". r ;i40 F794e 1876 TELEPHONE. UPLAND 26 DR. C. H. WIMPRESS OSTEOPATHIC PHYSICIAN VCRNON DRIVE r.ON OF STREET RAILWAY UPLAND, CAL. SKIN WITH FORMULAE. FOB STUDENTS AND PRACTITIONERS. BY TILBURY FOX, M.D., F.R.C.P., PHYSICIAN TO THE DEPARTMENT FOR SKIN DISEASES IN UNIVERSITY COLLEGE HOSPITAL, AUTHOR OF VARIOUS WORKS ON SKIN DISEASES, ETC. AND T. C. FOX, B.A. (CANTAB.), M.R.C.S. PHILADELPHIA: HENRY 0. LEA. 1876. PRtLADBLPHIA: r. HNS, PRIKTEK. ' TREATMENT OF SKIN DISKASI- Acne .......... 31 Alopecia or Baldness 33 Anthrax or Carbuncle 34 Area, tee Alopecia. Atrophia Cutis ........ 35 Bakers' Itch 36 Baldness, gee Alopecia. Barbadoes Leg, see Bucnemia. Boils, see Furunculi. Bricklayers' Itch 36 Bucnemia Tropica ........ 36 Bag-eruption 37 Cancer, see Epithelioma and Rodent Ulcer. Carbuncle, see Anthrax. Chlonsma, tee Tinea versicolor. Comedones 38 Condylomata . . . 38 Contagious Impetigo 38 Dysidrosis 40 Ecthynitt 41 Eczema .......... 42 Elephantiasis ......... 46 Epithelioma, or Epithelial Cancer 47 Erythema, or simple redness (hyperaemia) . . .47 Favus, see Tinea favosa. Fibroma .......... 49 Fish Skin Disease, see Ichthyosis. Follicular Hypersemia ....... 50 Fungi, see Tinea. Furunculus 50 Grocers' Itch 51 Gutta rosacea, see Acne rosaoea. Herpes *..... 52 Hydroa 53 Hydroadenitifl ........ 54 CONTENTS. Vll PAOF. Hyperidrosis . Ichthyosis ....... Impetigo ....... Intertrigo, see Erythema. Itch, see Scabies. . 54 . 55 . 56 Keloid . 56 Kerion, see Tinea kerion. Lepra ........ Leucoderma ....... . 57 . 57 Lichen ..... ... . 57 Lichen urticatus, see Urticaria. Lupus ...... . . Maculae ....... . 60 . 61 Medicinal rashes ...... . 62 Miliaria ........ . 62 Molluscum contagiosuin . Morphcea ....... Nails ........ . 63 . 63 . 64 Pediculi, see Phthiriasis. Pemphigus ....... Phthiriasis ....... . 66 . 67 Pityriasis ....... Porrigo . . . Prickly Heat, or Lichen Tropicus . Prurigo ....... Pruritus, or Itching .... Psoriasis ..... . 68 . 69 . 69 . 69 . 70 . 73 Purpura ........ Ringworm, see Tinea. Rodent ulcer ....... . 74 . 75 Roseola . . . . 75 76 Scabies or Itch ...... . 77 Scabies in Private Practice .... . 78 Scleroderma ....... . 81 Scrof'uloderma ...... . 81 Seborrhoea ....... . 82 Strophulus or Red Gum .... Sudamina ....... . 83 . 83 Sycosis ........ Syphilis of the Skin Tinea . 84 .85 . 91 Urticaria, or Nettlerash .... Vitiligoidea ....... Xanthelnsma . ...... . 96 . 98 . 98 Xanthelasmoidea ...... . 99 Xerodertna, see Ichthyosis. Zoster, see Herpes. viii CONTENTS. PART III. PAOF. CUTANEOUS PHARMACOPEIA 100 Baths 100 Fumigation 101 Caustics 101 Astringents . . . . '. . . . .102 Sedatives 103 Absorbent Powders ....... 107 Stimulants and Absorbents ...... 107 Posters Ill Mixtures Ill Pills 114 Remedies for Scabies and Phthiriasis . . . .115 Remedies for Vegetable Parasitic Diseases . . . 116 Diet in Skin Diseases . ... 118 EPITOME OF SKIN DISEASES. PART I. GENERAL OBSERVATIONS ON SKIN DISEASES. SECTION I. INDICATIONS FOR THE STUDY OP SKIN DISEASES. IN the successful clinical study and management of skin diseases, there are one or two important con- siderations which should never be lost sight of by the practitioner or the student. Firstly, as to the general character of skin erup- tions. There is nothing really special in their pathology. It has been a common remark that the study of skin diseases is bewildering on account, amongst other reasons, of the infinite variety of forms and aspects assumed by eruptions, and the multitudinous names given in consequence. Until lately there certainly was much truth in such a statement, but now researches in cutaneous patho- logy are fast clearing the path to a more correct knowledge of skin affections, whilst difficulties are rapidly vanishing, especial \y by the breaking down of those artificial distinctions which have so multi- 1 2 INDICATIONS FOR THE plied varieties and terms. It is now manifest that similar morbid processes go on in- the skin and in other parts of the bod 3% Indeed, da\- by day it is becoming more possible to group skin diseases according to their pathological affinities exactly on the same plan as other diseases. This fact in itself testifies abundantly to the clear insight already gained into the subject, and it also explains tin- circumstance that the student of to-day, who is compelled to acquire pathological knowledge in general, discovers that the stucty of skin diseases is rendered comparatively cas3' because of the analogy existing between the facts of general and skin patholog3 r . He does not find himself dealing with strange topics or data, but recognizes familial- appearances, changes, and causes, in morbid action. It is most important then to understand that there is nothing essentially special in cutaneous patho- logical changes as compared with those which occur in other parts. Secondly^ as to the mode of examining skin u:d pus formation or undue chronicity, and the like. The evil influences of such conditions must be thwarted, so as to pave the way for the proper ac- tion of curative measures directed against the dis- ease as a disease in the abstract. A few useful particulars or hints may be intro- duced here. Diseases of the skin are spread or take on an inflammatory character, or the changes in the skin are exaggerated, by exposure to all irritating agencies, heat, cold, scratching, the contact of acrid substances of all kinds, as by the handling of lime, sugar, soda, respectively by bricklayers, grocers, and washerwomen. So, too, an inflammatory aspect is given to eruptions by acridities in the blood, as in gouty or rheumatic subjects, in dyspeptics, and in those in whom the bile acids or retained ellV-to matters are present in undue amount in the blood. Eruptions in strumous subjects are attended In- more or less pus formation unusual to them under other conditions. Undue chronicity is occasioned oftentimes by the existence of nervous or general debility; for nature then lacks the natural recupr- rative power, and cannot exert it in aid of the cure. The questions of age, sex, occupation, mode of ELEMENTARY LESIONS. 7 life, and the general medical history of the patient, have to be considered, and will be incidentally re- ferred to in other places. Attention to the four indications already discussed will, however, be found of essential importance in the successful study or treatment of a skin disease. It may be observed, however, as regards age, that one essential difference between the cutaneous diseases of young life as compared with those occurring in the middle-aged and old, consists in the fact that the former are often the result of imperfect digestion and assimila- tion, whereas the latter are induced by mal-influences connected with the habits and occupations and wear and tear of adult life, and degeneration of structure in the old, and are modified by a number of func- tional and organic diseases of internal organs, which have not had time nor opportunity to develop in the vounsr. SECTION II. ELEMENTARY LESIONS. The elementary lesions are the types of form and aspect presented by skin eruptions. The student is required to know these at examinations, and a description of them will constitute a general outline of the pathology of the skin. They are nine in number, viz. : Maculae or stains ; redness or hyper- ffiinia ; w heals; papules; vesicles; bullre or blebs ; 8 ELEMENTARY LESIONS. pustules; squama; or scales ; and tubercles or large papules. Maculae, or Stains may be a. Pigmentary in nature when they are due to the presence of altered coloring matter of the blood. The stains may be secondary to other diseases e.g., syphilis ; or physiologi- cal e.g., pregnancy, or associated with certain cachexia; e.g., Addison's disease and leprosj*. The}' may be primary or idiopathic, and are generally left after hy- prrrcmia caused by irritants. b. Chemical, as in the case of stains from iodine, silver, bile acids, etc. c. Parasitic, due to the presence of fungus ele- ments e. g., tinea versicolor. d. Hffitnorrhagic e.g., purpura due to extra- vasated blood. Bedness or Hyper semia may be active (arterial) or passive (venous). Active hypera?mia consists of redness removable by pressure. It may be punc- tiform e.g., strophulus; or patchy e.g., roseola; it is often accompanied by swelling from effusion e. g., erythema papulatum; by disordered sensation (pruritis); by slight rise in temperature; it is often followed by desquamation, and occasionally exudation. It is caused by local irritants, by changes in the blood, and by excitation of the nerves. Wlieals are raised hyperannic swellings, that ELEMENTARY LESIONS. 9 have a palish centre, and rapidly form to as rapidly disappear. They are typically portrayed in the sting of the nettle. It is supposed that they are caused by sudden dilatation of a bunch of capillary vessels and escape of serosity. They are accom- panied by heat and great tingling. Some suppose the vessels beyond the point of dilatation are in a state of spasm. "Wheals are characteristic of urti- caria. Papules, or pimples, are little solid raised forma- tions in the skin. They maj" be due to hyperaemia of the papillae forming bright red points e. g., in strophulus ; or may consist of hypenemic, turges- ccut, and erected follicles e. g., lichen tropicus or prickly heat ; or due to deposit of lymph or the like about the walls of the follicles e. g., lichen planus; or are solid lymph formations or cell growths in the derma proper e.g., lichen, prurigo, syphilis ; or may be due to an epithelial collection in the follicles e.g., pityriasis pilaris ; or may be formed by hypertrophy of normal structure e. g., papillary warts. Vesicles are upliftings of the cuticle into minute bladders by fluid sweat or serosity; they are solitary or compound. Solitary vesicles may be due to sweat between the strata of the horny layer of the cuticle e. g., sudamina ; if larger (bnllse) by serosity between the horny and mucous layers of the cuticle e.g., pemphigus. All others are compound, and the fluid is collected in loculi 10 ELEMENTARY LESIONS. formed by the stretchecl-out cells of the ivle e. g., variola, herpes, erysipelas, blister, eczema. Further, in sudamina, blister, and pemphigus the fluid is sweat or serous; in variola, eczema, and herpes, exudation and pus cells in addition arc present in the rete, in the papillae, and the corium, which also gets thickened if the Inflammation becomes chronic. Bullae are simply large vesicles, and their struc- ture the same. In syphilis bulhe may occur, and then the contents become sanious, whilst ulceration is superadded. But usually the bullrc become tense with clear contents, then their contents get opalescent, the bullaj become flaccid and shrivel away, leaving only a red mark, without change in the cutis. Pnxtules are elevations of the surface by pus rapidly formed. They are accompanied by more inflammation than vesicles, and by a deeper a flec- tion of the tissues, but the loculi containing pus are similar in structure to those of vesicles. The pustules of ectlryma are large and deep seated, and possess painful indurated bases. Squamae or Scales are formed of detached epi- dermic scales. They differ from crusts, which are formed by dried discharge. Scaliness occurs as a secondary consequence in all inflammatory skin diseases ; squama?, particularly as an essential part of squamous inflammation e.y., psoriasis, pityri- asis rubra ; and in hypertrophic conditions. ELEMENTARY LESIONS. 11 Tuberculum is a solid fleshy lump in the skin, formed by the growth of new tissue. It is HOMOLO- GOUS e. g , fibroma, keloid, in which the connective tissue is involved; or HETEROLOGOUS e.g., cancer, lupus. There are certain " Secondary Changes" deserv- ing of notice. They are Crusting, in which crusts form by the drying up of discharge either poured free upon the surface through the inflamed derma e.g., eczema; or from ruptured bullae e.g., rupia; or discharged by an ulcerating surface. They may be due to sebum collected in masses, or to fungus elements e.g., favus. Crusts formed from the escape of serum are thin and bright coloured ; from dried pus, thick and }'ellow ; from dicing of bullfE, as a rule, thin and slightly dark ; from drying of sanious pus from ulcers, thick, dark coloured, and" heaped up ; from collected dried sebum, flat, easily de- tached, and greasy; in favus, pulverulent, honey- combed, and sulphur-yellow. Ulcer ation is usually the result of cachectic inflammation, such as the strumous or syphilitic ; or of new growths replacing the normal textures, and themselves softening and decaying, as in lupus and cancer; or it follows the softening of actual outgrowths from the skin, as in fibroma and j^aws. Excoriation is the exposure of the true skin without its removal, and is due to scratching or rubbing. Its seat is suggestive on the front of 12 CLASSIFICATION, OR DIAGNOSTIC the forearms and the thighs of scabies, and about. the clavicles and shoulders of phthiriasis. Scars are left I)}- traumatic injuries; caustics; and by certain diseases which ulcerate, such as variola, furunculus and anthrax, pustula maligna, strumous and s3-philitic disease. They signify that the true skin has been removed, and replaced by " cicatricial tissue." SECTIOX III. CLASSIFICATION, OR DIAGNOSTIC CHART OF SKIN DISEASES. The following list, or semi-chart, conveys a good general idea of the various eruptions met with in the skin, and regarded from a clinical point of view. The list comprises: 1. Eruptions occurring in connection with the acute specific or zymotic dis- eases, including the variolous rash, roseola vario- losa, vaccinia and roseola vaccinia, the rashes of typhus, typhoid, rubeola, rubeola nolha, scarlatina, glanders, and farcy, and dengue. These are impor- tant in reference to the differential diagnosis of skin diseases. 2. Eruptions, the local vumife&atiaM OF T>IA- TIIETIC STATES, comprising scrofulodermn, or scro- fulous inflammation; xyphilodermata, or syphilitic eruptions ; leproux eruptions ; framboesia or yaws ; CHART OF SKIN DISEASES. 13 eruptions occurring in connection with endemic cachexise, such as the Paranghi disease of Ceylon, etc. 3. Local inflammations, comprising : Erythemalous inflammation ; chief feature hyper- ffimia, with or without some slight consequent effu- sion of serosity. Erythema, intertrigo, roseola, urticaria. Catarrh a/, characterized by serous effusion into papillary layer, running on to sero-purulent dis- charge and crusting. Eczema, impetigo. Plastic, essentially papular, due to effusion of plastic lymph into the papillary layer, and sometimes the deeper dermic layer. Lichen, prurigo. Bullous, chief feature the development of bullae. Herpes, pemphigus, hydroa. Suppuratwe, essential lesion pustules, superficial and painless, or deeply seated and painful. Impetigo contagiosa, ecthyma, furunculus. Squamous, characterized by hyperaemia of the derma, and hyperplastic growth of cuticle. Pityriasis rubra, psoriasis. 4. Hypertrophic and atrophic diseases : A. Hypertrophic. Epithelial layers mainly affected. Pityriasis, warts, corns, xeroderma, and ich- thyosis. 2 14 CLASSIFICATION, OR DIAGNOSTIC Connective tissues of the skin specially involved. Keloid, fibroma, morphoea, sclerodermu. B. A trophic. Senile atrophy, linear atrophy, general mar.-i mus. 5. New formations, the characteristic being the growth of new tissue made up of granulation cells, or altered and proliferating connective tissue cells. Lupus, cancer, rodent ulcer. 6. Hsemorrhagic (cutaneous), effusion of blood, uninfluenced l>y pressure in points or patches. Purpura. 7. Neuroses, in which the nerves are primarily disordered, and there are no organic changes at the outset. Hyperresthesia, anaesthesia, pruritus. 8. Pigmentary alterations, consisting pri- marily of deposits or alteration of pigment. Pig- mentation, secondary to other diseases, is not in- cluded here. Melasma, leucopathia, xanthoderma, etc. 9. Parasitic diseases, comprising: A. Animal. Scabies, phthiriasis, eruptions due to gnat bites, fleas, etc. B. Vegetable. Tinea favosa, tinea tonsurans, tinea circinatn, tinea kerion, tinea versicolor, tinea sycosis, tinea decalvans, onychomycosis. CHART OF SKIN DISEASES. 15 10. Diseases of the glands and appendages, divisible into : A. Diseases of the sweat glands and follicles* as excessive secretion (hyperidrosis) ; dimin- ished secretion (anidrosis) ; altered secretion (chromidrosis, osmidrosis) ; congestive and inflammatory (miliaria, sudamina, lichen tro- picus, strophulus, dysidrosis, hydroadenitis) ; and sweat cysts. B. Diseases of the sebaceous glands, as excessive secretion (seborrhoea) ; diminished secretion (asteatodes) ; altered secretion, with or with- out retention (allosteatodes, xanthelasma) ; retention of secretion without inflammation (molluscum, horns) ; slight retention with in- flammation (acne). C. Diseases of the hair and hair follicles, as ex- cessive growth (hairy naevi, moles, hirsuties) ; diminished growth, constituting partial or absolute baldness (alopecia) ; textural altera- tion (fragilitas) ; inflammation of the follicles (sycosis). D. Diseases of the nails, including: changes occurring in syphilis, lichen ruber, general eczema, psoriasis, pityriasis rubra, and struma ; inflammation of the matrix, as in onyclua; parasitic disease termed onycho- mycosis, caused by the favus parasite or the trichophyton ; hypertrophy, atroph} 7 , and corn of the nail. 16 THE CAUSES OP SKIN DISEASES. There are then ten groups of skin diseases viz. : the eruptions of the Acute Specific Diseases ; Local Inflammations; Diathetic Diseases; Hyper- and A- trophic Disease ; New Formations ; Haemorrhagic, Neurotic, and Pigmentary Diseases ; Disorders of the Hair and Glands and their Appendages. Such is the clinical classification that may be given at an examination. Every skin disease must fall into one of these groups, and it soon becomes an easy matter to refer any disease before the observer to its pro- per class SECTION IV. THE CAUSES OF SKIN DISEASES. In the previous section a general summary has been given of the different varieties of skin diseases in the form of a tabular classification. In this section a sketch is furnished of the causes of those diseases, and they may be convenientl}' ranged under two heads : 1. Those which act from within the system upon the skin, or internal causes. 