1669;, associated with coHc and dysentery, paid our London ancestors a visit of five or six weeks in the months of August and September of more than one of the years- under review. The disease we now call bronchitis, with pleurisy and quinsey, were epidemic in the seventeenth century as they are now, whenever a long, cold, dry winter occurred to test the vital powders of the aged, the weak, and the intemperate: 1665 and 1683 were such winters, and had such consequences. It was in 1683 that, as Sydenham states, " the cold was more severe than it had ever been within the memory of man. So cold was it that the noble river Thames was frozen up, so that carriages could pass upon it, and shops be opened, and business done just as in a street," the people *' walking on the solid ice as on a pavement." The next year was not "much below it," but the cold did not last so long. There is one disease described by Sydenham which I have not yet noticed j the lues venerea. I find it credited in the Bills with a number of deaths increasing towards the end of the century. In 1675 ^^ caused 97 deaths, in 1680, 1 14 J in J 694, 104. What a terrible scourge it was may be inferred from Sydenham's description of it. After enumerating its ravages among the several textures and organs of the body — ravages which w^e, in these days,, witness rarely in the worst cases — he describes the un- happy patient as wasting away in " continual torture," dragging on an existence which " pain, foetor, caries, and shame," make w^orse than any death, till *^ at length. 7 22 yohn Woodall and the Scurvy. limb by limb perishing away, the lacerated body, a burden to earth, finds ease only in the grave." Sydenham has no difficulty in fixing on 1493 as the date of the introduc- tion of this scourge into Europe, and on the coast of Guinea as its birth-place. If so, it may be added to the long list of injuries which the slave trade inflicted upon us. This brief reference to the works of our great physician has certainly confirmed the teachings of the Bills of Mor- tality ; and assuredly the w^ords with which he concludes his chapter on the Quinsey do not exaggerate the work the physicians of the last half of the seventeenth century had to do. " A murderous array of diseases " had " to be fought against, and the battle " was ^' not a battle for the slug- gard. Day by day there" was "a combat against the life of man, and there " "was neither truce nor quarter. Many " died " by violent deaths 3 but, with tlie exception of these, two-thirds of our race " died *^ of fevers," making ''^ continuous attacks," and winning "daily victories over strong men in the flower of their age." And yet these destructive epidemics, some of which, like plague, are wholly, and some, like ague, nearly extinct, as causes of death j and others, as syphilis, hav^e lost much of their malignity j prevailed in a century by no means wanting in great physiological and medical dis- coveries, or destitute of new and valuable sanitary appli- ances. Early in the second quarter (1628) Harvey made his grand discovery, or rather complete demonstration, of the circulation of the blood. The lacteals had been discovered six years before j and, as early as 161 7, John Woodall, surgeon to St. Bartholomew's, and inventor of the Trephine, in his " Surgeon's Mate, or Military and Domestic Medicine," recommended lemon-juice in scuny, not daring to give it its due praise as a sauce to meat, " lest the chief in the ship should waste it in the great cabin to save vinegar." The Cool Regimen. 1 23 The middle of the century witnessed the introduction and sale in London of more than one article of diet, and of one medicine, that must have had some effect on the health of the people. Coffee, chocolate, and tea, were first sold as drinks between the years 1655 ^"^ ^^57» and the Peruvian Bark, a specific for the ague, was sold in I 658, having been introduced in 1 6^^, and firmly estab- lished as a medicine of repute by 1663. Sydenham made free use of it in a regular way, and one Talbor as a secret remedy. Need 1 remind you that tobacco was in common use throughout the whole of the seventeenth century ? that it had the honour of being attacked by James 1., and legally persecuted in 1 604 ? that despotic emperors, infal- lible popes, and intolerant Swiss republics, brought all their artiller)- of punishment to bear on those who used it as snuff, or smoked it 3 and that the irrepressible weed, ** loathsome to the eye, hatefull to the nose, harmefuU to the brain, dangerous to the lungs," still sends up its "blacke stinking fume " — ** its horrible Stygian smoake" — in burning deserts, and wintry solitudes, the seaman's luxury, the prisoner's temptation, the pet weakness of civilized, and the prime enjoyment of savage, men. So that, in the "^ daily combat against the life of man," Sydenham was armed with Cinchona Bark, in addition to the old and well tried-remedies — mercury, antimony, opium, and the lancet, all of which he used freely, but with discre- tion. But he armed himself also with something better than these, and especially important in its bearing on the diseases which were the chief objects of his study. He revived, and stamped with the weight of his great authority, the use of that '' cool regimen," of which the value is said to have been first recognised and proved by John Crane, who practised in Cambridge, and died there in 1552. If we must affix a date to Sydenham's revival of this method, 1683 will be the year. 1 24 Fatal Diseases But what with want of appreciation (the case of lemon- juice) 3 or scarcity, clearness, and adulteration, backed by apparent failure, or worse, in some conspicuous case (as happened with the bark) j or obstinate prejudice (such as the cool regimen had to contend with) 5 or the chronic resistance of old habits (as in the contest of coffee, choco- late, and tea, with beer, spirits, and wine) : the practical effect of these drinks and medicines, like the reforms in medical treatment, and the improvements in the houses, clothing, dietaries, and habits of the people, was not con- siderable J and we arrive at the end of the seventeenth century with anything but a clean bill of health. And now I must devote what remains of this Lecture to the prevalent and fatal diseases of the eighteenth century, using for this purpose chiefly the facts relating to the metropolis, and dividing the century, as I said I should do, into two equal halves. I might, indeed, have adopted with great propriety an unequal division at the year 1 774, inasmuch as up to that date the history of the century is marked rather by steady progress towards a better state of things than by any grand sanitary event ; while the year 1774, as you must have inferred from -what I said in my lirst Lecture, is a date never to be forgotten by Englishmen so long as they hold in esteem the greatest virtues displayed in the purchase of the greatest blessings. But if I had adopted this division I must have separated the great sani- tary reforms of Sir George Baker and Captain Cook from the still greater ones which we owe to John Howard and Edward Jenner. By dividing the century into two equal halves, I shall be able to bring together, as the work of the last years of the second half, the sanitary labours and reforms of these four men. I shall begin my inquiry into the sanitary state of the eighteenth centur}- by comparing the ratios borne by the four leading groups and causes of death — infants and children j Of the Eighteenth Century. 1 25 aged, zymotic diseases, and consumption — with deaths from all causes, for each of the years 1700, 1725, 1750, 1775, and 1 800 J and to give more value to these figures, I shall compare them with the years 1650 and iSjo. I take first in order the deaths of infants and young children, and I find the ratios to be as follows : — 1 700, '^,6 j 1725075 1750^35 1775^ 345 1800,26. The deaths in old age, and from the chief diseases inci- dent to age, run thus : — i 700, 7 ; i 725, 9 3 i 750, also 9 j 1775, 8) 1800, 9. Zymotic diseases, which I take next, occasioned the following proportionate numbers of deaths: — 1700,30; 1725,29; 1750,25; 1775, also 25; 1800,21. And lastly, consumption contributed the quota of deaths shown in these figures: — 1700, 15 ; 1725, also 15; 1750, 21; 1775, 26 ; 1800, 29. If I read these figures aright, they justify these infe- rences : — That the deaths of infants and young children were less numerous in proportion at the end of the century than at the beginning ; and those in old age somewhat more numerous ; that the deaths by zymotic maladies fell continuously from 30 to 21 ; while those attributed to consumption increased, also continuously, from 15 to 29. If we compare the first with the last year of the century, we find a decrease in the mortality of infants and children of more than one fourth ; an increase in that of old persons of less than one-third; a decrease in that by zymotic maladies of one-third ; an increase in the deaths by con- sumption of nearly 50 per cent. Let us now take the figures for the years 1650, i 750, and 1850, and see what they teach us. For infants and young children, they are 32, -^o^, and 13 percent.; for aged persons, 9, 9, and 13; for zymotic maladies, 18, 25, and 2 1; and for consumption, 23, 21, and 14. I infer from these figures that the middle of the eighteenth cen- 126 First Quarter of the Centuiy. tury was, on the whole, less favourable to life, and more in- fested by zymotic maladies than the middle of the seven- teenth, and that the middle of the nineteenth century showed a marked improvement over both its predecessors, except in the item of zymotic maladies, in which the middle of the seventeenth century contrasts very favourably with it. These figures, which relate to single years, are, of course^ somewhat modified if we substitute periods of five years each. I have made calculations on this basis, and find that the results are in harmony with those for single years j but they give us a less favourable impression of the first 25 years of the century, and even of the last 25, while the numbers for the second and third quarters justify the view that those were periods of progressive sanitar}'- improve- ment. At any rate, the figures for the years ending 1725 stimulate the curiosity to look somewhat closely at the facts at our disposal relating to this, the first quarter of the century. Beginning with the Bills of Mortality, and passing the more fatal maladies in review, I find that there are abrupt transitions in the figures which I do not find in our own times. Thus, to take but one example, there were 12 deaths from measles in 1704, 319 the year following, and 361 the year after that. Other figures, which I have before me, display frequent fluctuations eminently charac- teristic of epidemic maladies. Of the 25 years, 11 are remarkable for excess of mortality, and for the number of diseases that contribute to it. The inference drawn from the London Bills is amply con- firmed by the facts contained in Dr. Thomas Short's care- ful and learned compilation, in which the weather and diseases in England and on the Continent are recorded year by year. The most notable fact bearing indirectly on our own sanitary history is the prevalence of the Plague among the northern nations of the Continent, from 1702 Second Qicarter of the Century. 127 to 17163 and it is worthy of remark that a ''malignant fever," "very mortal," raged 'Mn Harwich, Sec," in 1709, "from the communication with foreign parts." In 1710, again, we read of " a catarrhous fever, called the Dunkirk rant, or Dunkirk ague," '' brought by disbanded soldiers into England 3" also of the small-pox and spotted fever, very fatal in Norwich. The two years, i 714 and 1723, are noticed as peculiarly fatal throughout England. This last year (1723), as well as 1710, the influenza was epi- demic j and in 1724 the colic was so general in Devon- shire, as to be called an epidemic. Time will not allow me to dwell on the severe winters, storms, droughts, scarcities, atmospheric disturbances, and epizootics of this period. But I may remark that the yearly details remind one of the earlier times when our worst pestilences prevailed. Of sanitary inventions and improvements belonging to this first quarter of the eighteenth century, I have also little to say. The most interesting procedure of the kind was the oractice of inoculation, introduced into Ensrland in 1722, of which the history belongs to the last Lecture of this course. Another sanitary procedure belonging to this first half of the century relates to ventilation, of which more presently. In treating of the prevalent and fatal diseases of the second quarter of the century, I am still able to avail myself of the London Bills, and of the valuable compila- tion of Dr. Short. I find that the annual fluctuations in the deaths are still very large. I will give a few examples : — Ague, which occasioned 11 deaths in 1727, caused 44 in 17285 fevers which destroyed 4003 in 1740, killed 7528 the year following 3 small-pox, set down for 1206 deaths in I 745, figures for 3236 in 17463 and measles, which destroyed 30 in 1732, proved fatal to no less that 605 in 1733. Quinsey shows a fluctuation from 10 to 31, ery- 128 The hiflnenza of i73:z-3. sipelas from i to 5, dysentery from 2 to 15, and English cholera from 22 to 103 in successive years. The largest increase in the aggregate mortality occurred in 1 733. The previous year the deaths exceeded 23,000 : that year they were upwards of 29,000. The years marked by a high mortality were, as in the lirst quarter, 1 1 in number, or little less than one-half. I now turn to Dr. Short's pages again, to see how far his statements, based, as they are, partly on his own ex- perience, partly on the facts carefully recorded by Win- tringham, Huxham, Hillary, and others, bear out these inferences from the London Bills. From the two together we learn that while the last two years of the first quarter of the century were healthy, the second quarter began with a decided increase of mortality, small-pox being the only one of its class that did not prove unusually fatal. The next was a year of scarcity. Dys- entery prevailed, fever continued common, and small-pox took the place of measles. Passing over the more healthy year, 1728, we come to 1729, a year marked by a high mortality from all the epidemics, except measles, and in September by an attack of influenza. The season was unusually "moist, rainy, cloudy, and foggy," and " of a sudden," there " broke out and raged all over Europe, and perhaps the globe, a most universal epidemic catarrh." *' In London near 1000 died weekly during September." Of the frightful mortahty of the small-pox this year we may form some idea from the fact tliat at Ipswich 13 out of 19 died. 1729, then, was doubtless a very fatal year j and Short says of it, and of some years preceding, " that the insalubrity of the air was universal." The years i 730 and I 73 I were healthy years 3 but the winter of 1732-3 wit- nessed another outbreak of influenza, which Dr. Short characterizes as " the most sudden and universally epidemic catarrh that has been in this age, sparing neither ranks. Ma lignan i Spotted Feve7' 0/1^4.1. 129 sexes, ages j" "old or young, weak or strongs" and killing off " many hectic and phthisical people." It was a particular attention to this epidemic, and its consequences, that first set Short upon that " quest of epidemics in all agesj" which, as he says, gave him a better acquaintance with physic than all " his former studies 3 and convinced" him, not only of ** the uselessness, but perniciousness, of theories and hypotheses in practice." That part of the epidemic influenza of 1732-3 which belonged to 1732 did not tell upon the mortality so as to prevent it from being what Huxham calls it, " the most favourable and kindly season for health that had been above sixty years before." But things were so changed in the early part of 1733, that the deaths which in the first week in February (in London) were 1156, increased to a maximum of 1588, of which ''never happened the like before, since the great Plague." There were two other outbreaks of influenza in this second quarter of the century -, one, described by Huxham, in 1 737, and another, also described by him, in 1743. So that we have in this space of twenty-five years, four well-marked epidemics of influenza 5 in the years 1729, 1733, 1737, and 1743. Between 1733 and 1736 two comparatively healthy years were interposed -, and then we come upon two years of higher mortality, in which measles, and small-pox, and quinseys are rife, with much mortality among cattle. Measles were especially fatal. In 1737 influenza pre- vailed. Then, we have two comparatively healthy years, followed by a year of scarcity (i 740) caused by a long, severe winter leading up to a late summer, " a most memorable year in future histories." In 1741, '*a malig- nant spotted fever raged among the poor, who had been half-starved the last two years," — a fever much the same as that which raged in Bristol the year before and in Galvvay this same year, but modified since its importation K 130 Early History of Ventilation. by two men of war from Gibraltar into Plymouth in 1 740 — a fever so bad that it would probably have been " a true plague, had the constitution of the air favoured it" — ''the most general, frightful, and fatal" that Dr. Short "had ever seen." From 1742 to 1745, the death-rate in London was, on the whole, favourable; but there was an exception in the case of children J for, in the year 1742, there was a renewal of that " putrid sore throat," that viorlus strangu- latorius, which had been seen in Spain in 1610, and first recognised in England in 1 739, and with which the name of Fothergill is so honourably associated. It seems to have been common in London and near it in 1746, and attained its acme in 1 747-48. It was the scarlet fever of our own day, in its very worst form, eminently contagious, and so fatal that it " carried off whole famihes of children, and seized some of their attendants," and "in one small market-town" 80 out of 90, treated by bleeding, died. The years 1 746 and i 747, but especially the first of these, were years of high mortality. Small-pox, spotted fever, dysenter)% and measles all prevailed, and the death-rate was very high. The last three years of the second quarter of the century, were healthy, but measles were very fatal in the first, and dysentery in the last of the triad. The sanitary reforms and improvements most deserving of attention in this first half of the century are : i. The progress of Inoculation j 2, The successful attempts made to ventilate our ships and buildings, and 3. The eminently disastrous, and, because disastrous, instructive expedition of Anson in i 740. Of these the subject of Ventilation alone requires to be noticed in this place. The practice of Inoculation will be examined in my eighth Lecture, and Anson's voyage in my next. The early history of ventilation is extremely interesting. Wren and Desaguliers. 131 It may be said to date from a time when the legislature first felt the want of air in the House of Commons, and called the great architect Sir Christopher Wren to remedy the defect. This he did by making a square hole in the ceiling of the House at each corner, which hole formed the base of a truncated pyramid rising six or eight feet into the room above. Sir Christopher, of course, expected that the air from the House would always rise through these short chimneys, forgetting that air in chimneys is greatly assisted in its upward movement by the tire, and has an awkward habit of passing the other way when there is no fire burning. This was found to happen whenever the air in the room above was colder than that of the house itself. Those members who happened to be near the corners found themselves in the same shower-bath of cold air that I once felt when sitting in the old reading- room of the British Museum under a hole in the ceiling covered by an ornamental patera. At what time Sir Christopher was employed to do this work, I do not know J but it was in 1723 that Desaguliers was asked to remedy the inconvenience. This he did very effectually by closing the four pyramids at the top, and carrying tubes from openings in their sides to fire-places in two closets, so that the air of the House should feed the fires and pass away through the chimneys. The fires were to be lighted before the members met, and when this was done the plan answered completely, and the House was kept very cool. But Desaguliers and his plan had an unexpected difficulty to encounter, Mrs. Smith, the housekeeper, was disturbed in the possession of her rooms, and with skill equal to his own, baffled his designs, and daily stifled the House without incurring its displeasure. Her plan of operation was simple and efl^ectual. Instead of lighting the fires before the House met, she waited till the House was heated. Sir George Beaumont and K 2 132 Mi\ Sainnel S^Uton. others " observing that the design of cooling the House was frustrated," but not, I presume, suspecting the wicked housekeeper, applied to the doctor for some contrivance for extracting the hot air which should be under his own control. This was in 1736. The doctor again proved himself equal to the occasion by inventing " a centrifugal or blowing wheel," which was *^ able to suck out the foul air or throw in fresh, or to do botli at once," as the Speaker might be pleased to command. But, important as it was to promote the comfort and health of the nation's representatives, there was a class of men who stood much more in need of assistance, and were, in their way, quite as valuable to the nation — I mean our soldiers and sailors. About this time an expedition was being organized against the Spaniards. The troops- had been embarked at Spithead, but numbers of them were obliged to be relanded and sent to hospital j for the ships "stunk to such a degree that they infected one another." The Lords of the Admiralty accordingly ap- plied to Desaguliers, saw his models at work, and, in company with Sir Jacob Ackworth, the surveyor of the Navy, inspected the wheel fixed over the House of Commons. The authorities were satisfied, and ordered a smaller wheel to be tried on board the Kinsale^ at Woolwich. This was done 3 but Sir Jacob contrived to bring the machine into disrepute by a rough and off-hand comparison with the old wind-sail, and dismissed the whole affair, expressing regret at the failure of the doctor's wheel, and saying that " he thought it might be a very pretty thing in a house." Sir Jacob was then dealing with a philosopher, and easily contrived to give what was called the " shuffling kick " to the machine and its contriver. But he was soon to encounter a sturdier antagonist in a worthy brewer, Mj. Samuel Sutton, who, touched with compas- His Ventilation of Ships. 