2. Those which act from without, or external causes. There are some who think that the latter are much more frequently in operation and much more potent than the former, but it is very doubtful it such is reallv the case. THE CAUSES OP SKIN DISEASES. 17 A. Internal Causes. Amongst these the most im- portant are: a. Hereditary tendency to a given disease, such as in the case of ichthyosis or psoriasis. It may give rise to a purely local affection, or to a more or less general disease i. e., one involving the skin locally and the general health as well. b. Blood poisoning, or impurification, by special animal or vegetable poisons, inducing specific eruptions, as in the acute specific diseases, sj'philis, or that derived from eating shellfish, etc.; by deficient excretion or the retention of excreta in undue pro- portion, biliary, renal, or intestinal in nature, giving to the blood an acrid character ; by long-continued dyspepsia, either from dietetic errors or otherwise ; by the presence of medicinal substances e. gr., potas- sium bromide, belladonna, or copaiba; by the accu- mulation of lactic or uric acids, as in rheumatism and gout, inducing eruptions and imparting an in- flammatory character to them ; by poverty which depraves the blood and leads to cachexia ; by the imperfect fulfilment by organs of their natural functions, as menstruation, perspiration, and hepatic and renal disturbance, c. Nerve disturbance, which acts in one of four ways. Firstly, by inducing changes in the calibre of the vessels by which the blood supply and fluid transudation is altered, as in the Erythemata. Secondly, lry directly encouraging tissue change, as in herpes and prurigo. Thirdly, by the loss of control over the skin nutrition, which follows from nervous debilit}', allowing morbid 2* 18 THE CAUSES OF SKIN DISEASES. action of all kinds in the skin to take place more readily. Fourthly, by the transmission of irritation through the reflex function by which eruptions may be excited or aggravated, d. An innate disposition in the skin tissues themselves to take on a diseased condition. This is a point on which special stress is laid. It is pretty certain that many diseases of the skin must originate in a disordered behavior of the very tissues themselves, and do not necessarily de- pend for their cause upon any general mal-nutrition. For instance, cancer is a case in point ; and so also warty growths of all kinds, fibroma, keloid, and even lupus, are other illustrations of the same thing. In some cases there is just an excess of growth, a plus state of the nutrition of the tissue and nothing more; or it may be a minus condition. In other instances it is a perverted nutrition, a deviation in the type of the tissue, as in cutaneous cancer. In fact, Group I V.. and many of the diseases in Group 10 of the clas- sification illustrate this point. It is asserted by most writers that such changes hypertrophy and atrophy are, in reality, merely the consequence of the presence in the blood of a greater or less amount of the pabula of the particular tissues affected. But if these pabula be in excess, which is unproved, the hypertrophy would not occur unless the tissues were disposed to make use of them fully, and, if such a disposition existed in a degree less than that of healthy nutrition, atrophy would result. So that, after all, the " formative capacity" of the tissues THE CAUSES OP SKIN DISEASES. 19 themselves is an important element in these plus and minus states of growth, and the explanation given above may be true, for if the tissues them- selves exhibit a tendency to hyperplasia, nature will answer the demand for an increased supply of pabulum. In the case of perverted nutrition (hcte- rologous formation) the changes are explained more readily by a perversion of the "formative capacity" than by altered character of growth, the conse- quence of a supply of a modified kind of pabulum. e. Climacteric or endemic influences induce skin disorder by depraving the nutrition of the body as a whole, as in Elephantiasis Arabum, Framboesia, etc. B. External Causes. Some of these influence the general health for evil, and so disorder the skin in- directly; others act directly upon the skin. 1. Amongst the external causes acting directly upon the skin, the most important are: Scratching, which may excite and always aggravates disease, and may, in contagious cases, spread it from place to place, as in scabies and contagious impetigo. Local irritants of all kinds ex., cold, heat, friction, flannel worn next to the skin, irritants, plasters, fluids, and applications of all kinds; irritating sub- stances, such as lime, sugar, flour, washing soda: pro- ducing bricklayers', bakers', grocers', and washer- women's itch ; unwholesome handicrafts ; dyes, con- tusions, animal and vegetable parasites of all kinds; medicinal applications, and want of care of the skin in the dirty and ill-fed. 20 THE CAUSES OP SKIN DISEASES. 2. Amongst the external causes that act indi- rectly upon the skin, through their influence upon the general health, ma}' be mentioned: Want of cleanliness, climatic influences, defective clothing, neglect, and the like ; animal poisons inoculated into the skin, etc. Clinically, it is of the highest moment to be ac- quainted with the fact that, as a rule, these scvrrid causes not only vary in character, but do not ope- rate in a solitary or individual way. To put it in another way : (1) these influences or agencies are, in reality, divisible into predisposing, exciting, pro- ducing, and intensifying causes ; and further (2) the true cause of the state of any given disease is made up of a number of phenomena or agencies iu combined operation. These are points of great practical importance in reference to the treatment of skin diseases. In reference to the first point, it ma} 7 be said that many so-called local causes only predispose, though the}- usually excite, to eruption. For in- stance, take the case of debilitating occupations, which render a man much more liable to be affected by the handling of irritants, or the influence of climate, by which the system generally is dis- ordered with the skin, and the latter so rendered liable to disease. Other causes act as pure \< i- tants, as when there is a predisposition to a disease e.g., eczema, and the local irritant excites it, but probably would not if acting without the existing THE CAUSES OP SKIN DISEASES. 21 predisposition. Some, however, are really pro- ducers of disease, as in the case of medical irritants or circulated poisons e. g., malignant pustule or parasites. Others again only aggravate existing disease, as in the case of the wearing of flannel, or exposure, or scratching. In reference to the second point, it is indisputable that, in most cases, several agencies or influences external or internal in origin or operation, combine to make up the true cause of a disease, and it is the duty of the physician to recognize the fact and analyze the cause correctly. In fact, in such correct analysis lies the source of all successful dennatological treatment. Diseases of the skin are very different things as portrayed on paper and in the consulting-room from a therapeutical point of view. A disease may answer most perfectly to the t} r pical description, but the remedies ordered for its cure may signally fail, because the analysis of cau- sation is incorrect or incomplete. For diseases are greatly modified as they occur in different subjects, and it is not the uncomplicated type that is to be dealt with in practice, but the disease modified and influenced by the many concomitant conditions of age, constitution, occupation, etc. It may be useful to mention a few common com- binations met with clinically, which illustrate the multiform character of the causation of skin diseases, as seen in the consulting-room. In the case of eruptions provoked by local irritants, re- 22 THE CAUSES OP SKIN DISEASES. ferred to above, there is very frequently debility present which favors the development of the disease. and which must be got rid of if the eruption is to get well, and if it is to be cured, in the best way. lu fact, the skin of a healthy person will mostly resist the action of many of the local irritants specified, but cannot do so if the subject be weak and debilitated ; so that it is an important point to give tonics, as the rule, in cases of eruptions excited by local irritants. Here there is one simple com- bination of causes, debility and local irritants, in- ducing erythema, eczema, lichen, etc. Other ex- amples readily occur, such as eczema in a gouty subject, modified by neglect and scratching; pso- riasis in a strumous subject in whom the tendency to the disease is hereditary ; erythema in a rheuma- tic subject, in connection with dyspepsia ; eczema occurring in cooks exposed to the irritating in- fluence of the fire, whilst the patient also has a blood current charged with retained excreta, in consequence of inefficient bowel and kidney action ; lupus in a scrofulous subject ; tinea tonsurans in a boy with persistent anaemia and a phthisical ten- dency; pruritus in connection with senile atrophy of the skin, liver derangement, and gout. Other examples might be multiplied almost indefinitely. In estimating, therefore, the cause of an}- given cutaneous disease, attention must be paid not only to predisposing and exciting causes, but to coin- cident occurrences and accidental concomitants DIAGNOSIS. 23 modifying such disorder ; for it is not in the ab- stract that the disease is to be regarded, but in its entirety, and in all its clinical features and be- haviors. The correct estimation of a disease after this fashion comprises the diagnosis, upon which a few remarks will be made in the next section. SECTION V. DIAGNOSIS. Firstly. In making a diagnosis the observer should apply the rule laid down (Section I.) for examining skin diseases viz., to scrutinize the whole of the eruption, not a part only, and trace carefully its history to discover the nature of its beginning, the character of its stages, if any, and their transitional relationship, and the general course of the eruption up to the time of observa- tion. Secondly. The observer must proceed to determine to which class the disease belongs, according to the principles laid down in the chart in Section III. Is it an eruption of the Acute Specific Diseases? Then the constitutional con- dition will be by far the most pronounced, the patient more or less prostrated, the temperature unusually high, whilst the other pyrexial symptoms will be marked and out of proportion to the mere rash; the access of the malady will have been comparatively sudden, and so on. Is the eruption 24 DIAGNOSIS. essentiall}' ery thematous ? It must be one of four conditions viz., erythema, intertrigo, roseola, urti- caria ; and the reader is referred for the features of these to the special description in Part II. Is the disorder accompanied by sero-purulent discharge, by the development of bullae, by pustules, or by squamae alone ? Then the disease is one of those comprised under local inflammations. Is the erup- tion part of a cachexia, or some special diathetic condition present? Then it belongs to Group II. And in a similar way may Hypertrophies or Out- growths of Tissue, Atrophies, New Formations, Hemorrhagic Spots, Neurotic conditions without organic changes, Pigmentai^y alterations, Parasitic diseases, and affections of the Glands, Hair, and Nails, be put under their respective headings. In the case of New Formations, the diagnosis is singu- larly easy. The j-oungest student can readily distinguish the newly-formed fleshy mass of a neoplasm in the skin from the ordinary rapidly formed semi-hyperaemic inflammatory deposit of a similar size; and he knows practically that he has a case of syphiloderma or lupus to deal with. In making a dianosis, the observer must remember to determine whether the disease is or is not com- plicated by another, as evidenced by a mixture of characters, and to thoroughly sift out the nature of any constitutional modifying influences. T/i irdly. An estimate of the immediate or exciting cause of any given eruption is of the first importance in a TREATMENT. 25 complete diagnosis. No doubt, when the observer has been able to put the disease before him into its proper class, a pretty correct indication is obtained of its causes, especially as regards Classes 1, 2, 4, 5, 6, 9 (Section III.); yet, unfortunately, the difficulty is greater with the eruptions of the commonest occurrence, comprised in Class 3, and with those in Classes 7 and 10 (B and C). Hence the observer must proceed on the lines laid down in Section IV., working out the specific cause, and inquiring into the production of the eruption from within or without. Is the cause an hereditary tendenc}-, the result of blood poisoning, nerve disturbance, a disposition in the tissues themselves to take on a diseased condition, or climatic influ- ence ? Is the cause to be sought in local agencies, as detailed under B (Section IV.) ? And at the same time the observer will bear in mind what has been said about the multiple character of the causes of skin diseases. So the diagnosis will be correctly worked out. The way is now prepared for some remarks on the therapeutics in the following sec- tion. SECTION VI. TREATMENT (GENERAL PRINCIPLES). If, as has been already stated, there is nothing essentially special in the pathological changes that occur in skin diseases, it follows that there can be 3 26 TREATMENT. little that is absolutely special in the treatment. What differences there are arise from the fact that the skin can be irritated directly, and that the diseased parts become rapidly dry. harsh, cracked, etc., from the constant exposure to the air, so that they need to be kept protected and supple by the use of moistening applications. Otherwise the general principles of therapeutics arc applicable to the case of skin maladies, and it is necessary for the reader to mentally lay linn hold of this fart. A correct diagnosis must precede successful treatment. When in accordance with the rules laid down a given disease has been placed in its proper clinical class, and the exciting and other causes discovered, the proper kind of treatment naturally suggests itself. It may be said, indeed, that the ten groups of skin diseases require three main methods of treatment viz., a purely local one, or one almost wholly general, or a mixed kind, partly local and partly general. That is, indeed, saying in other words that skin diseases are made up of those essentially local in nature, those essen- tially general, and those more or less local in their main features, but influenced by general conditions. In the first category may be placed Groups 4, 5, and 9; in the second Groups 1 and 2; and in the third Groups 3, 6, 7, 8, and 10. In dealing with the local mischief in Groups 4 and 5, absorbent or astringent remedies to promote resolution or removal by caustic or surgical means, TREATMENT. 27 constitute the treatment. In Group 9 parasiticides are to be employed to kill the insect or fungus which produces the particular disease present. In dealing with the components of Group 2 for I need not touch on Group 1 specific remedies are used : in scrofuloderma, cod-liver oil ; in syphilis, mercury ; in leprosy and frambo3sia, hygienic meas- ures and so-called " specifics." So far all is clear. When we come to the third or mixed class of cases indicated above, the principles of treatment are more varied. Groups 6, 7, 8, and most of the diseases comprised in 10, are consequent on what may be conveniently termed debility, and the treatment consists of the use of general tonics, etc. It is not necessary to add more about them, as they are amongst the more infrequent of skin maladies. As regards, however, Group 3, the case is different, for the diseases comprised in it con- tain, as will be seen at a glance, almost all the ordinary forms of skin diseases, and it is amongst these the greatest difficulties are met with, owing to the many causes of excitation, aggravation, and modification. Now the diseases comprised in this group are essentially inflammatory ; some run a course of definite duration, as in herpes and roseola, and hence require on\y watching to prevent inter- currcnces, or for the alleviation of special symp- toms and conditions, such as pain or disfigurement. The majority, however, run an indefinite course, and are to be attacked by therapeutic measures, 28 TREATMENT. based upon a consideration of the varying com- bination of exciting, aggravating, or modifying agencies. The treatment must be by local and internal remedies. As regards local remedies, there are three main rules to be observed, viz.: (I) whenever active hy- penemia is present, be the disease what it may, ap- plications of a stimulating nature should not be used, but the treatment should be essentially SOO/////K/, otherwise the inflammatory S3*mptonis will be in- cn-ased, and the disease spread. (2) The action upon the skin of an external irri- tant as scratching should IK? prevented, and the air excluded from inflamed or excoriated surfari-s. especial!}- by oil-packing and otherwise. (3) Not until the stage of active byperaemia has passed should astringents, stimulating applications. or revulsives be employed. These, and absorbents, are to be reserved for the stages of vascular slug- gishness and inflammatory induration and thicken- ing- As regards internal or general remedies, it is pro- posed to indicate below, in as practical and concise a form as possible, the conditions which should be taken into consideration in -framing the treatment of such diseases as erythema, intertrigo, urticaria, eczema, lichen, prurigo, pemphigus, hydroa, ecthy ma, furunculus, pityriasis rubra, and psoriasis; and in- flammatory conditions of the glands and hair folli- cles, as acne, dysidrosis. and sycosis, which are ana- TREATMENT. 