133 sion for the poor sufferers at Spithead, determined to try "what could be done by fire." He accordingly made a preliminary experiment in a room with three fire-places, and found that, on kindling large fires in two of them, the air that came down the third chimney was able to put out a candle, and that when all the fires were lighted, the air entered the room with such force, *' as to raise a pulley with half a hundred weight." This use of fire to produce a draft was the essence of Desaguliers' first plan for ventilating the House of Commons j but Sutton probably did not know this. Be this as it may, he gave himself very earnestly to the work of ventilating ships on this principle. He made use of the fire or fires already existing on board the ship, and led a pipe from the ship's well, or from any other part of the vessel where change of air was needed, to the ash-pit, and so caused the foul air to blow the fire, and pass away up the •chimney. What steps the sturdy brewer took to com- mend his cheap and simple invention 5 how some prac- tical sailors pitied him, as being mad 3 how Sir Charles Wager gave him a letter of introduction to the redoubt- able Sir Jacob ; how he told him " that no experiment should be made if he could hinder it 3" how he petitioned the Lords of the Admiralty j how they gave orders that were set at nought ; how he commended himself to Dr. Mead, and Martin Folkes, President of the Royal Society j how these gentlemen waited on the Lords of the Admiralty, who again ordered the plan to be tried 3 how it was tried in presence of Mead and Folkes, and several other members, and Sir Jacob Ackworth, who was sorry to see them come " to the trial of such a foolish experi- ment 3" how the experiment answered to the satisfaction of all present 3 how Sir Charles Wager gave a peremp- tory order which was at last carried out on board the Norwich man-of-war 3 how Sutton received from the 3 34 Sutton and the Admiralty. Admiralty the magnificent reward of loo/. j and how, after troubles, trials, and disappointments innumerable, he had, at last, the satisfaction of seeing his pipes fixed on board all his Majesty's ships, I have not time to tell you. Nor can I stop to describe Dr. Hales' invention of a species of bellows, his 'Ship's lungs," which had the dis- advantage, in common with Desaguliers' wheel, of not being self-acting. This history must finish for the present with a brief statement that, in spite of the proved efficacy of Sutton's simple and cheap plan, and its power of saving lives so valuable, he was employed only for a brief space in fixing his apparatus in king's ships and Indiamen, and that in a year or two no other method of ventilation was known on board ship but the " old way of wind-sails," which egregiously failed when most wanted, namely in calms and in rough weather. How useless the wind-sail ventilator was in bad weather, Anson's little fleet lying at Spithead when the experiments of Hales and Sutton were in progress, and which left England without any other provision for ventilation, was destined soon to discover by a most bitter experience. Sutton successfully applied his plan to buildings, and wished to extend it to Newgate 3 but though he expected to find an unanswerable argument in his favour in the outbreak of jail fever that took place in the last year of the half century (1750), he was disappointed, and the prison was allowed to remain as before. I have introduced this subject of ventilation, as belong- ing to the history of sanitary science in the second quarter, or first half, of tlie century, and as a contributory to the improved health of which there are indications. It is true that Desaguliers, Sutton, and Hales were all doomed to disappointment, and that their plans fell into disuse 3 but publicity was secured, and ventilators and schemes of ventilation came into fashion 3 so that, when Third Quarter of the \^th Century. 135 the managers of public establishments found their build- ings offensive, and deemed them dangerous, there was always some ingenious person to assist them in the work of improvement. Hence it happened that, in 1784, St. Thomas's Hospital was ventilated by a Mr. White- hurst, of Derby 3 that the year following a contrivance, borrowed from a French frigate, began to be used in English vessels of war 3 and that here and there ventila- tion was brought to bear on the jail fever. In what remains of this Lecture, I must treat briefly of the sanitary state of the last half of the eighteenth cen- tury, dividing it for convenience into quarters. And here, as I lose Dr. Short's guidance, and Dr. Fothergill's annual reports of the seasons and sickness only extend to a few years of the third quarter, I will limit myself chiefly to what I can glean from the Bills of Mortality. Beginning with the third quarter, I must remind you that the figures already adduced indicate a marked im- provement over the quarter preceding in zymotic, or epidemic maladies. They fell in the ratio of 26 to 20, the mortality of children being stationary, while that of aged persons fell in the ratio of 9 to 8, and deaths from consumption maintained their progressive increase. On the whole, too, the figures show less violent fluctuations from year to year, with the exception of diarrhoea, small-pox, and measles, and which continue very fatal and very fluctuating. Thus small-pox, which killed 38 per- sons in 1766, destroyed 11 96 the year following, and 1987 the year after that j and measles credited with 79^^ deaths in 1774, caused 15 the year previous, and only I death the year following. The influenza prevailed as an epidemic four times in this third quarter: — in 1758, 1762, 1767, and 1775: and it occurred, as you recollect, four times in the second quarter. 13*5 Last Qiuirter of the \%th Centiu^y. The last quarter of the century, which displays a maiked decrease in the mortality of children, and some increase in that of aged persons, shows a reaction, to the amount of one-tenth, in zymotic maladies, and a great increase in deatlis from consumption j and we do not find any case of such extreme annual fluctuation in small-pox and measles as occurred in the previous quarter. The greatest fluctuation in small-pox occurs in the years 1770-72. The deaths were 871 in the first year, 3500 in the second, and 636 in the third. Measles shows its greatest fluctuation in 1 785-86. In the first year it caused 20 deaths, in the second 793. Next year the deaths fell to 84. Dysentery and diarrhoea show a remarkable increase in 1780 and 1781 5 the entry of *' ague " and "ague and fever" give place during the last ten years of the century to the simple entry " fever," and influenza seems to have attracted attention once only in this quarter, in 1782. Of the quarter generally it may be said that it shows some improvement over its predecessor. But the year 1800 was marked by an increase in infantile mortality, in small- pox and measles, and in the death-rate from all causes. To what I have said of the prevalent and fatal diseases of the eighteenth century, I will only add that the London Bills for the first quarter of the nineteenth exhibit at a glance a very material improvement in the public health. The figures in the column headed " fever " show a marked railing ofFj small-pox is evidently on the decrease, and the total mortality exhibits both diminished intensity and greater freedom from fluctuation. The great sanitary reforms of the last half of the century had evidently left their mark on the death-registers of the early part of the nineteenth century. They are almost summed up in the words, lead colic, scurvy, jail-fever, small-pox : in the honoured names of Baker, Cook, Howard, and Jenner. ^2>7 LECTURE VI. THE SCURVY. I AM now to treat of lead colic and scurvy ; of the first, briefly, of the second more at large. Briefly of the first, because I have already, in my first Lecture, spoken of Sir George Baker's discovery of lead impregnation as the true cause of the colic that seized the drinkers of Dev^onshire cyder. I now revert to the subject as belonging to the sanitary reforms of the eighteenth century, and of the third quarter of it. The date of the discovery is 1767. It is, therefore, the first of that remarkable series of sanitary improvements and reforms which ended with the triumph of vaccination in 1 796. In my first Lecture I proved by figures the wide preva- lence of lead poisoning in Devonshire. I will now adduce further proofs of the same sort from the treatise of Hux- ham, who practised at Plymouth, and is in every way a good authority. He tells us that, early ir. the autumn of 1724, "a disorder exceedingly epidemical spread itself over all the county of Devon, among the populace espe- cially." It lasted till the following spring. It was so '' vastly common " that there was " scarce a family amongst the lower rank of people that had it not," and he often saw five or six lying ill of it in the same house. Such an epidemic colic was never seen before, unless it were that described by Paulus iEgineta as attacking many parts of Italy and the Roman empire, and which was un- doubtedly the lead colic, attended by palsy and epilepsy, a 138 The Devonshire Colic. was this of Devonshire. Huxham traced it to an incredible quantity of apples. No such apple-year had occurred within the memory of man, and the quantity of cyder was in proportion. Huxham recognised the coincidence of much colic and many apples j but he (and Musgrave before him) missed the true cause which Sir George Baker so happily discovered. This same coincidence had struck Huxham in the years 1722, 1728, 1730, and 17355 but in none of these was the disease so prevalent, or the apple- harvest so abundant. Under the year 1735, and the month of January, Short has this brief entry : " A colic with severe rheumatic pains, and sometimes with a palsy of the arms and hands." Sydenham, too, speaking of the Colica Pictonum, says, " this is a sort of colic, which is wont to degenerate into palsy," and *' is extremely common in the West Indies, where it destroys many persons." To what extent this lead-colic prevailed in other parts of England to which the cyder was sent, we do not know j but it was certainly largely consumed by " scorbutical sailors," of whom Huxham saw a great many cured by apples and cyder alone, and knew the cyder to prove very salutary to sailors voyaging to the East or West Indies. In his short essay on " A Method for preserving the Health of Seamen in long Cruises and Voyages," he prescribed at least a pint a day of " sound, generous cyder " for every sailor. This advice from so eminent a physician, practising in a great seaport in Devonshire, must, I fear, have often caused the colic while it cured the scurvy. I have said enough to show that Sir George Baker would have rendered excellent service if his discovery had benefited only the people of his own county, and the sailors resorting to its ports. But when we reflect how often lead found its way, intentionally or by accident, into other liquids in common use — into drinking water, wine, and spirits — and in how many other ways it gains access Reqiurements of the i^lk Centitry. 139 to the system, we can scarcely appreciate too highly the services of the scientific physician, who, while riveting the attention for a time on one notable form of lead poisoning, warns us of the clanger we incur from it in so many other ways. It is a great feat to have detected and disarmed so subtle a foe to health and life — the cause of pain, palsy,, epilepsy, and coma. I may here mention the fact that, in i 755, a few years before Baker wrote about the lead coHc, an anonymous writer called the attention of the public to the danger arising from the extensive use then made of copper and brass vessels in washing, brewing, cooking, and preserving, as well as the bad custom of *' the good housewife," who would use copper to colour her pickles. Before I proceed to speak of the scurvy, let me remind you of the peculiar character and exigencies of the eighteenth century, of the prevalent and fatal diseases of which I am treating. It was, emphatically, a century of war- like struggles by land and sea, of national aggrandizement, of wonderful energy and activity directed outwards. We had, it is true, rebellions in England, Scotland, and Ireland j but our great work lay beyond our own limits. We had to fight with France, Spain, Holland, and America j and to es- tablish and maintain an empire in India 3 and as the seven- teenth century left us a legacy of war, the nineteenth saw us in the midst of one of the greatest struggles that history records. Taking the whole century into account, war was the rule, peace the rare and short exception. Battles and sieges, captured countries and islands, strong military posi- tions taken and held, hostile fleets encountered and defeated, disasters suffered and retrieved, crowd the canvas. We lost our great American colony, and won an Indian empire. For these gigantic struggles two things at least were needed — money and men. Money we might get in part by borrowing, and of that resource we largely availed 140 The Scurvy . ourselves j but men must be forthcoming as they were needed, and they must be mainly the growth of our own soil. Now our English population, at the beginning of the century, little exceeded six miUion souls, and a liberal estimate for Scotland and Ireland would raise it to nine j and out of this nine miUion, and its increase from year to year, the men necessary to supply the cruel waste of war by land and sea had to be taken. And yet, at the end of the centur}', we were richer in men than at the beginning of it. The six millions had grown to nine, and the inexo- rable demands of war had been supplied. If I am asked how this came to pass, I answer in three ways — by tlie simple growth of population, by savings effected in the lives of infants and young children, and by like savings among our adult population, but especially soldiers and sailors. Of the second I spoke in my last Lecture 3 of the third I shall have much to say in what remains of the course : of scurvy and the jail- distemper, in reference to the wars of the eighteenth century, and of small-pox as bear- ing on the early struggles of the nineteenth. Of the many maladies known to medical men, scurvy is the one respecting which oar knowledge is most com- plete and satisfactory. We recognise it with ease ; wc understand its nature, we are in no doubt as to its cause ■. we have full knowledge of the diseases with which it associates 3 we know by what atmospheric and other con- ditions it may be promoted, and we have learnt both how to prevent it and how to cure it. We recognise it by the mulberry coloured spots, or blotches, on the extremities, on the trunk, on any and every part of the surface of the body 3 by the dark, swollen, and spongy gums 3 by the bleeding condition of the whole frame ; not of one part, but of all. Its nature, or essential character, then, is the escape of blood from the vessels which in health hold and contain it. Its o.ssociaie diseases are foul ulcers, dysenteries. The Potato. 141 and fevers. The conditions wliich promote it are cold and damp, insufficient clothing, foul air, tainted water, over fatigue and exposure, mental listlessness and depression. Its true cause is a diet from which vegetables and fruits have been excluded. Its prevention and its cure alike consist in their supply or restoration. All this was known long ago 3 and I have already stated that, as early as 1617, Woodall extolled the virtues of lemon-juice. But in recent times we have been able to give to our know- ledge both of cause and cure greater precision. We have had experience of paupers and prisoners whose dietary contained but one vegetable element — the potato — who became scorbutic when that was struck off^ and reffained their health when it was restored. And I state it as the uniform result of my own experience and study of prison returns, that whenever the potato has been withdrawn by the authorities or refused by the individual, scurvy has- been the result. This important fact, then, may be added in when we sum up the benefits conferred upon us by the culture of the potato. Dr. Paris enumerates among its products '^ cottony flax," sugar, vinegar or spirit, a substi- tute for soap in bleaching, a most wholesome, nutritious, and economical vegetable, a starch no way inferior to Indian arrow-root ; and a valuable anodyne extract. To this catalogue I may add the well-known fact that potato- flour is deemed a necessary constituent of all fermented bread. But Dr. Paris saw in the potato a great political agent. He thought that it raised the population of Ireland from one million to seven millions in a century and a half. The potato famine had not then occurred to teach us that even such a boon as the potato was, and is, cannot be divested of a possible penalty. If Paris was right in ascribing the teeming population of Ireland to the culture of the potato, we cannot be wrong in ascribing this increase in part to its anti-scorbutic properties, by which 143 Symiptoms of the Scurvy. scurvy and its allied diseases must have been largely pre- vented J and the same must be true, in its degree, of the inhabitants of England and Scotland. There is a sense, then, in which we may be said to have fought our battles with the potato. Perhaps Louis XV. of France had some suspicion of this its prolific virtue, when he wore a bunch of its flowers among his courtiers on a festive occasion J and so brought fashion to bear with effect where philosophy for more than two centuries had utterly failed. Let us now look at this disease, scurvy, a little more closely. In the first place, let us guard against vulgar errors and misconceptions. Let it be well understood that scurv}"- is not a scurf or scab on the outer skin, nor a blush which the pressure of a finger will remove, nor a collection of red or white swellings like the nettle-rash, nor a something limited to the head or to some other part of the body ; but a collection of round spots or irregular stains, for which it is hard to find a better name than the old one of the London Bills, " the Purplesy These spots, or blotches, consist of dark blood poured out beneath the skin. This may be the only outward sign of the disease. But in severe cases the blood escapes into the very flesh of the limbs, making them stiff and painful 3 and the vessels are so weak that the slightest touch breaks them, and gives rise to every appearance of a bruise. The gums become dark, swollen, and spongy j the teeth get loose and fall out of their sockets ; the breath grows v^ery offen- sive J and blood pours from the mouth, nostrils, and eyes, and from every outlet of the body. At length the gums and the skin become the seats of foul ulcers, old wounds break out afresh, fractured bones long since repaired, are disunited ; and the poor sufferer, in full possession of con- sciousness, is reduced to such extremity of weakness that he will faint on the slightest exertion or least change of A Land and a Sea SciLrvy. 143 posture, and fall down dead as he is being carried on deck, within sight of the land to which, with its fresh air, fresh meat, fresh vegetables and fruit, he had been looking forward as his certain and speedy cure. To give a per- fect idea of the disease, we should have to add the drop- sical affections which mix with, or take the place of, the out-pourings of blood 3 we must recognise with worthy- John Woodall, the " poor miserable man, coming on land from a long voyage," " at the point of death," '' swollen to an exceeding greatness 5 sometimes not able to lift a \q^ over a straw," nor scarce to breathe, by reason of " strong obstruction." We should also have to note the association of scurvy with fever and dysentery 3 the spots of the spotted fever joined to the purples in the London Bills, and the smaller spots of the petechial fevers, being in a sense the manifestations of the scurvy, just as the dysentery, when it constituted the ''bloody jiux'' of the bills, owed its discharges of blood to the same cause. In a word, the defective diet of our London ancestry did doubtless bring about a scorbutic state which played a pro- minent part in more than one of their diseases. There is still another feature of the scurvy well worth noting. It was a disease especially liable to be aggravated by injudicious treatment. Thus Kramer, as cited by Sir Gilbert Blane (he was physician to the Imperial armies in Hungary from 1720 to 1730) "relates that of 400 men labouring under genuine scurvy, treated by one of the medical officers with mercury, so as to excite salivation, in conformity to the doctrines of his master, Boerhaave, not one survived." Now this terrible disease is sometimes looked upon as a sailor's malady j but this is an error. It is a disease of the land as well as the sea ; not the product of sea air or salt provisions. Nor were the diseases associated with it, as scourges of our fleets, peculiar to the sea. The foul 7 44 The Sairvy on Land. ulcers, dysentery, and fevers, like the scurvy itself, were all common among landsmen similarly circumstanced in respect of food, clothing, cleanliness, and ventilation. The scurvy was especially a disease of seamen, because, while they shared with soldiers, paupers, prisoners, nuns and monks, and the garrisons and inhabitants of beseiged cities, the evils of overcrowding, impure air, defective means of cleanliness, and scanty and tainted supplies of water, they were more frequently and constantly than landsmen exposed to the action of the true cause, an in- nutritious and otherwise defective dietary. I shall there- fore treat of scurvy, first as a disease of landsmen, then as it affects the sailor. Now the scurvy, though it may occur in warm climates is, as a rule, a disease of cold and temperate ones. It is common among the northern nations of the European continent, where the diet is very apt to fall short in vege- table elements, and it is accordingly endemic in Iceland, Greenland, Cronstadt, and the northern parts of Russia. Occasionally it has devastated whole kingdoms, as Bra- bant in the year 1556, and Holland in 1562. It has, doubtless, shown itself as a companion or consequence of famines and scarcities everywhere, especially in cold, damp seasons ; and, in the very nature of things, must have afflicted all nations at that stage of their progress from barbarism to civilization, when gardening and hor- ticulture were little practised, and commerce was in its infancy. In the London Bills, scurvy always found a place as a cause of death, and I think that it is easy to recognise it under the name of ''the purples" (associated with spotted fever prior to 1701, but from that date to J 728, heading a column of its own). In one year I find scurvy set down as the cause of 105 deaths; in another year " the purples " are credited with 56 ; and the diseases so commonly associated with scurvy (I mean The SciLi'vy at Quebec. 145 •dysentery and sores and ulcers) are conspicuous causes of •death. The worst form of dysentery, " bloody flux," caused in one year no less than 833 deaths; and sores and ulcers in another, 109. The ^' bloody Jiux'' disappears towards the end of the eighteenth century, being re- placed by simple flux, and it may be said of all the diseases I have just mentioned, that they disappeared from the Bills, or underwent great diminution with the march of time. But, as I have said, scurvy is not exclusively a disease of cold or temperate climates : for it occurred in the residency at Lucknow, and it attacked the gold miners of California on the overland journey and at the mines, when the thermometer, in the shade, stood above 100°. But these men, as Dr. Ober tells us, were working hard on a diet of fried bacon or fat pork, with wheaten cakes fried in fat, washed down by brandy or whisky, and copious draughts of strong coffee. Nevertheless it is in cold and temperate climates chiefly that the scurvy has appeared in its worst forms j in besieged towns, such as Thorn, Breda, Rochelle, and Stettin, in Gibraltar in 1780, at Kars and Sebastopol in our own times, and in Canadian garrisons. Lind tells us that, during the winter of 1 756, the English garrison at Oswego was so afflicted with scurvy, that among 700 men they often could not muster 80 fit for duty — a number scarcely sufficient to protect them from the Indians, and that 200 of the 700 died of the disease. Again, in the winter of 1759, ^^^^ scurvy broke out among the garrison of Quebec ; and these are the terms in which General Murray, the officer in command, speaks of the calamity : — " The excessive coldness of the climate, and constant living on salt provisions, without any vege- tables, introduced the scurvy among the troops, which, getting the better of every precaution of the officer, and 146 The Epidemic at Millbank. every remedy of the surgeon, became as universal as it was inveterate J insomuch that, before the end of April, a thousand were dead, and above two thousand of what remained totally unfit for any service." Sir Gilbert Blane cites Piiny and Tacitus as recording the outbreak of scurvy in tlie Roman armies. Thus did the scur\y do its work of destruction among our soldiers. We shall presently see what havoc it wrought among our sailors. But I must first give you some account of an out- break of scurvy that took place in the Millbank Peniten- tiary in 1822, though this history properly belongs to the first quarter of the nineteenth century. The prison was built on the Thames, on a piece of made ground, saturated with water, and surrounded by a tidal ditch. The river, a little higher up, received two of the largest of its foul tributaries, took in their waters at high tide, and, thus polluted, filled the ditch and soaked the soil. This water, improved by filtration, the prisoners drank. The building was opened for the reception of prisoners in i8i6. Six years later, tlie epi- demic which I am about to describe, occurred 3 but, in the two years and eight months preceding it, 1 1 cases of diarrhoea and dysentery, severe enough to be entered in the monthly sick reports, took place 3 and of these 6 were fatal. The tenants of this damp, foul spot, became, in the years 1822-23, the involuntary subjects of the follow- ing disastrous experiment : — Dr. Hutchinson, then medical superintendent, obser\^ing that the prisoners were not merely in high health, but even plethoric, deemed the diet excessive, counselled a reduc- tion, and submitted a reduced scale to the committee. But they foolishly preferred a dietary of their own, which came into operation early in July, 1822. It reduced the solid food from 304 to 168 ounces per week 3 it also Dysentery, Fever, and Nervo2LS Disorder. 147 lowered the meat element to i o ounces per week con- tained in the soup j and it struck off the potato element altogether. Now I infer, from a careful comparison of this with other dietaries, both of prisoners and paupers^ that this reduction in quantity, and in the meat element, was not adequate to the production of the epidemic that followed, even if we take into account the unhealthy site, the objectionable water supply, the cold winter that fol- lowed, and the low temperature of the prison cells at night. I believe that I am justified in ascribing the sick- ness that so soon followed the reduction, to the entire omission of the potato. Let us now look at the conse- quences. The new dietary came into use, as I have said, early in July, 18225 i" the autumn following, the prisoners grew feeble and languid, and a few slight cases of scurvy showed themselves j but in the months of February and March, 1823, scurvy, associated with diar- rhoea and dysentery, became so prevalent that more than half the prisoners were attacked, and by April 5th, 6 died of dysentery. All these diseases were cured by a reformed diet, and medical treatment 5 but the diarrhof;a and dysentery reappeared with great severity in the summer and autumn of 1823, in company with fever and nervous affections, so that the prison had to be closed for several months, and the prisoners to be removed. The severe nervous and mental maladies to which I have referred add a feature of peculiar interest to Dr. Latham's admirable account of the epidemic. The subject, in all its fulness and completeness, belong.^, as I have said, to the sanitary history of the first quarter of the nineteenth century. I treat it now as part of the history of land scurvy j and as an illustration, supported by many analogous occurrences, of the immense value of the potato as an element of all dietaries from which other vegetables, as well as fruits, are shut out. This simple L 2 148 OiLr Ships a Century ago. dietetic principle requires to be specially borne in mind in these days, when large establishments for the custody and care of paupers, prisoners, lunatics, aged persons, children at school, soldiers and sailors, and sick people, are so rapidly on the increase. I now proceed to treat of scurvy as it shows itself at sea, and among sailors. About a century ago, a vessel of war might seem to have been equipped and provisioned with a view to the production of the greatest possible amount of disease in the shortest possible space of time. Beef badly salted, and often so rotten that, before boiling it, it was necessar}^ *' to tie it round with cords ;" biscuits mouldy and full of " weevels or maggots j" and puddings of salt, suet, and flour, made up the dietary. The water was often so thick and green from decomposition and vegetable growth, and so offensive withal, as to disgust sight, smell, and taste. The ship was damp, filthy, and ill-ventilated, and the air of the wells so foul as often to produce fatal asphyxia. Personal cleanliness was neglected j the cloth- ing was insufficient, and the bedding too, the men having to turn in between blankets unwashed perhaps for a year ; little effort was made to amuse the mind, and none to instruct it ; the sailor's only luxury an exorbitant allowance of spirituous liquors, at sea, as on land, the fruitful source of disease, misery, insubordination, and crime. Add to all these privations and discomforts a dis- cipline not merely strict but severe, and punishment often inflicted at the instigation of momentary passion, and we have a lively and faithful picture of the naval service at the period to which I refer. This state of things was subject to slow and interrupted improvements 3 but Dr. Fletcher, a naval surgeon, writing in 1786, not only con- firms the sketch I have given in every particular, but adds to it some serious aggravations. When these foes of Ravages of the Scurvy. 149 health were doing their work, and scurvy, dysentery, and fever were reinforcing the enemy, we might suppose that power would be given to the captain or surgeon to procure a supply of the known remedies. But alas I red tape was as active and efficient in those days as we knew it to be in the Crimean War. Take this case, on Dr. Fletcher's authority, as an illustration : — " When his Majesty's ship the Roebuck, with some others, under the command of Sir Andrew Hammond, refitted at Antigua, there were a number of men attacked with yellow fever, &c.," *^sent to hospital." The doctor "was surprised to find that the sick were not liberally supplied with fruit, especially as oranges were plentiful and very cheap." But they were not given because " Government might possibly think such expense too great." He, there- fore, expended half a dollar a day on oranges for some thirty of the Roeluck's crew, with the happy result of quicker recoveries and fewer deaths than happened among the sick from the other ships. And this was no isolated occurrence 3 for the same authority tells us that a fleet might be stationed three years in the East, without the men being ever able to come at the fruits of the country ; a state of things which he justly compares to the strange practice of the ancients in prohibiting all kinds of drink to patients in ardent fevers. The consequences of the state of things I have been describing were, as you may suppose, eminently disastrous. Scurvy, putrid ulcer, malignant dysenter}^, and fever allied to that of jails (indeed, often directly imported from them, as testified by Howard and others) suddenly swept off the greater part of many ships' crews, and well nigh depopulated whole fleets. Scurvy alone, without any aid from the other diseases I have just named, has sufficed to place a well-manned vessel at the mercy of the winds and waves. Witness Anson's own ship, the 150 Warlike Miscarriages. CenturioTiy in i 742 ; when the crew were so weakened by it that had the ship been compelled to keep the sea a very few days longer, it could not have been brought to an anchor at Juan Fernandez, but must have gone adrift in the Pacific, the survivors perishing miserably, as once happened to a Spanish ship under the like circumstances ; or take the figures that express the mortality in Anson's fleet : — out of 961 men, 626 deaths in nine months, or very nearly 2 out of 3 ! And this was no rare or exceptional occurrence, for such things had happened in earlier and did happen in later times. Thus Sir Richard Hawkins, the great navigator of the age of Elizabeth and her suc- cessor, said that, in the course of twenty years he "had known of 10,000 seamen having perished by scurvy alone." Even so late as 1780, Sir Gilbert Blane found that a fleet manned with between 70C0 and 8000 seamen, had in one year lost one in every seven. Fortu- nately for us, this high mortality was not limited to our own ships ; a Portuguese historian, cited by Sir Gilbert Blane, speaking of the favourable case of an exploring expedition, says that " if the dead who had been thrown overboard between the coast of Guinea and the Cape of Good Hope, and between that Cape and Mozambique, could have had tomb-stones placed for them, each on the spot where he sank, the whole way would have appeared one continued cemetery." The disastrous consequences of this excessive sickness and mortality in time of war may be readily imagined, but it may be well to give a few illustrations : — I. Sir Francis Wheeler's expedition to the West Indies and North America, in 1693, consisting of two ships of the line and six frigates, miscarried in the attack on Marti- nique, through the force being weakened by diseases 3 and in his return voyage his crews were so reduced by deaths IlltLstrative Cases. 151 from scurvy and fever that there were hardly hands enough to bring the ships to anchor. 2. Admiral Hosier, employed with seven ships of the line in the year 1726, to protect the trade of the West Indies, buried his ships' companies twice over, and in place of quelling and coercing the Spaniards, was defied and insulted by them, and died of a broken heart. 3. To this excessive sickness and mortality Sir Gilbert attributes the failure of our arms in six general engage- ments of the Seven Years' War, and the American War, every one of which was a drawn battle, through deficiency of hands and want of strength in those who fought, due to excessive sickness and mortality. It was to facts such as these that Thomson alludes when he speaks of the diseases that "at Carthagena quenched The British fire." and pictures the " gallant Vernon" looking on "pitying" but helpless, at the terrible ravages of disease and death. And yet, even in those times, when other sanitary measures must have been either neglected or imperfectly carried out, there were not wanting striking examples of single ships and whole fleets maintained in perfect health and complete efficiency by fresh meat, vegetables, and fruit, or by strictly observing some dietetic precaution. I will give you one or two cases: — I. Fletcher tells us that he had been in a Channel cruiser when the water for above a week was more foetid than the very worst bilge-water, so that the men were *' obliged to suppress their sense of smeUing" when they used it J and yet their health was never better. They had fresh meat and vegetables. And he adds that when the Swallow was up the Ganges, and her water was taken in D^ Scurvy Prevented. under the most unfavourable circumstances, no complaint ensued^ " most assuredly owing to their supply of tea and fresh meat." What these unfavourable circumstances were, we learn from another passage, where he tells us that his ship was ordered three times up the Ganges in the very worst seasons j when the thermometer stood at 89°, when an exposure for a few minutes upon deck wetted them to the skin, when the dead bodies floated on the stream in such numbers that it was difficult to make a passage among them 3 and yet, on all these occasions, they left the river without losing a man j a result which Fletcher attributed solely to the tea and sugar which the men, taught by experience, bought each time they entered the river. 2. The same author gives us an instance on a larger scale, showing the preservative virtue of fresh provisions. It relates to the victory of Admiral Hawke, in 1747. 14,000 men, in 20 ships of the line and 12 frigates, had been pent up in their ships for six or seven months in the Bay of Biscay and on the coast of France j and yet, on the day of the tight there were not 20 sick sailors in the whole fleet J in the Royal George and in the Union, of 770 men, only I man unfit for duty ; and on board the Mars,. of 64 guns, not a sick person. " This most extraordinary degree of health is entirely attributed to the fleet having been well supplied w^ith fresh meat and greens 3" and he adds that, when the victualling transports were detained by contrary winds, and the supplies cut off^, they became very sickly. These are cases of scurvy prevented : here are instances of scurvy cured ; the first on the authority of Dr. Mead : — When Sir Charles Wager commanded the Baltic fleet, his sailors were terribly afflicted with the scurvy. But fortu- nately, he had taken in at Leghorn a quantity of lemons and oranges, and recollecting that he had often heard how effectual they were in the cure of the scurvy, he caused a Scurvy Citrcd. 153. chest of each (o be opened every day. The men ate the fruit, mixed the juice with their beer, and reached home in good health. Mr. Murray, a naval surgeon of large experience on board ship and in hospital, quoted by Lind, after speak- ing in high commendation of oranges and lemons as an infallible cure in every stage and species of the disease, if there was any natural strength left, and no flux, says that at the Danish island of St. Thomas 120 patients, in all the different stages of this distemper, were cured in little more than 1 2 days by limes alone, little or no other refreshments being obtainable. Lind gives us another instructive history, which I will present to you in a condensed form : — In the East India Company's first voyage, four ships were under the command of Captain James Lancaster. His ship had a crew of 202 men ; the three others, among them, 222. They left England about the i8th of April, and in July the scurvy broke out. " By the ist of August all the ships, except the captain's, were so thin of men, that they had scarce enough to hand the sails j and, upon having a con- trary wind for 15 or 16 days, the few who were well before began also to fall sick j" so *^ that the merchants who were sent " with " their caroroes," " were obligfed to take their turn at the helm, and do the sailors' duty, till they arrived at Saldania," where the crews of the three ships were in such a condition that they could hardly let fall an anchor, nor hoist out their boats, without the assis- tance of the captain's crew. And " the reason why his crew was in better health than the rest of the ships, was that, having brought some bottles of lemon-juice to sea, he gave to each sailor, as long as it lasted, three spoonfuls every morning fasting. " By this he cured many of his men, and preserved the rest." Having, in my last lecture, spoken of the efforts of 154 Ausons Expedition. Sutton and others to introduce fresh air into our ships, I must not omit to cite a fact which I lind in Fletcher's work : — The ships of the line. Prudent and Intrepid, sailed from England for the East Indies at the same time, and under apparently similar circumstances. " The Prudent, how- ever, lost three times as many men as the Intrepid : this at first seemed matter of surprise, till at length it was resolved into its proper cause. The Intrepid had scuttles cut between-decks, and the Prudent none, by which a free circulation of air was maintained in the Intrepid, when the lower deck-ports could not be kept open upon account of bad weather." The account I have given you of the scurvy, and the cases I have cited, will have prepared you to appreciate the history of the expedition of Anson, in 1 740, so often brought into comparison with Captain Cook's first voyage, in 1772. I have made a minute and careful analysis of the facts of Anson's expedition as given by Richard Walter, chaplain to the Centurion ; with the result, I am sorry to say, of destroymg another delusion, and compelling a material modification of the views which, in common with Sir John Pringle, Sir Gilbert Blane, and other good sani- tary reformers, I had been led to entertain. On the 1 8th of September, 1740, Anson set sail from St. Helen's 5 and, on the 15th of June, 1744, anchored at Spithead, having been absent from England three years and nine months. He left with six vessels of war, and two victuallers, and came back with his spoils, and a reputation richly earned, but with a single ship — his own Centurion. Our interest centres in three of these six ships — the Cen- turion, the Gloucester, and the Tryal, and the 961 men who formed their united crews. Such crews, we may hope, were never, before or since, brought together to tempt Providence and tr}^ the metal of a gallant commander. Of the seamen some were drafted direct from hospital and sick quarters. CalcfitiLvcs. ' 155 The land forces were men mostly sixty years old, some up- wards of seventy, the worst half of a batch of invalids, of whom the younger and more active had deserted. In lieu of the deserters, Anson was furnished with 2 10 " raw and undisciplined " marines, with *' scarcely more of the soldier than the regimentals." Some of these, too, had been lately discharged from hospital. I gather from facts stated in the narrative that Anson's own ship, the CejiturioJi, left England with a crew of 506 men ; of whom 79 were raw marines, and ^o aged invalids ; and I infer that the other crews were made up much in the same way. With crews composed in part of this ''aged and diseased detach- ment," "crazy and infirm," ''decrepit and miserable j" in part of raw undisciplined marines, did Anson start on his perilous expedition, at the worst possible season of the year, his ships so deeply laden as to oifer a serious impedi- ment to ventilation ; and with the knowledge that a Spanish fleet of greatly superior force was on the look-out for him. Now the part of the expedition in which we are inte- rested may be divided into four sea voyages and three sojourns on land : a run to Madeira, occupying 37 days; thence to St. Catherine's, 47 days ; thence to St. Julian's, 30 days ; and from St. Julian's to Juan Fernadez, 105 days — in all, 219 days at sea. Nine days at Madeira, 29 at St. Catherine's, and 10 at St. Julian's, make up a total of 48 days on land. From England to Juan Fernandez the time was 267 days, or somewhat less than 9 months. I will state what took place during this 9 months as briefly as I can. The run to Madeira occupied 37 days, instead of the usual lo or 123 and the crews sufl'ered from the fevers then known as Calentures. The Centurion lost two men. The ventilation being recognised as inadequate, 6 air-scuttles were ordered to be made in each ship, and a 6 Deaths on Board the Centurion. supply of water, wine, and other refreshments was laid in. The 47 days' run to St. Catherine's produced a serious sick-list -. 80 men were landed sick from the Centurion, of whom 28 died; and yet by the time they left the island, the 80 had become 96. These were em- barked, and in 30 days they reached Port St. Julian, which place, after a stay of 10 days, tliey left in good spirits, and, as I gather, in good health. It was the 1 05 days spent between St. Julian and Juan Fernandez, amid storms, cold, frost, and deluges of water, under unparalleled expo- sure, fatigue, and privation, that occasioned the greater part of the sickness and mortality of which I am pre- sently to give the summary. In about 10 days after leav- ing St. Julian the scurvy began to show itself, and in less than two months it had spread to such a degree that there were few on board free from it. Soon after, we read of 42 dying on board the Centurion, then in the month fol- lowing, double the number, and by the time the ship arrived at Juan Fernandez there had been a loss of up- wards of 200 men, and they could not '* muster more than six foremast men in a watch capable of duty," and even some of these were lame and unable to go aloft. I must not detain you with further details of the sickness and death on board the Centurion, or with the adventures of the Gloucester and Tryal. Suffice it to say that, in the short space of less than nine months, the time spent between England and Juan Fernandez, the crews of the three ships had lost 626 out of 961. Or, if we limit our- selves to the Centurion and its crew, concerning which we have the most exact information, it appears that, in less than 9 months, her 506 men were reduced to 214, her 50 invahds to 4, and her 79 marines to 1 1. Of this frightful mortality, by far tlie greater part occurred in the stormy and ever}^ way inclement weather, encountered in round- ing Cape Horn, in the two months and a half that elapsed Renewed A ttack of SciLvzy. 