29 logons to, and only differ in regard to their anatomi- cal seat from, those preceding. This short sketch or chart, inasmuch as it applies to the bulk of skin diseases, should be used regularly in determining the treatment, which must necessarily vary with the different combinations of influencing agencies re- ferred to. These conditions are: A Syphilitic Taint which tends to induce indu- ration from the presence of syphilitic tissue ; or ul- ceration, cachexia, and general debility in eczema, psoriasis, pemphigus, ecthyma, acne, and intertrigo, (infants). , Constipation which causes dyspepsia, liver torpor and retention of excreta, and occurs in all forms of skin diseases. Debility, including anaemia, which retards re- covery from want of recuperative power in the system, all functions sharing in the debility. It is especially operative in furunculus, eczema, pity- riasis ruhra, pemphigus, and ecthyma. Diabetes which increases an}' inflammatory con- dition, favors phlegmonous inflammation, and leads to freer development of disease, and to chronicity. Its influence is often seen in eczema, psoriasis, in- tertrigo in adults, furunculus, and anthrax. Dyspepsia which induces debility, leads to liver disturbance, impurifies the blood, and increases hypenemia by reflex action, as in acne, eczema, urticaria, and sycosis. Errors of Diet which introduce special irritative 3* 30 TREATMENT. substances into blood, cause dyspepsia, lead to accumulation of nitrogenous matters in system, to liver disorder, etc., and complicate all forms of inflammatory eruptions without exception. Gouty and Rheumatic Diatheses which cause accumulation of uric and lactic acids and allied compounds in blood, and give an inflammatory character to disease, as seen in eczema, psoriasis, lichen, ecthyma, sycosis, and urticaria. Lack of Hygiene which disposes to torpor of skin, and favors the occurrence of morbid action and disease, as seen in acne and sycosis, eczema, intertrigo, and erythema especially. Repression of the special normal el i minatory functions (skin and menstrual), which throws the necessity of compensatory elimination on the skin, which may fail to respond, and so become diseased. In dependent parts this leads to increase of fluid in tissues. It occurs in furunculus, ecthyma, and eczema. Retention of Excrela, from kidney, liver, and bowel inactivity, which gives the blood an irritative quality and aggravates hypenemia in all inflam- matory skin diseases. It also leads, in the case of kidney torpor, to increase of watery fluid in tis- sues, as in eczema of the legs. Simmons Diathesis which imparts an unusual purulent character to eruptions, and favors the implication of the connective tissues, as in eczema, Psoriasis, acne, and sycosis. PAET II. THE DESCRIPTION" AND TREATMENT OF SKIN" DISEASES. Acne is an inflammation of the sebaceous glands, the ducts of the glands, and the upper part of the hair follicles. Mostly resulting from the retention of the sebum (comedo), it attacks chiefly the face and shoulders, and occurs especially about the time of puberty, when the hair follicles are in a state of physiological activity in connection with the free formation of hair, and are in consequence easily disposed to become the seat of disorder. The varieties are four in number viz., acne punctata, in which there is simple retention of dis- colored sebum, called comedo, without any inflam- mation, but a certain amount of prominence form- ing a pimple ; acne simplex, in which slight perifol- Hcular inflammation and occasionally suppuration are added to the retention of sebum ; acne indurata, which is marked by considerable inflammatory induration at the base of the spots, and a certain degree of suppuration ; and lastly, acne rosacea, characterized by a bright red color, more or less formation of new connective tissue about, and hypertrophy of the glands, and by its occurrence 32 THE DESCRIPTION AND iii middle-aged persons oftentimes the subjrfN >r menstrual disorder. The hyperamiia present in acne is especially intensified by dyspepsia, errors of diet, and local irritants. The inflammation, too, is modified by the strumous and syphilitic cachexiae, which conduce to implication of the surrounding cellular tissue and to suppuration in struma, and to induration and ulceration in syphilis. The condition denomi- nated acne rosacca is scarcely a true acne, but con- sists of chronic h\ peraemia of the face, attended by the formation of red papules, due to the effusion of lymph into the papillary layer of the skin. These papules show out from the general reddened surface as minute elevations like non-suppurating acne spots, but they present no central opening. The occasional presence of true acne spots leads to-the inference that the disease is really acne. Treatment. The objects in view are firstly, to get rid of concomitant aggravating conditions (see above); secondly, to remove the plugs of sebum from the follicle (in comedo especially) and to lessen the IrypenxMiiia ; thirdly, to restore tone to the vessels and to the general system ; &nd fourthly, to promote the absorption of inflammatory products. In applying these principles, in acne punctata, hot water bathing with friction with mild soap and the use of an alkaline wash (45), or if this fail (07), cautiously used, and tonics, constitute the proper treatment as the rule (see Comedo). In acne TREATMENT OF SKIN DISEASES. 33 simplex it is necessary to remove the dyspepsia, if present, by (97) before giving tonics such as (90), (107), or (108), or in anaemic subjects (94). Cod- liver oil must be prescribed for the strumous. Locally the affected parts should be bathed with hot water twice a day, and soothed with (14) or (74) to reduce the hyperaemia, and presently stimu- lated with (64) or (66) diluted. In acne indurata similar internal remedies are required at first ; or if the system be loaded (96) or (98) ; if much indu- ration (85). Locally soothe as in acne simplex, and subsequently remove the induration by the use of (47), (60), or (66); or, if necessary, occa- sionally touch each spot with acid nitrate of mercury. In acne rosacea it is necessary to look to the state of the uterine functions, to remedy coexisting dyspepsia, debility, tippling habits, etc. Internally (95) may be given with advantage; locally (74) may be used, with the occasional application of acid nitrate of mercury to each spot, or (80) may be applied each night. In some cases it is advisable to cut the vessels across with a lancet, and to apply, after the parts have bled, collodion regularly for awhile. In indolent cases of extensive acne rosacea and indurata (65) may be used every night or every other night. Alopecia or Baldness may be partial or gene- ral, hereditary or acquired, idiopathic or symp- tomatic. When symptomatic, the baldness is usually a relative one, and it results from the clis- 34 THE DESCRIPTION AND torbanee of the nutrition of the part by inflammatory diseases e.gr., eczema; or by blood diseases e.g., syphilis ; or by parasites (see Tinea) ; or from de- bilit}^ from other special causes. When idiopathic, it results from atrophy of the affected parts, and failure in the reformation of hair, and then is abso- lute, usually taking the form of circumscribed areas (areata or circumscripla), which gradually extend ; the skin itself is white, less vascular, and less sensi- tive than usual. Treatment. In symptomatic cases the treatment of the alopecia is that of the disease which induces it. In the idiopathic forms, where the entire hair is lost, little can be done save by continuous stimu- lation. When more localized, however, good may be effected by applying tincture of iodine daily for two or three weeks, or rubbing in an ointment com- posed of two grains of bichloride of hydrargyrum to one ounce of lard for a fortnight or so, and especially round the edges of the bald patches; then, or when minute downy hairs appear (129), or better (130), ma}' be infricted with perseverance. At the same time appropriate tonics are to be prescribed should there be anosmia or debility. Anthrax or Carbuncle is a phlegmonous in- flammation of the skin, with necrosis of the cellular tissue and indolent suppuration, the necrosed tissue forming man}- cores over the surface of the car- buncle, and being discharged, together with pus, through the several corresponding apertures. The TREATMENT OF SKIN DISEASES. 85 surrounding parts are brawiry, reddened, and indu- rated, and the vessels plugged. Carbuncles are painful, and exhaust by their irritation and accom- panying discharge. Extensive sloughing and ul- ceration may occur, and even P3 r femic sj-mptoms. Their most common seat is on the back or back of the neck, and they may occur singly or one or two together. The subject of them is usually much de- pressed in health, and often of a diabetic habit. Treatment consists in the application, in the early stage, of caustic potash, or the employment of a subcutaneous or other free crucial incision, with subsequent pressure and careful dressing. Inter- nally, the greatest attention should be paid to sus- taining the strength of the patient, by food, medi- cines, or stimulants,, as the case may require. Area, see Alopecia. Atrophia Cutis may be localized, and is then mostly secondary to the growth and disappearance of neoplasmata, strumous and syphilitic ulceration or degeneration of the skin, as in morphoea ; local inflammatory action, as in the scars left b}' ecthyma, zoster, and variola ; and traumatic lesions. It may be more or less general, and then is a part usually of general senile decaj r ; or congenital, as in some rare cases of xeroderma. The atrophy may be idiopathiC) and then usually takes on the linear form, and is localized to certain parts of the body, and results probably from some defect of innerva- tion. 36 THE DESCRIPTION AND Treatment. In the idiopathic form, all that can be done is to afford protection to the part locally. and to give appropriate general tonics internally. Bakers' Itch is a term which includes lichen agrius and chronic eczema of the hands. It is in- duced by the irritant action of the flour used by bakers (nee Eczema). Treatment Patients are often considerably out of health, and have a loaded system, though they are debilitated. For such (95), or even (96), are to be given, and these may be followed up by tonics, such as (94) or (108). Locally the part may lie- first soothed by (76), or the linimentum calcis, or, if very itchy, by (40) or (42), and afterwards, when the inflammation is subdued, (69) or (78) may be employed. Baldness, see Alopecia. Barbadoes Leg, see Bucnemia. Bricklayers' Itch is similar to bakers' itch, only that it is excited by the irritation of lime. It requires similar treatment to bakers' itch. Boils, see Furuniculi. Bucnemia Tropica is an hyperplasia of the connective tissues, generally of the lower limb, suc- ceeding to repeated attacks of inflammation of the lymphatics of the limb. As a consequence of the lymphatic obstruction, a greater quantity of lymph is retained in the connective tissue strata of the skin. The disease may attack the scrotum (then called Sarcocele) and penis, as well as the limb, and these separately or at the same time. In some TREATMENT OP SKIN DISEASES. 37 cases, the lymphatics are varicose. The cause of the lymphatic inflammation in ordinary elephanti- asis is probably due to residence in damp humid localities, especially such as are tropical or malari- ous. But Chyluria may coexist with the disease, and chyle-like fluid may exude from varicose lym- phatics in the enlarged scrotum ; and as chyluria and chyloderma are associated with the presence of filariae in the lymphatics, it has been asserted by some, that the form of scrotal disease in which chyle-like fluid is formed is only a phase of ordi- nary elephantiasis of the scrotum, and that in ele- phantiasis of the leg or scrotum or other part, the true cause of the lymphatic inflammation is the irritation and obstruction caused by filariae ; but it has not as yet been proved that such is the case. Treatment. In the earliest stages, it is that of inflammation of the lymphatics : in the chronic state friction, continuous bandaging, mercurial inunction, and finally ligature of the main artery of the limb, or excision of the part, if the disease is localized in the scrotum, have benefited. Bug-eruption. The attacks of bugs is a com- mon cause of skin irritation in children, leading to pruritus and urticaria, conditions which are intensi- fied or appear at night. The bug-bites may often be detected as rosy papules with a central punctum. The remedy is to 'get rid of the bugs from the rooms or beds, whilst the pruritus they induce maj r be relieved by alkaline baths (14), (23), (43). 4 38 TIIE DESCRIPTION AND Cancer, see Epithclioma and Rodent Ulcer. Carbuncle, see Anthrax. Chloasma, see. Tinea versicolor. Comedones are the small black-topped seba- ceous plugs, or accumulations of sebum, that are found in the early stage of acne punctata. The form of disease in which these occur is called Co- medo. Treatment consists in the free use of hot water, and if the skin is irritable, in applying borax or alkaline washes (19), (45), and subsequently when the skin is less irritable, in using tar soap, or soft- soap inunction cautiously, to be followed by (14), to allay irritation, and finally to stimulate the glands to healthy action by such as (B5), (67), or Condylomata or "mucous tubercles" are small tumors, generally sessile, with a circular outline and somewhat flattened top, occurring as a part of syphilis. They are usually reddish or brownish in color and spring up on mucous or cutaneous or more often on muco-cutaneous surfaces. They are contagious and liable to suppurate, and contain the peculiar syphilitic tissue in their bases. The treat- ment locally is to keep them constantly clean and dry, and to apply astringents ; or such mercurial preparations as blue ointment, calomel powder, or a lotion of bichloride of mercury (gr. i-ij to 5j of water). Contagious Impetigo is a disease quite dis- TREATMENT OF SKIN DISEASES. 39 tinct from pustular eczema. Sometimes it is quasi- epidemic, but mostly sporadic. It attacks children only as a rule. The eruption occurs chiefly about the face and head and more uncommonly the hands and body. It may be ushered in by slight pyrexia, and when fully developed consists of vesico-pus- tnles varying in area from a pin's head to a three- penny piece. The spots are usually quite distinct the one from the other, and only run together if they are developed near to one another. They are also superficial i. e., without painful or hard bases as in ecthyma. The scabs that form are light-yel- low in color and look "as if stuck on," and when removed they disclose a red surface. The diseased spots begin as " little watery heads." Each spot runs a definite course of a week or ten days. The isolated and discrete character of the disease may be masked in the face and head, by the excitation of an eczema, or by the running together of the vesico-pustules, either from scratching or, as before stated, by crowding together; but in the latter case the characteristic features seldom fail to pre- sent themselves in the majority of cases in all parts of the eruption in its early stages. The disease is inoculable. Treatment. The scabs should be removed by bathing or oiling, when it is only necessary to apply to the part beneath, a weak ammonio-chloride of mercury ointment (gr. v to oj) night and morn- ing, for a few days, and the eruption will generally speedily disappear. 40 THE DESCRIPTION AND Dysidrosis is an inflammation of sweat follicles, which we have described as a distinct disease, con- sisting firstly in an excessive secretion of perspira- tion, which however has a difficulty in escaping and is retained, distending the sweat ducts and glands to a greater or less extent. Of course serum is also poured out from the inflamed parts as well, so that the reaction of the fluid discharge is alka- line. It occurs in weakly persons who are the sub- jects of nervous debility, and often in those who readily and profusely perspire. It occurs in winter as well as in summer. If well marked, it may be attended with acute miliaria of the greater part of the body, but the characteristic eruption is seen about the hand. At first the distended sweat fol- licles are seen as small boiled sago grain-like bodies imbedded in the skin of the tips, sides, and bases of the fingers, and more or less over the palm of the hand. As the fluid increases in amount actual vesicles and bullae form, which, however, rarely discharge, but shrivel up ; then the cuticle gets macerated and peels off, exposing a reddened hyperaemic derma, but it never discharges like an eczema, although not unfrequently it is mistaken for it. The rash begins as a distension of, and is a disease of, the sweat follicles. It sometimes lasts a considerable time, until, in fact, the pr.tient re- covers from the debility before mentioned as so often accompanying this disease. Treatment. At first diuretics should be given, TREATMENT OP SKIN DISEASES. 41 especially in gouty subjects or those in whom the urine is loaded or scanty, to be followed up by suitable tonics, especially quinine and iron. A cool regimen should be adopted, hot drinks avoided, or whatever will increase the perspiration. Locally, if the body generally be affected with miliaria, alkaline baths may be prescribed, but the chief thing is to soothe at the outset by wrapping the parts in some bland or oil}- substance such as carron oil, and subsequently using a slight as- tringent, as (76). In some cases patients affected by dysidrosis are vei'y weak, and in these cases the disease may lapse into a semi-chronic state, and then a long course of tonic treatment must be adopted. Ecthyma is characterized by the development of large isolated pustules which have hard and in- flamed bases and are painful. These pustules give rise to unhealthy ulcerations of a greater or less degree, and the crusts that form are large, dark, and firmly adherent. This disease occurs mainly in the badly nourished and cachectic. It may be excited by local irritants; in children especially by scabies; in elderly persons by pediculi. In fact, the majo- rity of cases of ecthyma are secondary to one or the other of these two diseases ; nevertheless the pustules may be excited by scratching alone in the badly nourished. Treatment. If the ecthyma is secondary to scabies or phthiriasis, these diseases must first be 4* 42 THE DESCRIPTION AND treated in the usual way, and then Ionics may !