157 between leaving Port St. Julian and arriving at Juan Fernandez. It belongs to this sanitary history to state that at Madeira, St. Catherine's, St. Julian, and Juan Fernandez, the foul ships were refitted, cleansed, and purified, and that no sanitary precaution seems to have been neglected. Nor were these measures ineffectual, for we are told that for some time after leaving Juan Fernandez, the crews had "enjoyed a most uninterrupted state of health." But on leaving the coast of Mexico, the scurvy again began to show itself, and this time it was not possible to attribute it to the stormy and inclement weather, though that which they soon had to encounter doubtless added much to their sickness and mortality. At this time the crew of the Gloucester was reduced to 77 men and 18 boys, of which number only 16 men and 11 boys were able to keep the deck, and of these several were infirm. This ship had to be burnt, and her crew transferred to the Centurion. There were 70 sick among them, of whom '* 3 or 4 " died as they were being hoisted on board. And soon we find that the deaths of the consolidated crews were "extremely alarming," that no day passed that they did not bury 8, 10, or 12, and that "those who had hitherto continued healthy, began to fall down apace." When they were able to land on the island of Tinian, they put on shore 128 sick, many of whom were carried on the backs of the Commodore and his ofiicers. On that and the previous day, they buried 2 1 men, and i o more soon after. Anson himself, as we learn, did not escape the scurvy. This new attack of scur\'y occurred under circum- stances so different from the first as to puzzle the surgeon and the chaplain. They had fresh provisions in the shape of hogs and fowls, they caught fish in abundance, they had an ample supply of fresh water j they kept all 158 Fate of Pizarros Squadron. their ports open, " and took uncommon pains in cleansing and sweetening the ships." But no mention is made of vegetables or fruits, and they owed their supply of Mater to rains which must have kept the atmosphere moist, and so far unfavourable to them. The crews recovered their health at Tinian, and all that now remains of this sanitar}^ histor)'. is the simple statement that, when Anson came to muster the remnant of the united crews of the Centurion, the Gloucester, and the Tryal on board his own ship, prior to his attack on the Manila galeon, he had in all only 227 hands, of whom nearly 30 were boys, and 23 lascars and Dutchmen, besides other recruits picked up here and there. So that, out of the original 961 with which Anson left England, the sur\-ivors probably fell very far short of 200. Of the Spanish squadron of Pizarro, all that I have time to say is, that while our men were dying of scurv)', the Spaniards were perishing in large numbers of simple star\ation 3 and that out of a fleet of six vessels, with 278 guns, 2700 men, and a regiment of soldiers, the Admiral's vessel, the ^^ifl, alone sur^ ived, with a miserable remnant of 100 men. Need I add that all that part of this successful, though disastrous, expedition which does not relate to sanitar}' matters, constitutes a romance of real life which no Englishman should omit to read. It atlbrds a curious illustration throughout, of what skill, courage, and conduct can do to meet and overcome gigantic difficulties ; and, at the same time, it must be confessed, an example of the truth of the proverb which asserts that brave men are fortune's favourites. To pass through a hostile French fleet in a dense fog, with his treasure and remnant of brave men, was the crowning incident of an expedition which had abounded in happy turns of fortune. I prefaced this account of Anson's voyage by stating Captain Cook and the Royal Society. 1 59 that the close and careful study of it had led me to modify the views which, following the lead of Pringle and Blane, I had once adopted. I must now explain myself 3 and, in order that I may do so, I must remind you of a few facts relating to Cook's first voyage. He left England in 1772, just 32 years after the date of Anson's departure, was absent from England 3 years and 1 8 days, sailed round the world, and returned with the loss of 3 men by accident, and I by pulmonary consumption, out of a crew of 118. This was undoubtedly a most happy and favourable result, and we cannot be surprised that Captain Cook, being a Fellow of the Royal Society, should wish to tell that learned body how it had been brought about. This ac- cordingly he did in a paper addressed to the Society, under date March 5, 1776. This paper the Society honoured with the Copley medal, and Sir John Pringle, the President^ in presenting it (Captain Cook was then absent) pro- nounced upon the author and his work a well-deserved eulogium. In it he gave an excellent summary of Anson's expedition, and did the commander the justice of pointing out that the preparatory arrangements of the voyage were not made by himself j that his ship was so deep in the water that the ports could be opened only in the calmest weather 5 and that he neglected nothing for preserving the health of his men that was then known and practised in the navy. But the other serious drawbacks I have pointed out are not mentioned ; and the subject is so treated as to have led Blane and others to use Anson's disastrous failure as a standard of comparison by which to measure Cook's admitted success. Now the sketch I have just given of Anson's expedition, by showing you that the facts were even worse than they are usually represented to be, and by reducing the time within which the great destruc- tion of life took place, does but serve to strengthen the case as a sanitary lesson. But when all the facts are taken i5o Captains Mc Bride and Parry. together — tlie fact that it was a warhke, not an exploring, expedition j that tlie strange crews were forced upon him instead of being chosen by him ; that his ships were so built and fitted as to render ventilation most difficult j that he was sent out without any special provision being made for the health of his men at the very worst season of the year j that he encountered, in rounding Cape Horn, the ver}'- weather which compelled the greatest amount of exertion and exposure, rendered ventilation for many days together simply impossible, and by the union of cold and moisture was eminently favourable to the production of scuny 5 it must be obvious that we have here no fitting standard of comparison by which to measure Cook's merits and success. This being understood, we may give him all the praise his care and vigilance deser\-e. But, as this did not suffice wholly to prevent the scur\y, though it never failed to cure it, it is easy to imagine how the picture would have been reversed had Cook had to contend with Anson's disadvantages and difficulties. Though I have the most unfeigned admiration for Captain Cook, and am unwilling to say a word in his disparagement, I must observe that there were men before his time, as there have been since, who deserve the credit of the same con- scientious care, with the like happy results. As an instance of the first kind, take Captain McBride in the Jason frigate, supplied with malt as a preventive, and instructed by his brother's writings, two years and more at the Falk- land Islands, and losing only one man by apoplexy from intoxication 5 and, as an example of the second order, the exploring expedition of Captain Parry to the Polar seas. The Tiiry and Hecla, *' with no resources but what they carried with them," were absent from England 27 months, and though both men and officers suffered from scurvy, re- turned with a loss of only 3 men out of their united crews of 118 — the exact number of Cook's crew in the Resolution. Sanitary Reforms in the Navy, i6i It was Captain Cook's unquestioned merit, then, that gave him a foremost place among the promoters of sani- tary measures in the navy 5 but it was his connexion with the Royal Society, and the honour he received at its hands, that caused his name to be associated with the Scurvy as the man who, above all others, had illustrated the right methods of preventing and curing it. To have conducted an exploring expedition and 118 men round the world, through every variety of climate, during more than three years, with the loss of only one man by disease, was doubt- less a great achievement, honourable to himself" and the gallant service of which he was so distinguished an orna- ment 5 of a piece with his philanthropic life,, in kee])ing with his noble death. Captain Cook's first voyage may be looked upon as -one of those conspicuous illustrations of a great prin- ciple which have more than once given a much needed impulse to some great movement of reform. Such a movement, tending towards the improvement in the health of seamen was in progress through the greater part of the eighteenth century 5 promoted at one time by some fear- ful sacrifice of life, such as that which attended Anson's -expedition, at another by some signal success in preserving health, such as was Cook's first exploring voyage. The work was slow and interrupted 3 the lessons of experience were soon forgotten 5 the ruling powers were hard to move ; ^nd ventilation soon fell into disuse, in spite of all that had been done by DesaguHers, Hales, and Sutton. Lemon- juice, though recommended by Woodall, and actually sup- plied to merchant ships as early as 161 7, was not introduced into our navy till 1796, prior to which date navy surgeons had to supply medicines at their own cost. It was not till 1781 that what were called slop-ships (which may be briefly described as floating baths-and-wash-houses, and •clothing establishments, by which recruits and pressed i62 Mil and j^tk Centuries compared. men might be passed on into the senice in a decent and healthy condition) — it was not till 1781 that these were substituted for small tenders and receiving ships. It was not till late in the century that improvements were made in "the situation, htting, and furniture of the sick-lerthy The separation of the sick from the sound, measures for cleansing and dr}ang ships, the use of preser\ed meats, the substitution of wine and tea for spirits, the employment of quicklime for purifying the water taken on board, the supplemental use of distilled water, the promotion of per- sonal cleanliness by inspection at stated periods — these, and other obvious sanitary ameliorations and precautions, assisted by many improvements in the construction of vessels (such as copper-sheathing, tirst introduced into our nasy in 1 761), came gradually into operation 3 and with vaccination, and the supply of lemon-juice, must have greatly improved the health of our sailors by the end of the eighteenth century. It is the period preceding the end of the eighteenth centur}^ then, that we must bring into comparison with the early years of the nineteenth, when our ships were fully supplied with all the means and appliances of health, if we would understand and appre- ciate the value of sanitar}^ science. These are the facts as given by Sir Gilbert Blane. In 1779, 70,000 men were voted for the ser\'ice of the navy 3 of these 28,592 w^ere sent sick to hos- pital, and 1658 died. In 1813, out of just twice the number (140,000), 13,071, were sent to hospital, and 977 died. In 1779, therefore, the sick were more than 2 in every 3, and the deaths i in every 42 j while in 1813, the sick were about 2 in 21, and the deaths i in 143, the sickness reduced to a fourth, the deaths to little more than a third ! I will give you one other numerical statement. I extract from one of Sir Gilbert Blane's tables all those Increased Efficiency of the Navy. 163 years in which the number of seamen and marines voted by Parliament was the same, namely 120,0005 and I give you the sick for those years. They form, as you see, a descending series : — 20,544 in 1797, 15,713 in 1798, 14,608 in 1799, 8083 in 1805, 7662 in i8o(5. Or, take a similar comparison where the numbers voted were in each year 100,000 : the years 1782, 1795, and 1804. The figures for the sick are 22,909, 20,579, 7650. These figures speak for themselves 5 they are very elo- quent. I will add, from the same authority, a statement of a more general kind. The Channel fleet, in the year 1800, kept the sea for four months without one vessel being in port, and brought back only 16 subjects for hospital 3 while only twenty years before, the same fleet was so overrun with scurvy and fever as to be unable to keep the sea for ten weeks together. Is it possible to imagine a more conclusive demonstra- tion than these facts afford of the reality and importance of the science and art of hygiene r If it be true, as it undoubtedly is, that by improvements in diet, water- supply, and ventilation 5 in clothing and cleanliness ; aided by superior medical treatment, and especially by vaccination 3 and by an improved discipline, tempered by mental culture and amusement — if it be true that these improvements and reforms have saved life and prevented sickness to such an extent, that the eflfective force of our navy has been more than doubled, that one ship, for every purpose of navigation and warfare, is at least equal to two of the same size and force, that a vessel can now keep the sea for twice or thrice the time that was pos- sible less than a century ago 3 if it be true that, at the old rate of mortality, all Europe could not have furnished the seamen necessary for our defence and safety during the great revolutionary war : then is it a mere waste of word-s to argue that health, which is the strength of all who M 2 164 Increased Efficiency of the Army. work, is the great source of power to nations in their peaceful labours, as in their warlike struggles. I have devoted the greater part of this lecture to the navy, because the facts connected with that branch of the public service are more demonstrative of the efficacy of measures of prevention in rooting out the Scurvy than any which the records of the army afford. But you will infer from what I have said of Scurvy as it shows itself on land, especially in besieged places, that the knowledge we have acquired by the study of the disease as it occurs at sea has not been lost on those whose duty it was to promote tlie health and efficiency of the army. 163 LECTURE VII. THE JAIL-DISTEMPER, This lecture will be, from beginning to end, a Romance of History. I shall first give you some account of a singular disease, fatal to individuals, disastrous to the State, and believed to have been peculiar to the prisons of England. I shall then lay before you a description of the condition of our prisons a century ago, which, if it were not strictly true, would be simply incredible. This done, I shall tell you by whom and by what means that state of things was reformed and amended ; and lastly, I shall give a sketch of the life and acts of John Howard, of which life and acts, as of the abuses he reformed, it may be said that they too, if not true would be incredible. The jail-distemper, of which I am to treat in this lecture, is a very ancient malady. Howard, on Stow's authority, traces it as far back as the year 1414, when " the gaolers of Newgate and Ludgate died, and prisoners in Newgate to the number of sixty-four." Dr. Robert Williams, in treating of the typhoid poison, cites a passage from Wood's History and Antiquities of Oxford, to the effect that a contagious fever " broke out at the assize of Cambridge, when held in the castle there, in the time of Lent, 13 Henry VHI., 1521-1522. For the justices there, and all the gentlemen, bailives, and others resorting thither, took such an infection that many of them died, and almost all 1 66 The Black Assize at Oxford. that were present fell desperately sick, and narrowly escaped with their lives." To these early notices it is usual to add Lord Bacon's testimony that "The most per- nicious infection, next to the plague, is the smell of the jail, when prisoners have been long, and close, and nastily kept j whereof we have had in our time experience twice or thrice ; when both the judges that sat upon the jail, and numbers of those that attended the business or were present, sickened upon it, and died." Next in order of time to the outbreaks of 141 4 and 1521 comes the notorious Black Assize at Oxford, in 1377. I quote from Holinshed. At the assizes held the 4th, 5th, and 6th days of July, one Rowland Jenkes was arraigned and condemned " for his seditious toong," "at which time there arose amidst the people such a dampe" (an old mining expression) " that almost all were smouldered, very few escaping that were not taken at that instant :" " the jurors died presently, shortly after died Sir Robert Bell, Lord Chief Baron," with twelve others whose names are given. There died in the town of Oxford 300 persons, and there sickened there, but died in other places, 200 and odd from the 6th of July to the 1 2th of August, after which day there died not one of that sickness, for one of them did not infect another, nor did any one woman or child die of it. We learn further that the disease was attended by haemorrhages ; and " that those that bled till they died, strove so much with their sickness, that the blood issued out of their vents : but yet had perfect memory, even to the yielding of tlieir breath." The account given by William Martin confirms this 3 and he adds, " all that were present, almost every one, within 40 hours died, except women and children, and no others were touched with the contagion." This Black Assize occurred, be it recollected, in 15773 and it is to this period that another statement quoted by Howard from The Black Assize at Exeter, \ 67 Stow's Survey relates. Speaking of the King's Bench Prison, he tells us '* that in the six years preceding the year 1579, one hundred prisoners died there, and twelve between Michaelmas and March of the last mentioned year," "through a certain contagion called the sick?it'ss of the house.'' The jail-distemper must have been very rife in the last quarter of the sixteenth century 5 for it showed itself not only at Oxford and in London, but also at Exeter. The date of its outbreak in this city was March 14, ij86, and the occasion was the city assizes held before Sir Edmund Anderson, Lord Chief Justice of the Common Pleas, and Serjeant Floredaie, a Baron of the Exchequer. Holinshed, from whose chronicles I extract this account, describes it as a very sudden and strange sickness, appearing first among the prisoners of the gaol of the castle of Exon, from whom it was dispersed, upon their trial, among sundry other persons. It was very sharp for the time, and few of those first attacked escaped. It was contagious ajid infectious, but not so violent as the plague commonly is J and there was no outward ulcer or sore. There were various opinions as to the cause of the disease. Some attributed it to the "contagion of the gaol," the " close air" and " filthy stink" of which soon affect most prisoners " newly come out of the fresh air." "This is commonly called the gaole sickenesse, and many die thereof." Others imputed the disease to "certaine poor Portingals," about eight and thirty in number, whom one Barnard Drake had captured at sea, and brought into Dartmouth haven, whence they were sent to the castle gaol, and " cast into the deepe pit and stinking dungeon." These men had been long at sea, in a ship from New- foundland, laden with fish ; without change of apparel, and without beds to lie upon. Most of them were sick, some died, and " some one of them was distracted." This i68 OtJicr OiUbj'eaks of the jail-Distcmpcj'. sickness soon spread among the other prisoners, of whom many died and the rest ^' hardly escaped." Many of these prisoners when brought to trial were so weak that they had to be led, or carried from the jail on hand-barrows ; and the sight of them, more like *' hunger- star\-ed than with sickness diseased," moved the Lord Chief Justice and others to pity, and to certain reforms and improvements. The prisoners, after being rested and kept for a time in tlie air, were brought into court, when an "infection followed " upon many that were there, and especially upon such as were nearest. The effect was not immediate, for ewevy one went away in as good health as he came ; yet, after a few days, the disease showed itself, and more died than escaped. Many of the sufferers were of ''good account," and the list comprises several names now well known in the county. Of the common people also, many died ; and especially constables, reeves, and tithing- men, and jurors, and ''namely, one jury of twelve, of which there died eleven." This sickness was dispersed through the shire, and was not extinguished in October, 1586, when this account was written. The period of incubation, as we should now call it, was fourteen days or more, but some, we infer, must have sickened in "a few days." Its moral effects^ are thus described. At its lirst coming it frightened the people, and led many men to pretend, rather than to perform, amendment of life. " So long as the plague was hot and fervent, so long every man was holy and re- pentant : but with the slaking of the one, followed the forgetfulness of the other." Three considerable outbreaks of jail-fever occurred in the eighteenth century — in the interval between the years 1730 and 1750. The first at Taunton, in 17.30 j the second at Launceston, in 17425 the third in London, in. The Black Assize in London. 169. 