><> administered subsequently, when the ecthyma will disappear. It may be necessary to apply locally (35) or (60) to heal the nlcerations. If the ecthyma be idiopathic it will probably be desirable to give aperients and rectify existing cachexia or debility by good food and tonics, such as (92 , (95), (103) with or without cod-liver oil, applying the local remedies mentioned above. If there be marked ul- ceration the sores may be cleansed by two or three applications of iodide of starch (52) or iodoform, and subsequently dressed with (28), (79), or (81). Eczema is an inflammation of the skin character- ized b} T aero-purulent discharge which stiffens linen and dries into thin, yellow crusts; it is, in fact, a catarrhal inflammation of the skin. It begins by a serous effusion into the papillary layer of the skin. The effused fluid finds its way into the rete, uplifts the cuticle into vesiculation, and escapes free upon the surface, thus constituting the discharge which continues a greater or less time. Coincidently with its escape the fluid, which contains much fibrin, be- comes more or less purulent, and there is a large amount of inflammatory cell-growth in the inter- stices of the stretched-out rete cells and in the tissue of the papillary layer. If the disease becomes chronic the cutis is altered by chronic inflammatory induration to a varying depth. Eczema, therefore, begins as a "serous catarrh," and is followed by sup- puration and inflammatory infiltration into the skin. TREATMENT OF SKIN DISEASES. 43 Some think that eczema does not necessarily discharge, but this error probably has arisen 1'rom the fact that many other diseases have been included under the term eczema, such as parasitic eruptions, lichen, and pityriasis. These do not discharge, and hence the statement that eczema is not necessarily accompanied by discharge : but it is important to remember that in true eczema there is always " sero- purulent" fluid effused externally. There are three varieties of eczema viz.: (1) E. simplex, which is generally localized to one or two places, and consists at first of crowded vesicles seated on a red base, which, when they rupture, give place to a red discharging and then crusted patch. It is not attended by any marked general disturbance of the system, though perhaps by debility, and is frequently excited l>y local irritants such as heat, cold, scratching, irritant dyes, etc. (2) E. rubrum, which is the inflammatory form and is attended by more or less constitutional dis- turbance and by gouty or dyspeptic symptoms. In this form the local inflammatory signs are very marked, that is to say, the parts are hot, swollen, tender, itchy, excoriated, and they discharge and crust. This eruption often attacks the flexure of the joints, especially at the elbows, knees, and axillae. (3) E. impetiginodes or pustulosum, which is cha- racterized especially by the free formation of pus, free discharge, and free yellow crusting. It is mostly observed in strumous subjects, especially in 44 THE DESCRIPTION AND Bach children when badly nourished and the victims of bad hygiene. These varieties occur in different situations on the body. Each variety has its stage of erythema, papnlation, vesiculation, and pustula- tion, and "discharge." These stages have been often made into varieties of eczema, a proceeding at once unphilosophical and unclinical. Treatment In E. simplex an}* causes of local irritation are to be removed, and the part protected locally by dusting it over with such as (48 or 49), or (14) may be applied. This should be followed up by (7G); whilst internally quinine and iron (109) is given, since the outbreak or its persistence is very often favored by debility. E. rubrum requires more active treatment. Any gouty tendency must be carefully met by appropriate dietetic and other ivnicdies, all stimulants being at first avoided. The part locally is to be soothed by absorbent powders, or bathing with poppy water, and subsequently dressed with linimentum aqua calcis, or should there be much burning (18), (41), or (74). Sometimes, indeed, all the remedies will fail until a loaded sys- tem has been relieved by aperients or excess of acid generated in the system be corrected, or dyspepsia remedied. When the part affected is less irritable and red (62) or (76) may be employed with tonics, especially arsenic, with alkalies, iron, or quinine (90), (107), (108). If the part become much thickened and indolent, an alterative mercurial course with bark will be found beneficial, at the TREATMENT OP SKIN DISEASES. 45 same time that weak mercurial ointments are applied (00), to be followed in the still more chronic cases by blistering, if need be. E. impetiginodes requires the internal use of cod-liver oil, iron, and quinine, with suitable food, and locally the application at the outset of simple oil to free the part from crusts, followed by the linimentum aq. calcis, and then a weak white precipitate ointment, as for instance gr. iij to the sj or (62). In addition, certain local varieties are described which it will be desirable perhaps to mention here. E. capitis is almost synorrymous with E. infantile. The child will be found pale, and very likely more or less cachectic. Bad or insufficient food is at the bottom of the majority of such cases, and the remedies required are better food, cod-liver oil, arsenic, and steel wine. Cleanliness and the use locally of the remedies stated to be appropriate for E. impetiginodes must be carried out, for E. infantile and E. capitis take on the characters for the most part of that variety, though occasionally those of E. rubrum. Should there be any difficulty in re- moving the crusts the head or face may be kept soaked in oil until they are loosened and detached. In the adult, E. capitis occurs in the gouty, and requires similar treatment to E. rubrum. E. mammae is frequently excited by scabies. E. nianuum et pedum and E. genitale are ex- amples of E. rubrum. The former is often excited by flour in bakers, by sugar in grocers, and by soda 46 THE DK8CRIPT10N AND iii washerwomen. E. fje.nitale is benefited mostly by the use of (74) ; E. manuum by the remedies adapted for E. rubrum ; E.pedum by rest, great cleanliness, and absorbent powders, followed by carbolic lotion, and finally strapping with emplas- trum diachyli. In eczema of the legs, if there be much cedematous infiltration the liberal exhibition of diuretics in conjunction with rest, careful bandag- ing, and the use of (76) or a weak mercurial oint- ment, is all that is needed to effect a cure; though often tonics and good feeding are very useful ad- juncts. Other remedies will be found on reference to the cutaneous pharmacopoeia. Elephantiasis. This term is used as a generic one for two distinct diseases: the one is the E. Arabitm, or tropical big leg, or Elephant leg (see Hucnemia) ; the other is the E. Grxcorum, or the true leprosy. E. Greecorum is observed in two chief forms viz., tubercular and the ansest/n-ffi: The tubercular form is known in its full}' developed stage by three sets of symptoms, (a) discoloration of the skin, of a light coffee hue; (b) deposit of a new growth in the skin in the form of dull red tubercles or infiltrations ; and (c) amesthesia of dif- ferent parts, especially the extremities, due to the deposit about the superficial nerve-trunks, of the same new growth as that which invades the skin. The skin deposit is chiefly found about the face and ears, so that the eyebrows, cheeks, forehead, nose, and its aho, being greatly thickened, give the conn- TREATMENT OF SKIN DISEASES. 47 tenartce a leonine appearance. In the anaesthetic form the deposit in the skin is not so marked, but anaesthesia is well developed, and eruptions of bulLie which leave behind atrophous spots, and also dull quasi-psoriatic but anesthetic circular spots of eruption are observed. The hands are often dis- torted, and the fingers contracted, so that the hand assumes a claw-like aspect. Epithelioma, or Epithelial Cancer. This affec- tion occurs in elderly persons, and attacks by pre- ference the lower lip. It begins as a hard lump, which makes the lip feel swollen and ' ; pouty." This lump soon cracks in the centre from the setting in of ulceration ; and when this takes place the progress of the disease is often very rapid. The ulcer, which is now soon produced, is foul, and its edges everted, indurated, and undermined. The glands under the jaw are enlarged and in- durated. The treatment consists in excision. For the variety denominated Rodent Ulcer (see further on). Erythema, or simply redness (hypenemia). Redness may form a part of very many dissimilar diseases, all those, in fact, in which inflammation or active congestion occurs. Reference is here made, however, particularly to erythemata, which in themselves constitute the condition or disease requiring treatment. There are two classes. The first group of erythema cases includes all those instances of hyperremia which are excited by 48 THE DESCRIPTION AND local irritants of various kinds, as parasites, heat, cold, friction, scratching, flannel, etc., and also coin- prises such as are induced by the rubbing together of two folds of skin (inti-rlriyo), and are accom- panied by a mnciibnn discharge. The treatment of these cases consists in removing all local causes of irritation, and simply soothing the part by such remedies as (13), (14), (3G), (74), followed by (10), (39), or (72). In intertrigo (48) and (40) are specially useful; and in some cases it is necessary to give children tonics, particularly steel wine and cod-liver oil. In the intertrigo of old and fat people diuretics and alkalies, followed by tonics and dressing the parts continuously with (13) or (7G), is a good mode of treatment. The second group of cases includes the erythe- mata connected with general p3 r rexia, and often with a rheumatic diathesis. There is rather more swelling than in the slighter forms, and a certain amount of effusion, so that the erythema runs on to papulation or the formation of irregular, and some- times large nodular swellings; hence the terms E. population, E. tuberciilalnm, and E. nodosum, and E. mnlliforme, which latter is used by Hebrato in- clude all the forms indicated by the preceding terms. Generally the rashes designated by these terms have a more or less acute onset, ushered in by headache, malaise, and the like symptoms, and then hyperannic blotches appear about the hands, arms, legs, or trunk, and the blotches may get more or less un- Til EAT ME NT OF SKIN DISEASES. 49 even or " knotty" from effusion, and a purplish tint quickly develops, especial!}' at the edges of the patches ; and finally the whole thing in a few days fades away with changes of color, like a bruise. E. nodosum occurs about the leg as oblong tuberose swellings about the size of a walnut, or even much larger, with a bluish periphery and quasi boggy feel in the centre. Rheumatic pains accompanj- this forms of erythema. The treatment of the members of this second group in the slighter forms consists in giving mild aperient salines, followed by quinine, whilst locally some simple astringent wash, such as (74) or (19), may be applied. In the severer cases it may be necessary to relieve a loaded state of system by (95) or (96), before giving quinine, and locally to use similar measures as in the less severe forms, or apply powders, such as (48) or (49 . Favus, see Tinea favosa. Fibroma is characterized b}^ the occurrence of outgrowths of fibrous tissue, covered by integument of ordinary aspectand feel. These tumors after a time become pedunculated. Their structure is that of a lax connective tissue, peculiarly rich in cells at certain parts. Sometimes the tumors show a dis- position to ulcerate, and throw up exuberant granu- lations. Treatment. If it be important that the tumors should be got rid of, they may be removed by the knife or the ligature. 5 50 TFIE DESCRIPTION AND Fish Skin Disease, see Jchthyosis. Follicular Hypersemia is a common accom- paniment of many diseases, and particularly of those attended by pruritus, for in these it is readily ex- cited by scratching, as in scabies, eczema, and phthiriasis. It gives rise to red papules, which are seen to be seated at the hair follicles in part, and partly to be hypenemic papillae, erroneously said to constitute lichen. The condition demands soothing remedies. Fungi. For the names of the several fungi causing parasitic diseases, see Tinea. Furunculus. It is scarcely necessary that " boils" should be discussed in any considerable detail in this place. They are usually described as rounded, painful, circumscribed inflammations of the skin, involving the connective tissue, and there- fore more or less deeply seated, with hard, indu- rated, and inflamed bases. Slow suppuration goes on, and the central portion sloughs out, and consti- tutes what is called the "core." In reality the anatomical seat of boils, in the majority of cases, is a hair follicle or the attached sebaceous gland, with more or less participation of the cellular tissue around. In some cases the follicular origin of boils c*imot be made out, hence the division into folli- cular and cellular tissue boils. It is open to ques- tion whether the "core" be always an "exudation," or a gland which has died in consequence of the in- tlainmation. When a boil forms, pain is first felt, TREATMENT OP SKIN DISEASES. 51 and then a lump accompanied by tension and red- ness : this enlarges and suppurates. In "cellular tissue boils" gangrene may occur. These are found mostly on the scalp, neck, limbs, and especially the thighs of marasmic adults, and often children. Boils occur in those whose vitality is depressed by defective or depraved living, mal-hygiene, or expo- sure : also in those whose blood current is charged with nitrogenous waste products, and in diabetic patients. An exclusive meat diet, stale or unsound meat, over-fatigue and exercise are other excitants. Local irritants excite their formation, and they may accompany disease in which scratching is freely practised, as in scabies, prurigo, eczema, phthiriasis, etc. Boils may be epidemic, and then occur often- times when erysipelas is rife. Treatment. The formulae useful for boils are specially (95), (96), (108), and the mineral acids, internally, and (35), (79), and glycerine of bella- donna externally. Patients with boils should have a carefully regulated diet, and obtain fresh air by change to the seaside or of occupation. Fresh yeast taken in tablespoonful doses three times a day is often very efficacious. In very debilitated persons the free exhibition of red wine or porter may effect the dispersion of the furunculi. Some practitioners find great benefit from the use of carbolic acid, or acid nitrate of mercury to the boils to absorb them. Grocers' Itch is similar to Bakers' itch, only that it is caused by the irritant action of sugar. 52 TFIE DESCRIPTION AND Gutta rosaeea, see Acne rosneea. Herpes is characterized by the occcurrence in circumscribed patches of one or more groups of vesicles, seated upon .an inflamed base. The develop- ment of the disease is attended with smarting and tension, if not acute pain, and pyrexia is often pre- sent. The vesicles are distinct, large, and chambered. They do not burst, but the transparent contents be- come milk}', and they then dry up, forming light crusts that fall in a few days, leaving only a slight reddish stain behind. Each crop of vesicles runs a definite course. Herpes ma}^ be symptomatic or idiopathic. The former kind occurs in the course of febrile disturbances of different kinds ; the latter may be general or local. There is a general form of rare occurrence, beginning by pyrexia, followed by the development of herpes on the skin and the inside of the mouth and throat. The disease lasts ten days or so. The localized form is commonly met with about the lips, prepuce, and the course of one or more intercostal nerves. According to its situation, form, and appearance, so various designa- tions have been applied. Thus, one form is generally known as H. zoster or shinyles, and is made up of several patches or collections of ordinary her|>r<. distributed along the course of a nerve, and uni- lateral in its extent. "When there is a central vesi- cle with a surrounding ring of herpes, and two or more circles of colors like those presented by a fading bruise, the form is called //. m, and is some- TREATMENT OF SKIN DISEASES. 53 times seen on the back of the hand. If the disease take simply a circular form, it is often styled H. circinatus. Treatment This consists in applying some simple soothing unguent, and exhibiting salines, fol- lowed by quinine if need be. It is necessary in herpes zoster to protect the eruption from rubbing and irritation by dusting with (48), (49), or covering the part with cotton-wool. Sometimes considerable pain and discomfort are left by the eruption, and relief may be given by morphia ointment, opiate poultices, subcutaneous injection, or quinine in large doses. Hydroa is a term much misused. It has been applied particularly by English and French writers to Herpes iris, and the bullous eruptions (?) pro- duced by iodide of potassium. It was given by Bazin originally to a disease which stands midway between herpes and pemphigus, and occurs in arthritic (gouty) people, and attacks the cutaneous and mucous surfaces. It lasts two to four weeks, is apt to recur and to become chronic, and appears mostly in the spring. In some cases there are vesi- cles (H. vesiculeux} scattered over the backs of the hands, wrists, and about the knees, and also the mouth, developed out of red papules. In other cases the vesicles are varioliform (H. vaccini- forme) ; in others there are small bullse of different sizes, but none above that of a split pea, these bullae being often grouped. In fact, there are transitional 5* 54 THE DESCRIPTION AND stages between minute vesicles on a red base and patches of herpes, there being frequently a mixed condition. The treatment consists in defeating the ill effects of M-orry, anxiety, and depression; in regulating the diet, prescribing change of air, and tonics, especially quinine. Hydroadenitis is an inflammation of the sweat glands a condition that commences by the appear- ance of small lumpy swellings like blind boils, but which do not suppurate, though remaining some time painful, tender, enlarged, and of a dull red color, like huge acne indnrata spots, only that there is no central pustular point or follicular orifice. Treatment. This consists in allaying the local inflammation by ordinary measures, and subse- quently painting with collodion, or stimulating tin- places when indolent with the application of the acid nitrate of mercury; or, should this not suc- ceed, subcutaneous puncture may be employed. Hyperidrosis, or excessive sweating, frequently comes under our notice in a variety of diseases. It is said to be a "critical" occurrence in certain fevers at the time of convalescence, and is common as a part of hectic fever. It may be a natural defect, and often occurs about the feet and hands of certain people. Treatment. In the class of cases mentioned im- mediately above, a general tonic plan of treatment must be adopted, with the utmost cleanliness, and some such local application as belladonna or alum. TREATMENT OP SKIN DISEASES. 