1750. The Taunton case is mentioned by Howard, in these words. " At the Lent assizes, in Taunton, in 1730^ some prisoners, who were brought thither from Ivilchester gaol, infected the court; and Lord Chief Baron Pen- gelley. Sir James Sheppard, serjeant 3 John Pigot, Esq., sherift^ and some hundreds besides, died of the gaol dis- temper." Of the outbreak at Launceston, Huxham gives us some interesting particulars in his " Observations on the Air and Epidemic Diseases," for April, 1742. The disease was " a contagious putrid fever," " very pesti- lential," both exhausting and oppressive; attended with tremblings, twitchings, restlessness, delirium ; with early phrensy and lethargy in many instances. The tongue was dry and black, the breath offensive, and the skin spotted with black petechiae. An offensive diarrhcna *' brought numbers to their end." This fever ''took its rise from prisons, was disseminated far and near by the county assizes, occasioned the death of numbers, and foiled frequently the best advice." "Those who bled too pro- fusely killed the patient infallibly, and not the disease." Huxham saw three cases of this fever. One patient, a gentleman, died on the 13th day from his seizure, " stupid, delirious, and covered over with purple spots and livid pustules." I take my account of the jail-distemper of 1750 from Sir John Pringle's " Observations on the Jail or Hospital Fever." " Li the year 1750, on the nth of May, the sessions began at the Old Bailey, and continued for some days ; in which time there were more criminals tried, and a greater multitude was present in the court, than usual." The prisoners, about a hundred in number, were crowded into two rooms, measuring 14 feet by j 1, and 7 feet high,, and in the bail-dock (a small corner enclosure, open at the top), into which were put some who had been under the closest confinement. The court itself was about 30 feet 1 70 Other Black Assizes. square ; and into this narrow and crowded space the air from the bail-dock and the two small rooms found easy access. An open window, "at the furthest end of the room from the bench/' occasioned a draft in the direction of those who were found to have suffered most. These were the persons on the bench, of whom four were attacked and died, namely. Sir Samuel Pennant, the Lord Mayor 5 Sir Thomas Abney and Baron Clarke, judges j and Sir Daniel Lambert, alderman. The other victims were two or three counsel, an under-sheriff, several of the Middlesex jury, and others, to the amount of above 40. This list is exclusive of persons of a lower rank, and of those who did not sicken within a fortnight. "This sickness, as far as was known, spread no further." Sir John raises the question, " whether the air was most tainted from the bar by some of the prisoners then ill of the jail-distemper, or by the general uncleanliness of such persons?" But bethinks it " probable that both causes concurred." The sufferers are said to have " soon become delirious," and several to have had spots upon the skin. The fever was extremely fatal. "All that were seized with the fever died, excepting two or three at most." Such is Pringle's account of the sixth and last of the Black Assizes. It differs in one or two points from tlie notice of it at p. 102 of Murchison's treatise on the " Continued Fevers of Great Britain," to which I refer you 3 but it is all that is needed for my present purpose. Now, there is reason to believe that these Black Assizes were a few only of many similar outbreaks of which we have no detailed accounts ; for it is highly improbable that a disease which showed itself thrice in the sixteenth cen- tury and thrice in the eighteenth, should have had no exis- tence in the interv^al between 1586 and 1 730. And this view of the case is confirmed by what Lord Bacon says of the disease. There had been in his day "■ experience twice or y4 Black Assize in Dublin, 171 thrice " of this jail-distemper j and Dr. Lettsom, writing in 1774, refers to "some recent instances at the Old Bailey-j and in the last Lent circuity" and to "the fatal transaction at Salt-hill." Let me here observe that, though I began this lecture by speaking of the jail-distemper as peculiar to the prisons of England, I did not wish to ignore the fact that it has been known to occur in Ireland too. Thus I find in the '^Gentleman's Magazine" for 1776, that, " In Dublin a malignant fever, occasioned by a criminal infected with the jail-distemper being brought into the Court of Sessions without cleansing, produced very fatal effects, and alarmed the whole city." The names of eight of the victims are given, besides several attorneys and others who had to attend in court. The jail-distemper, then, on many occasions, made the legal service of the State a service of danger j bat the mis- chief did not end here: it interfered with the due course of justice by the terror it inspired. Thus, I find it stated in the " London Packet," under date March 25, 1774, that an "invidious report" that " the gaol distemper prevailed at Launceston having been spread abroad, great pains were taken to disabuse the public, and two of the faculty were sent to Exeter to state on oath that no such distemper prevailed there. But the judges were afraid to see them, and the gentlemen of the bar, alarmed by the recent death of Baron Adams, attributed to the fever, retired, some to Bridgwater, others eastward 3 so that Judge Aston had to adjourn the court." Thus did the jail-distemper do its work of destruction and disorganization in our courts of law. Let us see how it conducted itself towards the general population of the country. I. Howard tells us that " At Axminster, a little town in Devonshire, a prisoner discharged from Exeter Gaol 1J2 J ail' Distemper spreads among tJie People. in 1755, infected his family with that disease j of which two of them died, and many others in that town after- w^ards." 2. At page 26 of the " Medical Memoirs of the Gene- ral Dispensary," it is stated that a prisoner dismissed from Newgate, apparently in tolerable health, in four days afterwards was seized with the symptoms of a mahgnant fever, and infected eleven persons who were attacked by the same disease the next week. He was thought to have received the infection before he left Newgate j but he re- tained the clothes he had worn there. 3. Mr. Field, chaplain of the Reading County JaiJ, gives the following incident, from the diary of the Rev. T. Scott. In 1780, a baker living at Stoke, in Buckingham- shire, allowed a poor man with a large family, to contract a debt of 10?., and then arrested him, thinking that the overseers would pay the sum rather than let him be thrown into prison. But they disappointed him. The debtor was sent to Aylesbury jail, where the fever then prevailed, and took the disease. His wife went to nurse him j he died. She returned home, sickened, and died. The malady spread in the village, sparing the children, but proving fatal to the parents. Forty children were believed to have been bereft of one parent, and nearly twenty of both. The same fever had broken out at Northampton as well as at Aylesbury. 4. In these three instances, the jail-distemper was com- municated to the outside population by the discharged prisoner himself. I add one instance in which, like tlie plague of old and the small-pox, the disease was carried in the clothes. A man of the name of Russel, whom Dr. Lettsom attended in Wood Street Compter, died of the gaol fever : he had a large family, who lodged near Fleet Market ; and after his death his widow took his clothes there, and probably used some of them j for, about a week Infects our Armies and Fleets. 1 73 after, *' herself and the whole family were attacked with a malignant, or jail fever, and with difficulty survived." This jail-distemper, which thus infected our civil popula- tion, was one of the worst scourges of our armies and fleets. Pringle tells us that " gaols have often been the cause of malignant fevers," and that, in the rebellion in Scotland, above two hundred men of one regiment were infected by deserters brought from English prisons 5 and this is not the only instance he gives. To the same effect is the evidence of Lind as to the importation of the jail -distemper into our fleets. Howard states that he showed him, in a ward of Haslar Hospital, a number of sailors ill of the jail fever, brought on board their ship by a man discharged from a London prison ; and Lind, in his work on the Health of Seamen, asserts that ** the sources of infection to our armies and fleets are un- doubtedly the gaols 5" that the disease could often be traced directly from them 5 and especially in impressing men on the hasty equipment of a fleet. "The first English fleet sent last war to America, lost by it above '2000 menj" and Lind elsewhere assures us that ** the seeds of infection were carried from the guard-ships into our squadrons ; and that the mortality thence occasioned was greater than by all other diseases or means of death put together." Howard gives us some cases of destruction of life among soldiers on a smaller scale. In his visit to the county jail, Chester Castle, he inspected some cells, one of which, when the door was shut, brought to his mind the Black Hole at Calcutta. An officer at Worcester told him that having sent a sergeant and two men for two deserters lodged here, three of them died a few days after they came to their quarters. And of the Savoy, in which military prisoners were confined, he reports thus in March, 1776: **I saw many sick and dying. The gaol was so 174 TVood Street Covipter, infected by them, that the distemper has been caught there by many since." Again, in May of the same year, he says : " Many of them sick of the gaol distemper in the rooms where I saw the sick and dying in March." But this is not all. The prison lists, as given by Howard, often contain the significant entr}', '' impressed men." I find it in eleven instances. The number of such prisoners was 77. Thus in ever}' possible way was the jail-fever brought to bear on our army and navy. Our soldiers and sailors were taken to it, and it was, in turn, carried to them. Having now shown you how the jail-distemper invaded our courts of law, spread among the population of our towns and villages, and infected our armies and fleets, I proceed to describe the places in which the disease was born and bred. I must premise that in Howard's time the majority of prisoners were debtors. In 1779 there were 2076 debtors to 804 felons, Sec, 909 petty offenders, and ^26 prisoners in the hulks. In Wood Street Compter, from which I take my first illustration, there were, at that date, 38 debtors and 11 described as felons, &c. Of the debtors 6 were women. Well ! five years before this date, this prison was in the state I am now to describe. There was a room in it known as "the common side," 12 feet high, '^'^ feet long, and 15 feet wide, within the bare walls. The beds were piled one above another " in little separate- cabins," the access to the uppermost tier being by a ladder. The room had a door, and a chimney, and near the door two windows, usually kept shut, and looking into a dark entrance. The victuals were dressed by a large fire in this room, which is described as " capable of holding above 40 prisoners." If we take the number at 40, and make no deduction for the beds, the cubic space per prisoner would be less than 150 feet. Well might Lettsom say that if the projector of this apartment had exerted his utmost ability The King's Bench. 175 he " could not have planned a place of the same dimensions more effectually calculated to destroy his fellow-creatures." The City of London had so neglected its duty towards these poor creatures, that when they fell ill not even an apothecary was engaged to attend them. The Governors of the General Dispensary supplied this want 3 and during the year 1773, Lettsom attended eight patients with the jail-fev'er, of whom two died : one of the two being the man Russel whose clothes infected his family. When Howard visited this place, the keeper told him that " in the beginning of the year 177.3 his prisoners were sickly, and II died." That this Wood Street Compter was no exceptional case, you will infer from the extracts I have made from the Report of a Parhamentary Committee on the State of the King's Bench, presented to the House in this same year 1773 5 you will find the Report in the Commons Journals, 13 Geo. HI., p. 123. It states among other things that on account of the number of prisoners being always greatly in excess of the number of rooms, the marshal had permitted many to lie in the chapel, in the tap-room, on the staircases and benches, and other improper places, by which means they contract disorders, which often prove fatal, not only to themselves, but to the prisoners in general 3 that there are no separate apartments for sick prisoners, no place for the confinement of the riotous, nor any stronghold for prisoners committed for capital offences j that the walls of the prison are so low and thin that prisoners often escape over and through them 3 and '' that prisoners have been known to break through in less than half an hour." The petition of Benjamin Thomas states that the prisoners took the rooms by seniority, and had to wait many months for them, during which time they were '' obliged to con- tract with some old indigent prisoner for a lodging at an exorbitant price." T76 Coiuity and BoroiLgh Jails. These two examples will give yon an idea of the state of prisons in London about the year 1 774. I will now give one or two illustrations of the condition of prisons and bridewells in country places from the pen of Howard. J . Dartford County Bridewell. — " No chimneys 3 offen- sive sewers j and the rooms dirty ; no water, no straw ; no court." "The keeper told me, they had about two years ago a bad fever, which himself and family and every fresh prisoner caught. Two died of it." 2. Cambridge Town Bridewell. — ''In the spring ot 1779, seventeen women were confined in the daytime, and some of them at night, in a room 19 feet square, which has no fire-place or sewer. This made it extremely offensive, and occasioned a fever or sickness among them which alarmed the Vice-Chancellor, who ordered all of them to be discharged. Two or three died within a few days." 3. Marlborough County Bridewell. — All the rooms are on the ground-floor j and, by a sewer within doors, are made very offensive, " especially the men's night-room, in which, when I was there first, I saw one dying on the floor of gaol-fever. The keeper told me that, just before, one had died there, and another soon after his discharge." 4. County Gaol, Launceston. — " The prison is a room or passage 23 1 ft. by 7^^ ft., with only one window, 2 ft. by I J ft., and three dungeons or cages on the side oppo- site the window ; these are about 6 J ft. deep ; one 9 ft. long, one about 8 ft., one not 5 ft. — this last for women. They are all very offensive ; no chimney, no water, no sewers, damp earth floors, no infirmar)^, the court not secure, and prisoners seldom permitted to go out to it. Indeed the whole prison is out of repair, and yet the gaoler lives distant. I once found the prisoners chained two or three together. Their provision was put down to them through a hole (9 in. by 8 in.) in the floor of the room above (used as a chapel), and those who served Deprivation of Watery Air, Light. 177 them there, often caught the gaol fever. At my first visit, I found the keeper, his assistant, and all the prisoners but one, sick of it 5 and heard that, a few years before, many prisoners had died of it, and the keeper and his wife, in one night." This is just the sort of place in which the infection of the Black Assize of 1 742, described by Huxham, is likely to have originated. And now, having illustrated the state of our prisons, in town and country, I will give you a condensed account of it, taken from the materials so laboriously and conscien- tiously collected by Howard, and chiefly in his own words. "Many prisons," he says, "'are scantily supplied, and some almost totally unprovided with the necessaries of life." " Many prisons have no water j" ** in some places, where there is water, prisoners are always locked up within doors, and have no more than the keeper or his servants think fit to bring them j in one place they were limited to three pints a day each — a scanty provision for drink and cleanliness ! " "And as to air . . . given us by Providence quite gratis . . . methods are contrived to rob prisoners of this gtnuine cordial of life, as Dr. Hales ver}^ properly calls it." So foul was the air of the jails, that Howard's clothes, in his^r^^ journeys, were so offen- sive that he could not close the windows of his post- chaise, and was, therefore, often obliged to travel on horseback. And he tells us that the leaves of his memo- randum-book were often so tainted, that he could not use it till after spreading it an hour or two before the fire ; and that even the phial of vinegar, which he thought an antidote, after using it in a few prisons, would become "intolerably disagreeable." He adds, "many gaolers made excuses, and did not go with me into the felons' wards." The supply of light was not more liberal than that of air and water — a circumstance which Howard N 1 78 Prison Sipialor and Destitution. accounts for by ^' the window-tax which the gaolers have to pay 3 this tempts tliem to stop the windows, and stifle their prisoners." Thus scantily supplied with water, air, and light, die prisoners literally rotted in "close rooms, cells, and sub- terranean dungeons," of which this is no exaggerated description : — " In some of these caverns, the floor is very damp J in others, there is sometimes an inch or two of water J and the straw, or bedding, is laid on such floors, seldom on barrack bedsteads. Where prisoners are not kept in underground cells, they are often confined to their rooms, because there is no court belonging to the prison." " In many gaols, and in most bridewells, there is no allowance of bedding or straw for prisoners to sleep on ; and if by any means they get a little, it is not changed for months together, so that it is almost worn to dust. Some lie upon rags, otliers upon the bare floors. When I have complained of this to the keepers, their justifica- tion has been, " the county allows no straw ; the prisoners have none but at my cost." " Some gaols have no 3EWERS " (a term used to designate conveniences for the reception and discharge of ofl'ensive matters), " and in those that have, if they be not properly attended to, they are, even to a visitant, ofi^ensive beyond de- scription." Then as to food : — It may be said, with truth, that most prisoners were half-starved ; and Howard tells us that in above half the county jailsy the " debtors have no bread, although it is granted to the highwayman, the housebreaker, and the murderer ; and medical assistance, which is provided for the latter, is withheld from the former." But though wholesome food and necessary medicine were withheld from the poor debtor, he might have as much spirituous liquor as he could contrive to earn or beg. And it was a well-known fact that, in most Prison Danoralization. prisons, charitable gifts were expended in this way j while there is good evidence that, in some, the personal doles of the visitors, who were allowed to see the debtors at certain hours on certain days, were intercepted by men and women introduced from without to personate them j and, if the begging was done on the premises by a box for contributions, the few pence collected were distributed among those only who had qualified themselves after sooic such fashion as that in force at Whitechapel prison for debtors. The qualification was an entrance fee to the jailer of is. 6d., and a treat to the prisoners of half a gallon of beer. So that, in those evil days, the gifts in- tended for the poor fell into the hands of the profligate, and money which should have relieved distress, found its way to the prison bar. This cruel farce performed in those times within prison walls, is, in our days, exhibited in the open street. The mendicant-thief intercepts the charity intended for the poor, and spends it in the gin- shop. This repulsive picture of prisons and prison-life a cen- tury ago, admits still of some heightening touches. The prisoners, like Goldsmith's " Vicar of Wakefield," were allowed to have their families about them ; for Howard tells us, that " debtors croiud the gaols (especially those in London) with their uives and children. There are often, by this means, ten or twelve people in a middle-sized room J increasing the danger of infection, and corrupting the morals of the children." Elsewhere, Howard com- plains of " the confining all sorts of prisoners together, debtors and felons, men and women ; the young begin- ner and the old offender 3" and, again, of "the number of men in the same room, and of lewd women, admitted under the name of wives j" and of *' lunatics at large in some prisons, disturbing and terrifying the other pri- soners." N 2 3 8o Prisons Private Property. All these evils and abuses were carried to an extreme in jails that were private property, the keepers being pro- tected by the proprietors, and less subject to the control of the magistrates. Now it is an eminently curious and instructive fact that some of the worst conditioned jails were the property of noblemen and Church dignitaries. Among the noble, reverend, and right reverend pro- prietors, we iind Lords Salisbury, Exeter, Arundel, and Derby ; the Marquis of Carnarv^on j the Earl of Cholmon- delcy ; the Dukes of Portland, Devonshire, Norfolk, and Leeds 5 the Bishops of Salisbury, Ely, and Durham 3 the Dean and Chapter of Westminster j and Christ Church College, Oxford. I subjoin three sketches of these private jails. One of them, Howard tells us, " was quite out of repair and unsafe 3 and the proprietor, not choosing to repair it, the gaoler, to confine his prisoners, took a method that, to all who saw it, was really shocking." Respecting the second of these jails Howard is more explicit J for he says that some years before that, a prisoner w^as tormented with thumbscrews ; and that one of the grand ]\iry (Howard's informant) remonstrated with the proprietor, but in vain. My third illustration is given in greater detail. The prison of Ely was the property of the Bishop, Lord of the Franchise of the Isle of Ely. " It was in part rebuilt by the late bishop, about fourteen years ago ; upon com- plaint of the cruel method which, for want of a safe gaol, the keeper took to secure his prisoners. This was by chaining them down on their backs upon a floor, across which were several iron bars, with an iron collar with spikes about their necks, and a heavy iron bar over their legs. An excellent magistrate, James Collyer, Esq , presented an account of the case, accompanied with a drawing, to tlie King, with which his Majesty was Extensive Prevalence of the Disease. 1 8 1 much affected, and gave immediate orders for a proper inquiry and redress." I will give you one more illustration of the same class, partly to show that the titled owners of these squalid properties, or those who acted for them, demanded a very handsome rent, and partly for the sake of the complete picture it affords of the consequences, inside and outside the prison, of the then system of imprisonment for debt. The prison in question is Chesterfield jail, the property of the Duke of Portland. It consists of " one room with a cellar under it, and the gaoler pays for it i8/. 