55 Should the sweat have macerated the cuticle be- tween the toes and excited an eczema, the parts must be constantly bathed, some absorbent powder used, as (48), (49), and then such as (10), (12), (14), (It), etc. Ichthyosis is characterized by the presence on different parts of the body of an incrustation of blackish hue, resembling masses of dried mud caked on the surface. This caking stands out from the level of the skin some two or more lines, and is pretty firmly adherent. It can, however, be broken up into little squarish masses. The incrustation covers a varying extent of surface either on a leg, arm, knee, or shoulder. Beneath the masses the skin is dry and shrivelled ; in some places the pa- pillae are hypertrophied, whilst in others the orifices of the sebaceous glands are very distinct, and into them are fitted little plugs of epithelial and fatty matter projecting from the under surface of the cake. These changes are accompanied by a general cachectic state of the skin, which in the parts not intrusted is dry, harsh, dirty looking, scaly, and not perspiring. The disease is mostly congenital, or it develops soon after birth. The microscope discloses hypertrophy of the skin, the papillae espe- cially being enlarged and elongated and covered with very numerous strata of cuticular scales. The latter, together with sebum, make up the caked masses. A slighter form of the disease in which the surface is dry, harsh, dirty looking, and more ft 6 THE DESCRIPTION AND or less inelastic and scaly, is called xerodermn, but both these conditions are phases of one and the same disease, and often concur. Treatment. The disease is incurable. No remedy seems forthcoming which is of any avail against it, though the coincident debility may be remedied. Still patients may be made comparatively comfort- able by bran baths and free oiling of the surface. The caking may be got rid of by wet compresses, alkaline baths, bathing in simple baths, or rubbing in grease or glycerine. Impetigo is a pustular eczema, see Eczema. There is a specially contagious variety, see Conta- gious impetigo. Intertrigo, see Erythema. Itch, see Scabies. Keloid is a h\ pertrophic outgrowth of the fibro- cellular tissue of the skin. There are two forms, the idiopalhic and the traumatic, the latter origi- nating in an excessive growth of the tissue of a soar following the use of the surgeon's knife or the applications of acids and the like. In the idiopathic form, a firm, prominent, palish colored nodule ap- pears on the skin and sends out processes, as it were, from its periphery, which by their contraction pucker in the skin around towards the central mass. The contractility of the keloid tissue indeed is cha- racteristic. Treatment consists in avoiding all irritation of the keloid growths. If removed they recur. TREATMENT OF SKIN DISEASES. 57 Kerion, see Tinea kerion. Lepra is an old term for psoriasis, and especi- ally that form which consists of circular rings of disease. JLeucoderma signifies "white skin," and con- sists in deficiency of pigment in a part, without any structural alteration whatever. It is a disease ob- served chiefly in those who have resided in tropical climates, and it is probably due to some nerve pare- sis. In private practice it is usually seen affecting the backs of the hands, the neck, and adjacent parts, or the genital organs. It often improves greatly, and sometimes disap- pears under the use of general nervine tonics and galvanism of the spine. Lichen is characterized by the presence of solid fleshy papules about the size of millet seeds, which preserve their characters as papules throughout their existence, and are accompanied by marked itching. The skin generally, moreover, is usually dry, somewhat thickened, and often of muddy as- pect. The eruption may appear as scattered papules (L. simplex} attacking one or more regions, or even the greater part of the trunk, and more rarely about the extremities: sometimes as groups of papules (L.circumscriptus}. Often the lichen attacks the backs of the hands, and then but secondarily may become inflamed and give out a discharge ( L. agrius). It is in this situation excited by the contact of irri- tants, as sugar and flour, and then bears the name of 58 THE DESCRIPTION AND Grocers' or Bakers' itch (vide these). If the papules are seated at the hair follicles, giving the surface a dotted, or even on a small scale a rasp-like appear- ance, the name L.pilaris is given. So called L. liai- s, buttocks, lower part of the abdomen, and outer part of the forearms. The disease is termed P. milts if the papules are small or limited in extent, or the itching, and disease generally, not severe. When the disease is well marked, the papules crowd to- gether in certain situations in patches, especially on the legs : they are felt under the skin before being clearly discernible to the eye, and the itching or disordered sensation termed formication, is like creeping of ants. To this condition the term P. formicans is given. In certain cases where the dis- ease is extensive, and more or less congenital and persistent, it is called P. agria or ferox. Eczema here supervenes or more or less suppuration occurs, with glandular enlargements in the groin, whilst the skin feels thickened and indurated in the chronic stage. In England the severer form is not common. The writers have only met with few cases, and the disease of milder type has occurred in their experi- ence in those exposed to alternate heat and cold in their occupation, and who have become debili- tated. Treatment. This should consist in improving the general health, in given arsenic (90 et seq.), or ( 10G), in the employment of vapor and alkaline baths, and the use of sedatives, chiefly ( 23), (30;, (34), (69), (71), (74), as they may best suit. Pruritus, or itching, is an accompaniment of most skin diseases, especially eczema, lichen, pru- TREATMENT OF SKIN DISEASES. 71 rigo, urticaria, scabies, and phthiriasis. But it may arise in the skin without any eruption, and then it is usually due to the circulation of some acidity, as bile products, urea, uric acid, etc. ; or to some dis- order of the nerves ; or it is excited by some local irritant, as, for instance, about the rectum by asca- rides, about the head and pubis by pediculi, about the body by flannel, friction, or scratching. It must be remembered that the appearance of the skin is always altered by scratching, as it causes follicles and papillae to become hypeneinic and pro- minent; their apices get scratched off, and a drop of blood exudes and dries as a speck. This'pruritic rash is most erroneously termed prurigo (which see). In old people pruritus (senilis) occurs as an hyper- jEsthesia, and consequent on the general atrophy of the skin ; but in such persons the causes mentioned above come readily into play. The following hints relative to the more common causes of itching may be found useful. Itching increased at night by the warmth of the bed, with a pimple rash about the front of the arms and the bod}', is suspicious of scabies. Itching in old peo- ple about the shoulders and back, of phthiriasis. At the back of the head in children, of pediculi in the head. Itching, with eruption about the fork of the thigh, of parasitic disease and intertrigo (ex., eczema marginatum). Itching of capricious charac- ter, suddenly coming and going here and there, es- pecially at night, and without visible eruption in the 72 THE DESCRIPTION AND d:i yt imc, is suspicious of urticaria. In the winter time especially it is not uncommon for the skin in certain persons to be irritable, particularly towards even- ing, or when the clothes are taken off, and the air obtains access to the skin. The itching in such cases has been termed pruritus hiemalis, or winter pruritus. It occurs in various parts of the body, but more especialty about the thighs and legs. In some cases no eruption can be seen, but in others there is decided turgescence and prominence of the hair follicles, enough in degree perhaps to consti- tute lichen pilaris. The disease is supposed to be "neurotic," but it is probably due to inactivity of the perspiratory function >n the majority of cases: at the same time there is frequently defective excre- tion of nitrogenous matters and bile products. It is not exclusively a winter affection, though most common at that time because of the inactivity of the skin. Scratching, it must be remembered, may excite lichen, eczema, ecthyma, and the like, whereby the primary disorder may be masked. Treatment. A number of remedies for itching occurring in connection with particular diseases will be found in formula} (18) to (44), and scattered else- where. Starch, borax, or alkaline baths should be administered when the skin is l^-peraemic or irritnble, and in the early stages of pruritic mischief. In the indolent aspect, or later stages, sulphuret of potas- sium or mineral acid baths are of decided ellieney. As regards internal treatment, this varies with the TREATMENT OF SKIN DISEASES. 73 case. Itching due to the circulation of retained ex- creta may be relieved by appropriate aperient and alkaline remedies, whilst nervine tonics will be suit- able for the " neurotic" itching. All parasites and other local irritants must be destroyed or removed (.see 209 el seq.), and flannel especially should not be allowed in contact with the skin in severe pru- ritis. Further information will be gathered from the special descriptions of the several diseases men- tioned here with which itching is associated. Psoriasis is a disease characterized by hyper- trophous growth of the epithelial layers of the skin leading to a heaping together of whitish silvery looking masses of scales, which on being removed disclose a hypersemic cutis with papillae, enlarged by engorgement of the vessels. The chief seats of the disease are the elbows, knees, and head, but also the body and limbs generally. The disease is often hereditary. It begins by the development of small spots, P.punctata: these gradually enlarge and look like drops of mortar, hence the terra P. gnttata. Soon many acquire the size of a sixpence or shilling and are generally round, and now the name P. nurnmularis or circinata is given. In some cases large patches are formed by the coales- cence of the spots, so that a great extent of surface is covered ; this is called P. vulgarits. Should patches take on a serpentine form, the term P. gyrata is used, and if the affection is veiy chronic P. inuelerala. Lastly, if the crusting is freer than 7 T4 THE DESCRIPTION AND usual and assumes a conical shape, the name P. rupioides is applied, the epithelial elements being in this case mixed with pus ; it is dependent on a strumous habit. A common local phase is P. pal- maris, likely to be confounded with syphilitic dis- ease; but the former is generally a part of a more general affection, and it does not begin nor is it limited to the palm of the hand, as is the syphilitic disease as the rule. Treatment. In children cod-liver oil, quinine, iron, and arsenic should be given if the scales an- very plentiful and silvery, see (90), (92), ( 1 06), (107), properly proportioned in dose to the age of the patient. Locally alkaline baths may be used with the inunction of oil as long as the hypenemia lasts, and afterwards some mild tar application as (70). In adults, gouty conditions must be rectified. If the skin be very b^'penemic diuretics should be exhibited, and the skin simply soothed b}' alkaline baths and oil inunction. Then arsenic may be givi-n freely, (90 et seq.) and (106 el seq.). Locally at first mild mercurial ointment, (62), (fi3), and lastly tarry preparations, (68), (69), (70), (71), may be used. In no disease is more care needed to unravel the exact combination of conditions conducing to the disease. (See Remarks, Part I., p. 29.) Purpura is characterized by minute extravasa- tions of blood, at first bright red and afterwards indigo color. The size varies from pin points to large specks and blotches, and these even run into TREATMENT OF SKIN DISEASES. 75 patches scattered over the surface, especially on the legs. Slight pyrexia accompanies it, and the erup- tion cannot be effaced by pressure. This is P. sim- plex. A more severe form in which haemorrhage takes place more freely into the skin, and from the mucous surfaces, is known as P. haemorrhagica. Treatment. The latter condition requires very great care. The former: rest, acids, quinine, per- chloride of iron, turpentine (100), gallic acid, etc. Ringworm, see Tinea. Rodent ulcer is the least malignant form of cancer. It rarely occurs before the age of fifty, and begins as a solitary, indolent tubercle somewhere in the upper two-thirds of the face. This tubercle after two or three or several years cracks and shows a tendency to ulcerate, the ulcer when formed being bounded by hard sir.uous edges which are not under- mined ; the surface is cleanish and no glands become implicated, nor is there any cachexia. The disease makes very slow progress and is painless. Treatment. Free excision at the earliest possible moment with or without the subsequent use of caus- tics. If removed effectually the disease does not return. For caustics, see (3), (4), and (5). Roseola is a hypenemia of a rosy hue, either symptomatic, and then part only of certain acute febrile disease, as rheumatism, vaccinia, cholera, etc. . or idiopathic, as seen mostly in children during change of season (R. infantilits), and in connec- tion with slight stomach derangement. It may be 76 THE DESCRIPTION A N T l> general and resemble measles, but there are no true catarrhal symptoms; the rash is not crescentic in character, and is more rosy than that of measles. Though it may be distributed more or loss wholly over the body, still it is decidedly patchy in charac- ter. It may occur in rosy circles and rings (It. annulata), especially about the limbs, and in the autumn or summer (R. aitiiimnalis and It. sestiva). Treatment. In the idiopathic forms salines and laxatives should be exhibited and some simple oint- ment used. Rupia. In this eruption small flattish bulla3 are developed, with at first clearish contents, quickly becoming like a mixture of blood and pus. The bullae dry into dark thick scabs hiding unhealthy ulceration. The crusts increase by additional dis- charge which " dries on" as it were from below as the ulceration increases. They are consequently conical, stratified, dark and adherent, and the "cockle-shaped" crusts are in fact diagnostic of rupia. Should they be moderate in size the disease is termed ft. simplex, if large and prominent, It. prominens ; if the ulceration is excessive and pha- gedsenic, It. escharolica. The disease is always syphilitic. Treatment. This should be as for tertiary sy- philis (see 84 et scq.). The ulcers may be cleaned by iodide of starch and dressed with black-wash or (61), (81), (82), (83). TREATMENT OF SKIN DISEASES. 77 Scabies or Itch is caused by the burrowing in the skin of an insect called the acarus scabiei. This burrowing excites much itching and some h}y the acarus in its burrow, which is characteristic of scabies, is as follows: Where the acarus enters, a vesicle forms, and the animal's course is traced by a slightly raised straight or tortuous line (cuniculus) from one to many lines in length, at the end of which the pre- sence of the imbedded intruder is marked as an opaque spot generall}'. The furrow or cuniculus becomes discolored by dirt, and then has a dark tint with darker dots along its course, probably the excreta of the acarus. Now these furrows are mostly seen in the adult in the interdigits and about the wrists in the earl y stage of the disease, but sub- sequently about the penis at its upper line and other parts of the front of the body. In children the buttocks and feet may alone be the seat of scabies. Of course the furrows lose their characteristic ap- pearance after a good scratching, as they are torn open and the acarus frequently dislodged. If pa- tients are cachectic both the vesicle and the furrow may suppurate, as in so-called pustular scabies. The "secondary rash" consists of hyperamic folli- 7* 78 THE DESCRIPTION AND cles and papillae forming papules, of ecthymatous pustules excited by scratching, and sometimes of eczema and urticaria. The results of irritation are seen in early scabies in the adult on the front of the forearms and about the wrists ; in chronic scabies on the front of the belly and on the upper part in front and inner surface of the thighs ; in children about the lower limbs, buttocks, and abdomen. Scabies is accompanied by marked itching, which is always worse at night, and several members of a family are often the subjects of attack at the same time. Cuniculi are absolutely diagnostic, but if these cannot be detected, itching at night in persons who have a pimply rash in the interdigits or fore- arms or upper line of the penis is very suspicious, and much more so if several persons in the same family are affected similarly together. Scabies in Private Practice. It is impor- tant to remark that scabies often differs very much in aspect, according as it occurs in hospital or in private practice. Amongst the poor, and especially the uncleanly, the burrowings of the acari in the skin are attended with the formation of papules, vesicles, pustules, wheals, etc., in abundance. But amongst the well-to-do, and particularly those who observe great cleanliness, the ordinary results of the irritation produced by the acari may be almost, if not entirely, absent. So that if a student were to be guided by the ordinary descriptions given in books of scabies, he would certainly not be able to TREATMENT OP SKIN DISEASES. 79 diagnose the scabies present. The disease would not answer in description to papular, pustular, or vesicular scabies, and yet true scabies might be present. We have seen several cases lately in which patients complained of itching intensified at night in different parts of the body, and in whose skin nothing could be detected but a few cunicnli about the hands or the penis, and an apology for a vesicle here and there. We have seen a multi- tude of acarian furrows about the hands and other parts in a case of scabies, and nothing else. In other cases we have observed just a few very fine, delicate, pale, flesh-colored papules, the result of irritation set up by acari present in the skin, and nothing more, and these, which were lichenous papules, were difficult to make out. In all cases in which a patient complains of itching aggravated at night, even though there be none of the ordinary evidences of scabies present, yet a diligent and active search for cuniculi should be made about the hands and penis. We have known patients treated with powerful internal remedies for " pru- rigo," lichen, and the like for weeks, whilst scabies, which existed, was wholly unsuspected because there were no papules and pustules present. Pa- pules, pustules, and vesicles are indeed accidental accompaniments of scabies, which should be looked upon as consisting essentially of the acari in their furrows (cuniculi) i.e., the real scabies, and the phenomena of irritation (papules, pustules, etc.) 80 THE DESCRIPTION AND superadded, which, under certain circumstances, may bu entirely absent. Two or three cases of scabies limited to the penis have recently come under our notice. In all of the cases careful search detected cuniculi. In two, suppurating buboes were produced by the irritation, and the disease was thought to be syphilitic. The diagnosis was rendered easy by the absence of any decided indu- ration about the scabies spots, their vesico-pustular origin, pruritis intensified at night, the presence of cuniculi, and the absence of any concomitant evi- dence of syphilis. Treatment. The majority of cases are cured by a free inunction night and morning of (114) or (120) for three nights and mornings. The patient must thoroughly wash himself, and if free from itching on the fourth night may be regarded as well. It is important not to overdo the sulphur inunction, but cease it after a da}' or two, for it often sets up in itself irritation, and the continuance or increase of itching is taken for an aggravation of the disease. After three days' treatment the remedy may be lightly applied to any solitary vesicles that make their appearance. If any parts feel hot and tender (74) should be used to soothe. In chronic scabies it may be necessary to make freer and more potent applications (110 et seq.). Often the free use of storax ointment will be found most effectual ; and so also ointments of iodide of potassium and car- bolic acid. TREATMENT OF SKIN DISEASES. 81 Scleroderma is a disease due to hypertrophous growth of the fibro-cellular tissue with infiltration by coagulable fluid. In consequence the skin be- comes first of all stiff, then hard, and then indurated like leather, and it cannot be pinched up or wrinkled. The disease is, as a rule, one of adult ,life; it may come on after exposure, perhaps suddenly and may affect one or more regions, or more or less of the body. It frequently attacks the nape of the neck, or the front of the chest, or a limb. The hardness and induration, which is raised and yellowish look- ing, may take the form of bands, or occur continu- ously over an extensive area. The stiffness pro- duced may interfere with respiration or the move- ments of the face or joints. In some cases it occurs in conjunction with morphoea, or the edge of the sclerodermic band may present the aspect of mor- phoea. Treatment. The disease may gradually diminish under general tonics internally, and friction with oil externally, but treatment, as a rule, is not found to be very influential in curing this disorder. Scrofuloderma. This disease commences as indolent, painless, livid tubercles that gradually soften up and give place to foul, ragged, unhealthy ulcers with pallid granulations, free secretion, and may be crusting. Occasionally the ulceration is superficial and creeps along the surface. The scro- fulous features will be recognized in this disease 82 THE DESCRIPTION AND in the family history, physiognomy, physical condi- tion, glandular complications, etc., in the patient. Treatment consists in administering cod-liver oil, iron, quinine, and good food internally, and locally in the application of iodide of starch to cleanse the foul sores, and then some mild astringent; whilst, in the later stages, soap and mercurial plaster is used with iodine fumigation. Seborrhoea. This consists in an excessive secretion of sebum. It may be more or less oily, and give rise to a greasy skin (S. oleosa): or it may dry into fatty plates, consisting of dirty white flat scales that feel greasy, and are easily detached, ex- posing a very slightly reddened and non-excoriated skin in which the sebaceous glands are more distinct than usual. This is the common form of seborrhoea, and constitutes what is termed "dandriff" or "scurf" in the head. Thirdly, the fatty secretion may take the form of little plugs distending the orifices of the glands, and then the skin feels harsh like a file (S. cornea). The seats of seborrha-a are especially the scalp and the face. It is liable to be confounded with eczema, but in seborrhoea, although the skin is reddened, there is no breach of surface as is seen when the scaliness and crusting are re- moved. The follicles are seen also to be more patent than usual, and the incrustation is also soft and greasy, and not the result of the drying of "dis- charge." Treatment. It is requisite to give tonics and TREATMENT OF SKIN DISEASES. 83 arsenic, as (90\ (93), (94), (108) : locally to get off the crusts by oily inunction, and to apply astrin- gents, as (11), (14), (25), (40), (51), (73). Strophulus or Red Gum. This term has been applied to many different eruptions, consisting of soft red papules in infants ; in one case, to hyper- semic papillae, in another to hypersemic sweat glands, and again to distended sebaceous glands. So-called strophulus, characterized by bright-red points, seated on the face and arms of children, is, in fact, a hypersemia of the papillae or sweat glands, mostly induced by the child being kept very much wrapped up, and so overheated. S. albidus is the term given to the small pearly-white specks seen about the face of children, and due to distended sebaceous glands. The hypersemic states alluded to above are exagge- rated by any stomach disturbance. Treatment. Some mild aperient and ant-acid should be given, with the adoption of a cool regi- men, and the local use of some simple soothing lotion, as (74). Sudamina is the term applied to the little vesicles formed by distension of the upper laj-er of the cuticle by sweat. They are apt to occur about the clavicles, neck, or face, but often may be seen in other parts, whenever the skin is stimulated to ac- tivity during the establishment of convalescence from pyrexial attacks, or from keeping the bod}^ too warm. They are especially frequently seen in acute rheumatism. No treatment is required, 84 THE DESCRIPTION AND as the vesicles rapidly disappear of their own accord. Sycosis signifies inflammation of the hair follicles of the beard and whiskers. It may be caused by a vegetable parasite, and then possesses special features (see Tinea sycosis), or it may arise as an idiopathic inflammation of the follicles, and then is called simply xycosis. In this latter form the disease consists in the development of pustules, pierced by a hair, scattered here and there about the hairy parts of the face. The pustules, which indicate that the whole hair sacs are inflamed, may become more or less indurated at their bases, form- ing qnasi-tubercles. If the inflammation is severe, and the pustules are crowded together, there may be considerable discharge and crusting : the derma and connective tissue textures of the affected part being involved, so that the parts are reddened, hot, swollen, and infiltrated, and the patient may suffer great pain. The disease, however, differs very much in severity. It often occurs in the debilitated, the intemperate, the dyspeptic, and eczematous. It often, too, runs a very chronic course, especially in strumous subjects, and in such cases more or less atrophy and loss of hair may result. Treatment. It is generall}' considered that epila- tion rapidly cures the disease, but this is a mistake, and, indeed, the procedure often does harm. It does good if there is much chronic inflammatory thickening involving the deep parts of the follicle TREATMENT OP SKIN DISEASES. 85 with suppuration, and should be followed by the use of a weak white precipitate ointment. The dis- ease should be treated as a simple inflammation, locally by hot fomentations and soothing remedies in the early and acute stages ; subsequently by the use of astringents, as (75), followed by weak mercurial ointments ; and lastly, tar or sulphur applications. . Internal treatment consists in the use of aperient tonics, as (95), cod-liver oil and iron when needed, and lastly, a course of Donovan's so- lution where there is much indolent thickening. Where there is much thickening, painting with liquor potassae, followed up with the use of mercu- rial plaster, is often of service, hut the disease must be indolent for this treatment. Syphilis of the Skin is met with in connection with hereditary and acquired syphilis. Hereditary syphilis is practically nearty synony- mous with congenital or infantile syphilis. This form is uncommon before the end of the second or beginning of the third week, and it is rare after the sixth month ; the usual period of its occurrence is when the child is about three weeks or a month old. No one can mistake the tainted infant ; the general aspect is more or less marasmic ; the child presents a shrivelled, " old man'Mike aspect ; the skin is dirty and muddy, has lost its elasticity, and hangs in loose folds ; it is dry, often exfoliating, and more or less erythematous about the buttocks. The cry of the child is harsh and cracked (characteristic), 8 86 THE DESCRIPTION AND and "the snuffles, produced by inflammation and u Ice rat ion of the nasal mucous membrane, are pre- sent." The disease is further characterized by the presence of mucous tubercles about the anus or mouth ; fissures at the angles of the mouth ; ulcera- tion of mucous surface ; a high arched palate ; in- flammation of the thy mus gland ; various eruptions over the body, especially about the feet and hands, in the form of erythemata or bulhu ; a subacute onychia is possibly present; and these, together with a family history of sj'philis, are diagnostic. With regard, however, to the eruption, it is gene- rally in the form of a dull-red erythema of the hands, feet, and perianal region, with or without tubercular formations ; but it may in cachectic sub- jects consist in ngly ulcerations arising out of tuber- cles, bullae, or pustules. The treatment consists in gently mercurializing the child by the use of gray powder or mercurial inunction (a small portion of blue ointment being rubbed into the soles of the feet each night), in keeping up the nutrition of the body by good food, by giving cod-liver oil and chlorate of potash, and, if the child is nursed, in giving the nurse a course of iodide of potassium. Acquired syjihilis. When in the adult an erup- tion is due to this cause, there is usually imparted to it a coppery tint, and a more or less circular form ; the general distribution of the eruption is notice- able, and generally there is absence of pain and TREATMENT OF SKIN DISEASES. 87 itching; there is a polymorphism about it i. e., papules, tubercles, and ulcers (occasioning loss of substance), etc., occur together ; cachexia, ulcerated throat or tongue, alopecia, nocturnal pains in dif- ferent parts are often concomitants ; and a history of the primary disease may be connected by different links with the present condition by a series of sy- philitic occurrences. Syphilodermata may be divided for all practical purposes into three groups ; (a) those that are byperaemic ; (b) those that have deposit (or new tissue formation) as the main feature; and (c) degenerative lesions, the result of suppuration and ulceration of the syphilitic new tissue formed in the skin. The following sketch may throw light on this subject. The first effect of the syphilitic poison upon the general system is to give rise to syphilitic fever and transitory hyperseinic lesions, as roseola and erythema. Sufficient time having elapsed for the action of the poison upon the nutrition of the textures, a second period ensues, in which modifi- cations of their normal growth take place that is, new tissue is formed (granulation or syphilitic tissue), and the results appear in the form of papular, tubercular, squamous, and pustular erup- tions, mucous tubercles, gummata, etc. But mean- while the circulating poison has caused the skin glands to inflame (syphilitic acne), and the follicles (syphilitic lichen). These commence also in hy- 88 THE DESCRIPTION AND peroemia of the sebaceous glands and follicles, but now not of a transient character, but followed up by infiltration of granular tissue into and about the parts. The nerve-trunks also may become irritated by the poisoned blood, or the deposit about them, and herpes and pemphigus occur as a consequence. A common occurrence is so-called syphilitic palmar psoriasis, which consists in a hard, indurated, cracked, scaly surface, or hard tubercles about the palm of the hand, and in connection with other signs of syphilis. The further stage of syphilis of tin- skin consists in the infiltration by the syphi- litic granulation tissue of the deeper parts, and more extensively than before of the superficial ones, whilst the patient's general health becomes cachectic. Then, in this third stage the syphilitic tissue softens up, suppurates, or ulcerates ; and this latter stage is characterized by degenerative changes in the syphilitic deposit in different parts, as is seen in ulcers, onychia^ etc. Treatment. Internally in the papular, tuber- cular, squamous, and pustular syphilides, mercurial treatment is called for, and the bicyanide pill (105) is the best form, and the pill may be given for three or four weeks, or omitted before the gums begin to be affected. See also (84 et seg.) and (104). Iodide of potassium may be given at the same time in increasing doses. In the ulcerating forms, if the patient be well nourished and pretty strong, there is no objection to a mercurial course; but where TREATMENT OF SKIN DISEASES.. 89 cachexia is marked, and the patient's condition is one of evident debility, iodide of potassium, with cod-liver oil, or iodide of iron and good food, con- stitute the best treatment. In cachectic, subjects, who are debilitated, restless, and irritable, opium given internally is of much service. In reference to iodide of potassium, it must be borne in mind that its use is beneficial in direct proportion to the duration of the disease; hence when nodes, tuber- cles, caries, and secondary ulcers are present, or when mercury has been fully used or apparently failed, the dose should be gradually increased by three or four grains every few days, until in the case of old-standing and ulcerating syphilis it reaches thirty or forty grains. In most cases the exhibition of the decoction of various woods is advisable ; the compound decoctions of sarza and guaiacum are the best; they keep the skin and bowels acting freely, and thus very materially help the elimination of the poison. When a patient 1s under the influence of mercury he should avoid stimulants, cold, and other sources of irritation and catarrh ; the indulgence in stimu- lants, indeed, is a source of infinite harm, and a common cause of aggravation of syphilis of the skin. The diet should be good and nutritious, and the administration of mercury should always be followed up by a course of mineral acids and bitters, or iron and quinine, etc. ; or tonics may be 8* 90 THE DESCRIPTION AND given simultaneously with the specific remedy, and with a liberal hand if the general health is had. Mercurial fumigation, which acts both locally and generally, is in great favor with some practi- tioners. If the skin eruption is extensive it may be employed twice or more a week. Locally, the erythematous forms require no special application, but a lotion of oxide of zinc and calamine may be used. Should they be obstinate and leave behind any papules, a white precipitate ointment may be used. The squamous and papular eruptions are relieved by calomel ointment, bichlo- ride lotion, and nitric oxide of mercury ointments. The tubercular and ulcerating forms are those which require special local medication; in the former, the weak nitrate, or nitric oxide of mercury ointments, are those more especially useful, and nitrate of mercury may be cautiously used to de- stroy obstinate indurations ; ulcers may be dressed, if painful, with a solution of watery extract of opium, or be dusted over with calomel, or be stimu- lated with the nitric oxide of mercury ointment, dilute nitric acid, and borax lotions (45), (02), (<'>'!), or treated by the local application of mercurial vapor. Should ulcers be very foul and dirty-look- ing iodide of starch (52) is a good remedy, and when ch'ansed the sore may be dressed by a weak mercu- rial application or astringent wash. Formula) (3), (7), (23), (58), (59), (60), (Gl), (80), (81), (82), (83), may be referred to. TREATMENT OF SKIN DISEASES. 