125. a year. The cellar has not been cleaned for many months, nor the prison door opened for several weeks. The prisoners occasionally descend to the cellar through a hole in the Hoor. There is no allowance, no straws no firing, and water is put in at the window at the price of a half- penny the three gallons." Howard finds four prisoners here, who tell him that they are half starved, and one of them says that he has not eaten a morsel the whole day, though it is afternoon. Their meagre, sickly countenances confirm what they say. All have wives, and their fa- milies amount to thirteen children, cast on their respective parishes. Two had their groats (the legal allowance) from their creditors, and these relieved the other two. Such being the places in which the jail-distemper was bred^ it will be interesting to know in how many of them it was either witnessed or heard of by Howard, when he inspected our prisons in the few years following 1774. By marking those prisons, which he describes with some degree of detail, and noting in which of them he saw the jail-distemper, and in which he heard of its having re- cently prevailed, I find that out of 105 prisons he wit- nessed it in 6, and heard of it in 21. So that, putting the two figures together, we may reasonablv infer that the disease haunted one-fourth at least of orr jails. That 1 82 The y ail'Fever in France : destructive diseases, and probably the jail-distemper, pre- vailed ill prisons under direct Government control will be inferred from what Howard says about the hulks on the Thames. It resulted, he says, from a public inquiry, that from August, 1776, to March 26, 1778, out of 632 prisoners 1 76 had died. This is much more than i in 4. I stated at the beginning of this lecture that the jail- distemper was believed to be peculiar to the prisons of England, and for this statement I had the authority of John Howard, who arrived at that conclusion after visiting the clean prisons of Holland, and the less clean, or emi- nently dirty and offensive prisons of Germany, Italy, Switzerland, Austrian and French Flanders, and France : and receiving from Russia what he deemed trustworth}- information. But Howard was deceived in respect of France, and possibly of some other countries by the misuse of terms. Speaking of the Grand Chatelet in Paris, Howard says that a contagious disease prevailed there which in France they call le scorlut, the scurvy. ''This distemper was found to proceed from the prisons ; and to spread in the Hotel Dieu, whither prisoners that had it were removed. The cause of it was generally thought to be want of cleanliness in prisons, where several of those confined had worn their linen for many months, and in- fected the most healthy new-comers that were put in the room with them. Eight hundred were ill of it at once in the hospital of St. Louis, to which all that were sick of it in the Hotel Dieu had been carried." In the Bicetre, Howard found "' an infirmary for the scorlut, a distemper very common and fatal among them. There were 6^ patients, most of them ill of this disorder. They contract it in a year or two from their confinement, as they are never suffered to go out of their rooms. Many lose the use of their limbs by it. I saw several such miserable ob - Generally a Form of Typhus. \ 83 jects at St. Louis's Hospital, where they are often admitted at the expiration of their term at the Bicctre." This must have been a terrible addition to tlie horrors of French hospitals, such as Howard saw them, and Frenchmen themselves have described them. Speaking of St. Louis and L'Hotel Dieu, Howard says that they were the worst hospitals he ever visited, " abominable, and a disgrace to Paris." He had frequently seen five or six in one bed, some of them dying. One shudders as one pictures to oneself the Hotel Dieu with 3655 patients thus packed together ! The jail-distemper then was not in Howard's time peculiar to the prisons of England or of the United Kingdom. It certainly did prevail in France, and pro- bably extensively ; for Murchison finds notices of it as occurring in the prisons of Nantes, Auxerre, and Rheims, also in Strasbourg and at Posen, in times comparativel}' recent. In place then of describing the jail -distemper as pecu- liar to English prisons, we must treat it henceforth as a disease prevailing in them to an unusual extent, and with extreme severity. And now I proceed to ask what this jail-distemper was : to inquire whether it was always one and the same disease, or whether there may not have been more than one fatal malady passing under the same name. The answer to these questions, as far as they relate to the jail-distemper of the last century, the disease with which Howard had to do, is very easy. It was evidently that Typhus Fever which our best authorities agree in attri- buting to crowds and overcrowding : to crowded prisons and workhouses, crowded hospitals, camps, barracks, and ships, crowded lodging-houses, crowded dwellings in town and country. Wherever men and children live for some time together in places small in proportion to their numbers. 1 84 Not always the same Disease. with neglect of cleanliness and ventilation, surrounded by oftensive effluvia, without proper exercise, and scantily- supplied with food, they incur the risk of this disease, and become centres of infection to others j and it is easy to understand how several persons having led such a life for weeks and months together, wearing the same clothing day and night, should come to be saturated with poison, and should be able to infect healthy persons breathing the same close and tainted air for hours together, as happened in courts of law at our successive Black Assizes. On the other hand, it is equally easy to under- stand how a single person issuing from such an atmosphere with such a taint upon him should be in a condition to infect crowds of persons living in a state not far, if at all, removed from that which had made him what he had come to be. Hence the infection of towns and villages, and of armies and fleets by recruits and pressed men fresh, from their sojourn in prison. But if we assume, as we safely may, that the jail-dis- temper of Howard's day was the typhus fever of our own j is it equally sure that our prisons always produced this infection and no other ? I think not. I deem it impro- bable that, in earlier as in later times, the many unwhole- some influences to which prisoners were exposed — want of air, water, food and exercise, cold and damp, and otFensive effluvia of every sort — blended, as they must have been, in every degree of intensity, in every possible com- bination and permutation — should have aKvays given rise to one contagious malady, and to one only. This reason- able expectation is fully justified by a careful comparison of the two Black Assizes of Oxford and Exeter — the one held in 1577, the other in 1586, and both described by Holinshed. At Oxford, there was sudden seizure on the spot of men only, no spread of the disease, bloody flux, and death within forty hours without delirium. At Exeter, Howard's Precursors. 185 110 immediate effect, seizure after a few days, " contagion and infection," spread of the disease through the county, and no mention of speedy death, or of bloody flux. The Oxford outbreak may have been a malignant dysentery j that at Exeter, the typhus of our day. I leave this curious question for more practical con- siderations, and for that eminently useful inquiry how did this jail-distemper — this prison-typhus of the eighteenth century — this physical expression of manifold prison neglect and mismanagement, cease and determine ? Who is to have the credit of that great reform which brought about the destruction of the destroyer r Hundreds of charitable per- sons, in every part of England, had taken pity on the poor debtor, and had given or bequeathed money for his relief, knowing full well how miserable he was 5 and every now and then, some rich man, or the King himself, would buy some wretched family out of bondage ; but no move- ment of reform came from them. There had been Black Assizes, with their terrible consequences ; and the law had been smitten, over and over again, in the persons of its highest dignitaries : but neither did the lawyers originate any reform. Medical charities had sent skilled physicians to the prisons on their errands of mercy j but they had rested satisfied with the work of palliation. The fever spread into our towns and villages, but neither local authority nor central government interfered to protect the lives of our people. It scourged our armies and fleets j but no word of remonstrance was spoken by Horse Guards or Admiralty. In 1701, the Society for Promoting Chris- tian Knowledge sent a committee to visit Newgate ; they distributed money and tracts, and exposed the gross abuses and immoralities practised there j but there, as in other prisons^ things went on as before. Again, in 1729, General Oglethorpe, and his Committee of the House of Commons, began a laborious incjuiry into the state of the Fleet, the i86 Biography of Howard. Marsbalsea, and the King's Bench, and the crimes and cruelties of the miscreants Bambridge and Acton. Reports were prepared and presented, these wretches were tried and acquitted, the horrors of these prison-houses were revealed to an indignant and disgusted public, their outraged feelings found expression in the verses of Thomson, and full justification in the lively pictures of Fielding, Smollett, and Goldsmith ; but still no reform. Even Oglethorpe, the benevolent and patriotic statesman^ the indefatigable chairman of Committee, the brave sol- dier, the wise administrator, linds no better course open to him than to gather some few debtors from the prisons, and with them and others in want of employment, to go forth and found the colony of Georgia. But the glorj' of reforming the whole system of imprisonment in England, missed by this kindred spirit and worthy forerunner, was reser^-ed for nearly half a centur)-, till, in a happy hour, John Howard was appointed sheriff of Bedford. In the year 1774, Howard was 48 years old. He had lost his second wife nine years before. He was a spare man of singularly abstemious habits, far from vigorous or robust ; and there was nothing in his then state of health, or in the histor)' of his ailing childhood and sickly youtli, to detract from the merit of his toilsome travels, and constant expo- sure to infection. He was neither learned nor accom- plished, hardly to be called well-educated 5 but he managed his estates wisely and liberally, and had always the command of money. His matrimonial arrangements and projects gave evidence of a strong will and some- what eccentric disposition. But he was quite as wise in these things as the judicious Hooker, or the devout John Wesley. It is easy to take exception to his management of his only child 5 and an ingenious psychologist might maintain the thesis that what was singularity in the father ripened into madness in the son. He was of active habit-i Sanitary Refoi'ins at Cai'dington. i'^^ and humane disposition 3 and as the one tempted him to travel, the other attracted him to scenes of distress. Thus, when he was thirty years old, in the year after the death of his first wife, he went to the scene of the great earth- quake at Lisbon. On his return he w^as captured by a French privateer, and had his first painful experience of prison life. And then it was that he had his first oppor- tunity of showing the sterling metal of which he was made : for, being Hberated on parole, he first made himself fully acquainted with the cruel treatment to Mhich English captives were being subjected in the prisons of France, and then, armed with facts, addressed himself to -the Commis- sioners of sick and wounded seamen, and not only "^ gained their attention and thanks," but the redress of the wrongs our sailors were enduring. Thus early did John Howard show his sympathy with suffering, his love of truth, his devo- tion to duty : thus early did he display his unconscious originality, his patience in collecting facts, his perseverance in using them, his rare unselfish singleness of purpose. The year of Howard's captivity in France (May T3th, 1756), the Royal Society did itself the honour of electing him one of its Fellows ; and he must needs justify their choice, by presenting three papers, the first on the degree of cold observed at Cardington in the winter of 1763, the second on the heat of the waters of Bath, the third on the heat of the ground on Mount Vesuvius. At Cardington, we are told, that on the first setting in of frost, he would leave his bed at two o'clock in the morn- ing, to note the state of the thermometer in his garden, at some distance from the house. In this simple trait of Howard the Philosopher, we see, by anticipation, the in- vincible perseverance, and abnegation of personal ease and comfort, of Howard the Philanthropist. And now I am to speak of Jolni Howard as Landlord. It was on his estate at Cardington, near Bedford, that. i88 High Sheriff of Bedford. 1773. Howard made his thermometrical observations in 1756. To that estate, enlarged by purchase of an adjoining farm, he brought his second wife, in 17583 there he continued to reside till 1774 5 and there he set an example to the landlords of England, by pulhng down and rebuilding every cottage that he owned or was able to purchase, erecting new ones j and, in a word, transforming the village from damp squalor to wholesome cheerfulness, from sickliness to healthiness, from barbarous neglect to civilized, judicious interference and supervision. Here, again, the work which duty prompted him to do, was done thoroughly and completely. It was, perhaps, our iirst considerable work of sanitary reform. The seventeen years that elapsed between the date of Howard's personal experience of prison life, followed by his successful intercession with the Commissioners of sick and wounded seamen, and the event that brought him again into direct contact with the prisoner, were spent mostly at Cardington, or at his house in Old Broad Street ; but he was absent now and then, as once (in 1767) when he gauged the temperature of the Bath waters, and once in Italy (in 1770), where he took the opportunity of ascer- taining the heat of the soil of Vesuvius. The event to which I refer, was the appointment of John Howard of Cardington to the office of High Sheriff of the County of Bedford. Xow it was the duty of a high sheriff to inspect the prisons and bridewells ; but this duty had been systematically neglected. But Howard was too careful a man not to ascertain what his duties were, and too conscientious not to perform them. And if any other motive were needed by such a man, there was his own bitter experience of his captivity in France, when he had been made to suffer the *' extremity of thirst," and the pangs of hunger, and had lain six nights together upon straw : and his recollection of the cruel treatment that Examination of English Pj'isons. 189 had caused " many hundreds of our prisoners of war to perish, and 36 of them to be buried in a hole at Dinan on one day." There was, also, by way of encourage- ment, the happy consciousness of the reform he had brought about by the simple, though toilsome process of collecting the facts of the case, and placing them, in all simplicity and earnestness, before those who had the power of redressing the wrong. Thus moved by that "fellow-feeling" which is apt to make men "wondrous kind," and encouraged by the memory of a great success, Howard was scarcely installed in office before he paid a visit to the prisons of the county town, beginning, as it is alleged, with the cell of John Bunyan. He found in the three prisons of Bedford, the county jail, the town jail, and the county bridewell, good illustrations of the then prevalent abuses, exaction of fees, and utter neglect of health. Of the first of these abuses, Howard says : — " The circumstance which excited me to activity in their behalf, was the seeing some who, by the verdict of juries, were declared not guilty ; some on whom the grand jury did not find such an appearance of guilt as subjected them to trial, and some whose prosecutors did ■ not appear against them, after having been confined for months, dragged back to gaol, and locked up again till they should pay sundry fees to the gaoler, the clerk of assize, &c." To the second of these abuses, Howard's attention seems to have been drawn after he had already visited most of the county jails in England. Having seen in two or three of them some poor creatures whose aspect was "singularly deplorable," and being told that they had been brought from the Iridewells, he set out on a new journey into the counties already visited, where he inspected, not only the bridewells, but the houses of cor- rection, and the city and town jails. In these inspec- 190 The Sanitary Act of L'j 'J ^. tions he displayed such industry and perseverance, that in the year following his appointment as High Sheriff, he had brought together a mass of materials in illustration of the two grand abuses to which I have referred, of such value tliat, when presented to the House of Commons, they not only gave him a public vote of thanks, but, what was to him infinitely more gratifying, they, with rare promptitude, passed two Acts — the one for the relief of prisoners who should be acquitted, respecting their fees ; the other for preserving the health of prisoners, and pre- venting the jail-distemper. This Sanitary Act has many of the properties of sound legislation. It is concise and clear, prescribes what is to be done, insures the requisite publicity, constitutes a body of inspectors (the Justices of the Peace in quarter sessions assembled), and provides a summary punishment for the infringement of its own provisions. But Howard, having reason to believe that the provisions of the Act were being imperfectly and negligently carried out, set out on fresh inspections of Enghsh prisons in 1776 and 1779, and published the results, with an account of some foreign prisons and hospitals, in 1777 and 1780. You will infer that Howard had excellent reasons for what he did when I tell you that, according to a calculation I have made, the prisons in which the law had been strictly obeyed bore to those in which it had been imperfectly carried into ertect the proportion of 15 to 130. Nevertheless, the good work was begun, and, gathering strength as time went on, the sanitary measures which the Act of 1774 had inaugurated, gradually drove out the jail-distemper, and at length made the prisons of England to rank among the healthiest of the abodes of men. And when I say this, I s])cak not only of our County and Borough jails, which approach somewhat in the character of their inmates (always excepting Howard* s Life, Deatk, and Character. \ 9 the poor debtors and pressed men) to the prisons of Howard's day, but emphatically of our great convict estab- lishments where the extremes of every crime, cruel, revolting, and fraudulent, fnid representatives by the thousand. I need not tell you that this great prison reform was wholly and solely due to the initiative of John Howard. I cannot tell you, for want of time, how much more he did for us in the seventeen years that elapsed between his appointment as Sheriff of Bedford, and his death in Russia j what voyages and journeys he made, what per- sonal experiences he gained in the prisons, hospitals, and lazarettos of Europe, what moral courage he displayed in his encounters with fever and plague, what physical courage in his fights with pirates in the Mediterranean and thieves in the Crimea. Nor can I describe his last crown- ing act of self-sacrifice, by which he caught the fever he had escaped so long 3 and '' died a martyr after living an apostle." Had time permitted, I should have wished to lay before you all the facts and incidents which supply the materials for a full estimate of his unique character. I should like to have defended it against his own modest depreciation of himself when he speaks of his work as ** a whim' and himself as a '^ plodder,'' as well as against the strange misconceptions of those who could see in this man of genius (for such Edmund Burke took him to be) " a dull, solid, dreary man," a " beautiful" and ''beatified philanthropist," a sentimental sort of being- possessed of *' a morbid sympathy with scoundrels."' This is the language of indignant reaction against the miserable self-indulgence and misplaced sympathies of the age in which we are living; but it is wholly and ludi- crously inapplicable to John Howard, who, if I read his character aright, had no sort of sympathy with crime or criminals, but a sense of justice, a submission to duty, a 392 Hozuard a Man of Genhis. moral and physical courage, an industry and perseverance, a truthfulness, simplicity, and modesty, which never before met in the same man, and probably will never meet again. He was emphatically one of those " English- men" to whom, if I may use the grand patriotic language of Milton, God, when he would work some great reformation, does, " as His manner is," first "reveal Himself." Once more I quote the words of Edmund Burke: " His plan was original, and it was as full of genius as it was of humanity. It was a voyage of dis- coveiy — a circumnavigation of Charity j" in a word, what I began this lecture by calling it, a Romance of History — a romance which shall to the end of time amuse and instruct, reprove and encourage, not those only who speak the language that Howard spoke, but those too, all the world over, who are able to appreciate the magnitude of the evils that he attacked, and the great- ness of the victory which he won. 193 LECTURE VIII. SMALL-POX. If I was right in calling my last lecture a Romance of History, I cannot be far wrong if I speak of this as the Romance of Science. For though Science has always been a wonder-worker, and often a dispenser of rare bene- fits to mankind, she never shone forth so brightly in both characters as when she put it into the mind of Edward Jenner to extract from the neglected gossip of the dairy the means of destroying the most loathsome and fatal pestilence that ever afflicted mankind. In so characterizing the small-pox I do not exaggerate. How loathsome it was, and what distressing consequences it entailed, in the shape of blindness, deafness, deformity, and impaired health, you all know. How it was the constant associate of the jail-fever in the