91 Tinea is the generic term given to the vegetable parasitic diseases, which are here enumerated : 1. Tinea favosa or favus, caused by a fungus called achorion Schonleinii. 2. Tmea to^surans, or ordinary " ringworm" of the scalp, caused by the trichopfiyton tonsurans. 3. Tinea kerion is a modification of the last, and is caused by the same parasite. 4. Tinea circinata, or ordinary ringworm of the body, includes Burmese ringworm, Malabar itch, Chinese ringworm, etc, and is caused by the tricho- phyton tonsurans also. 5. Tinea sycosis or mentagra, or sycosis parasi- tica, is caused by the microsporon mentagraphytes. 6. Tinea versicolor, or Chloasma, or Pityriasis versicolor, is caused by the microsporon furfur. 7. Tinea decalvans, or area, or alopecia (one form), is caused by the microsporon Audouini. There are two other parasitic diseases which may be mentioned here viz., Mycetoma, or the madura foot or fungus foot of India, caused by the cliionyphe Carteri; and Onychomycosis, or onychia parasitica, alluded to at p. 64. Tinea favoso is rare in England. It attacks the young, and is known by the presence of dry, light, sulphur-colored, cup-shaped, umbilicated crusts, made up of fungus elements, and pierced in the centre by a hair from the underlying follicle. These crusts may run together into a confused mass in some cases. 92 THE DESCRIPTION AND Treatment. The point is, after getting ofF all the crusts by oil soakage, to destroy the parasite by sulphurous acid lotion, and then epilate bit by bit of the surface, and apply such parasiticides as 121, 122, 134, 136, until the microscope shows that the hair is free from fungus. Tinea tonsurans is very common, but almost unknown in the adult. It is sometimes epidemic in schools, spreading from child to child by con- tagion. The typical disease consists of circular patches, varying from a sixpence to a five-shilling piece in size or larger, having a slightly raised and scurfy surface, the hairs on which are dry, brittle, lustreless, and broken off close to the scalp. This condition is caused by the fungus attacking the hairs a fact easily shown by soaking a diseased hair in weak potash solution, and then examining it under the microscope ; it will be seen that the hair is invaded to a greater or less degree by the conidia of the triehophyton tonsurans. These conidia, when very numerous, besides crowding around the hair shaft, collect into parcels within, and separate the fibres of the shaft one from another, so that the hair is split up. These short, broken-off, opaque, dull hairs are diagnostic. Tinea tonsurans and tinea circina.la are often observed in the same subject, and, in fact, they are essentially the same, only that one occurs on hairy, the other on non- hairy parts. Treatment. If the fungus has not got deeply TREATMENT OF SKIN DISEASES. 93 into the follicle, it can readily be destroyed : there- fore the more recent the disease the more easily can it be cured. In very recent cases, two or three applications of the tincture of iodine of double strength, or a blistering, may almost if not quite cure ; this should be followed by the use for awhile of some mild parasiticide, as (121) or (122). The hair should be cut off the scalp for an inch or so around and about the diseased patches. In chronic cases, if there are many patches scat- tered over the head, the whole hair should be shaved or cut off close to the scalp ; and, if much diseased, the whole head may be soaked in sulphur- ous acid lotion (125, one part to three or four of water) for a week, to get rid of the disease on the mere surface. Then it is well to epilate over a cer- tain area day by day, subsequently apptying (130) cautiously for seven or eight or more applications at intervals of three or four days. The application will form a cake, and this should be removed by grease or soap in a day or two, or when it begins to "flake off," and before a fresh application is made. Blistering may be used instead. In getting off the caking, a number of diseased hairs come away entangled in the flakes, and this may serve in place of a repetition of epilation. It is no use applying (.136) to the surface whilst the cake is on it, but a clear surface must be obtained about three days or so after an application. It is advisable to continue the applications until the hair begins to grow out in 04 TIIE DESCRIPTION AND a natural direction and manner, and then to apply some mild parasiticide, as (128) or (134). In severe cases, epilation must be carried out again and again over tlie patches, and parasiticides must not be dis- continued as long as a single broken-off hair can be detected, or any little dark stub.s are visible, or until the hair grows evenly and well over the surface. The parasiticides that are used are very multitudi- nous; a few suggestions will be found in the Cuta- neous Pharmacopoeia. Tinea circinata, or ringworm of the body, is characterized by the occurrence of patches which are red, scaly, and itchy, circular in form, and with a well-defined edge. It begins as a little red scurfy spot which gradually enlarges, and when it has reached a fair size the skin in the central part may be apparently healthy; usually the edge looks red and scaly, the centre generally somewhat paler and less scaly, though covered with a branny de.squania- tion. The edge of the patch may be vesicular, and the disease is evidently inflammatory, though ex- cited by a fungus that spreads equally in all direc- tions, and so produces the circular form. The inflammation falls short of that which occurs in eczema. Any scurfy, red, itchy patch then on the surface of the body should always be examined for fungus elements. The fungus is the same that occa- sions tinea tonsurans, and the two diseases often occur together. In hot climates especially, the fungus sometimes TREATMENT OF SKIN DISEASES. 95 luxuriates upon the skin, particularly in the myee- lial form, and hence tinea circinata occurs in very large patches, that are very hyperremic at their ex- tending, well-defined edge, but with desquamating and slightly scaly centres. In the fork of the thigh and contiguous parts, patches that have the charac- ters of tinea circinata in an exaggerated form occur, and are characterized particularly by the festooning downwards over the thigh from the groin of a red, scaly, itchy patch, that has a well-defined circular and papular edge. This is the Burmese or Chinese ringworm. Treatment. This is always successful. The con- stant use of some such parasiticide as (122), (128), or simple tincture of iodine, or an ointment made of five grains of white precipitate and ten to twentj' of carbolic acid, will always cure the disease. Tinea sycosis In this disease, which is very rare in England, unlike non-parasitic sycosis (see Sycosis), the hairs are loosened, rendered brittle, and, in fact, changed as in tinea tonsurans, and the disease is to be treated in a similar manner. Tinea versicolor (Pityriasis versicolor or Chlo- asma). This disease consists of fawn-colored patches occurring in the parts covered by flannel, especially the front of the chest and the root of the neck. The patches vary in size, and may dot over the surface or run together so as to cover uniformly a large area. They are raised and itch}', and scales can be scraped from them, which under the micro- 96 THE DESCRIPTION AND scope are seen to be invaded by conidia (in heaps) and the mycelial threads (very wavy) of the fungus the microsporon furfur. The disease is some- times mistaken for syphilitic maculae, but the latter are not raised, not itchy, and not scurfy. Treatment Apply (127) regularly and for about ten days or so after all appearance of the disease has vanished. Tinea kerion is simply tinea tonsurans in which the hair follicles are a good deal inflamed and pour out an albuminous fluid. The special features of the disease are the general prominence of the patch; its perforation with foramina id ext. t he- swollen mouths of the hair follicles; the outpouring of a mucous fluid ; the non-suppuration of the swelling, which, although feeling boggy and ns about to suppurate, should never be opened; and the looseness of the hairs. The disease leaves temporary bald patches behind, and the fungus is observed to have invaded the hairs, as in tinea tonsurans. Treatment. Allay the inflammation; cpilate ; and then use some very mild parasiticide, as in ordinary ringworm. Tinea decalvans, see Alopecia. Urticaria, or Nettlerash The features that attract attention as altogether diagnostic of this affection are first I;/, tin- sudden way in which the erythematous rash appears and disappears, or, in other words, the capriciousness of the eruption ; TREATMENT OF BKIN DISEASES. 9T secondly, the development of "wheals," like those caused by the stings of nettles, in the centre of the red hyperaemic patches. It has differences as it occurs in the adult and child. In the adult the wheals are always well marked, and leave no trace of their presence behind when the}" disappear. The urticaria may be acute, gene- rally the result of some dietetic error for instance, the eating of shell-fish or some unwholesome irri- tating food, as potted meats, and there is pyrexia often of a severe character, with even vomiting and prostration. The skin itches dreadfully, and then out comes the wheal eruption. Sometimes the face is attacked and swells enormously, but the erup- tion at once discloses the nature of the case. In the child the wheals are not so distinct, and are followed by the development of little fleshy papules hence the term lichen urticatus. These papules become " pruriginous" in proportion as the disease is chronic. In both children and adults the disease may be primary and idiopathic, or secondary to some other disease, as scabies and phthiriasis. In the latter there will be a history of antecedent disease of the kind mentioned, and the actual concomitants of the symptoms of these diseases. In the idiopathic form the hyperaemia and wheals exist as the sole disease present. Treatment. In the adult in the acute form an emetic may be given if need be, with alkalies, and 9 98 THE DESCRIPTION AND a slight aperient. Chronic urticaria in the adult is much more troublesome. There is no pyrexia, l>ut constant recurrence of redness and wheals with heat and itching. Assuming the existence of an irritable state of skin, the eruption appears to be kept up by dyspepsia and uterine or liver disorder. Large doses of alkalies internally, followed by (95), and, if desirable, arsenic, with bran and alkaline baths (la and 16), or vapor baths if the skin does not act properly, are beneficial. Such lotions as (18), (23), (26), (27), (30), (31), (33), and many like ones may be used. A similar line of treatment must be adopted for the child in the early stages, though care should be taken to keep the kidneys acting well, and to give cod-liver oil if the health is poor. Locally, soothing remedies arc needed (74) ; but sulphuret of potassium baths in chronic cases are very efficacious. Ointments of storax or calomel and belladonna will be found successful in aiding accompanying pruritus, especially if excited by animal parasites, such as bugs, fleas, lice, etc. Vitiligoidea. This is the term applied to the buff-colored patches that form, especially at the inner canthus of the eye, in those who have suffered from chronic liver disorder and have had jaundice. It occurs also about the general surface of the body as yellow or buff nodules. The treatment required is that for hepatic disease. Xanthelasma as the term given by Mr. Wilson to Vitiligoidea. TREATMENT OP SKIN DISEASES. 99 Xanthelasmoidea is a term given to certain buff-colored patches that appear in a scattered form in young children, resembling Xanthelasma. It is, however, very rare, and has no connection with jaundice. Xeroderma, see Ichthyosis. Zoster, see Herpes. PART III. CUTANEOUS PHARMACOPOEIA. BATHS. 1. THE quantity of water in a bath is estimated at thirty gallon*, and the temperature of the water should be from 90 to 95 F. (a:) Bran and gelatine bath. The quantities to be used are of bran, 2 to 6 ft ; of gelatine, 1 to 3 tb ; or of size, 2 to 4 lb. Used in all erythematous and itchy and scaly diseases. (6.) An alkaline bath is made with from 3*ij to 3*x of bicarbonate of soda, or 3"iij of borax. It is some- times useful to add to the bicarbonate of soda some bran liquor made by infusing bran in hot water. Used in eczema, psoriasis, urticaria, lichen, and prurigo, where there is much local irritation. (c.) An acid bath is made with sj of nitric or muriatic acid or a mixture of the two (3j of each). Used in chronic lichen and prurigo. (d.) Sulphurated potash bath has gij to s"iv to each bath. The compound sulphur bath of Startin has 3*ij of sulphur (prrecip.), 5j of hyposulphite of soda, and 353 of dilute sulphuric acid with a pint of CAUSTICS. 101 water. Used in itch, chronic eczema, lichen, and psoriasis. FUMIGATION. 2. To administer a medicinal vapor bath, heat is to be applied simultaneously to the drug and a small tray of water, so that steam and the vapor of the drug may arise and surround the patient's body together. The necessary apparatus may be obtained at any instrument-maker's or easily be im- provised. A quarter of an hour should usually suffice for the proper action of the bath. For a mercurial bath fifteen to thirty grains of calomel, and for a sulphur bath from one to two ounces of sulphur should be used. CAUSTICS. 3. Calomel, Sijss; bisulphide of mercury, 9ij ; arseuious acid, 3j. Used in lupus, scrofulous ulcers, and syphilis. Dupuytren. 4. Caustic potash and water in equal parts. Use- ful in liqjus. 5. Acid nitrate of mercury, made by dissolving 3j of mercury in Ij of nitric acid (sp. gr. 1.40). Used in neoplasmata, etc. 6. Chromic acid, 3j ; water, 3iv. Used for warts, lupus, etc. 7. Powdered savin; perchloride of mercury; red oxide of mercury, aa 5j- Used for condylomata and warts. Langston Parker. 9* 102 CUTANEOUS PHARMACOI'(I A. 8. Carbolic acid, 1 part; alcohol, 1 4 parts. Used in lupus, syphilitic ulcers. 9. Nitrate of zinc, 1 part ; bread mass, 2 or 3 part--. Used in lupus, spread thinly on the part. ASTRINGENTS. Alum and Zinc. 10. Alum, gr. xx; sulphate of zinc, gr. x; glycerine, 5j ; rose water, oiv. Used in erythema, interlrigo, eczema. Tannic Acid. 11. Tannic acid, gr. xl ; French vinegar, % ss ; distilled water, 3viiss. Used in seborrhcea Neligan. Myrrh and Zinc. 1 2. Tincture of mj'rrh, gtt. xxx ; zinc oxide, gr. xx ; cold cream, 5J. Used in prurigo, erythema, lichen. Neligan. Bismuth and Vaseline. 13. Trisnitrate of bismuth, 9ij ; lead solution, 30 drops ; vaseline, 3j. For intertrigo, eczema, etc. Zinc and Glycerine. 14. Zinc oxide, 3U ; glycerine, 3U 5 lead water, Siss; lime water, svj to 5viij. Used in the secre- tory stage of eczema, in acne, lichen, foul ulcers, impetigo, herpes. SEDATIVES. 103 Borax and Glycerine. 15. Borax, 9j or 3J I glycerine, 5U 5 r ose water, 3viij. Used in squanious diseases. Acid and Lead. 10. Dilute hydrochloric or nitric acid, 3ss ; lead acetate, gr. v to x; glycerine, 5iss ; water, 3 V J- Used in eczema and lichen. Alum. IT. Alum, 5U 5 infusion of roses, .sxx. Used in acne* pityriasis^ and eczema (sine crustis). Cazenave. SEDATIVES. Soda. 18. Carbonate of soda, 5ss ; conium juice, j elderflower water, vj. Used in eczema, lichen, urticaria, to allay itching. 19. Bicarbonate of soda, 3 j 5 glycerine, Jiss ; elderflower water, viss. Used as above and in acne punctata. 20. Borax, 3ij 5 cherry laurel water, 3j 5 elder- flower water, o^ij. Used in lichen. Morphia. 21. Borax, ^ss; sulphate of morphia, gr. vj ; rose water, sviij. Used in pruritus vulvae. Meigs. 22. Solution of hydrochlorate of morphia, ^iss ; 104 CUTANEOUS PHARMACOPEIA. solution of potash, 5U ; glycerine, sj ; cherry laurel water, sj ; elderflo\vi.>r water, to 3"xij. Used in pruriginous eruption*. Hydrocyanic Acid. 23. Perchloride of mercury, gr. j ; dilute hydro- cyanic acid, 3J 5 emulsion of almonds, 3*vj. Used in itching, lichen, and prurigo. 24. Dilute hydroc3~anic acid, 5j 5 solution of ace- tate of ammonia, sij; tincture of digitalis, 5'U I rose water, 5\ r . Used in pruritus, prurigo, lichen, urticaria. Thomson. 25. Dilute hydrocyanic acid, 3ij ; borax, 5j ; rose water, sviij. Used in pruritus of old people. Neligan. Cyanide of Potassium. 26. Cyanide of potassium, gr. vj ; cochineal, gr. j ; cold cream, sj. Used in pruritis, urticaria. Anderson. 27. Cyanide of potassium, gr. xv; water, sviij. Used in pudendal irritation, lichen, and prurigo. Hardy. (N. B.) Keep it in a dark place. Chloroform. 28. Carbonate of lead, 3 SS 5 chloroform, n^iv ; cold cream, sj. Used in pruritus. 29. Cyanide of potassium, gr. iv ; chloroform n^viij ; glycerine, 5j 5 white wax ointment, 5 V J- Used in pruritus Neligan. SEDATIVES. 105 30. Chloroform, 3j ; glycerine, 5iv. Duparc. 31. Bichloride of mercury, gr. iss ; chloroform, n^xx ; glycerine, 5*ij 5 rose water, 3*vj. Used in itching, papular, and vesicular diseases, and urti- caria. Burgess. Belladonna. 32. Extract of belladonna, 3*ss; dilute hydro- cyanic acid, s*ss ; glycerine, |j ; water, 3"xiv. Used in papular and phlegmonous affections. Startin. Benzole Acid. 33. Benzoic acid, 40 to 60 grains to 3vj of water. Used in urticaria to allay itching. Ringer. Digitalis. 34. Tincture of digitalis, 3'j to ^iv; glycerine, 3"ss; rose water, 3 vj. Used in pruritus of a purely neurotic character. Lead. 35. Carbonate of lead, gr. iv; glycerine, 3J ; sim- ple cerate, j. Used in erythema. 36. Glycerine, subacetate of lead, and vaseline. Made by Squire, 2T7 Oxford Street. In intertrigo, eczema. Acetate of Ammonia. 37. Solution of acetate of ammonia, 3 ij ; alcohol, ^ss; rose water, ^iv. Used in lichen. Burgess. 106 CUTANEOUS PUARMACOP(EIA. Carbolic Acid. 38. Liquid carbolic acid, ss ; water to Oj. Used to allay itching in chronic eczema or psoriasis. Zinc. 39. Oxide of zinc, 5u ; solution oflead, 5j 5 wine of opium, 5j > PPPy decoction, iv. Used in eczema, herpes, etc. 40. Oxide of zinc, 5j 5 carbonate of lead, 5j 5 spermaceti, j ; olive oil, q. s. To make a soft ointment. Used in seborrhcea, where the skin is inflamed Neumann. Camphor. 41. Camphor, 3 s s; alcohol, q. s. ; oxide of zinc, starch, aa Jj. Used as a powder to allay burning heat of eczema. Anderson. 42. Camphor, gr. viij ; tincture of conium, 3U 5 simple cerate, |j. Neligan. 