prisons of England I have already told you. But I must vindicate by facts and figures its claim to rank as the most destructive of all our pesti- lences. We have already had under review, in former lectures, the Black Death, the Sweating Sickness, and the Plague ; the Scurvy, and the Jail-Distemper, Of these the sweating sickness may be set aside, as limited to England and a few nations of the Continent, and after five visita- tions during a short reign of some 66 years, ceasing from among us. Scurvy, too, from the very nature of its cause, and the jail-distemper, from its local character and partial o 1 94 Small-pox and Plague compared. prevalence, cannot be brought into comparison with the small-pox. The plague alone, by the frequency of its re- currence and the extent of its ravages, may claim to be put into competition with it as a destroyer of life. Let us examine this claim. I will first interrogate the London Bills of Mortality, and compare the deaths ascribed to small-pox and plague respectively in the years during which both diseases find a place in their columns. I am able to make this com- parison for the 7 years, 1630 to 16363 and the o^^) years, 1 647 to 1 679 : in all 40 years. These years comprise the plague epidemics of 1636 and 166^ 5 and yet while the total for plague is 87, 157, that for small-pox is no less than 34, 302. I cannot compare the deaths by plague and small-pox in any other group of years 5 but I may state that while the total mortality by the plague in 72 years, of which five were epidemic, was about 200,000, that by small-pox in 180 years did not fall far short of 300,000. The annual deaths from small-pox, witliin the limits of the London Bills, during the first 75 years of the eighteenth centur}', were largely in excess of 2000. Small-pox, then, since the time that we began to make a record of deaths here in London, down to the year 1820, has destroyed about three lives for every two that the plague destroyed in the 72 years that it was entered on the Bills of Mortality. If we had had a death-register for the whole of England during the same period we should, most probably, have found the deaths from small-pox much more numerous than those from plague. And if we could extend our inquiry to the Continent of Europe, and from that to the whole habitable globe, we might, perhaps, find reason to endorse the estimate of Sir Gilbert Blane, who thought himself " greatly within the truth in asserting tliat small-pox has destroyed a hundred for every one that has perished by the plague." Dr. Black's esti- Small-pox among Savages. \ 95 mate of the annual mortality from small-pox in Europe alone, in times preceding vaccination, reaches the high figure of 494,000. Among the reasons which may be assigned in favour of the superior mortality of smali-pox, I may mention its universal prevalence in every part of the world, among all races of men, among all ranks of society, in both sexes, at all ages, in all seasons 3 its habit of making itself at home everywhere, not content, like the plague, with occasional visits J the large proportion of the population whom it attacks, and the many among them whom it kills. I speak, of course, of the natural small-pox 3 and I do not hesitate to characterize it as the most frightful and de- structive pestilence that ever existed. To form a vivid idea of its horrors, we must see it at work among a tribe of savages, as many travellers and missionaries have done. Here is what Alexander Mackenzie says of the disease as it attacked the North American Indians. It was as a fire consuming the dry grass of the field. The infection spread with a rapidity which no flight could escape, and with a fatal effect which nothing could resist. " It destroyed with its pestilential breath whole families and tribes." After picturing the scene presented by the dead and dying, and the putrid carcases dragged out of the huts by the wolves, or mangled inside by the dogs feasting on the disfigured remains of their masters, he finishes by telling us that it was not "uur common for the father of a family, whom the infection had not reached, to call them around him, to represent the cruel sufferings and horrid fate of their relations from the influence of some evil spirit who was preparing to ex- tirpate their race, and to incite them to bafile death, with all its horrors, by their own poniards. At the same time if their hearts failed them in this necessary act, he was himself ready to perform the deed of mercy with his own o 2 19'^ No Respecter of Persons. hand, as the last act of his affection, and instantly to follow them to the common place of rest and refuge from human evil." To the same effect is the Rev. Mr. Cordiner's descrip- tion of the ravages of the small-pox in Ceylon, where, according to a very moderate calculation, it carried off a sixth of the inhabitants. We are told that the disease inspired the people with such terror that husbands forsook their wives, and parents their children, leaving them only a little drink and food ; that wild beasts attacked and destroyed the abandoned villages 3 and that not even the bones of the deserted sick were afterwards to be found. I will give you one more case of the same class. A Dutch ship, with small-pox on board, put into the Cape of Good Hope, and the captain sent the foul linen ashore to be washed. The small-pox broke out among the Hot- tentots who washed the clothes, and killed most of them. It then spread up the country to such an extent that the native tribes at last drew a cordon round the infected places, and shot all who tried to pass beyond it. This fact, cited from Dr. Mead, affords a good illustration of the liability of the disease to be conveyed in articles of clothing. That the small-pox was no respecter of persons appears from the fact that the father, mother, wife, uncle, and two cousins of our William \\\. died of it, and that the king himself suffered from it severely and permanently. Maitland, too, writing in 1772, alludes to " the havoc made in great families, not many months since, by that mighty disease, which seemed then to go forth like a destroying angel, subduing all before it." The origin of this destructive pestilence is involved in obscurity. It is said to have been mentioned in very ancient Chinese manuscripts, and in Brahmin records Its Early History. 197 '^'^66 years old. But the best authorities point to the fact that a disease so contagious had not been imported from Asia into Europe prior to the sixth century, as throwing dis- credit upon these statements. It is true that some lynx- eyed authors, such as Hahn, have thought that they recog- nised the small-pox in the writings of Greek and Latin physicians 3 but Anglada, ta whose able work on extinct maladies I refer you, proves, I think, that they were mis- taken. We do not touch solid ground in this inquiry till nearly three-fourths of the sixth century had run out. Small-pox certainly attacked the Arabian army at the siege of Mecca in 569, and soon after reached Alexandria. The Saracens carried it with them in their warlike expe- ditions, and by the eighth century all Europe is supposed to have became infected. But Anglada, quoting Marius, Bishop of Avenches, and Gregory of Tours, proves that as early as 570 the disease had shown itself in France and Italy. At what time it reached England w^e do not know. It was once thought to have been brought back to us by the Crusaders in the thirteenth century 5 but Woodville found that distinct mention of it had already been made, as existing both here and on the Continent, prior to the ninth century. But whatever the date of its arrival in England, small- pox, here as elsewhere, became a naturalized plague. We have notices of severe epidemics in 1174, 1365, 1440, 1556, 1564, and 1613 J and from 1629 to i83i,it is entered on the London Bills of Mortality in larger or smaller numbers ; in higher or lower ratios to the total deaths. In 1796 (the year of the introduction of vaccination) the deaths by small-pox exceeded 18 per cent, of the total ■deaths J and in 1772 they reached the high figure of 3992, or 15 per cent, of the deaths of that fatal year. Ihe returns for the eighteenth century show that the •mortality was subject to remarkable fluctuation. In 1702 198 Mortality. it was as low as 16, in 1796 as high as 184, per iooo ; and to this high ratio it rose from 50 the year previous, and fell to 30 the year after. If we call those years non-epidenaic in which the death-rate fell below 100 per thousand, and those epidemic in which it rose above it, we have 66 of the one to 34 of the other. So that we may say that small-pox was epidemic once in three years. And if we term those severe epidemic years in which the mortality exceeded 150 in the thousand, we shall have live such, or one year in 20 ; and all of these oc- curred in the last half of the centur)' ; the most severe of all within four years of its close. The years and ratios were as follows:— 1752, 173 J 1757, 1555 1772,1543 1781, 170 J 1796, 184. If we take tlie years of the century in groups of 20, the first group exhibits the lowest rate of mortality, the fourth the highest; the figures for the five being 68, 78, 87, 99, 93. I shall give you a fair idea of its relative mortality if I say that in the last ten years of the century it was more than a hundred times as fatal as diarrhoea and its allied diseases; six times as fatal as apoplexy, palsy, and sudden death taken together ; and seven times as fatal as the measles. So much for the prevalence of the disease, and the deaths it caused. Let us now inquire what was tlie rate of mortality among those it attacked, and what the proportion of the whole popu- lation whom, sooner or later, it destroyed. The deaths among those attacked by the disease may be taken, perhaps, at a fifth for all ages, and a third for adults. In what is called its confiuent form it killed a half; in \X.%discrete form about i in 25 ; in the intermediate degree, i in 12. But there have been instances of a mortality exceeding the highest ratio, and falling short of the lowest. In my first lecture I gave one instance of 2^ deaths in 44 seizures; and in my fifth I instanced a mortality of 13 in 19. The danger was always very In the Army. 199. great at the extremes of life — in infancy and old age. The death-rate among the mixed class of persons received into hospital in all stages of the disease was one in three. Of the mortality in middle life, we learn something from the experience of the army. Dr. Brocklesby tells us that about the middle of the century small-pox carried off about I in 4 of those whom it attacked in the natural way in encampments and winter quarters j and that only two out of nine soldiers escaped the disease. It follows, then, that out of 100 soldiers, only. 22 would escape attack, and the same number (22 in every loo, or 22 in 88 of all attacked) would die from this cause. The mortality in the navy would, in all probability, be higher still, so that we shall probably be within the mark if we assume that when the small-pox was not in any way modified or restrained by inoculation or vaccination, one- lifth of all the men enlisted in our army and navy died of this disease. I need not add that, as a constant associate of the jail-fever, it passed from our prisons direct to our armies and fleets. How often this happened may be inferred from a fact stated by Sir Gilbert Blane, that, in 1800, the small-pox broke out 20 times in our Channel fleet alone. The proportion of the whole population which small- pox destroyed may be inferred from the ratio which deaths by small-pox bore to those from all diseases in the eighteenth century. It was about i in 12. Jurin makes it I in 14 for the end of the seventeenth and beginning of the eighteenth century. Of the numbers out of the whole community whom sooner or later it attacked, we know nothing certain ; for while, on the one hand, we read that there was no age, however advanced, that the disease respected 5 on the other, we are told of whole families, or family groups,being small- 200 Mortality at different Ages. pox proof. Diemerbroeck mentions five octogenarians of his own family, and himself at 70, who had not had the disease j while Anglada, who quotes this fact, cites a fatal case at 70, and cases of recovery at 80 and 94 respectively; also a coincidence of an infant a day old, and a man of 80, at the same time under the care of the same physician. I may here state, in reference to its worst secondary con- sequence, blindness, that there is ground for believing that from a half to two-thirds of our blind population formerly owed their sad privation to small-pox. Some countenance is oriven to the higher estimates of mortality by a computation made by Dr. Haygarth that at Chester, in 1795, small-pox caused half the deaths of children under 10 years of age. From a table founded by Dr. Gregory on the Registrar- General's returns for 1837-38, I calculate the deaths at different ages as follows : — Out of 1000 deaths, 752 took place under 5 years of age; 171 from 5 to 15 ; 54 from 15 to 30; 21 from 30 to 70 ; and 2 after 70. These figures do not show the ratio of deaths to the living at the several ages ; but this is not needed for my present pur- pose, which is to illustrate the character of the disease by taking these facts into account in conjunction with what I have already stated respecting the occurrence of a small- pox epidemic every third year. If I read the figures aright, they point to a disease always specially greedy of the blood of children, but sometimes feasting upon them to repletion, and then waiting with cruel patience till the lapse of time had provided a fresh repast. Against this loathsome pestilence, so widely diffused, so unsparing, so fatal, so cruel ; blinding, deafening, and scarring many whom it spared, and sowing the seeds of future mischief in more; there arrayed themselves in course of time two champions — the one. Inoculation ; History of Inoculation. 201 the other, Vaccination ; the one introduced into England earJy in the eighteenth century ; the other towards its close. I shall first treat briefly of inoculation, then more at large of vaccination. The discovery and first use of the method of Inoculation is involved in obscurity. "^ Some poor unlearned, but Heaven-taught, mortal," as Kirkpatrick has it 3 some Chinese, Hindoo, or Circassian first hit upon it. Our own earliest information about it came from two Italian physicians, Pylarini and Timoni, referring to the early dates 1701 and 1713. Pylarini thought that it was first practised in Greece and Thessaly, and Timoni that it was introduced into Constantinople, by the Circassians and Georgians, about 1670. There is no doubt that it had been practised by the Brahmins of Hindostan from a very remote period, and that the Chinese have long " sown" the small-pox by inserting a crust into the nose. And, strange to say, a method of inoculation known as buying the small- pox had been practised in parts of Wales for at least a century before the introduction of inoculation from Turkey. Be this as it may, it was from Constantinople that inoculation came to us. About the year 1717, Lady Mary Wortley Montague, wife of the English Ambassador to the Turk, had her son, six years old, inoculated there ; and in April, 1722, her daughter, about the same age, here in England. This "charming and accomplished woman," in one of her playful letters, dated Adrianople, 17 17, thus justifies the step she was then contemplating. " Every year thousands undergo this operation, and the French ambassador pleasantly says, that they take the small-pox here by way of diversion, as they take waters in other countries. There is no example of any one having died of it, and you may believe I am well satisfied of the safety of this experiment, since I intend to try it on my dear little 202 Moj'tality from Inoadated Small-pox. son." Then followed, under the sanction of the Royal Society, six condemned criminals 5 next five pauper children of St. James's j then the children of a few families of distinction j and to crown all, their Majesties, acting on the cautious advice of Sir Hans Sloane, had all the Royal children submitted to the operation. Mr. Maitland, surgeon to the embassy, was the operator in these cases, and in some ten others in the same year. Naturally enough, though the success of the plan in commu- nicating a mild form of the disease was fully esta- blished by these early cases, the objection that the disease so imparted was the contagious small-pox, soon made itself felt. Indeed, Maitland himself had to deplore a ver}- convincing and sad proof that it was so j for having inoculated the child of a Mr. Batt, in Hertfordshire, six of his serv^ants, who had intercourse with the child, " were all seized at once with the natural disease, of which one died." The practice of inoculation, checked by this consideration, made its way very slowly j for Dr. Jurin, an industrious collector of facts, reports the total for 1722 to have been 182 3 and Kirkpatrick, adding together the cases brought together by Jurin and Scheuchzer for the first eight years after its introduction, obtains a total of only 897, of which 39 failed, and 17, at the ver}' outside, died. The rate of mortality incident to inoculation was cer- tainly very favourable when compared to that of the natural small-pox. This I will show by comparisons relating to the same time and place. The deaths follow- ing inoculation in 1722, and rightly or wrongly ascribed to it, were at the rate of i in 91, at the very time that Dr. Nettleton reported from many towns in Yorkshire a mortality from the natural small-pox of 19 out of 100, or ver}^ nearly i in 5. The first eight years of the practice yield an average of i in 50 at the outside, against a mor- Sue cess fid Inoctdators. 203 tality from the natural disease that certainly did not fall short of I in 5. I add a few facts relating to the early ])eriods : — In 172 1-2, while the small-pox in New Eng- land was killing more than a seventh of those whom it attacked, inoculation proved fatal to only i in 51. In South Carohna, in 1738, while i in 5 died of natural small-pox, only i in 100 fell victims to inoculation. Some inoculators, dealing with a few cases, were unfortunate. Thus, out of a batch of 25 inoculated at Dublin, there were 3 deaths, being the high ratio of nearly one-eighth. But this is quite exceptional ; and, as a set-off, I can cite from Kirkpatrick's work ratios after inoculation in Eng- land of I in 134, 186, 300, 370, 400, 425, 500, and 1000. But this is not all. Instances are cited by the same author of 134, 300, and even 1000 inoculated without a single death j and according to the statement quoted on the authority of Sir George Baker, at p. 17 of this work, the mortality might be reduced to something like i in 3000, x\s the numbers just given relate to persons of every age, and of mixed ages, to private persons, and children and adults in public institutions, the demonstration of the general safety and slight risk of inoculation may be taken to be complete. Without taking up your time longer with this part of my subject, I will state, as the result of my own reading and reflection, that while, soon after the introduction of the practice the mortality might be as high as I in ^o, it ultimately declined, as the result of growing experience, increasing care, and the progressive abandonment of the stifling system of treatment, to i in -;oo at the most, while the natural small-pox continued even to comparatively recent times to claim some such ratio of victims as i in 4, 5, or 6. The most successful inoculator (;[uoted by Kirkpatrick was a Serjeant Ranby. The Suttons also were noted for their success : but Dr. 204 Estimate of the value of Inocidation. Gregory gives much more credit to " diet and exposure to the open air." than to the antimonial and mercurial medicines which they extolled. Before I proceed to vaccination, I must examine a question full of interest in the last centur}^, and which has not yet lost its interest for us. I mean the real value of inoculation as a sanitary measure. If I have approxi- mated to the truth in the tigures submitted to you, we have, as it were, face to face, the natural small-pox with a mortality of, say, i in 5, and the inoculated disease with a mortality at the outset of i in 50, at length reduced to I in 500. So that if we suppose 1000 persons seized with the natural disease, something like 200 of them would die of it j but out of the same number submitted to inoculation, the deaths would not exceed 20 when the practice was in its infancy, and 2 when it had grown common, and prevailed largely. This saving of 180 lives in the 1000 on the least favourable supposition, and of 198 on the most favourable, will have to be set off against the deaths that may have taken place among the inocu- lated wdio, but for the operation, might never have caught the natural disease, added to the deatlis occurrinor amongr those who caught the infection from the inoculated, but who would not have taken it had the small-pox been left to itself. Hence we may infer that, if the natural small- pox spared only some small fraction of the population, inoculation could not have added largely to the infection and consequent mortality j but if, on the other hand, the natural disease did, sooner or later, attack only a moderate proportion of the entire population, inoculation might, in the long run, cause more deaths indirectly than it saved directly. Now I believe that the first supposition is the one which experience supports : I think that the small- pox did not spare any considerable fraction of the people ; but that, sooner or later, favourably or unfavourably, it Its effect on the Mortality by S^nall-pox. 205 infected the greater part of them. I should, therefore,, expect to find that a favourable. impression was made on the total mortality from small-pox by the introduction and spread of inoculation. Such, however, was not the opinion of Sir Gilbert Blane. He alleged that inocula- tion had been mischievous, inasmuch as the proportion borne by deaths from small-pox to the total mortality had increased during the last century from 78 to 94 per 1000 — figures which correspond very nearly to those I have already given. But Dr. Gregory, by dividing the last ninety years of the century into three periods of 29 each — 171 1 to 1740 (when there was no inoculation), 1741 to 1770 (when inoculation was coming into general use), and 177 1 to 1800 (when inoculation was almost univer- sal), obtained for the three periods the following deaths : — ^^^2>^?) j ^2>i?