43. Camphor, 3ss or 3j ; alcohol, sj ; borax, 3ij ; rose water, sviij. Used in pruritus^ eczema, and the erylhemata. 44. Sulphate of atropine, gr. j; borax, 5ij ; gly- cerine, 5i'j ; distilled water to sxij. Used to allay pruritus in various diseases where skin is not abraded. Borax. 45. Borax, 9ij ; carbonate of soda, 3j ; gly- cerine, 3iss 5 dilute hydrocyanic acid, n^xxx; dis- STIMULANTS AND ABSORBENTS. 107 tilled water, ^vj. Used in vesicular and sebaceous diseases. 46. Borax, 9ij ; oxide of zinc, 5j I solution of subacetate of lead, 5U 5 lime water, SYJ to ^viij. Used in eczema and herpes. 47. Borax, 3j to 5ij ; glycerine, 5j ; lard, |j. Used in parasitic diseases, eczema, erythema, inter- trigo, lichen. ABSORBENT POWDERS. 48 (a). Powdered maize, |iv; oxide of zinc, j ; calamine, $ss. Used to excoriated surfaces. 48 (6). Powdered maize, iv; oxide of zinc, gj 5 iris powder, ^ss ; oil of almonds, gtts. x. 49. The white Fuller's earth, or Cimolite, pre- pared by Taylor, Baker Street. STIMULANTS AND ABSORBENTS. 50. Alcohol, oil-cade, soft soap, aa 5j ; oil of lavender, 5iss. Used in eczema and psoriasis. Anderson. 51. Soft soap, :|ij 5 spirits of wine, sj ; dissolve, filter, and add spirits of lavender, 5U- Used in seborrhosa. Kalicreme of Hebra. Iodide of Starch Paste. (Univ. Coll. Pharm.) 52. Powdered starch, 1 part ; glycerine, 2 parts ; water, 6 parts : boil together, and when nearly cold add solution of iodine, 1 part. Useful to cleanse and heal foul sores, especially such as are syphilitic. 108 CUTANEOUS PHARMACOPEIA. 53. Load plaster, 533 ; almond oil, 588 ; hcnzoati-il oxide of zinc ointment, sij. . To be used in eczema as an astringent dressing. 54. lodoform, gr. xxx-lx ; lard, sj. Used to dress painful burns, ulcers, chancres, and Mercurial. 55. Calomel, 5j J lai'd? 3J- Used in herpes, psoriasis, pruritus vulox. 56. The oleates of mercuiy, 5 and 10 per cent. Useful in ringworm, syphilis, sycosis, etc. 57. Green iodide of mercur}', gr. ij to gr. xv ; hu'd, oj- Used in acne. Hardy. 58. Calomel, 5j ; camphor, 3ss ; spirits of wine, q. s. ; lard, 5j. Used in pruritus of the anal region, and in syphilitic ulceration. 59. Bicyanide of mercury, gr. v to gr. x; lard, 5j. Used for syphilitic tubercles. 60. Red oxide of mercuiy, finely powdered, and ammoniated mercury, aa gr. vj ; lard, 3j. The " Unguentum mercuriale co." Used in sebaceous, squamous, ulcerous, tubercular, and papular erup- tions. Startin. 61. Iodine, 3ss ; glj^cerine, ,^ij ; olive oil, siijss; strong mercurial ointment, 3ij. The Linimentum hydrarg. et iodini of Startin. Used in tubercular and cachectic affections. 62. Ammoniated mercury, gr. xx ; nitrate of mercury ointment, gr. xx ; acetate of lead, gr. x; oxide of zinc, gr. xx ; purified palm oil, sss; fresh STIMULANTS AND ABSORBENTS. 10'J lard, 3ss. Used in eczema of the head, in children especially. 63. Nitrate of mercury ointment, 5j ; solution of lead, 5i gs > oxide of zinc, 5j ; carbolic acid, gr. v ; fresh lard, j. Used in inflamed or irritable psoriasis. Sulphur, 64. Iodide of sulphur, gr. x to 5j ; lard, 5j Used in acne. 65. Milk of sulphur, 5ij ; ether, Iss; spirits of wine, 5i'j ; glycerine, 5iij 5 r ose water, svj. To be dabbed on to indolent acne, indurata, or rosacea, allowed to remain a moment or two, and then dried off with linen. 66. Hypochloride of sulphur, 5U > carbonate of potash, gr. x ; lard, gj ; oil of bitter almonds, gtt. x. Used in acne Wilson. 67. Sulphur, glycerine, rectified spirits of wine, carbonate of potash, sulphuric ether, equal parts. To be rubbed on to the part affected with comedo with friction. Tar. 68. Tar, alcohol, aa 3j. Used in psoriasis chiefly. 69. Pyroligneous oil of juniper, 5j to 3j ; mutton suet, 3ss ; -lard, 3j. Used in eczema and psoriasis palmaris, etc. 70. Tar, 5j 5 camphor, gr. x; lard, 5*. Used in pruritus, and in vesicular and papular diseases. Baume". 10 110 CUTANEOUS I' II A R M A C O P IE I A . 71. Detergent solution of tar, 5'j to sj ; glyce- rine, 5ij 5 rose water to sviij. Used in chronic scaly, itchy conditions (dilute hydrocyanic acid may In- added, n^xxx). Silver. 72. Silver nitrate, gr. ij to gr. x ; water, sj. Used in eczema and erythemata. Bismuth. 73. Bismuth nitrate, 5'j ; mercuiy perchloride, gr. x ; spirits of camphor, 3ss ; water, q. s. ad sxvj. Lotio bismuthi nitratis. Used in sebaceous, puslu- lar, and vesicular diseases, and in pifyriasis. Use diluted with 1 to 3 parts water. Startin. Zinc. 74. Oxide of zinc, 5\j > calamine powder, sss ; glycerine, 5'j 5 rose water, svj. Used in eczema, especially where the surface is red and tender. A grain of the perchloride of mercury may be added. 75. Sulphate of zinc, 5 SS 5 oxide of zinc, 5j; alum, 5 j 5 glycerine, 5'j 5 r ose water to 3vj or more. Used in scaly stages of eczema, indolent in- tertrigo, etc. Hebrd's Ung. DiacTiyli. 76. This is made by boiling together olive oil, 3 xv, and litharge, ^iij et 5 v ji to a good consistence, and adding oil of lavender, 5ij- Used in eczema, applied twice a day on linen. MIXTURES. Ill 17. Subcarbonate of soda, 3U ; extract of opium, gr. x; slaked lime, 5j 5 lead, ^ij. Used for severe itching in prurigo. Biett. 78. Nitrate of mercury ointment, 3ij 5 campho- rated oil, glj'cerine, aa *ss. Used in psoriasis. PLASTERS. 79. Camphor, $ss ; black pitch, 5vj ; yellow wax, 5ix ; red oxide of lead, ijij ; olive oil, .51 v. To be melted together till a little burned. Used in boils. (Emplastrum fuscum.) 80. Mercury, ^iv ; turpentine, 3ij 5 yellow wax, 3iij ; lead plaster, oi ss - Used in acne rosacea Neumann. (Emplastrum hydrargyri.) 81. Mercurial plaster, soap plaster, aa oj- Used for syphilitic papules, tubercles, and indurations generally. 82. Ammoniated mercury, 3ss; soap plaster, ss. Used in syplnlitic excoriations and ulcerations. Sigmund. 83. Red oxide of mercury, 3ss ; ammoniated mer- cury, 3 SS I soap plaster, oU- Used in syphilitic cracks and fissures about the hands, indurations, etc. MIXTURES. 84. Perchloride of mercury, gr. T \ to ^ ; dilute hydrochloric acid, gtt. x; water, |j. Take for one dose. 85. Perchloride of mercury, gr. j ; iodide of po- 112 CUTANEOUS PHARMACOPOEIA. tassium, 5U ; water, siij. A dessertspoonful throe times a clay. Used in acne Burgess. 86. Perchloride of mercury, gr. T J ff ; iodide of po- tassium, gr. v; compound tincture of iodine, n^iij ; water, ^iss. Twice a day. Used in syphilis. 87. Perchloride of mercury, gr. to ^ ; arscnious acid, gr. ^ to ^ ; water, Jss. For one dose in chronic syphilis. 88. Iodide of potassium, 3ss Jiij ; sal volatile, 5iij ; syrup of orange-peel, 5iv ; water to sviij. A sixth part with half a tumbler of water twice a day. The dose of iodide of potassium may be increased gradually up to gr. xxx if required.. Used in secon- dary and tertiary syphilis. 89. Iodide of potassium 5 s s and upwards ; po- tass io-tart rate of iron, 3 j 5 syrup, sss; water, s*vj. One-sixth part for a dose in chronic syphilis in anaemic subjects. 90. Wine of ijron, 3*iss ; simple syrup, sss; Fowler's solution, gtt. xlviij ; distilled water, to S*vj. Dose: a tablespoonful twice or thrice a d;iy. 91. Fowler's solution, n^lxxx; iodide of potas- sium, gr. xvj ; iodine, gr. iv ; orange-flower w:iU-r, Sij. Dose: a teaspoonful with water three times a day. Used in eczema. Neligan. 92. Cod-liver oil, 3ij ; yolk of egg, ny ; Fowler's solution, rtLlxiv ; syrup, 3'j 5 distilled water, q. s. ad siv. Dose: one teaspoonful three times a day. Wilson. MIXTURES. 113 93. Arscniate of soda, gr. i to ij : distilled water, 5\ - iij. Dose: one tablespoonful twice daily. 94. Hydrochloric solution of arsenic, 3ss ; dilute hydrochloric acid, 5j 5 tincture of the perchloride of iron, 3iss to Jiij 5 water, 3*viij. Dose: a sixth part three times a day. In psoriasis and eczema in anaemic subjects. 95. Sulphate of magnesia, 5iij ; sulphate of iron, gr. xij ; dilute sulphuric acid, 5ss; infusion of quas- sia, q. s. ad sviij. Dose : one-sixth part twice daily. Used in acne, eczema, impetigo, and ulcerous affec- tions. Quinine may be added if desirable. 96. Sulphate of magnesia, 5iv; carbonate of magnesia, Jj ; tincture of colchicum, n^xxxvj ; oil of peppermint, n^ij ; water, 3*viij. Dose: a sixth part. Used in crythemata, popular, and acute forms of disease in loaded habits. 97. Bicarbonate of soda, Jiij; tincture of calumba, 5'iij ; sal volatile, 5iij j dilute hydrocyanic acid, n^viij ; syrup of ginger, 5iij I water, 5\-j. Dose: a sixth part an hour before two principal meals. Used in dyspepsia. 98. Acetate of potash, 3j ; acetic acid, Jss ; spirits of nitrous ether, ,?iss; fluid extract of taraxacum, 3 i]< Dose: a teaspoonful with water before meals. Used in acne indurata Bulkley. 99. Iodide of sodium, gr. Ix; compound decoction of sarsaparilla, o v HJ- Dose: a sixth part three times a day in obstinate syphilitic eruptions, where iodide of potassium disagrees or fails. 10* 114 CUTANEOUS P II A R M A C P ( I A . 100. Turpentine rectified, 5ss to3iss; crensote, n^iij; spirits of rosemary, n\,xl ; water, q. s. ad iv. Dose: two teaspoonfuls every three hours. Used mpurpura. Budd. 101. Acid tartrate of potash, 5iij ; decoction of broom, gvj. Dose : two tablespoonfuls three times a day. Used as a diuretic and aperient in eczema of the legs with oedema. 102. Acetate of potash, 3i'j 5 vinegar of squill, 5iij ; sweet spirits of nitre, n^xx ; compound decoction of broom, Sviij. Dose: a sixth part thrice a da} r . Used as a diuretic, where the skin is very hypenemic and the urine not freely voided. Digitalis may be added if desired. 103. Strychnine, gr. ^ 1 ; dilute phosphoric acid, 5'ij ; tincture of orange-peel, 3ss ; infusion of cloves, 3xj. Dose: half an ounce three times a da} r . Used in prurigo and lichen. PILLS. 104. Red iodide of mercury, gr. j to ij ; extract of gentian, 9 ij. Make 12 pills. One pill twice a day. 105. Bicyanide of mercury, gr. j; quinine, gr. xx ; extract of gentian, gr. xxx. To make 20 pills. One twice a day. Used in ordinary syphilitic eruptions. 106. Arseniate of soda, gr. ij ; water sufficient to dissolve; guaiacum powder, 5ss ; sulphurated mer- cury, 9j. Mucilage sufficient to make 24" pills. REMEDIES FOR PHTIIIRIASIS. 115 One pill two or three times a day. Used in chronic skin diseases. Wilson. 107. Levigated arsenious acid, gr. v ; powdered acacia, 5 SS j cinnamon powder, 5*0 > glycerine, enough to make 100 pills. (Pil. arsenicalis comp.) Dose : one or two a day. 108. Arsenious acid, gr. j; quinine, gr. 20-30; dried sulphate of iron or reduced iron, gr. xl-lx ; extract of hop, gr. x ; extract of gentian, q. s. To be well mixed and divided into 20 or 16 pills. One twice a day after a meal.. Used in chronic skin diseases with debility. 109. Quinine gr. 1 to 2; reduced iron gr. ij ; ex- tract of mix vomica gr. ^ ; extract of chamomile gr. j. To be taken twice or thrice a day. REMEDIES FOR SCABIES AND PHTHIRTASIS. 110. Sulphurated potash, ^vj ; hard soap, fbij ; olive oil, Oij ; oil of thyme, 3ij. Used in scabies and prurigo. 111. Olive oil, Jij; sulphate of potash, 3xv; sulphate of soda, 3xv; precipitated sulphur, 3x Used in scabies. Mollard. 112. Sulphur, tar, aa 3vj ; soft soap, lard, aa ^xvj ; chalk, Jiv. Used in scabies. Hebra. 113. Lard, ij ; sulphur, 3v ; carbonate of potash, water, aa 3ij. Used in scabies. Hardy. 114. Sublimed sulphur, Jss; ammoniated mer- 11C CUTANEOUS P H A R M A C O P (K I A . cury, gr. v; creasote, gtt. iv; olive oil, 5U ; hirtl, oj. Used in scabies. 115. Olive oil, 3"ss ; lard, 5~ss; powdered acre, 5VJ- Soak the stavesacre in hot oil and mix. Used in phthiriasis. 116. Quicklime, Ibj ; flowers of sulphur, Ibij ; water, Ibxx. Boil until 12tb remain, and then filter. Used in scabies Vlemingk's Solution. 117. Iodide of potassium ointment is very efficacious in scabies. 118. Sulphur ointment, 5ij ; oil of chamomile, gtt. xx. Used in scabies. 119. For phthiriasis the ordinary white precipi- tate ointment of the Pharmacopoeia is as good a remedy as any, diluted from 5 to 10 times. 120. Liquid storax, 3 j 5 lard, sij. Melt and strain. Used in scabies. Anderson. A little sul- phur may be added if thought desirable. REMEDIES FOR VEGETABLE PARASITIC DISEASES. 121. Perchloride of mercury, gr. x to xx ; elder- flower ointment, oj- Used in the early stages of fovus and tinea tonsurans. 122. Carbolic acid, 3j 5 glycerine, 333 to 3jj. Used in linea tonsurans. Or the same with rose water, siv, in tinea circinata. 123. Hyposulphite of soda, 3 iij ; dilute sulphurous acid, 3ss; water, q. s. ad 3"xvj. Used in all forms of parasitic disease. Startin. REMEDIES FOR PARASITIC DISEASES. 117 124. Perchloride of mercury, gr. ij toiv; alcohol, 5iv ; chloride of ammonium, 5ss ; rose water, q. s. ad 3vj. Used in scabies, phthiriasis, and tinea versicolor. 125. Saturated solution of sulphurous acid, 1 part ; water, 2-4 parts. Used in all the tinese. 126. Pyroligneous oil of juniper, 5ij to 5iv ; lard, ^iiss. Used in tinea. 127. Hyposulphite of soda, 5iv; glycerine, -;j ; distilled water, |vj. Used in pruritus vulvas and tinea versicolor. 128. Ammoniated mercury, gr. yj-xxx ; red oxide of mercury, powdered, gr. vj xxx ; lard, j. Used in all forms of ringworm. Startin. 129. Strong ammonia liniment, ^ss; castor oil, 3ss; spirits of turpentine, purified, ^ss; ammoniated mercury, gr. xv. Brush into the scalp with a hard brush until irritation is set up. For Baldness. 130. Tincture of cantharides, |j ; distilled vinegar, 3iss ; glycerine, 5iss > spirits of rosemary, iss ; rose water, Sviij. To be well sponged into the scalp night and morning. 131. Blistering fluid, 5j 5 sulphate of zinc, gr. xx ; balsam of Peru, 5iss ; powdered galls, 5U 5 lard, j. For tinea tonsurans. 132. Subacetate of copper, gr. xxx; birch oil, 5iij ; lard, 3j. Same: 133. Sulphur, tar, tincture of iodine, aa j ; lard, 3J. Same. 134. Carbolic acid, 3j ; sublimed sulphur, 5"j 5 118 CUTANEOUS PHARMACOPEIA. tincture of iodine, 5'ij ; vaseline (gclatum petmlci) or lard, 5j- In tinea tonsurans. 135. Blistering fluid, 5j ; sulphate of copper, 9ij ; powdered galls, 3j ; vaseline, 3j. For ringworm. 136. Iodine, 3j ij I colorless oil of wood tar, Sj. This preparation is known as " Coster's pa-tr." DIET IN SKIN DISEASES. There are one or two observations to be made on this subject that may be of use in the management of these diseases. Firstly A distinction must be made between the diet of the private and hospital patient. The latter often only requires to be well fed up, and his disease then speedily goes ; the former, on the other hand, often needs to have a check put on the quan- tity and quality of his food. Secondly. In children skin diseases may arise directly from defective alimentation, as in the case of eczema; and it is frequently the case that the child, the subject of eczema, intertrigo, or psoriasis, has not a sufficient supply of milk, either from excessive dilution or otherwise. Thirdly. The regulation of the diet, setting aside the question of quantity or quality, is as a rule needed not so much to directly influence the skin disease as certain states of the general health ; which modify the particular disease present ; for instance to meet especially dyspeptic, gouty, and rheumatic conditions, but particularly the former. DIET IN SKIN DISEASES. 119 In dyspepsia in connection with eczema, acne, psoriasis, or congestion of the face, it is advisable, especially if the urine be very acid, to avoid sugar, tea, coffee, alcoholics, beer, raw vegetable matter, with unripe or uncooked fruit, veal, pork, seasoned dishes, pastry, and the coarser kinds of vegetables, but especiall}' all articles whose use is followed by heat or flushing of the face and by flatulence and the like. Milk, the common meats, a light kind of bread, and some very light wine should be the diet of dyspeptic patients, whose skins are at all in a state of irritation. In very many cases the stomach is at fault at the outset, and a careful regulation of the diet is of the utmost importance as an aid to the other means adopted to correct faults in other parts of the 83- stem. In gouty subjects much the same line is to be pursued. As regards stimulants, hock, a good light claret, Moselle even, but not the sparkling, or whisky in Vals water, are the best beverages. In strumous subjects, the diet should consist of as much fatty matter as possible. Fourthly. In children who suffer from ringworm, it is desirable to give as much fatty matter as possi- ble, by means of milk, cream, eggs, and fat meat if they be got to eat it. Fifthly. In syphilis, the greatest care should be taken to avoid anything beyond the most moderate use of stimulants: their abuse in this disease is a source of the greatest aggravation. 120 CUTANEOUS PHARMACOPOEIA. Sixthly. In all cases in which the onset or early stage of a skin disease is accompanied by i'ebrilc disturbance, however slight, or in which the disease is very hyperji'inic. stimulants should be avoided, and the plainest and simplest diet ordered. In marked cases of this kind, a milk diet for a while is often found to be very beneficial. Seventhly. In some cases in which the skin is hyperremic, this condition is much increased by the ingestion of food, especially if dyspepsia exists, in consequence of the sympathy existing between the stomach and the skin of the part affected. This state of things is especially marked in such discuses as acne, congestion of the face, and non-parasitic sycosis. Stimulants must be avoided, except they be diluted with some alkaline water: the use of a diet appropriate to the dyspepsia must be rigorously enforced. Eighthly. It is said that psoriasis requires an ample meat diet ; but the patient must be dieted, and not his disease i. e., the diet should be plain and nutritious, and adapted to the constitutional peculiarities of the individual according to circum- stances. Ninthly. In all cases where a skin disease has become chronic, and where there is debility, the patient should be allowed a fall, unstimulating diet. THE END. University of California SOUTHERN REGIONAL LIBRARY FACILITY 405 Hilgard Avenue, Los Angeles, CA 90024-1388 Return this material to the library from which it was borrowed. JAN \ 1876 Fox, Tilbury* Epitoire of skin diseases. MEDICAL SCIENCES LIBRARY UNIVERSITY OF CALIFORNIA, IRVINE IRVINE, CALIFORNIA 92664 1970 01953 6934