>'^^ '■) 57>2'58, or an ultimate saving of 81 15 lives ! Reasonable objection may, I think, be taken to this division, on the ground that inoculation was certainly practised to some extent long prior to the year 1741 j and also to the omission of a very necessary element in any such comparison — the number of the population. I shall steer clear of both these objections if I take the deaths by small-pox in three periods of ten years and compare them with the estimated population within the Bills of Mor- tality at or about the periods in question. I take, as fairly representing the mortality caused by small-pox, un- modified by inoculation, the decade ending 17 19; as corresponding to the introduction of inoculation into partial use, that ending 1749; and, as corresponding to the large and general practice of it, the ten years ending 17995 and these are the ratios reduced to the common standard of a million inhabitants : — First decade, 31,416 deaths 3 second, 28,282 5 third, 22,863. There is, therefore, a reduction in the last decade as compared with the first of 8553 deaths ; and sc far a confirmation of the thesis 2c6 Small-pox at the close of the i^th Century. maintained by Dr. Gregory against Sir Gilbert Blane. \i we take into account the salutary effect likely to have resulted from improved treatment and management of the sick, there will still probably remain some saving of life to place to the credit of inoculation. Before I pass from Inoculation the palliative, to Vac- cination the preventive, I must dwell for a short time on the small-pox as it showed itself in the last few years of the century when Jenner was busy with his great discovery. The disease then existed in two forms — natural small-pox, and small-pox modified by inoculation. What proportion the one bore to the other we do not know. But we learn from the London Bills that it was still a most destructive disease. Within their narrow limits it destroyed, in the last five years of the century, no less than 9827 lives 5 3548 in the first year of the series, 2409 in the last. We must go back 15 years to find so fatal a year as the first 3 and, with that exception, nearly as many to find a match for the last. That the disease still retained its epidemic character, the fall from 3548 deaths in 1796 to 522 the following year sufficiently attests 3 and that, when not modified by inoculation, it was as fatal as ever we have abundant evidence. So that medical men and the public at large must have had, at the time to which I refer, stringent reasons for desiring and welcoming some better means of dealing with small-pox than inoculation had pro- vided for them. They had had three quarters of a cen- tury of palliation with the evils always inherent in that mode of procedure ; they were now to have conferred on them the far greater boon of prevention with all its con- tingent advantages. The early history of vaccination belongs to the latter end of the i8th century, as that of inoculation did to the beginning of it. As the progress and development of Jenner's discovery belongs to the J 9th century, it does not Vaccination and Edward Joiner, 207 come within the scope of these lectures j and I shall refer to it, therefore, only as far as may be necessary to prove its value. The history of Vaccination is, to a degree quite unusual with great discoveries, that of the discoverer himself. I shall, therefore, treat Jenner in this lecture as I did Howard in my last. I shall blend the history of the dis- covery with the hfe of the man. These are the leading facts of Jenner's history. He was born May 17, 17493 the son of a clergyman. He was apprenticed, at the usual age, to a surgeon at Sodbury, near Bristol. On the expiration of his articles, he came to London to finish his studies, and lived in the house of the celebrated John Hunter two years, with my grandfather as fellow-pupil. He then established himself in practice in his native town — Berkeley, in Gloucestershire ; took the degree of M.D. at St. Andrews in 17925 made his first experiment in 17955 published the results of his experi- ments in 17985 received, in two Parliamentary grants, the sum of 30,000/., in 1802 and 18075 lived to see the triumph of vaccination, and died in 1823, 74 years of age. And now as to the discovery itself Jenner was born, apprenticed, and settled in practice in a county in which the cow-pox prevailed. It does not occur in all the coun- ties of England. Fortunately, during his apprenticeship, a young woman came into his master's surgery, and hap- pening to speak about small-pox and its dangers, said, ** I cannot take the disease, for I have had the cow-pox." This remark, coinciding as it did with the popular belief, made a strong impression on his mind. Other medical pupils and other medical men must have heard the same remark, and known of this popular belief 5 but Jenner alone stored it up as matter for thought and further inquiry. He spoke about it to John Hunter, and, on settling at Berkeley, often talked of it at his medical club, till his brethren 2o8 Character of Jenner^s Discovery. jocosely threatened to expel him as a bore. But Jenner was not to be deterred. He held to his opinions, and at length contrived to put them to the decisive test of experi- ment. If any one is inclined to think lightly of this tenacity and perseverance, or to suppose that any medical man with the same opportunities would have done the same, I would quote to him a case in point. Inoculation was introduced into England by Lady Montague, after her son had been inoculated by ]Mr. Maitland, surgeon to the embassy, in March, 17 17. Now that gentleman, by his own account, was fully convinced of the efficacy and safety of inoculation at that early date, and yet it is not till the summer of 1721 that we find him operating on the criminals in Newgate. Seeing that the experiments which Jenner had to make were already made for Mait- land in Constantinople, and that he was quite satisfied by them, he certainly showed a want of lively interest and alacrity which contrasts strongly with Jenner's earnest perseverance, though the censure which Dr. Robert Williams passes upon him is certainly exaggerated, and not wholly deser\^ed. Another consideration which en- hances the merit of Jenner arises out of the fact just stated, that inoculation had been practised in parts of Wales for a long term of years, and yet no medical man had o-iven serious attention to the immunity from small-pox which that local custom had notoriously conferred, jenner's merit, then, consisted mainly in the intelligence with which he received, and the perseverance with which he followed up, the information he had obtained from the milkers in Gloucestershire. His was not a great discover)', in the sense of requiring great original powers of mind, or great advantages of education ; it was great on account of the moral courage and undaunted perse- verance which carried it to a successful issue : and great What Vaccination is. 209 beyond all other discoveries of its class, or indeed of any- class, in the benefits conferred upon mankind. In a word, the discovery of vaccination is stamped by moral rather than by intellectual greatness, and this its moral character shines forth in every part of its history. For I need not tell you that in clinging to his first strong and just impressions, in bringing his convictions to the test of experiment, in promulgating and defending his discovery, he had to encounter grievous opposition, the compassionate incredulity of friends, the envious carping of rivals, the misrepresentations of enemies — nay, even the mistaken •objections of good and pious men — in a word, to undergo the martyrdom which seems to have been decreed as the lot of those who confer on the world the boon of great discoveries. It redounds to the credit of Jenner that he bore these severe trials well ; and that these an- noyances had as little power to irritate him as had his ultimate success to impair the native modesty and un- assuming worth of his character. Unspoiled by flattery, •unchanged by success, he continued to the last the same kind, affectionate, simple, truthful character he had ever been 5 constant in his attachment to natural history, active in the discharge of all his duties as a citizen, and unremitting in his atteniion to the pooi. Let us now examine this great discovery, and look for- ward as far into this, our nineteenth century, as may be necessary to test and determine its value. I assume that you know what vaccination is, that you understand it to be the introduction into the human body, by a puncture or punctures in the skin, of that same matter which forms on the udder and teats of the milch cow, and is transferred to the hands of the milkers j that its insertion gives rise only to local effects, with very slight constitutional disturbance 5 that it is not com- municable otherwise than by direct contact ; that F I o Success of Vaccination. it is a preventive of the natural small-pox, in the great majority of cases 5 and that when it does not prevent an attack, it mitigates its severity more certainly than a previous attack of small-pox itself does. It is interesting, though comparatively unimportant, to state that the local disease thus imparted to the human subject is but the small-pox itself, modified by passing through the body of the cow, and further that the same human malady becomes in the horse the horse-pox, or variolous grease. All this has been ascertained by experiments suggested by observation. Now vaccination, as we practise it, and as Jenner himself performed it, owes its origin to a series of simple infe- rences from the confident statement made to Jenner and others by the milkers — that having contracted cow-pox from the cow, they were thereby rendered proof against the natural small-pox — the first inference being that the infections matter would take effect as well when inserted by the point of a lancet as when rubbed into the skin of the hand 5 and the second that, if this insertion were followed by distinct local effects involving the production of lymph, that lymph would itself give rise to the same local consequences, and so on through an indefinite series of insertions. In a word, it was assumed, and happily demonstrated, that just as small-pox had been made to pass from person to person by the inoculation of the matter of a small-pox vesicle or pustule, so cow-pox might be communicated from person to person by the same mode of procedure. I will now apply to this preventive of small-pox that test of figures which I brought to bear on the palliative of inoculation. Vaccination, \\'hich may be said to have been introduced in 1796, could have had little eflect in limiting the deaths from small-pox in the remaining years of the century j for in Numerical Statements. 211 1 80 1 the total number of the vaccinated is beHeved not to have exceeded 6000. We must, therefore, allow a few years of the nineteenth century to elapse before we select a decade of years for comparison with the three which I chose as tests of inoculation in the eighteenth century. Let us take the ten years ending 1819, when vaccination had been brought into general use, and also the ten years, ending 1849, when ii^oculation may be said to have been superseded by vaccination. Well, the deaths by small- pox in London, which, in the ten years ending 1799 were 22,863 to the million of inhabitants, were reduced to 8045 ^"^ ^^^ million in the decade ending 18J9, and to 4798 in that ending i S49. So that, while inoculation could claim, at the outside, to have reduced the mortality from small-pox in eighty years by about 8500 deaths in somewhat less than 3 1,500, vaccina- tion might boast of having lowered the death-rate from nearly 23,000 to little more than 8000 in twenty years, and to considerably less than 5000 in 30 years more 5 or (to bring these figures together) from 22,863 in the decade that closed the eighteenth century, to 4798 in the short space of fifty years. But this is not all ^ for if I reduce my figures to the scale of one year instead of ten, still retaining the standard of one million of inhabitants, I am able to show a further decline of mortality coincident with a further extension of vaccination. Let me premise that, in the history of vaccination in the present century, there are three periods to be noted — one ending 1 840, prior to the enactment of any vaccination laws ; one ending 1853, during which vaccination was gratuitously provided J and one in which we are now living, that may be called the era of compulsory vaccination. Now, I will retain my own decades, with the understanding that the one ending 1849 fairly represents the gratuitous period, and add the decade ending with i860 as embracing seven years of 2 1 2 Extirpating Pouter of Vaccination. the period of compulsion. I take my last figures from Dr. Seaton's excellent Handbook of Vaccination. The figures for the eighteenth century which show the possible in- fluence of inoculation are .3141, 2828, and 22865 and for the nineteenth century, which display the effect of vaccina- tion, 805, 480, 272. A fall from 3141 per million per annum to 2286, represents, therefore, the reduction of mortality from the reign of small-pox uncontrolled, to the rule of small-pox modified by inoculation j and from 2286 to 272 the superiority of vaccination with State patronage and aid to inoculation without it. Or, if we employ a method of comparison I have so often resorted to in these Lectures, — I mean the ratio of deaths by small- pox to deaths from all causes — I find a progressive fall, with a single trifling interruption, from a maximum mor- tality by the natural small-pox of \ 08 in the thousand in the ten years ending 1770, to j 1 in the thousand in the ten years ending i860. I will place the figures before you for each decade. They are 108, 98, 87, 88, for the ioxxx decades of the eighteenth century ; 64, 42, 32, 23, 16,. 1 1, for the six decades of the nineteenth. These are remarkable figures ; but they are not such as would have satisfied the aspirations of Jenner, nor should they content us. We ought not to count our work done while any- thing remains to be accomplished. It was the cherished opinion of Jenner himself that vaccination is competent to the entire extinction, or, as we should now term it, stamping out, of tiie small-pox ; and this opinion of his was shown to be no idle dream by facts which came to his own knowledge. A manuscript of his, published by Baron in his " Life of Jenner," con- tains this striking history : " From the year 1762 to 1792, the number that died of small-pox in the Danish dominions amounted to 9728. About the year 1802, vaccination was first introduced, and the practice became general, but Past Sanitary Progress. 213 not universal \ however, 58 persons only died of the small- pox to the year 18 10. Vaccination, by command of the King, was now universally adopted, and small-pox inocu- lation prohibited, and from the year 18 10 to the year 1819, not a single case of small-pox has occurred.' Again, " From Bombay, I learn the small-pox is there completely subdued, not a single case having occurred for the last two years." These facts, amply confirmed as they are by others of the same order industriously brought together by Sir Gilbert Blane, are exactly such as we could wish to see gilding the sunset of Jenner's well- spent life, food for his joyful and pious reveries, warrants of the gratitude he felt towards God for the good he had made him the instrument of conveying to his fellow-creatures. If, when he was on the point of proclaiming the pre- ventive efficacy of vaccination, '' the situation in which he stood (to use the words of his biographer) has seldom had a parallel in the history of our race," what must have been his feelings, as, armed with such facts as these, he looked forward with confidence to the time when " this most loathsome and af^icting of all the scourges of humanity" would be banished, not from his own England only, but from the whole habitable world ? What else remains of this Romance of Science belongs to the nineteenth century, with which we are not at present concerned. And now I approach the end of these Lectures, and will take my stand for a few minutes at the point of time that separates the eighteenth from the nineteenth century, casting a glance back to the past, and forward to the future. The history of the remote past teaches us, I think, that whatever may be the case in warmer climates, it is true in these colder and temperate ones, that the nearer men are to nature the farther they are from health. In those days when the chief occupation of men was the care of ^14 Health and Civilization. cattle and the culture of a few fruits, and when manufac- turing industry was limited to the production of coarse clothing, frail and combustible habitations, and imple- ments for warfare and the chase, they were the prey of frequent famines and pestilences, and subject to a rate of mortality of which, in these days, we have happily no ex- perience. How much the contests of rival chiefs, the in- security of life and property, the condition of serfdom, the absence of roads, the huge unreclaimed tracts of forest and marsh, must hav^e weakened production and strengthened disease, it is not difficult to imagine. Passing on to the time when men began to collect in cities, and to fortify themselves by walls and moats against lawless violence, when the culture of grain took the place, to some extent, of the care of cattle, we still rind both town and country, the dwellings and the habits of the people^ hostile to health, favourable to the produc- tion of disease at home and the reception of pestilence from abroad. And even when we arrive at times that may claim to be •called civilized 3 when we had attained to a central and stable government, had long thrown otF the incubus of serfdom, had established flourishing manufactures and were carrying on an extensive commerce, had largely im- proved our agriculture, and taken our rirst lessons in horti- culture, our cities and houses were so squalid and rilthy that the plague found itself quite at home in them. Then, little by little, as civilization advanced, the twin virtues of cleanliness and temperance asserted their rights. Men bathed and washed oftener, submitted to frequent changes of linen, and admitted tea, cofl^ee, and chocolate into competition with beer, wine, and spirits. They came by degrees to live in better houses and cleaner towns. We saw the last of the plague, and were in the right way to rid ourselves of some, at least, of our home-bred pestilences. Sanitary Discoveries of the i^th Centzcry. 315 But I need not remind you how much remained to be accomplished, even as late as the last quarter of the eighteenth century. I have entered so fully into this sub- ject, and done, as I venture to think, such ample justice to it, that I must content myself now with reiterating what I said in my first lecture of the immense importance, in a hygienic point of view, of that remarkable epoch. One question, indeed, the sanitary triumphs of that epoch do suggest, for the answer to which we must look forward into the times of which men now living have had experience. Does the history of the last 70 years warrant us in looking forward to fresh sanitary discoveries and triumphs ; to a healthier, and therefore, happier future ? I answer this question, without hesitation, in the affirmative. These are the grounds of my confidence. In the first place, I am encouraged by the fact that Jenner's singular discovery has proved no idle dream of philosophy, but a great truth, fruitful in results, and in a fiiir way to realize the most sanguine expectations of its author. In the second place, I attach great importance to the fact that already this century can boast one capital hygienic discovery, — with which the name of Dr. Snow is so honour- ably connected — the discovery that cholera, to which we may confidently add typhoid fever, may pass from person to person, from house to house, from district to district, in drinking water. I recognise, too, as very important that other hygienic discovery due to the independent researches of Drs. Bowditch and Buchanan — that there is a decided relation of cause and effect between dampness of soil and consumption. These two truths must have a grand effect on the future of water-supply and drainage, on the cleansing of our towns, and the application of their refuse, solid and liquid, to our least fertile soils. In the third place, it is impossible not to feel the great importance which attaches to the happy results that have 2.i6 Gro2Lnds of Hope for the Future. followed in so many towns, on well devised measures of drainage and water supply. In the fourth place, I draw many inferences highly favour- able to our future progress in hygiene from the modern his- tory of medicine. We have made immense progress in the knowledge of minute structures, healthy and diseased, in the instruments by which we assist our senses, in our diagnosis and recognition of diseases, and in their treat- ment also. We have attained to a wonderful command over the function of sensation, as shown by our painless opera- tions and local anaesthetics. We have made, and are still making, immense progress towards what I may call the natural treatment of disease, as distinguished from those artificial procedures of w4iich I have given you some in- stances in these Lectures. We are far beyond the point at which 400 scorbutic patients could be sacrificed to a wild mercurial theory, or the lancet be ruthlessly employed to slay, not the fever, but the patient. In the fifth place, it is difficult to exaggerate the value of the mortuary returns now obtained from every part of the United Kingdom, or of the special inquiries set on foot by the medical officer of the Privy Council. And lastly, I augur well for the, future from the change slowly, but surely, coming over the public mind. It is being taught, in many ways, that the Policy of Palliation, in which we have so long indulged, is eminently unfruitful, and posi- tively mischievous. The time is evidently approaching when the Preventive Philanthropy (as I have ventured to call it) that guided the footsteps of Howard, will fill the hearts of the people, and the Policy of Prevention become the one rule of action of the Legislature. Should these Lectures be found to have helped forward, in some slight degree, the advent of this better time, I shall feel amply repaid for the labour I have bestowed upon them. THE END. ^^m^-m UNIVERSITY OF CALIFORNIA LIBRARY Los Angeles This book is DUE on the last date stamped below. NOV 2 9 1361 MAY 4 1362 MAY 1? ion NOV 2 5 1963 NOV 2 3 ^^^'^ MAY 1 3 1966 . idRECD •rm L9-25ni-9,'55 (B4283s4)444 \/A f i